4AOKB

Conformational dynamics of aspartate alpha-decarboxylase active site revealed by protein-ligand complexes: 1-methyl-l-aspartate complex
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
98
structure length
98
Chain Sequence
CAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Dynamics of Aspartate Alpha Decarboxylase Active Site Revealed by Protein-Ligand Complexes
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords ASPARTATE 1-DECARBOXYLASE BETA CHAIN
total genus 24
structure length 98
sequence length 98
chains with identical sequence E
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2012-03-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4aokB00
4GA5A 2E2IA 4KDLA 2VPYA 1TWGA 1TMOA 1SIWA 2JIMA 5EPPA 4D7ZB 1PQFA 5FTNA 1AA6A 2Y0SA 1E32A 1R7RA 1E61A 1YLEA 2V3VA 1SFOA 5FTJA 1EU1A 1K83A 4CRYG 5DYGA 1TWHA 1G8JA 3PLXB 5T5MD 3CQZA 1PPYA 3GTJA 3GTQA 1FDIA 1OGYA 4KODA 1DMRA 1PYUB 5B6CA 3ML1A 3H0GA 1R9TA 2R7ZA 2JIOA 3HU3A 3GTGA 5FTMA 2B63A 1KQGA 2WB1A 3GTOA 3QC8A 2NYAA 2IV2X 3OUGA 1QDNA 1VC3B 1E60A 4RV0A 1R27A 3QQ8A 1FDOA 4CS0A 1E18A 3TIWA 4AAYA 1G8KA 1Y4ZA 2EEOB 1PQHA 5C1BA 4QIWA 5FTLA 2VUMA 1TWFA 1UHDA 1PYQA 4DMRA 2JA7A 3HU1A 1Q16A 4AZDA 2E2HA 1IW7D 2R92A 5T5ID 1H0HA 1PT0A 3O5AA 4KLNA 2V45A 1PQEA 2KI8A 3HU2A 1QCSA 1E5VA 4AYBA 2PMZA 2WAQA 2R93A 2VPXA 3GTLA 1CZ4A 2VPZA 1I3QA 2NAPA 3HKZA 1WLFA 3GTPA 1PT1A 5FTKA 2DMRA 4GA6A 2PJHB 1UHEA 1WCMA 2JIQA 4KO8A 3CF2A 4KDIA 4AOKB 4AONB 5DYIA 1Y1WA 1TWAA 2JA5A 3GTKA 2NVXA 2NVYA 3FKIA 3IR5A 2YU9A 2VPWA 4C2MA 3IR6A 3QWZA 3IR7A 3TM7B 3DMRA 3QQ7A 2JIRA 1Y5IA 2JA6A 1DMSA 5C18A 1TWCA 1H5NA 2C45A 1Y1VA 4CRZA 1KQFA 2JIPA 1CZ5A 1CR5A 1AW8B 1S3SA 1I50A 5GLFA 3GTMA 2E7ZA
chains in the Genus database with same CATH superfamily
4GA5A 3SUJA 2E2IA 1YNND 4KDLA 2VPYA 1TWGA 1TMOA 1SIWA 2JIMA 4JJOA 2HCZX 3X2KA 2A68D 3SULA 5EPPA 5GM9A 4D7ZB 1PQFA 5FTNA 1AA6A 2Y0SA 1E32A 1R7RA 1E61A 1YLEA 3X2LA 2V3VA 2GAEA 1SFOA 4JS7A 4FERA 5FTJA 4NOHA 1EU1A 5H4UA 1K83A 4CRYG 2G5DA 5DYGA 2AE0X 1TWHA 3X2MA 2PJJA 1G8JA 2YUJA 3PLXB 5T5MD 3CQZA 1PPYA 3GTJA 4JCWA 3GTQA 1OGYA 1FDIA 4KODA 1DMRA 1PYUB 3M3GA 5B6CA 3ML1A 1N10A 3H0GA 1L8FA 1R9TA 2R7ZA 4ZM7A 3X2IA 2JIOA 3HU3A 4FG2A 4JP7A 3GTGA 5FTMA 2B63A 2BH0A 1KQGA 2WB1A 3GTOA 3X2JA 3QC8A 3X2GA 2NYAA 2IV2X 3OUGA 1QDNA 1VC3B 1E60A 4RV0A 1R27A 3QQ8A 1FDOA 4CS0A 1E18A 1OA7A 3TIWA 4AAYA 1G8KA 2ENGA 1Y4ZA 2O5JD 2EEOB 1PQHA 5C1BA 2PI8A 4QIWA 3SUKA 5FTLA 2VUMA 1TWFA 1OA9A 1PYQA 1UHDA 4DMRA 3HU1A 1Q16A 2JA7A 4AZDA 2E2HA 1IW7D 2R92A 3SUMA 5T5ID 1H0HA 1PT0A 3O5AA 3X2NA 1SMYD 4KLNA 2V45A 1PQEA 2KI8A 3HU2A 3X2PA 1QCSA 1E5VA 4AYBA 3X2OA 2PMZA 2WAQA 2A6HD 2R93A 2VPXA 3GTLA 2G6GA 1CZ4A 2KQAA 2VPZA 4FFTA 1I3QA 2NAPA 3HKZA 1WLFA 3GTPA 1PT1A 1YNJD 5FTKA 2DMRA 4GA6A 1UHEA 2PJHB 1WCMA 2JIQA 4KO8A 3CF2A 2CW0D 4KDIA 4AOKB 4AONB 5DYIA 5GLYA 1Y1WA 1TWAA 2JA5A 1BW4A 3GTKA 3D30A 2NVXA 2NVYA 3X2HA 3FKIA 3IR5A 2PNWA 2YU9A 2VPWA 2PICA 4C2MA 4JP6A 1BW3A 3IR6A 1ZYRD 2A69D 2A6ED 3QWZA 3IR7A 3TM7B 3DMRA 4L48A 4FG4A 1ZC1A 3QQ7A 2JIRA 1Y5IA 4ENGA 2JA6A 1DMSA 5C18A 1TWCA 1H5NA 2C45A 1Y1VA 2BE5D 1HD5A 1WC2A 5GLXA 4AVRA 4CRZA 1KQFA 2JIPA 3CZBA 3ENGA 1CZ5A 1CR5A 1AW8B 1S3SA 1I50A 5GLFA 3GTMA 2E7ZA
chains in the Genus database with same CATH topology
4GA5A 2E2IA 1YNND 4KDLA 2VPYA 1TWGA 1TMOA 1SIWA 2JIMA 2A68D 5EPPA 4D7ZB 1PQFA 5FTNA 1AA6A 2Y0SA 1E32A 1R7RA 1E61A 1YLEA 2V3VA 2GAEA 1SFOA 5FTJA 4NOHA 1EU1A 1K83A 4CRYG 2G5DA 5DYGA 2AE0X 1TWHA 2PJJA 1G8JA 2YUJA 3PLXB 5T5MD 3CQZA 1PPYA 3GTJA 3GTQA 1FDIA 1OGYA 4KODA 1DMRA 1PYUB 5B6CA 3ML1A 3H0GA 1R9TA 2R7ZA 2JIOA 3HU3A 3GTGA 5FTMA 2B63A 1KQGA 2WB1A 3GTOA 3QC8A 2NYAA 2IV2X 3OUGA 1QDNA 1VC3B 1E60A 4RV0A 1R27A 3QQ8A 1FDOA 4CS0A 1E18A 3TIWA 4AAYA 1G8KA 1Y4ZA 2O5JD 2EEOB 1PQHA 5C1BA 2PI8A 4QIWA 5FTLA 2VUMA 1TWFA 1UHDA 1PYQA 4DMRA 2JA7A 3HU1A 1Q16A 4AZDA 2E2HA 1IW7D 2R92A 5T5ID 1H0HA 1PT0A 3O5AA 1SMYD 4KLNA 2V45A 1PQEA 2KI8A 3HU2A 1QCSA 1E5VA 4AYBA 2PMZA 2WAQA 2A6HD 2R93A 2VPXA 3GTLA 2G6GA 1CZ4A 2VPZA 1I3QA 2NAPA 3HKZA 1WLFA 3GTPA 1PT1A 1YNJD 5FTKA 2DMRA 4GA6A 1UHEA 2PJHB 1WCMA 2JIQA 4KO8A 3CF2A 2CW0D 4KDIA 4AOKB 4AONB 5DYIA 1Y1WA 1TWAA 2JA5A 3GTKA 2NVXA 2NVYA 3FKIA 3IR5A 2PNWA 2YU9A 2VPWA 2PICA 4C2MA 3IR6A 1ZYRD 2A69D 2A6ED 3QWZA 3IR7A 3TM7B 3DMRA 1ZC1A 3QQ7A 2JIRA 1Y5IA 2JA6A 1DMSA 5C18A 1TWCA 1H5NA 2C45A 1Y1VA 2BE5D 4CRZA 1KQFA 2JIPA 3CZBA 1CZ5A 1CR5A 1AW8B 1S3SA 1I50A 5GLFA 3GTMA 2E7ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GA5 A;  2E2I A;  4KDL A;  2VPY A;  1TWG A;  1TMO A;  1SIW A;  2JIM A;  5EPP A;  4D7Z B;  1PQF A;  5FTN A;  1AA6 A;  2Y0S A;  1E32 A;  1R7R A;  1E61 A;  1YLE A;  2V3V A;  1SFO A;  5FTJ A;  1EU1 A;  1K83 A;  4CRY G;  5DYG A;  1TWH A;  1G8J A;  3PLX B;  5T5M D;  3CQZ A;  1PPY A;  3GTJ A;  3GTQ A;  1FDI A;  1OGY A;  4KOD A;  1DMR A;  1PYU B;  5B6C A;  3ML1 A;  3H0G A;  1R9T A;  2R7Z A;  2JIO A;  3HU3 A;  3GTG A;  5FTM A;  2B63 A;  1KQG A;  2WB1 A;  3GTO A;  3QC8 A;  2NYA A;  2IV2 X;  3OUG A;  1QDN A;  1VC3 B;  1E60 A;  4RV0 A;  1R27 A;  3QQ8 A;  1FDO A;  4CS0 A;  1E18 A;  3TIW A;  4AAY A;  1G8K A;  1Y4Z A;  2EEO B;  1PQH A;  5C1B A;  4QIW A;  5FTL A;  2VUM A;  1TWF A;  1UHD A;  1PYQ A;  4DMR A;  2JA7 A;  3HU1 A;  1Q16 A;  4AZD A;  2E2H A;  1IW7 D;  2R92 A;  5T5I D;  1H0H A;  1PT0 A;  3O5A A;  4KLN A;  2V45 A;  1PQE A;  2KI8 A;  3HU2 A;  1QCS A;  1E5V A;  4AYB A;  2PMZ A;  2WAQ A;  2R93 A;  2VPX A;  3GTL A;  1CZ4 A;  2VPZ A;  1I3Q A;  2NAP A;  3HKZ A;  1WLF A;  3GTP A;  1PT1 A;  5FTK A;  2DMR A;  4GA6 A;  2PJH B;  1UHE A;  1WCM A;  2JIQ A;  4KO8 A;  3CF2 A;  4KDI A;  4AOK B;  4AON B;  5DYI A;  1Y1W A;  1TWA A;  2JA5 A;  3GTK A;  2NVX A;  2NVY A;  3FKI A;  3IR5 A;  2YU9 A;  2VPW A;  4C2M A;  3IR6 A;  3QWZ A;  3IR7 A;  3TM7 B;  3DMR A;  3QQ7 A;  2JIR A;  1Y5I A;  2JA6 A;  1DMS A;  5C18 A;  1TWC A;  1H5N A;  2C45 A;  1Y1V A;  4CRZ A;  1KQF A;  2JIP A;  1CZ5 A;  1CR5 A;  1AW8 B;  1S3S A;  1I50 A;  5GLF A;  3GTM A;  2E7Z A; 
#chains in the Genus database with same CATH topology
 4GA5 A;  3SUJ A;  2E2I A;  1YNN D;  4KDL A;  2VPY A;  1TWG A;  1TMO A;  1SIW A;  2JIM A;  4JJO A;  2HCZ X;  3X2K A;  2A68 D;  3SUL A;  5EPP A;  5GM9 A;  4D7Z B;  1PQF A;  5FTN A;  1AA6 A;  2Y0S A;  1E32 A;  1R7R A;  1E61 A;  1YLE A;  3X2L A;  2V3V A;  2GAE A;  1SFO A;  4JS7 A;  4FER A;  5FTJ A;  4NOH A;  1EU1 A;  5H4U A;  1K83 A;  4CRY G;  2G5D A;  5DYG A;  2AE0 X;  1TWH A;  3X2M A;  2PJJ A;  1G8J A;  2YUJ A;  3PLX B;  5T5M D;  3CQZ A;  1PPY A;  3GTJ A;  4JCW A;  3GTQ A;  1OGY A;  1FDI A;  4KOD A;  1DMR A;  1PYU B;  3M3G A;  5B6C A;  3ML1 A;  1N10 A;  3H0G A;  1L8F A;  1R9T A;  2R7Z A;  4ZM7 A;  3X2I A;  2JIO A;  3HU3 A;  4FG2 A;  4JP7 A;  3GTG A;  5FTM A;  2B63 A;  2BH0 A;  1KQG A;  2WB1 A;  3GTO A;  3X2J A;  3QC8 A;  3X2G A;  2NYA A;  2IV2 X;  3OUG A;  1QDN A;  1VC3 B;  1E60 A;  4RV0 A;  1R27 A;  3QQ8 A;  1FDO A;  4CS0 A;  1E18 A;  1OA7 A;  3TIW A;  4AAY A;  1G8K A;  2ENG A;  1Y4Z A;  2O5J D;  2EEO B;  1PQH A;  5C1B A;  2PI8 A;  4QIW A;  3SUK A;  5FTL A;  2VUM A;  1TWF A;  1OA9 A;  1PYQ A;  1UHD A;  4DMR A;  3HU1 A;  1Q16 A;  2JA7 A;  4AZD A;  2E2H A;  1IW7 D;  2R92 A;  3SUM A;  5T5I D;  1H0H A;  1PT0 A;  3O5A A;  3X2N A;  1SMY D;  4KLN A;  2V45 A;  1PQE A;  2KI8 A;  3HU2 A;  3X2P A;  1QCS A;  1E5V A;  4AYB A;  3X2O A;  2PMZ A;  2WAQ A;  2A6H D;  2R93 A;  2VPX A;  3GTL A;  2G6G A;  1CZ4 A;  2KQA A;  2VPZ A;  4FFT A;  1I3Q A;  2NAP A;  3HKZ A;  1WLF A;  3GTP A;  1PT1 A;  1YNJ D;  5FTK A;  2DMR A;  4GA6 A;  1UHE A;  2PJH B;  1WCM A;  2JIQ A;  4KO8 A;  3CF2 A;  2CW0 D;  4KDI A;  4AOK B;  4AON B;  5DYI A;  5GLY A;  1Y1W A;  1TWA A;  2JA5 A;  1BW4 A;  3GTK A;  3D30 A;  2NVX A;  2NVY A;  3X2H A;  3FKI A;  3IR5 A;  2PNW A;  2YU9 A;  2VPW A;  2PIC A;  4C2M A;  4JP6 A;  1BW3 A;  3IR6 A;  1ZYR D;  2A69 D;  2A6E D;  3QWZ A;  3IR7 A;  3TM7 B;  3DMR A;  4L48 A;  4FG4 A;  1ZC1 A;  3QQ7 A;  2JIR A;  1Y5I A;  4ENG A;  2JA6 A;  1DMS A;  5C18 A;  1TWC A;  1H5N A;  2C45 A;  1Y1V A;  2BE5 D;  1HD5 A;  1WC2 A;  5GLX A;  4AVR A;  4CRZ A;  1KQF A;  2JIP A;  3CZB A;  3ENG A;  1CZ5 A;  1CR5 A;  1AW8 B;  1S3S A;  1I50 A;  5GLF A;  3GTM A;  2E7Z A; 
#chains in the Genus database with same CATH homology
 4GA5 A;  2E2I A;  1YNN D;  4KDL A;  2VPY A;  1TWG A;  1TMO A;  1SIW A;  2JIM A;  2A68 D;  5EPP A;  4D7Z B;  1PQF A;  5FTN A;  1AA6 A;  2Y0S A;  1E32 A;  1R7R A;  1E61 A;  1YLE A;  2V3V A;  2GAE A;  1SFO A;  5FTJ A;  4NOH A;  1EU1 A;  1K83 A;  4CRY G;  2G5D A;  5DYG A;  2AE0 X;  1TWH A;  2PJJ A;  1G8J A;  2YUJ A;  3PLX B;  5T5M D;  3CQZ A;  1PPY A;  3GTJ A;  3GTQ A;  1FDI A;  1OGY A;  4KOD A;  1DMR A;  1PYU B;  5B6C A;  3ML1 A;  3H0G A;  1R9T A;  2R7Z A;  2JIO A;  3HU3 A;  3GTG A;  5FTM A;  2B63 A;  1KQG A;  2WB1 A;  3GTO A;  3QC8 A;  2NYA A;  2IV2 X;  3OUG A;  1QDN A;  1VC3 B;  1E60 A;  4RV0 A;  1R27 A;  3QQ8 A;  1FDO A;  4CS0 A;  1E18 A;  3TIW A;  4AAY A;  1G8K A;  1Y4Z A;  2O5J D;  2EEO B;  1PQH A;  5C1B A;  2PI8 A;  4QIW A;  5FTL A;  2VUM A;  1TWF A;  1UHD A;  1PYQ A;  4DMR A;  2JA7 A;  3HU1 A;  1Q16 A;  4AZD A;  2E2H A;  1IW7 D;  2R92 A;  5T5I D;  1H0H A;  1PT0 A;  3O5A A;  1SMY D;  4KLN A;  2V45 A;  1PQE A;  2KI8 A;  3HU2 A;  1QCS A;  1E5V A;  4AYB A;  2PMZ A;  2WAQ A;  2A6H D;  2R93 A;  2VPX A;  3GTL A;  2G6G A;  1CZ4 A;  2VPZ A;  1I3Q A;  2NAP A;  3HKZ A;  1WLF A;  3GTP A;  1PT1 A;  1YNJ D;  5FTK A;  2DMR A;  4GA6 A;  1UHE A;  2PJH B;  1WCM A;  2JIQ A;  4KO8 A;  3CF2 A;  2CW0 D;  4KDI A;  4AOK B;  4AON B;  5DYI A;  1Y1W A;  1TWA A;  2JA5 A;  3GTK A;  2NVX A;  2NVY A;  3FKI A;  3IR5 A;  2PNW A;  2YU9 A;  2VPW A;  2PIC A;  4C2M A;  3IR6 A;  1ZYR D;  2A69 D;  2A6E D;  3QWZ A;  3IR7 A;  3TM7 B;  3DMR A;  1ZC1 A;  3QQ7 A;  2JIR A;  1Y5I A;  2JA6 A;  1DMS A;  5C18 A;  1TWC A;  1H5N A;  2C45 A;  1Y1V A;  2BE5 D;  4CRZ A;  1KQF A;  2JIP A;  3CZB A;  1CZ5 A;  1CR5 A;  1AW8 B;  1S3S A;  1I50 A;  5GLF A;  3GTM A;  2E7Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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