4AONB

Conformational dynamics of aspartate alpha-decarboxylase active site revealed by protein-ligand complexes: 1-methyl-l-aspartate complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
97
structure length
97
Chain Sequence
CAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Dynamics of Aspartate Alpha Decarboxylase Active Site Revealed by Protein-Ligand Complexes
rcsb
molecule keywords ASPARTATE-ALPHA-DECARBOXYLASE BETA CHAIN
molecule tags Hydrolase
source organism Escherichia coli
total genus 23
structure length 97
sequence length 97
chains with identical sequence E
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2012-03-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4aonB00
1PQFA 2E2IA 1I3QA 4QIWA 1R7RA 3QC8A 5GLFA 2JIMA 1PT0A 4KO8A 5FTLA 4GA5A 2JIOA 3O5AA 4DMRA 1Y1WA 3HU1A 3IR6A 2E2HA 2WAQA 2PMZA 4AZDA 1R9TA 3GTJA 1Y4ZA 1PYUB 3QWZA 5T5ID 1AA6A 1UHEA 4AOKB 1PPYA 5C18A 3HU3A 3OUGA 2VPYA 1E32A 5T5MD 2WB1A 1CR5A 2R92A 1VC3B 1TWFA 1IW7D 2C45A 1G8JA 1R27A 3GTQA 5FTNA 2KI8A 2NYAA 4RV0A 4D7ZB 2VUMA 5FTKA 3H0GA 5DYIA 4CS0A 2R7ZA 1CZ5A 2DMRA 1AW8B 4KDLA 3CF2A 1Y5IA 2B63A 2VPXA 1FDOA 1S3SA 2JA6A 3TIWA 1TWHA 2NVYA 2PJHB 4CRZA 3GTPA 1KQGA 3HU2A 2IV2X 4CRYG 3ML1A 1H5NA 1E5VA 3QQ8A 1PT1A 5DYGA 2V45A 2JIPA 3IR7A 4KODA 2JA5A 1TWGA 3HKZA 4GA6A 3PLXB 5C1BA 3FKIA 3TM7B 1Q16A 1TWAA 2VPZA 3QQ7A 1CZ4A 1PQHA 1QDNA 1SIWA 2E7ZA 1PQEA 2NVXA 1EU1A 4AAYA 4C2MA 1QCSA 2Y0SA 5FTJA 5FTMA 1TWCA 4KDIA 4AONB 1K83A 3GTKA 1E60A 5B6CA 1E18A 1SFOA 1Y1VA 1KQFA 3CQZA 1G8KA 2VPWA 5EPPA 2V3VA 4AYBA 2R93A 1WCMA 1UHDA 1E61A 2JIQA 1H0HA 3GTMA 1TMOA 2JIRA 3GTOA 1FDIA 1YLEA 1OGYA 2NAPA 3GTGA 1DMRA 1WLFA 2EEOB 3IR5A 4KLNA 1DMSA 2YU9A 2JA7A 3GTLA 1PYQA 3DMRA 1I50A
chains in the Genus database with same CATH superfamily
2A68D 1PQFA 2BH0A 2E2IA 1I3QA 4QIWA 1R7RA 3QC8A 5GLFA 2JIMA 1PT0A 5GLYA 3SUJA 4KO8A 2AE0X 5FTLA 1N10A 3X2PA 4GA5A 2JIOA 1ZC1A 3O5AA 4DMRA 2PJJA 3X2LA 1Y1WA 3HU1A 3IR6A 2E2HA 2WAQA 2PMZA 2HCZX 4AZDA 1R9TA 1Y4ZA 1PYUB 2A6ED 3QWZA 5T5ID 1AA6A 3GTJA 1UHEA 4AOKB 1PPYA 2KQAA 3HU3A 3OUGA 5C18A 2VPYA 1E32A 5T5MD 2WB1A 1CR5A 2R92A 1VC3B 1TWFA 5GLXA 1IW7D 2C45A 1G8JA 4FG4A 1R27A 3GTQA 5FTNA 3X2HA 2KI8A 2G5DA 2NYAA 4RV0A 4D7ZB 1YNJD 5FTKA 2VUMA 1BW4A 3H0GA 3X2KA 1HD5A 5DYIA 4CS0A 2PNWA 3D30A 3X2OA 4NOHA 2R7ZA 4L48A 1CZ5A 2DMRA 1AW8B 4KDLA 3CF2A 1BW3A 1Y5IA 2B63A 2VPXA 4AVRA 2G6GA 1FDOA 1S3SA 2JA6A 3TIWA 1TWHA 2A69D 2PJHB 2NVYA 3M3GA 4FFTA 4CRZA 2ENGA 3HU2A 1KQGA 3GTPA 2BE5D 3SUMA 2IV2X 4CRYG 3ML1A 1H5NA 3X2GA 2PICA 4JS7A 1E5VA 3QQ8A 1PT1A 5DYGA 2V45A 2O5JD 5H4UA 2JIPA 1OA9A 4FG2A 3ENGA 3IR7A 4KODA 2JA5A 3SULA 1TWGA 3DMRA 3X2JA 3HKZA 4GA6A 3PLXB 5C1BA 3FKIA 3TM7B 1Q16A 4ENGA 1TWAA 2VPZA 1OA7A 3QQ7A 1CZ4A 1PQHA 4JCWA 1QDNA 1SIWA 2E7ZA 1PQEA 4JJOA 2NVXA 1EU1A 4AAYA 4C2MA 1QCSA 2Y0SA 5FTJA 5FTMA 1TWCA 4KDIA 4AONB 1K83A 3GTKA 1YNND 1E60A 1WC2A 5B6CA 1E18A 1SFOA 2CW0D 1Y1VA 4FERA 3SUKA 3X2MA 1KQFA 1L8FA 3CQZA 1G8KA 2VPWA 5GM9A 5EPPA 2V3VA 4AYBA 2R93A 1WCMA 3X2NA 1UHDA 1E61A 3X2IA 2JIQA 1H0HA 2YUJA 3GTMA 2GAEA 1TMOA 2JIRA 3GTOA 4ZM7A 1FDIA 1YLEA 1SMYD 1ZYRD 1OGYA 2NAPA 2PI8A 3GTGA 1DMRA 1WLFA 2EEOB 3IR5A 2A6HD 1DMSA 4KLNA 2YU9A 2JA7A 3GTLA 4JP7A 4JP6A 1PYQA 3CZBA 1I50A
chains in the Genus database with same CATH topology
2A68D 1PQFA 2E2IA 1I3QA 4QIWA 1R7RA 3QC8A 5GLFA 2JIMA 1PT0A 4KO8A 2AE0X 5FTLA 4GA5A 2JIOA 1ZC1A 3O5AA 4DMRA 2PJJA 1Y1WA 3HU1A 3IR6A 2E2HA 2WAQA 2PMZA 4AZDA 1R9TA 3GTJA 1Y4ZA 1PYUB 2A6ED 3QWZA 5T5ID 1AA6A 1UHEA 4AOKB 1PPYA 5C18A 3HU3A 3OUGA 2VPYA 1E32A 5T5MD 2WB1A 1CR5A 2R92A 1VC3B 1TWFA 1IW7D 2C45A 1G8JA 1R27A 3GTQA 5FTNA 2KI8A 2G5DA 2NYAA 4RV0A 4D7ZB 1YNJD 5FTKA 2VUMA 3H0GA 5DYIA 4CS0A 2PNWA 4NOHA 2R7ZA 1CZ5A 2DMRA 1AW8B 4KDLA 3CF2A 1Y5IA 2B63A 2VPXA 2G6GA 1FDOA 1S3SA 2JA6A 3TIWA 1TWHA 2A69D 2PJHB 2NVYA 4CRZA 1KQGA 3GTPA 3HU2A 2BE5D 2IV2X 4CRYG 3ML1A 1H5NA 2PICA 1E5VA 3QQ8A 1PT1A 5DYGA 2V45A 2O5JD 2JIPA 3IR7A 4KODA 2JA5A 1TWGA 3DMRA 3HKZA 4GA6A 3PLXB 5C1BA 3FKIA 3TM7B 1Q16A 1TWAA 2VPZA 3QQ7A 1CZ4A 1PQHA 1QDNA 1SIWA 2E7ZA 1PQEA 2NVXA 1EU1A 4AAYA 4C2MA 1QCSA 2Y0SA 5FTJA 5FTMA 1TWCA 4KDIA 4AONB 1K83A 3GTKA 1YNND 1E60A 5B6CA 1E18A 1SFOA 2CW0D 1Y1VA 1KQFA 3CQZA 1G8KA 2VPWA 5EPPA 2V3VA 4AYBA 2R93A 1WCMA 1UHDA 1E61A 2JIQA 1H0HA 2YUJA 3GTMA 2GAEA 1TMOA 2JIRA 3GTOA 1FDIA 1YLEA 1SMYD 1ZYRD 1OGYA 2NAPA 2PI8A 3GTGA 1DMRA 1WLFA 2EEOB 3IR5A 2A6HD 1DMSA 4KLNA 2YU9A 2JA7A 3GTLA 1PYQA 3CZBA 1I50A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PQF A;  2E2I A;  1I3Q A;  4QIW A;  1R7R A;  3QC8 A;  5GLF A;  2JIM A;  1PT0 A;  4KO8 A;  5FTL A;  4GA5 A;  2JIO A;  3O5A A;  4DMR A;  1Y1W A;  3HU1 A;  3IR6 A;  2E2H A;  2WAQ A;  2PMZ A;  4AZD A;  1R9T A;  3GTJ A;  1Y4Z A;  1PYU B;  3QWZ A;  5T5I D;  1AA6 A;  1UHE A;  4AOK B;  1PPY A;  5C18 A;  3HU3 A;  3OUG A;  2VPY A;  1E32 A;  5T5M D;  2WB1 A;  1CR5 A;  2R92 A;  1VC3 B;  1TWF A;  1IW7 D;  2C45 A;  1G8J A;  1R27 A;  3GTQ A;  5FTN A;  2KI8 A;  2NYA A;  4RV0 A;  4D7Z B;  2VUM A;  5FTK A;  3H0G A;  5DYI A;  4CS0 A;  2R7Z A;  1CZ5 A;  2DMR A;  1AW8 B;  4KDL A;  3CF2 A;  1Y5I A;  2B63 A;  2VPX A;  1FDO A;  1S3S A;  2JA6 A;  3TIW A;  1TWH A;  2NVY A;  2PJH B;  4CRZ A;  3GTP A;  1KQG A;  3HU2 A;  2IV2 X;  4CRY G;  3ML1 A;  1H5N A;  1E5V A;  3QQ8 A;  1PT1 A;  5DYG A;  2V45 A;  2JIP A;  3IR7 A;  4KOD A;  2JA5 A;  1TWG A;  3HKZ A;  4GA6 A;  3PLX B;  5C1B A;  3FKI A;  3TM7 B;  1Q16 A;  1TWA A;  2VPZ A;  3QQ7 A;  1CZ4 A;  1PQH A;  1QDN A;  1SIW A;  2E7Z A;  1PQE A;  2NVX A;  1EU1 A;  4AAY A;  4C2M A;  1QCS A;  2Y0S A;  5FTJ A;  5FTM A;  1TWC A;  4KDI A;  4AON B;  1K83 A;  3GTK A;  1E60 A;  5B6C A;  1E18 A;  1SFO A;  1Y1V A;  1KQF A;  3CQZ A;  1G8K A;  2VPW A;  5EPP A;  2V3V A;  4AYB A;  2R93 A;  1WCM A;  1UHD A;  1E61 A;  2JIQ A;  1H0H A;  3GTM A;  1TMO A;  2JIR A;  3GTO A;  1FDI A;  1YLE A;  1OGY A;  2NAP A;  3GTG A;  1DMR A;  1WLF A;  2EEO B;  3IR5 A;  4KLN A;  1DMS A;  2YU9 A;  2JA7 A;  3GTL A;  1PYQ A;  3DMR A;  1I50 A; 
#chains in the Genus database with same CATH topology
 2A68 D;  1PQF A;  2BH0 A;  2E2I A;  1I3Q A;  4QIW A;  1R7R A;  3QC8 A;  5GLF A;  2JIM A;  1PT0 A;  5GLY A;  3SUJ A;  4KO8 A;  2AE0 X;  5FTL A;  1N10 A;  3X2P A;  4GA5 A;  2JIO A;  1ZC1 A;  3O5A A;  4DMR A;  2PJJ A;  3X2L A;  1Y1W A;  3HU1 A;  3IR6 A;  2E2H A;  2WAQ A;  2PMZ A;  2HCZ X;  4AZD A;  1R9T A;  1Y4Z A;  1PYU B;  2A6E D;  3QWZ A;  5T5I D;  1AA6 A;  3GTJ A;  1UHE A;  4AOK B;  1PPY A;  2KQA A;  3HU3 A;  3OUG A;  5C18 A;  2VPY A;  1E32 A;  5T5M D;  2WB1 A;  1CR5 A;  2R92 A;  1VC3 B;  1TWF A;  5GLX A;  1IW7 D;  2C45 A;  1G8J A;  4FG4 A;  1R27 A;  3GTQ A;  5FTN A;  3X2H A;  2KI8 A;  2G5D A;  2NYA A;  4RV0 A;  4D7Z B;  1YNJ D;  5FTK A;  2VUM A;  1BW4 A;  3H0G A;  3X2K A;  1HD5 A;  5DYI A;  4CS0 A;  2PNW A;  3D30 A;  3X2O A;  4NOH A;  2R7Z A;  4L48 A;  1CZ5 A;  2DMR A;  1AW8 B;  4KDL A;  3CF2 A;  1BW3 A;  1Y5I A;  2B63 A;  2VPX A;  4AVR A;  2G6G A;  1FDO A;  1S3S A;  2JA6 A;  3TIW A;  1TWH A;  2A69 D;  2PJH B;  2NVY A;  3M3G A;  4FFT A;  4CRZ A;  2ENG A;  3HU2 A;  1KQG A;  3GTP A;  2BE5 D;  3SUM A;  2IV2 X;  4CRY G;  3ML1 A;  1H5N A;  3X2G A;  2PIC A;  4JS7 A;  1E5V A;  3QQ8 A;  1PT1 A;  5DYG A;  2V45 A;  2O5J D;  5H4U A;  2JIP A;  1OA9 A;  4FG2 A;  3ENG A;  3IR7 A;  4KOD A;  2JA5 A;  3SUL A;  1TWG A;  3DMR A;  3X2J A;  3HKZ A;  4GA6 A;  3PLX B;  5C1B A;  3FKI A;  3TM7 B;  1Q16 A;  4ENG A;  1TWA A;  2VPZ A;  1OA7 A;  3QQ7 A;  1CZ4 A;  1PQH A;  4JCW A;  1QDN A;  1SIW A;  2E7Z A;  1PQE A;  4JJO A;  2NVX A;  1EU1 A;  4AAY A;  4C2M A;  1QCS A;  2Y0S A;  5FTJ A;  5FTM A;  1TWC A;  4KDI A;  4AON B;  1K83 A;  3GTK A;  1YNN D;  1E60 A;  1WC2 A;  5B6C A;  1E18 A;  1SFO A;  2CW0 D;  1Y1V A;  4FER A;  3SUK A;  3X2M A;  1KQF A;  1L8F A;  3CQZ A;  1G8K A;  2VPW A;  5GM9 A;  5EPP A;  2V3V A;  4AYB A;  2R93 A;  1WCM A;  3X2N A;  1UHD A;  1E61 A;  3X2I A;  2JIQ A;  1H0H A;  2YUJ A;  3GTM A;  2GAE A;  1TMO A;  2JIR A;  3GTO A;  4ZM7 A;  1FDI A;  1YLE A;  1SMY D;  1ZYR D;  1OGY A;  2NAP A;  2PI8 A;  3GTG A;  1DMR A;  1WLF A;  2EEO B;  3IR5 A;  2A6H D;  1DMS A;  4KLN A;  2YU9 A;  2JA7 A;  3GTL A;  4JP7 A;  4JP6 A;  1PYQ A;  3CZB A;  1I50 A; 
#chains in the Genus database with same CATH homology
 2A68 D;  1PQF A;  2E2I A;  1I3Q A;  4QIW A;  1R7R A;  3QC8 A;  5GLF A;  2JIM A;  1PT0 A;  4KO8 A;  2AE0 X;  5FTL A;  4GA5 A;  2JIO A;  1ZC1 A;  3O5A A;  4DMR A;  2PJJ A;  1Y1W A;  3HU1 A;  3IR6 A;  2E2H A;  2WAQ A;  2PMZ A;  4AZD A;  1R9T A;  3GTJ A;  1Y4Z A;  1PYU B;  2A6E D;  3QWZ A;  5T5I D;  1AA6 A;  1UHE A;  4AOK B;  1PPY A;  5C18 A;  3HU3 A;  3OUG A;  2VPY A;  1E32 A;  5T5M D;  2WB1 A;  1CR5 A;  2R92 A;  1VC3 B;  1TWF A;  1IW7 D;  2C45 A;  1G8J A;  1R27 A;  3GTQ A;  5FTN A;  2KI8 A;  2G5D A;  2NYA A;  4RV0 A;  4D7Z B;  1YNJ D;  5FTK A;  2VUM A;  3H0G A;  5DYI A;  4CS0 A;  2PNW A;  4NOH A;  2R7Z A;  1CZ5 A;  2DMR A;  1AW8 B;  4KDL A;  3CF2 A;  1Y5I A;  2B63 A;  2VPX A;  2G6G A;  1FDO A;  1S3S A;  2JA6 A;  3TIW A;  1TWH A;  2A69 D;  2PJH B;  2NVY A;  4CRZ A;  1KQG A;  3GTP A;  3HU2 A;  2BE5 D;  2IV2 X;  4CRY G;  3ML1 A;  1H5N A;  2PIC A;  1E5V A;  3QQ8 A;  1PT1 A;  5DYG A;  2V45 A;  2O5J D;  2JIP A;  3IR7 A;  4KOD A;  2JA5 A;  1TWG A;  3DMR A;  3HKZ A;  4GA6 A;  3PLX B;  5C1B A;  3FKI A;  3TM7 B;  1Q16 A;  1TWA A;  2VPZ A;  3QQ7 A;  1CZ4 A;  1PQH A;  1QDN A;  1SIW A;  2E7Z A;  1PQE A;  2NVX A;  1EU1 A;  4AAY A;  4C2M A;  1QCS A;  2Y0S A;  5FTJ A;  5FTM A;  1TWC A;  4KDI A;  4AON B;  1K83 A;  3GTK A;  1YNN D;  1E60 A;  5B6C A;  1E18 A;  1SFO A;  2CW0 D;  1Y1V A;  1KQF A;  3CQZ A;  1G8K A;  2VPW A;  5EPP A;  2V3V A;  4AYB A;  2R93 A;  1WCM A;  1UHD A;  1E61 A;  2JIQ A;  1H0H A;  2YUJ A;  3GTM A;  2GAE A;  1TMO A;  2JIR A;  3GTO A;  1FDI A;  1YLE A;  1SMY D;  1ZYR D;  1OGY A;  2NAP A;  2PI8 A;  3GTG A;  1DMR A;  1WLF A;  2EEO B;  3IR5 A;  2A6H D;  1DMS A;  4KLN A;  2YU9 A;  2JA7 A;  3GTL A;  1PYQ A;  3CZB A;  1I50 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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