1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
molecule keywords Aspartate 1-decarboxylase
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
2WB1A 2E2IA 1CZ4A 4AOKB 1Y4ZA 1PQFA 1KQGA 3CF2A 4KDIA 4AZDA 4AONB 4CS0A 2R93A 1Y1VA 4RV0A 4AYBA 1PYQA 1WCMA 2YU9A 2B63A 5C1BA 2KI8A 3TIWA 1SFOA 1TWAA 1FDOA 2JIRA 2IV2X 3GTMA 4KO8A 1G8JA 5B6CA 4AAYA 4KDLA 1DMRA 1FDIA 5C18A 2E7ZA 1Q16A 1UHDA 1WLFA 1E5VA 2R7ZA 2PMZA 5DYIA 2NAPA 2JIOA 3GTKA 1QCSA 1H5NA 1E32A 1SIWA 4D7ZB 1TMOA 2PJHB 3ML1A 2NVXA 5T5ID 1E18A 1PT1A 1AW8B 2EEOB 2VUMA 1CR5A 2JA5A 3QQ8A 2VPXA 1IW7D 1VC3B 5FTNA 3DMRA 1G8KA 1OGYA 2V45A 4KLNA 1TWFA 4C2MA 1R7RA 3GTLA 2JIPA 3GTOA 1PPYA 1PQHA 3HU3A 3QWZA 1I3QA 2E2HA 1KQFA 3FKIA 5GLFA 5FTLA 1I50A 2C45A 2Y0SA 5T5MD 1Y5IA 1QDNA 2NYAA 3IR6A 3GTJA 1DMSA 2JIQA 2V3VA 3IR5A 1TWGA 5FTJA 2R92A 1S3SA 1EU1A 1R27A 3GTGA 1E61A 1E60A 2VPWA 1UHEA 5DYGA 3HKZA 1PT0A 2VPZA 1Y1WA 1K83A 4GA5A 4GA6A 1YLEA 1PQEA 5FTMA 4CRYG 1TWHA 2VPYA 2JA7A 2JA6A 3CQZA 3QQ7A 1PYUB 2NVYA 3O5AA 5FTKA 3HU2A 1AA6A 3GTPA 5EPPA 4KODA 3QC8A 1CZ5A 3IR7A 3TM7B 1R9TA 4QIWA 2DMRA 1TWCA 4DMRA 3GTQA 3PLXB 1H0HA 4CRZA 2WAQA 3HU1A 2JIMA 3OUGA 3H0GA
chains in the Genus database with same CATH superfamily
2WB1A 2E2IA 5GM9A 1CZ4A 3SULA 3X2PA 4AOKB 1Y4ZA 1PQFA 1KQGA 3CF2A 4KDIA 4AZDA 2YUJA 3X2KA 4AONB 4CS0A 4FFTA 2CW0D 2R93A 1Y1VA 4RV0A 2GAEA 4AVRA 4AYBA 1PYQA 1WCMA 4L48A 3SUMA 3X2GA 2YU9A 2B63A 5C1BA 2KI8A 4JJOA 3TIWA 1SFOA 1SMYD 4NOHA 1TWAA 2JIRA 1FDOA 2IV2X 3GTMA 4KO8A 1G8JA 3M3GA 5B6CA 4AAYA 2G6GA 4KDLA 1DMRA 1FDIA 3D30A 5C18A 2E7ZA 3X2LA 1Q16A 1YNJD 1UHDA 1WLFA 1E5VA 2R7ZA 5GLYA 2PMZA 5DYIA 4ZM7A 2NAPA 2JIOA 3GTKA 1HD5A 1QCSA 1H5NA 1BW3A 4FERA 1E32A 1SIWA 4D7ZB 1TMOA 2PJHB 3ML1A 2NVXA 2HCZX 5T5ID 1E18A 3X2HA 1PT1A 1AW8B 2A6HD 2EEOB 2VUMA 1CR5A 2JA5A 3QQ8A 2PI8A 3SUJA 3X2MA 1L8FA 2VPXA 1IW7D 1VC3B 2BE5D 3DMRA 1G8KA 1OGYA 2V45A 1ZC1A 1TWFA 4KLNA 5FTNA 4C2MA 1R7RA 4JCWA 2A68D 1N10A 3GTLA 2JIPA 3GTOA 1PPYA 4JP7A 1PQHA 3HU3A 3QWZA 1YNND 2PICA 1I3QA 2E2HA 1KQFA 3FKIA 5GLFA 5FTLA 1I50A 2C45A 2Y0SA 1OA7A 5T5MD 4JS7A 1Y5IA 2A69D 1QDNA 2NYAA 3IR6A 3GTJA 2A6ED 3X2JA 2ENGA 3CZBA 2KQAA 2AE0X 1DMSA 2O5JD 2V3VA 3IR5A 1TWGA 5FTJA 3H0GA 1S3SA 1WC2A 2R92A 1EU1A 1R27A 3GTGA 1E61A 1BW4A 1E60A 2VPWA 1UHEA 5DYGA 3HKZA 1PT0A 2VPZA 1Y1WA 1K83A 4GA5A 3ENGA 5GLXA 4FG2A 4GA6A 4ENGA 2PJJA 1YLEA 1PQEA 5FTMA 4CRYG 1TWHA 2VPYA 2JA7A 2PNWA 2JA6A 5H4UA 3SUKA 4FG4A 1OA9A 3CQZA 3QQ7A 1PYUB 2NVYA 3O5AA 5FTKA 3HU2A 1AA6A 3GTPA 5EPPA 2G5DA 4KODA 3QC8A 1CZ5A 3IR7A 2BH0A 3TM7B 1R9TA 4QIWA 2DMRA 1ZYRD 1TWCA 3X2IA 4DMRA 3GTQA 3PLXB 3X2NA 1H0HA 4JP6A 2WAQA 4CRZA 3HU1A 2JIMA 3X2OA 3OUGA 2JIQA
chains in the Genus database with same CATH topology
2WB1A 2E2IA 1CZ4A 4AOKB 1Y4ZA 1PQFA 1KQGA 3CF2A 4KDIA 4AZDA 2YUJA 4AONB 4CS0A 2CW0D 2R93A 1Y1VA 4RV0A 2GAEA 4AYBA 1PYQA 1WCMA 2YU9A 2B63A 5C1BA 2KI8A 3TIWA 1SFOA 1SMYD 4NOHA 1TWAA 2JIRA 1FDOA 2IV2X 3GTMA 4KO8A 1G8JA 5B6CA 4AAYA 2G6GA 4KDLA 1DMRA 1FDIA 5C18A 2E7ZA 1Q16A 1YNJD 1UHDA 1WLFA 1E5VA 2R7ZA 2PMZA 5DYIA 2NAPA 2JIOA 3GTKA 1QCSA 1H5NA 1E32A 1SIWA 4D7ZB 1TMOA 2PJHB 3ML1A 2NVXA 5T5ID 1E18A 1PT1A 1AW8B 2A6HD 2EEOB 2VUMA 1CR5A 2JA5A 3QQ8A 2PI8A 2VPXA 1IW7D 1VC3B 2BE5D 3DMRA 1G8KA 1OGYA 2V45A 1ZC1A 1TWFA 4KLNA 5FTNA 4C2MA 1R7RA 2A68D 3GTLA 2JIPA 3GTOA 1PPYA 1PQHA 3HU3A 3QWZA 1YNND 2PICA 1I3QA 2E2HA 1KQFA 3FKIA 5GLFA 5FTLA 1I50A 2C45A 2Y0SA 5T5MD 1Y5IA 2A69D 1QDNA 2NYAA 3IR6A 3GTJA 2A6ED 3CZBA 2AE0X 1DMSA 2O5JD 2V3VA 3IR5A 1TWGA 5FTJA 3H0GA 1S3SA 2R92A 1EU1A 1R27A 3GTGA 1E61A 1E60A 2VPWA 1UHEA 5DYGA 3HKZA 1PT0A 2VPZA 1Y1WA 1K83A 4GA5A 4GA6A 2PJJA 1YLEA 1PQEA 5FTMA 4CRYG 1TWHA 2VPYA 2JA7A 2PNWA 2JA6A 3CQZA 3QQ7A 1PYUB 2NVYA 3O5AA 5FTKA 3HU2A 1AA6A 3GTPA 5EPPA 2G5DA 4KODA 3QC8A 1CZ5A 3IR7A 3TM7B 1R9TA 4QIWA 2DMRA 1ZYRD 1TWCA 4DMRA 3GTQA 3PLXB 1H0HA 4CRZA 2WAQA 3HU1A 2JIMA 3OUGA 2JIQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WB1 A;  2E2I A;  1CZ4 A;  4AOK B;  1Y4Z A;  1PQF A;  1KQG A;  3CF2 A;  4KDI A;  4AZD A;  4AON B;  4CS0 A;  2R93 A;  1Y1V A;  4RV0 A;  4AYB A;  1PYQ A;  1WCM A;  2YU9 A;  2B63 A;  5C1B A;  2KI8 A;  3TIW A;  1SFO A;  1TWA A;  1FDO A;  2JIR A;  2IV2 X;  3GTM A;  4KO8 A;  1G8J A;  5B6C A;  4AAY A;  4KDL A;  1DMR A;  1FDI A;  5C18 A;  2E7Z A;  1Q16 A;  1UHD A;  1WLF A;  1E5V A;  2R7Z A;  2PMZ A;  5DYI A;  2NAP A;  2JIO A;  3GTK A;  1QCS A;  1H5N A;  1E32 A;  1SIW A;  4D7Z B;  1TMO A;  2PJH B;  3ML1 A;  2NVX A;  5T5I D;  1E18 A;  1PT1 A;  1AW8 B;  2EEO B;  2VUM A;  1CR5 A;  2JA5 A;  3QQ8 A;  2VPX A;  1IW7 D;  1VC3 B;  5FTN A;  3DMR A;  1G8K A;  1OGY A;  2V45 A;  4KLN A;  1TWF A;  4C2M A;  1R7R A;  3GTL A;  2JIP A;  3GTO A;  1PPY A;  1PQH A;  3HU3 A;  3QWZ A;  1I3Q A;  2E2H A;  1KQF A;  3FKI A;  5GLF A;  5FTL A;  1I50 A;  2C45 A;  2Y0S A;  5T5M D;  1Y5I A;  1QDN A;  2NYA A;  3IR6 A;  3GTJ A;  1DMS A;  2JIQ A;  2V3V A;  3IR5 A;  1TWG A;  5FTJ A;  2R92 A;  1S3S A;  1EU1 A;  1R27 A;  3GTG A;  1E61 A;  1E60 A;  2VPW A;  1UHE A;  5DYG A;  3HKZ A;  1PT0 A;  2VPZ A;  1Y1W A;  1K83 A;  4GA5 A;  4GA6 A;  1YLE A;  1PQE A;  5FTM A;  4CRY G;  1TWH A;  2VPY A;  2JA7 A;  2JA6 A;  3CQZ A;  3QQ7 A;  1PYU B;  2NVY A;  3O5A A;  5FTK A;  3HU2 A;  1AA6 A;  3GTP A;  5EPP A;  4KOD A;  3QC8 A;  1CZ5 A;  3IR7 A;  3TM7 B;  1R9T A;  4QIW A;  2DMR A;  1TWC A;  4DMR A;  3GTQ A;  3PLX B;  1H0H A;  4CRZ A;  2WAQ A;  3HU1 A;  2JIM A;  3OUG A;  3H0G A; 
#chains in the Genus database with same CATH topology
 2WB1 A;  2E2I A;  5GM9 A;  1CZ4 A;  3SUL A;  3X2P A;  4AOK B;  1Y4Z A;  1PQF A;  1KQG A;  3CF2 A;  4KDI A;  4AZD A;  2YUJ A;  3X2K A;  4AON B;  4CS0 A;  4FFT A;  2CW0 D;  2R93 A;  1Y1V A;  4RV0 A;  2GAE A;  4AVR A;  4AYB A;  1PYQ A;  1WCM A;  4L48 A;  3SUM A;  3X2G A;  2YU9 A;  2B63 A;  5C1B A;  2KI8 A;  4JJO A;  3TIW A;  1SFO A;  1SMY D;  4NOH A;  1TWA A;  2JIR A;  1FDO A;  2IV2 X;  3GTM A;  4KO8 A;  1G8J A;  3M3G A;  5B6C A;  4AAY A;  2G6G A;  4KDL A;  1DMR A;  1FDI A;  3D30 A;  5C18 A;  2E7Z A;  3X2L A;  1Q16 A;  1YNJ D;  1UHD A;  1WLF A;  1E5V A;  2R7Z A;  5GLY A;  2PMZ A;  5DYI A;  4ZM7 A;  2NAP A;  2JIO A;  3GTK A;  1HD5 A;  1QCS A;  1H5N A;  1BW3 A;  4FER A;  1E32 A;  1SIW A;  4D7Z B;  1TMO A;  2PJH B;  3ML1 A;  2NVX A;  2HCZ X;  5T5I D;  1E18 A;  3X2H A;  1PT1 A;  1AW8 B;  2A6H D;  2EEO B;  2VUM A;  1CR5 A;  2JA5 A;  3QQ8 A;  2PI8 A;  3SUJ A;  3X2M A;  1L8F A;  2VPX A;  1IW7 D;  1VC3 B;  2BE5 D;  3DMR A;  1G8K A;  1OGY A;  2V45 A;  1ZC1 A;  1TWF A;  4KLN A;  5FTN A;  4C2M A;  1R7R A;  4JCW A;  2A68 D;  1N10 A;  3GTL A;  2JIP A;  3GTO A;  1PPY A;  4JP7 A;  1PQH A;  3HU3 A;  3QWZ A;  1YNN D;  2PIC A;  1I3Q A;  2E2H A;  1KQF A;  3FKI A;  5GLF A;  5FTL A;  1I50 A;  2C45 A;  2Y0S A;  1OA7 A;  5T5M D;  4JS7 A;  1Y5I A;  2A69 D;  1QDN A;  2NYA A;  3IR6 A;  3GTJ A;  2A6E D;  3X2J A;  2ENG A;  3CZB A;  2KQA A;  2AE0 X;  1DMS A;  2O5J D;  2V3V A;  3IR5 A;  1TWG A;  5FTJ A;  3H0G A;  1S3S A;  1WC2 A;  2R92 A;  1EU1 A;  1R27 A;  3GTG A;  1E61 A;  1BW4 A;  1E60 A;  2VPW A;  1UHE A;  5DYG A;  3HKZ A;  1PT0 A;  2VPZ A;  1Y1W A;  1K83 A;  4GA5 A;  3ENG A;  5GLX A;  4FG2 A;  4GA6 A;  4ENG A;  2PJJ A;  1YLE A;  1PQE A;  5FTM A;  4CRY G;  1TWH A;  2VPY A;  2JA7 A;  2PNW A;  2JA6 A;  5H4U A;  3SUK A;  4FG4 A;  1OA9 A;  3CQZ A;  3QQ7 A;  1PYU B;  2NVY A;  3O5A A;  5FTK A;  3HU2 A;  1AA6 A;  3GTP A;  5EPP A;  2G5D A;  4KOD A;  3QC8 A;  1CZ5 A;  3IR7 A;  2BH0 A;  3TM7 B;  1R9T A;  4QIW A;  2DMR A;  1ZYR D;  1TWC A;  3X2I A;  4DMR A;  3GTQ A;  3PLX B;  3X2N A;  1H0H A;  4JP6 A;  2WAQ A;  4CRZ A;  3HU1 A;  2JIM A;  3X2O A;  3OUG A;  2JIQ A; 
#chains in the Genus database with same CATH homology
 2WB1 A;  2E2I A;  1CZ4 A;  4AOK B;  1Y4Z A;  1PQF A;  1KQG A;  3CF2 A;  4KDI A;  4AZD A;  2YUJ A;  4AON B;  4CS0 A;  2CW0 D;  2R93 A;  1Y1V A;  4RV0 A;  2GAE A;  4AYB A;  1PYQ A;  1WCM A;  2YU9 A;  2B63 A;  5C1B A;  2KI8 A;  3TIW A;  1SFO A;  1SMY D;  4NOH A;  1TWA A;  2JIR A;  1FDO A;  2IV2 X;  3GTM A;  4KO8 A;  1G8J A;  5B6C A;  4AAY A;  2G6G A;  4KDL A;  1DMR A;  1FDI A;  5C18 A;  2E7Z A;  1Q16 A;  1YNJ D;  1UHD A;  1WLF A;  1E5V A;  2R7Z A;  2PMZ A;  5DYI A;  2NAP A;  2JIO A;  3GTK A;  1QCS A;  1H5N A;  1E32 A;  1SIW A;  4D7Z B;  1TMO A;  2PJH B;  3ML1 A;  2NVX A;  5T5I D;  1E18 A;  1PT1 A;  1AW8 B;  2A6H D;  2EEO B;  2VUM A;  1CR5 A;  2JA5 A;  3QQ8 A;  2PI8 A;  2VPX A;  1IW7 D;  1VC3 B;  2BE5 D;  3DMR A;  1G8K A;  1OGY A;  2V45 A;  1ZC1 A;  1TWF A;  4KLN A;  5FTN A;  4C2M A;  1R7R A;  2A68 D;  3GTL A;  2JIP A;  3GTO A;  1PPY A;  1PQH A;  3HU3 A;  3QWZ A;  1YNN D;  2PIC A;  1I3Q A;  2E2H A;  1KQF A;  3FKI A;  5GLF A;  5FTL A;  1I50 A;  2C45 A;  2Y0S A;  5T5M D;  1Y5I A;  2A69 D;  1QDN A;  2NYA A;  3IR6 A;  3GTJ A;  2A6E D;  3CZB A;  2AE0 X;  1DMS A;  2O5J D;  2V3V A;  3IR5 A;  1TWG A;  5FTJ A;  3H0G A;  1S3S A;  2R92 A;  1EU1 A;  1R27 A;  3GTG A;  1E61 A;  1E60 A;  2VPW A;  1UHE A;  5DYG A;  3HKZ A;  1PT0 A;  2VPZ A;  1Y1W A;  1K83 A;  4GA5 A;  4GA6 A;  2PJJ A;  1YLE A;  1PQE A;  5FTM A;  4CRY G;  1TWH A;  2VPY A;  2JA7 A;  2PNW A;  2JA6 A;  3CQZ A;  3QQ7 A;  1PYU B;  2NVY A;  3O5A A;  5FTK A;  3HU2 A;  1AA6 A;  3GTP A;  5EPP A;  2G5D A;  4KOD A;  3QC8 A;  1CZ5 A;  3IR7 A;  3TM7 B;  1R9T A;  4QIW A;  2DMR A;  1ZYR D;  1TWC A;  4DMR A;  3GTQ A;  3PLX B;  1H0H A;  4CRZ A;  2WAQ A;  3HU1 A;  2JIM A;  3OUG A;  2JIQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...