1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Lyase
molecule keywords Aspartate 1-decarboxylase
publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
source organism Escherichia coli
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
2JIRA 1Y1WA 1SIWA 1CZ5A 4RV0A 2VPYA 2JIPA 3CQZA 4CS0A 4KLNA 4AAYA 1H5NA 1PYQA 2KI8A 3OUGA 3CF2A 3ML1A 4AONB 1K83A 3GTKA 1CZ4A 1VC3B 2YU9A 1QDNA 1TWAA 4C2MA 5EPPA 3GTPA 1R27A 2B63A 1Y4ZA 1E61A 2EEOB 2VPZA 4AYBA 2JA5A 3TIWA 3PLXB 1YLEA 2E7ZA 5B6CA 1IW7D 3GTJA 4QIWA 3O5AA 1E60A 1WCMA 1Y1VA 5T5MD 4GA5A 4GA6A 2JIMA 3HU3A 3DMRA 3QWZA 3TM7B 1Q16A 5T5ID 3QQ8A 2C45A 1PQEA 2VPXA 2DMRA 2JIOA 1DMSA 3GTLA 3GTOA 5C1BA 1UHEA 2JA7A 1EU1A 1PT0A 1G8KA 1I3QA 3HU2A 1H0HA 5FTJA 5C18A 2V45A 1TMOA 1WLFA 1FDIA 2R92A 1FDOA 1AW8B 3H0GA 4KODA 1PQFA 3IR5A 3IR7A 2IV2X 1PPYA 2NAPA 3QQ7A 1UHDA 2JA6A 1TWFA 3GTGA 3QC8A 4DMRA 4CRYG 5FTLA 2E2HA 1TWCA 3IR6A 2PMZA 2Y0SA 5DYIA 5FTNA 4D7ZB 2E2IA 3GTQA 3HKZA 1OGYA 4AOKB 4CRZA 4AZDA 3FKIA 2VPWA 2R7ZA 1PQHA 1E5VA 2PJHB 4KO8A 1G8JA 5DYGA 1PYUB 2VUMA 2NVXA 3HU1A 1R9TA 1CR5A 3GTMA 1PT1A 1I50A 1Y5IA 1E32A 2JIQA 1E18A 1R7RA 1QCSA 1S3SA 4KDLA 5FTMA 5FTKA 2V3VA 1KQFA 4KDIA 1TWHA 2R93A 2NVYA 2WB1A 1SFOA 5GLFA 1TWGA 1KQGA 2NYAA 1DMRA 1AA6A 2WAQA
chains in the Genus database with same CATH superfamily
2JIRA 1Y1WA 1SIWA 2PNWA 3X2KA 1CZ5A 4FFTA 5GM9A 4RV0A 2VPYA 2JIPA 5H4UA 3CQZA 4L48A 5GLYA 4CS0A 4KLNA 4AAYA 3SULA 1H5NA 1PYQA 2KI8A 3OUGA 3CF2A 3ML1A 4AONB 2PICA 1K83A 1CZ4A 3GTKA 1VC3B 2YU9A 1QDNA 1TWAA 4C2MA 5EPPA 3GTPA 1R27A 2B63A 1Y4ZA 1E61A 2EEOB 2A68D 2BE5D 2VPZA 4AYBA 2A69D 3M3GA 2JA5A 3TIWA 4FERA 3PLXB 1YLEA 2E7ZA 3D30A 5B6CA 1IW7D 3X2MA 3GTJA 4QIWA 3O5AA 2G6GA 4JJOA 1E60A 1WC2A 1WCMA 1Y1VA 5T5MD 4GA5A 4GA6A 4JP7A 2G5DA 2JIMA 3HU3A 3DMRA 3QWZA 3X2PA 4FG4A 1BW4A 3TM7B 1Q16A 5T5ID 1BW3A 3QQ8A 2C45A 1PQEA 2VPXA 2DMRA 2JIOA 1DMSA 3GTLA 3GTOA 2O5JD 5C1BA 1UHEA 1OA9A 2JA7A 2A6HD 4ENGA 3X2LA 1EU1A 1PT0A 1G8KA 4JP6A 2YUJA 1I3QA 4JS7A 3X2NA 2A6ED 3HU2A 1H0HA 2PI8A 5FTJA 5C18A 2V45A 1TMOA 2CW0D 1SMYD 1ZYRD 4JCWA 1WLFA 1FDIA 2R92A 1FDOA 1AW8B 3H0GA 4KODA 1PQFA 3IR5A 2GAEA 3IR7A 2IV2X 1PPYA 2BH0A 2NAPA 3QQ7A 1UHDA 2JA6A 1TWFA 3GTGA 1YNJD 3QC8A 4DMRA 4CRYG 5FTLA 1HD5A 2E2HA 2AE0X 3X2IA 1TWCA 3IR6A 2PMZA 1ZC1A 2Y0SA 5DYIA 5FTNA 4D7ZB 3GTQA 3HKZA 1OGYA 4AOKB 2E2IA 4CRZA 4AZDA 1YNND 3SUJA 3X2GA 4ZM7A 3FKIA 2VPWA 2R7ZA 1PQHA 1E5VA 2PJHB 4KO8A 1G8JA 3X2JA 5DYGA 1PYUB 1N10A 2VUMA 4FG2A 1OA7A 3ENGA 2NVXA 3HU1A 3CZBA 1R9TA 1CR5A 3GTMA 1PT1A 2ENGA 2HCZX 4AVRA 1I50A 1Y5IA 1E32A 2JIQA 1E18A 1R7RA 1QCSA 1S3SA 4KDLA 5FTMA 4NOHA 5FTKA 2V3VA 3SUMA 2KQAA 5GLXA 1KQFA 4KDIA 1TWHA 3X2HA 2NVYA 2WB1A 3SUKA 1SFOA 2R93A 5GLFA 1TWGA 1KQGA 2NYAA 1DMRA 2PJJA 1AA6A 1L8FA 2WAQA 3X2OA
chains in the Genus database with same CATH topology
2JIRA 1Y1WA 1SIWA 2PNWA 1CZ5A 4RV0A 2VPYA 2JIPA 3CQZA 4CS0A 4KLNA 4AAYA 1H5NA 1PYQA 2KI8A 3OUGA 3CF2A 3ML1A 4AONB 2PICA 1K83A 1CZ4A 3GTKA 1VC3B 2YU9A 1QDNA 1TWAA 4C2MA 5EPPA 3GTPA 1R27A 2B63A 1Y4ZA 1E61A 2EEOB 2A68D 2BE5D 2VPZA 4AYBA 2A69D 2JA5A 3TIWA 3PLXB 1YLEA 2E7ZA 5B6CA 1IW7D 3GTJA 4QIWA 3O5AA 2G6GA 1E60A 1WCMA 1Y1VA 5T5MD 4GA5A 4GA6A 2G5DA 2JIMA 3HU3A 3DMRA 3QWZA 3TM7B 1Q16A 5T5ID 3QQ8A 2C45A 1PQEA 2VPXA 2DMRA 2JIOA 1DMSA 3GTLA 3GTOA 2O5JD 5C1BA 1UHEA 2JA7A 2A6HD 1EU1A 1PT0A 1G8KA 1I3QA 2YUJA 2A6ED 3HU2A 1H0HA 2PI8A 5FTJA 5C18A 2V45A 1TMOA 2CW0D 1SMYD 1ZYRD 1WLFA 1FDIA 2R92A 1FDOA 1AW8B 3H0GA 4KODA 1PQFA 3IR5A 2GAEA 3IR7A 2IV2X 1PPYA 2NAPA 3QQ7A 1UHDA 2JA6A 1TWFA 3GTGA 1YNJD 3QC8A 4DMRA 4CRYG 5FTLA 2E2HA 2AE0X 1TWCA 3IR6A 2PMZA 1ZC1A 2Y0SA 5DYIA 5FTNA 4D7ZB 3GTQA 3HKZA 1OGYA 4AOKB 2E2IA 4CRZA 4AZDA 1YNND 3FKIA 2VPWA 2R7ZA 1PQHA 1E5VA 2PJHB 4KO8A 1G8JA 5DYGA 1PYUB 2VUMA 2NVXA 3HU1A 3CZBA 1R9TA 1CR5A 3GTMA 1PT1A 1I50A 1Y5IA 1E32A 2JIQA 1E18A 1R7RA 1QCSA 1S3SA 4KDLA 5FTMA 4NOHA 5FTKA 2V3VA 1KQFA 4KDIA 1TWHA 2R93A 2NVYA 2WB1A 1SFOA 5GLFA 1TWGA 1KQGA 2NYAA 1DMRA 2PJJA 1AA6A 2WAQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JIR A;  1Y1W A;  1SIW A;  1CZ5 A;  4RV0 A;  2VPY A;  2JIP A;  3CQZ A;  4CS0 A;  4KLN A;  4AAY A;  1H5N A;  1PYQ A;  2KI8 A;  3OUG A;  3CF2 A;  3ML1 A;  4AON B;  1K83 A;  3GTK A;  1CZ4 A;  1VC3 B;  2YU9 A;  1QDN A;  1TWA A;  4C2M A;  5EPP A;  3GTP A;  1R27 A;  2B63 A;  1Y4Z A;  1E61 A;  2EEO B;  2VPZ A;  4AYB A;  2JA5 A;  3TIW A;  3PLX B;  1YLE A;  2E7Z A;  5B6C A;  1IW7 D;  3GTJ A;  4QIW A;  3O5A A;  1E60 A;  1WCM A;  1Y1V A;  5T5M D;  4GA5 A;  4GA6 A;  2JIM A;  3HU3 A;  3DMR A;  3QWZ A;  3TM7 B;  1Q16 A;  5T5I D;  3QQ8 A;  2C45 A;  1PQE A;  2VPX A;  2DMR A;  2JIO A;  1DMS A;  3GTL A;  3GTO A;  5C1B A;  1UHE A;  2JA7 A;  1EU1 A;  1PT0 A;  1G8K A;  1I3Q A;  3HU2 A;  1H0H A;  5FTJ A;  5C18 A;  2V45 A;  1TMO A;  1WLF A;  1FDI A;  2R92 A;  1FDO A;  1AW8 B;  3H0G A;  4KOD A;  1PQF A;  3IR5 A;  3IR7 A;  2IV2 X;  1PPY A;  2NAP A;  3QQ7 A;  1UHD A;  2JA6 A;  1TWF A;  3GTG A;  3QC8 A;  4DMR A;  4CRY G;  5FTL A;  2E2H A;  1TWC A;  3IR6 A;  2PMZ A;  2Y0S A;  5DYI A;  5FTN A;  4D7Z B;  2E2I A;  3GTQ A;  3HKZ A;  1OGY A;  4AOK B;  4CRZ A;  4AZD A;  3FKI A;  2VPW A;  2R7Z A;  1PQH A;  1E5V A;  2PJH B;  4KO8 A;  1G8J A;  5DYG A;  1PYU B;  2VUM A;  2NVX A;  3HU1 A;  1R9T A;  1CR5 A;  3GTM A;  1PT1 A;  1I50 A;  1Y5I A;  1E32 A;  2JIQ A;  1E18 A;  1R7R A;  1QCS A;  1S3S A;  4KDL A;  5FTM A;  5FTK A;  2V3V A;  1KQF A;  4KDI A;  1TWH A;  2R93 A;  2NVY A;  2WB1 A;  1SFO A;  5GLF A;  1TWG A;  1KQG A;  2NYA A;  1DMR A;  1AA6 A;  2WAQ A; 
#chains in the Genus database with same CATH topology
 2JIR A;  1Y1W A;  1SIW A;  2PNW A;  3X2K A;  1CZ5 A;  4FFT A;  5GM9 A;  4RV0 A;  2VPY A;  2JIP A;  5H4U A;  3CQZ A;  4L48 A;  5GLY A;  4CS0 A;  4KLN A;  4AAY A;  3SUL A;  1H5N A;  1PYQ A;  2KI8 A;  3OUG A;  3CF2 A;  3ML1 A;  4AON B;  2PIC A;  1K83 A;  1CZ4 A;  3GTK A;  1VC3 B;  2YU9 A;  1QDN A;  1TWA A;  4C2M A;  5EPP A;  3GTP A;  1R27 A;  2B63 A;  1Y4Z A;  1E61 A;  2EEO B;  2A68 D;  2BE5 D;  2VPZ A;  4AYB A;  2A69 D;  3M3G A;  2JA5 A;  3TIW A;  4FER A;  3PLX B;  1YLE A;  2E7Z A;  3D30 A;  5B6C A;  1IW7 D;  3X2M A;  3GTJ A;  4QIW A;  3O5A A;  2G6G A;  4JJO A;  1E60 A;  1WC2 A;  1WCM A;  1Y1V A;  5T5M D;  4GA5 A;  4GA6 A;  4JP7 A;  2G5D A;  2JIM A;  3HU3 A;  3DMR A;  3QWZ A;  3X2P A;  4FG4 A;  1BW4 A;  3TM7 B;  1Q16 A;  5T5I D;  1BW3 A;  3QQ8 A;  2C45 A;  1PQE A;  2VPX A;  2DMR A;  2JIO A;  1DMS A;  3GTL A;  3GTO A;  2O5J D;  5C1B A;  1UHE A;  1OA9 A;  2JA7 A;  2A6H D;  4ENG A;  3X2L A;  1EU1 A;  1PT0 A;  1G8K A;  4JP6 A;  2YUJ A;  1I3Q A;  4JS7 A;  3X2N A;  2A6E D;  3HU2 A;  1H0H A;  2PI8 A;  5FTJ A;  5C18 A;  2V45 A;  1TMO A;  2CW0 D;  1SMY D;  1ZYR D;  4JCW A;  1WLF A;  1FDI A;  2R92 A;  1FDO A;  1AW8 B;  3H0G A;  4KOD A;  1PQF A;  3IR5 A;  2GAE A;  3IR7 A;  2IV2 X;  1PPY A;  2BH0 A;  2NAP A;  3QQ7 A;  1UHD A;  2JA6 A;  1TWF A;  3GTG A;  1YNJ D;  3QC8 A;  4DMR A;  4CRY G;  5FTL A;  1HD5 A;  2E2H A;  2AE0 X;  3X2I A;  1TWC A;  3IR6 A;  2PMZ A;  1ZC1 A;  2Y0S A;  5DYI A;  5FTN A;  4D7Z B;  3GTQ A;  3HKZ A;  1OGY A;  4AOK B;  2E2I A;  4CRZ A;  4AZD A;  1YNN D;  3SUJ A;  3X2G A;  4ZM7 A;  3FKI A;  2VPW A;  2R7Z A;  1PQH A;  1E5V A;  2PJH B;  4KO8 A;  1G8J A;  3X2J A;  5DYG A;  1PYU B;  1N10 A;  2VUM A;  4FG2 A;  1OA7 A;  3ENG A;  2NVX A;  3HU1 A;  3CZB A;  1R9T A;  1CR5 A;  3GTM A;  1PT1 A;  2ENG A;  2HCZ X;  4AVR A;  1I50 A;  1Y5I A;  1E32 A;  2JIQ A;  1E18 A;  1R7R A;  1QCS A;  1S3S A;  4KDL A;  5FTM A;  4NOH A;  5FTK A;  2V3V A;  3SUM A;  2KQA A;  5GLX A;  1KQF A;  4KDI A;  1TWH A;  3X2H A;  2NVY A;  2WB1 A;  3SUK A;  1SFO A;  2R93 A;  5GLF A;  1TWG A;  1KQG A;  2NYA A;  1DMR A;  2PJJ A;  1AA6 A;  1L8F A;  2WAQ A;  3X2O A; 
#chains in the Genus database with same CATH homology
 2JIR A;  1Y1W A;  1SIW A;  2PNW A;  1CZ5 A;  4RV0 A;  2VPY A;  2JIP A;  3CQZ A;  4CS0 A;  4KLN A;  4AAY A;  1H5N A;  1PYQ A;  2KI8 A;  3OUG A;  3CF2 A;  3ML1 A;  4AON B;  2PIC A;  1K83 A;  1CZ4 A;  3GTK A;  1VC3 B;  2YU9 A;  1QDN A;  1TWA A;  4C2M A;  5EPP A;  3GTP A;  1R27 A;  2B63 A;  1Y4Z A;  1E61 A;  2EEO B;  2A68 D;  2BE5 D;  2VPZ A;  4AYB A;  2A69 D;  2JA5 A;  3TIW A;  3PLX B;  1YLE A;  2E7Z A;  5B6C A;  1IW7 D;  3GTJ A;  4QIW A;  3O5A A;  2G6G A;  1E60 A;  1WCM A;  1Y1V A;  5T5M D;  4GA5 A;  4GA6 A;  2G5D A;  2JIM A;  3HU3 A;  3DMR A;  3QWZ A;  3TM7 B;  1Q16 A;  5T5I D;  3QQ8 A;  2C45 A;  1PQE A;  2VPX A;  2DMR A;  2JIO A;  1DMS A;  3GTL A;  3GTO A;  2O5J D;  5C1B A;  1UHE A;  2JA7 A;  2A6H D;  1EU1 A;  1PT0 A;  1G8K A;  1I3Q A;  2YUJ A;  2A6E D;  3HU2 A;  1H0H A;  2PI8 A;  5FTJ A;  5C18 A;  2V45 A;  1TMO A;  2CW0 D;  1SMY D;  1ZYR D;  1WLF A;  1FDI A;  2R92 A;  1FDO A;  1AW8 B;  3H0G A;  4KOD A;  1PQF A;  3IR5 A;  2GAE A;  3IR7 A;  2IV2 X;  1PPY A;  2NAP A;  3QQ7 A;  1UHD A;  2JA6 A;  1TWF A;  3GTG A;  1YNJ D;  3QC8 A;  4DMR A;  4CRY G;  5FTL A;  2E2H A;  2AE0 X;  1TWC A;  3IR6 A;  2PMZ A;  1ZC1 A;  2Y0S A;  5DYI A;  5FTN A;  4D7Z B;  3GTQ A;  3HKZ A;  1OGY A;  4AOK B;  2E2I A;  4CRZ A;  4AZD A;  1YNN D;  3FKI A;  2VPW A;  2R7Z A;  1PQH A;  1E5V A;  2PJH B;  4KO8 A;  1G8J A;  5DYG A;  1PYU B;  2VUM A;  2NVX A;  3HU1 A;  3CZB A;  1R9T A;  1CR5 A;  3GTM A;  1PT1 A;  1I50 A;  1Y5I A;  1E32 A;  2JIQ A;  1E18 A;  1R7R A;  1QCS A;  1S3S A;  4KDL A;  5FTM A;  4NOH A;  5FTK A;  2V3V A;  1KQF A;  4KDI A;  1TWH A;  2R93 A;  2NVY A;  2WB1 A;  1SFO A;  5GLF A;  1TWG A;  1KQG A;  2NYA A;  1DMR A;  2PJJ A;  1AA6 A;  2WAQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...