1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Aspartate 1-decarboxylase
publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
2R93A 1G8JA 1UHEA 1QDNA 2VPWA 5FTKA 4AAYA 1SFOA 2NVXA 3FKIA 3HU2A 2YU9A 1YLEA 4KDIA 4KODA 4RV0A 3GTMA 1KQFA 3GTQA 2JA7A 3GTOA 4CRYG 1DMRA 2E2IA 2JA6A 1E32A 5C1BA 1WCMA 1CZ4A 1TMOA 3IR7A 4GA6A 3HU3A 1KQGA 2E7ZA 2IV2X 3H0GA 5B6CA 2JIQA 1Y5IA 3IR6A 2PMZA 4KDLA 4AOKB 4CRZA 5FTNA 3GTJA 2E2HA 3OUGA 3GTLA 1TWFA 3CF2A 2VPXA 5GLFA 3O5AA 3QWZA 4AYBA 2WAQA 1TWGA 3QQ8A 1E5VA 1I50A 1CR5A 2PJHB 1PQFA 1PT1A 2NAPA 1PQHA 1H5NA 5FTJA 1TWAA 2R92A 1E60A 3GTGA 1E61A 4AONB 2B63A 4QIWA 1PYQA 4GA5A 2Y0SA 1EU1A 5FTLA 4D7ZB 2VPYA 1K83A 4C2MA 1FDOA 1AW8B 2NVYA 5C18A 1Y1WA 1S3SA 4KLNA 2R7ZA 1H0HA 2JIRA 2EEOB 3QQ7A 1WLFA 5DYGA 1R9TA 2VPZA 1UHDA 2DMRA 5DYIA 2JA5A 2V45A 3TM7B 3CQZA 2KI8A 3QC8A 1VC3B 5EPPA 1TWHA 1OGYA 1SIWA 2V3VA 1PPYA 2JIMA 2WB1A 1IW7D 2C45A 4DMRA 3TIWA 1QCSA 3DMRA 1Y1VA 2NYAA 1DMSA 3HU1A 3GTPA 1R27A 3GTKA 2JIOA 5FTMA 1FDIA 5T5MD 1PYUB 1TWCA 2VUMA 3IR5A 3ML1A 3HKZA 1PT0A 1AA6A 1E18A 1CZ5A 5T5ID 1Q16A 2JIPA 1I3QA 4KO8A 1Y4ZA 1G8KA 4AZDA 1PQEA 1R7RA 4CS0A 3PLXB
chains in the Genus database with same CATH superfamily
2R93A 1G8JA 1UHEA 1QDNA 2VPWA 5FTKA 4AAYA 1SFOA 2NVXA 3FKIA 3HU2A 2YU9A 1YLEA 3X2IA 1L8FA 4KDIA 4KODA 2A69D 1ZC1A 4RV0A 3GTMA 3SULA 1KQFA 4ZM7A 4FG2A 4AVRA 3GTQA 3GTOA 2JA7A 3X2MA 4CRYG 1DMRA 3X2HA 2E2IA 2JA6A 1E32A 1BW3A 5C1BA 2AE0X 1WCMA 1CZ4A 1TMOA 2PI8A 4FG4A 1BW4A 3IR7A 4GA6A 4FERA 3HU3A 1KQGA 2E7ZA 2IV2X 3H0GA 3M3GA 2HCZX 1YNJD 5B6CA 2JIQA 1Y5IA 3IR6A 2PMZA 2BE5D 4KDLA 4AOKB 5FTNA 4CRZA 2G5DA 3OUGA 3GTJA 1TWFA 3GTLA 2E2HA 3CF2A 2VPXA 5GLFA 1ZYRD 3O5AA 2GAEA 4JCWA 3QWZA 4AYBA 2O5JD 2WAQA 4JJOA 1TWGA 4ENGA 3QQ8A 1E5VA 1I50A 3SUJA 3SUKA 1CR5A 2PJHB 1PQFA 1PT1A 2NAPA 1PQHA 1H5NA 5FTJA 1OA9A 1TWAA 1YNND 2R92A 1E60A 3GTGA 1E61A 4AONB 2B63A 2ENGA 4QIWA 1PYQA 3X2OA 4GA5A 3X2NA 2A68D 2Y0SA 1EU1A 5FTLA 4D7ZB 2VPYA 1K83A 3CZBA 4C2MA 3ENGA 1FDOA 1AW8B 2NVYA 5C18A 4NOHA 1S3SA 1Y1WA 1HD5A 4KLNA 2R7ZA 1H0HA 2JIRA 2EEOB 3QQ7A 1WLFA 5GLXA 5DYGA 1R9TA 2VPZA 2YUJA 1UHDA 2DMRA 5DYIA 2JA5A 5H4UA 1N10A 3D30A 2V45A 3TM7B 4L48A 1WC2A 3CQZA 2KI8A 2KQAA 1VC3B 3QC8A 5EPPA 1TWHA 1OGYA 1SIWA 2V3VA 2CW0D 3X2PA 1PPYA 2JIMA 2WB1A 1IW7D 2A6HD 2C45A 3X2JA 4DMRA 4JS7A 3TIWA 1QCSA 2PICA 3SUMA 4FFTA 3DMRA 1Y1VA 2NYAA 2G6GA 1DMSA 3X2LA 3HU1A 3GTPA 1R27A 2A6ED 3GTKA 2JIOA 3X2GA 5FTMA 1FDIA 5T5MD 1PYUB 1TWCA 2VUMA 3IR5A 3ML1A 3HKZA 1PT0A 1OA7A 5GLYA 1AA6A 4JP6A 1E18A 1CZ5A 2PJJA 5T5ID 1Q16A 2JIPA 1I3QA 5GM9A 2BH0A 4KO8A 1Y4ZA 1G8KA 1SMYD 4JP7A 4AZDA 1PQEA 1R7RA 2PNWA 4CS0A 3PLXB 3X2KA
chains in the Genus database with same CATH topology
2R93A 1G8JA 1UHEA 1QDNA 2VPWA 5FTKA 4AAYA 1SFOA 2NVXA 3FKIA 3HU2A 2YU9A 1YLEA 4KDIA 4KODA 2A69D 1ZC1A 4RV0A 3GTMA 1KQFA 3GTQA 2JA7A 3GTOA 4CRYG 1DMRA 2E2IA 2JA6A 1E32A 5C1BA 2AE0X 1WCMA 1CZ4A 1TMOA 2PI8A 3IR7A 4GA6A 3HU3A 1KQGA 2E7ZA 2IV2X 3H0GA 1YNJD 5B6CA 2JIQA 1Y5IA 3IR6A 2PMZA 2BE5D 4KDLA 4AOKB 5FTNA 4CRZA 2G5DA 3OUGA 3GTJA 1TWFA 3GTLA 2E2HA 3CF2A 2VPXA 5GLFA 1ZYRD 3O5AA 2GAEA 3QWZA 4AYBA 2O5JD 2WAQA 1TWGA 3QQ8A 1E5VA 1I50A 1CR5A 2PJHB 1PQFA 1PT1A 2NAPA 1PQHA 1H5NA 5FTJA 1TWAA 1YNND 2R92A 1E60A 3GTGA 1E61A 4AONB 2B63A 4QIWA 1PYQA 4GA5A 2A68D 2Y0SA 1EU1A 5FTLA 4D7ZB 2VPYA 1K83A 3CZBA 4C2MA 1FDOA 1AW8B 2NVYA 5C18A 4NOHA 1S3SA 1Y1WA 4KLNA 2R7ZA 1H0HA 2JIRA 2EEOB 3QQ7A 1WLFA 5DYGA 1R9TA 2VPZA 2YUJA 1UHDA 2DMRA 5DYIA 2JA5A 2V45A 3TM7B 3CQZA 2KI8A 3QC8A 1VC3B 5EPPA 1TWHA 1OGYA 1SIWA 2V3VA 2CW0D 1PPYA 2JIMA 2WB1A 1IW7D 2A6HD 2C45A 4DMRA 3TIWA 1QCSA 2PICA 3DMRA 1Y1VA 2NYAA 2G6GA 1DMSA 3HU1A 3GTPA 1R27A 2A6ED 3GTKA 2JIOA 5FTMA 1FDIA 5T5MD 1PYUB 1TWCA 2VUMA 3IR5A 3ML1A 3HKZA 1PT0A 1AA6A 1E18A 1CZ5A 2PJJA 5T5ID 1Q16A 2JIPA 1I3QA 4KO8A 1Y4ZA 1G8KA 1SMYD 4AZDA 1PQEA 1R7RA 2PNWA 4CS0A 3PLXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R93 A;  1G8J A;  1UHE A;  1QDN A;  2VPW A;  5FTK A;  4AAY A;  1SFO A;  2NVX A;  3FKI A;  3HU2 A;  2YU9 A;  1YLE A;  4KDI A;  4KOD A;  4RV0 A;  3GTM A;  1KQF A;  3GTQ A;  2JA7 A;  3GTO A;  4CRY G;  1DMR A;  2E2I A;  2JA6 A;  1E32 A;  5C1B A;  1WCM A;  1CZ4 A;  1TMO A;  3IR7 A;  4GA6 A;  3HU3 A;  1KQG A;  2E7Z A;  2IV2 X;  3H0G A;  5B6C A;  2JIQ A;  1Y5I A;  3IR6 A;  2PMZ A;  4KDL A;  4AOK B;  4CRZ A;  5FTN A;  3GTJ A;  2E2H A;  3OUG A;  3GTL A;  1TWF A;  3CF2 A;  2VPX A;  5GLF A;  3O5A A;  3QWZ A;  4AYB A;  2WAQ A;  1TWG A;  3QQ8 A;  1E5V A;  1I50 A;  1CR5 A;  2PJH B;  1PQF A;  1PT1 A;  2NAP A;  1PQH A;  1H5N A;  5FTJ A;  1TWA A;  2R92 A;  1E60 A;  3GTG A;  1E61 A;  4AON B;  2B63 A;  4QIW A;  1PYQ A;  4GA5 A;  2Y0S A;  1EU1 A;  5FTL A;  4D7Z B;  2VPY A;  1K83 A;  4C2M A;  1FDO A;  1AW8 B;  2NVY A;  5C18 A;  1Y1W A;  1S3S A;  4KLN A;  2R7Z A;  1H0H A;  2JIR A;  2EEO B;  3QQ7 A;  1WLF A;  5DYG A;  1R9T A;  2VPZ A;  1UHD A;  2DMR A;  5DYI A;  2JA5 A;  2V45 A;  3TM7 B;  3CQZ A;  2KI8 A;  3QC8 A;  1VC3 B;  5EPP A;  1TWH A;  1OGY A;  1SIW A;  2V3V A;  1PPY A;  2JIM A;  2WB1 A;  1IW7 D;  2C45 A;  4DMR A;  3TIW A;  1QCS A;  3DMR A;  1Y1V A;  2NYA A;  1DMS A;  3HU1 A;  3GTP A;  1R27 A;  3GTK A;  2JIO A;  5FTM A;  1FDI A;  5T5M D;  1PYU B;  1TWC A;  2VUM A;  3IR5 A;  3ML1 A;  3HKZ A;  1PT0 A;  1AA6 A;  1E18 A;  1CZ5 A;  5T5I D;  1Q16 A;  2JIP A;  1I3Q A;  4KO8 A;  1Y4Z A;  1G8K A;  4AZD A;  1PQE A;  1R7R A;  4CS0 A;  3PLX B; 
#chains in the Genus database with same CATH topology
 2R93 A;  1G8J A;  1UHE A;  1QDN A;  2VPW A;  5FTK A;  4AAY A;  1SFO A;  2NVX A;  3FKI A;  3HU2 A;  2YU9 A;  1YLE A;  3X2I A;  1L8F A;  4KDI A;  4KOD A;  2A69 D;  1ZC1 A;  4RV0 A;  3GTM A;  3SUL A;  1KQF A;  4ZM7 A;  4FG2 A;  4AVR A;  3GTQ A;  3GTO A;  2JA7 A;  3X2M A;  4CRY G;  1DMR A;  3X2H A;  2E2I A;  2JA6 A;  1E32 A;  1BW3 A;  5C1B A;  2AE0 X;  1WCM A;  1CZ4 A;  1TMO A;  2PI8 A;  4FG4 A;  1BW4 A;  3IR7 A;  4GA6 A;  4FER A;  3HU3 A;  1KQG A;  2E7Z A;  2IV2 X;  3H0G A;  3M3G A;  2HCZ X;  1YNJ D;  5B6C A;  2JIQ A;  1Y5I A;  3IR6 A;  2PMZ A;  2BE5 D;  4KDL A;  4AOK B;  5FTN A;  4CRZ A;  2G5D A;  3OUG A;  3GTJ A;  1TWF A;  3GTL A;  2E2H A;  3CF2 A;  2VPX A;  5GLF A;  1ZYR D;  3O5A A;  2GAE A;  4JCW A;  3QWZ A;  4AYB A;  2O5J D;  2WAQ A;  4JJO A;  1TWG A;  4ENG A;  3QQ8 A;  1E5V A;  1I50 A;  3SUJ A;  3SUK A;  1CR5 A;  2PJH B;  1PQF A;  1PT1 A;  2NAP A;  1PQH A;  1H5N A;  5FTJ A;  1OA9 A;  1TWA A;  1YNN D;  2R92 A;  1E60 A;  3GTG A;  1E61 A;  4AON B;  2B63 A;  2ENG A;  4QIW A;  1PYQ A;  3X2O A;  4GA5 A;  3X2N A;  2A68 D;  2Y0S A;  1EU1 A;  5FTL A;  4D7Z B;  2VPY A;  1K83 A;  3CZB A;  4C2M A;  3ENG A;  1FDO A;  1AW8 B;  2NVY A;  5C18 A;  4NOH A;  1S3S A;  1Y1W A;  1HD5 A;  4KLN A;  2R7Z A;  1H0H A;  2JIR A;  2EEO B;  3QQ7 A;  1WLF A;  5GLX A;  5DYG A;  1R9T A;  2VPZ A;  2YUJ A;  1UHD A;  2DMR A;  5DYI A;  2JA5 A;  5H4U A;  1N10 A;  3D30 A;  2V45 A;  3TM7 B;  4L48 A;  1WC2 A;  3CQZ A;  2KI8 A;  2KQA A;  1VC3 B;  3QC8 A;  5EPP A;  1TWH A;  1OGY A;  1SIW A;  2V3V A;  2CW0 D;  3X2P A;  1PPY A;  2JIM A;  2WB1 A;  1IW7 D;  2A6H D;  2C45 A;  3X2J A;  4DMR A;  4JS7 A;  3TIW A;  1QCS A;  2PIC A;  3SUM A;  4FFT A;  3DMR A;  1Y1V A;  2NYA A;  2G6G A;  1DMS A;  3X2L A;  3HU1 A;  3GTP A;  1R27 A;  2A6E D;  3GTK A;  2JIO A;  3X2G A;  5FTM A;  1FDI A;  5T5M D;  1PYU B;  1TWC A;  2VUM A;  3IR5 A;  3ML1 A;  3HKZ A;  1PT0 A;  1OA7 A;  5GLY A;  1AA6 A;  4JP6 A;  1E18 A;  1CZ5 A;  2PJJ A;  5T5I D;  1Q16 A;  2JIP A;  1I3Q A;  5GM9 A;  2BH0 A;  4KO8 A;  1Y4Z A;  1G8K A;  1SMY D;  4JP7 A;  4AZD A;  1PQE A;  1R7R A;  2PNW A;  4CS0 A;  3PLX B;  3X2K A; 
#chains in the Genus database with same CATH homology
 2R93 A;  1G8J A;  1UHE A;  1QDN A;  2VPW A;  5FTK A;  4AAY A;  1SFO A;  2NVX A;  3FKI A;  3HU2 A;  2YU9 A;  1YLE A;  4KDI A;  4KOD A;  2A69 D;  1ZC1 A;  4RV0 A;  3GTM A;  1KQF A;  3GTQ A;  2JA7 A;  3GTO A;  4CRY G;  1DMR A;  2E2I A;  2JA6 A;  1E32 A;  5C1B A;  2AE0 X;  1WCM A;  1CZ4 A;  1TMO A;  2PI8 A;  3IR7 A;  4GA6 A;  3HU3 A;  1KQG A;  2E7Z A;  2IV2 X;  3H0G A;  1YNJ D;  5B6C A;  2JIQ A;  1Y5I A;  3IR6 A;  2PMZ A;  2BE5 D;  4KDL A;  4AOK B;  5FTN A;  4CRZ A;  2G5D A;  3OUG A;  3GTJ A;  1TWF A;  3GTL A;  2E2H A;  3CF2 A;  2VPX A;  5GLF A;  1ZYR D;  3O5A A;  2GAE A;  3QWZ A;  4AYB A;  2O5J D;  2WAQ A;  1TWG A;  3QQ8 A;  1E5V A;  1I50 A;  1CR5 A;  2PJH B;  1PQF A;  1PT1 A;  2NAP A;  1PQH A;  1H5N A;  5FTJ A;  1TWA A;  1YNN D;  2R92 A;  1E60 A;  3GTG A;  1E61 A;  4AON B;  2B63 A;  4QIW A;  1PYQ A;  4GA5 A;  2A68 D;  2Y0S A;  1EU1 A;  5FTL A;  4D7Z B;  2VPY A;  1K83 A;  3CZB A;  4C2M A;  1FDO A;  1AW8 B;  2NVY A;  5C18 A;  4NOH A;  1S3S A;  1Y1W A;  4KLN A;  2R7Z A;  1H0H A;  2JIR A;  2EEO B;  3QQ7 A;  1WLF A;  5DYG A;  1R9T A;  2VPZ A;  2YUJ A;  1UHD A;  2DMR A;  5DYI A;  2JA5 A;  2V45 A;  3TM7 B;  3CQZ A;  2KI8 A;  3QC8 A;  1VC3 B;  5EPP A;  1TWH A;  1OGY A;  1SIW A;  2V3V A;  2CW0 D;  1PPY A;  2JIM A;  2WB1 A;  1IW7 D;  2A6H D;  2C45 A;  4DMR A;  3TIW A;  1QCS A;  2PIC A;  3DMR A;  1Y1V A;  2NYA A;  2G6G A;  1DMS A;  3HU1 A;  3GTP A;  1R27 A;  2A6E D;  3GTK A;  2JIO A;  5FTM A;  1FDI A;  5T5M D;  1PYU B;  1TWC A;  2VUM A;  3IR5 A;  3ML1 A;  3HKZ A;  1PT0 A;  1AA6 A;  1E18 A;  1CZ5 A;  2PJJ A;  5T5I D;  1Q16 A;  2JIP A;  1I3Q A;  4KO8 A;  1Y4Z A;  1G8K A;  1SMY D;  4AZD A;  1PQE A;  1R7R A;  2PNW A;  4CS0 A;  3PLX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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