1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
b'RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Aspartate 1-decarboxylase
publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
1TWCA 4CS0A 3OUGA 1UHDA 2V45A 1AW8B 1SIWA 2NVYA 2PMZA 1I3QA 2E7ZA 5FTNA 3H0GA 1WCMA 1Y5IA 3FKIA 3GTMA 1TWAA 5GLFA 5B6CA 5T5MD 1PQFA 2IV2X 3QC8A 1PYQA 3TM7B 3QWZA 2JIQA 1E61A 2V3VA 5FTKA 1I50A 1K83A 3HU1A 4KLNA 1CZ4A 2Y0SA 3HKZA 1Q16A 2JA5A 1IW7D 2DMRA 5FTLA 1YLEA 1G8JA 2JIMA 4KDIA 2JA7A 2E2IA 4AAYA 2JIRA 1FDOA 5C1BA 2VUMA 5DYGA 2YU9A 4CRYG 3IR7A 3GTKA 3QQ8A 1CR5A 1PQEA 1OGYA 4AYBA 1TMOA 2WAQA 4AONB 1DMRA 1QCSA 3ML1A 3TIWA 2VPZA 3IR6A 3GTPA 1E60A 2JIOA 3QQ7A 1E32A 4AZDA 2VPWA 1UHEA 1VC3B 2R92A 1G8KA 2EEOB 2NVXA 1KQGA 5C18A 4D7ZB 2C45A 4CRZA 3GTLA 4KODA 1QDNA 2JIPA 3DMRA 1PT1A 2JA6A 1DMSA 1E5VA 1PYUB 1CZ5A 4C2MA 3IR5A 3CQZA 3CF2A 2NYAA 5FTJA 4GA6A 3GTGA 1Y4ZA 1R27A 1WLFA 4KO8A 4AOKB 2VPYA 4KDLA 2B63A 5T5ID 2R93A 4RV0A 3GTQA 3HU3A 1S3SA 4QIWA 1TWGA 5EPPA 2R7ZA 2NAPA 1SFOA 1E18A 1PPYA 3O5AA 1H0HA 3PLXB 5FTMA 1Y1VA 2E2HA 1PQHA 2WB1A 4DMRA 1PT0A 2PJHB 1TWFA 1FDIA 5DYIA 1R9TA 1H5NA 1EU1A 3GTJA 1Y1WA 4GA5A 3HU2A 3GTOA 1R7RA 2KI8A 1TWHA 1KQFA 2VPXA 1AA6A
chains in the Genus database with same CATH superfamily
1TWCA 4CS0A 3OUGA 1UHDA 2V45A 1AW8B 1SIWA 5GM9A 1WC2A 2NVYA 2A6ED 4AVRA 1OA9A 2PMZA 2A69D 2E7ZA 1I3QA 5FTNA 3H0GA 2CW0D 1WCMA 1Y5IA 3FKIA 3GTMA 1TWAA 5GLFA 5B6CA 2G5DA 4JJOA 5T5MD 2PI8A 1PQFA 2HCZX 2IV2X 3QC8A 1PYQA 3SUMA 2A68D 3QWZA 2JIQA 3TM7B 1E61A 5GLYA 2V3VA 5FTKA 1I50A 3X2LA 1K83A 3D30A 3HU1A 3X2NA 4KLNA 5GLXA 1CZ4A 2PICA 2Y0SA 3HKZA 2ENGA 1Q16A 2JA5A 1IW7D 2PJJA 2DMRA 1BW4A 5FTLA 1YLEA 1G8JA 2KQAA 2JIMA 4JCWA 4KDIA 4L48A 2JA7A 2E2IA 4AAYA 2JIRA 1FDOA 2A6HD 5C1BA 3ENGA 2VUMA 1ZYRD 5DYGA 2YU9A 1YNND 4CRYG 2BE5D 3IR7A 3GTKA 2AE0X 3QQ8A 1CR5A 4FFTA 1PQEA 1OGYA 4AYBA 1TMOA 2WAQA 3X2JA 4FERA 4AONB 1DMRA 1OA7A 1QCSA 3M3GA 2VPZA 2G6GA 2YUJA 3ML1A 1N10A 3IR6A 3GTPA 1E60A 2JIOA 3QQ7A 1KQFA 3SUKA 2BH0A 1E32A 4AZDA 1UHEA 1VC3B 2VPWA 2R92A 1G8KA 2EEOB 1BW3A 2NVXA 1KQGA 2GAEA 3CZBA 2O5JD 3X2GA 5C18A 4D7ZB 2C45A 3SULA 4CRZA 3GTLA 3X2MA 4KODA 1ZC1A 1QDNA 3X2OA 2JIPA 3DMRA 1PT1A 2JA6A 1DMSA 1E5VA 1PYUB 5H4UA 4ZM7A 1CZ5A 4C2MA 3IR5A 3CQZA 3CF2A 2NYAA 5FTJA 4GA6A 4ENGA 3GTGA 4NOHA 4JS7A 1Y4ZA 1R27A 1WLFA 4KO8A 1L8FA 4JP7A 3X2IA 4AOKB 2PNWA 2VPYA 4KDLA 2B63A 5T5ID 2R93A 4RV0A 3X2KA 1HD5A 3GTQA 3HU3A 1S3SA 4QIWA 1TWGA 5EPPA 2R7ZA 2NAPA 1SFOA 3X2PA 1E18A 1PPYA 3O5AA 1H0HA 3PLXB 4FG2A 1Y1VA 5FTMA 3SUJA 2E2HA 1PQHA 2WB1A 4DMRA 1PT0A 2PJHB 1TWFA 1FDIA 5DYIA 3X2HA 1R9TA 1H5NA 1EU1A 4FG4A 3GTJA 1Y1WA 1YNJD 3HU2A 4GA5A 3TIWA 3GTOA 1R7RA 2KI8A 1SMYD 1TWHA 4JP6A 2VPXA 1AA6A
chains in the Genus database with same CATH topology
1TWCA 4CS0A 3OUGA 1UHDA 2V45A 1AW8B 1SIWA 2NVYA 2A6ED 2PMZA 2A69D 2E7ZA 1I3QA 5FTNA 3H0GA 2CW0D 1WCMA 1Y5IA 3FKIA 3GTMA 1TWAA 5GLFA 5B6CA 2G5DA 5T5MD 2PI8A 1PQFA 2IV2X 3QC8A 1PYQA 3TM7B 2A68D 3QWZA 2JIQA 1E61A 2V3VA 5FTKA 1I50A 1K83A 3HU1A 4KLNA 1CZ4A 2PICA 2Y0SA 3HKZA 1Q16A 2JA5A 1IW7D 2PJJA 2DMRA 5FTLA 1YLEA 1G8JA 2JIMA 4KDIA 2JA7A 2E2IA 4AAYA 2JIRA 1FDOA 2A6HD 5C1BA 2VUMA 1ZYRD 5DYGA 2YU9A 1YNND 4CRYG 2BE5D 3IR7A 3GTKA 2AE0X 3QQ8A 1CR5A 1PQEA 1OGYA 4AYBA 1TMOA 2WAQA 4AONB 1DMRA 1QCSA 3ML1A 3TIWA 2VPZA 2G6GA 2YUJA 3IR6A 3GTPA 1E60A 2JIOA 3QQ7A 1E32A 4AZDA 1UHEA 1VC3B 2VPWA 2R92A 1G8KA 2EEOB 2NVXA 1KQGA 2GAEA 3CZBA 2O5JD 5C18A 4D7ZB 2C45A 4CRZA 3GTLA 4KODA 1ZC1A 1QDNA 2JIPA 3DMRA 1PT1A 2JA6A 1DMSA 1E5VA 1PYUB 1CZ5A 4C2MA 3IR5A 3CQZA 3CF2A 2NYAA 5FTJA 4GA6A 3GTGA 4NOHA 1Y4ZA 1R27A 1WLFA 4KO8A 4AOKB 2PNWA 2VPYA 4KDLA 2B63A 5T5ID 2R93A 4RV0A 3GTQA 3HU3A 1S3SA 4QIWA 1TWGA 5EPPA 2R7ZA 2NAPA 1SFOA 1E18A 1PPYA 3O5AA 1H0HA 3PLXB 5FTMA 1Y1VA 2E2HA 1PQHA 2WB1A 4DMRA 1PT0A 2PJHB 1TWFA 1FDIA 5DYIA 1R9TA 1H5NA 1EU1A 3GTJA 1Y1WA 1YNJD 3HU2A 4GA5A 3GTOA 1R7RA 2KI8A 1SMYD 1TWHA 1KQFA 2VPXA 1AA6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWC A;  4CS0 A;  3OUG A;  1UHD A;  2V45 A;  1AW8 B;  1SIW A;  2NVY A;  2PMZ A;  1I3Q A;  2E7Z A;  5FTN A;  3H0G A;  1WCM A;  1Y5I A;  3FKI A;  3GTM A;  1TWA A;  5GLF A;  5B6C A;  5T5M D;  1PQF A;  2IV2 X;  3QC8 A;  1PYQ A;  3TM7 B;  3QWZ A;  2JIQ A;  1E61 A;  2V3V A;  5FTK A;  1I50 A;  1K83 A;  3HU1 A;  4KLN A;  1CZ4 A;  2Y0S A;  3HKZ A;  1Q16 A;  2JA5 A;  1IW7 D;  2DMR A;  5FTL A;  1YLE A;  1G8J A;  2JIM A;  4KDI A;  2JA7 A;  2E2I A;  4AAY A;  2JIR A;  1FDO A;  5C1B A;  2VUM A;  5DYG A;  2YU9 A;  4CRY G;  3IR7 A;  3GTK A;  3QQ8 A;  1CR5 A;  1PQE A;  1OGY A;  4AYB A;  1TMO A;  2WAQ A;  4AON B;  1DMR A;  1QCS A;  3ML1 A;  3TIW A;  2VPZ A;  3IR6 A;  3GTP A;  1E60 A;  2JIO A;  3QQ7 A;  1E32 A;  4AZD A;  2VPW A;  1UHE A;  1VC3 B;  2R92 A;  1G8K A;  2EEO B;  2NVX A;  1KQG A;  5C18 A;  4D7Z B;  2C45 A;  4CRZ A;  3GTL A;  4KOD A;  1QDN A;  2JIP A;  3DMR A;  1PT1 A;  2JA6 A;  1DMS A;  1E5V A;  1PYU B;  1CZ5 A;  4C2M A;  3IR5 A;  3CQZ A;  3CF2 A;  2NYA A;  5FTJ A;  4GA6 A;  3GTG A;  1Y4Z A;  1R27 A;  1WLF A;  4KO8 A;  4AOK B;  2VPY A;  4KDL A;  2B63 A;  5T5I D;  2R93 A;  4RV0 A;  3GTQ A;  3HU3 A;  1S3S A;  4QIW A;  1TWG A;  5EPP A;  2R7Z A;  2NAP A;  1SFO A;  1E18 A;  1PPY A;  3O5A A;  1H0H A;  3PLX B;  5FTM A;  1Y1V A;  2E2H A;  1PQH A;  2WB1 A;  4DMR A;  1PT0 A;  2PJH B;  1TWF A;  1FDI A;  5DYI A;  1R9T A;  1H5N A;  1EU1 A;  3GTJ A;  1Y1W A;  4GA5 A;  3HU2 A;  3GTO A;  1R7R A;  2KI8 A;  1TWH A;  1KQF A;  2VPX A;  1AA6 A; 
#chains in the Genus database with same CATH topology
 1TWC A;  4CS0 A;  3OUG A;  1UHD A;  2V45 A;  1AW8 B;  1SIW A;  5GM9 A;  1WC2 A;  2NVY A;  2A6E D;  4AVR A;  1OA9 A;  2PMZ A;  2A69 D;  2E7Z A;  1I3Q A;  5FTN A;  3H0G A;  2CW0 D;  1WCM A;  1Y5I A;  3FKI A;  3GTM A;  1TWA A;  5GLF A;  5B6C A;  2G5D A;  4JJO A;  5T5M D;  2PI8 A;  1PQF A;  2HCZ X;  2IV2 X;  3QC8 A;  1PYQ A;  3SUM A;  2A68 D;  3QWZ A;  2JIQ A;  3TM7 B;  1E61 A;  5GLY A;  2V3V A;  5FTK A;  1I50 A;  3X2L A;  1K83 A;  3D30 A;  3HU1 A;  3X2N A;  4KLN A;  5GLX A;  1CZ4 A;  2PIC A;  2Y0S A;  3HKZ A;  2ENG A;  1Q16 A;  2JA5 A;  1IW7 D;  2PJJ A;  2DMR A;  1BW4 A;  5FTL A;  1YLE A;  1G8J A;  2KQA A;  2JIM A;  4JCW A;  4KDI A;  4L48 A;  2JA7 A;  2E2I A;  4AAY A;  2JIR A;  1FDO A;  2A6H D;  5C1B A;  3ENG A;  2VUM A;  1ZYR D;  5DYG A;  2YU9 A;  1YNN D;  4CRY G;  2BE5 D;  3IR7 A;  3GTK A;  2AE0 X;  3QQ8 A;  1CR5 A;  4FFT A;  1PQE A;  1OGY A;  4AYB A;  1TMO A;  2WAQ A;  3X2J A;  4FER A;  4AON B;  1DMR A;  1OA7 A;  1QCS A;  3M3G A;  2VPZ A;  2G6G A;  2YUJ A;  3ML1 A;  1N10 A;  3IR6 A;  3GTP A;  1E60 A;  2JIO A;  3QQ7 A;  1KQF A;  3SUK A;  2BH0 A;  1E32 A;  4AZD A;  1UHE A;  1VC3 B;  2VPW A;  2R92 A;  1G8K A;  2EEO B;  1BW3 A;  2NVX A;  1KQG A;  2GAE A;  3CZB A;  2O5J D;  3X2G A;  5C18 A;  4D7Z B;  2C45 A;  3SUL A;  4CRZ A;  3GTL A;  3X2M A;  4KOD A;  1ZC1 A;  1QDN A;  3X2O A;  2JIP A;  3DMR A;  1PT1 A;  2JA6 A;  1DMS A;  1E5V A;  1PYU B;  5H4U A;  4ZM7 A;  1CZ5 A;  4C2M A;  3IR5 A;  3CQZ A;  3CF2 A;  2NYA A;  5FTJ A;  4GA6 A;  4ENG A;  3GTG A;  4NOH A;  4JS7 A;  1Y4Z A;  1R27 A;  1WLF A;  4KO8 A;  1L8F A;  4JP7 A;  3X2I A;  4AOK B;  2PNW A;  2VPY A;  4KDL A;  2B63 A;  5T5I D;  2R93 A;  4RV0 A;  3X2K A;  1HD5 A;  3GTQ A;  3HU3 A;  1S3S A;  4QIW A;  1TWG A;  5EPP A;  2R7Z A;  2NAP A;  1SFO A;  3X2P A;  1E18 A;  1PPY A;  3O5A A;  1H0H A;  3PLX B;  4FG2 A;  1Y1V A;  5FTM A;  3SUJ A;  2E2H A;  1PQH A;  2WB1 A;  4DMR A;  1PT0 A;  2PJH B;  1TWF A;  1FDI A;  5DYI A;  3X2H A;  1R9T A;  1H5N A;  1EU1 A;  4FG4 A;  3GTJ A;  1Y1W A;  1YNJ D;  3HU2 A;  4GA5 A;  3TIW A;  3GTO A;  1R7R A;  2KI8 A;  1SMY D;  1TWH A;  4JP6 A;  2VPX A;  1AA6 A; 
#chains in the Genus database with same CATH homology
 1TWC A;  4CS0 A;  3OUG A;  1UHD A;  2V45 A;  1AW8 B;  1SIW A;  2NVY A;  2A6E D;  2PMZ A;  2A69 D;  2E7Z A;  1I3Q A;  5FTN A;  3H0G A;  2CW0 D;  1WCM A;  1Y5I A;  3FKI A;  3GTM A;  1TWA A;  5GLF A;  5B6C A;  2G5D A;  5T5M D;  2PI8 A;  1PQF A;  2IV2 X;  3QC8 A;  1PYQ A;  3TM7 B;  2A68 D;  3QWZ A;  2JIQ A;  1E61 A;  2V3V A;  5FTK A;  1I50 A;  1K83 A;  3HU1 A;  4KLN A;  1CZ4 A;  2PIC A;  2Y0S A;  3HKZ A;  1Q16 A;  2JA5 A;  1IW7 D;  2PJJ A;  2DMR A;  5FTL A;  1YLE A;  1G8J A;  2JIM A;  4KDI A;  2JA7 A;  2E2I A;  4AAY A;  2JIR A;  1FDO A;  2A6H D;  5C1B A;  2VUM A;  1ZYR D;  5DYG A;  2YU9 A;  1YNN D;  4CRY G;  2BE5 D;  3IR7 A;  3GTK A;  2AE0 X;  3QQ8 A;  1CR5 A;  1PQE A;  1OGY A;  4AYB A;  1TMO A;  2WAQ A;  4AON B;  1DMR A;  1QCS A;  3ML1 A;  3TIW A;  2VPZ A;  2G6G A;  2YUJ A;  3IR6 A;  3GTP A;  1E60 A;  2JIO A;  3QQ7 A;  1E32 A;  4AZD A;  1UHE A;  1VC3 B;  2VPW A;  2R92 A;  1G8K A;  2EEO B;  2NVX A;  1KQG A;  2GAE A;  3CZB A;  2O5J D;  5C18 A;  4D7Z B;  2C45 A;  4CRZ A;  3GTL A;  4KOD A;  1ZC1 A;  1QDN A;  2JIP A;  3DMR A;  1PT1 A;  2JA6 A;  1DMS A;  1E5V A;  1PYU B;  1CZ5 A;  4C2M A;  3IR5 A;  3CQZ A;  3CF2 A;  2NYA A;  5FTJ A;  4GA6 A;  3GTG A;  4NOH A;  1Y4Z A;  1R27 A;  1WLF A;  4KO8 A;  4AOK B;  2PNW A;  2VPY A;  4KDL A;  2B63 A;  5T5I D;  2R93 A;  4RV0 A;  3GTQ A;  3HU3 A;  1S3S A;  4QIW A;  1TWG A;  5EPP A;  2R7Z A;  2NAP A;  1SFO A;  1E18 A;  1PPY A;  3O5A A;  1H0H A;  3PLX B;  5FTM A;  1Y1V A;  2E2H A;  1PQH A;  2WB1 A;  4DMR A;  1PT0 A;  2PJH B;  1TWF A;  1FDI A;  5DYI A;  1R9T A;  1H5N A;  1EU1 A;  3GTJ A;  1Y1W A;  1YNJ D;  3HU2 A;  4GA5 A;  3GTO A;  1R7R A;  2KI8 A;  1SMY D;  1TWH A;  1KQF A;  2VPX A;  1AA6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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