1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
molecule keywords Aspartate 1-decarboxylase
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
2C45A 1KQFA 3GTPA 2E7ZA 1H0HA 5T5ID 2E2HA 4AZDA 2JA6A 3O5AA 1OGYA 1TWFA 1PQHA 3DMRA 1KQGA 4CRYG 1EU1A 3GTJA 2VPXA 4KLNA 1TMOA 4CRZA 4DMRA 3HKZA 2NAPA 1DMRA 4GA6A 1K83A 1CZ4A 4GA5A 1Y1VA 2VPYA 3OUGA 1TWHA 5B6CA 1QCSA 1AW8B 4AAYA 3TM7B 3GTLA 2WAQA 1E18A 1I50A 2WB1A 3HU2A 5FTMA 1SIWA 1Y4ZA 2VPWA 3IR6A 1TWGA 2PJHB 1UHEA 4D7ZB 3IR5A 4QIWA 1PPYA 1PYUB 2YU9A 3GTQA 1PQEA 1AA6A 5DYIA 1PT1A 2JIRA 1R9TA 1PT0A 2JA5A 3FKIA 2PMZA 2KI8A 1FDIA 2VPZA 3QQ7A 5C18A 3PLXB 1PYQA 2JIOA 2JIMA 2B63A 5FTKA 3TIWA 4KODA 1Q16A 1UHDA 4KO8A 1FDOA 2NVXA 1QDNA 3GTKA 2V3VA 4C2MA 1IW7D 1WCMA 1I3QA 5C1BA 1G8KA 1VC3B 5FTJA 4KDLA 1S3SA 1CZ5A 2R7ZA 1E61A 2V45A 3HU3A 1TWCA 1CR5A 1TWAA 1PQFA 1E32A 3H0GA 3CF2A 5DYGA 3GTMA 4AOKB 3IR7A 2JIPA 3QC8A 2DMRA 1SFOA 3QQ8A 4AONB 2EEOB 2NYAA 4RV0A 1E60A 2NVYA 2R93A 1R27A 1YLEA 1WLFA 2VUMA 5FTLA 2E2IA 2Y0SA 4KDIA 1Y5IA 3QWZA 1H5NA 1R7RA 5FTNA 3HU1A 3GTOA 4AYBA 5T5MD 1E5VA 2JIQA 1Y1WA 3CQZA 1DMSA 3GTGA 1G8JA 2IV2X 2JA7A 2R92A 3ML1A 5EPPA 5GLFA 4CS0A
chains in the Genus database with same CATH superfamily
1SMYD 2C45A 1KQFA 3GTPA 2A6HD 2E7ZA 1H0HA 5T5ID 2E2HA 5H4UA 4AZDA 2JA6A 3SUMA 2HCZX 3O5AA 2G6GA 1OGYA 4JJOA 1TWFA 1PQHA 1L8FA 3DMRA 4CRYG 1KQGA 1EU1A 3GTJA 2VPXA 5GM9A 4KLNA 1TMOA 4FFTA 5GLXA 4CRZA 3HKZA 2NAPA 1DMRA 4GA6A 4DMRA 4FG2A 1K83A 1CZ4A 4GA5A 1Y1VA 2VPYA 3OUGA 1TWHA 3SUJA 5B6CA 1QCSA 1WC2A 1AW8B 3SUKA 4AAYA 4JS7A 3TM7B 3GTLA 3X2NA 3M3GA 2WAQA 1E18A 1I50A 4JP6A 2WB1A 1BW4A 3HU2A 5FTMA 1SIWA 5GLYA 3X2PA 2G5DA 2A69D 1Y4ZA 2VPWA 3IR6A 1TWGA 2PJHB 1UHEA 2BH0A 1ZC1A 4D7ZB 4JCWA 3IR5A 4QIWA 1HD5A 1PPYA 1PYUB 2YU9A 4NOHA 3GTQA 1PQEA 1AA6A 5DYIA 3X2KA 4ZM7A 1PT1A 2CW0D 2A68D 2JIRA 1R9TA 3X2IA 2GAEA 1PT0A 3SULA 3FKIA 2JA5A 3X2MA 2AE0X 2PMZA 2KI8A 3CZBA 1FDIA 2VPZA 3QQ7A 5C18A 3ENGA 3PLXB 3X2LA 2PJJA 1PYQA 2JIOA 2BE5D 2JIMA 2B63A 5FTKA 3TIWA 4KODA 1Q16A 1UHDA 4KO8A 2ENGA 1FDOA 2A6ED 2NVXA 1QDNA 4ENGA 2O5JD 3GTKA 2V3VA 4C2MA 1IW7D 1OA7A 1WCMA 1I3QA 5C1BA 1G8KA 1VC3B 5FTJA 4KDLA 1S3SA 1CZ5A 2R7ZA 3X2GA 1E61A 2V45A 3HU3A 1TWCA 1CR5A 1TWAA 1PQFA 1E32A 3D30A 3CF2A 3H0GA 5DYGA 3X2JA 2PNWA 2KQAA 3GTMA 4AOKB 3IR7A 2JIPA 3QC8A 2DMRA 1SFOA 4FERA 4L48A 3QQ8A 1ZYRD 4AONB 2EEOB 2NYAA 4RV0A 1YNJD 1E60A 3X2HA 1BW3A 1N10A 2NVYA 2R93A 1R27A 1YLEA 5GLFA 1WLFA 2VUMA 2PI8A 5FTLA 2E2IA 2Y0SA 4KDIA 1Y5IA 3QWZA 4FG4A 1H5NA 1R7RA 5FTNA 3HU1A 3GTOA 4AYBA 1YNND 5T5MD 1E5VA 2JIQA 1OA9A 1Y1WA 3X2OA 3CQZA 1DMSA 4JP7A 3GTGA 1G8JA 2IV2X 2JA7A 2R92A 3ML1A 2PICA 5EPPA 2YUJA 4CS0A 4AVRA
chains in the Genus database with same CATH topology
1SMYD 2C45A 1KQFA 3GTPA 2A6HD 2E7ZA 1H0HA 5T5ID 2E2HA 4AZDA 2JA6A 3O5AA 2G6GA 1OGYA 1TWFA 1PQHA 3DMRA 1KQGA 4CRYG 1EU1A 3GTJA 2VPXA 4KLNA 1TMOA 4CRZA 4DMRA 3HKZA 2NAPA 1DMRA 4GA6A 1K83A 1CZ4A 4GA5A 1Y1VA 2VPYA 3OUGA 1TWHA 5B6CA 1QCSA 1AW8B 4AAYA 3TM7B 3GTLA 2WAQA 1E18A 1I50A 2WB1A 3HU2A 5FTMA 1SIWA 2G5DA 2A69D 1Y4ZA 2VPWA 3IR6A 1TWGA 2PJHB 1UHEA 1ZC1A 4D7ZB 3IR5A 4QIWA 1PPYA 1PYUB 2YU9A 4NOHA 3GTQA 1PQEA 1AA6A 5DYIA 1PT1A 2CW0D 2A68D 2JIRA 1R9TA 2GAEA 1PT0A 2JA5A 3FKIA 2AE0X 2PMZA 2KI8A 3CZBA 1FDIA 2VPZA 3QQ7A 5C18A 3PLXB 2PJJA 1PYQA 2JIOA 2BE5D 2JIMA 2B63A 5FTKA 3TIWA 4KODA 1Q16A 1UHDA 4KO8A 1FDOA 2A6ED 2NVXA 1QDNA 2O5JD 3GTKA 2V3VA 4C2MA 1IW7D 1WCMA 1I3QA 5C1BA 1G8KA 1VC3B 5FTJA 4KDLA 1S3SA 1CZ5A 2R7ZA 1E61A 2V45A 3HU3A 1TWCA 1CR5A 1TWAA 1PQFA 1E32A 3H0GA 3CF2A 5DYGA 2PNWA 3GTMA 4AOKB 3IR7A 2JIPA 3QC8A 2DMRA 1SFOA 3QQ8A 1ZYRD 4AONB 2EEOB 2NYAA 4RV0A 1YNJD 1E60A 2NVYA 2R93A 1R27A 1YLEA 5GLFA 1WLFA 2VUMA 2PI8A 5FTLA 2E2IA 2Y0SA 4KDIA 1Y5IA 3QWZA 1H5NA 1R7RA 5FTNA 3HU1A 3GTOA 4AYBA 1YNND 5T5MD 1E5VA 2JIQA 1Y1WA 3CQZA 1DMSA 3GTGA 1G8JA 2IV2X 2JA7A 2R92A 3ML1A 2PICA 5EPPA 2YUJA 4CS0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C45 A;  1KQF A;  3GTP A;  2E7Z A;  1H0H A;  5T5I D;  2E2H A;  4AZD A;  2JA6 A;  3O5A A;  1OGY A;  1TWF A;  1PQH A;  3DMR A;  1KQG A;  4CRY G;  1EU1 A;  3GTJ A;  2VPX A;  4KLN A;  1TMO A;  4CRZ A;  4DMR A;  3HKZ A;  2NAP A;  1DMR A;  4GA6 A;  1K83 A;  1CZ4 A;  4GA5 A;  1Y1V A;  2VPY A;  3OUG A;  1TWH A;  5B6C A;  1QCS A;  1AW8 B;  4AAY A;  3TM7 B;  3GTL A;  2WAQ A;  1E18 A;  1I50 A;  2WB1 A;  3HU2 A;  5FTM A;  1SIW A;  1Y4Z A;  2VPW A;  3IR6 A;  1TWG A;  2PJH B;  1UHE A;  4D7Z B;  3IR5 A;  4QIW A;  1PPY A;  1PYU B;  2YU9 A;  3GTQ A;  1PQE A;  1AA6 A;  5DYI A;  1PT1 A;  2JIR A;  1R9T A;  1PT0 A;  2JA5 A;  3FKI A;  2PMZ A;  2KI8 A;  1FDI A;  2VPZ A;  3QQ7 A;  5C18 A;  3PLX B;  1PYQ A;  2JIO A;  2JIM A;  2B63 A;  5FTK A;  3TIW A;  4KOD A;  1Q16 A;  1UHD A;  4KO8 A;  1FDO A;  2NVX A;  1QDN A;  3GTK A;  2V3V A;  4C2M A;  1IW7 D;  1WCM A;  1I3Q A;  5C1B A;  1G8K A;  1VC3 B;  5FTJ A;  4KDL A;  1S3S A;  1CZ5 A;  2R7Z A;  1E61 A;  2V45 A;  3HU3 A;  1TWC A;  1CR5 A;  1TWA A;  1PQF A;  1E32 A;  3H0G A;  3CF2 A;  5DYG A;  3GTM A;  4AOK B;  3IR7 A;  2JIP A;  3QC8 A;  2DMR A;  1SFO A;  3QQ8 A;  4AON B;  2EEO B;  2NYA A;  4RV0 A;  1E60 A;  2NVY A;  2R93 A;  1R27 A;  1YLE A;  1WLF A;  2VUM A;  5FTL A;  2E2I A;  2Y0S A;  4KDI A;  1Y5I A;  3QWZ A;  1H5N A;  1R7R A;  5FTN A;  3HU1 A;  3GTO A;  4AYB A;  5T5M D;  1E5V A;  2JIQ A;  1Y1W A;  3CQZ A;  1DMS A;  3GTG A;  1G8J A;  2IV2 X;  2JA7 A;  2R92 A;  3ML1 A;  5EPP A;  5GLF A;  4CS0 A; 
#chains in the Genus database with same CATH topology
 1SMY D;  2C45 A;  1KQF A;  3GTP A;  2A6H D;  2E7Z A;  1H0H A;  5T5I D;  2E2H A;  5H4U A;  4AZD A;  2JA6 A;  3SUM A;  2HCZ X;  3O5A A;  2G6G A;  1OGY A;  4JJO A;  1TWF A;  1PQH A;  1L8F A;  3DMR A;  4CRY G;  1KQG A;  1EU1 A;  3GTJ A;  2VPX A;  5GM9 A;  4KLN A;  1TMO A;  4FFT A;  5GLX A;  4CRZ A;  3HKZ A;  2NAP A;  1DMR A;  4GA6 A;  4DMR A;  4FG2 A;  1K83 A;  1CZ4 A;  4GA5 A;  1Y1V A;  2VPY A;  3OUG A;  1TWH A;  3SUJ A;  5B6C A;  1QCS A;  1WC2 A;  1AW8 B;  3SUK A;  4AAY A;  4JS7 A;  3TM7 B;  3GTL A;  3X2N A;  3M3G A;  2WAQ A;  1E18 A;  1I50 A;  4JP6 A;  2WB1 A;  1BW4 A;  3HU2 A;  5FTM A;  1SIW A;  5GLY A;  3X2P A;  2G5D A;  2A69 D;  1Y4Z A;  2VPW A;  3IR6 A;  1TWG A;  2PJH B;  1UHE A;  2BH0 A;  1ZC1 A;  4D7Z B;  4JCW A;  3IR5 A;  4QIW A;  1HD5 A;  1PPY A;  1PYU B;  2YU9 A;  4NOH A;  3GTQ A;  1PQE A;  1AA6 A;  5DYI A;  3X2K A;  4ZM7 A;  1PT1 A;  2CW0 D;  2A68 D;  2JIR A;  1R9T A;  3X2I A;  2GAE A;  1PT0 A;  3SUL A;  3FKI A;  2JA5 A;  3X2M A;  2AE0 X;  2PMZ A;  2KI8 A;  3CZB A;  1FDI A;  2VPZ A;  3QQ7 A;  5C18 A;  3ENG A;  3PLX B;  3X2L A;  2PJJ A;  1PYQ A;  2JIO A;  2BE5 D;  2JIM A;  2B63 A;  5FTK A;  3TIW A;  4KOD A;  1Q16 A;  1UHD A;  4KO8 A;  2ENG A;  1FDO A;  2A6E D;  2NVX A;  1QDN A;  4ENG A;  2O5J D;  3GTK A;  2V3V A;  4C2M A;  1IW7 D;  1OA7 A;  1WCM A;  1I3Q A;  5C1B A;  1G8K A;  1VC3 B;  5FTJ A;  4KDL A;  1S3S A;  1CZ5 A;  2R7Z A;  3X2G A;  1E61 A;  2V45 A;  3HU3 A;  1TWC A;  1CR5 A;  1TWA A;  1PQF A;  1E32 A;  3D30 A;  3CF2 A;  3H0G A;  5DYG A;  3X2J A;  2PNW A;  2KQA A;  3GTM A;  4AOK B;  3IR7 A;  2JIP A;  3QC8 A;  2DMR A;  1SFO A;  4FER A;  4L48 A;  3QQ8 A;  1ZYR D;  4AON B;  2EEO B;  2NYA A;  4RV0 A;  1YNJ D;  1E60 A;  3X2H A;  1BW3 A;  1N10 A;  2NVY A;  2R93 A;  1R27 A;  1YLE A;  5GLF A;  1WLF A;  2VUM A;  2PI8 A;  5FTL A;  2E2I A;  2Y0S A;  4KDI A;  1Y5I A;  3QWZ A;  4FG4 A;  1H5N A;  1R7R A;  5FTN A;  3HU1 A;  3GTO A;  4AYB A;  1YNN D;  5T5M D;  1E5V A;  2JIQ A;  1OA9 A;  1Y1W A;  3X2O A;  3CQZ A;  1DMS A;  4JP7 A;  3GTG A;  1G8J A;  2IV2 X;  2JA7 A;  2R92 A;  3ML1 A;  2PIC A;  5EPP A;  2YUJ A;  4CS0 A;  4AVR A; 
#chains in the Genus database with same CATH homology
 1SMY D;  2C45 A;  1KQF A;  3GTP A;  2A6H D;  2E7Z A;  1H0H A;  5T5I D;  2E2H A;  4AZD A;  2JA6 A;  3O5A A;  2G6G A;  1OGY A;  1TWF A;  1PQH A;  3DMR A;  1KQG A;  4CRY G;  1EU1 A;  3GTJ A;  2VPX A;  4KLN A;  1TMO A;  4CRZ A;  4DMR A;  3HKZ A;  2NAP A;  1DMR A;  4GA6 A;  1K83 A;  1CZ4 A;  4GA5 A;  1Y1V A;  2VPY A;  3OUG A;  1TWH A;  5B6C A;  1QCS A;  1AW8 B;  4AAY A;  3TM7 B;  3GTL A;  2WAQ A;  1E18 A;  1I50 A;  2WB1 A;  3HU2 A;  5FTM A;  1SIW A;  2G5D A;  2A69 D;  1Y4Z A;  2VPW A;  3IR6 A;  1TWG A;  2PJH B;  1UHE A;  1ZC1 A;  4D7Z B;  3IR5 A;  4QIW A;  1PPY A;  1PYU B;  2YU9 A;  4NOH A;  3GTQ A;  1PQE A;  1AA6 A;  5DYI A;  1PT1 A;  2CW0 D;  2A68 D;  2JIR A;  1R9T A;  2GAE A;  1PT0 A;  2JA5 A;  3FKI A;  2AE0 X;  2PMZ A;  2KI8 A;  3CZB A;  1FDI A;  2VPZ A;  3QQ7 A;  5C18 A;  3PLX B;  2PJJ A;  1PYQ A;  2JIO A;  2BE5 D;  2JIM A;  2B63 A;  5FTK A;  3TIW A;  4KOD A;  1Q16 A;  1UHD A;  4KO8 A;  1FDO A;  2A6E D;  2NVX A;  1QDN A;  2O5J D;  3GTK A;  2V3V A;  4C2M A;  1IW7 D;  1WCM A;  1I3Q A;  5C1B A;  1G8K A;  1VC3 B;  5FTJ A;  4KDL A;  1S3S A;  1CZ5 A;  2R7Z A;  1E61 A;  2V45 A;  3HU3 A;  1TWC A;  1CR5 A;  1TWA A;  1PQF A;  1E32 A;  3H0G A;  3CF2 A;  5DYG A;  2PNW A;  3GTM A;  4AOK B;  3IR7 A;  2JIP A;  3QC8 A;  2DMR A;  1SFO A;  3QQ8 A;  1ZYR D;  4AON B;  2EEO B;  2NYA A;  4RV0 A;  1YNJ D;  1E60 A;  2NVY A;  2R93 A;  1R27 A;  1YLE A;  5GLF A;  1WLF A;  2VUM A;  2PI8 A;  5FTL A;  2E2I A;  2Y0S A;  4KDI A;  1Y5I A;  3QWZ A;  1H5N A;  1R7R A;  5FTN A;  3HU1 A;  3GTO A;  4AYB A;  1YNN D;  5T5M D;  1E5V A;  2JIQ A;  1Y1W A;  3CQZ A;  1DMS A;  3GTG A;  1G8J A;  2IV2 X;  2JA7 A;  2R92 A;  3ML1 A;  2PIC A;  5EPP A;  2YUJ A;  4CS0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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