1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords Aspartate 1-decarboxylase
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
1G8KA 1H0HA 1PYUB 2R93A 4KLNA 3IR7A 3OUGA 1AA6A 2NVXA 5EPPA 1K83A 1YLEA 2V3VA 4GA5A 1TWCA 1H5NA 1Q16A 5DYGA 3GTQA 4CRZA 2E7ZA 2WAQA 5FTNA 1KQFA 2V45A 2PMZA 1G8JA 1PQHA 1R27A 1Y1VA 4KODA 4KO8A 1PPYA 1E60A 2DMRA 1TMOA 2JIOA 1EU1A 2PJHB 2WB1A 1TWFA 3O5AA 2JA6A 3H0GA 4QIWA 2JA5A 2JIRA 3QQ8A 1FDOA 4AZDA 1KQGA 1E18A 2R7ZA 3CF2A 3HKZA 3DMRA 1VC3B 2VPZA 2NVYA 2R92A 3ML1A 3GTPA 1DMRA 3IR6A 1I3QA 4RV0A 1I50A 1SIWA 1E61A 1SFOA 5FTLA 5GLFA 5C18A 3GTMA 2KI8A 5FTKA 1PT0A 2JA7A 3TIWA 1TWAA 2C45A 1TWHA 1UHDA 1CR5A 1WLFA 1DMSA 3GTLA 1Y5IA 2NYAA 4AYBA 1PYQA 4KDIA 1CZ5A 1UHEA 3FKIA 1IW7D 4AAYA 3GTKA 3PLXB 4DMRA 4KDLA 3HU3A 1CZ4A 1TWGA 1E5VA 2VPXA 3GTOA 4C2MA 1R9TA 5DYIA 4AONB 2VUMA 2NAPA 5C1BA 5T5ID 3TM7B 1S3SA 2VPYA 1PQEA 2B63A 3QQ7A 5FTMA 1WCMA 3HU1A 1QDNA 1E32A 2IV2X 4D7ZB 2EEOB 3GTJA 2E2HA 5B6CA 3IR5A 3HU2A 4GA6A 3GTGA 2YU9A 2JIQA 1QCSA 1PT1A 1Y4ZA 2E2IA 1OGYA 1PQFA 5FTJA 1AW8B 5T5MD 2VPWA 1Y1WA 2Y0SA 2JIPA 4CRYG 3QC8A 2JIMA 3CQZA 4AOKB 1R7RA 1FDIA 3QWZA 4CS0A
chains in the Genus database with same CATH superfamily
1G8KA 1H0HA 1PYUB 2R93A 3X2LA 4KLNA 3IR7A 3OUGA 1AA6A 2NVXA 1YNJD 2GAEA 5EPPA 3X2OA 1K83A 2A68D 4FFTA 2A69D 1YLEA 3X2GA 2PICA 2V3VA 1TWCA 4GA5A 2BH0A 1H5NA 4FG2A 1Q16A 5DYGA 1ZC1A 3GTQA 4CRZA 2E7ZA 2WAQA 1WC2A 5FTNA 3X2NA 1KQFA 2V45A 2HCZX 2PMZA 1G8JA 1PQHA 1R27A 1Y1VA 2A6ED 4KO8A 1PPYA 1E60A 4KODA 2DMRA 1TMOA 2JIOA 4JP7A 1EU1A 1YNND 2PJHB 2WB1A 3ENGA 1TWFA 3O5AA 2JA6A 3H0GA 4QIWA 2KQAA 2JA5A 5GM9A 2JIRA 3QQ8A 1FDOA 4AZDA 1KQGA 1E18A 2R7ZA 3CF2A 3HKZA 3DMRA 3X2HA 1BW3A 2G5DA 1VC3B 2VPZA 2NVYA 4JP6A 2R92A 4JCWA 3ML1A 3GTPA 1DMRA 3IR6A 3X2IA 1I3QA 4RV0A 1I50A 1SIWA 1E61A 1ZYRD 1SFOA 5FTLA 1SMYD 5GLFA 5C18A 3GTMA 1BW4A 2KI8A 5FTKA 1PT0A 2JA7A 3TIWA 1TWAA 1L8FA 2A6HD 2C45A 1TWHA 1UHDA 1CR5A 1OA7A 1DMSA 1WLFA 2AE0X 3GTLA 1Y5IA 1HD5A 2NYAA 4AYBA 1PYQA 4KDIA 1CZ5A 1UHEA 3FKIA 1IW7D 4AAYA 2PI8A 3GTKA 2ENGA 3PLXB 1N10A 4KDLA 4DMRA 3HU3A 3CZBA 1CZ4A 1TWGA 1E5VA 2VPXA 3X2MA 3GTOA 4C2MA 1R9TA 5DYIA 4AONB 2VUMA 2NAPA 5C1BA 5T5ID 3TM7B 2YUJA 1S3SA 2VPYA 3M3GA 2CW0D 1PQEA 4AVRA 2B63A 3QQ7A 3D30A 5FTMA 1WCMA 3X2JA 3HU1A 1QDNA 1E32A 2IV2X 4D7ZB 2EEOB 3GTJA 2E2HA 5B6CA 2PJJA 3IR5A 3HU2A 4GA6A 3GTGA 2YU9A 2JIQA 4FG4A 2G6GA 1QCSA 1PT1A 1Y4ZA 4FERA 3SUJA 2BE5D 4JJOA 2E2IA 1OA9A 1OGYA 1PQFA 3SULA 2PNWA 4ENGA 4JS7A 5FTJA 1AW8B 5T5MD 2VPWA 3X2PA 1Y1WA 2Y0SA 2JIPA 3SUMA 3QC8A 5GLYA 4CRYG 4L48A 3SUKA 3X2KA 2JIMA 3CQZA 4AOKB 2O5JD 1R7RA 5GLXA 1FDIA 5H4UA 3QWZA 4NOHA 4ZM7A 4CS0A
chains in the Genus database with same CATH topology
1G8KA 1H0HA 1PYUB 2R93A 4KLNA 3IR7A 3OUGA 1AA6A 2NVXA 1YNJD 2GAEA 5EPPA 1K83A 2A68D 2A69D 1YLEA 2PICA 2V3VA 1TWCA 4GA5A 1H5NA 1Q16A 5DYGA 1ZC1A 3GTQA 4CRZA 2E7ZA 2WAQA 5FTNA 1KQFA 2V45A 2PMZA 1G8JA 1PQHA 1R27A 1Y1VA 2A6ED 4KO8A 1PPYA 1E60A 4KODA 2DMRA 1TMOA 2JIOA 1EU1A 1YNND 2PJHB 2WB1A 1TWFA 3O5AA 2JA6A 3H0GA 4QIWA 2JA5A 2JIRA 3QQ8A 1FDOA 4AZDA 1KQGA 1E18A 2R7ZA 3CF2A 3HKZA 3DMRA 2G5DA 1VC3B 2VPZA 2NVYA 2R92A 3ML1A 3GTPA 1DMRA 3IR6A 1I3QA 4RV0A 1I50A 1SIWA 1E61A 1ZYRD 1SFOA 5FTLA 1SMYD 5GLFA 5C18A 3GTMA 2KI8A 5FTKA 1PT0A 2JA7A 3TIWA 1TWAA 2A6HD 2C45A 1TWHA 1UHDA 1CR5A 1WLFA 1DMSA 2AE0X 3GTLA 1Y5IA 2NYAA 4AYBA 1PYQA 4KDIA 1CZ5A 1UHEA 3FKIA 1IW7D 4AAYA 2PI8A 3GTKA 3PLXB 4DMRA 4KDLA 3HU3A 3CZBA 1CZ4A 1TWGA 1E5VA 2VPXA 3GTOA 4C2MA 1R9TA 5DYIA 4AONB 2VUMA 2NAPA 5C1BA 5T5ID 3TM7B 2YUJA 1S3SA 2VPYA 2CW0D 1PQEA 2B63A 3QQ7A 5FTMA 1WCMA 3HU1A 1QDNA 1E32A 2IV2X 4D7ZB 2EEOB 3GTJA 2E2HA 5B6CA 2PJJA 3IR5A 3HU2A 4GA6A 3GTGA 2YU9A 2JIQA 2G6GA 1QCSA 1PT1A 1Y4ZA 2BE5D 2E2IA 1OGYA 1PQFA 2PNWA 5FTJA 1AW8B 5T5MD 2VPWA 1Y1WA 2Y0SA 2JIPA 4CRYG 3QC8A 2JIMA 3CQZA 4AOKB 2O5JD 1R7RA 1FDIA 3QWZA 4NOHA 4CS0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G8K A;  1H0H A;  1PYU B;  2R93 A;  4KLN A;  3IR7 A;  3OUG A;  1AA6 A;  2NVX A;  5EPP A;  1K83 A;  1YLE A;  2V3V A;  4GA5 A;  1TWC A;  1H5N A;  1Q16 A;  5DYG A;  3GTQ A;  4CRZ A;  2E7Z A;  2WAQ A;  5FTN A;  1KQF A;  2V45 A;  2PMZ A;  1G8J A;  1PQH A;  1R27 A;  1Y1V A;  4KOD A;  4KO8 A;  1PPY A;  1E60 A;  2DMR A;  1TMO A;  2JIO A;  1EU1 A;  2PJH B;  2WB1 A;  1TWF A;  3O5A A;  2JA6 A;  3H0G A;  4QIW A;  2JA5 A;  2JIR A;  3QQ8 A;  1FDO A;  4AZD A;  1KQG A;  1E18 A;  2R7Z A;  3CF2 A;  3HKZ A;  3DMR A;  1VC3 B;  2VPZ A;  2NVY A;  2R92 A;  3ML1 A;  3GTP A;  1DMR A;  3IR6 A;  1I3Q A;  4RV0 A;  1I50 A;  1SIW A;  1E61 A;  1SFO A;  5FTL A;  5GLF A;  5C18 A;  3GTM A;  2KI8 A;  5FTK A;  1PT0 A;  2JA7 A;  3TIW A;  1TWA A;  2C45 A;  1TWH A;  1UHD A;  1CR5 A;  1WLF A;  1DMS A;  3GTL A;  1Y5I A;  2NYA A;  4AYB A;  1PYQ A;  4KDI A;  1CZ5 A;  1UHE A;  3FKI A;  1IW7 D;  4AAY A;  3GTK A;  3PLX B;  4DMR A;  4KDL A;  3HU3 A;  1CZ4 A;  1TWG A;  1E5V A;  2VPX A;  3GTO A;  4C2M A;  1R9T A;  5DYI A;  4AON B;  2VUM A;  2NAP A;  5C1B A;  5T5I D;  3TM7 B;  1S3S A;  2VPY A;  1PQE A;  2B63 A;  3QQ7 A;  5FTM A;  1WCM A;  3HU1 A;  1QDN A;  1E32 A;  2IV2 X;  4D7Z B;  2EEO B;  3GTJ A;  2E2H A;  5B6C A;  3IR5 A;  3HU2 A;  4GA6 A;  3GTG A;  2YU9 A;  2JIQ A;  1QCS A;  1PT1 A;  1Y4Z A;  2E2I A;  1OGY A;  1PQF A;  5FTJ A;  1AW8 B;  5T5M D;  2VPW A;  1Y1W A;  2Y0S A;  2JIP A;  4CRY G;  3QC8 A;  2JIM A;  3CQZ A;  4AOK B;  1R7R A;  1FDI A;  3QWZ A;  4CS0 A; 
#chains in the Genus database with same CATH topology
 1G8K A;  1H0H A;  1PYU B;  2R93 A;  3X2L A;  4KLN A;  3IR7 A;  3OUG A;  1AA6 A;  2NVX A;  1YNJ D;  2GAE A;  5EPP A;  3X2O A;  1K83 A;  2A68 D;  4FFT A;  2A69 D;  1YLE A;  3X2G A;  2PIC A;  2V3V A;  1TWC A;  4GA5 A;  2BH0 A;  1H5N A;  4FG2 A;  1Q16 A;  5DYG A;  1ZC1 A;  3GTQ A;  4CRZ A;  2E7Z A;  2WAQ A;  1WC2 A;  5FTN A;  3X2N A;  1KQF A;  2V45 A;  2HCZ X;  2PMZ A;  1G8J A;  1PQH A;  1R27 A;  1Y1V A;  2A6E D;  4KO8 A;  1PPY A;  1E60 A;  4KOD A;  2DMR A;  1TMO A;  2JIO A;  4JP7 A;  1EU1 A;  1YNN D;  2PJH B;  2WB1 A;  3ENG A;  1TWF A;  3O5A A;  2JA6 A;  3H0G A;  4QIW A;  2KQA A;  2JA5 A;  5GM9 A;  2JIR A;  3QQ8 A;  1FDO A;  4AZD A;  1KQG A;  1E18 A;  2R7Z A;  3CF2 A;  3HKZ A;  3DMR A;  3X2H A;  1BW3 A;  2G5D A;  1VC3 B;  2VPZ A;  2NVY A;  4JP6 A;  2R92 A;  4JCW A;  3ML1 A;  3GTP A;  1DMR A;  3IR6 A;  3X2I A;  1I3Q A;  4RV0 A;  1I50 A;  1SIW A;  1E61 A;  1ZYR D;  1SFO A;  5FTL A;  1SMY D;  5GLF A;  5C18 A;  3GTM A;  1BW4 A;  2KI8 A;  5FTK A;  1PT0 A;  2JA7 A;  3TIW A;  1TWA A;  1L8F A;  2A6H D;  2C45 A;  1TWH A;  1UHD A;  1CR5 A;  1OA7 A;  1DMS A;  1WLF A;  2AE0 X;  3GTL A;  1Y5I A;  1HD5 A;  2NYA A;  4AYB A;  1PYQ A;  4KDI A;  1CZ5 A;  1UHE A;  3FKI A;  1IW7 D;  4AAY A;  2PI8 A;  3GTK A;  2ENG A;  3PLX B;  1N10 A;  4KDL A;  4DMR A;  3HU3 A;  3CZB A;  1CZ4 A;  1TWG A;  1E5V A;  2VPX A;  3X2M A;  3GTO A;  4C2M A;  1R9T A;  5DYI A;  4AON B;  2VUM A;  2NAP A;  5C1B A;  5T5I D;  3TM7 B;  2YUJ A;  1S3S A;  2VPY A;  3M3G A;  2CW0 D;  1PQE A;  4AVR A;  2B63 A;  3QQ7 A;  3D30 A;  5FTM A;  1WCM A;  3X2J A;  3HU1 A;  1QDN A;  1E32 A;  2IV2 X;  4D7Z B;  2EEO B;  3GTJ A;  2E2H A;  5B6C A;  2PJJ A;  3IR5 A;  3HU2 A;  4GA6 A;  3GTG A;  2YU9 A;  2JIQ A;  4FG4 A;  2G6G A;  1QCS A;  1PT1 A;  1Y4Z A;  4FER A;  3SUJ A;  2BE5 D;  4JJO A;  2E2I A;  1OA9 A;  1OGY A;  1PQF A;  3SUL A;  2PNW A;  4ENG A;  4JS7 A;  5FTJ A;  1AW8 B;  5T5M D;  2VPW A;  3X2P A;  1Y1W A;  2Y0S A;  2JIP A;  3SUM A;  3QC8 A;  5GLY A;  4CRY G;  4L48 A;  3SUK A;  3X2K A;  2JIM A;  3CQZ A;  4AOK B;  2O5J D;  1R7R A;  5GLX A;  1FDI A;  5H4U A;  3QWZ A;  4NOH A;  4ZM7 A;  4CS0 A; 
#chains in the Genus database with same CATH homology
 1G8K A;  1H0H A;  1PYU B;  2R93 A;  4KLN A;  3IR7 A;  3OUG A;  1AA6 A;  2NVX A;  1YNJ D;  2GAE A;  5EPP A;  1K83 A;  2A68 D;  2A69 D;  1YLE A;  2PIC A;  2V3V A;  1TWC A;  4GA5 A;  1H5N A;  1Q16 A;  5DYG A;  1ZC1 A;  3GTQ A;  4CRZ A;  2E7Z A;  2WAQ A;  5FTN A;  1KQF A;  2V45 A;  2PMZ A;  1G8J A;  1PQH A;  1R27 A;  1Y1V A;  2A6E D;  4KO8 A;  1PPY A;  1E60 A;  4KOD A;  2DMR A;  1TMO A;  2JIO A;  1EU1 A;  1YNN D;  2PJH B;  2WB1 A;  1TWF A;  3O5A A;  2JA6 A;  3H0G A;  4QIW A;  2JA5 A;  2JIR A;  3QQ8 A;  1FDO A;  4AZD A;  1KQG A;  1E18 A;  2R7Z A;  3CF2 A;  3HKZ A;  3DMR A;  2G5D A;  1VC3 B;  2VPZ A;  2NVY A;  2R92 A;  3ML1 A;  3GTP A;  1DMR A;  3IR6 A;  1I3Q A;  4RV0 A;  1I50 A;  1SIW A;  1E61 A;  1ZYR D;  1SFO A;  5FTL A;  1SMY D;  5GLF A;  5C18 A;  3GTM A;  2KI8 A;  5FTK A;  1PT0 A;  2JA7 A;  3TIW A;  1TWA A;  2A6H D;  2C45 A;  1TWH A;  1UHD A;  1CR5 A;  1WLF A;  1DMS A;  2AE0 X;  3GTL A;  1Y5I A;  2NYA A;  4AYB A;  1PYQ A;  4KDI A;  1CZ5 A;  1UHE A;  3FKI A;  1IW7 D;  4AAY A;  2PI8 A;  3GTK A;  3PLX B;  4DMR A;  4KDL A;  3HU3 A;  3CZB A;  1CZ4 A;  1TWG A;  1E5V A;  2VPX A;  3GTO A;  4C2M A;  1R9T A;  5DYI A;  4AON B;  2VUM A;  2NAP A;  5C1B A;  5T5I D;  3TM7 B;  2YUJ A;  1S3S A;  2VPY A;  2CW0 D;  1PQE A;  2B63 A;  3QQ7 A;  5FTM A;  1WCM A;  3HU1 A;  1QDN A;  1E32 A;  2IV2 X;  4D7Z B;  2EEO B;  3GTJ A;  2E2H A;  5B6C A;  2PJJ A;  3IR5 A;  3HU2 A;  4GA6 A;  3GTG A;  2YU9 A;  2JIQ A;  2G6G A;  1QCS A;  1PT1 A;  1Y4Z A;  2BE5 D;  2E2I A;  1OGY A;  1PQF A;  2PNW A;  5FTJ A;  1AW8 B;  5T5M D;  2VPW A;  1Y1W A;  2Y0S A;  2JIP A;  4CRY G;  3QC8 A;  2JIM A;  3CQZ A;  4AOK B;  2O5J D;  1R7R A;  1FDI A;  3QWZ A;  4NOH A;  4CS0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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