2C45A

Native precursor of pyruvoyl dependent aspartate decarboxylase
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
113
structure length
113
Chain Sequence
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of uncleaved L-aspartate-alpha-decarboxylase from Mycobacterium tuberculosis.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Lyase
molecule keywords Aspartate 1-decarboxylase
total genus 27
structure length 113
sequence length 113
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2005-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2c45A00
1FDOA 1Y4ZA 2PMZA 1QDNA 2B63A 2NAPA 3HU1A 3IR6A 1E18A 1YLEA 2DMRA 3GTMA 3HU2A 1TWGA 4AYBA 1TWAA 3GTOA 2R7ZA 3FKIA 1DMRA 2JIPA 2JIQA 2VPZA 3GTPA 1TWHA 1TWCA 1VC3B 4KDIA 4CRYG 4AZDA 4GA6A 1Y1VA 2NVXA 3GTJA 2E2IA 5DYGA 3CQZA 2E2HA 4KODA 1SIWA 1H0HA 4AONB 3GTGA 2VPWA 4KDLA 1UHDA 2JIRA 1K83A 2JA6A 1TWFA 4RV0A 1WCMA 3TIWA 1IW7D 3IR7A 5EPPA 1H5NA 3IR5A 5DYIA 1TMOA 2VPXA 1PQHA 3OUGA 1EU1A 1R9TA 5C18A 1G8KA 2PJHB 2JA7A 5T5ID 1PQEA 5FTJA 2VPYA 2YU9A 1R27A 3QC8A 4GA5A 1E61A 1R7RA 1E60A 5B6CA 2E7ZA 1Q16A 3ML1A 4KLNA 1CR5A 3CF2A 2NVYA 2C45A 1PYUB 1SFOA 2V45A 3O5AA 2VUMA 3QWZA 4CRZA 5FTKA 1OGYA 1CZ4A 1PPYA 2EEOB 2Y0SA 5C1BA 3GTKA 1E5VA 3HU3A 3H0GA 1UHEA 4DMRA 1DMSA 3PLXB 1PT0A 2V3VA 5FTMA 1KQGA 3GTQA 5T5MD 3HKZA 2JIOA 2WB1A 1KQFA 1G8JA 1Y1WA 4AOKB 1E32A 1CZ5A 1WLFA 5GLFA 1AW8B 1PYQA 3QQ8A 2JA5A 2WAQA 4D7ZB 2KI8A 1Y5IA 3TM7B 4AAYA 5FTNA 1QCSA 2R93A 2R92A 1PQFA 1I3QA 1PT1A 4CS0A 1AA6A 4C2MA 5FTLA 1I50A 4QIWA 1S3SA 4KO8A 3DMRA 2IV2X 2JIMA 3GTLA 1FDIA 2NYAA 3QQ7A
chains in the Genus database with same CATH superfamily
1FDOA 2PJJA 1Y4ZA 2PMZA 4JJOA 2A6ED 4JP7A 1QDNA 5GLXA 2B63A 2NAPA 3HU1A 3IR6A 1E18A 3SUJA 3X2GA 2ENGA 1YLEA 2DMRA 2KQAA 3X2KA 3GTMA 3HU2A 3CZBA 1TWGA 4AYBA 1TWAA 3GTOA 2PNWA 2CW0D 2R7ZA 1DMRA 2JIPA 2JIQA 3FKIA 2VPZA 3GTPA 2AE0X 1TWHA 1TWCA 1WC2A 1VC3B 4FERA 4KDIA 4CRYG 1ZYRD 4AZDA 4FG2A 4GA6A 3X2LA 1Y1VA 4ENGA 2NVXA 3GTJA 4ZM7A 2E2IA 5DYGA 3CQZA 2E2HA 4KODA 1SIWA 1H0HA 3X2MA 4AONB 3GTGA 4FFTA 5H4UA 2VPWA 4KDLA 1UHDA 2JIRA 1K83A 2JA6A 1TWFA 4RV0A 1WCMA 2A6HD 3X2IA 2A69D 3TIWA 1IW7D 2GAEA 3IR7A 1SMYD 2G6GA 5EPPA 3SUMA 1OA7A 1H5NA 3IR5A 5DYIA 1TMOA 2VPXA 1HD5A 1PQHA 3OUGA 1EU1A 1R9TA 4FG4A 5C18A 1G8KA 2PJHB 2JA7A 2G5DA 2BE5D 4JP6A 5GM9A 5T5ID 1PQEA 5FTJA 2VPYA 2YU9A 1R27A 3X2OA 3QC8A 4GA5A 4NOHA 1E61A 1R7RA 1YNND 2A68D 1N10A 1E60A 5B6CA 2E7ZA 1Q16A 3ML1A 4KLNA 1CR5A 3CF2A 3X2NA 3X2PA 2NVYA 3ENGA 3SULA 2C45A 1PYUB 1SFOA 2V45A 3O5AA 2VUMA 3QWZA 4CRZA 5FTKA 1ZC1A 1OGYA 1BW3A 1CZ4A 1PPYA 3D30A 2EEOB 4JCWA 4JS7A 2Y0SA 5C1BA 3GTKA 3SUKA 1E5VA 5GLYA 2YUJA 3HU3A 3H0GA 1UHEA 3X2JA 4DMRA 4L48A 1DMSA 3PLXB 1PT0A 2PICA 2V3VA 5FTMA 1KQGA 3GTQA 5T5MD 3HKZA 2JIOA 2WB1A 1KQFA 1G8JA 1YNJD 1Y1WA 2PI8A 1E32A 4AOKB 1L8FA 1WLFA 1CZ5A 5GLFA 1AW8B 1PYQA 3QQ8A 3X2HA 2JA5A 2WAQA 2BH0A 4D7ZB 2KI8A 2NYAA 3TM7B 4AAYA 5FTNA 1OA9A 1QCSA 2O5JD 2R93A 2R92A 1PQFA 4AVRA 1I3QA 1PT1A 4CS0A 1AA6A 1BW4A 4C2MA 5FTLA 1I50A 4QIWA 1S3SA 4KO8A 2HCZX 3DMRA 2JIMA 2IV2X 3GTLA 3M3GA 1FDIA 1Y5IA 3QQ7A
chains in the Genus database with same CATH topology
1FDOA 2PJJA 1Y4ZA 2PMZA 2A6ED 1QDNA 2B63A 2NAPA 3HU1A 3IR6A 1E18A 1YLEA 2DMRA 3GTMA 3HU2A 3CZBA 1TWGA 4AYBA 1TWAA 3GTOA 2PNWA 2CW0D 2R7ZA 1DMRA 2JIPA 2JIQA 3FKIA 2VPZA 3GTPA 2AE0X 1TWHA 1TWCA 1VC3B 4KDIA 4CRYG 1ZYRD 4AZDA 4GA6A 1Y1VA 2NVXA 3GTJA 2E2IA 5DYGA 3CQZA 2E2HA 4KODA 1SIWA 1H0HA 4AONB 3GTGA 2VPWA 4KDLA 1UHDA 2JIRA 1K83A 2JA6A 1TWFA 4RV0A 1WCMA 2A6HD 2A69D 3TIWA 1IW7D 2GAEA 3IR7A 1SMYD 2G6GA 5EPPA 1H5NA 3IR5A 5DYIA 1TMOA 2VPXA 1PQHA 3OUGA 1EU1A 1R9TA 5C18A 1G8KA 2PJHB 2JA7A 2G5DA 2BE5D 5T5ID 1PQEA 5FTJA 2VPYA 2YU9A 1R27A 3QC8A 4GA5A 4NOHA 1E61A 1R7RA 1YNND 2A68D 1E60A 5B6CA 2E7ZA 1Q16A 3ML1A 4KLNA 1CR5A 3CF2A 2NVYA 2C45A 1PYUB 1SFOA 2V45A 3O5AA 2VUMA 3QWZA 4CRZA 5FTKA 1ZC1A 1OGYA 1CZ4A 1PPYA 2EEOB 2Y0SA 5C1BA 3GTKA 1E5VA 2YUJA 3HU3A 3H0GA 1UHEA 4DMRA 1DMSA 3PLXB 1PT0A 2PICA 2V3VA 5FTMA 1KQGA 3GTQA 5T5MD 3HKZA 2JIOA 2WB1A 1KQFA 1G8JA 1YNJD 1Y1WA 2PI8A 1E32A 4AOKB 1CZ5A 1WLFA 5GLFA 1AW8B 1PYQA 3QQ8A 2JA5A 2WAQA 4D7ZB 2KI8A 1Y5IA 3TM7B 4AAYA 5FTNA 1QCSA 2O5JD 2R93A 2R92A 1PQFA 1I3QA 1PT1A 4CS0A 1AA6A 4C2MA 5FTLA 1I50A 4QIWA 1S3SA 4KO8A 3DMRA 2IV2X 2JIMA 3GTLA 1FDIA 2NYAA 3QQ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FDO A;  1Y4Z A;  2PMZ A;  1QDN A;  2B63 A;  2NAP A;  3HU1 A;  3IR6 A;  1E18 A;  1YLE A;  2DMR A;  3GTM A;  3HU2 A;  1TWG A;  4AYB A;  1TWA A;  3GTO A;  2R7Z A;  3FKI A;  1DMR A;  2JIP A;  2JIQ A;  2VPZ A;  3GTP A;  1TWH A;  1TWC A;  1VC3 B;  4KDI A;  4CRY G;  4AZD A;  4GA6 A;  1Y1V A;  2NVX A;  3GTJ A;  2E2I A;  5DYG A;  3CQZ A;  2E2H A;  4KOD A;  1SIW A;  1H0H A;  4AON B;  3GTG A;  2VPW A;  4KDL A;  1UHD A;  2JIR A;  1K83 A;  2JA6 A;  1TWF A;  4RV0 A;  1WCM A;  3TIW A;  1IW7 D;  3IR7 A;  5EPP A;  1H5N A;  3IR5 A;  5DYI A;  1TMO A;  2VPX A;  1PQH A;  3OUG A;  1EU1 A;  1R9T A;  5C18 A;  1G8K A;  2PJH B;  2JA7 A;  5T5I D;  1PQE A;  5FTJ A;  2VPY A;  2YU9 A;  1R27 A;  3QC8 A;  4GA5 A;  1E61 A;  1R7R A;  1E60 A;  5B6C A;  2E7Z A;  1Q16 A;  3ML1 A;  4KLN A;  1CR5 A;  3CF2 A;  2NVY A;  2C45 A;  1PYU B;  1SFO A;  2V45 A;  3O5A A;  2VUM A;  3QWZ A;  4CRZ A;  5FTK A;  1OGY A;  1CZ4 A;  1PPY A;  2EEO B;  2Y0S A;  5C1B A;  3GTK A;  1E5V A;  3HU3 A;  3H0G A;  1UHE A;  4DMR A;  1DMS A;  3PLX B;  1PT0 A;  2V3V A;  5FTM A;  1KQG A;  3GTQ A;  5T5M D;  3HKZ A;  2JIO A;  2WB1 A;  1KQF A;  1G8J A;  1Y1W A;  4AOK B;  1E32 A;  1CZ5 A;  1WLF A;  5GLF A;  1AW8 B;  1PYQ A;  3QQ8 A;  2JA5 A;  2WAQ A;  4D7Z B;  2KI8 A;  1Y5I A;  3TM7 B;  4AAY A;  5FTN A;  1QCS A;  2R93 A;  2R92 A;  1PQF A;  1I3Q A;  1PT1 A;  4CS0 A;  1AA6 A;  4C2M A;  5FTL A;  1I50 A;  4QIW A;  1S3S A;  4KO8 A;  3DMR A;  2IV2 X;  2JIM A;  3GTL A;  1FDI A;  2NYA A;  3QQ7 A; 
#chains in the Genus database with same CATH topology
 1FDO A;  2PJJ A;  1Y4Z A;  2PMZ A;  4JJO A;  2A6E D;  4JP7 A;  1QDN A;  5GLX A;  2B63 A;  2NAP A;  3HU1 A;  3IR6 A;  1E18 A;  3SUJ A;  3X2G A;  2ENG A;  1YLE A;  2DMR A;  2KQA A;  3X2K A;  3GTM A;  3HU2 A;  3CZB A;  1TWG A;  4AYB A;  1TWA A;  3GTO A;  2PNW A;  2CW0 D;  2R7Z A;  1DMR A;  2JIP A;  2JIQ A;  3FKI A;  2VPZ A;  3GTP A;  2AE0 X;  1TWH A;  1TWC A;  1WC2 A;  1VC3 B;  4FER A;  4KDI A;  4CRY G;  1ZYR D;  4AZD A;  4FG2 A;  4GA6 A;  3X2L A;  1Y1V A;  4ENG A;  2NVX A;  3GTJ A;  4ZM7 A;  2E2I A;  5DYG A;  3CQZ A;  2E2H A;  4KOD A;  1SIW A;  1H0H A;  3X2M A;  4AON B;  3GTG A;  4FFT A;  5H4U A;  2VPW A;  4KDL A;  1UHD A;  2JIR A;  1K83 A;  2JA6 A;  1TWF A;  4RV0 A;  1WCM A;  2A6H D;  3X2I A;  2A69 D;  3TIW A;  1IW7 D;  2GAE A;  3IR7 A;  1SMY D;  2G6G A;  5EPP A;  3SUM A;  1OA7 A;  1H5N A;  3IR5 A;  5DYI A;  1TMO A;  2VPX A;  1HD5 A;  1PQH A;  3OUG A;  1EU1 A;  1R9T A;  4FG4 A;  5C18 A;  1G8K A;  2PJH B;  2JA7 A;  2G5D A;  2BE5 D;  4JP6 A;  5GM9 A;  5T5I D;  1PQE A;  5FTJ A;  2VPY A;  2YU9 A;  1R27 A;  3X2O A;  3QC8 A;  4GA5 A;  4NOH A;  1E61 A;  1R7R A;  1YNN D;  2A68 D;  1N10 A;  1E60 A;  5B6C A;  2E7Z A;  1Q16 A;  3ML1 A;  4KLN A;  1CR5 A;  3CF2 A;  3X2N A;  3X2P A;  2NVY A;  3ENG A;  3SUL A;  2C45 A;  1PYU B;  1SFO A;  2V45 A;  3O5A A;  2VUM A;  3QWZ A;  4CRZ A;  5FTK A;  1ZC1 A;  1OGY A;  1BW3 A;  1CZ4 A;  1PPY A;  3D30 A;  2EEO B;  4JCW A;  4JS7 A;  2Y0S A;  5C1B A;  3GTK A;  3SUK A;  1E5V A;  5GLY A;  2YUJ A;  3HU3 A;  3H0G A;  1UHE A;  3X2J A;  4DMR A;  4L48 A;  1DMS A;  3PLX B;  1PT0 A;  2PIC A;  2V3V A;  5FTM A;  1KQG A;  3GTQ A;  5T5M D;  3HKZ A;  2JIO A;  2WB1 A;  1KQF A;  1G8J A;  1YNJ D;  1Y1W A;  2PI8 A;  1E32 A;  4AOK B;  1L8F A;  1WLF A;  1CZ5 A;  5GLF A;  1AW8 B;  1PYQ A;  3QQ8 A;  3X2H A;  2JA5 A;  2WAQ A;  2BH0 A;  4D7Z B;  2KI8 A;  2NYA A;  3TM7 B;  4AAY A;  5FTN A;  1OA9 A;  1QCS A;  2O5J D;  2R93 A;  2R92 A;  1PQF A;  4AVR A;  1I3Q A;  1PT1 A;  4CS0 A;  1AA6 A;  1BW4 A;  4C2M A;  5FTL A;  1I50 A;  4QIW A;  1S3S A;  4KO8 A;  2HCZ X;  3DMR A;  2JIM A;  2IV2 X;  3GTL A;  3M3G A;  1FDI A;  1Y5I A;  3QQ7 A; 
#chains in the Genus database with same CATH homology
 1FDO A;  2PJJ A;  1Y4Z A;  2PMZ A;  2A6E D;  1QDN A;  2B63 A;  2NAP A;  3HU1 A;  3IR6 A;  1E18 A;  1YLE A;  2DMR A;  3GTM A;  3HU2 A;  3CZB A;  1TWG A;  4AYB A;  1TWA A;  3GTO A;  2PNW A;  2CW0 D;  2R7Z A;  1DMR A;  2JIP A;  2JIQ A;  3FKI A;  2VPZ A;  3GTP A;  2AE0 X;  1TWH A;  1TWC A;  1VC3 B;  4KDI A;  4CRY G;  1ZYR D;  4AZD A;  4GA6 A;  1Y1V A;  2NVX A;  3GTJ A;  2E2I A;  5DYG A;  3CQZ A;  2E2H A;  4KOD A;  1SIW A;  1H0H A;  4AON B;  3GTG A;  2VPW A;  4KDL A;  1UHD A;  2JIR A;  1K83 A;  2JA6 A;  1TWF A;  4RV0 A;  1WCM A;  2A6H D;  2A69 D;  3TIW A;  1IW7 D;  2GAE A;  3IR7 A;  1SMY D;  2G6G A;  5EPP A;  1H5N A;  3IR5 A;  5DYI A;  1TMO A;  2VPX A;  1PQH A;  3OUG A;  1EU1 A;  1R9T A;  5C18 A;  1G8K A;  2PJH B;  2JA7 A;  2G5D A;  2BE5 D;  5T5I D;  1PQE A;  5FTJ A;  2VPY A;  2YU9 A;  1R27 A;  3QC8 A;  4GA5 A;  4NOH A;  1E61 A;  1R7R A;  1YNN D;  2A68 D;  1E60 A;  5B6C A;  2E7Z A;  1Q16 A;  3ML1 A;  4KLN A;  1CR5 A;  3CF2 A;  2NVY A;  2C45 A;  1PYU B;  1SFO A;  2V45 A;  3O5A A;  2VUM A;  3QWZ A;  4CRZ A;  5FTK A;  1ZC1 A;  1OGY A;  1CZ4 A;  1PPY A;  2EEO B;  2Y0S A;  5C1B A;  3GTK A;  1E5V A;  2YUJ A;  3HU3 A;  3H0G A;  1UHE A;  4DMR A;  1DMS A;  3PLX B;  1PT0 A;  2PIC A;  2V3V A;  5FTM A;  1KQG A;  3GTQ A;  5T5M D;  3HKZ A;  2JIO A;  2WB1 A;  1KQF A;  1G8J A;  1YNJ D;  1Y1W A;  2PI8 A;  1E32 A;  4AOK B;  1CZ5 A;  1WLF A;  5GLF A;  1AW8 B;  1PYQ A;  3QQ8 A;  2JA5 A;  2WAQ A;  4D7Z B;  2KI8 A;  1Y5I A;  3TM7 B;  4AAY A;  5FTN A;  1QCS A;  2O5J D;  2R93 A;  2R92 A;  1PQF A;  1I3Q A;  1PT1 A;  4CS0 A;  1AA6 A;  4C2M A;  5FTL A;  1I50 A;  4QIW A;  1S3S A;  4KO8 A;  3DMR A;  2IV2 X;  2JIM A;  3GTL A;  1FDI A;  2NYA A;  3QQ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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