2C45A

Native precursor of pyruvoyl dependent aspartate decarboxylase
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
113
structure length
113
Chain Sequence
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of uncleaved L-aspartate-alpha-decarboxylase from Mycobacterium tuberculosis.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Lyase
molecule keywords Aspartate 1-decarboxylase
total genus 27
structure length 113
sequence length 113
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2005-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2c45A00
2Y0SA 4GA6A 1UHDA 1TMOA 3H0GA 1Y1VA 1K83A 3DMRA 3GTPA 5T5ID 2R93A 3GTQA 2IV2X 3QQ8A 2V45A 3IR6A 1AW8B 1H5NA 1R7RA 2KI8A 4CRZA 1EU1A 2EEOB 2VPYA 1E61A 1PT0A 2JA7A 4KODA 1WLFA 2PMZA 4CS0A 2PJHB 1CZ4A 2E2HA 1G8KA 1UHEA 4RV0A 3IR7A 3GTKA 2JA5A 1DMSA 4CRYG 3QC8A 1WCMA 2R92A 2JA6A 2NVXA 4QIWA 2JIMA 1Y4ZA 4AONB 4AOKB 2B63A 1OGYA 4KLNA 3GTGA 3QWZA 3CQZA 1R27A 1Q16A 2E7ZA 5B6CA 1PYQA 2NVYA 1PPYA 1PQEA 1E5VA 4AAYA 2R7ZA 1TWHA 1G8JA 5FTJA 1PT1A 2NYAA 1Y1WA 5FTNA 1VC3B 3TM7B 1R9TA 4C2MA 1CZ5A 1H0HA 3O5AA 3TIWA 2C45A 1PYUB 3FKIA 3OUGA 4D7ZB 1I3QA 1FDOA 1E60A 5T5MD 2VPZA 3PLXB 2JIPA 3HU2A 4AZDA 2V3VA 2WAQA 1SIWA 4KDLA 3GTOA 1FDIA 3HU3A 1Y5IA 1PQFA 5EPPA 4AYBA 3CF2A 1TWAA 2E2IA 1QCSA 1AA6A 2VUMA 5FTKA 3GTJA 2WB1A 2YU9A 5GLFA 2JIQA 1KQGA 3HU1A 4KO8A 3IR5A 1DMRA 1PQHA 4KDIA 3ML1A 4GA5A 5FTLA 2VPXA 1S3SA 1I50A 1E32A 1QDNA 3HKZA 1E18A 1SFOA 1TWFA 1IW7D 3QQ7A 2JIRA 1YLEA 2NAPA 2VPWA 2JIOA 5C1BA 3GTLA 5DYGA 5DYIA 1TWCA 5C18A 3GTMA 1TWGA 2DMRA 1CR5A 1KQFA 5FTMA 4DMRA
chains in the Genus database with same CATH superfamily
2Y0SA 2GAEA 4GA6A 1BW3A 1UHDA 1TMOA 3H0GA 1Y1VA 1K83A 3DMRA 3SUJA 3ENGA 1HD5A 5T5ID 3GTPA 2R93A 3GTQA 2IV2X 3QQ8A 3SULA 2V45A 1AW8B 1H5NA 3IR6A 1R7RA 2KI8A 5H4UA 3X2NA 4CRZA 3X2PA 4FFTA 1EU1A 4AVRA 2EEOB 1ZYRD 2VPYA 1E61A 2KQAA 2YUJA 1PT0A 2JA7A 4KODA 1WLFA 2PMZA 4CS0A 1CZ4A 1WC2A 2PJHB 3X2LA 4FG4A 1G8KA 1UHEA 4RV0A 2E2HA 1ZC1A 3IR7A 3GTKA 2JA5A 1DMSA 4CRYG 3QC8A 1WCMA 3D30A 4JP7A 4FG2A 2R92A 1L8FA 2NVXA 2JA6A 4QIWA 2JIMA 1YNND 2AE0X 2A69D 5GM9A 2A68D 1Y4ZA 4AONB 4AOKB 2B63A 1OGYA 4JS7A 4KLNA 3GTGA 3QWZA 5GLXA 3CQZA 1R27A 1Q16A 2E7ZA 5B6CA 1PYQA 2NVYA 1PPYA 4FERA 1PQEA 1SMYD 4JJOA 1E5VA 4AAYA 2R7ZA 1TWHA 1G8JA 2PNWA 5FTJA 1PT1A 2BH0A 2NYAA 2A6ED 1Y1WA 5FTNA 1VC3B 3TM7B 1R9TA 4C2MA 2ENGA 4NOHA 1CZ5A 1H0HA 3O5AA 3TIWA 2C45A 1PYUB 2G6GA 3FKIA 4JP6A 3OUGA 4D7ZB 1I3QA 1FDOA 1E60A 5T5MD 2O5JD 2VPZA 3PLXB 3X2GA 3X2OA 2JIPA 2A6HD 3HU2A 4AZDA 2V3VA 2WAQA 1SIWA 4KDLA 3X2MA 3GTOA 1FDIA 3X2JA 3X2IA 5GLYA 3HU3A 1Y5IA 1PQFA 5EPPA 3X2KA 4AYBA 1YNJD 3CF2A 1TWAA 3M3GA 2E2IA 1QCSA 1AA6A 2VUMA 4ENGA 5FTKA 3GTJA 2WB1A 2YU9A 5GLFA 2PJJA 2JIQA 2HCZX 1KQGA 3HU1A 1OA7A 3IR5A 2BE5D 1DMRA 4JCWA 1PQHA 4KO8A 5FTMA 1BW4A 4KDIA 3ML1A 3SUKA 4GA5A 4ZM7A 2G5DA 5FTLA 1N10A 2VPXA 4L48A 1S3SA 3SUMA 1I50A 3X2HA 1E32A 2CW0D 1QDNA 3HKZA 1E18A 1SFOA 1TWFA 1IW7D 3QQ7A 2JIRA 3CZBA 1YLEA 2NAPA 2VPWA 2JIOA 5C1BA 3GTLA 5DYGA 5DYIA 1TWCA 5C18A 3GTMA 1TWGA 2DMRA 1CR5A 1KQFA 1OA9A 2PI8A 2PICA 4DMRA
chains in the Genus database with same CATH topology
2Y0SA 2GAEA 4GA6A 1UHDA 1TMOA 3H0GA 1Y1VA 1K83A 3DMRA 3GTPA 5T5ID 2R93A 3GTQA 2IV2X 3QQ8A 2V45A 1AW8B 1H5NA 3IR6A 1R7RA 2KI8A 4CRZA 1EU1A 2EEOB 1ZYRD 2VPYA 1E61A 2YUJA 1PT0A 2JA7A 4KODA 1WLFA 2PMZA 4CS0A 2PJHB 1CZ4A 2E2HA 1G8KA 1UHEA 4RV0A 1ZC1A 3IR7A 3GTKA 2JA5A 1DMSA 4CRYG 3QC8A 1WCMA 2R92A 2JA6A 2NVXA 4QIWA 2JIMA 1YNND 2AE0X 2A69D 2A68D 1Y4ZA 4AONB 4AOKB 2B63A 1OGYA 4KLNA 3GTGA 3QWZA 3CQZA 1R27A 1Q16A 2E7ZA 5B6CA 1PYQA 2NVYA 1PPYA 1PQEA 1SMYD 1E5VA 4AAYA 2R7ZA 2PNWA 1G8JA 1TWHA 5FTJA 1PT1A 2NYAA 2A6ED 1Y1WA 5FTNA 1VC3B 3TM7B 1R9TA 4C2MA 4NOHA 1CZ5A 1H0HA 3O5AA 3TIWA 2C45A 1PYUB 2G6GA 3FKIA 3OUGA 4D7ZB 1I3QA 1FDOA 1E60A 5T5MD 2O5JD 2VPZA 3PLXB 2JIPA 2A6HD 3HU2A 4AZDA 2V3VA 2WAQA 1SIWA 4KDLA 3GTOA 1FDIA 3HU3A 1Y5IA 1PQFA 5EPPA 4AYBA 1YNJD 3CF2A 1TWAA 2E2IA 1QCSA 1AA6A 2VUMA 5FTKA 3GTJA 2WB1A 2YU9A 5GLFA 2PJJA 2JIQA 1KQGA 3HU1A 4KO8A 3IR5A 2BE5D 1DMRA 1PQHA 5FTMA 4KDIA 3ML1A 4GA5A 2G5DA 5FTLA 2VPXA 1S3SA 1I50A 1E32A 2CW0D 1QDNA 3HKZA 1E18A 1SFOA 1TWFA 1IW7D 3QQ7A 2JIRA 3CZBA 1YLEA 2NAPA 2VPWA 2JIOA 5C1BA 3GTLA 5DYGA 5DYIA 1TWCA 5C18A 3GTMA 1TWGA 2DMRA 1CR5A 1KQFA 2PI8A 2PICA 4DMRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y0S A;  4GA6 A;  1UHD A;  1TMO A;  3H0G A;  1Y1V A;  1K83 A;  3DMR A;  3GTP A;  5T5I D;  2R93 A;  3GTQ A;  2IV2 X;  3QQ8 A;  2V45 A;  3IR6 A;  1AW8 B;  1H5N A;  1R7R A;  2KI8 A;  4CRZ A;  1EU1 A;  2EEO B;  2VPY A;  1E61 A;  1PT0 A;  2JA7 A;  4KOD A;  1WLF A;  2PMZ A;  4CS0 A;  2PJH B;  1CZ4 A;  2E2H A;  1G8K A;  1UHE A;  4RV0 A;  3IR7 A;  3GTK A;  2JA5 A;  1DMS A;  4CRY G;  3QC8 A;  1WCM A;  2R92 A;  2JA6 A;  2NVX A;  4QIW A;  2JIM A;  1Y4Z A;  4AON B;  4AOK B;  2B63 A;  1OGY A;  4KLN A;  3GTG A;  3QWZ A;  3CQZ A;  1R27 A;  1Q16 A;  2E7Z A;  5B6C A;  1PYQ A;  2NVY A;  1PPY A;  1PQE A;  1E5V A;  4AAY A;  2R7Z A;  1TWH A;  1G8J A;  5FTJ A;  1PT1 A;  2NYA A;  1Y1W A;  5FTN A;  1VC3 B;  3TM7 B;  1R9T A;  4C2M A;  1CZ5 A;  1H0H A;  3O5A A;  3TIW A;  2C45 A;  1PYU B;  3FKI A;  3OUG A;  4D7Z B;  1I3Q A;  1FDO A;  1E60 A;  5T5M D;  2VPZ A;  3PLX B;  2JIP A;  3HU2 A;  4AZD A;  2V3V A;  2WAQ A;  1SIW A;  4KDL A;  3GTO A;  1FDI A;  3HU3 A;  1Y5I A;  1PQF A;  5EPP A;  4AYB A;  3CF2 A;  1TWA A;  2E2I A;  1QCS A;  1AA6 A;  2VUM A;  5FTK A;  3GTJ A;  2WB1 A;  2YU9 A;  5GLF A;  2JIQ A;  1KQG A;  3HU1 A;  4KO8 A;  3IR5 A;  1DMR A;  1PQH A;  4KDI A;  3ML1 A;  4GA5 A;  5FTL A;  2VPX A;  1S3S A;  1I50 A;  1E32 A;  1QDN A;  3HKZ A;  1E18 A;  1SFO A;  1TWF A;  1IW7 D;  3QQ7 A;  2JIR A;  1YLE A;  2NAP A;  2VPW A;  2JIO A;  5C1B A;  3GTL A;  5DYG A;  5DYI A;  1TWC A;  5C18 A;  3GTM A;  1TWG A;  2DMR A;  1CR5 A;  1KQF A;  5FTM A;  4DMR A; 
#chains in the Genus database with same CATH topology
 2Y0S A;  2GAE A;  4GA6 A;  1BW3 A;  1UHD A;  1TMO A;  3H0G A;  1Y1V A;  1K83 A;  3DMR A;  3SUJ A;  3ENG A;  1HD5 A;  5T5I D;  3GTP A;  2R93 A;  3GTQ A;  2IV2 X;  3QQ8 A;  3SUL A;  2V45 A;  1AW8 B;  1H5N A;  3IR6 A;  1R7R A;  2KI8 A;  5H4U A;  3X2N A;  4CRZ A;  3X2P A;  4FFT A;  1EU1 A;  4AVR A;  2EEO B;  1ZYR D;  2VPY A;  1E61 A;  2KQA A;  2YUJ A;  1PT0 A;  2JA7 A;  4KOD A;  1WLF A;  2PMZ A;  4CS0 A;  1CZ4 A;  1WC2 A;  2PJH B;  3X2L A;  4FG4 A;  1G8K A;  1UHE A;  4RV0 A;  2E2H A;  1ZC1 A;  3IR7 A;  3GTK A;  2JA5 A;  1DMS A;  4CRY G;  3QC8 A;  1WCM A;  3D30 A;  4JP7 A;  4FG2 A;  2R92 A;  1L8F A;  2NVX A;  2JA6 A;  4QIW A;  2JIM A;  1YNN D;  2AE0 X;  2A69 D;  5GM9 A;  2A68 D;  1Y4Z A;  4AON B;  4AOK B;  2B63 A;  1OGY A;  4JS7 A;  4KLN A;  3GTG A;  3QWZ A;  5GLX A;  3CQZ A;  1R27 A;  1Q16 A;  2E7Z A;  5B6C A;  1PYQ A;  2NVY A;  1PPY A;  4FER A;  1PQE A;  1SMY D;  4JJO A;  1E5V A;  4AAY A;  2R7Z A;  1TWH A;  1G8J A;  2PNW A;  5FTJ A;  1PT1 A;  2BH0 A;  2NYA A;  2A6E D;  1Y1W A;  5FTN A;  1VC3 B;  3TM7 B;  1R9T A;  4C2M A;  2ENG A;  4NOH A;  1CZ5 A;  1H0H A;  3O5A A;  3TIW A;  2C45 A;  1PYU B;  2G6G A;  3FKI A;  4JP6 A;  3OUG A;  4D7Z B;  1I3Q A;  1FDO A;  1E60 A;  5T5M D;  2O5J D;  2VPZ A;  3PLX B;  3X2G A;  3X2O A;  2JIP A;  2A6H D;  3HU2 A;  4AZD A;  2V3V A;  2WAQ A;  1SIW A;  4KDL A;  3X2M A;  3GTO A;  1FDI A;  3X2J A;  3X2I A;  5GLY A;  3HU3 A;  1Y5I A;  1PQF A;  5EPP A;  3X2K A;  4AYB A;  1YNJ D;  3CF2 A;  1TWA A;  3M3G A;  2E2I A;  1QCS A;  1AA6 A;  2VUM A;  4ENG A;  5FTK A;  3GTJ A;  2WB1 A;  2YU9 A;  5GLF A;  2PJJ A;  2JIQ A;  2HCZ X;  1KQG A;  3HU1 A;  1OA7 A;  3IR5 A;  2BE5 D;  1DMR A;  4JCW A;  1PQH A;  4KO8 A;  5FTM A;  1BW4 A;  4KDI A;  3ML1 A;  3SUK A;  4GA5 A;  4ZM7 A;  2G5D A;  5FTL A;  1N10 A;  2VPX A;  4L48 A;  1S3S A;  3SUM A;  1I50 A;  3X2H A;  1E32 A;  2CW0 D;  1QDN A;  3HKZ A;  1E18 A;  1SFO A;  1TWF A;  1IW7 D;  3QQ7 A;  2JIR A;  3CZB A;  1YLE A;  2NAP A;  2VPW A;  2JIO A;  5C1B A;  3GTL A;  5DYG A;  5DYI A;  1TWC A;  5C18 A;  3GTM A;  1TWG A;  2DMR A;  1CR5 A;  1KQF A;  1OA9 A;  2PI8 A;  2PIC A;  4DMR A; 
#chains in the Genus database with same CATH homology
 2Y0S A;  2GAE A;  4GA6 A;  1UHD A;  1TMO A;  3H0G A;  1Y1V A;  1K83 A;  3DMR A;  3GTP A;  5T5I D;  2R93 A;  3GTQ A;  2IV2 X;  3QQ8 A;  2V45 A;  1AW8 B;  1H5N A;  3IR6 A;  1R7R A;  2KI8 A;  4CRZ A;  1EU1 A;  2EEO B;  1ZYR D;  2VPY A;  1E61 A;  2YUJ A;  1PT0 A;  2JA7 A;  4KOD A;  1WLF A;  2PMZ A;  4CS0 A;  2PJH B;  1CZ4 A;  2E2H A;  1G8K A;  1UHE A;  4RV0 A;  1ZC1 A;  3IR7 A;  3GTK A;  2JA5 A;  1DMS A;  4CRY G;  3QC8 A;  1WCM A;  2R92 A;  2JA6 A;  2NVX A;  4QIW A;  2JIM A;  1YNN D;  2AE0 X;  2A69 D;  2A68 D;  1Y4Z A;  4AON B;  4AOK B;  2B63 A;  1OGY A;  4KLN A;  3GTG A;  3QWZ A;  3CQZ A;  1R27 A;  1Q16 A;  2E7Z A;  5B6C A;  1PYQ A;  2NVY A;  1PPY A;  1PQE A;  1SMY D;  1E5V A;  4AAY A;  2R7Z A;  2PNW A;  1G8J A;  1TWH A;  5FTJ A;  1PT1 A;  2NYA A;  2A6E D;  1Y1W A;  5FTN A;  1VC3 B;  3TM7 B;  1R9T A;  4C2M A;  4NOH A;  1CZ5 A;  1H0H A;  3O5A A;  3TIW A;  2C45 A;  1PYU B;  2G6G A;  3FKI A;  3OUG A;  4D7Z B;  1I3Q A;  1FDO A;  1E60 A;  5T5M D;  2O5J D;  2VPZ A;  3PLX B;  2JIP A;  2A6H D;  3HU2 A;  4AZD A;  2V3V A;  2WAQ A;  1SIW A;  4KDL A;  3GTO A;  1FDI A;  3HU3 A;  1Y5I A;  1PQF A;  5EPP A;  4AYB A;  1YNJ D;  3CF2 A;  1TWA A;  2E2I A;  1QCS A;  1AA6 A;  2VUM A;  5FTK A;  3GTJ A;  2WB1 A;  2YU9 A;  5GLF A;  2PJJ A;  2JIQ A;  1KQG A;  3HU1 A;  4KO8 A;  3IR5 A;  2BE5 D;  1DMR A;  1PQH A;  5FTM A;  4KDI A;  3ML1 A;  4GA5 A;  2G5D A;  5FTL A;  2VPX A;  1S3S A;  1I50 A;  1E32 A;  2CW0 D;  1QDN A;  3HKZ A;  1E18 A;  1SFO A;  1TWF A;  1IW7 D;  3QQ7 A;  2JIR A;  3CZB A;  1YLE A;  2NAP A;  2VPW A;  2JIO A;  5C1B A;  3GTL A;  5DYG A;  5DYI A;  1TWC A;  5C18 A;  3GTM A;  1TWG A;  2DMR A;  1CR5 A;  1KQF A;  2PI8 A;  2PIC A;  4DMR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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