2C45A

Native precursor of pyruvoyl dependent aspartate decarboxylase
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
113
structure length
113
Chain Sequence
b'MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNK'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Aspartate 1-decarboxylase
publication title Crystal structure of uncleaved L-aspartate-alpha-decarboxylase from Mycobacterium tuberculosis.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Lyase
total genus 27
structure length 113
sequence length 113
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2005-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2c45A00
2C45A 2EEOB 1E32A 4AONB 5C18A 4KDLA 2JIMA 2IV2X 1I3QA 1CZ5A 2E7ZA 5B6CA 1WLFA 3CF2A 4D7ZB 3HU1A 5EPPA 5DYGA 2R92A 5FTNA 1TWHA 1E60A 5T5ID 1OGYA 4AAYA 1TWCA 3CQZA 1DMRA 1S3SA 3H0GA 1QCSA 1QDNA 3GTPA 1PYQA 5FTLA 2V3VA 3QC8A 2VPZA 3GTGA 1PQFA 1PT1A 1TMOA 2VPWA 4GA5A 3QQ8A 5C1BA 4DMRA 5FTKA 1AW8B 2JIPA 1SFOA 3GTMA 2VPXA 4RV0A 1E61A 2NYAA 2NVXA 3HU2A 2PJHB 1WCMA 2NAPA 3DMRA 4CRYG 2JA5A 3GTKA 2PMZA 1TWFA 4AOKB 2V45A 2NVYA 3QWZA 1TWGA 2KI8A 1KQFA 1R27A 4KDIA 4C2MA 1E5VA 1AA6A 2YU9A 1G8KA 1PQEA 1KQGA 1YLEA 1FDOA 1K83A 2VUMA 3GTOA 3GTJA 2B63A 3TM7B 5DYIA 1UHDA 1I50A 1R9TA 1E18A 1PYUB 1PT0A 4CS0A 2JIRA 5FTMA 4AZDA 1Y4ZA 4KO8A 1Y1WA 2JIQA 3O5AA 1H0HA 3HU3A 5FTJA 2JA6A 5T5MD 1CR5A 4KODA 1IW7D 3PLXB 1VC3B 4KLNA 1G8JA 3HKZA 1UHEA 1PPYA 3GTLA 1R7RA 4AYBA 3ML1A 1EU1A 2R93A 1CZ4A 1SIWA 2R7ZA 3IR5A 3IR6A 1H5NA 2JA7A 1TWAA 1Y1VA 3QQ7A 2E2IA 1DMSA 2VPYA 2WB1A 2DMRA 3OUGA 5GLFA 2WAQA 4CRZA 3TIWA 1PQHA 3FKIA 1Q16A 2JIOA 2E2HA 4QIWA 2Y0SA 3GTQA 1FDIA 1Y5IA 3IR7A 4GA6A
chains in the Genus database with same CATH superfamily
2C45A 2EEOB 1E32A 4AONB 5C18A 4KDLA 2GAEA 2PI8A 2JIMA 2IV2X 2ENGA 1I3QA 1CZ5A 2E7ZA 5B6CA 3X2MA 1OA7A 1WLFA 3CF2A 4D7ZB 3HU1A 5EPPA 5DYGA 2R92A 5FTNA 1TWHA 1E60A 5T5ID 1OGYA 4AAYA 1TWCA 3CQZA 1DMRA 1S3SA 3H0GA 1QCSA 1QDNA 3GTPA 1PYQA 2AE0X 2PICA 1BW4A 2A6ED 5FTLA 2V3VA 3QC8A 4ZM7A 4FG4A 2VPZA 3X2PA 2A6HD 3GTGA 1PQFA 1PT1A 1TMOA 2VPWA 4GA5A 3QQ8A 4AVRA 5C1BA 3SUKA 4DMRA 2A68D 5FTKA 2PJJA 2G5DA 1AW8B 3X2KA 2JIPA 3X2LA 1SFOA 3GTMA 2VPXA 1YNND 4RV0A 1E61A 2NYAA 2NVXA 3CZBA 1HD5A 2PJHB 3HU2A 1WCMA 2NAPA 3DMRA 4CRYG 2JA5A 1N10A 3D30A 2PMZA 3GTKA 1TWFA 4AOKB 2V45A 2NVYA 4JCWA 3QWZA 1TWGA 2KI8A 1KQFA 1BW3A 1R27A 4KDIA 4NOHA 4C2MA 3SUMA 4JJOA 1E5VA 1AA6A 2YU9A 1G8KA 3X2NA 1PQEA 1KQGA 4ENGA 3SUJA 1YLEA 1FDOA 1K83A 2O5JD 4FG2A 2CW0D 2VUMA 3GTOA 3GTJA 2B63A 3X2OA 4FFTA 3TM7B 5DYIA 1UHDA 1ZYRD 1I50A 3ENGA 1R9TA 1E18A 1PYUB 3SULA 1PT0A 4CS0A 2JIRA 5FTMA 4AZDA 1Y4ZA 4KO8A 1Y1WA 2HCZX 2JIQA 1WC2A 3O5AA 1H0HA 3HU3A 5FTJA 2JA6A 2BH0A 5GM9A 5T5MD 2YUJA 1CR5A 4KODA 1IW7D 3PLXB 1VC3B 4KLNA 1G8JA 3X2JA 1SMYD 3HKZA 1UHEA 1PPYA 3GTLA 1R7RA 4AYBA 3X2HA 3ML1A 1EU1A 2R93A 1CZ4A 4L48A 1SIWA 2R7ZA 3IR5A 3X2GA 3IR6A 1OA9A 1H5NA 2JA7A 1TWAA 1Y1VA 3QQ7A 2A69D 1YNJD 2E2IA 2BE5D 4JS7A 1DMSA 2VPYA 2WB1A 5GLXA 5H4UA 2DMRA 3OUGA 5GLFA 1L8FA 5GLYA 2WAQA 4CRZA 2G6GA 3TIWA 1ZC1A 1PQHA 2PNWA 3FKIA 1Q16A 3X2IA 4JP6A 2JIOA 4JP7A 2E2HA 2KQAA 4QIWA 3M3GA 2Y0SA 4FERA 3GTQA 1FDIA 1Y5IA 3IR7A 4GA6A
chains in the Genus database with same CATH topology
2C45A 2EEOB 1E32A 4AONB 5C18A 4KDLA 2GAEA 2PI8A 2JIMA 2IV2X 1I3QA 1CZ5A 2E7ZA 5B6CA 1WLFA 3CF2A 4D7ZB 3HU1A 5EPPA 5DYGA 2R92A 5FTNA 1TWHA 1E60A 5T5ID 1OGYA 4AAYA 1TWCA 3CQZA 1DMRA 1S3SA 3H0GA 1QCSA 1QDNA 3GTPA 1PYQA 2AE0X 2PICA 2A6ED 5FTLA 2V3VA 3QC8A 2VPZA 2A6HD 3GTGA 1PQFA 1PT1A 1TMOA 2VPWA 4GA5A 3QQ8A 5C1BA 4DMRA 2A68D 5FTKA 2PJJA 2G5DA 1AW8B 2JIPA 1SFOA 3GTMA 2VPXA 1YNND 4RV0A 1E61A 2NYAA 2NVXA 3CZBA 3HU2A 2PJHB 1WCMA 2NAPA 3DMRA 4CRYG 2JA5A 3GTKA 2PMZA 1TWFA 4AOKB 2V45A 2NVYA 3QWZA 1TWGA 2KI8A 1KQFA 1R27A 4KDIA 4NOHA 4C2MA 1E5VA 1AA6A 2YU9A 1G8KA 1PQEA 1KQGA 1YLEA 1FDOA 1K83A 2O5JD 2VUMA 2CW0D 3GTOA 3GTJA 2B63A 3TM7B 5DYIA 1UHDA 1ZYRD 1I50A 1R9TA 1E18A 1PYUB 1PT0A 4CS0A 2JIRA 5FTMA 4AZDA 1Y4ZA 4KO8A 1Y1WA 2JIQA 3O5AA 1H0HA 3HU3A 5FTJA 2JA6A 5T5MD 2YUJA 1CR5A 4KODA 1IW7D 3PLXB 1VC3B 4KLNA 1G8JA 1SMYD 3HKZA 1UHEA 1PPYA 3GTLA 1R7RA 4AYBA 3ML1A 1EU1A 2R93A 1CZ4A 1SIWA 2R7ZA 3IR5A 3IR6A 1H5NA 2JA7A 1TWAA 1Y1VA 3QQ7A 2A69D 1YNJD 2E2IA 2BE5D 1DMSA 2VPYA 2WB1A 2DMRA 3OUGA 5GLFA 2WAQA 4CRZA 2G6GA 3TIWA 1ZC1A 1PQHA 2PNWA 3FKIA 1Q16A 2JIOA 2E2HA 4QIWA 2Y0SA 3GTQA 1FDIA 1Y5IA 3IR7A 4GA6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C45 A;  2EEO B;  1E32 A;  4AON B;  5C18 A;  4KDL A;  2JIM A;  2IV2 X;  1I3Q A;  1CZ5 A;  2E7Z A;  5B6C A;  1WLF A;  3CF2 A;  4D7Z B;  3HU1 A;  5EPP A;  5DYG A;  2R92 A;  5FTN A;  1TWH A;  1E60 A;  5T5I D;  1OGY A;  4AAY A;  1TWC A;  3CQZ A;  1DMR A;  1S3S A;  3H0G A;  1QCS A;  1QDN A;  3GTP A;  1PYQ A;  5FTL A;  2V3V A;  3QC8 A;  2VPZ A;  3GTG A;  1PQF A;  1PT1 A;  1TMO A;  2VPW A;  4GA5 A;  3QQ8 A;  5C1B A;  4DMR A;  5FTK A;  1AW8 B;  2JIP A;  1SFO A;  3GTM A;  2VPX A;  4RV0 A;  1E61 A;  2NYA A;  2NVX A;  3HU2 A;  2PJH B;  1WCM A;  2NAP A;  3DMR A;  4CRY G;  2JA5 A;  3GTK A;  2PMZ A;  1TWF A;  4AOK B;  2V45 A;  2NVY A;  3QWZ A;  1TWG A;  2KI8 A;  1KQF A;  1R27 A;  4KDI A;  4C2M A;  1E5V A;  1AA6 A;  2YU9 A;  1G8K A;  1PQE A;  1KQG A;  1YLE A;  1FDO A;  1K83 A;  2VUM A;  3GTO A;  3GTJ A;  2B63 A;  3TM7 B;  5DYI A;  1UHD A;  1I50 A;  1R9T A;  1E18 A;  1PYU B;  1PT0 A;  4CS0 A;  2JIR A;  5FTM A;  4AZD A;  1Y4Z A;  4KO8 A;  1Y1W A;  2JIQ A;  3O5A A;  1H0H A;  3HU3 A;  5FTJ A;  2JA6 A;  5T5M D;  1CR5 A;  4KOD A;  1IW7 D;  3PLX B;  1VC3 B;  4KLN A;  1G8J A;  3HKZ A;  1UHE A;  1PPY A;  3GTL A;  1R7R A;  4AYB A;  3ML1 A;  1EU1 A;  2R93 A;  1CZ4 A;  1SIW A;  2R7Z A;  3IR5 A;  3IR6 A;  1H5N A;  2JA7 A;  1TWA A;  1Y1V A;  3QQ7 A;  2E2I A;  1DMS A;  2VPY A;  2WB1 A;  2DMR A;  3OUG A;  5GLF A;  2WAQ A;  4CRZ A;  3TIW A;  1PQH A;  3FKI A;  1Q16 A;  2JIO A;  2E2H A;  4QIW A;  2Y0S A;  3GTQ A;  1FDI A;  1Y5I A;  3IR7 A;  4GA6 A; 
#chains in the Genus database with same CATH topology
 2C45 A;  2EEO B;  1E32 A;  4AON B;  5C18 A;  4KDL A;  2GAE A;  2PI8 A;  2JIM A;  2IV2 X;  2ENG A;  1I3Q A;  1CZ5 A;  2E7Z A;  5B6C A;  3X2M A;  1OA7 A;  1WLF A;  3CF2 A;  4D7Z B;  3HU1 A;  5EPP A;  5DYG A;  2R92 A;  5FTN A;  1TWH A;  1E60 A;  5T5I D;  1OGY A;  4AAY A;  1TWC A;  3CQZ A;  1DMR A;  1S3S A;  3H0G A;  1QCS A;  1QDN A;  3GTP A;  1PYQ A;  2AE0 X;  2PIC A;  1BW4 A;  2A6E D;  5FTL A;  2V3V A;  3QC8 A;  4ZM7 A;  4FG4 A;  2VPZ A;  3X2P A;  2A6H D;  3GTG A;  1PQF A;  1PT1 A;  1TMO A;  2VPW A;  4GA5 A;  3QQ8 A;  4AVR A;  5C1B A;  3SUK A;  4DMR A;  2A68 D;  5FTK A;  2PJJ A;  2G5D A;  1AW8 B;  3X2K A;  2JIP A;  3X2L A;  1SFO A;  3GTM A;  2VPX A;  1YNN D;  4RV0 A;  1E61 A;  2NYA A;  2NVX A;  3CZB A;  1HD5 A;  2PJH B;  3HU2 A;  1WCM A;  2NAP A;  3DMR A;  4CRY G;  2JA5 A;  1N10 A;  3D30 A;  2PMZ A;  3GTK A;  1TWF A;  4AOK B;  2V45 A;  2NVY A;  4JCW A;  3QWZ A;  1TWG A;  2KI8 A;  1KQF A;  1BW3 A;  1R27 A;  4KDI A;  4NOH A;  4C2M A;  3SUM A;  4JJO A;  1E5V A;  1AA6 A;  2YU9 A;  1G8K A;  3X2N A;  1PQE A;  1KQG A;  4ENG A;  3SUJ A;  1YLE A;  1FDO A;  1K83 A;  2O5J D;  4FG2 A;  2CW0 D;  2VUM A;  3GTO A;  3GTJ A;  2B63 A;  3X2O A;  4FFT A;  3TM7 B;  5DYI A;  1UHD A;  1ZYR D;  1I50 A;  3ENG A;  1R9T A;  1E18 A;  1PYU B;  3SUL A;  1PT0 A;  4CS0 A;  2JIR A;  5FTM A;  4AZD A;  1Y4Z A;  4KO8 A;  1Y1W A;  2HCZ X;  2JIQ A;  1WC2 A;  3O5A A;  1H0H A;  3HU3 A;  5FTJ A;  2JA6 A;  2BH0 A;  5GM9 A;  5T5M D;  2YUJ A;  1CR5 A;  4KOD A;  1IW7 D;  3PLX B;  1VC3 B;  4KLN A;  1G8J A;  3X2J A;  1SMY D;  3HKZ A;  1UHE A;  1PPY A;  3GTL A;  1R7R A;  4AYB A;  3X2H A;  3ML1 A;  1EU1 A;  2R93 A;  1CZ4 A;  4L48 A;  1SIW A;  2R7Z A;  3IR5 A;  3X2G A;  3IR6 A;  1OA9 A;  1H5N A;  2JA7 A;  1TWA A;  1Y1V A;  3QQ7 A;  2A69 D;  1YNJ D;  2E2I A;  2BE5 D;  4JS7 A;  1DMS A;  2VPY A;  2WB1 A;  5GLX A;  5H4U A;  2DMR A;  3OUG A;  5GLF A;  1L8F A;  5GLY A;  2WAQ A;  4CRZ A;  2G6G A;  3TIW A;  1ZC1 A;  1PQH A;  2PNW A;  3FKI A;  1Q16 A;  3X2I A;  4JP6 A;  2JIO A;  4JP7 A;  2E2H A;  2KQA A;  4QIW A;  3M3G A;  2Y0S A;  4FER A;  3GTQ A;  1FDI A;  1Y5I A;  3IR7 A;  4GA6 A; 
#chains in the Genus database with same CATH homology
 2C45 A;  2EEO B;  1E32 A;  4AON B;  5C18 A;  4KDL A;  2GAE A;  2PI8 A;  2JIM A;  2IV2 X;  1I3Q A;  1CZ5 A;  2E7Z A;  5B6C A;  1WLF A;  3CF2 A;  4D7Z B;  3HU1 A;  5EPP A;  5DYG A;  2R92 A;  5FTN A;  1TWH A;  1E60 A;  5T5I D;  1OGY A;  4AAY A;  1TWC A;  3CQZ A;  1DMR A;  1S3S A;  3H0G A;  1QCS A;  1QDN A;  3GTP A;  1PYQ A;  2AE0 X;  2PIC A;  2A6E D;  5FTL A;  2V3V A;  3QC8 A;  2VPZ A;  2A6H D;  3GTG A;  1PQF A;  1PT1 A;  1TMO A;  2VPW A;  4GA5 A;  3QQ8 A;  5C1B A;  4DMR A;  2A68 D;  5FTK A;  2PJJ A;  2G5D A;  1AW8 B;  2JIP A;  1SFO A;  3GTM A;  2VPX A;  1YNN D;  4RV0 A;  1E61 A;  2NYA A;  2NVX A;  3CZB A;  3HU2 A;  2PJH B;  1WCM A;  2NAP A;  3DMR A;  4CRY G;  2JA5 A;  3GTK A;  2PMZ A;  1TWF A;  4AOK B;  2V45 A;  2NVY A;  3QWZ A;  1TWG A;  2KI8 A;  1KQF A;  1R27 A;  4KDI A;  4NOH A;  4C2M A;  1E5V A;  1AA6 A;  2YU9 A;  1G8K A;  1PQE A;  1KQG A;  1YLE A;  1FDO A;  1K83 A;  2O5J D;  2VUM A;  2CW0 D;  3GTO A;  3GTJ A;  2B63 A;  3TM7 B;  5DYI A;  1UHD A;  1ZYR D;  1I50 A;  1R9T A;  1E18 A;  1PYU B;  1PT0 A;  4CS0 A;  2JIR A;  5FTM A;  4AZD A;  1Y4Z A;  4KO8 A;  1Y1W A;  2JIQ A;  3O5A A;  1H0H A;  3HU3 A;  5FTJ A;  2JA6 A;  5T5M D;  2YUJ A;  1CR5 A;  4KOD A;  1IW7 D;  3PLX B;  1VC3 B;  4KLN A;  1G8J A;  1SMY D;  3HKZ A;  1UHE A;  1PPY A;  3GTL A;  1R7R A;  4AYB A;  3ML1 A;  1EU1 A;  2R93 A;  1CZ4 A;  1SIW A;  2R7Z A;  3IR5 A;  3IR6 A;  1H5N A;  2JA7 A;  1TWA A;  1Y1V A;  3QQ7 A;  2A69 D;  1YNJ D;  2E2I A;  2BE5 D;  1DMS A;  2VPY A;  2WB1 A;  2DMR A;  3OUG A;  5GLF A;  2WAQ A;  4CRZ A;  2G6G A;  3TIW A;  1ZC1 A;  1PQH A;  2PNW A;  3FKI A;  1Q16 A;  2JIO A;  2E2H A;  4QIW A;  2Y0S A;  3GTQ A;  1FDI A;  1Y5I A;  3IR7 A;  4GA6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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