2C45A

Native precursor of pyruvoyl dependent aspartate decarboxylase
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
113
structure length
113
Chain Sequence
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of uncleaved L-aspartate-alpha-decarboxylase from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule keywords Aspartate 1-decarboxylase
molecule tags Lyase
source organism Mycobacterium tuberculosis
total genus 27
structure length 113
sequence length 113
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2005-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2c45A00
5FTKA 1AW8B 3O5AA 3IR6A 5FTMA 5T5ID 3GTOA 5FTNA 4RV0A 1Y1WA 3FKIA 2E2IA 3PLXB 2VPYA 1E32A 1FDIA 2V45A 1PPYA 4CRYG 2JIRA 3QC8A 1SIWA 3CQZA 1I50A 4AOKB 1R9TA 3GTKA 1H0HA 1DMSA 4GA6A 1Y4ZA 1OGYA 2JA5A 1CZ4A 1TWGA 1QCSA 3H0GA 3QQ7A 1DMRA 1TWAA 4KDIA 1CZ5A 2PJHB 2KI8A 3OUGA 4QIWA 1UHEA 2R92A 3CF2A 1VC3B 2V3VA 2WB1A 1PQFA 1TWFA 1S3SA 1E60A 1E61A 1G8KA 1WLFA 1UHDA 1SFOA 1Q16A 1YLEA 1IW7D 4AZDA 1PYUB 3IR7A 1EU1A 2DMRA 2R93A 2JA7A 5FTJA 1E18A 2NVYA 3HU2A 1PT1A 5DYIA 1E5VA 3GTMA 1K83A 4KODA 4C2MA 2JA6A 1G8JA 4AYBA 3IR5A 3GTQA 2EEOB 1R7RA 2Y0SA 4AONB 5EPPA 1TWCA 3DMRA 2VUMA 5T5MD 1FDOA 2JIMA 3GTPA 5DYGA 2VPZA 2JIPA 1PQEA 3HU1A 1I3QA 2JIOA 2YU9A 4D7ZB 1KQGA 2WAQA 2R7ZA 1KQFA 1CR5A 1TMOA 2NVXA 4AAYA 1Y5IA 1WCMA 4KO8A 5C18A 1AA6A 5B6CA 3GTJA 1R27A 2IV2X 2E7ZA 2E2HA 1PYQA 1Y1VA 1TWHA 4GA5A 3TIWA 1PT0A 1PQHA 2VPWA 3QWZA 2JIQA 3TM7B 4CS0A 4DMRA 3GTLA 2C45A 5C1BA 2PMZA 3GTGA 2VPXA 4KDLA 3HKZA 5GLFA 3QQ8A 2NYAA 4CRZA 3HU3A 2B63A 1H5NA 3ML1A 1QDNA 5FTLA 2NAPA 4KLNA
chains in the Genus database with same CATH superfamily
2A68D 5FTKA 1AW8B 3O5AA 4NOHA 3IR6A 5FTMA 5T5ID 3GTOA 5FTNA 4JS7A 1ZYRD 3SUMA 3X2NA 4RV0A 1Y1WA 3SULA 3FKIA 2E2IA 3PLXB 2VPYA 1E32A 1FDIA 2V45A 1PPYA 2CW0D 4FG4A 1L8FA 4CRYG 2JIRA 3QC8A 1SIWA 3X2MA 2BH0A 3CQZA 3SUJA 1I50A 4AOKB 1R9TA 4FG2A 3GTKA 4ZM7A 1H0HA 1DMSA 4GA6A 1Y4ZA 1OGYA 2G6GA 1CZ4A 2JA5A 1TWGA 1WC2A 2A6ED 2A69D 1OA9A 1QCSA 3H0GA 3SUKA 5GLYA 3QQ7A 1DMRA 1TWAA 4KDIA 3X2PA 3X2JA 2PJHB 1CZ5A 2BE5D 5GLXA 1N10A 2KI8A 3OUGA 4QIWA 4JP7A 1UHEA 2ENGA 2R92A 3CF2A 1VC3B 4ENGA 5GM9A 2V3VA 2WB1A 1PQFA 4FFTA 2O5JD 1TWFA 1S3SA 1E60A 1E61A 1G8KA 1WLFA 1UHDA 2KQAA 1SFOA 1Q16A 1YLEA 1IW7D 4AZDA 1PYUB 3IR7A 1EU1A 2DMRA 2R93A 2JA7A 5FTJA 4JCWA 1E18A 2NVYA 3HU2A 1HD5A 2PICA 1PT1A 5DYIA 1E5VA 3GTMA 1K83A 3X2LA 4KODA 4C2MA 2JA6A 1G8JA 4AYBA 3IR5A 3GTQA 2EEOB 1R7RA 2GAEA 2Y0SA 4AONB 5EPPA 1TWCA 3DMRA 2VUMA 2G5DA 5T5MD 1FDOA 2JIMA 3GTPA 3X2GA 5DYGA 1BW4A 1YNND 2VPZA 2JIPA 1PQEA 2A6HD 3HU1A 2JIOA 1I3QA 2YU9A 3X2OA 4JP6A 4D7ZB 1KQGA 2WAQA 2R7ZA 1KQFA 1YNJD 1CR5A 1TMOA 2NVXA 4AAYA 1BW3A 1Y5IA 2AE0X 1WCMA 4KO8A 2HCZX 3CZBA 5C18A 1AA6A 5B6CA 3GTJA 4AVRA 1R27A 3X2IA 2IV2X 2E7ZA 2E2HA 1PYQA 1Y1VA 3ENGA 1TWHA 4GA5A 3TIWA 1PT0A 2PJJA 3M3GA 1PQHA 1SMYD 2VPWA 3QWZA 2JIQA 3TM7B 4CS0A 4DMRA 3GTLA 2C45A 4FERA 5C1BA 2PMZA 3GTGA 2PNWA 2VPXA 5H4UA 4KDLA 3HKZA 5GLFA 1OA7A 2PI8A 3X2HA 3QQ8A 2NYAA 3D30A 4L48A 4CRZA 3HU3A 2B63A 3X2KA 1H5NA 4JJOA 1ZC1A 3ML1A 1QDNA 2YUJA 5FTLA 2NAPA 4KLNA
chains in the Genus database with same CATH topology
2A68D 5FTKA 1AW8B 3O5AA 4NOHA 3IR6A 5FTMA 5T5ID 3GTOA 5FTNA 1ZYRD 4RV0A 1Y1WA 3FKIA 2E2IA 3PLXB 2VPYA 1E32A 1FDIA 2V45A 1PPYA 2CW0D 4CRYG 2JIRA 3QC8A 1SIWA 3CQZA 1I50A 4AOKB 1R9TA 3GTKA 1H0HA 1DMSA 4GA6A 1Y4ZA 1OGYA 2G6GA 1CZ4A 2JA5A 1TWGA 2A6ED 2A69D 1QCSA 3H0GA 3QQ7A 1DMRA 1TWAA 4KDIA 1CZ5A 2PJHB 2BE5D 2KI8A 3OUGA 4QIWA 1UHEA 2R92A 3CF2A 1VC3B 2V3VA 2WB1A 1PQFA 2O5JD 1TWFA 1S3SA 1E60A 1E61A 1G8KA 1WLFA 1UHDA 1SFOA 1Q16A 1YLEA 1IW7D 4AZDA 1PYUB 3IR7A 1EU1A 2DMRA 2R93A 2JA7A 5FTJA 1E18A 2NVYA 3HU2A 2PICA 1PT1A 5DYIA 1E5VA 3GTMA 1K83A 4KODA 4C2MA 2JA6A 1G8JA 4AYBA 3IR5A 3GTQA 2EEOB 1R7RA 2GAEA 2Y0SA 4AONB 5EPPA 1TWCA 3DMRA 2VUMA 2G5DA 5T5MD 1FDOA 2JIMA 3GTPA 5DYGA 1YNND 2VPZA 2JIPA 1PQEA 2A6HD 3HU1A 2JIOA 1I3QA 2YU9A 4D7ZB 1KQGA 2WAQA 2R7ZA 1KQFA 1YNJD 1CR5A 1TMOA 2NVXA 4AAYA 1Y5IA 2AE0X 1WCMA 4KO8A 5C18A 3CZBA 1AA6A 5B6CA 3GTJA 1R27A 2IV2X 2E7ZA 2E2HA 1PYQA 1Y1VA 1TWHA 4GA5A 3TIWA 1PT0A 2PJJA 1PQHA 1SMYD 2VPWA 3QWZA 2JIQA 3TM7B 4CS0A 4DMRA 3GTLA 2C45A 5C1BA 2PMZA 3GTGA 2PNWA 2VPXA 4KDLA 3HKZA 5GLFA 2PI8A 3QQ8A 2NYAA 4CRZA 3HU3A 2B63A 1H5NA 1ZC1A 3ML1A 1QDNA 2YUJA 5FTLA 2NAPA 4KLNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FTK A;  1AW8 B;  3O5A A;  3IR6 A;  5FTM A;  5T5I D;  3GTO A;  5FTN A;  4RV0 A;  1Y1W A;  3FKI A;  2E2I A;  3PLX B;  2VPY A;  1E32 A;  1FDI A;  2V45 A;  1PPY A;  4CRY G;  2JIR A;  3QC8 A;  1SIW A;  3CQZ A;  1I50 A;  4AOK B;  1R9T A;  3GTK A;  1H0H A;  1DMS A;  4GA6 A;  1Y4Z A;  1OGY A;  2JA5 A;  1CZ4 A;  1TWG A;  1QCS A;  3H0G A;  3QQ7 A;  1DMR A;  1TWA A;  4KDI A;  1CZ5 A;  2PJH B;  2KI8 A;  3OUG A;  4QIW A;  1UHE A;  2R92 A;  3CF2 A;  1VC3 B;  2V3V A;  2WB1 A;  1PQF A;  1TWF A;  1S3S A;  1E60 A;  1E61 A;  1G8K A;  1WLF A;  1UHD A;  1SFO A;  1Q16 A;  1YLE A;  1IW7 D;  4AZD A;  1PYU B;  3IR7 A;  1EU1 A;  2DMR A;  2R93 A;  2JA7 A;  5FTJ A;  1E18 A;  2NVY A;  3HU2 A;  1PT1 A;  5DYI A;  1E5V A;  3GTM A;  1K83 A;  4KOD A;  4C2M A;  2JA6 A;  1G8J A;  4AYB A;  3IR5 A;  3GTQ A;  2EEO B;  1R7R A;  2Y0S A;  4AON B;  5EPP A;  1TWC A;  3DMR A;  2VUM A;  5T5M D;  1FDO A;  2JIM A;  3GTP A;  5DYG A;  2VPZ A;  2JIP A;  1PQE A;  3HU1 A;  1I3Q A;  2JIO A;  2YU9 A;  4D7Z B;  1KQG A;  2WAQ A;  2R7Z A;  1KQF A;  1CR5 A;  1TMO A;  2NVX A;  4AAY A;  1Y5I A;  1WCM A;  4KO8 A;  5C18 A;  1AA6 A;  5B6C A;  3GTJ A;  1R27 A;  2IV2 X;  2E7Z A;  2E2H A;  1PYQ A;  1Y1V A;  1TWH A;  4GA5 A;  3TIW A;  1PT0 A;  1PQH A;  2VPW A;  3QWZ A;  2JIQ A;  3TM7 B;  4CS0 A;  4DMR A;  3GTL A;  2C45 A;  5C1B A;  2PMZ A;  3GTG A;  2VPX A;  4KDL A;  3HKZ A;  5GLF A;  3QQ8 A;  2NYA A;  4CRZ A;  3HU3 A;  2B63 A;  1H5N A;  3ML1 A;  1QDN A;  5FTL A;  2NAP A;  4KLN A; 
#chains in the Genus database with same CATH topology
 2A68 D;  5FTK A;  1AW8 B;  3O5A A;  4NOH A;  3IR6 A;  5FTM A;  5T5I D;  3GTO A;  5FTN A;  4JS7 A;  1ZYR D;  3SUM A;  3X2N A;  4RV0 A;  1Y1W A;  3SUL A;  3FKI A;  2E2I A;  3PLX B;  2VPY A;  1E32 A;  1FDI A;  2V45 A;  1PPY A;  2CW0 D;  4FG4 A;  1L8F A;  4CRY G;  2JIR A;  3QC8 A;  1SIW A;  3X2M A;  2BH0 A;  3CQZ A;  3SUJ A;  1I50 A;  4AOK B;  1R9T A;  4FG2 A;  3GTK A;  4ZM7 A;  1H0H A;  1DMS A;  4GA6 A;  1Y4Z A;  1OGY A;  2G6G A;  1CZ4 A;  2JA5 A;  1TWG A;  1WC2 A;  2A6E D;  2A69 D;  1OA9 A;  1QCS A;  3H0G A;  3SUK A;  5GLY A;  3QQ7 A;  1DMR A;  1TWA A;  4KDI A;  3X2P A;  3X2J A;  2PJH B;  1CZ5 A;  2BE5 D;  5GLX A;  1N10 A;  2KI8 A;  3OUG A;  4QIW A;  4JP7 A;  1UHE A;  2ENG A;  2R92 A;  3CF2 A;  1VC3 B;  4ENG A;  5GM9 A;  2V3V A;  2WB1 A;  1PQF A;  4FFT A;  2O5J D;  1TWF A;  1S3S A;  1E60 A;  1E61 A;  1G8K A;  1WLF A;  1UHD A;  2KQA A;  1SFO A;  1Q16 A;  1YLE A;  1IW7 D;  4AZD A;  1PYU B;  3IR7 A;  1EU1 A;  2DMR A;  2R93 A;  2JA7 A;  5FTJ A;  4JCW A;  1E18 A;  2NVY A;  3HU2 A;  1HD5 A;  2PIC A;  1PT1 A;  5DYI A;  1E5V A;  3GTM A;  1K83 A;  3X2L A;  4KOD A;  4C2M A;  2JA6 A;  1G8J A;  4AYB A;  3IR5 A;  3GTQ A;  2EEO B;  1R7R A;  2GAE A;  2Y0S A;  4AON B;  5EPP A;  1TWC A;  3DMR A;  2VUM A;  2G5D A;  5T5M D;  1FDO A;  2JIM A;  3GTP A;  3X2G A;  5DYG A;  1BW4 A;  1YNN D;  2VPZ A;  2JIP A;  1PQE A;  2A6H D;  3HU1 A;  2JIO A;  1I3Q A;  2YU9 A;  3X2O A;  4JP6 A;  4D7Z B;  1KQG A;  2WAQ A;  2R7Z A;  1KQF A;  1YNJ D;  1CR5 A;  1TMO A;  2NVX A;  4AAY A;  1BW3 A;  1Y5I A;  2AE0 X;  1WCM A;  4KO8 A;  2HCZ X;  3CZB A;  5C18 A;  1AA6 A;  5B6C A;  3GTJ A;  4AVR A;  1R27 A;  3X2I A;  2IV2 X;  2E7Z A;  2E2H A;  1PYQ A;  1Y1V A;  3ENG A;  1TWH A;  4GA5 A;  3TIW A;  1PT0 A;  2PJJ A;  3M3G A;  1PQH A;  1SMY D;  2VPW A;  3QWZ A;  2JIQ A;  3TM7 B;  4CS0 A;  4DMR A;  3GTL A;  2C45 A;  4FER A;  5C1B A;  2PMZ A;  3GTG A;  2PNW A;  2VPX A;  5H4U A;  4KDL A;  3HKZ A;  5GLF A;  1OA7 A;  2PI8 A;  3X2H A;  3QQ8 A;  2NYA A;  3D30 A;  4L48 A;  4CRZ A;  3HU3 A;  2B63 A;  3X2K A;  1H5N A;  4JJO A;  1ZC1 A;  3ML1 A;  1QDN A;  2YUJ A;  5FTL A;  2NAP A;  4KLN A; 
#chains in the Genus database with same CATH homology
 2A68 D;  5FTK A;  1AW8 B;  3O5A A;  4NOH A;  3IR6 A;  5FTM A;  5T5I D;  3GTO A;  5FTN A;  1ZYR D;  4RV0 A;  1Y1W A;  3FKI A;  2E2I A;  3PLX B;  2VPY A;  1E32 A;  1FDI A;  2V45 A;  1PPY A;  2CW0 D;  4CRY G;  2JIR A;  3QC8 A;  1SIW A;  3CQZ A;  1I50 A;  4AOK B;  1R9T A;  3GTK A;  1H0H A;  1DMS A;  4GA6 A;  1Y4Z A;  1OGY A;  2G6G A;  1CZ4 A;  2JA5 A;  1TWG A;  2A6E D;  2A69 D;  1QCS A;  3H0G A;  3QQ7 A;  1DMR A;  1TWA A;  4KDI A;  1CZ5 A;  2PJH B;  2BE5 D;  2KI8 A;  3OUG A;  4QIW A;  1UHE A;  2R92 A;  3CF2 A;  1VC3 B;  2V3V A;  2WB1 A;  1PQF A;  2O5J D;  1TWF A;  1S3S A;  1E60 A;  1E61 A;  1G8K A;  1WLF A;  1UHD A;  1SFO A;  1Q16 A;  1YLE A;  1IW7 D;  4AZD A;  1PYU B;  3IR7 A;  1EU1 A;  2DMR A;  2R93 A;  2JA7 A;  5FTJ A;  1E18 A;  2NVY A;  3HU2 A;  2PIC A;  1PT1 A;  5DYI A;  1E5V A;  3GTM A;  1K83 A;  4KOD A;  4C2M A;  2JA6 A;  1G8J A;  4AYB A;  3IR5 A;  3GTQ A;  2EEO B;  1R7R A;  2GAE A;  2Y0S A;  4AON B;  5EPP A;  1TWC A;  3DMR A;  2VUM A;  2G5D A;  5T5M D;  1FDO A;  2JIM A;  3GTP A;  5DYG A;  1YNN D;  2VPZ A;  2JIP A;  1PQE A;  2A6H D;  3HU1 A;  2JIO A;  1I3Q A;  2YU9 A;  4D7Z B;  1KQG A;  2WAQ A;  2R7Z A;  1KQF A;  1YNJ D;  1CR5 A;  1TMO A;  2NVX A;  4AAY A;  1Y5I A;  2AE0 X;  1WCM A;  4KO8 A;  5C18 A;  3CZB A;  1AA6 A;  5B6C A;  3GTJ A;  1R27 A;  2IV2 X;  2E7Z A;  2E2H A;  1PYQ A;  1Y1V A;  1TWH A;  4GA5 A;  3TIW A;  1PT0 A;  2PJJ A;  1PQH A;  1SMY D;  2VPW A;  3QWZ A;  2JIQ A;  3TM7 B;  4CS0 A;  4DMR A;  3GTL A;  2C45 A;  5C1B A;  2PMZ A;  3GTG A;  2PNW A;  2VPX A;  4KDL A;  3HKZ A;  5GLF A;  2PI8 A;  3QQ8 A;  2NYA A;  4CRZ A;  3HU3 A;  2B63 A;  1H5N A;  1ZC1 A;  3ML1 A;  1QDN A;  2YUJ A;  5FTL A;  2NAP A;  4KLN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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