2C45A

Native precursor of pyruvoyl dependent aspartate decarboxylase
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
113
structure length
113
Chain Sequence
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Aspartate 1-decarboxylase
publication title Crystal structure of uncleaved L-aspartate-alpha-decarboxylase from Mycobacterium tuberculosis.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Lyase
total genus 27
structure length 113
sequence length 113
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2005-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2c45A00
2PJHB 2JA6A 3IR7A 1PT1A 2V45A 1E32A 3QWZA 1OGYA 2E2IA 4GA6A 1H0HA 3OUGA 1Y1VA 2EEOB 1QCSA 4KODA 1AA6A 3QQ8A 2NYAA 4AONB 4C2MA 1DMSA 3QQ7A 3IR6A 4KDLA 2VPYA 1FDOA 5FTKA 3TM7B 3CF2A 4CRYG 4KLNA 5DYGA 5C18A 5B6CA 1EU1A 1CZ4A 3PLXB 2WB1A 3GTGA 1PQHA 2VPWA 2V3VA 1R7RA 3GTPA 2NAPA 1S3SA 1E5VA 1TWGA 2VUMA 1SIWA 5T5MD 1PYQA 5GLFA 1R27A 1CR5A 5C1BA 5FTJA 1TWFA 5FTMA 4QIWA 3QC8A 3GTLA 1E60A 4AYBA 1PQEA 2JIQA 2PMZA 4AAYA 5EPPA 1TWAA 1FDIA 3O5AA 1TMOA 4AZDA 2R93A 2WAQA 3HU2A 1KQGA 1E61A 2JA5A 1TWHA 1VC3B 4KDIA 2JIPA 1WLFA 4AOKB 1AW8B 3GTKA 5FTLA 1PQFA 3HU3A 2C45A 1R9TA 3IR5A 3HKZA 1I50A 3DMRA 1KQFA 2KI8A 5FTNA 3GTOA 2NVXA 1Y5IA 2Y0SA 1Y4ZA 1YLEA 1WCMA 1E18A 4CRZA 3TIWA 3GTMA 1DMRA 2E2HA 1Y1WA 4GA5A 2NVYA 2VPXA 2R7ZA 3H0GA 5DYIA 2R92A 2JIOA 2VPZA 2JIRA 4KO8A 1SFOA 4CS0A 2JA7A 1PPYA 1TWCA 1IW7D 5T5ID 3ML1A 1I3QA 1Q16A 3HU1A 1G8JA 2IV2X 1PT0A 2DMRA 2YU9A 1UHEA 2E7ZA 1K83A 2B63A 1CZ5A 1UHDA 4D7ZB 1QDNA 1PYUB 3FKIA 3GTQA 1G8KA 3GTJA 4DMRA 1H5NA 2JIMA 3CQZA 4RV0A
chains in the Genus database with same CATH superfamily
4JP6A 2PJHB 2JA6A 2PI8A 3CZBA 3X2NA 3D30A 1PT1A 3IR7A 2V45A 1E32A 3QWZA 1OGYA 4JJOA 4JS7A 4GA6A 1H0HA 3OUGA 2E2IA 1YNJD 1Y1VA 2EEOB 4JP7A 1QCSA 4KODA 1AA6A 3QQ8A 2NYAA 4AONB 4JCWA 4C2MA 1DMSA 2BH0A 3QQ7A 3IR6A 4KDLA 2VPYA 3X2LA 1FDOA 5FTKA 3TM7B 3CF2A 4CRYG 4KLNA 5DYGA 2A69D 4AVRA 5C18A 5B6CA 1EU1A 1CZ4A 1L8FA 1OA7A 2PNWA 2WB1A 2G5DA 3PLXB 3GTGA 1PQHA 2VPWA 2V3VA 1R7RA 4L48A 3GTPA 2NAPA 1S3SA 2AE0X 1E5VA 1TWGA 2PICA 1SIWA 2VUMA 3X2KA 3X2IA 5T5MD 1PYQA 5GLFA 1R27A 1CR5A 3X2PA 5C1BA 5FTJA 1TWFA 3SUMA 5FTMA 4QIWA 3QC8A 3GTLA 1E60A 3SUKA 4AYBA 5GLXA 1PQEA 2JIQA 2PMZA 1HD5A 4AAYA 2YUJA 1BW3A 2KQAA 3X2MA 4FG4A 1WC2A 2BE5D 5EPPA 1TWAA 5GLYA 1FDIA 3O5AA 4ENGA 1TMOA 2A68D 4AZDA 2R93A 2WAQA 3HU2A 3SUJA 1E61A 1KQGA 2JA5A 3X2JA 1TWHA 2O5JD 1VC3B 4KDIA 1BW4A 2JIPA 3X2HA 1WLFA 4FERA 4AOKB 1AW8B 3GTKA 5FTLA 1PQFA 3HU3A 2C45A 2A6ED 1R9TA 3IR5A 3HKZA 1I50A 3DMRA 1KQFA 2KI8A 5FTNA 3SULA 1OA9A 3GTOA 2NVXA 1Y5IA 2Y0SA 1Y4ZA 1YLEA 2HCZX 1WCMA 1E18A 4CRZA 4ZM7A 3TIWA 3GTMA 1DMRA 2E2HA 2GAEA 1Y1WA 1ZYRD 1SMYD 4GA5A 2NVYA 5H4UA 2VPXA 3X2OA 2PJJA 3M3GA 2R7ZA 3H0GA 5DYIA 2ENGA 4FFTA 4NOHA 2R92A 2JIOA 2VPZA 2JIRA 4KO8A 1SFOA 4CS0A 2JA7A 1PPYA 1TWCA 1IW7D 5T5ID 4FG2A 3ML1A 1I3QA 1Q16A 3HU1A 1G8JA 5GM9A 2IV2X 1PT0A 1ZC1A 2DMRA 2G6GA 2YU9A 1UHEA 2E7ZA 1K83A 2B63A 1CZ5A 1UHDA 4D7ZB 1QDNA 1PYUB 2CW0D 3FKIA 3GTQA 1G8KA 3GTJA 4DMRA 1H5NA 2JIMA 3ENGA 3CQZA 1YNND 1N10A 3X2GA 2A6HD 4RV0A
chains in the Genus database with same CATH topology
2PJHB 2JA6A 2PI8A 3CZBA 3IR7A 1PT1A 2V45A 1E32A 3QWZA 1OGYA 2E2IA 4GA6A 1H0HA 3OUGA 1YNJD 1Y1VA 2EEOB 1QCSA 4KODA 1AA6A 3QQ8A 2NYAA 4AONB 4C2MA 1DMSA 3QQ7A 3IR6A 4KDLA 2VPYA 1FDOA 5FTKA 3TM7B 3CF2A 4CRYG 4KLNA 5DYGA 2A69D 5C18A 5B6CA 1EU1A 1CZ4A 3PLXB 2PNWA 2WB1A 3GTGA 2G5DA 1PQHA 2VPWA 2V3VA 1R7RA 3GTPA 2NAPA 1S3SA 2AE0X 1E5VA 1TWGA 2PICA 1SIWA 2VUMA 5T5MD 1PYQA 5GLFA 1R27A 1CR5A 5C1BA 5FTJA 1TWFA 5FTMA 4QIWA 3QC8A 3GTLA 1E60A 4AYBA 1PQEA 2JIQA 2PMZA 4AAYA 2YUJA 2BE5D 5EPPA 1TWAA 1FDIA 3O5AA 1TMOA 2A68D 4AZDA 2R93A 2WAQA 3HU2A 1KQGA 1E61A 2JA5A 1TWHA 2O5JD 1VC3B 4KDIA 2JIPA 1WLFA 4AOKB 1AW8B 3GTKA 5FTLA 1PQFA 3HU3A 2C45A 2A6ED 1R9TA 3IR5A 3HKZA 1I50A 3DMRA 1KQFA 2KI8A 5FTNA 3GTOA 2NVXA 1Y5IA 2Y0SA 1Y4ZA 1YLEA 1WCMA 1E18A 4CRZA 3TIWA 3GTMA 1DMRA 2E2HA 2GAEA 1Y1WA 1ZYRD 1SMYD 4GA5A 2NVYA 2VPXA 2PJJA 2R7ZA 3H0GA 5DYIA 4NOHA 2R92A 2JIOA 2VPZA 2JIRA 4KO8A 1SFOA 4CS0A 2JA7A 1PPYA 1TWCA 1IW7D 5T5ID 3ML1A 1I3QA 1Q16A 3HU1A 1G8JA 2IV2X 1PT0A 1ZC1A 2DMRA 2G6GA 2YU9A 1UHEA 2E7ZA 1K83A 2B63A 1CZ5A 1UHDA 4D7ZB 1QDNA 1PYUB 2CW0D 3FKIA 3GTQA 1G8KA 3GTJA 4DMRA 1H5NA 2JIMA 3CQZA 1YNND 2A6HD 4RV0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PJH B;  2JA6 A;  3IR7 A;  1PT1 A;  2V45 A;  1E32 A;  3QWZ A;  1OGY A;  2E2I A;  4GA6 A;  1H0H A;  3OUG A;  1Y1V A;  2EEO B;  1QCS A;  4KOD A;  1AA6 A;  3QQ8 A;  2NYA A;  4AON B;  4C2M A;  1DMS A;  3QQ7 A;  3IR6 A;  4KDL A;  2VPY A;  1FDO A;  5FTK A;  3TM7 B;  3CF2 A;  4CRY G;  4KLN A;  5DYG A;  5C18 A;  5B6C A;  1EU1 A;  1CZ4 A;  3PLX B;  2WB1 A;  3GTG A;  1PQH A;  2VPW A;  2V3V A;  1R7R A;  3GTP A;  2NAP A;  1S3S A;  1E5V A;  1TWG A;  2VUM A;  1SIW A;  5T5M D;  1PYQ A;  5GLF A;  1R27 A;  1CR5 A;  5C1B A;  5FTJ A;  1TWF A;  5FTM A;  4QIW A;  3QC8 A;  3GTL A;  1E60 A;  4AYB A;  1PQE A;  2JIQ A;  2PMZ A;  4AAY A;  5EPP A;  1TWA A;  1FDI A;  3O5A A;  1TMO A;  4AZD A;  2R93 A;  2WAQ A;  3HU2 A;  1KQG A;  1E61 A;  2JA5 A;  1TWH A;  1VC3 B;  4KDI A;  2JIP A;  1WLF A;  4AOK B;  1AW8 B;  3GTK A;  5FTL A;  1PQF A;  3HU3 A;  2C45 A;  1R9T A;  3IR5 A;  3HKZ A;  1I50 A;  3DMR A;  1KQF A;  2KI8 A;  5FTN A;  3GTO A;  2NVX A;  1Y5I A;  2Y0S A;  1Y4Z A;  1YLE A;  1WCM A;  1E18 A;  4CRZ A;  3TIW A;  3GTM A;  1DMR A;  2E2H A;  1Y1W A;  4GA5 A;  2NVY A;  2VPX A;  2R7Z A;  3H0G A;  5DYI A;  2R92 A;  2JIO A;  2VPZ A;  2JIR A;  4KO8 A;  1SFO A;  4CS0 A;  2JA7 A;  1PPY A;  1TWC A;  1IW7 D;  5T5I D;  3ML1 A;  1I3Q A;  1Q16 A;  3HU1 A;  1G8J A;  2IV2 X;  1PT0 A;  2DMR A;  2YU9 A;  1UHE A;  2E7Z A;  1K83 A;  2B63 A;  1CZ5 A;  1UHD A;  4D7Z B;  1QDN A;  1PYU B;  3FKI A;  3GTQ A;  1G8K A;  3GTJ A;  4DMR A;  1H5N A;  2JIM A;  3CQZ A;  4RV0 A; 
#chains in the Genus database with same CATH topology
 4JP6 A;  2PJH B;  2JA6 A;  2PI8 A;  3CZB A;  3X2N A;  3D30 A;  1PT1 A;  3IR7 A;  2V45 A;  1E32 A;  3QWZ A;  1OGY A;  4JJO A;  4JS7 A;  4GA6 A;  1H0H A;  3OUG A;  2E2I A;  1YNJ D;  1Y1V A;  2EEO B;  4JP7 A;  1QCS A;  4KOD A;  1AA6 A;  3QQ8 A;  2NYA A;  4AON B;  4JCW A;  4C2M A;  1DMS A;  2BH0 A;  3QQ7 A;  3IR6 A;  4KDL A;  2VPY A;  3X2L A;  1FDO A;  5FTK A;  3TM7 B;  3CF2 A;  4CRY G;  4KLN A;  5DYG A;  2A69 D;  4AVR A;  5C18 A;  5B6C A;  1EU1 A;  1CZ4 A;  1L8F A;  1OA7 A;  2PNW A;  2WB1 A;  2G5D A;  3PLX B;  3GTG A;  1PQH A;  2VPW A;  2V3V A;  1R7R A;  4L48 A;  3GTP A;  2NAP A;  1S3S A;  2AE0 X;  1E5V A;  1TWG A;  2PIC A;  1SIW A;  2VUM A;  3X2K A;  3X2I A;  5T5M D;  1PYQ A;  5GLF A;  1R27 A;  1CR5 A;  3X2P A;  5C1B A;  5FTJ A;  1TWF A;  3SUM A;  5FTM A;  4QIW A;  3QC8 A;  3GTL A;  1E60 A;  3SUK A;  4AYB A;  5GLX A;  1PQE A;  2JIQ A;  2PMZ A;  1HD5 A;  4AAY A;  2YUJ A;  1BW3 A;  2KQA A;  3X2M A;  4FG4 A;  1WC2 A;  2BE5 D;  5EPP A;  1TWA A;  5GLY A;  1FDI A;  3O5A A;  4ENG A;  1TMO A;  2A68 D;  4AZD A;  2R93 A;  2WAQ A;  3HU2 A;  3SUJ A;  1E61 A;  1KQG A;  2JA5 A;  3X2J A;  1TWH A;  2O5J D;  1VC3 B;  4KDI A;  1BW4 A;  2JIP A;  3X2H A;  1WLF A;  4FER A;  4AOK B;  1AW8 B;  3GTK A;  5FTL A;  1PQF A;  3HU3 A;  2C45 A;  2A6E D;  1R9T A;  3IR5 A;  3HKZ A;  1I50 A;  3DMR A;  1KQF A;  2KI8 A;  5FTN A;  3SUL A;  1OA9 A;  3GTO A;  2NVX A;  1Y5I A;  2Y0S A;  1Y4Z A;  1YLE A;  2HCZ X;  1WCM A;  1E18 A;  4CRZ A;  4ZM7 A;  3TIW A;  3GTM A;  1DMR A;  2E2H A;  2GAE A;  1Y1W A;  1ZYR D;  1SMY D;  4GA5 A;  2NVY A;  5H4U A;  2VPX A;  3X2O A;  2PJJ A;  3M3G A;  2R7Z A;  3H0G A;  5DYI A;  2ENG A;  4FFT A;  4NOH A;  2R92 A;  2JIO A;  2VPZ A;  2JIR A;  4KO8 A;  1SFO A;  4CS0 A;  2JA7 A;  1PPY A;  1TWC A;  1IW7 D;  5T5I D;  4FG2 A;  3ML1 A;  1I3Q A;  1Q16 A;  3HU1 A;  1G8J A;  5GM9 A;  2IV2 X;  1PT0 A;  1ZC1 A;  2DMR A;  2G6G A;  2YU9 A;  1UHE A;  2E7Z A;  1K83 A;  2B63 A;  1CZ5 A;  1UHD A;  4D7Z B;  1QDN A;  1PYU B;  2CW0 D;  3FKI A;  3GTQ A;  1G8K A;  3GTJ A;  4DMR A;  1H5N A;  2JIM A;  3ENG A;  3CQZ A;  1YNN D;  1N10 A;  3X2G A;  2A6H D;  4RV0 A; 
#chains in the Genus database with same CATH homology
 2PJH B;  2JA6 A;  2PI8 A;  3CZB A;  3IR7 A;  1PT1 A;  2V45 A;  1E32 A;  3QWZ A;  1OGY A;  2E2I A;  4GA6 A;  1H0H A;  3OUG A;  1YNJ D;  1Y1V A;  2EEO B;  1QCS A;  4KOD A;  1AA6 A;  3QQ8 A;  2NYA A;  4AON B;  4C2M A;  1DMS A;  3QQ7 A;  3IR6 A;  4KDL A;  2VPY A;  1FDO A;  5FTK A;  3TM7 B;  3CF2 A;  4CRY G;  4KLN A;  5DYG A;  2A69 D;  5C18 A;  5B6C A;  1EU1 A;  1CZ4 A;  3PLX B;  2PNW A;  2WB1 A;  3GTG A;  2G5D A;  1PQH A;  2VPW A;  2V3V A;  1R7R A;  3GTP A;  2NAP A;  1S3S A;  2AE0 X;  1E5V A;  1TWG A;  2PIC A;  1SIW A;  2VUM A;  5T5M D;  1PYQ A;  5GLF A;  1R27 A;  1CR5 A;  5C1B A;  5FTJ A;  1TWF A;  5FTM A;  4QIW A;  3QC8 A;  3GTL A;  1E60 A;  4AYB A;  1PQE A;  2JIQ A;  2PMZ A;  4AAY A;  2YUJ A;  2BE5 D;  5EPP A;  1TWA A;  1FDI A;  3O5A A;  1TMO A;  2A68 D;  4AZD A;  2R93 A;  2WAQ A;  3HU2 A;  1KQG A;  1E61 A;  2JA5 A;  1TWH A;  2O5J D;  1VC3 B;  4KDI A;  2JIP A;  1WLF A;  4AOK B;  1AW8 B;  3GTK A;  5FTL A;  1PQF A;  3HU3 A;  2C45 A;  2A6E D;  1R9T A;  3IR5 A;  3HKZ A;  1I50 A;  3DMR A;  1KQF A;  2KI8 A;  5FTN A;  3GTO A;  2NVX A;  1Y5I A;  2Y0S A;  1Y4Z A;  1YLE A;  1WCM A;  1E18 A;  4CRZ A;  3TIW A;  3GTM A;  1DMR A;  2E2H A;  2GAE A;  1Y1W A;  1ZYR D;  1SMY D;  4GA5 A;  2NVY A;  2VPX A;  2PJJ A;  2R7Z A;  3H0G A;  5DYI A;  4NOH A;  2R92 A;  2JIO A;  2VPZ A;  2JIR A;  4KO8 A;  1SFO A;  4CS0 A;  2JA7 A;  1PPY A;  1TWC A;  1IW7 D;  5T5I D;  3ML1 A;  1I3Q A;  1Q16 A;  3HU1 A;  1G8J A;  2IV2 X;  1PT0 A;  1ZC1 A;  2DMR A;  2G6G A;  2YU9 A;  1UHE A;  2E7Z A;  1K83 A;  2B63 A;  1CZ5 A;  1UHD A;  4D7Z B;  1QDN A;  1PYU B;  2CW0 D;  3FKI A;  3GTQ A;  1G8K A;  3GTJ A;  4DMR A;  1H5N A;  2JIM A;  3CQZ A;  1YNN D;  2A6H D;  4RV0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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