1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords Aspartate 1-decarboxylase
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
3PLXB 1Y1VA 1Y4ZA 5T5ID 1R9TA 4KO8A 1SFOA 1PYUB 1Y1WA 4AZDA 1TWHA 3DMRA 3HU1A 4QIWA 1PQEA 1Y5IA 4CRZA 3QQ8A 1SIWA 3HU2A 2JA6A 2NVYA 3GTLA 1G8JA 1WCMA 2E7ZA 1E60A 2R93A 3FKIA 1TMOA 1QCSA 1PPYA 2C45A 3GTPA 4AONB 5DYGA 1TWGA 2PJHB 1VC3B 2VPWA 1CR5A 2NAPA 1FDOA 1TWFA 1Q16A 4D7ZB 5FTKA 1K83A 4CRYG 5FTLA 2E2IA 3GTQA 3TM7B 1CZ4A 2E2HA 1E5VA 3IR5A 1S3SA 3QWZA 4KODA 1UHEA 2NYAA 3HKZA 2JIPA 3H0GA 2VUMA 1CZ5A 1G8KA 3IR6A 1TWCA 3GTGA 5EPPA 2YU9A 2VPYA 3GTOA 2V3VA 1PQFA 3CQZA 1R7RA 1WLFA 1I50A 1R27A 2JIRA 2B63A 2NVXA 2DMRA 4KDLA 4KDIA 1KQFA 1PYQA 2JIMA 3O5AA 3TIWA 5B6CA 3OUGA 1OGYA 2R7ZA 3ML1A 4GA5A 1PQHA 2JA7A 1IW7D 2Y0SA 1KQGA 3GTJA 2WB1A 1UHDA 3GTMA 1YLEA 4DMRA 4GA6A 4KLNA 1E18A 1EU1A 2PMZA 2JA5A 2V45A 5FTMA 2WAQA 3IR7A 4RV0A 3QQ7A 3GTKA 1DMRA 1AW8B 4AOKB 1PT0A 4CS0A 3QC8A 5FTNA 1QDNA 2R92A 3CF2A 1E32A 2VPZA 1AA6A 3HU3A 2JIOA 4AYBA 1PT1A 5GLFA 1H0HA 2IV2X 1H5NA 5FTJA 5C18A 2JIQA 5T5MD 5DYIA 1E61A 4AAYA 5C1BA 1DMSA 1TWAA 1I3QA 2EEOB 4C2MA 1FDIA 2KI8A 2VPXA
chains in the Genus database with same CATH superfamily
3PLXB 1Y1VA 1Y4ZA 5T5ID 1R9TA 4KO8A 1YNND 1PYUB 1SFOA 1Y1WA 4AZDA 1TWHA 3DMRA 3HU1A 2PNWA 4QIWA 3X2MA 1PQEA 4JCWA 1Y5IA 4CRZA 2GAEA 3QQ8A 4JS7A 1SIWA 3HU2A 2JA6A 2NVYA 3GTLA 1G8JA 1WCMA 2E7ZA 1E60A 2R93A 3FKIA 1TMOA 5GM9A 1QCSA 1PPYA 2C45A 4JP7A 3GTPA 4AONB 5DYGA 1TWGA 2PJHB 5H4UA 1VC3B 2VPWA 1WC2A 1CR5A 2NAPA 1FDOA 1HD5A 1Q16A 1TWFA 4D7ZB 3SUKA 5GLYA 4JJOA 5FTKA 1K83A 4CRYG 5FTLA 2E2IA 3GTQA 3TM7B 1CZ4A 4NOHA 2E2HA 1E5VA 3IR5A 1S3SA 3QWZA 4KODA 4FFTA 1UHEA 1SMYD 3X2GA 2CW0D 3CZBA 1OA9A 2NYAA 4AVRA 3HKZA 2JIPA 3H0GA 2VUMA 1CZ5A 1ZC1A 1G8KA 3IR6A 1TWCA 2A6HD 3GTGA 5EPPA 2YU9A 2VPYA 3GTOA 2V3VA 2YUJA 2A6ED 1PQFA 3CQZA 1R7RA 3X2PA 1WLFA 2BE5D 1I50A 4FG4A 1ZYRD 3X2HA 1R27A 2JIRA 3X2OA 1N10A 2B63A 2NVXA 3M3GA 4ZM7A 3X2IA 2DMRA 4KDLA 4JP6A 4KDIA 3X2JA 1KQFA 1PYQA 2JIMA 3O5AA 3ENGA 3TIWA 5B6CA 3OUGA 1OGYA 2HCZX 2R7ZA 3SUJA 3SULA 3ML1A 3SUMA 2G5DA 4GA5A 1PQHA 1BW4A 2JA7A 1IW7D 2Y0SA 1KQGA 2PJJA 3GTJA 2WB1A 1UHDA 3GTMA 1YLEA 1BW3A 4DMRA 4GA6A 1OA7A 3X2NA 4KLNA 1E18A 1EU1A 1L8FA 2PMZA 4ENGA 2JA5A 2O5JD 2V45A 5FTMA 2A69D 1YNJD 2ENGA 2WAQA 3IR7A 2AE0X 4RV0A 4FERA 3QQ7A 3GTKA 1DMRA 1AW8B 2G6GA 4AOKB 2A68D 1PT0A 4CS0A 3QC8A 5FTNA 3X2KA 1QDNA 2R92A 2KQAA 3X2LA 3CF2A 1E32A 2VPZA 1AA6A 3HU3A 2JIOA 4AYBA 1PT1A 4FG2A 5GLFA 1H0HA 5GLXA 2IV2X 1H5NA 5FTJA 5C18A 2JIQA 5T5MD 3D30A 5DYIA 1E61A 4AAYA 2PI8A 5C1BA 1DMSA 1TWAA 2BH0A 2PICA 1I3QA 4L48A 2EEOB 4C2MA 1FDIA 2KI8A 2VPXA
chains in the Genus database with same CATH topology
3PLXB 1Y1VA 1Y4ZA 5T5ID 1R9TA 4KO8A 1YNND 1PYUB 1SFOA 1Y1WA 4AZDA 1TWHA 3DMRA 3HU1A 2PNWA 4QIWA 1PQEA 1Y5IA 4CRZA 2GAEA 3QQ8A 1SIWA 3HU2A 2JA6A 2NVYA 3GTLA 1G8JA 1WCMA 2E7ZA 1E60A 2R93A 3FKIA 1TMOA 1QCSA 1PPYA 2C45A 3GTPA 4AONB 5DYGA 1TWGA 2PJHB 1VC3B 2VPWA 1CR5A 2NAPA 1FDOA 1TWFA 1Q16A 4D7ZB 5FTKA 1K83A 4CRYG 5FTLA 2E2IA 3GTQA 3TM7B 1CZ4A 4NOHA 2E2HA 1E5VA 3IR5A 1S3SA 3QWZA 4KODA 1UHEA 1SMYD 2CW0D 3CZBA 2NYAA 3HKZA 2JIPA 3H0GA 2VUMA 1CZ5A 1ZC1A 1G8KA 3IR6A 1TWCA 2A6HD 3GTGA 5EPPA 2YU9A 2VPYA 3GTOA 2V3VA 2YUJA 2A6ED 1PQFA 3CQZA 1R7RA 1WLFA 2BE5D 1I50A 1ZYRD 1R27A 2JIRA 2B63A 2NVXA 2DMRA 4KDLA 4KDIA 1KQFA 1PYQA 2JIMA 3O5AA 3TIWA 5B6CA 3OUGA 1OGYA 2R7ZA 3ML1A 2G5DA 4GA5A 1PQHA 2JA7A 1IW7D 2Y0SA 1KQGA 2PJJA 3GTJA 2WB1A 1UHDA 3GTMA 1YLEA 4DMRA 4GA6A 4KLNA 1E18A 1EU1A 2PMZA 2JA5A 2O5JD 2V45A 5FTMA 2A69D 1YNJD 2WAQA 3IR7A 2AE0X 4RV0A 3QQ7A 3GTKA 1DMRA 1AW8B 2G6GA 4AOKB 2A68D 1PT0A 4CS0A 3QC8A 5FTNA 1QDNA 2R92A 3CF2A 1E32A 2VPZA 1AA6A 3HU3A 2JIOA 4AYBA 1PT1A 5GLFA 1H0HA 2IV2X 1H5NA 5FTJA 5C18A 2JIQA 5T5MD 5DYIA 1E61A 4AAYA 2PI8A 5C1BA 1DMSA 1TWAA 2PICA 1I3QA 2EEOB 4C2MA 1FDIA 2KI8A 2VPXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PLX B;  1Y1V A;  1Y4Z A;  5T5I D;  1R9T A;  4KO8 A;  1SFO A;  1PYU B;  1Y1W A;  4AZD A;  1TWH A;  3DMR A;  3HU1 A;  4QIW A;  1PQE A;  1Y5I A;  4CRZ A;  3QQ8 A;  1SIW A;  3HU2 A;  2JA6 A;  2NVY A;  3GTL A;  1G8J A;  1WCM A;  2E7Z A;  1E60 A;  2R93 A;  3FKI A;  1TMO A;  1QCS A;  1PPY A;  2C45 A;  3GTP A;  4AON B;  5DYG A;  1TWG A;  2PJH B;  1VC3 B;  2VPW A;  1CR5 A;  2NAP A;  1FDO A;  1TWF A;  1Q16 A;  4D7Z B;  5FTK A;  1K83 A;  4CRY G;  5FTL A;  2E2I A;  3GTQ A;  3TM7 B;  1CZ4 A;  2E2H A;  1E5V A;  3IR5 A;  1S3S A;  3QWZ A;  4KOD A;  1UHE A;  2NYA A;  3HKZ A;  2JIP A;  3H0G A;  2VUM A;  1CZ5 A;  1G8K A;  3IR6 A;  1TWC A;  3GTG A;  5EPP A;  2YU9 A;  2VPY A;  3GTO A;  2V3V A;  1PQF A;  3CQZ A;  1R7R A;  1WLF A;  1I50 A;  1R27 A;  2JIR A;  2B63 A;  2NVX A;  2DMR A;  4KDL A;  4KDI A;  1KQF A;  1PYQ A;  2JIM A;  3O5A A;  3TIW A;  5B6C A;  3OUG A;  1OGY A;  2R7Z A;  3ML1 A;  4GA5 A;  1PQH A;  2JA7 A;  1IW7 D;  2Y0S A;  1KQG A;  3GTJ A;  2WB1 A;  1UHD A;  3GTM A;  1YLE A;  4DMR A;  4GA6 A;  4KLN A;  1E18 A;  1EU1 A;  2PMZ A;  2JA5 A;  2V45 A;  5FTM A;  2WAQ A;  3IR7 A;  4RV0 A;  3QQ7 A;  3GTK A;  1DMR A;  1AW8 B;  4AOK B;  1PT0 A;  4CS0 A;  3QC8 A;  5FTN A;  1QDN A;  2R92 A;  3CF2 A;  1E32 A;  2VPZ A;  1AA6 A;  3HU3 A;  2JIO A;  4AYB A;  1PT1 A;  5GLF A;  1H0H A;  2IV2 X;  1H5N A;  5FTJ A;  5C18 A;  2JIQ A;  5T5M D;  5DYI A;  1E61 A;  4AAY A;  5C1B A;  1DMS A;  1TWA A;  1I3Q A;  2EEO B;  4C2M A;  1FDI A;  2KI8 A;  2VPX A; 
#chains in the Genus database with same CATH topology
 3PLX B;  1Y1V A;  1Y4Z A;  5T5I D;  1R9T A;  4KO8 A;  1YNN D;  1PYU B;  1SFO A;  1Y1W A;  4AZD A;  1TWH A;  3DMR A;  3HU1 A;  2PNW A;  4QIW A;  3X2M A;  1PQE A;  4JCW A;  1Y5I A;  4CRZ A;  2GAE A;  3QQ8 A;  4JS7 A;  1SIW A;  3HU2 A;  2JA6 A;  2NVY A;  3GTL A;  1G8J A;  1WCM A;  2E7Z A;  1E60 A;  2R93 A;  3FKI A;  1TMO A;  5GM9 A;  1QCS A;  1PPY A;  2C45 A;  4JP7 A;  3GTP A;  4AON B;  5DYG A;  1TWG A;  2PJH B;  5H4U A;  1VC3 B;  2VPW A;  1WC2 A;  1CR5 A;  2NAP A;  1FDO A;  1HD5 A;  1Q16 A;  1TWF A;  4D7Z B;  3SUK A;  5GLY A;  4JJO A;  5FTK A;  1K83 A;  4CRY G;  5FTL A;  2E2I A;  3GTQ A;  3TM7 B;  1CZ4 A;  4NOH A;  2E2H A;  1E5V A;  3IR5 A;  1S3S A;  3QWZ A;  4KOD A;  4FFT A;  1UHE A;  1SMY D;  3X2G A;  2CW0 D;  3CZB A;  1OA9 A;  2NYA A;  4AVR A;  3HKZ A;  2JIP A;  3H0G A;  2VUM A;  1CZ5 A;  1ZC1 A;  1G8K A;  3IR6 A;  1TWC A;  2A6H D;  3GTG A;  5EPP A;  2YU9 A;  2VPY A;  3GTO A;  2V3V A;  2YUJ A;  2A6E D;  1PQF A;  3CQZ A;  1R7R A;  3X2P A;  1WLF A;  2BE5 D;  1I50 A;  4FG4 A;  1ZYR D;  3X2H A;  1R27 A;  2JIR A;  3X2O A;  1N10 A;  2B63 A;  2NVX A;  3M3G A;  4ZM7 A;  3X2I A;  2DMR A;  4KDL A;  4JP6 A;  4KDI A;  3X2J A;  1KQF A;  1PYQ A;  2JIM A;  3O5A A;  3ENG A;  3TIW A;  5B6C A;  3OUG A;  1OGY A;  2HCZ X;  2R7Z A;  3SUJ A;  3SUL A;  3ML1 A;  3SUM A;  2G5D A;  4GA5 A;  1PQH A;  1BW4 A;  2JA7 A;  1IW7 D;  2Y0S A;  1KQG A;  2PJJ A;  3GTJ A;  2WB1 A;  1UHD A;  3GTM A;  1YLE A;  1BW3 A;  4DMR A;  4GA6 A;  1OA7 A;  3X2N A;  4KLN A;  1E18 A;  1EU1 A;  1L8F A;  2PMZ A;  4ENG A;  2JA5 A;  2O5J D;  2V45 A;  5FTM A;  2A69 D;  1YNJ D;  2ENG A;  2WAQ A;  3IR7 A;  2AE0 X;  4RV0 A;  4FER A;  3QQ7 A;  3GTK A;  1DMR A;  1AW8 B;  2G6G A;  4AOK B;  2A68 D;  1PT0 A;  4CS0 A;  3QC8 A;  5FTN A;  3X2K A;  1QDN A;  2R92 A;  2KQA A;  3X2L A;  3CF2 A;  1E32 A;  2VPZ A;  1AA6 A;  3HU3 A;  2JIO A;  4AYB A;  1PT1 A;  4FG2 A;  5GLF A;  1H0H A;  5GLX A;  2IV2 X;  1H5N A;  5FTJ A;  5C18 A;  2JIQ A;  5T5M D;  3D30 A;  5DYI A;  1E61 A;  4AAY A;  2PI8 A;  5C1B A;  1DMS A;  1TWA A;  2BH0 A;  2PIC A;  1I3Q A;  4L48 A;  2EEO B;  4C2M A;  1FDI A;  2KI8 A;  2VPX A; 
#chains in the Genus database with same CATH homology
 3PLX B;  1Y1V A;  1Y4Z A;  5T5I D;  1R9T A;  4KO8 A;  1YNN D;  1PYU B;  1SFO A;  1Y1W A;  4AZD A;  1TWH A;  3DMR A;  3HU1 A;  2PNW A;  4QIW A;  1PQE A;  1Y5I A;  4CRZ A;  2GAE A;  3QQ8 A;  1SIW A;  3HU2 A;  2JA6 A;  2NVY A;  3GTL A;  1G8J A;  1WCM A;  2E7Z A;  1E60 A;  2R93 A;  3FKI A;  1TMO A;  1QCS A;  1PPY A;  2C45 A;  3GTP A;  4AON B;  5DYG A;  1TWG A;  2PJH B;  1VC3 B;  2VPW A;  1CR5 A;  2NAP A;  1FDO A;  1TWF A;  1Q16 A;  4D7Z B;  5FTK A;  1K83 A;  4CRY G;  5FTL A;  2E2I A;  3GTQ A;  3TM7 B;  1CZ4 A;  4NOH A;  2E2H A;  1E5V A;  3IR5 A;  1S3S A;  3QWZ A;  4KOD A;  1UHE A;  1SMY D;  2CW0 D;  3CZB A;  2NYA A;  3HKZ A;  2JIP A;  3H0G A;  2VUM A;  1CZ5 A;  1ZC1 A;  1G8K A;  3IR6 A;  1TWC A;  2A6H D;  3GTG A;  5EPP A;  2YU9 A;  2VPY A;  3GTO A;  2V3V A;  2YUJ A;  2A6E D;  1PQF A;  3CQZ A;  1R7R A;  1WLF A;  2BE5 D;  1I50 A;  1ZYR D;  1R27 A;  2JIR A;  2B63 A;  2NVX A;  2DMR A;  4KDL A;  4KDI A;  1KQF A;  1PYQ A;  2JIM A;  3O5A A;  3TIW A;  5B6C A;  3OUG A;  1OGY A;  2R7Z A;  3ML1 A;  2G5D A;  4GA5 A;  1PQH A;  2JA7 A;  1IW7 D;  2Y0S A;  1KQG A;  2PJJ A;  3GTJ A;  2WB1 A;  1UHD A;  3GTM A;  1YLE A;  4DMR A;  4GA6 A;  4KLN A;  1E18 A;  1EU1 A;  2PMZ A;  2JA5 A;  2O5J D;  2V45 A;  5FTM A;  2A69 D;  1YNJ D;  2WAQ A;  3IR7 A;  2AE0 X;  4RV0 A;  3QQ7 A;  3GTK A;  1DMR A;  1AW8 B;  2G6G A;  4AOK B;  2A68 D;  1PT0 A;  4CS0 A;  3QC8 A;  5FTN A;  1QDN A;  2R92 A;  3CF2 A;  1E32 A;  2VPZ A;  1AA6 A;  3HU3 A;  2JIO A;  4AYB A;  1PT1 A;  5GLF A;  1H0H A;  2IV2 X;  1H5N A;  5FTJ A;  5C18 A;  2JIQ A;  5T5M D;  5DYI A;  1E61 A;  4AAY A;  2PI8 A;  5C1B A;  1DMS A;  1TWA A;  2PIC A;  1I3Q A;  2EEO B;  4C2M A;  1FDI A;  2KI8 A;  2VPX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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