1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords Aspartate 1-decarboxylase
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
4AONB 2EEOB 1E32A 5T5MD 1PQHA 1R9TA 4CRZA 1Y1VA 1PT0A 1TWFA 3HKZA 3HU2A 4KDLA 3QQ8A 4GA6A 1UHDA 1CZ5A 1IW7D 1TWAA 2E7ZA 2JIMA 1TMOA 2Y0SA 3IR7A 1CZ4A 3IR5A 2VPZA 5B6CA 1E61A 2R92A 3QC8A 5FTMA 2E2IA 2VUMA 1Y5IA 3QWZA 1H5NA 1E18A 2JIQA 4AYBA 1YLEA 4KO8A 5FTKA 3GTGA 2JIPA 2NAPA 2PMZA 3ML1A 1TWCA 4AAYA 1K83A 1H0HA 3QQ7A 1KQFA 4GA5A 3H0GA 2NVYA 3GTKA 2WB1A 1DMRA 4DMRA 1S3SA 3HU3A 1Y1WA 1R7RA 1I3QA 3TIWA 1G8JA 2NVXA 2JIRA 3GTJA 4CS0A 2JA5A 5DYGA 1VC3B 4C2MA 2IV2X 1EU1A 3FKIA 4RV0A 3DMRA 2V3VA 5GLFA 2R7ZA 1PQFA 1DMSA 1FDIA 4KODA 2NYAA 4QIWA 2WAQA 2PJHB 2VPXA 3CF2A 1AA6A 4KDIA 5FTNA 2VPYA 2JA7A 4KLNA 3GTQA 3GTPA 2DMRA 3GTOA 2KI8A 1UHEA 5FTLA 3PLXB 3HU1A 2E2HA 2V45A 1WLFA 4D7ZB 3TM7B 3OUGA 1OGYA 1PYQA 1G8KA 1SFOA 1Q16A 2JA6A 1CR5A 1E5VA 1TWGA 5T5ID 3GTLA 1QCSA 1FDOA 3IR6A 1PPYA 5C1BA 1QDNA 2JIOA 5FTJA 1KQGA 2B63A 5DYIA 1I50A 1R27A 2R93A 5C18A 4CRYG 4AOKB 4AZDA 3GTMA 1WCMA 2VPWA 1PT1A 1AW8B 3CQZA 1PYUB 3O5AA 1PQEA 1Y4ZA 2C45A 1TWHA 1E60A 5EPPA 1SIWA 2YU9A
chains in the Genus database with same CATH superfamily
4AONB 2EEOB 1E32A 4JS7A 5T5MD 1PQHA 5H4UA 1R9TA 4CRZA 1Y1VA 1PT0A 1TWFA 3HKZA 3HU2A 4KDLA 3QQ8A 1YNND 4GA6A 1UHDA 5GM9A 1IW7D 1CZ5A 1TWAA 2E7ZA 2JIMA 1TMOA 1BW3A 2Y0SA 3IR7A 1CZ4A 3IR5A 2VPZA 3X2JA 5B6CA 1E61A 2R92A 3QC8A 5FTMA 2E2IA 2VUMA 3X2KA 1Y5IA 4FG2A 2PNWA 3QWZA 1H5NA 1E18A 2JIQA 4AYBA 1YLEA 4KO8A 5FTKA 3GTGA 2JIPA 2NAPA 2PMZA 3ML1A 1TWCA 4AAYA 1WC2A 1K83A 1H0HA 2A69D 3QQ7A 1KQFA 2YUJA 2PI8A 2G5DA 4GA5A 3H0GA 1BW4A 2NVYA 3GTKA 3X2IA 2WB1A 1DMRA 4DMRA 1S3SA 2HCZX 3HU3A 1Y1WA 1R7RA 4NOHA 1I3QA 3TIWA 1G8JA 2NVXA 2G6GA 2JIRA 2A6ED 3GTJA 4L48A 4CS0A 2JA5A 5DYGA 1VC3B 4C2MA 2IV2X 1EU1A 3FKIA 4RV0A 3DMRA 2V3VA 3X2MA 5GLFA 3X2PA 1SMYD 2R7ZA 4FFTA 1PQFA 1DMSA 1FDIA 4KODA 2NYAA 4QIWA 2WAQA 2PJHB 2VPXA 1OA9A 3CF2A 1AA6A 4KDIA 4FERA 5FTNA 2VPYA 2JA7A 2GAEA 1ZC1A 4KLNA 3X2LA 3GTQA 2DMRA 3GTPA 3GTOA 2KI8A 1UHEA 5FTLA 3D30A 3PLXB 3HU1A 2E2HA 1L8FA 4ZM7A 2V45A 2PJJA 1WLFA 4FG4A 4D7ZB 3TM7B 2ENGA 3OUGA 2KQAA 1OA7A 1OGYA 1PYQA 1G8KA 3SUKA 2CW0D 4JJOA 5GLXA 3X2GA 3M3GA 1SFOA 1Q16A 1N10A 2JA6A 1CR5A 1E5VA 1TWGA 5T5ID 3GTLA 1QCSA 1FDOA 3ENGA 3IR6A 1PPYA 2BE5D 1QDNA 5C1BA 3X2NA 2JIOA 4JP6A 2O5JD 5FTJA 3SUJA 1KQGA 2B63A 5DYIA 3SUMA 1I50A 2A68D 1R27A 2A6HD 3CZBA 2R93A 5C18A 4CRYG 3X2HA 4AOKB 4AZDA 1YNJD 1HD5A 4JP7A 2BH0A 3GTMA 1WCMA 2VPWA 1PT1A 1AW8B 3CQZA 1PYUB 1ZYRD 4JCWA 3O5AA 1PQEA 5GLYA 2PICA 1Y4ZA 2AE0X 1TWHA 2C45A 3X2OA 4AVRA 1E60A 5EPPA 1SIWA 4ENGA 3SULA 2YU9A
chains in the Genus database with same CATH topology
4AONB 2EEOB 1E32A 5T5MD 1PQHA 1R9TA 4CRZA 1Y1VA 1PT0A 1TWFA 3HKZA 3HU2A 4KDLA 3QQ8A 1YNND 4GA6A 1UHDA 1CZ5A 1IW7D 1TWAA 2E7ZA 2JIMA 1TMOA 2Y0SA 3IR7A 1CZ4A 3IR5A 2VPZA 5B6CA 1E61A 2R92A 3QC8A 5FTMA 2E2IA 2VUMA 1Y5IA 2PNWA 3QWZA 1H5NA 1E18A 2JIQA 4AYBA 1YLEA 4KO8A 5FTKA 3GTGA 2JIPA 2NAPA 2PMZA 3ML1A 1TWCA 4AAYA 1K83A 1H0HA 2A69D 3QQ7A 1KQFA 2YUJA 2PI8A 2G5DA 4GA5A 3H0GA 2NVYA 3GTKA 2WB1A 1DMRA 4DMRA 1S3SA 3HU3A 1Y1WA 1R7RA 4NOHA 1I3QA 3TIWA 1G8JA 2NVXA 2G6GA 2JIRA 2A6ED 3GTJA 4CS0A 2JA5A 5DYGA 1VC3B 4C2MA 2IV2X 1EU1A 3FKIA 4RV0A 3DMRA 2V3VA 5GLFA 1SMYD 2R7ZA 1PQFA 1DMSA 1FDIA 4KODA 2NYAA 4QIWA 2WAQA 2PJHB 2VPXA 3CF2A 1AA6A 4KDIA 5FTNA 2VPYA 2JA7A 2GAEA 1ZC1A 4KLNA 3GTQA 3GTPA 2DMRA 3GTOA 2KI8A 1UHEA 5FTLA 3PLXB 3HU1A 2E2HA 2V45A 2PJJA 1WLFA 4D7ZB 3TM7B 3OUGA 1OGYA 1PYQA 1G8KA 2CW0D 1SFOA 1Q16A 2JA6A 1CR5A 1E5VA 1TWGA 5T5ID 3GTLA 1QCSA 1FDOA 3IR6A 1PPYA 2BE5D 1QDNA 5C1BA 2JIOA 2O5JD 5FTJA 1KQGA 2B63A 5DYIA 1I50A 2A68D 1R27A 2A6HD 3CZBA 2R93A 5C18A 4CRYG 4AOKB 4AZDA 1YNJD 3GTMA 1WCMA 2VPWA 1PT1A 1AW8B 3CQZA 1PYUB 1ZYRD 3O5AA 1PQEA 2PICA 1Y4ZA 2AE0X 1TWHA 2C45A 1E60A 5EPPA 1SIWA 2YU9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AON B;  2EEO B;  1E32 A;  5T5M D;  1PQH A;  1R9T A;  4CRZ A;  1Y1V A;  1PT0 A;  1TWF A;  3HKZ A;  3HU2 A;  4KDL A;  3QQ8 A;  4GA6 A;  1UHD A;  1CZ5 A;  1IW7 D;  1TWA A;  2E7Z A;  2JIM A;  1TMO A;  2Y0S A;  3IR7 A;  1CZ4 A;  3IR5 A;  2VPZ A;  5B6C A;  1E61 A;  2R92 A;  3QC8 A;  5FTM A;  2E2I A;  2VUM A;  1Y5I A;  3QWZ A;  1H5N A;  1E18 A;  2JIQ A;  4AYB A;  1YLE A;  4KO8 A;  5FTK A;  3GTG A;  2JIP A;  2NAP A;  2PMZ A;  3ML1 A;  1TWC A;  4AAY A;  1K83 A;  1H0H A;  3QQ7 A;  1KQF A;  4GA5 A;  3H0G A;  2NVY A;  3GTK A;  2WB1 A;  1DMR A;  4DMR A;  1S3S A;  3HU3 A;  1Y1W A;  1R7R A;  1I3Q A;  3TIW A;  1G8J A;  2NVX A;  2JIR A;  3GTJ A;  4CS0 A;  2JA5 A;  5DYG A;  1VC3 B;  4C2M A;  2IV2 X;  1EU1 A;  3FKI A;  4RV0 A;  3DMR A;  2V3V A;  5GLF A;  2R7Z A;  1PQF A;  1DMS A;  1FDI A;  4KOD A;  2NYA A;  4QIW A;  2WAQ A;  2PJH B;  2VPX A;  3CF2 A;  1AA6 A;  4KDI A;  5FTN A;  2VPY A;  2JA7 A;  4KLN A;  3GTQ A;  3GTP A;  2DMR A;  3GTO A;  2KI8 A;  1UHE A;  5FTL A;  3PLX B;  3HU1 A;  2E2H A;  2V45 A;  1WLF A;  4D7Z B;  3TM7 B;  3OUG A;  1OGY A;  1PYQ A;  1G8K A;  1SFO A;  1Q16 A;  2JA6 A;  1CR5 A;  1E5V A;  1TWG A;  5T5I D;  3GTL A;  1QCS A;  1FDO A;  3IR6 A;  1PPY A;  5C1B A;  1QDN A;  2JIO A;  5FTJ A;  1KQG A;  2B63 A;  5DYI A;  1I50 A;  1R27 A;  2R93 A;  5C18 A;  4CRY G;  4AOK B;  4AZD A;  3GTM A;  1WCM A;  2VPW A;  1PT1 A;  1AW8 B;  3CQZ A;  1PYU B;  3O5A A;  1PQE A;  1Y4Z A;  2C45 A;  1TWH A;  1E60 A;  5EPP A;  1SIW A;  2YU9 A; 
#chains in the Genus database with same CATH topology
 4AON B;  2EEO B;  1E32 A;  4JS7 A;  5T5M D;  1PQH A;  5H4U A;  1R9T A;  4CRZ A;  1Y1V A;  1PT0 A;  1TWF A;  3HKZ A;  3HU2 A;  4KDL A;  3QQ8 A;  1YNN D;  4GA6 A;  1UHD A;  5GM9 A;  1IW7 D;  1CZ5 A;  1TWA A;  2E7Z A;  2JIM A;  1TMO A;  1BW3 A;  2Y0S A;  3IR7 A;  1CZ4 A;  3IR5 A;  2VPZ A;  3X2J A;  5B6C A;  1E61 A;  2R92 A;  3QC8 A;  5FTM A;  2E2I A;  2VUM A;  3X2K A;  1Y5I A;  4FG2 A;  2PNW A;  3QWZ A;  1H5N A;  1E18 A;  2JIQ A;  4AYB A;  1YLE A;  4KO8 A;  5FTK A;  3GTG A;  2JIP A;  2NAP A;  2PMZ A;  3ML1 A;  1TWC A;  4AAY A;  1WC2 A;  1K83 A;  1H0H A;  2A69 D;  3QQ7 A;  1KQF A;  2YUJ A;  2PI8 A;  2G5D A;  4GA5 A;  3H0G A;  1BW4 A;  2NVY A;  3GTK A;  3X2I A;  2WB1 A;  1DMR A;  4DMR A;  1S3S A;  2HCZ X;  3HU3 A;  1Y1W A;  1R7R A;  4NOH A;  1I3Q A;  3TIW A;  1G8J A;  2NVX A;  2G6G A;  2JIR A;  2A6E D;  3GTJ A;  4L48 A;  4CS0 A;  2JA5 A;  5DYG A;  1VC3 B;  4C2M A;  2IV2 X;  1EU1 A;  3FKI A;  4RV0 A;  3DMR A;  2V3V A;  3X2M A;  5GLF A;  3X2P A;  1SMY D;  2R7Z A;  4FFT A;  1PQF A;  1DMS A;  1FDI A;  4KOD A;  2NYA A;  4QIW A;  2WAQ A;  2PJH B;  2VPX A;  1OA9 A;  3CF2 A;  1AA6 A;  4KDI A;  4FER A;  5FTN A;  2VPY A;  2JA7 A;  2GAE A;  1ZC1 A;  4KLN A;  3X2L A;  3GTQ A;  2DMR A;  3GTP A;  3GTO A;  2KI8 A;  1UHE A;  5FTL A;  3D30 A;  3PLX B;  3HU1 A;  2E2H A;  1L8F A;  4ZM7 A;  2V45 A;  2PJJ A;  1WLF A;  4FG4 A;  4D7Z B;  3TM7 B;  2ENG A;  3OUG A;  2KQA A;  1OA7 A;  1OGY A;  1PYQ A;  1G8K A;  3SUK A;  2CW0 D;  4JJO A;  5GLX A;  3X2G A;  3M3G A;  1SFO A;  1Q16 A;  1N10 A;  2JA6 A;  1CR5 A;  1E5V A;  1TWG A;  5T5I D;  3GTL A;  1QCS A;  1FDO A;  3ENG A;  3IR6 A;  1PPY A;  2BE5 D;  1QDN A;  5C1B A;  3X2N A;  2JIO A;  4JP6 A;  2O5J D;  5FTJ A;  3SUJ A;  1KQG A;  2B63 A;  5DYI A;  3SUM A;  1I50 A;  2A68 D;  1R27 A;  2A6H D;  3CZB A;  2R93 A;  5C18 A;  4CRY G;  3X2H A;  4AOK B;  4AZD A;  1YNJ D;  1HD5 A;  4JP7 A;  2BH0 A;  3GTM A;  1WCM A;  2VPW A;  1PT1 A;  1AW8 B;  3CQZ A;  1PYU B;  1ZYR D;  4JCW A;  3O5A A;  1PQE A;  5GLY A;  2PIC A;  1Y4Z A;  2AE0 X;  1TWH A;  2C45 A;  3X2O A;  4AVR A;  1E60 A;  5EPP A;  1SIW A;  4ENG A;  3SUL A;  2YU9 A; 
#chains in the Genus database with same CATH homology
 4AON B;  2EEO B;  1E32 A;  5T5M D;  1PQH A;  1R9T A;  4CRZ A;  1Y1V A;  1PT0 A;  1TWF A;  3HKZ A;  3HU2 A;  4KDL A;  3QQ8 A;  1YNN D;  4GA6 A;  1UHD A;  1CZ5 A;  1IW7 D;  1TWA A;  2E7Z A;  2JIM A;  1TMO A;  2Y0S A;  3IR7 A;  1CZ4 A;  3IR5 A;  2VPZ A;  5B6C A;  1E61 A;  2R92 A;  3QC8 A;  5FTM A;  2E2I A;  2VUM A;  1Y5I A;  2PNW A;  3QWZ A;  1H5N A;  1E18 A;  2JIQ A;  4AYB A;  1YLE A;  4KO8 A;  5FTK A;  3GTG A;  2JIP A;  2NAP A;  2PMZ A;  3ML1 A;  1TWC A;  4AAY A;  1K83 A;  1H0H A;  2A69 D;  3QQ7 A;  1KQF A;  2YUJ A;  2PI8 A;  2G5D A;  4GA5 A;  3H0G A;  2NVY A;  3GTK A;  2WB1 A;  1DMR A;  4DMR A;  1S3S A;  3HU3 A;  1Y1W A;  1R7R A;  4NOH A;  1I3Q A;  3TIW A;  1G8J A;  2NVX A;  2G6G A;  2JIR A;  2A6E D;  3GTJ A;  4CS0 A;  2JA5 A;  5DYG A;  1VC3 B;  4C2M A;  2IV2 X;  1EU1 A;  3FKI A;  4RV0 A;  3DMR A;  2V3V A;  5GLF A;  1SMY D;  2R7Z A;  1PQF A;  1DMS A;  1FDI A;  4KOD A;  2NYA A;  4QIW A;  2WAQ A;  2PJH B;  2VPX A;  3CF2 A;  1AA6 A;  4KDI A;  5FTN A;  2VPY A;  2JA7 A;  2GAE A;  1ZC1 A;  4KLN A;  3GTQ A;  3GTP A;  2DMR A;  3GTO A;  2KI8 A;  1UHE A;  5FTL A;  3PLX B;  3HU1 A;  2E2H A;  2V45 A;  2PJJ A;  1WLF A;  4D7Z B;  3TM7 B;  3OUG A;  1OGY A;  1PYQ A;  1G8K A;  2CW0 D;  1SFO A;  1Q16 A;  2JA6 A;  1CR5 A;  1E5V A;  1TWG A;  5T5I D;  3GTL A;  1QCS A;  1FDO A;  3IR6 A;  1PPY A;  2BE5 D;  1QDN A;  5C1B A;  2JIO A;  2O5J D;  5FTJ A;  1KQG A;  2B63 A;  5DYI A;  1I50 A;  2A68 D;  1R27 A;  2A6H D;  3CZB A;  2R93 A;  5C18 A;  4CRY G;  4AOK B;  4AZD A;  1YNJ D;  3GTM A;  1WCM A;  2VPW A;  1PT1 A;  1AW8 B;  3CQZ A;  1PYU B;  1ZYR D;  3O5A A;  1PQE A;  2PIC A;  1Y4Z A;  2AE0 X;  1TWH A;  2C45 A;  1E60 A;  5EPP A;  1SIW A;  2YU9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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