1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords Aspartate 1-decarboxylase
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
2JIRA 1G8JA 2NAPA 5B6CA 1R7RA 5T5MD 2EEOB 2JA6A 1TWCA 5GLFA 1FDIA 1PYQA 3GTKA 2PJHB 3GTLA 2R93A 1WLFA 4AAYA 1E61A 1E32A 3GTPA 1PQEA 3QC8A 2B63A 5FTMA 3GTMA 3QQ7A 1EU1A 3ML1A 1IW7D 5FTKA 3HU3A 3GTGA 1UHEA 3CF2A 5FTJA 1AA6A 2VPYA 1DMRA 3IR7A 2V45A 1QCSA 4KODA 1PPYA 2JA5A 2R7ZA 2NYAA 1I3QA 2Y0SA 1SIWA 1PYUB 1TWGA 3HKZA 3QWZA 2C45A 4DMRA 2WAQA 1H0HA 2WB1A 2VUMA 5C1BA 3O5AA 5FTNA 1KQGA 4AYBA 1Y4ZA 5DYIA 1UHDA 4CRYG 2VPZA 4D7ZB 1PT0A 4AOKB 1R9TA 1K83A 3GTJA 2NVYA 2VPXA 3QQ8A 4C2MA 2E2IA 1DMSA 4KDLA 3PLXB 3TIWA 2R92A 4AZDA 1TWHA 1SFOA 1S3SA 1Y1WA 1I50A 3IR6A 2JIQA 5T5ID 4QIWA 4RV0A 2JA7A 2JIOA 4CRZA 4KLNA 1G8KA 3TM7B 1PQFA 1KQFA 1TWAA 2DMRA 2E7ZA 4GA5A 1Q16A 2YU9A 1H5NA 2VPWA 3DMRA 3IR5A 1E18A 2JIMA 1TMOA 1AW8B 4AONB 3CQZA 5DYGA 1Y5IA 2IV2X 2E2HA 1TWFA 2V3VA 5FTLA 3HU2A 1OGYA 2JIPA 3FKIA 2PMZA 5C18A 3GTQA 4KO8A 1WCMA 1E5VA 1PQHA 4CS0A 4GA6A 1Y1VA 3GTOA 5EPPA 1FDOA 1QDNA 3OUGA 1R27A 3H0GA 1PT1A 1E60A 4KDIA 1YLEA 1VC3B 1CZ5A 3HU1A 1CZ4A 2NVXA 1CR5A 2KI8A
chains in the Genus database with same CATH superfamily
2JIRA 3X2NA 1G8JA 3SUJA 2ENGA 2NAPA 5B6CA 1R7RA 5T5MD 2EEOB 2JA6A 4JJOA 1TWCA 5GLFA 1FDIA 1PYQA 2PI8A 2PJHB 3GTKA 1BW3A 3GTLA 2R93A 1WLFA 4AAYA 1E61A 1E32A 3GTPA 1PQEA 3QC8A 4L48A 3X2OA 5FTMA 3X2KA 3QQ7A 3GTMA 2B63A 1EU1A 3ML1A 1IW7D 4JP7A 5GM9A 3SUMA 2PJJA 3HU3A 5FTKA 4AVRA 3GTGA 1OA7A 1UHEA 3CF2A 5FTJA 1AA6A 2VPYA 1DMRA 3IR7A 3ENGA 2V45A 1QCSA 3SUKA 3X2JA 2PICA 4KODA 1PPYA 2JA5A 2R7ZA 2NYAA 1I3QA 2Y0SA 1SIWA 1L8FA 1PYUB 1TWGA 2A69D 3HKZA 3QWZA 2PNWA 2C45A 1N10A 2A68D 4DMRA 2WAQA 1H0HA 2WB1A 2HCZX 2VUMA 5GLXA 3O5AA 3X2IA 2CW0D 5C1BA 5FTNA 1KQGA 4AYBA 1Y4ZA 5DYIA 1UHDA 4CRYG 1YNND 2VPZA 2G6GA 2A6ED 1PT0A 4JS7A 4AOKB 2NVYA 4D7ZB 2VPXA 1R9TA 3GTJA 2BE5D 3QQ8A 4C2MA 1DMSA 2E2IA 4KDLA 3PLXB 3TIWA 2R92A 4AZDA 2NVXA 1TWHA 1YNJD 1SFOA 4FG4A 1S3SA 2O5JD 4ENGA 1Y1WA 2AE0X 1I50A 3X2MA 4JP6A 4NOHA 1HD5A 3IR6A 2JIQA 3M3GA 5T5ID 2GAEA 4QIWA 4RV0A 2JA7A 2JIOA 4CRZA 4KLNA 1G8KA 3TM7B 1PQFA 1WC2A 4ZM7A 1KQFA 1K83A 1BW4A 1TWAA 2DMRA 2E7ZA 4GA5A 1ZC1A 1Q16A 5H4UA 2YU9A 1H5NA 2VPWA 3DMRA 3IR5A 1E18A 4FFTA 2JIMA 1TMOA 3X2HA 1AW8B 4AONB 2A6HD 3CQZA 5DYGA 5GLYA 4FG2A 1Y5IA 2IV2X 3X2PA 2E2HA 2YUJA 1TWFA 2V3VA 5FTLA 3HU2A 1OGYA 2JIPA 3FKIA 2PMZA 1ZYRD 5C18A 3GTQA 4KO8A 1WCMA 1E5VA 1PQHA 4JCWA 4CS0A 4GA6A 1Y1VA 3GTOA 4FERA 5EPPA 1FDOA 3CZBA 3X2LA 2G5DA 1QDNA 3OUGA 1R27A 2BH0A 1PT1A 3H0GA 1E60A 3SULA 4KDIA 1SMYD 1YLEA 1VC3B 1OA9A 2KQAA 1CZ5A 3X2GA 3HU1A 1CZ4A 3D30A 1CR5A 2KI8A
chains in the Genus database with same CATH topology
2JIRA 1G8JA 2NAPA 5B6CA 1R7RA 5T5MD 2EEOB 2JA6A 1TWCA 5GLFA 1FDIA 1PYQA 2PI8A 2PJHB 3GTKA 3GTLA 2R93A 1WLFA 4AAYA 1E61A 1E32A 3GTPA 1PQEA 3QC8A 2B63A 5FTMA 3GTMA 3QQ7A 1EU1A 3ML1A 1IW7D 2PJJA 3HU3A 5FTKA 3GTGA 1UHEA 3CF2A 5FTJA 1AA6A 2VPYA 1DMRA 3IR7A 2V45A 1QCSA 2PICA 4KODA 1PPYA 2JA5A 2R7ZA 2NYAA 1I3QA 2Y0SA 1SIWA 1PYUB 1TWGA 2A69D 3HKZA 3QWZA 2PNWA 2C45A 2A68D 4DMRA 2WAQA 1H0HA 2WB1A 2VUMA 5C1BA 3O5AA 2CW0D 5FTNA 1KQGA 4AYBA 1Y4ZA 5DYIA 1UHDA 4CRYG 1YNND 2VPZA 2G6GA 2A6ED 1PT0A 4AOKB 4D7ZB 2NVYA 1R9TA 2VPXA 1K83A 3GTJA 2BE5D 3QQ8A 4C2MA 1DMSA 2E2IA 4KDLA 3PLXB 3TIWA 2R92A 4AZDA 1TWHA 1YNJD 1SFOA 1S3SA 2O5JD 1Y1WA 2AE0X 1I50A 4NOHA 3IR6A 2JIQA 5T5ID 2GAEA 4QIWA 4RV0A 2JA7A 2JIOA 4CRZA 4KLNA 1G8KA 3TM7B 1PQFA 1KQFA 1TWAA 2DMRA 2E7ZA 4GA5A 1ZC1A 1Q16A 2YU9A 1H5NA 2VPWA 3DMRA 3IR5A 1E18A 2JIMA 1TMOA 1AW8B 4AONB 2A6HD 3CQZA 5DYGA 1Y5IA 2IV2X 2E2HA 2YUJA 1TWFA 2V3VA 5FTLA 3HU2A 1OGYA 2JIPA 3FKIA 2PMZA 1ZYRD 5C18A 3GTQA 4KO8A 1WCMA 1E5VA 1PQHA 4CS0A 4GA6A 1Y1VA 3GTOA 5EPPA 1FDOA 3CZBA 2G5DA 1QDNA 3OUGA 1R27A 3H0GA 1PT1A 1E60A 4KDIA 1SMYD 1YLEA 1VC3B 1CZ5A 3HU1A 1CZ4A 2NVXA 1CR5A 2KI8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JIR A;  1G8J A;  2NAP A;  5B6C A;  1R7R A;  5T5M D;  2EEO B;  2JA6 A;  1TWC A;  5GLF A;  1FDI A;  1PYQ A;  3GTK A;  2PJH B;  3GTL A;  2R93 A;  1WLF A;  4AAY A;  1E61 A;  1E32 A;  3GTP A;  1PQE A;  3QC8 A;  2B63 A;  5FTM A;  3GTM A;  3QQ7 A;  1EU1 A;  3ML1 A;  1IW7 D;  5FTK A;  3HU3 A;  3GTG A;  1UHE A;  3CF2 A;  5FTJ A;  1AA6 A;  2VPY A;  1DMR A;  3IR7 A;  2V45 A;  1QCS A;  4KOD A;  1PPY A;  2JA5 A;  2R7Z A;  2NYA A;  1I3Q A;  2Y0S A;  1SIW A;  1PYU B;  1TWG A;  3HKZ A;  3QWZ A;  2C45 A;  4DMR A;  2WAQ A;  1H0H A;  2WB1 A;  2VUM A;  5C1B A;  3O5A A;  5FTN A;  1KQG A;  4AYB A;  1Y4Z A;  5DYI A;  1UHD A;  4CRY G;  2VPZ A;  4D7Z B;  1PT0 A;  4AOK B;  1R9T A;  1K83 A;  3GTJ A;  2NVY A;  2VPX A;  3QQ8 A;  4C2M A;  2E2I A;  1DMS A;  4KDL A;  3PLX B;  3TIW A;  2R92 A;  4AZD A;  1TWH A;  1SFO A;  1S3S A;  1Y1W A;  1I50 A;  3IR6 A;  2JIQ A;  5T5I D;  4QIW A;  4RV0 A;  2JA7 A;  2JIO A;  4CRZ A;  4KLN A;  1G8K A;  3TM7 B;  1PQF A;  1KQF A;  1TWA A;  2DMR A;  2E7Z A;  4GA5 A;  1Q16 A;  2YU9 A;  1H5N A;  2VPW A;  3DMR A;  3IR5 A;  1E18 A;  2JIM A;  1TMO A;  1AW8 B;  4AON B;  3CQZ A;  5DYG A;  1Y5I A;  2IV2 X;  2E2H A;  1TWF A;  2V3V A;  5FTL A;  3HU2 A;  1OGY A;  2JIP A;  3FKI A;  2PMZ A;  5C18 A;  3GTQ A;  4KO8 A;  1WCM A;  1E5V A;  1PQH A;  4CS0 A;  4GA6 A;  1Y1V A;  3GTO A;  5EPP A;  1FDO A;  1QDN A;  3OUG A;  1R27 A;  3H0G A;  1PT1 A;  1E60 A;  4KDI A;  1YLE A;  1VC3 B;  1CZ5 A;  3HU1 A;  1CZ4 A;  2NVX A;  1CR5 A;  2KI8 A; 
#chains in the Genus database with same CATH topology
 2JIR A;  3X2N A;  1G8J A;  3SUJ A;  2ENG A;  2NAP A;  5B6C A;  1R7R A;  5T5M D;  2EEO B;  2JA6 A;  4JJO A;  1TWC A;  5GLF A;  1FDI A;  1PYQ A;  2PI8 A;  2PJH B;  3GTK A;  1BW3 A;  3GTL A;  2R93 A;  1WLF A;  4AAY A;  1E61 A;  1E32 A;  3GTP A;  1PQE A;  3QC8 A;  4L48 A;  3X2O A;  5FTM A;  3X2K A;  3QQ7 A;  3GTM A;  2B63 A;  1EU1 A;  3ML1 A;  1IW7 D;  4JP7 A;  5GM9 A;  3SUM A;  2PJJ A;  3HU3 A;  5FTK A;  4AVR A;  3GTG A;  1OA7 A;  1UHE A;  3CF2 A;  5FTJ A;  1AA6 A;  2VPY A;  1DMR A;  3IR7 A;  3ENG A;  2V45 A;  1QCS A;  3SUK A;  3X2J A;  2PIC A;  4KOD A;  1PPY A;  2JA5 A;  2R7Z A;  2NYA A;  1I3Q A;  2Y0S A;  1SIW A;  1L8F A;  1PYU B;  1TWG A;  2A69 D;  3HKZ A;  3QWZ A;  2PNW A;  2C45 A;  1N10 A;  2A68 D;  4DMR A;  2WAQ A;  1H0H A;  2WB1 A;  2HCZ X;  2VUM A;  5GLX A;  3O5A A;  3X2I A;  2CW0 D;  5C1B A;  5FTN A;  1KQG A;  4AYB A;  1Y4Z A;  5DYI A;  1UHD A;  4CRY G;  1YNN D;  2VPZ A;  2G6G A;  2A6E D;  1PT0 A;  4JS7 A;  4AOK B;  2NVY A;  4D7Z B;  2VPX A;  1R9T A;  3GTJ A;  2BE5 D;  3QQ8 A;  4C2M A;  1DMS A;  2E2I A;  4KDL A;  3PLX B;  3TIW A;  2R92 A;  4AZD A;  2NVX A;  1TWH A;  1YNJ D;  1SFO A;  4FG4 A;  1S3S A;  2O5J D;  4ENG A;  1Y1W A;  2AE0 X;  1I50 A;  3X2M A;  4JP6 A;  4NOH A;  1HD5 A;  3IR6 A;  2JIQ A;  3M3G A;  5T5I D;  2GAE A;  4QIW A;  4RV0 A;  2JA7 A;  2JIO A;  4CRZ A;  4KLN A;  1G8K A;  3TM7 B;  1PQF A;  1WC2 A;  4ZM7 A;  1KQF A;  1K83 A;  1BW4 A;  1TWA A;  2DMR A;  2E7Z A;  4GA5 A;  1ZC1 A;  1Q16 A;  5H4U A;  2YU9 A;  1H5N A;  2VPW A;  3DMR A;  3IR5 A;  1E18 A;  4FFT A;  2JIM A;  1TMO A;  3X2H A;  1AW8 B;  4AON B;  2A6H D;  3CQZ A;  5DYG A;  5GLY A;  4FG2 A;  1Y5I A;  2IV2 X;  3X2P A;  2E2H A;  2YUJ A;  1TWF A;  2V3V A;  5FTL A;  3HU2 A;  1OGY A;  2JIP A;  3FKI A;  2PMZ A;  1ZYR D;  5C18 A;  3GTQ A;  4KO8 A;  1WCM A;  1E5V A;  1PQH A;  4JCW A;  4CS0 A;  4GA6 A;  1Y1V A;  3GTO A;  4FER A;  5EPP A;  1FDO A;  3CZB A;  3X2L A;  2G5D A;  1QDN A;  3OUG A;  1R27 A;  2BH0 A;  1PT1 A;  3H0G A;  1E60 A;  3SUL A;  4KDI A;  1SMY D;  1YLE A;  1VC3 B;  1OA9 A;  2KQA A;  1CZ5 A;  3X2G A;  3HU1 A;  1CZ4 A;  3D30 A;  1CR5 A;  2KI8 A; 
#chains in the Genus database with same CATH homology
 2JIR A;  1G8J A;  2NAP A;  5B6C A;  1R7R A;  5T5M D;  2EEO B;  2JA6 A;  1TWC A;  5GLF A;  1FDI A;  1PYQ A;  2PI8 A;  2PJH B;  3GTK A;  3GTL A;  2R93 A;  1WLF A;  4AAY A;  1E61 A;  1E32 A;  3GTP A;  1PQE A;  3QC8 A;  2B63 A;  5FTM A;  3GTM A;  3QQ7 A;  1EU1 A;  3ML1 A;  1IW7 D;  2PJJ A;  3HU3 A;  5FTK A;  3GTG A;  1UHE A;  3CF2 A;  5FTJ A;  1AA6 A;  2VPY A;  1DMR A;  3IR7 A;  2V45 A;  1QCS A;  2PIC A;  4KOD A;  1PPY A;  2JA5 A;  2R7Z A;  2NYA A;  1I3Q A;  2Y0S A;  1SIW A;  1PYU B;  1TWG A;  2A69 D;  3HKZ A;  3QWZ A;  2PNW A;  2C45 A;  2A68 D;  4DMR A;  2WAQ A;  1H0H A;  2WB1 A;  2VUM A;  5C1B A;  3O5A A;  2CW0 D;  5FTN A;  1KQG A;  4AYB A;  1Y4Z A;  5DYI A;  1UHD A;  4CRY G;  1YNN D;  2VPZ A;  2G6G A;  2A6E D;  1PT0 A;  4AOK B;  4D7Z B;  2NVY A;  1R9T A;  2VPX A;  1K83 A;  3GTJ A;  2BE5 D;  3QQ8 A;  4C2M A;  1DMS A;  2E2I A;  4KDL A;  3PLX B;  3TIW A;  2R92 A;  4AZD A;  1TWH A;  1YNJ D;  1SFO A;  1S3S A;  2O5J D;  1Y1W A;  2AE0 X;  1I50 A;  4NOH A;  3IR6 A;  2JIQ A;  5T5I D;  2GAE A;  4QIW A;  4RV0 A;  2JA7 A;  2JIO A;  4CRZ A;  4KLN A;  1G8K A;  3TM7 B;  1PQF A;  1KQF A;  1TWA A;  2DMR A;  2E7Z A;  4GA5 A;  1ZC1 A;  1Q16 A;  2YU9 A;  1H5N A;  2VPW A;  3DMR A;  3IR5 A;  1E18 A;  2JIM A;  1TMO A;  1AW8 B;  4AON B;  2A6H D;  3CQZ A;  5DYG A;  1Y5I A;  2IV2 X;  2E2H A;  2YUJ A;  1TWF A;  2V3V A;  5FTL A;  3HU2 A;  1OGY A;  2JIP A;  3FKI A;  2PMZ A;  1ZYR D;  5C18 A;  3GTQ A;  4KO8 A;  1WCM A;  1E5V A;  1PQH A;  4CS0 A;  4GA6 A;  1Y1V A;  3GTO A;  5EPP A;  1FDO A;  3CZB A;  2G5D A;  1QDN A;  3OUG A;  1R27 A;  3H0G A;  1PT1 A;  1E60 A;  4KDI A;  1SMY D;  1YLE A;  1VC3 B;  1CZ5 A;  3HU1 A;  1CZ4 A;  2NVX A;  1CR5 A;  2KI8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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