1PYQA

Unprocessed aspartate decarboxylase mutant, with alanine inserted at position 24
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
120
structure length
120
Chain Sequence
PRGSMIRTMLQGKLHRVKVTHADLHYEAGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords Aspartate 1-decarboxylase
total genus 38
structure length 120
sequence length 120
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pyqA00
2E2IA 1PQHA 1E61A 4AONB 5FTMA 1G8JA 4D7ZB 4CRZA 2E7ZA 1TWCA 1PYUB 1AA6A 1H5NA 3GTGA 3GTJA 2DMRA 1WLFA 1PQFA 4AYBA 2NAPA 1VC3B 3IR7A 5FTNA 2B63A 1TWAA 3IR5A 3TM7B 2C45A 2EEOB 2R92A 1E60A 1PT0A 2YU9A 1E32A 3GTPA 2VPWA 1TMOA 1G8KA 1R7RA 1FDIA 3H0GA 2R7ZA 3GTLA 2PJHB 3CF2A 1R27A 1Y4ZA 3ML1A 1QDNA 5DYGA 4RV0A 2IV2X 1H0HA 1UHEA 1EU1A 1UHDA 1CZ4A 2VPZA 4AAYA 3QWZA 1Y5IA 2NYAA 5EPPA 3GTQA 2WB1A 1E18A 1DMRA 1WCMA 2NVYA 3GTKA 2E2HA 2VUMA 2JIPA 1E5VA 1PPYA 2NVXA 2JIQA 1CZ5A 1KQFA 1DMSA 1KQGA 3GTOA 4AOKB 1R9TA 1TWFA 5FTKA 1Y1WA 1FDOA 1TWHA 5FTJA 1QCSA 3QQ8A 3QC8A 3O5AA 1Q16A 2JA5A 4KO8A 3DMRA 2JIOA 1TWGA 1AW8B 1CR5A 2Y0SA 3TIWA 4KDLA 5FTLA 5C18A 4QIWA 1IW7D 2V3VA 3HU1A 3PLXB 4GA5A 5T5MD 5GLFA 4KLNA 3OUGA 5T5ID 3FKIA 2JIRA 4DMRA 1YLEA 1SIWA 1S3SA 4GA6A 2KI8A 1PQEA 1PT1A 1K83A 3IR6A 2VPYA 2V45A 4KDIA 5C1BA 4C2MA 3HKZA 3HU2A 2VPXA 1I3QA 1PYQA 4CRYG 4AZDA 2JA6A 1SFOA 3CQZA 3HU3A 2WAQA 3QQ7A 3GTMA 4KODA 1I50A 2JA7A 1OGYA 1Y1VA 2JIMA 2R93A 4CS0A 5B6CA 2PMZA 5DYIA
chains in the Genus database with same CATH superfamily
2E2IA 1WC2A 1PQHA 1E61A 4AONB 5FTMA 1G8JA 4D7ZB 4CRZA 2E7ZA 3X2KA 1TWCA 1PYUB 1AA6A 1H5NA 3GTGA 3GTJA 2DMRA 1WLFA 1PQFA 4AYBA 5H4UA 1YNJD 2NAPA 1VC3B 1YNND 3IR7A 5FTNA 4AVRA 2B63A 1TWAA 3IR5A 3TM7B 2PJJA 2C45A 4JJOA 5GLXA 2EEOB 2R92A 1E60A 1PT0A 4JP7A 2YU9A 1E32A 3GTPA 2O5JD 2VPWA 1TMOA 2A69D 4FERA 1G8KA 1R7RA 1FDIA 3H0GA 2R7ZA 4FG4A 3GTLA 2PJHB 3CF2A 1R27A 1Y4ZA 3ML1A 1QDNA 5DYGA 4JCWA 2PNWA 4RV0A 2IV2X 1H0HA 5GM9A 1UHEA 1EU1A 1UHDA 2YUJA 1CZ4A 2VPZA 4AAYA 2AE0X 3QWZA 3X2GA 1Y5IA 2NYAA 4ENGA 5EPPA 3X2LA 4CS0A 3GTQA 1HD5A 4FG2A 2KQAA 2WB1A 1E18A 1DMRA 1WCMA 2NVYA 3GTKA 2E2HA 2VUMA 2JIPA 3X2PA 1E5VA 1PPYA 1SMYD 2NVXA 2JIQA 1CZ5A 1KQFA 2PICA 1DMSA 1KQGA 3GTOA 4AOKB 1R9TA 1TWFA 5FTKA 1Y1WA 1FDOA 1TWHA 5FTJA 2A6HD 1QCSA 3QQ8A 3X2OA 2ENGA 3QC8A 3X2MA 3O5AA 1Q16A 2BH0A 3CZBA 2JA5A 2PI8A 4KO8A 3DMRA 3SUJA 1BW4A 2JIOA 3X2JA 3SUMA 1TWGA 1AW8B 1CR5A 2Y0SA 3TIWA 4KDLA 5FTLA 4ZM7A 4NOHA 5C18A 4QIWA 1IW7D 2V3VA 3HU1A 3M3GA 3PLXB 4GA5A 5T5MD 5GLFA 2A68D 4KLNA 3OUGA 5T5ID 1OA7A 3FKIA 2JIRA 4DMRA 1YLEA 1SIWA 1S3SA 4GA6A 2KI8A 1OA9A 1PQEA 1PT1A 4JP6A 3IR6A 1K83A 2VPYA 2V45A 3D30A 4KDIA 1N10A 1ZYRD 2BE5D 5C1BA 4JS7A 4C2MA 2G6GA 3X2IA 3HKZA 3HU2A 2VPXA 1I3QA 1L8FA 1PYQA 4CRYG 4AZDA 2JA6A 1SFOA 3X2NA 5GLYA 2G5DA 3CQZA 3HU3A 4L48A 3SULA 2A6ED 2WAQA 4FFTA 3X2HA 3QQ7A 3GTMA 4KODA 1I50A 2JA7A 1BW3A 1OGYA 1Y1VA 2JIMA 2HCZX 2R93A 1ZC1A 2GAEA 3ENGA 5B6CA 2PMZA 3SUKA 2CW0D 5DYIA
chains in the Genus database with same CATH topology
2E2IA 1PQHA 1E61A 4AONB 5FTMA 1G8JA 4D7ZB 4CRZA 2E7ZA 1TWCA 1PYUB 1AA6A 1H5NA 3GTGA 3GTJA 2DMRA 1WLFA 1PQFA 4AYBA 1YNJD 2NAPA 1VC3B 1YNND 3IR7A 5FTNA 2B63A 1TWAA 3IR5A 3TM7B 2PJJA 2C45A 2EEOB 2R92A 1E60A 1PT0A 2YU9A 1E32A 3GTPA 2O5JD 2VPWA 1TMOA 2A69D 1G8KA 1R7RA 1FDIA 3H0GA 2R7ZA 3GTLA 2PJHB 3CF2A 1R27A 1Y4ZA 3ML1A 1QDNA 5DYGA 2PNWA 4RV0A 2IV2X 1H0HA 1UHEA 1EU1A 1UHDA 2YUJA 1CZ4A 2VPZA 4AAYA 2AE0X 3QWZA 1Y5IA 2NYAA 5EPPA 3GTQA 2WB1A 1E18A 1DMRA 1WCMA 2NVYA 3GTKA 2E2HA 2VUMA 2JIPA 1E5VA 1PPYA 1SMYD 2NVXA 2JIQA 1CZ5A 1KQFA 2PICA 1DMSA 1KQGA 3GTOA 4AOKB 1R9TA 1TWFA 5FTKA 1Y1WA 1FDOA 1TWHA 5FTJA 2A6HD 1QCSA 3QQ8A 3QC8A 3O5AA 1Q16A 3CZBA 2JA5A 2PI8A 4KO8A 3DMRA 2JIOA 1TWGA 1AW8B 1CR5A 2Y0SA 3TIWA 4KDLA 5FTLA 4NOHA 5C18A 4QIWA 1IW7D 2V3VA 3HU1A 3PLXB 4GA5A 5T5MD 5GLFA 2A68D 4KLNA 3OUGA 5T5ID 3FKIA 2JIRA 4DMRA 1YLEA 1SIWA 1S3SA 4GA6A 2KI8A 1PQEA 1PT1A 1K83A 3IR6A 2VPYA 2V45A 4KDIA 1ZYRD 2BE5D 5C1BA 4C2MA 2G6GA 3HKZA 3HU2A 2VPXA 1I3QA 1PYQA 4CRYG 4AZDA 2JA6A 1SFOA 2G5DA 3CQZA 3HU3A 2A6ED 2WAQA 3QQ7A 3GTMA 4KODA 1I50A 2JA7A 1OGYA 1Y1VA 2JIMA 2R93A 1ZC1A 2GAEA 4CS0A 5B6CA 2PMZA 2CW0D 5DYIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E2I A;  1PQH A;  1E61 A;  4AON B;  5FTM A;  1G8J A;  4D7Z B;  4CRZ A;  2E7Z A;  1TWC A;  1PYU B;  1AA6 A;  1H5N A;  3GTG A;  3GTJ A;  2DMR A;  1WLF A;  1PQF A;  4AYB A;  2NAP A;  1VC3 B;  3IR7 A;  5FTN A;  2B63 A;  1TWA A;  3IR5 A;  3TM7 B;  2C45 A;  2EEO B;  2R92 A;  1E60 A;  1PT0 A;  2YU9 A;  1E32 A;  3GTP A;  2VPW A;  1TMO A;  1G8K A;  1R7R A;  1FDI A;  3H0G A;  2R7Z A;  3GTL A;  2PJH B;  3CF2 A;  1R27 A;  1Y4Z A;  3ML1 A;  1QDN A;  5DYG A;  4RV0 A;  2IV2 X;  1H0H A;  1UHE A;  1EU1 A;  1UHD A;  1CZ4 A;  2VPZ A;  4AAY A;  3QWZ A;  1Y5I A;  2NYA A;  5EPP A;  3GTQ A;  2WB1 A;  1E18 A;  1DMR A;  1WCM A;  2NVY A;  3GTK A;  2E2H A;  2VUM A;  2JIP A;  1E5V A;  1PPY A;  2NVX A;  2JIQ A;  1CZ5 A;  1KQF A;  1DMS A;  1KQG A;  3GTO A;  4AOK B;  1R9T A;  1TWF A;  5FTK A;  1Y1W A;  1FDO A;  1TWH A;  5FTJ A;  1QCS A;  3QQ8 A;  3QC8 A;  3O5A A;  1Q16 A;  2JA5 A;  4KO8 A;  3DMR A;  2JIO A;  1TWG A;  1AW8 B;  1CR5 A;  2Y0S A;  3TIW A;  4KDL A;  5FTL A;  5C18 A;  4QIW A;  1IW7 D;  2V3V A;  3HU1 A;  3PLX B;  4GA5 A;  5T5M D;  5GLF A;  4KLN A;  3OUG A;  5T5I D;  3FKI A;  2JIR A;  4DMR A;  1YLE A;  1SIW A;  1S3S A;  4GA6 A;  2KI8 A;  1PQE A;  1PT1 A;  1K83 A;  3IR6 A;  2VPY A;  2V45 A;  4KDI A;  5C1B A;  4C2M A;  3HKZ A;  3HU2 A;  2VPX A;  1I3Q A;  1PYQ A;  4CRY G;  4AZD A;  2JA6 A;  1SFO A;  3CQZ A;  3HU3 A;  2WAQ A;  3QQ7 A;  3GTM A;  4KOD A;  1I50 A;  2JA7 A;  1OGY A;  1Y1V A;  2JIM A;  2R93 A;  4CS0 A;  5B6C A;  2PMZ A;  5DYI A; 
#chains in the Genus database with same CATH topology
 2E2I A;  1WC2 A;  1PQH A;  1E61 A;  4AON B;  5FTM A;  1G8J A;  4D7Z B;  4CRZ A;  2E7Z A;  3X2K A;  1TWC A;  1PYU B;  1AA6 A;  1H5N A;  3GTG A;  3GTJ A;  2DMR A;  1WLF A;  1PQF A;  4AYB A;  5H4U A;  1YNJ D;  2NAP A;  1VC3 B;  1YNN D;  3IR7 A;  5FTN A;  4AVR A;  2B63 A;  1TWA A;  3IR5 A;  3TM7 B;  2PJJ A;  2C45 A;  4JJO A;  5GLX A;  2EEO B;  2R92 A;  1E60 A;  1PT0 A;  4JP7 A;  2YU9 A;  1E32 A;  3GTP A;  2O5J D;  2VPW A;  1TMO A;  2A69 D;  4FER A;  1G8K A;  1R7R A;  1FDI A;  3H0G A;  2R7Z A;  4FG4 A;  3GTL A;  2PJH B;  3CF2 A;  1R27 A;  1Y4Z A;  3ML1 A;  1QDN A;  5DYG A;  4JCW A;  2PNW A;  4RV0 A;  2IV2 X;  1H0H A;  5GM9 A;  1UHE A;  1EU1 A;  1UHD A;  2YUJ A;  1CZ4 A;  2VPZ A;  4AAY A;  2AE0 X;  3QWZ A;  3X2G A;  1Y5I A;  2NYA A;  4ENG A;  5EPP A;  3X2L A;  4CS0 A;  3GTQ A;  1HD5 A;  4FG2 A;  2KQA A;  2WB1 A;  1E18 A;  1DMR A;  1WCM A;  2NVY A;  3GTK A;  2E2H A;  2VUM A;  2JIP A;  3X2P A;  1E5V A;  1PPY A;  1SMY D;  2NVX A;  2JIQ A;  1CZ5 A;  1KQF A;  2PIC A;  1DMS A;  1KQG A;  3GTO A;  4AOK B;  1R9T A;  1TWF A;  5FTK A;  1Y1W A;  1FDO A;  1TWH A;  5FTJ A;  2A6H D;  1QCS A;  3QQ8 A;  3X2O A;  2ENG A;  3QC8 A;  3X2M A;  3O5A A;  1Q16 A;  2BH0 A;  3CZB A;  2JA5 A;  2PI8 A;  4KO8 A;  3DMR A;  3SUJ A;  1BW4 A;  2JIO A;  3X2J A;  3SUM A;  1TWG A;  1AW8 B;  1CR5 A;  2Y0S A;  3TIW A;  4KDL A;  5FTL A;  4ZM7 A;  4NOH A;  5C18 A;  4QIW A;  1IW7 D;  2V3V A;  3HU1 A;  3M3G A;  3PLX B;  4GA5 A;  5T5M D;  5GLF A;  2A68 D;  4KLN A;  3OUG A;  5T5I D;  1OA7 A;  3FKI A;  2JIR A;  4DMR A;  1YLE A;  1SIW A;  1S3S A;  4GA6 A;  2KI8 A;  1OA9 A;  1PQE A;  1PT1 A;  4JP6 A;  3IR6 A;  1K83 A;  2VPY A;  2V45 A;  3D30 A;  4KDI A;  1N10 A;  1ZYR D;  2BE5 D;  5C1B A;  4JS7 A;  4C2M A;  2G6G A;  3X2I A;  3HKZ A;  3HU2 A;  2VPX A;  1I3Q A;  1L8F A;  1PYQ A;  4CRY G;  4AZD A;  2JA6 A;  1SFO A;  3X2N A;  5GLY A;  2G5D A;  3CQZ A;  3HU3 A;  4L48 A;  3SUL A;  2A6E D;  2WAQ A;  4FFT A;  3X2H A;  3QQ7 A;  3GTM A;  4KOD A;  1I50 A;  2JA7 A;  1BW3 A;  1OGY A;  1Y1V A;  2JIM A;  2HCZ X;  2R93 A;  1ZC1 A;  2GAE A;  3ENG A;  5B6C A;  2PMZ A;  3SUK A;  2CW0 D;  5DYI A; 
#chains in the Genus database with same CATH homology
 2E2I A;  1PQH A;  1E61 A;  4AON B;  5FTM A;  1G8J A;  4D7Z B;  4CRZ A;  2E7Z A;  1TWC A;  1PYU B;  1AA6 A;  1H5N A;  3GTG A;  3GTJ A;  2DMR A;  1WLF A;  1PQF A;  4AYB A;  1YNJ D;  2NAP A;  1VC3 B;  1YNN D;  3IR7 A;  5FTN A;  2B63 A;  1TWA A;  3IR5 A;  3TM7 B;  2PJJ A;  2C45 A;  2EEO B;  2R92 A;  1E60 A;  1PT0 A;  2YU9 A;  1E32 A;  3GTP A;  2O5J D;  2VPW A;  1TMO A;  2A69 D;  1G8K A;  1R7R A;  1FDI A;  3H0G A;  2R7Z A;  3GTL A;  2PJH B;  3CF2 A;  1R27 A;  1Y4Z A;  3ML1 A;  1QDN A;  5DYG A;  2PNW A;  4RV0 A;  2IV2 X;  1H0H A;  1UHE A;  1EU1 A;  1UHD A;  2YUJ A;  1CZ4 A;  2VPZ A;  4AAY A;  2AE0 X;  3QWZ A;  1Y5I A;  2NYA A;  5EPP A;  3GTQ A;  2WB1 A;  1E18 A;  1DMR A;  1WCM A;  2NVY A;  3GTK A;  2E2H A;  2VUM A;  2JIP A;  1E5V A;  1PPY A;  1SMY D;  2NVX A;  2JIQ A;  1CZ5 A;  1KQF A;  2PIC A;  1DMS A;  1KQG A;  3GTO A;  4AOK B;  1R9T A;  1TWF A;  5FTK A;  1Y1W A;  1FDO A;  1TWH A;  5FTJ A;  2A6H D;  1QCS A;  3QQ8 A;  3QC8 A;  3O5A A;  1Q16 A;  3CZB A;  2JA5 A;  2PI8 A;  4KO8 A;  3DMR A;  2JIO A;  1TWG A;  1AW8 B;  1CR5 A;  2Y0S A;  3TIW A;  4KDL A;  5FTL A;  4NOH A;  5C18 A;  4QIW A;  1IW7 D;  2V3V A;  3HU1 A;  3PLX B;  4GA5 A;  5T5M D;  5GLF A;  2A68 D;  4KLN A;  3OUG A;  5T5I D;  3FKI A;  2JIR A;  4DMR A;  1YLE A;  1SIW A;  1S3S A;  4GA6 A;  2KI8 A;  1PQE A;  1PT1 A;  1K83 A;  3IR6 A;  2VPY A;  2V45 A;  4KDI A;  1ZYR D;  2BE5 D;  5C1B A;  4C2M A;  2G6G A;  3HKZ A;  3HU2 A;  2VPX A;  1I3Q A;  1PYQ A;  4CRY G;  4AZD A;  2JA6 A;  1SFO A;  2G5D A;  3CQZ A;  3HU3 A;  2A6E D;  2WAQ A;  3QQ7 A;  3GTM A;  4KOD A;  1I50 A;  2JA7 A;  1OGY A;  1Y1V A;  2JIM A;  2R93 A;  1ZC1 A;  2GAE A;  4CS0 A;  5B6C A;  2PMZ A;  2CW0 D;  5DYI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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