1KLIL

Cofactor-and substrate-assisted activation of factor viia
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
61
structure length
61
Chain Sequence
HKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Uninhibited Factor VIIa Link its Cofactor and Substrate-assisted Activation to Specific Interactions
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords factor VIIa
total genus 12
structure length 61
sequence length 61
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2001-12-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1kliL00
4RRYA 1NPEB 1IOXA 1W8BL 3M36L 2RNLA 4YT6L 4JZFL 2F9BL 1EPHA 5JB9E 3OLUA 1PFXL 3NJPC 3KQCL 1DQBA 1EPJA 1FJSL 1N1IA 4NGAL 3NT1A 1ADXA 3HPTA 1NZIA 1YUFA 2XC4L 4Z0LA 1U8CB 2VH6B 4ZXXL 2W2QE 3IITB 1IQLL 2P3FN 1JL9A 1YO8A 2P3UA 4XLWA 1HX2A 3LTFB 1G2LB 3F6UL 4X8TL 5L2YL 4JYVL 1G1TA 1YUKB 1XDTR 1YUGA 3HO5A 3HS5A 5L2ZL 2TGFA 5KIRA 1XKAL 3HO3A 1WU1B 2FLGA 5IKRA 3CENL 2K2TA 1UZQA 4BDWA 5IKQA 2FZZL 5IKTA 4AQTA 1IQJL 1DVAL 2PUQL 3K9XA 2Y81B 1FFMA 1LPZA 4OTYA 3ZYJB 1G1RA 2W2ME 3KL6B 1CVWL 2FLBL 3GCXE 2BOXA 1EQGA 4MMZB 2FD6A 2BQ6A 2J4IB 4Z6AL 2KL7A 2J2UB 2RA0L 1CCVA 1CQEA 2BQWA 2P94L 2DDUA 3C9AC 1KSNB 1IQML 3NTBA 1IP0A 3RR3A 1EBVA 3SOBB 1DX5I 2W86A 2P26A 4MMYB 1KIGL 3P5BL 1HT8A 3SW2A 3KQDL 4Y71B 1HCGB 1EQHA 4BXSA 2H9EL 2W2PE 2Y80B 2BOUA 1X7AL 4COXA 5CISA 1HREA 1IQNL 1EGFA 1IGXA 5F1AA 2W3IB 1ATBA 1U67A 3ZYIB 2PHBB 1IOEL 2WPKE 3M37L 1F0SB 2VJ3A 4O02B 2J34B 2EI6B 2VVVL 2W2OE 3N8YB 1IVOC 4Y7AB 4ISIL 5COXA 2KV4A 1DDXA 1MOXC 2WPIE 1UZKA 2WFXB 5E8DA 1EPGA 1HAEA 5EGMB 3HO4A 4RRXA 1NQLB 5JVYA 2UWPB 1PGEA 2YGOA 4TGFA 4XBMA 1IQGL 2WG4B 1K37A 4G1MB 2WPLE 3ELAL 1CEJA 2W2NE 3TH3L 1W7XL 3F1SB 2Y5HL 4YT7L 2MGRA 2WYJB 3TBDA 2GD4A 3N8YA 1F7MA 4X8VL 3QMOA 3N8ZA 2Q1JB 4X8UL 3OLTA 1IQKL 2VVUL 1IQHL 2CJIB 4ISHL 2BQ7A 3LC5B 1BF9A 1TPGA 1HRFA 1L5GB 3Q3KB 2I9BA 2BOKL 2FLRL 3FFGL 3TZIA 3LAQA 4LORA 3EGFA 5CKNA 1FAKL 2BMGA 3BPSE 2EI7B 2NPRA 5JBBE 3TGFA 1OB1C 2EI8B 2J95B 4C16A 4NA9L 1CX2A 2WYGB 4CSYA 2VH0B 3TK5B 1P9JA 1JV2B 5IKVA 2Y7XB 4Y76B 4BTTA 3CFWA 1FSBA 1Q4GA 2OYUP 2Y7ZB 1EMNA 3LN0A 4JZEL 3H5CB 3MDLA 1IGZA 1HZ8A 3LIWB 5KN5C 4RRZA 3HS7A 2VWLL 2XC5L 1NFUB 4JYUL 2RHPA 2WFTA 1M1XB 2XBXL 4YZUB 4JZDL 3N8XA 4D0FA 3ASIA 1LPKA 4PH9A 3TK6B 2B7DL 3CA7A 4E1GA 1UZPA 2P3TA 3V65B 2WPJE 5FDQA 4RS0A 2KB9A 4BDXA 1IQIL 5JB8E 1NFYB 2XBVL 1PTHA 1F0RB 1G1SA 3KQBL 3CS7L 4ZXYL 4Y79B 4O1ZA 1K36A 2J38B 3SOVA 3BT2A 1C5MF 4Y6DB 3GCWE 4OTJA 1IQEL 3KCGL 1EZQB 1URKA 2VWNL 4D0EA 5CKQA 1CCFA 1FF7A 3V64C 3SOQA 2P93L 4BTIA 1ATAA 3ZYGA 2WPME 2XBYL 1P0SL 2MHPA 2VWMK 4X8SL 4XL1A 1HT5A 3QCWA 2P95L 1TLEA 2PR3B 1F7EA 3ENSA 3N8VA 1DIYA 2P28B 1G1QA 4M11A 1MQ5L 2XBWL 1NFWB 4BXWA 2BOHA 1XKBA 3R05A 1AUTL 2Y82B 1PRHA 3LC3B 2Y38A 3Q7DA 3HS6A 4Z0KB 1I0UA 2XC0L 3KRKA 1FAXL 4ZH8B 2OYEP 1NFXB 3PGHA 1MQ6L 1IJQA 1SZBA 2WPHE 3FBYA 1L3YA 2WG3C 1APOA 2UWLB 4FM5A 2M74A 2BO2A 5CKMA 1A3PA 4Y7BB 1Z6EL 1CVUA 1JBUL 3NTGA 3GISX 4RRWA 1B9WA 1LPGA 2MGPA 1GK5A 4NG9L 5L30L 3U73A 1ATDA 3N8WB 1WHEA 2I9AA 2JKHL 2VWOL 5K0HB 4CUDA 3MQEA 5JBAE 1HAFA 4LMFA 2YGPA 4ZHAB 4MMXB 1HJ7A 2D1JB 2K2SB 6COXA 4D90A 3BT1A 1LQDA 2Y5GL 1FE2A 1QFKL 2ADXA 3FCSB 3QH0A 5F19A 5I46L 2VVCK 2AYLA 2W26B 1EAIC 4ZAEB 1UZJA 2P3FL 2W3KB 5JW1A 3U7UG 3LTGD 3POYA 1APQA 4BTUA 3LN1A 1NT0A 1ZAQA 1Z6CA 4CUEA 1J9CL 1KLJL 1PXXA 1N7DA 1WHFA 3N8WA 3KK6A 4A7IA 5JBCE 1LMJA 2G00L 1V3XB 1TOZA 2J94B 1RFNB 3KQEL 2UWOB 3DEMA 1O5DL 5JVZA 1IQFL 2BZ6L 1KLOA 1KLIL 1EMOA 1COUA 3IJEB 1EPIA 4RUTA 2P16L 1XFEA 2Y5FL 1YGCL 4M10A 1G2MB 4CUFA 1ATEA
chains in the Genus database with same CATH superfamily
4RRYA 1NPEB 1IOXA 1W8BL 3M36L 2RNLA 4YT6L 4JZFL 2F9BL 1EPHA 5JB9E 3OLUA 1PFXL 3NJPC 3KQCL 1DQBA 1EPJA 1FJSL 1N1IA 4NGAL 3NT1A 1ADXA 3HPTA 1NZIA 1YUFA 2XC4L 4Z0LA 1U8CB 2VH6B 4ZXXL 2W2QE 3IITB 1IQLL 2P3FN 1JL9A 1YO8A 2P3UA 4XLWA 1HX2A 3LTFB 1G2LB 3F6UL 4X8TL 5L2YL 4JYVL 1G1TA 1YUKB 1XDTR 1YUGA 3HO5A 3HS5A 5L2ZL 2TGFA 5KIRA 1XKAL 3HO3A 1WU1B 2FLGA 5IKRA 3CENL 2K2TA 1UZQA 4BDWA 5IKQA 2FZZL 5IKTA 4AQTA 1IQJL 1DVAL 2PUQL 3K9XA 2Y81B 1FFMA 1LPZA 4OTYA 3ZYJB 1G1RA 2W2ME 3KL6B 1CVWL 2FLBL 2BT7A 3GCXE 2BOXA 1EQGA 4MMZB 2FD6A 2BQ6A 2J4IB 4Z6AL 2KL7A 2J2UB 2RA0L 1CCVA 1CQEA 2BQWA 2P94L 2DDUA 3C9AC 1KSNB 1IQML 3NTBA 1IP0A 3RR3A 1EBVA 3SOBB 1DX5I 2W86A 2P26A 4MMYB 1KIGL 3P5BL 1HT8A 3SW2A 3KQDL 4Y71B 1HCGB 1EQHA 4BXSA 2H9EL 2W2PE 2Y80B 2BOUA 1X7AL 4COXA 5CISA 1HREA 1IQNL 1EGFA 1IGXA 5F1AA 4GU4A 2W3IB 1ATBA 1U67A 3ZYIB 2PHBB 1IOEL 2WPKE 3M37L 1F0SB 2VJ3A 4O02B 2J34B 2EI6B 2VVVL 2W2OE 3N8YB 1IVOC 4Y7AB 4ISIL 2H9EC 5COXA 2KV4A 1DDXA 1MOXC 2WPIE 1UZKA 2WFXB 5E8DA 1EPGA 1HAEA 5EGMB 3HO4A 2HORA 4RRXA 1NQLB 5JVYA 2UWPB 1PGEA 2YGOA 4TGFA 4XBMA 1IQGL 2WG4B 1K37A 4G1MB 2WPLE 2JJLA 3ELAL 1CEJA 2W2NE 3TH3L 1W7XL 2WZPP 3F1SB 3S6XA 2Y5HL 4YT7L 2MGRA 2WYJB 3TBDA 2GD4A 3N8YA 1F7MA 4X8VL 3QMOA 3N8ZA 2Q1JB 4X8UL 3OLTA 1IQKL 2VVUL 1IQHL 2CJIB 4ISHL 2BQ7A 3LC5B 2KNIA 1BF9A 1TPGA 1HRFA 1L5GB 3Q3KB 2I9BA 2BOKL 2FLRL 3FFGL 3TZIA 3LAQA 4LORA 3EGFA 5CKNA 1FAKL 2BMGA 3BPSE 2EI7B 2NPRA 5JBBE 3TGFA 1OB1C 2EI8B 2J95B 4C16A 4NA9L 2BSFA 1CX2A 2WYGB 4CSYA 2VH0B 3TK5B 1P9JA 1JV2B 5IKVA 2Y7XB 4Y76B 4BTTA 3CFWA 1FSBA 1Q4GA 2OYUP 2Y7ZB 1EMNA 3LN0A 4JZEL 3H5CB 3MDLA 1IGZA 1HZ8A 3LIWB 5KN5C 4RRZA 3HS7A 2VWLL 4A94C 2XC5L 1NFUB 4JYUL 2RHPA 2WFTA 1M1XB 2XBXL 4YZUB 4JZDL 3N8XA 1V1IA 4D0FA 3ASIA 1LPKA 4PH9A 3TK6B 2B7DL 3CA7A 4E1GA 1UZPA 2P3TA 3V65B 2WPJE 5FDQA 4RS0A 1V1HA 2KB9A 4BDXA 1IQIL 5JB8E 1NFYB 2XBVL 1PTHA 1F0RB 1G1SA 3KQBL 3CS7L 4ZXYL 4Y79B 4O1ZA 1K36A 2J38B 3SOVA 3BT2A 1C5MF 4Y6DB 3GCWE 4OTJA 1IQEL 3KCGL 1EZQB 1URKA 2VWNL 4D0EA 2BT8A 5CKQA 1CCFA 1FF7A 3V64C 3SOQA 2P93L 4BTIA 1ATAA 3ZYGA 2HOXA 4GU3A 2WPME 2XBYL 1P0SL 2MHPA 2VWMK 4X8SL 4XL1A 1HT5A 3QCWA 2P95L 1TLEA 2PR3B 1F7EA 3ENSA 3N8VA 1DIYA 2P28B 1G1QA 4M11A 1MQ5L 2XBWL 1NFWB 4BXWA 2BOHA 1XKBA 3R05A 1AUTL 2Y82B 1PRHA 3LC3B 2Y38A 3Q7DA 3HS6A 4Z0KB 1I0UA 2XC0L 3KRKA 1FAXL 4ZH8B 2OYEP 1NFXB 3PGHA 1MQ6L 1IJQA 1SZBA 2WPHE 3FBYA 1L3YA 2WG3C 1APOA 2UWLB 4FM5A 1KKEA 2M74A 2BO2A 5CKMA 1A3PA 4Y7BB 1Z6EL 1CVUA 1JBUL 3NTGA 3GISX 4RRWA 1B9WA 1LPGA 2MGPA 1GK5A 4NG9L 5L30L 3U73A 1ATDA 3N8WB 1WHEA 2I9AA 2JKHL 2VWOL 5K0HB 4CUDA 3MQEA 2VRSA 5JBAE 1HAFA 2YGQA 4LMFA 2YGPA 4ZHAB 4MMXB 1QIUA 1HJ7A 2D1JB 2K2SB 6COXA 4D90A 3BT1A 1LQDA 2Y5GL 1FE2A 1QFKL 2ADXA 3FCSB 3QH0A 5F19A 5I46L 2VVCK 2AYLA 2W26B 1EAIC 4ZAEB 1UZJA 2P3FL 1LK9A 2W3KB 5JW1A 3U7UG 3LTGD 3POYA 1APQA 4BTUA 3LN1A 1NT0A 1ZAQA 1LMMA 1Z6CA 4CUEA 1J9CL 1KLJL 1PXXA 1N7DA 1WHFA 3N8WA 3KK6A 4A7IA 5JBCE 1LMJA 2G00L 1V3XB 1TOZA 2J94B 1RFNB 3KQEL 2UWOB 3DEMA 1O5DL 5JVZA 1IQFL 2BZ6L 1KLOA 1KLIL 1EMOA 1COUA 3IJEB 1EPIA 4RUTA 2P16L 1XFEA 2Y5FL 1YGCL 4M10A 1G2MB 4CUFA 1ATEA
chains in the Genus database with same CATH topology
4RRYA 1NPEB 1IOXA 1W8BL 3M36L 2RNLA 4YT6L 4JZFL 2F9BL 1EPHA 5JB9E 3OLUA 1PFXL 3NJPC 3KQCL 1DQBA 1EPJA 1FJSL 1N1IA 4NGAL 3NT1A 1ADXA 3HPTA 1NZIA 1YUFA 2XC4L 4Z0LA 1U8CB 2VH6B 4ZXXL 2W2QE 3IITB 1IQLL 2P3FN 1JL9A 1YO8A 2P3UA 4XLWA 1HX2A 3LTFB 1G2LB 3F6UL 4X8TL 5L2YL 4JYVL 1G1TA 1YUKB 1XDTR 1YUGA 3HO5A 3HS5A 5L2ZL 2TGFA 5KIRA 1XKAL 3HO3A 1WU1B 2FLGA 5IKRA 3CENL 2K2TA 1UZQA 4BDWA 5IKQA 2FZZL 5IKTA 4AQTA 1IQJL 1DVAL 2PUQL 3K9XA 2Y81B 1FFMA 1LPZA 4OTYA 3ZYJB 1G1RA 2W2ME 3KL6B 1CVWL 2FLBL 3GCXE 2BOXA 1EQGA 4MMZB 2FD6A 2BQ6A 2J4IB 4Z6AL 2KL7A 2J2UB 2RA0L 1CCVA 1CQEA 2BQWA 2P94L 2DDUA 3C9AC 1KSNB 1IQML 3NTBA 1IP0A 3RR3A 1EBVA 3SOBB 1DX5I 2W86A 2P26A 4MMYB 1KIGL 3P5BL 1HT8A 3SW2A 3KQDL 4Y71B 1HCGB 1EQHA 4BXSA 2H9EL 2W2PE 2Y80B 2BOUA 1X7AL 4COXA 5CISA 1HREA 1IQNL 1EGFA 1IGXA 5F1AA 2W3IB 1ATBA 1U67A 3ZYIB 2PHBB 1IOEL 2WPKE 3M37L 1F0SB 2VJ3A 4O02B 2J34B 2EI6B 2VVVL 2W2OE 3N8YB 1IVOC 4Y7AB 4ISIL 2H9EC 5COXA 2KV4A 1DDXA 1MOXC 2WPIE 1UZKA 2WFXB 5E8DA 1EPGA 1HAEA 5EGMB 3HO4A 4RRXA 1NQLB 5JVYA 2UWPB 1PGEA 2YGOA 4TGFA 4XBMA 1IQGL 2WG4B 1K37A 4G1MB 2WPLE 3ELAL 1CEJA 2W2NE 3TH3L 1W7XL 2WZPP 3F1SB 3S6XA 2Y5HL 4YT7L 2MGRA 2WYJB 3TBDA 2GD4A 3N8YA 1F7MA 4X8VL 3QMOA 3N8ZA 2Q1JB 4X8UL 3OLTA 1IQKL 2VVUL 1IQHL 2CJIB 4ISHL 2BQ7A 3LC5B 2KNIA 1BF9A 1TPGA 1HRFA 1L5GB 3Q3KB 2I9BA 2BOKL 2FLRL 3FFGL 3TZIA 3LAQA 4LORA 3EGFA 5CKNA 1FAKL 2BMGA 3BPSE 2EI7B 2NPRA 5JBBE 3TGFA 1OB1C 2EI8B 2J95B 4C16A 4NA9L 1CX2A 2WYGB 4CSYA 2VH0B 3TK5B 1P9JA 1JV2B 5IKVA 2Y7XB 4Y76B 4BTTA 3CFWA 1FSBA 1Q4GA 2OYUP 2Y7ZB 1EMNA 3LN0A 4JZEL 3H5CB 3MDLA 1IGZA 1HZ8A 3LIWB 5KN5C 4RRZA 3HS7A 2VWLL 4A94C 2XC5L 1NFUB 4JYUL 2RHPA 2WFTA 1M1XB 2XBXL 4YZUB 4JZDL 3N8XA 4D0FA 3ASIA 1LPKA 4PH9A 3TK6B 2B7DL 3CA7A 4E1GA 1UZPA 2P3TA 3V65B 2WPJE 5FDQA 4RS0A 2KB9A 4BDXA 1IQIL 5JB8E 1NFYB 2XBVL 1PTHA 1F0RB 1G1SA 3KQBL 3CS7L 4ZXYL 4Y79B 4O1ZA 1K36A 2J38B 3SOVA 3BT2A 1C5MF 4Y6DB 3GCWE 4OTJA 1IQEL 3KCGL 1EZQB 1URKA 2VWNL 4D0EA 5CKQA 1CCFA 1FF7A 3V64C 3SOQA 2P93L 4BTIA 1ATAA 3ZYGA 2WPME 2XBYL 1P0SL 2MHPA 2VWMK 4X8SL 4XL1A 1HT5A 3QCWA 2P95L 1TLEA 2PR3B 1F7EA 3ENSA 3N8VA 1DIYA 2P28B 1G1QA 4M11A 1MQ5L 2XBWL 1NFWB 4BXWA 2BOHA 1XKBA 3R05A 1AUTL 2Y82B 1PRHA 3LC3B 2Y38A 3Q7DA 3HS6A 4Z0KB 1I0UA 2XC0L 3KRKA 1FAXL 4ZH8B 2OYEP 1NFXB 3PGHA 1MQ6L 1IJQA 1SZBA 2WPHE 3FBYA 1L3YA 2WG3C 1APOA 2UWLB 4FM5A 2M74A 2BO2A 5CKMA 1A3PA 4Y7BB 1Z6EL 1CVUA 1JBUL 3NTGA 3GISX 4RRWA 1B9WA 1LPGA 2MGPA 1GK5A 4NG9L 5L30L 3U73A 1ATDA 3N8WB 1WHEA 2I9AA 2JKHL 2VWOL 5K0HB 4CUDA 3MQEA 5JBAE 1HAFA 2YGQA 4LMFA 2YGPA 4ZHAB 4MMXB 1HJ7A 2D1JB 2K2SB 6COXA 4D90A 3BT1A 1LQDA 2Y5GL 1FE2A 1QFKL 2ADXA 3FCSB 3QH0A 5F19A 5I46L 2VVCK 2AYLA 2W26B 1EAIC 4ZAEB 1UZJA 2P3FL 2W3KB 5JW1A 3U7UG 3LTGD 3POYA 1APQA 4BTUA 3LN1A 1NT0A 1ZAQA 1LMMA 1Z6CA 4CUEA 1J9CL 1KLJL 1PXXA 1N7DA 1WHFA 3N8WA 3KK6A 4A7IA 5JBCE 1LMJA 2G00L 1V3XB 1TOZA 2J94B 1RFNB 3KQEL 2UWOB 3DEMA 1O5DL 5JVZA 1IQFL 2BZ6L 1KLOA 1KLIL 1EMOA 1COUA 3IJEB 1EPIA 4RUTA 2P16L 1XFEA 2Y5FL 1YGCL 4M10A 1G2MB 4CUFA 1ATEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RRY A;  1NPE B;  1IOX A;  1W8B L;  3M36 L;  2RNL A;  4YT6 L;  4JZF L;  2F9B L;  1EPH A;  5JB9 E;  3OLU A;  1PFX L;  3NJP C;  3KQC L;  1DQB A;  1EPJ A;  1FJS L;  1N1I A;  4NGA L;  3NT1 A;  1ADX A;  3HPT A;  1NZI A;  1YUF A;  2XC4 L;  4Z0L A;  1U8C B;  2VH6 B;  4ZXX L;  2W2Q E;  3IIT B;  1IQL L;  2P3F N;  1JL9 A;  1YO8 A;  2P3U A;  4XLW A;  1HX2 A;  3LTF B;  1G2L B;  3F6U L;  4X8T L;  5L2Y L;  4JYV L;  1G1T A;  1YUK B;  1XDT R;  1YUG A;  3HO5 A;  3HS5 A;  5L2Z L;  2TGF A;  5KIR A;  1XKA L;  3HO3 A;  1WU1 B;  2FLG A;  5IKR A;  3CEN L;  2K2T A;  1UZQ A;  4BDW A;  5IKQ A;  2FZZ L;  5IKT A;  4AQT A;  1IQJ L;  1DVA L;  2PUQ L;  3K9X A;  2Y81 B;  1FFM A;  1LPZ A;  4OTY A;  3ZYJ B;  1G1R A;  2W2M E;  3KL6 B;  1CVW L;  2FLB L;  3GCX E;  2BOX A;  1EQG A;  4MMZ B;  2FD6 A;  2BQ6 A;  2J4I B;  4Z6A L;  2KL7 A;  2J2U B;  2RA0 L;  1CCV A;  1CQE A;  2BQW A;  2P94 L;  2DDU A;  3C9A C;  1KSN B;  1IQM L;  3NTB A;  1IP0 A;  3RR3 A;  1EBV A;  3SOB B;  1DX5 I;  2W86 A;  2P26 A;  4MMY B;  1KIG L;  3P5B L;  1HT8 A;  3SW2 A;  3KQD L;  4Y71 B;  1HCG B;  1EQH A;  4BXS A;  2H9E L;  2W2P E;  2Y80 B;  2BOU A;  1X7A L;  4COX A;  5CIS A;  1HRE A;  1IQN L;  1EGF A;  1IGX A;  5F1A A;  2W3I B;  1ATB A;  1U67 A;  3ZYI B;  2PHB B;  1IOE L;  2WPK E;  3M37 L;  1F0S B;  2VJ3 A;  4O02 B;  2J34 B;  2EI6 B;  2VVV L;  2W2O E;  3N8Y B;  1IVO C;  4Y7A B;  4ISI L;  5COX A;  2KV4 A;  1DDX A;  1MOX C;  2WPI E;  1UZK A;  2WFX B;  5E8D A;  1EPG A;  1HAE A;  5EGM B;  3HO4 A;  4RRX A;  1NQL B;  5JVY A;  2UWP B;  1PGE A;  2YGO A;  4TGF A;  4XBM A;  1IQG L;  2WG4 B;  1K37 A;  4G1M B;  2WPL E;  3ELA L;  1CEJ A;  2W2N E;  3TH3 L;  1W7X L;  3F1S B;  2Y5H L;  4YT7 L;  2MGR A;  2WYJ B;  3TBD A;  2GD4 A;  3N8Y A;  1F7M A;  4X8V L;  3QMO A;  3N8Z A;  2Q1J B;  4X8U L;  3OLT A;  1IQK L;  2VVU L;  1IQH L;  2CJI B;  4ISH L;  2BQ7 A;  3LC5 B;  1BF9 A;  1TPG A;  1HRF A;  1L5G B;  3Q3K B;  2I9B A;  2BOK L;  2FLR L;  3FFG L;  3TZI A;  3LAQ A;  4LOR A;  3EGF A;  5CKN A;  1FAK L;  2BMG A;  3BPS E;  2EI7 B;  2NPR A;  5JBB E;  3TGF A;  1OB1 C;  2EI8 B;  2J95 B;  4C16 A;  4NA9 L;  1CX2 A;  2WYG B;  4CSY A;  2VH0 B;  3TK5 B;  1P9J A;  1JV2 B;  5IKV A;  2Y7X B;  4Y76 B;  4BTT A;  3CFW A;  1FSB A;  1Q4G A;  2OYU P;  2Y7Z B;  1EMN A;  3LN0 A;  4JZE L;  3H5C B;  3MDL A;  1IGZ A;  1HZ8 A;  3LIW B;  5KN5 C;  4RRZ A;  3HS7 A;  2VWL L;  2XC5 L;  1NFU B;  4JYU L;  2RHP A;  2WFT A;  1M1X B;  2XBX L;  4YZU B;  4JZD L;  3N8X A;  4D0F A;  3ASI A;  1LPK A;  4PH9 A;  3TK6 B;  2B7D L;  3CA7 A;  4E1G A;  1UZP A;  2P3T A;  3V65 B;  2WPJ E;  5FDQ A;  4RS0 A;  2KB9 A;  4BDX A;  1IQI L;  5JB8 E;  1NFY B;  2XBV L;  1PTH A;  1F0R B;  1G1S A;  3KQB L;  3CS7 L;  4ZXY L;  4Y79 B;  4O1Z A;  1K36 A;  2J38 B;  3SOV A;  3BT2 A;  1C5M F;  4Y6D B;  3GCW E;  4OTJ A;  1IQE L;  3KCG L;  1EZQ B;  1URK A;  2VWN L;  4D0E A;  5CKQ A;  1CCF A;  1FF7 A;  3V64 C;  3SOQ A;  2P93 L;  4BTI A;  1ATA A;  3ZYG A;  2WPM E;  2XBY L;  1P0S L;  2MHP A;  2VWM K;  4X8S L;  4XL1 A;  1HT5 A;  3QCW A;  2P95 L;  1TLE A;  2PR3 B;  1F7E A;  3ENS A;  3N8V A;  1DIY A;  2P28 B;  1G1Q A;  4M11 A;  1MQ5 L;  2XBW L;  1NFW B;  4BXW A;  2BOH A;  1XKB A;  3R05 A;  1AUT L;  2Y82 B;  1PRH A;  3LC3 B;  2Y38 A;  3Q7D A;  3HS6 A;  4Z0K B;  1I0U A;  2XC0 L;  3KRK A;  1FAX L;  4ZH8 B;  2OYE P;  1NFX B;  3PGH A;  1MQ6 L;  1IJQ A;  1SZB A;  2WPH E;  3FBY A;  1L3Y A;  2WG3 C;  1APO A;  2UWL B;  4FM5 A;  2M74 A;  2BO2 A;  5CKM A;  1A3P A;  4Y7B B;  1Z6E L;  1CVU A;  1JBU L;  3NTG A;  3GIS X;  4RRW A;  1B9W A;  1LPG A;  2MGP A;  1GK5 A;  4NG9 L;  5L30 L;  3U73 A;  1ATD A;  3N8W B;  1WHE A;  2I9A A;  2JKH L;  2VWO L;  5K0H B;  4CUD A;  3MQE A;  5JBA E;  1HAF A;  4LMF A;  2YGP A;  4ZHA B;  4MMX B;  1HJ7 A;  2D1J B;  2K2S B;  6COX A;  4D90 A;  3BT1 A;  1LQD A;  2Y5G L;  1FE2 A;  1QFK L;  2ADX A;  3FCS B;  3QH0 A;  5F19 A;  5I46 L;  2VVC K;  2AYL A;  2W26 B;  1EAI C;  4ZAE B;  1UZJ A;  2P3F L;  2W3K B;  5JW1 A;  3U7U G;  3LTG D;  3POY A;  1APQ A;  4BTU A;  3LN1 A;  1NT0 A;  1ZAQ A;  1Z6C A;  4CUE A;  1J9C L;  1KLJ L;  1PXX A;  1N7D A;  1WHF A;  3N8W A;  3KK6 A;  4A7I A;  5JBC E;  1LMJ A;  2G00 L;  1V3X B;  1TOZ A;  2J94 B;  1RFN B;  3KQE L;  2UWO B;  3DEM A;  1O5D L;  5JVZ A;  1IQF L;  2BZ6 L;  1KLO A;  1KLI L;  1EMO A;  1COU A;  3IJE B;  1EPI A;  4RUT A;  2P16 L;  1XFE A;  2Y5F L;  1YGC L;  4M10 A;  1G2M B;  4CUF A;  1ATE A; 
#chains in the Genus database with same CATH topology
 4RRY A;  1NPE B;  1IOX A;  1W8B L;  3M36 L;  2RNL A;  4YT6 L;  4JZF L;  2F9B L;  1EPH A;  5JB9 E;  3OLU A;  1PFX L;  3NJP C;  3KQC L;  1DQB A;  1EPJ A;  1FJS L;  1N1I A;  4NGA L;  3NT1 A;  1ADX A;  3HPT A;  1NZI A;  1YUF A;  2XC4 L;  4Z0L A;  1U8C B;  2VH6 B;  4ZXX L;  2W2Q E;  3IIT B;  1IQL L;  2P3F N;  1JL9 A;  1YO8 A;  2P3U A;  4XLW A;  1HX2 A;  3LTF B;  1G2L B;  3F6U L;  4X8T L;  5L2Y L;  4JYV L;  1G1T A;  1YUK B;  1XDT R;  1YUG A;  3HO5 A;  3HS5 A;  5L2Z L;  2TGF A;  5KIR A;  1XKA L;  3HO3 A;  1WU1 B;  2FLG A;  5IKR A;  3CEN L;  2K2T A;  1UZQ A;  4BDW A;  5IKQ A;  2FZZ L;  5IKT A;  4AQT A;  1IQJ L;  1DVA L;  2PUQ L;  3K9X A;  2Y81 B;  1FFM A;  1LPZ A;  4OTY A;  3ZYJ B;  1G1R A;  2W2M E;  3KL6 B;  1CVW L;  2FLB L;  2BT7 A;  3GCX E;  2BOX A;  1EQG A;  4MMZ B;  2FD6 A;  2BQ6 A;  2J4I B;  4Z6A L;  2KL7 A;  2J2U B;  2RA0 L;  1CCV A;  1CQE A;  2BQW A;  2P94 L;  2DDU A;  3C9A C;  1KSN B;  1IQM L;  3NTB A;  1IP0 A;  3RR3 A;  1EBV A;  3SOB B;  1DX5 I;  2W86 A;  2P26 A;  4MMY B;  1KIG L;  3P5B L;  1HT8 A;  3SW2 A;  3KQD L;  4Y71 B;  1HCG B;  1EQH A;  4BXS A;  2H9E L;  2W2P E;  2Y80 B;  2BOU A;  1X7A L;  4COX A;  5CIS A;  1HRE A;  1IQN L;  1EGF A;  1IGX A;  5F1A A;  4GU4 A;  2W3I B;  1ATB A;  1U67 A;  3ZYI B;  2PHB B;  1IOE L;  2WPK E;  3M37 L;  1F0S B;  2VJ3 A;  4O02 B;  2J34 B;  2EI6 B;  2VVV L;  2W2O E;  3N8Y B;  1IVO C;  4Y7A B;  4ISI L;  2H9E C;  5COX A;  2KV4 A;  1DDX A;  1MOX C;  2WPI E;  1UZK A;  2WFX B;  5E8D A;  1EPG A;  1HAE A;  5EGM B;  3HO4 A;  2HOR A;  4RRX A;  1NQL B;  5JVY A;  2UWP B;  1PGE A;  2YGO A;  4TGF A;  4XBM A;  1IQG L;  2WG4 B;  1K37 A;  4G1M B;  2WPL E;  2JJL A;  3ELA L;  1CEJ A;  2W2N E;  3TH3 L;  1W7X L;  2WZP P;  3F1S B;  3S6X A;  2Y5H L;  4YT7 L;  2MGR A;  2WYJ B;  3TBD A;  2GD4 A;  3N8Y A;  1F7M A;  4X8V L;  3QMO A;  3N8Z A;  2Q1J B;  4X8U L;  3OLT A;  1IQK L;  2VVU L;  1IQH L;  2CJI B;  4ISH L;  2BQ7 A;  3LC5 B;  2KNI A;  1BF9 A;  1TPG A;  1HRF A;  1L5G B;  3Q3K B;  2I9B A;  2BOK L;  2FLR L;  3FFG L;  3TZI A;  3LAQ A;  4LOR A;  3EGF A;  5CKN A;  1FAK L;  2BMG A;  3BPS E;  2EI7 B;  2NPR A;  5JBB E;  3TGF A;  1OB1 C;  2EI8 B;  2J95 B;  4C16 A;  4NA9 L;  2BSF A;  1CX2 A;  2WYG B;  4CSY A;  2VH0 B;  3TK5 B;  1P9J A;  1JV2 B;  5IKV A;  2Y7X B;  4Y76 B;  4BTT A;  3CFW A;  1FSB A;  1Q4G A;  2OYU P;  2Y7Z B;  1EMN A;  3LN0 A;  4JZE L;  3H5C B;  3MDL A;  1IGZ A;  1HZ8 A;  3LIW B;  5KN5 C;  4RRZ A;  3HS7 A;  2VWL L;  4A94 C;  2XC5 L;  1NFU B;  4JYU L;  2RHP A;  2WFT A;  1M1X B;  2XBX L;  4YZU B;  4JZD L;  3N8X A;  1V1I A;  4D0F A;  3ASI A;  1LPK A;  4PH9 A;  3TK6 B;  2B7D L;  3CA7 A;  4E1G A;  1UZP A;  2P3T A;  3V65 B;  2WPJ E;  5FDQ A;  4RS0 A;  1V1H A;  2KB9 A;  4BDX A;  1IQI L;  5JB8 E;  1NFY B;  2XBV L;  1PTH A;  1F0R B;  1G1S A;  3KQB L;  3CS7 L;  4ZXY L;  4Y79 B;  4O1Z A;  1K36 A;  2J38 B;  3SOV A;  3BT2 A;  1C5M F;  4Y6D B;  3GCW E;  4OTJ A;  1IQE L;  3KCG L;  1EZQ B;  1URK A;  2VWN L;  4D0E A;  2BT8 A;  5CKQ A;  1CCF A;  1FF7 A;  3V64 C;  3SOQ A;  2P93 L;  4BTI A;  1ATA A;  3ZYG A;  2HOX A;  4GU3 A;  2WPM E;  2XBY L;  1P0S L;  2MHP A;  2VWM K;  4X8S L;  4XL1 A;  1HT5 A;  3QCW A;  2P95 L;  1TLE A;  2PR3 B;  1F7E A;  3ENS A;  3N8V A;  1DIY A;  2P28 B;  1G1Q A;  4M11 A;  1MQ5 L;  2XBW L;  1NFW B;  4BXW A;  2BOH A;  1XKB A;  3R05 A;  1AUT L;  2Y82 B;  1PRH A;  3LC3 B;  2Y38 A;  3Q7D A;  3HS6 A;  4Z0K B;  1I0U A;  2XC0 L;  3KRK A;  1FAX L;  4ZH8 B;  2OYE P;  1NFX B;  3PGH A;  1MQ6 L;  1IJQ A;  1SZB A;  2WPH E;  3FBY A;  1L3Y A;  2WG3 C;  1APO A;  2UWL B;  4FM5 A;  1KKE A;  2M74 A;  2BO2 A;  5CKM A;  1A3P A;  4Y7B B;  1Z6E L;  1CVU A;  1JBU L;  3NTG A;  3GIS X;  4RRW A;  1B9W A;  1LPG A;  2MGP A;  1GK5 A;  4NG9 L;  5L30 L;  3U73 A;  1ATD A;  3N8W B;  1WHE A;  2I9A A;  2JKH L;  2VWO L;  5K0H B;  4CUD A;  3MQE A;  2VRS A;  5JBA E;  1HAF A;  2YGQ A;  4LMF A;  2YGP A;  4ZHA B;  4MMX B;  1QIU A;  1HJ7 A;  2D1J B;  2K2S B;  6COX A;  4D90 A;  3BT1 A;  1LQD A;  2Y5G L;  1FE2 A;  1QFK L;  2ADX A;  3FCS B;  3QH0 A;  5F19 A;  5I46 L;  2VVC K;  2AYL A;  2W26 B;  1EAI C;  4ZAE B;  1UZJ A;  2P3F L;  1LK9 A;  2W3K B;  5JW1 A;  3U7U G;  3LTG D;  3POY A;  1APQ A;  4BTU A;  3LN1 A;  1NT0 A;  1ZAQ A;  1LMM A;  1Z6C A;  4CUE A;  1J9C L;  1KLJ L;  1PXX A;  1N7D A;  1WHF A;  3N8W A;  3KK6 A;  4A7I A;  5JBC E;  1LMJ A;  2G00 L;  1V3X B;  1TOZ A;  2J94 B;  1RFN B;  3KQE L;  2UWO B;  3DEM A;  1O5D L;  5JVZ A;  1IQF L;  2BZ6 L;  1KLO A;  1KLI L;  1EMO A;  1COU A;  3IJE B;  1EPI A;  4RUT A;  2P16 L;  1XFE A;  2Y5F L;  1YGC L;  4M10 A;  1G2M B;  4CUF A;  1ATE A; 
#chains in the Genus database with same CATH homology
 4RRY A;  1NPE B;  1IOX A;  1W8B L;  3M36 L;  2RNL A;  4YT6 L;  4JZF L;  2F9B L;  1EPH A;  5JB9 E;  3OLU A;  1PFX L;  3NJP C;  3KQC L;  1DQB A;  1EPJ A;  1FJS L;  1N1I A;  4NGA L;  3NT1 A;  1ADX A;  3HPT A;  1NZI A;  1YUF A;  2XC4 L;  4Z0L A;  1U8C B;  2VH6 B;  4ZXX L;  2W2Q E;  3IIT B;  1IQL L;  2P3F N;  1JL9 A;  1YO8 A;  2P3U A;  4XLW A;  1HX2 A;  3LTF B;  1G2L B;  3F6U L;  4X8T L;  5L2Y L;  4JYV L;  1G1T A;  1YUK B;  1XDT R;  1YUG A;  3HO5 A;  3HS5 A;  5L2Z L;  2TGF A;  5KIR A;  1XKA L;  3HO3 A;  1WU1 B;  2FLG A;  5IKR A;  3CEN L;  2K2T A;  1UZQ A;  4BDW A;  5IKQ A;  2FZZ L;  5IKT A;  4AQT A;  1IQJ L;  1DVA L;  2PUQ L;  3K9X A;  2Y81 B;  1FFM A;  1LPZ A;  4OTY A;  3ZYJ B;  1G1R A;  2W2M E;  3KL6 B;  1CVW L;  2FLB L;  3GCX E;  2BOX A;  1EQG A;  4MMZ B;  2FD6 A;  2BQ6 A;  2J4I B;  4Z6A L;  2KL7 A;  2J2U B;  2RA0 L;  1CCV A;  1CQE A;  2BQW A;  2P94 L;  2DDU A;  3C9A C;  1KSN B;  1IQM L;  3NTB A;  1IP0 A;  3RR3 A;  1EBV A;  3SOB B;  1DX5 I;  2W86 A;  2P26 A;  4MMY B;  1KIG L;  3P5B L;  1HT8 A;  3SW2 A;  3KQD L;  4Y71 B;  1HCG B;  1EQH A;  4BXS A;  2H9E L;  2W2P E;  2Y80 B;  2BOU A;  1X7A L;  4COX A;  5CIS A;  1HRE A;  1IQN L;  1EGF A;  1IGX A;  5F1A A;  2W3I B;  1ATB A;  1U67 A;  3ZYI B;  2PHB B;  1IOE L;  2WPK E;  3M37 L;  1F0S B;  2VJ3 A;  4O02 B;  2J34 B;  2EI6 B;  2VVV L;  2W2O E;  3N8Y B;  1IVO C;  4Y7A B;  4ISI L;  2H9E C;  5COX A;  2KV4 A;  1DDX A;  1MOX C;  2WPI E;  1UZK A;  2WFX B;  5E8D A;  1EPG A;  1HAE A;  5EGM B;  3HO4 A;  4RRX A;  1NQL B;  5JVY A;  2UWP B;  1PGE A;  2YGO A;  4TGF A;  4XBM A;  1IQG L;  2WG4 B;  1K37 A;  4G1M B;  2WPL E;  3ELA L;  1CEJ A;  2W2N E;  3TH3 L;  1W7X L;  2WZP P;  3F1S B;  3S6X A;  2Y5H L;  4YT7 L;  2MGR A;  2WYJ B;  3TBD A;  2GD4 A;  3N8Y A;  1F7M A;  4X8V L;  3QMO A;  3N8Z A;  2Q1J B;  4X8U L;  3OLT A;  1IQK L;  2VVU L;  1IQH L;  2CJI B;  4ISH L;  2BQ7 A;  3LC5 B;  2KNI A;  1BF9 A;  1TPG A;  1HRF A;  1L5G B;  3Q3K B;  2I9B A;  2BOK L;  2FLR L;  3FFG L;  3TZI A;  3LAQ A;  4LOR A;  3EGF A;  5CKN A;  1FAK L;  2BMG A;  3BPS E;  2EI7 B;  2NPR A;  5JBB E;  3TGF A;  1OB1 C;  2EI8 B;  2J95 B;  4C16 A;  4NA9 L;  1CX2 A;  2WYG B;  4CSY A;  2VH0 B;  3TK5 B;  1P9J A;  1JV2 B;  5IKV A;  2Y7X B;  4Y76 B;  4BTT A;  3CFW A;  1FSB A;  1Q4G A;  2OYU P;  2Y7Z B;  1EMN A;  3LN0 A;  4JZE L;  3H5C B;  3MDL A;  1IGZ A;  1HZ8 A;  3LIW B;  5KN5 C;  4RRZ A;  3HS7 A;  2VWL L;  4A94 C;  2XC5 L;  1NFU B;  4JYU L;  2RHP A;  2WFT A;  1M1X B;  2XBX L;  4YZU B;  4JZD L;  3N8X A;  4D0F A;  3ASI A;  1LPK A;  4PH9 A;  3TK6 B;  2B7D L;  3CA7 A;  4E1G A;  1UZP A;  2P3T A;  3V65 B;  2WPJ E;  5FDQ A;  4RS0 A;  2KB9 A;  4BDX A;  1IQI L;  5JB8 E;  1NFY B;  2XBV L;  1PTH A;  1F0R B;  1G1S A;  3KQB L;  3CS7 L;  4ZXY L;  4Y79 B;  4O1Z A;  1K36 A;  2J38 B;  3SOV A;  3BT2 A;  1C5M F;  4Y6D B;  3GCW E;  4OTJ A;  1IQE L;  3KCG L;  1EZQ B;  1URK A;  2VWN L;  4D0E A;  5CKQ A;  1CCF A;  1FF7 A;  3V64 C;  3SOQ A;  2P93 L;  4BTI A;  1ATA A;  3ZYG A;  2WPM E;  2XBY L;  1P0S L;  2MHP A;  2VWM K;  4X8S L;  4XL1 A;  1HT5 A;  3QCW A;  2P95 L;  1TLE A;  2PR3 B;  1F7E A;  3ENS A;  3N8V A;  1DIY A;  2P28 B;  1G1Q A;  4M11 A;  1MQ5 L;  2XBW L;  1NFW B;  4BXW A;  2BOH A;  1XKB A;  3R05 A;  1AUT L;  2Y82 B;  1PRH A;  3LC3 B;  2Y38 A;  3Q7D A;  3HS6 A;  4Z0K B;  1I0U A;  2XC0 L;  3KRK A;  1FAX L;  4ZH8 B;  2OYE P;  1NFX B;  3PGH A;  1MQ6 L;  1IJQ A;  1SZB A;  2WPH E;  3FBY A;  1L3Y A;  2WG3 C;  1APO A;  2UWL B;  4FM5 A;  2M74 A;  2BO2 A;  5CKM A;  1A3P A;  4Y7B B;  1Z6E L;  1CVU A;  1JBU L;  3NTG A;  3GIS X;  4RRW A;  1B9W A;  1LPG A;  2MGP A;  1GK5 A;  4NG9 L;  5L30 L;  3U73 A;  1ATD A;  3N8W B;  1WHE A;  2I9A A;  2JKH L;  2VWO L;  5K0H B;  4CUD A;  3MQE A;  5JBA E;  1HAF A;  2YGQ A;  4LMF A;  2YGP A;  4ZHA B;  4MMX B;  1HJ7 A;  2D1J B;  2K2S B;  6COX A;  4D90 A;  3BT1 A;  1LQD A;  2Y5G L;  1FE2 A;  1QFK L;  2ADX A;  3FCS B;  3QH0 A;  5F19 A;  5I46 L;  2VVC K;  2AYL A;  2W26 B;  1EAI C;  4ZAE B;  1UZJ A;  2P3F L;  2W3K B;  5JW1 A;  3U7U G;  3LTG D;  3POY A;  1APQ A;  4BTU A;  3LN1 A;  1NT0 A;  1ZAQ A;  1LMM A;  1Z6C A;  4CUE A;  1J9C L;  1KLJ L;  1PXX A;  1N7D A;  1WHF A;  3N8W A;  3KK6 A;  4A7I A;  5JBC E;  1LMJ A;  2G00 L;  1V3X B;  1TOZ A;  2J94 B;  1RFN B;  3KQE L;  2UWO B;  3DEM A;  1O5D L;  5JVZ A;  1IQF L;  2BZ6 L;  1KLO A;  1KLI L;  1EMO A;  1COU A;  3IJE B;  1EPI A;  4RUT A;  2P16 L;  1XFE A;  2Y5F L;  1YGC L;  4M10 A;  1G2M B;  4CUF A;  1ATE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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