1LPKA

Crystal structure of fxa in complex with 125.
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
53
structure length
53
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and Quantitative Structure-Activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Blood coagulation factor Xa
total genus 12
structure length 53
sequence length 53
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2002-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00008 EGF EGF-like domain
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1lpkA00
3OLUA 1IQJL 2Y38A 3TK5B 2WFTA 1DIYA 4RRXA 3QH0A 2Y5GL 1UZKA 1YUKB 4NG9L 2BOXA 1SZBA 1JV2B 3N8YA 5KN5C 3BPSE 1HCGB 1X7AL 3LTGD 1HT8A 2BZ6L 4NGAL 1F7MA 2WPIE 1XKAL 1IOEL 2TGFA 2XC4L 2FLRL 3QMOA 1URKA 3LN0A 5L2YL 3IJEB 1YUGA 3KCGL 1JBUL 1LPZA 1WHFA 1IP0A 3QCWA 1WHEA 3N8ZA 2UWOB 4X8VL 3PGHA 2P3FL 1IQGL 3HPTA 1FAXL 2J4IB 5F19A 3LC5B 3R05A 4BDWA 1EPJA 2WFXB 2W2NE 2YGPA 1NQLB 1P0SL 3SOBB 1U67A 2MGRA 4ZXYL 2PR3B 4CUEA 3V64C 2B7DL 3KL6B 1K36A 1FJSL 5IKTA 4YT6L 2BMGA 2UWPB 3N8VA 4C16A 3LC3B 4OTYA 2WPJE 5EGMB 2J38B 2Y7XB 4G1MB 3ZYJB 4D90A 1DDXA 4RS0A 4Z0KB 3LTFB 1G2MB 1YUFA 3GCWE 4M11A 2MHPA 3ZYGA 3TGFA 2WG3C 2XBWL 3TBDA 3HO3A 1YGCL 1FAKL 1IQEL 1V3XB 3ASIA 2W2ME 3H5CB 5IKQA 5I46L 4NA9L 1EQGA 3C9AC 2D1JB 6COXA 1KSNB 2NPRA 3TK6B 1APQA 1UZJA 3N8XA 1B9WA 2Y5FL 2BO2A 2VVCK 1N7DA 1G1QA 1G1RA 2Y80B 1IQKL 2XC0L 2XBVL 1RFNB 1EMOA 3NTBA 2FLGA 3NJPC 2VWNL 1JL9A 1EMNA 4Z6AL 1IJQA 1ATEA 1EGFA 2EI7B 2P16L 4RRWA 2PUQL 1UZQA 5JW1A 2BOUA 4BTTA 1G1TA 1Z6CA 2VWLL 2W2QE 5CKNA 1IOXA 3MDLA 5CKMA 1IQHL 4JYVL 4TGFA 1EZQB 5FDQA 4JZEL 4D0EA 2MGPA 5IKVA 5K0HB 2RA0L 2G00L 3U73A 2K2SB 4Y71B 1MQ5L 2UWLB 1O5DL 2JKHL 1KIGL 1W7XL 1PXXA 2K2TA 3HS6A 2W3KB 3HO4A 5CKQA 2WPLE 2WPME 4BTUA 4XLWA 4Z0LA 2AYLA 3FFGL 4X8TL 1IQNL 2FLBL 2RHPA 2WG4B 1L3YA 1F7EA 2VWOL 3EGFA 4E1GA 1N1IA 1YO8A 1UZPA 3FBYA 4X8UL 1EQHA 1TOZA 3TZIA 1Z6EL 2W26B 1TLEA 4BDXA 1GK5A 4O1ZA 1PGEA 2FZZL 1CVWL 2J94B 3Q3KB 2WYJB 5JB8E 4XBMA 3DEMA 4X8SL 1FF7A 3OLTA 4RRYA 1LPGA 2J95B 3KQDL 1A3PA 2EI8B 4BXSA 2OYUP 3LIWB 2KB9A 4CUDA 4Y76B 4PH9A 1Q4GA 1IQIL 2WPKE 1PTHA 2P93L 3HS5A 2P28B 4M10A 2ADXA 1LPKA 5KIRA 3ENSA 1CQEA 1W8BL 3CS7L 1M1XB 3N8WA 4MMXB 2P95L 1PFXL 2YGOA 2M74A 3F1SB 1KLJL 1BF9A 2KV4A 2WPHE 3F6UL 3KRKA 4CSYA 2BOKL 1NFYB 4MMZB 4LMFA 4COXA 1CCVA 1HREA 2W2PE 1NT0A 4YT7L 2P94L 1HX2A 2BQ7A 2EI6B 4Y79B 1OB1C 2W86A 3K9XA 5IKRA 2BQ6A 3POYA 1EPHA 2CJIB 4JZDL 4ZH8B 1ZAQA 1PRHA 2H9EL 3N8WB 1LQDA 3U7UG 1IGZA 2OYEP 4ZAEB 4XL1A 1HT5A 1FSBA 2VVVL 3ZYIB 5F1AA 1K37A 2P26A 2F9BL 3BT2A 2Y7ZB 2J34B 2I9BA 1J9CL 3SOVA 5L2ZL 3CFWA 1HZ8A 3FCSB 2I9AA 2BQWA 1FFMA 3LN1A 4RUTA 2Y5HL 4Y7BB 4ISIL 1COUA 1DVAL 1P9JA 3NTGA 4ZXXL 1LMJA 2P3FN 5E8DA 3MQEA 1C5MF 5JBAE 1IVOC 1IQFL 2W2OE 1TPGA 2Y82B 2WYGB 1DQBA 3TH3L 4OTJA 3KQBL 3KQCL 4RRZA 4BXWA 3KK6A 5JVYA 3HO5A 2VVUL 3SOQA 1I0UA 4O02B 1EPGA 1ADXA 1KLIL 3N8YB 1HRFA 5L30L 4MMYB 1XFEA 4ISHL 1EAIC 1NFWB 3Q7DA 5JBCE 1AUTL 1WU1B 5JVZA 4FM5A 1HJ7A 4JYUL 2P3UA 2VJ3A 1KLOA 2XBYL 2XC5L 2XBXL 1CEJA 1IQML 1CCFA 4YZUB 4A7IA 4Y6DB 1NFUB 1MQ6L 2RNLA 4CUFA 1XDTR 2W3IB 1FE2A 2BOHA 2VH6B 3CENL 3M36L 1ATBA 3ELAL 1MOXC 3NT1A 2Q1JB 1DX5I 1G2LB 4Y7AB 4ZHAB 5JB9E 1QFKL 3LAQA 2J2UB 2VWMK 3P5BL 5COXA 1HAFA 1NZIA 4JZFL 1IGXA 2PHBB 5JBBE 1F0SB 1CX2A 3CA7A 2GD4A 2Y81B 1CVUA 2KL7A 2DDUA 3BT1A 4LORA 5CISA 1L5GB 3RR3A 1F0RB 1NFXB 3KQEL 3GCXE 1EPIA 1EBVA 3GISX 1U8CB 4D0FA 1ATDA 1IQLL 2P3TA 1XKBA 3HS7A 3M37L 4AQTA 4BTIA 1HAEA 1NPEB 1ATAA 2VH0B 1APOA 1G1SA 3SW2A 3IITB 2FD6A 3V65B
chains in the Genus database with same CATH superfamily
3OLUA 1IQJL 2Y38A 3TK5B 2WFTA 1DIYA 4RRXA 3QH0A 2Y5GL 1UZKA 1YUKB 4NG9L 2BOXA 1SZBA 1JV2B 3N8YA 5KN5C 3BPSE 1HCGB 1X7AL 3LTGD 1HT8A 2BZ6L 4NGAL 1F7MA 4GU3A 2WPIE 1XKAL 1IOEL 2TGFA 2XC4L 2FLRL 3QMOA 1URKA 3LN0A 5L2YL 3IJEB 1YUGA 3KCGL 1JBUL 2H9EC 1LPZA 1WHFA 1IP0A 3QCWA 1WHEA 3N8ZA 2UWOB 4X8VL 3PGHA 2P3FL 1IQGL 3HPTA 1FAXL 2J4IB 5F19A 3LC5B 3R05A 4BDWA 1EPJA 2WFXB 2W2NE 2YGPA 1NQLB 1P0SL 3SOBB 1U67A 2MGRA 4ZXYL 2PR3B 1KKEA 4CUEA 3V64C 2B7DL 3KL6B 1K36A 1FJSL 5IKTA 4YT6L 2BMGA 2UWPB 1V1IA 3N8VA 4C16A 3LC3B 4OTYA 2WPJE 5EGMB 2J38B 2Y7XB 4G1MB 3ZYJB 4D90A 1DDXA 4RS0A 4Z0KB 3LTFB 1G2MB 1YUFA 3GCWE 4M11A 2MHPA 3ZYGA 3TGFA 2WG3C 2XBWL 2YGQA 3TBDA 3HO3A 1YGCL 1FAKL 1IQEL 1V3XB 3ASIA 2W2ME 3H5CB 5IKQA 5I46L 4NA9L 1EQGA 3C9AC 2D1JB 6COXA 2KNIA 1KSNB 2NPRA 3TK6B 1APQA 1UZJA 1LK9A 3N8XA 1B9WA 2Y5FL 2BO2A 2VVCK 1N7DA 1G1QA 1G1RA 2Y80B 1IQKL 2XC0L 2JJLA 2XBVL 1RFNB 1EMOA 3NTBA 2FLGA 3NJPC 2VWNL 1JL9A 1EMNA 4Z6AL 1IJQA 1ATEA 1EGFA 2EI7B 2P16L 4RRWA 2PUQL 1UZQA 5JW1A 2BOUA 4BTTA 1G1TA 1Z6CA 2VWLL 2W2QE 5CKNA 1IOXA 3MDLA 5CKMA 1IQHL 4JYVL 4TGFA 1EZQB 5FDQA 4JZEL 4D0EA 2MGPA 5IKVA 5K0HB 2RA0L 2G00L 3U73A 2K2SB 4Y71B 1MQ5L 2UWLB 1O5DL 2JKHL 1KIGL 1W7XL 1PXXA 2K2TA 3HS6A 2W3KB 3HO4A 5CKQA 2WPLE 2WPME 4BTUA 4XLWA 4Z0LA 2AYLA 3FFGL 4X8TL 1IQNL 2FLBL 2RHPA 2WG4B 1L3YA 1F7EA 2BT8A 2VWOL 3EGFA 4E1GA 1N1IA 1YO8A 1UZPA 3FBYA 4X8UL 1EQHA 1TOZA 3TZIA 1Z6EL 2W26B 1TLEA 4BDXA 1GK5A 4O1ZA 1PGEA 2WZPP 2FZZL 1CVWL 2J94B 3Q3KB 2WYJB 5JB8E 4XBMA 3DEMA 4X8SL 1FF7A 3OLTA 4RRYA 1LPGA 2J95B 3KQDL 1A3PA 2EI8B 4BXSA 2OYUP 3LIWB 2KB9A 4CUDA 4Y76B 4PH9A 1Q4GA 1IQIL 2WPKE 1PTHA 2P93L 3HS5A 2P28B 4M10A 2ADXA 1LPKA 5KIRA 3ENSA 1CQEA 1W8BL 2BT7A 2VRSA 1M1XB 3CS7L 3N8WA 4MMXB 2P95L 1PFXL 2YGOA 2M74A 3F1SB 1KLJL 1BF9A 2KV4A 2WPHE 3F6UL 3KRKA 4CSYA 2BOKL 1NFYB 4MMZB 4LMFA 4COXA 1CCVA 1HREA 2W2PE 1NT0A 4YT7L 2P94L 1HX2A 2BQ7A 2EI6B 4Y79B 1OB1C 2W86A 3K9XA 5IKRA 2BQ6A 3POYA 1EPHA 2CJIB 4JZDL 4ZH8B 1QIUA 1ZAQA 1PRHA 2H9EL 4GU4A 2HORA 3N8WB 1LQDA 3U7UG 1IGZA 2OYEP 4ZAEB 4XL1A 1HT5A 1FSBA 2VVVL 3ZYIB 5F1AA 1K37A 2P26A 2F9BL 3BT2A 2Y7ZB 2J34B 2I9BA 1J9CL 3SOVA 5L2ZL 3CFWA 1HZ8A 3FCSB 2I9AA 2BQWA 1FFMA 3LN1A 4RUTA 2Y5HL 4Y7BB 4ISIL 1COUA 1DVAL 1P9JA 3NTGA 4ZXXL 1LMJA 2P3FN 5E8DA 3MQEA 1C5MF 5JBAE 1IVOC 1IQFL 2W2OE 1TPGA 2Y82B 2WYGB 1DQBA 3TH3L 4OTJA 3KQBL 3KQCL 4RRZA 4BXWA 3KK6A 5JVYA 3HO5A 2VVUL 3SOQA 1I0UA 4O02B 1EPGA 1LMMA 1ADXA 1KLIL 3N8YB 1HRFA 5L30L 4MMYB 1XFEA 4ISHL 1EAIC 1NFWB 3Q7DA 5JBCE 1AUTL 1WU1B 5JVZA 4FM5A 1HJ7A 4JYUL 2P3UA 2VJ3A 1KLOA 2XBYL 2XC5L 2XBXL 1CEJA 1IQML 1CCFA 4YZUB 4A7IA 4Y6DB 1NFUB 1MQ6L 2RNLA 4CUFA 1XDTR 2W3IB 1FE2A 2BOHA 2VH6B 3CENL 3M36L 1V1HA 1ATBA 3ELAL 1MOXC 3NT1A 2Q1JB 1DX5I 1G2LB 4Y7AB 4ZHAB 5JB9E 1QFKL 3LAQA 2J2UB 2VWMK 3P5BL 5COXA 1HAFA 1NZIA 4JZFL 2HOXA 1IGXA 2PHBB 5JBBE 1F0SB 1CX2A 3CA7A 2GD4A 2Y81B 1CVUA 2KL7A 2DDUA 3BT1A 4LORA 5CISA 1L5GB 3S6XA 3RR3A 1F0RB 1NFXB 3KQEL 3GCXE 1EPIA 1EBVA 3GISX 1U8CB 4D0FA 1ATDA 1IQLL 2P3TA 1XKBA 3HS7A 3M37L 4AQTA 4BTIA 1HAEA 2BSFA 1NPEB 1ATAA 2VH0B 1APOA 1G1SA 3SW2A 3IITB 4A94C 2FD6A 3V65B
chains in the Genus database with same CATH topology
3OLUA 1IQJL 2Y38A 3TK5B 2WFTA 1DIYA 4RRXA 3QH0A 2Y5GL 1UZKA 1YUKB 4NG9L 2BOXA 1SZBA 1JV2B 3N8YA 5KN5C 3BPSE 1HCGB 1X7AL 3LTGD 1HT8A 2BZ6L 4NGAL 1F7MA 2WPIE 1XKAL 1IOEL 2TGFA 2XC4L 2FLRL 3QMOA 1URKA 3LN0A 5L2YL 3IJEB 1YUGA 3KCGL 1JBUL 2H9EC 1LPZA 1WHFA 1IP0A 3QCWA 1WHEA 3N8ZA 2UWOB 4X8VL 3PGHA 2P3FL 1IQGL 3HPTA 1FAXL 2J4IB 5F19A 3LC5B 3R05A 4BDWA 1EPJA 2WFXB 2W2NE 2YGPA 1NQLB 1P0SL 3SOBB 1U67A 2MGRA 4ZXYL 2PR3B 4CUEA 3V64C 2B7DL 3KL6B 1K36A 1FJSL 5IKTA 4YT6L 2BMGA 2UWPB 3N8VA 4C16A 3LC3B 4OTYA 2WPJE 5EGMB 2J38B 2Y7XB 4G1MB 3ZYJB 4D90A 1DDXA 4RS0A 4Z0KB 3LTFB 1G2MB 1YUFA 3GCWE 4M11A 2MHPA 3ZYGA 3TGFA 2WG3C 2XBWL 2YGQA 3TBDA 3HO3A 1YGCL 1FAKL 1IQEL 1V3XB 3ASIA 2W2ME 3H5CB 5IKQA 5I46L 4NA9L 1EQGA 3C9AC 2D1JB 6COXA 2KNIA 1KSNB 2NPRA 3TK6B 1APQA 1UZJA 3N8XA 1B9WA 2Y5FL 2BO2A 2VVCK 1N7DA 1G1QA 1G1RA 2Y80B 1IQKL 2XC0L 2XBVL 1RFNB 1EMOA 3NTBA 2FLGA 3NJPC 2VWNL 1JL9A 1EMNA 4Z6AL 1IJQA 1ATEA 1EGFA 2EI7B 2P16L 4RRWA 2PUQL 1UZQA 5JW1A 2BOUA 4BTTA 1G1TA 1Z6CA 2VWLL 2W2QE 5CKNA 1IOXA 3MDLA 5CKMA 1IQHL 4JYVL 4TGFA 1EZQB 5FDQA 4JZEL 4D0EA 2MGPA 5IKVA 5K0HB 2RA0L 2G00L 3U73A 2K2SB 4Y71B 1MQ5L 2UWLB 1O5DL 2JKHL 1KIGL 1W7XL 1PXXA 2K2TA 3HS6A 2W3KB 3HO4A 5CKQA 2WPLE 2WPME 4BTUA 4XLWA 4Z0LA 2AYLA 3FFGL 4X8TL 1IQNL 2FLBL 2RHPA 2WG4B 1L3YA 1F7EA 2VWOL 3EGFA 4E1GA 1N1IA 1YO8A 1UZPA 3FBYA 4X8UL 1EQHA 1TOZA 3TZIA 1Z6EL 2W26B 1TLEA 4BDXA 1GK5A 4O1ZA 1PGEA 2WZPP 2FZZL 1CVWL 2J94B 3Q3KB 2WYJB 5JB8E 4XBMA 3DEMA 4X8SL 1FF7A 3OLTA 4RRYA 1LPGA 2J95B 3KQDL 1A3PA 2EI8B 4BXSA 2OYUP 3LIWB 2KB9A 4CUDA 4Y76B 4PH9A 1Q4GA 1IQIL 2WPKE 1PTHA 2P93L 3HS5A 2P28B 4M10A 2ADXA 1LPKA 5KIRA 3ENSA 1CQEA 1W8BL 3CS7L 1M1XB 3N8WA 4MMXB 2P95L 1PFXL 2YGOA 2M74A 3F1SB 1KLJL 1BF9A 2KV4A 2WPHE 3F6UL 3KRKA 4CSYA 2BOKL 1NFYB 4MMZB 4LMFA 4COXA 1CCVA 1HREA 2W2PE 1NT0A 4YT7L 2P94L 1HX2A 2BQ7A 2EI6B 4Y79B 1OB1C 2W86A 3K9XA 5IKRA 2BQ6A 3POYA 1EPHA 2CJIB 4JZDL 4ZH8B 1ZAQA 1PRHA 2H9EL 3N8WB 1LQDA 3U7UG 1IGZA 2OYEP 4ZAEB 4XL1A 1HT5A 1FSBA 2VVVL 3ZYIB 5F1AA 1K37A 2P26A 2F9BL 3BT2A 2Y7ZB 2J34B 2I9BA 1J9CL 3SOVA 5L2ZL 3CFWA 1HZ8A 3FCSB 2I9AA 2BQWA 1FFMA 3LN1A 4RUTA 2Y5HL 4Y7BB 4ISIL 1COUA 1DVAL 1P9JA 3NTGA 4ZXXL 1LMJA 2P3FN 5E8DA 3MQEA 1C5MF 5JBAE 1IVOC 1IQFL 2W2OE 1TPGA 2Y82B 2WYGB 1DQBA 3TH3L 4OTJA 3KQBL 3KQCL 4RRZA 4BXWA 3KK6A 5JVYA 3HO5A 2VVUL 3SOQA 1I0UA 4O02B 1EPGA 1LMMA 1ADXA 1KLIL 3N8YB 1HRFA 5L30L 4MMYB 1XFEA 4ISHL 1EAIC 1NFWB 3Q7DA 5JBCE 1AUTL 1WU1B 5JVZA 4FM5A 1HJ7A 4JYUL 2P3UA 2VJ3A 1KLOA 2XBYL 2XC5L 2XBXL 1CEJA 1IQML 1CCFA 4YZUB 4A7IA 4Y6DB 1NFUB 1MQ6L 2RNLA 4CUFA 1XDTR 2W3IB 1FE2A 2BOHA 2VH6B 3CENL 3M36L 1ATBA 3ELAL 1MOXC 3NT1A 2Q1JB 1DX5I 1G2LB 4Y7AB 4ZHAB 5JB9E 1QFKL 3LAQA 2J2UB 2VWMK 3P5BL 5COXA 1HAFA 1NZIA 4JZFL 1IGXA 2PHBB 5JBBE 1F0SB 1CX2A 3CA7A 2GD4A 2Y81B 1CVUA 2KL7A 2DDUA 3BT1A 4LORA 5CISA 1L5GB 3S6XA 3RR3A 1F0RB 1NFXB 3KQEL 3GCXE 1EPIA 1EBVA 3GISX 1U8CB 4D0FA 1ATDA 1IQLL 2P3TA 1XKBA 3HS7A 3M37L 4AQTA 4BTIA 1HAEA 1NPEB 1ATAA 2VH0B 1APOA 1G1SA 3SW2A 3IITB 4A94C 2FD6A 3V65B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OLU A;  1IQJ L;  2Y38 A;  3TK5 B;  2WFT A;  1DIY A;  4RRX A;  3QH0 A;  2Y5G L;  1UZK A;  1YUK B;  4NG9 L;  2BOX A;  1SZB A;  1JV2 B;  3N8Y A;  5KN5 C;  3BPS E;  1HCG B;  1X7A L;  3LTG D;  1HT8 A;  2BZ6 L;  4NGA L;  1F7M A;  2WPI E;  1XKA L;  1IOE L;  2TGF A;  2XC4 L;  2FLR L;  3QMO A;  1URK A;  3LN0 A;  5L2Y L;  3IJE B;  1YUG A;  3KCG L;  1JBU L;  1LPZ A;  1WHF A;  1IP0 A;  3QCW A;  1WHE A;  3N8Z A;  2UWO B;  4X8V L;  3PGH A;  2P3F L;  1IQG L;  3HPT A;  1FAX L;  2J4I B;  5F19 A;  3LC5 B;  3R05 A;  4BDW A;  1EPJ A;  2WFX B;  2W2N E;  2YGP A;  1NQL B;  1P0S L;  3SOB B;  1U67 A;  2MGR A;  4ZXY L;  2PR3 B;  4CUE A;  3V64 C;  2B7D L;  3KL6 B;  1K36 A;  1FJS L;  5IKT A;  4YT6 L;  2BMG A;  2UWP B;  3N8V A;  4C16 A;  3LC3 B;  4OTY A;  2WPJ E;  5EGM B;  2J38 B;  2Y7X B;  4G1M B;  3ZYJ B;  4D90 A;  1DDX A;  4RS0 A;  4Z0K B;  3LTF B;  1G2M B;  1YUF A;  3GCW E;  4M11 A;  2MHP A;  3ZYG A;  3TGF A;  2WG3 C;  2XBW L;  3TBD A;  3HO3 A;  1YGC L;  1FAK L;  1IQE L;  1V3X B;  3ASI A;  2W2M E;  3H5C B;  5IKQ A;  5I46 L;  4NA9 L;  1EQG A;  3C9A C;  2D1J B;  6COX A;  1KSN B;  2NPR A;  3TK6 B;  1APQ A;  1UZJ A;  3N8X A;  1B9W A;  2Y5F L;  2BO2 A;  2VVC K;  1N7D A;  1G1Q A;  1G1R A;  2Y80 B;  1IQK L;  2XC0 L;  2XBV L;  1RFN B;  1EMO A;  3NTB A;  2FLG A;  3NJP C;  2VWN L;  1JL9 A;  1EMN A;  4Z6A L;  1IJQ A;  1ATE A;  1EGF A;  2EI7 B;  2P16 L;  4RRW A;  2PUQ L;  1UZQ A;  5JW1 A;  2BOU A;  4BTT A;  1G1T A;  1Z6C A;  2VWL L;  2W2Q E;  5CKN A;  1IOX A;  3MDL A;  5CKM A;  1IQH L;  4JYV L;  4TGF A;  1EZQ B;  5FDQ A;  4JZE L;  4D0E A;  2MGP A;  5IKV A;  5K0H B;  2RA0 L;  2G00 L;  3U73 A;  2K2S B;  4Y71 B;  1MQ5 L;  2UWL B;  1O5D L;  2JKH L;  1KIG L;  1W7X L;  1PXX A;  2K2T A;  3HS6 A;  2W3K B;  3HO4 A;  5CKQ A;  2WPL E;  2WPM E;  4BTU A;  4XLW A;  4Z0L A;  2AYL A;  3FFG L;  4X8T L;  1IQN L;  2FLB L;  2RHP A;  2WG4 B;  1L3Y A;  1F7E A;  2VWO L;  3EGF A;  4E1G A;  1N1I A;  1YO8 A;  1UZP A;  3FBY A;  4X8U L;  1EQH A;  1TOZ A;  3TZI A;  1Z6E L;  2W26 B;  1TLE A;  4BDX A;  1GK5 A;  4O1Z A;  1PGE A;  2FZZ L;  1CVW L;  2J94 B;  3Q3K B;  2WYJ B;  5JB8 E;  4XBM A;  3DEM A;  4X8S L;  1FF7 A;  3OLT A;  4RRY A;  1LPG A;  2J95 B;  3KQD L;  1A3P A;  2EI8 B;  4BXS A;  2OYU P;  3LIW B;  2KB9 A;  4CUD A;  4Y76 B;  4PH9 A;  1Q4G A;  1IQI L;  2WPK E;  1PTH A;  2P93 L;  3HS5 A;  2P28 B;  4M10 A;  2ADX A;  1LPK A;  5KIR A;  3ENS A;  1CQE A;  1W8B L;  3CS7 L;  1M1X B;  3N8W A;  4MMX B;  2P95 L;  1PFX L;  2YGO A;  2M74 A;  3F1S B;  1KLJ L;  1BF9 A;  2KV4 A;  2WPH E;  3F6U L;  3KRK A;  4CSY A;  2BOK L;  1NFY B;  4MMZ B;  4LMF A;  4COX A;  1CCV A;  1HRE A;  2W2P E;  1NT0 A;  4YT7 L;  2P94 L;  1HX2 A;  2BQ7 A;  2EI6 B;  4Y79 B;  1OB1 C;  2W86 A;  3K9X A;  5IKR A;  2BQ6 A;  3POY A;  1EPH A;  2CJI B;  4JZD L;  4ZH8 B;  1ZAQ A;  1PRH A;  2H9E L;  3N8W B;  1LQD A;  3U7U G;  1IGZ A;  2OYE P;  4ZAE B;  4XL1 A;  1HT5 A;  1FSB A;  2VVV L;  3ZYI B;  5F1A A;  1K37 A;  2P26 A;  2F9B L;  3BT2 A;  2Y7Z B;  2J34 B;  2I9B A;  1J9C L;  3SOV A;  5L2Z L;  3CFW A;  1HZ8 A;  3FCS B;  2I9A A;  2BQW A;  1FFM A;  3LN1 A;  4RUT A;  2Y5H L;  4Y7B B;  4ISI L;  1COU A;  1DVA L;  1P9J A;  3NTG A;  4ZXX L;  1LMJ A;  2P3F N;  5E8D A;  3MQE A;  1C5M F;  5JBA E;  1IVO C;  1IQF L;  2W2O E;  1TPG A;  2Y82 B;  2WYG B;  1DQB A;  3TH3 L;  4OTJ A;  3KQB L;  3KQC L;  4RRZ A;  4BXW A;  3KK6 A;  5JVY A;  3HO5 A;  2VVU L;  3SOQ A;  1I0U A;  4O02 B;  1EPG A;  1ADX A;  1KLI L;  3N8Y B;  1HRF A;  5L30 L;  4MMY B;  1XFE A;  4ISH L;  1EAI C;  1NFW B;  3Q7D A;  5JBC E;  1AUT L;  1WU1 B;  5JVZ A;  4FM5 A;  1HJ7 A;  4JYU L;  2P3U A;  2VJ3 A;  1KLO A;  2XBY L;  2XC5 L;  2XBX L;  1CEJ A;  1IQM L;  1CCF A;  4YZU B;  4A7I A;  4Y6D B;  1NFU B;  1MQ6 L;  2RNL A;  4CUF A;  1XDT R;  2W3I B;  1FE2 A;  2BOH A;  2VH6 B;  3CEN L;  3M36 L;  1ATB A;  3ELA L;  1MOX C;  3NT1 A;  2Q1J B;  1DX5 I;  1G2L B;  4Y7A B;  4ZHA B;  5JB9 E;  1QFK L;  3LAQ A;  2J2U B;  2VWM K;  3P5B L;  5COX A;  1HAF A;  1NZI A;  4JZF L;  1IGX A;  2PHB B;  5JBB E;  1F0S B;  1CX2 A;  3CA7 A;  2GD4 A;  2Y81 B;  1CVU A;  2KL7 A;  2DDU A;  3BT1 A;  4LOR A;  5CIS A;  1L5G B;  3RR3 A;  1F0R B;  1NFX B;  3KQE L;  3GCX E;  1EPI A;  1EBV A;  3GIS X;  1U8C B;  4D0F A;  1ATD A;  1IQL L;  2P3T A;  1XKB A;  3HS7 A;  3M37 L;  4AQT A;  4BTI A;  1HAE A;  1NPE B;  1ATA A;  2VH0 B;  1APO A;  1G1S A;  3SW2 A;  3IIT B;  2FD6 A;  3V65 B; 
#chains in the Genus database with same CATH topology
 3OLU A;  1IQJ L;  2Y38 A;  3TK5 B;  2WFT A;  1DIY A;  4RRX A;  3QH0 A;  2Y5G L;  1UZK A;  1YUK B;  4NG9 L;  2BOX A;  1SZB A;  1JV2 B;  3N8Y A;  5KN5 C;  3BPS E;  1HCG B;  1X7A L;  3LTG D;  1HT8 A;  2BZ6 L;  4NGA L;  1F7M A;  4GU3 A;  2WPI E;  1XKA L;  1IOE L;  2TGF A;  2XC4 L;  2FLR L;  3QMO A;  1URK A;  3LN0 A;  5L2Y L;  3IJE B;  1YUG A;  3KCG L;  1JBU L;  2H9E C;  1LPZ A;  1WHF A;  1IP0 A;  3QCW A;  1WHE A;  3N8Z A;  2UWO B;  4X8V L;  3PGH A;  2P3F L;  1IQG L;  3HPT A;  1FAX L;  2J4I B;  5F19 A;  3LC5 B;  3R05 A;  4BDW A;  1EPJ A;  2WFX B;  2W2N E;  2YGP A;  1NQL B;  1P0S L;  3SOB B;  1U67 A;  2MGR A;  4ZXY L;  2PR3 B;  1KKE A;  4CUE A;  3V64 C;  2B7D L;  3KL6 B;  1K36 A;  1FJS L;  5IKT A;  4YT6 L;  2BMG A;  2UWP B;  1V1I A;  3N8V A;  4C16 A;  3LC3 B;  4OTY A;  2WPJ E;  5EGM B;  2J38 B;  2Y7X B;  4G1M B;  3ZYJ B;  4D90 A;  1DDX A;  4RS0 A;  4Z0K B;  3LTF B;  1G2M B;  1YUF A;  3GCW E;  4M11 A;  2MHP A;  3ZYG A;  3TGF A;  2WG3 C;  2XBW L;  2YGQ A;  3TBD A;  3HO3 A;  1YGC L;  1FAK L;  1IQE L;  1V3X B;  3ASI A;  2W2M E;  3H5C B;  5IKQ A;  5I46 L;  4NA9 L;  1EQG A;  3C9A C;  2D1J B;  6COX A;  2KNI A;  1KSN B;  2NPR A;  3TK6 B;  1APQ A;  1UZJ A;  1LK9 A;  3N8X A;  1B9W A;  2Y5F L;  2BO2 A;  2VVC K;  1N7D A;  1G1Q A;  1G1R A;  2Y80 B;  1IQK L;  2XC0 L;  2JJL A;  2XBV L;  1RFN B;  1EMO A;  3NTB A;  2FLG A;  3NJP C;  2VWN L;  1JL9 A;  1EMN A;  4Z6A L;  1IJQ A;  1ATE A;  1EGF A;  2EI7 B;  2P16 L;  4RRW A;  2PUQ L;  1UZQ A;  5JW1 A;  2BOU A;  4BTT A;  1G1T A;  1Z6C A;  2VWL L;  2W2Q E;  5CKN A;  1IOX A;  3MDL A;  5CKM A;  1IQH L;  4JYV L;  4TGF A;  1EZQ B;  5FDQ A;  4JZE L;  4D0E A;  2MGP A;  5IKV A;  5K0H B;  2RA0 L;  2G00 L;  3U73 A;  2K2S B;  4Y71 B;  1MQ5 L;  2UWL B;  1O5D L;  2JKH L;  1KIG L;  1W7X L;  1PXX A;  2K2T A;  3HS6 A;  2W3K B;  3HO4 A;  5CKQ A;  2WPL E;  2WPM E;  4BTU A;  4XLW A;  4Z0L A;  2AYL A;  3FFG L;  4X8T L;  1IQN L;  2FLB L;  2RHP A;  2WG4 B;  1L3Y A;  1F7E A;  2BT8 A;  2VWO L;  3EGF A;  4E1G A;  1N1I A;  1YO8 A;  1UZP A;  3FBY A;  4X8U L;  1EQH A;  1TOZ A;  3TZI A;  1Z6E L;  2W26 B;  1TLE A;  4BDX A;  1GK5 A;  4O1Z A;  1PGE A;  2WZP P;  2FZZ L;  1CVW L;  2J94 B;  3Q3K B;  2WYJ B;  5JB8 E;  4XBM A;  3DEM A;  4X8S L;  1FF7 A;  3OLT A;  4RRY A;  1LPG A;  2J95 B;  3KQD L;  1A3P A;  2EI8 B;  4BXS A;  2OYU P;  3LIW B;  2KB9 A;  4CUD A;  4Y76 B;  4PH9 A;  1Q4G A;  1IQI L;  2WPK E;  1PTH A;  2P93 L;  3HS5 A;  2P28 B;  4M10 A;  2ADX A;  1LPK A;  5KIR A;  3ENS A;  1CQE A;  1W8B L;  2BT7 A;  2VRS A;  1M1X B;  3CS7 L;  3N8W A;  4MMX B;  2P95 L;  1PFX L;  2YGO A;  2M74 A;  3F1S B;  1KLJ L;  1BF9 A;  2KV4 A;  2WPH E;  3F6U L;  3KRK A;  4CSY A;  2BOK L;  1NFY B;  4MMZ B;  4LMF A;  4COX A;  1CCV A;  1HRE A;  2W2P E;  1NT0 A;  4YT7 L;  2P94 L;  1HX2 A;  2BQ7 A;  2EI6 B;  4Y79 B;  1OB1 C;  2W86 A;  3K9X A;  5IKR A;  2BQ6 A;  3POY A;  1EPH A;  2CJI B;  4JZD L;  4ZH8 B;  1QIU A;  1ZAQ A;  1PRH A;  2H9E L;  4GU4 A;  2HOR A;  3N8W B;  1LQD A;  3U7U G;  1IGZ A;  2OYE P;  4ZAE B;  4XL1 A;  1HT5 A;  1FSB A;  2VVV L;  3ZYI B;  5F1A A;  1K37 A;  2P26 A;  2F9B L;  3BT2 A;  2Y7Z B;  2J34 B;  2I9B A;  1J9C L;  3SOV A;  5L2Z L;  3CFW A;  1HZ8 A;  3FCS B;  2I9A A;  2BQW A;  1FFM A;  3LN1 A;  4RUT A;  2Y5H L;  4Y7B B;  4ISI L;  1COU A;  1DVA L;  1P9J A;  3NTG A;  4ZXX L;  1LMJ A;  2P3F N;  5E8D A;  3MQE A;  1C5M F;  5JBA E;  1IVO C;  1IQF L;  2W2O E;  1TPG A;  2Y82 B;  2WYG B;  1DQB A;  3TH3 L;  4OTJ A;  3KQB L;  3KQC L;  4RRZ A;  4BXW A;  3KK6 A;  5JVY A;  3HO5 A;  2VVU L;  3SOQ A;  1I0U A;  4O02 B;  1EPG A;  1LMM A;  1ADX A;  1KLI L;  3N8Y B;  1HRF A;  5L30 L;  4MMY B;  1XFE A;  4ISH L;  1EAI C;  1NFW B;  3Q7D A;  5JBC E;  1AUT L;  1WU1 B;  5JVZ A;  4FM5 A;  1HJ7 A;  4JYU L;  2P3U A;  2VJ3 A;  1KLO A;  2XBY L;  2XC5 L;  2XBX L;  1CEJ A;  1IQM L;  1CCF A;  4YZU B;  4A7I A;  4Y6D B;  1NFU B;  1MQ6 L;  2RNL A;  4CUF A;  1XDT R;  2W3I B;  1FE2 A;  2BOH A;  2VH6 B;  3CEN L;  3M36 L;  1V1H A;  1ATB A;  3ELA L;  1MOX C;  3NT1 A;  2Q1J B;  1DX5 I;  1G2L B;  4Y7A B;  4ZHA B;  5JB9 E;  1QFK L;  3LAQ A;  2J2U B;  2VWM K;  3P5B L;  5COX A;  1HAF A;  1NZI A;  4JZF L;  2HOX A;  1IGX A;  2PHB B;  5JBB E;  1F0S B;  1CX2 A;  3CA7 A;  2GD4 A;  2Y81 B;  1CVU A;  2KL7 A;  2DDU A;  3BT1 A;  4LOR A;  5CIS A;  1L5G B;  3S6X A;  3RR3 A;  1F0R B;  1NFX B;  3KQE L;  3GCX E;  1EPI A;  1EBV A;  3GIS X;  1U8C B;  4D0F A;  1ATD A;  1IQL L;  2P3T A;  1XKB A;  3HS7 A;  3M37 L;  4AQT A;  4BTI A;  1HAE A;  2BSF A;  1NPE B;  1ATA A;  2VH0 B;  1APO A;  1G1S A;  3SW2 A;  3IIT B;  4A94 C;  2FD6 A;  3V65 B; 
#chains in the Genus database with same CATH homology
 3OLU A;  1IQJ L;  2Y38 A;  3TK5 B;  2WFT A;  1DIY A;  4RRX A;  3QH0 A;  2Y5G L;  1UZK A;  1YUK B;  4NG9 L;  2BOX A;  1SZB A;  1JV2 B;  3N8Y A;  5KN5 C;  3BPS E;  1HCG B;  1X7A L;  3LTG D;  1HT8 A;  2BZ6 L;  4NGA L;  1F7M A;  2WPI E;  1XKA L;  1IOE L;  2TGF A;  2XC4 L;  2FLR L;  3QMO A;  1URK A;  3LN0 A;  5L2Y L;  3IJE B;  1YUG A;  3KCG L;  1JBU L;  2H9E C;  1LPZ A;  1WHF A;  1IP0 A;  3QCW A;  1WHE A;  3N8Z A;  2UWO B;  4X8V L;  3PGH A;  2P3F L;  1IQG L;  3HPT A;  1FAX L;  2J4I B;  5F19 A;  3LC5 B;  3R05 A;  4BDW A;  1EPJ A;  2WFX B;  2W2N E;  2YGP A;  1NQL B;  1P0S L;  3SOB B;  1U67 A;  2MGR A;  4ZXY L;  2PR3 B;  4CUE A;  3V64 C;  2B7D L;  3KL6 B;  1K36 A;  1FJS L;  5IKT A;  4YT6 L;  2BMG A;  2UWP B;  3N8V A;  4C16 A;  3LC3 B;  4OTY A;  2WPJ E;  5EGM B;  2J38 B;  2Y7X B;  4G1M B;  3ZYJ B;  4D90 A;  1DDX A;  4RS0 A;  4Z0K B;  3LTF B;  1G2M B;  1YUF A;  3GCW E;  4M11 A;  2MHP A;  3ZYG A;  3TGF A;  2WG3 C;  2XBW L;  2YGQ A;  3TBD A;  3HO3 A;  1YGC L;  1FAK L;  1IQE L;  1V3X B;  3ASI A;  2W2M E;  3H5C B;  5IKQ A;  5I46 L;  4NA9 L;  1EQG A;  3C9A C;  2D1J B;  6COX A;  2KNI A;  1KSN B;  2NPR A;  3TK6 B;  1APQ A;  1UZJ A;  3N8X A;  1B9W A;  2Y5F L;  2BO2 A;  2VVC K;  1N7D A;  1G1Q A;  1G1R A;  2Y80 B;  1IQK L;  2XC0 L;  2XBV L;  1RFN B;  1EMO A;  3NTB A;  2FLG A;  3NJP C;  2VWN L;  1JL9 A;  1EMN A;  4Z6A L;  1IJQ A;  1ATE A;  1EGF A;  2EI7 B;  2P16 L;  4RRW A;  2PUQ L;  1UZQ A;  5JW1 A;  2BOU A;  4BTT A;  1G1T A;  1Z6C A;  2VWL L;  2W2Q E;  5CKN A;  1IOX A;  3MDL A;  5CKM A;  1IQH L;  4JYV L;  4TGF A;  1EZQ B;  5FDQ A;  4JZE L;  4D0E A;  2MGP A;  5IKV A;  5K0H B;  2RA0 L;  2G00 L;  3U73 A;  2K2S B;  4Y71 B;  1MQ5 L;  2UWL B;  1O5D L;  2JKH L;  1KIG L;  1W7X L;  1PXX A;  2K2T A;  3HS6 A;  2W3K B;  3HO4 A;  5CKQ A;  2WPL E;  2WPM E;  4BTU A;  4XLW A;  4Z0L A;  2AYL A;  3FFG L;  4X8T L;  1IQN L;  2FLB L;  2RHP A;  2WG4 B;  1L3Y A;  1F7E A;  2VWO L;  3EGF A;  4E1G A;  1N1I A;  1YO8 A;  1UZP A;  3FBY A;  4X8U L;  1EQH A;  1TOZ A;  3TZI A;  1Z6E L;  2W26 B;  1TLE A;  4BDX A;  1GK5 A;  4O1Z A;  1PGE A;  2WZP P;  2FZZ L;  1CVW L;  2J94 B;  3Q3K B;  2WYJ B;  5JB8 E;  4XBM A;  3DEM A;  4X8S L;  1FF7 A;  3OLT A;  4RRY A;  1LPG A;  2J95 B;  3KQD L;  1A3P A;  2EI8 B;  4BXS A;  2OYU P;  3LIW B;  2KB9 A;  4CUD A;  4Y76 B;  4PH9 A;  1Q4G A;  1IQI L;  2WPK E;  1PTH A;  2P93 L;  3HS5 A;  2P28 B;  4M10 A;  2ADX A;  1LPK A;  5KIR A;  3ENS A;  1CQE A;  1W8B L;  3CS7 L;  1M1X B;  3N8W A;  4MMX B;  2P95 L;  1PFX L;  2YGO A;  2M74 A;  3F1S B;  1KLJ L;  1BF9 A;  2KV4 A;  2WPH E;  3F6U L;  3KRK A;  4CSY A;  2BOK L;  1NFY B;  4MMZ B;  4LMF A;  4COX A;  1CCV A;  1HRE A;  2W2P E;  1NT0 A;  4YT7 L;  2P94 L;  1HX2 A;  2BQ7 A;  2EI6 B;  4Y79 B;  1OB1 C;  2W86 A;  3K9X A;  5IKR A;  2BQ6 A;  3POY A;  1EPH A;  2CJI B;  4JZD L;  4ZH8 B;  1ZAQ A;  1PRH A;  2H9E L;  3N8W B;  1LQD A;  3U7U G;  1IGZ A;  2OYE P;  4ZAE B;  4XL1 A;  1HT5 A;  1FSB A;  2VVV L;  3ZYI B;  5F1A A;  1K37 A;  2P26 A;  2F9B L;  3BT2 A;  2Y7Z B;  2J34 B;  2I9B A;  1J9C L;  3SOV A;  5L2Z L;  3CFW A;  1HZ8 A;  3FCS B;  2I9A A;  2BQW A;  1FFM A;  3LN1 A;  4RUT A;  2Y5H L;  4Y7B B;  4ISI L;  1COU A;  1DVA L;  1P9J A;  3NTG A;  4ZXX L;  1LMJ A;  2P3F N;  5E8D A;  3MQE A;  1C5M F;  5JBA E;  1IVO C;  1IQF L;  2W2O E;  1TPG A;  2Y82 B;  2WYG B;  1DQB A;  3TH3 L;  4OTJ A;  3KQB L;  3KQC L;  4RRZ A;  4BXW A;  3KK6 A;  5JVY A;  3HO5 A;  2VVU L;  3SOQ A;  1I0U A;  4O02 B;  1EPG A;  1LMM A;  1ADX A;  1KLI L;  3N8Y B;  1HRF A;  5L30 L;  4MMY B;  1XFE A;  4ISH L;  1EAI C;  1NFW B;  3Q7D A;  5JBC E;  1AUT L;  1WU1 B;  5JVZ A;  4FM5 A;  1HJ7 A;  4JYU L;  2P3U A;  2VJ3 A;  1KLO A;  2XBY L;  2XC5 L;  2XBX L;  1CEJ A;  1IQM L;  1CCF A;  4YZU B;  4A7I A;  4Y6D B;  1NFU B;  1MQ6 L;  2RNL A;  4CUF A;  1XDT R;  2W3I B;  1FE2 A;  2BOH A;  2VH6 B;  3CEN L;  3M36 L;  1ATB A;  3ELA L;  1MOX C;  3NT1 A;  2Q1J B;  1DX5 I;  1G2L B;  4Y7A B;  4ZHA B;  5JB9 E;  1QFK L;  3LAQ A;  2J2U B;  2VWM K;  3P5B L;  5COX A;  1HAF A;  1NZI A;  4JZF L;  1IGX A;  2PHB B;  5JBB E;  1F0S B;  1CX2 A;  3CA7 A;  2GD4 A;  2Y81 B;  1CVU A;  2KL7 A;  2DDU A;  3BT1 A;  4LOR A;  5CIS A;  1L5G B;  3S6X A;  3RR3 A;  1F0R B;  1NFX B;  3KQE L;  3GCX E;  1EPI A;  1EBV A;  3GIS X;  1U8C B;  4D0F A;  1ATD A;  1IQL L;  2P3T A;  1XKB A;  3HS7 A;  3M37 L;  4AQT A;  4BTI A;  1HAE A;  1NPE B;  1ATA A;  2VH0 B;  1APO A;  1G1S A;  3SW2 A;  3IIT B;  4A94 C;  2FD6 A;  3V65 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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