1LPZA

Crystal structure of fxa in complex with 41.
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and Quantitative Structure-Activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Blood coagulation factor Xa
total genus 10
structure length 53
sequence length 53
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2002-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00008 EGF EGF-like domain
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1lpzA00
1FSBA 5JVZA 3GCWE 3OLTA 3N8YB 1W8BL 3HO5A 1KLIL 1CEJA 3CENL 5JBBE 2P28B 2Y82B 4ISIL 2B7DL 2UWLB 4LORA 1L5GB 1HT8A 2JKHL 3BPSE 4BTIA 2NPRA 2W2PE 3BT2A 3KQCL 1ATDA 3HO3A 1G1TA 1HREA 4RRZA 3V65B 1UZPA 2XBXL 2VWNL 4Y7BB 2KB9A 3N8WA 2W86A 3N8ZA 2WFXB 4JZEL 1JL9A 1GK5A 1KLJL 1Z6EL 3EGFA 1DQBA 1G2LB 2MGRA 4O1ZA 1G2MB 1X7AL 1HT5A 2Q1JB 1HAEA 1P9JA 1IGZA 3ELAL 2BMGA 3HPTA 3TBDA 4ZAEB 4CSYA 5IKTA 1F7EA 1YUFA 2UWOB 2BOXA 1G1QA 4RS0A 1IQIL 3N8XA 3QH0A 3TK6B 2VWLL 1DVAL 1B9WA 5K0HB 2XC5L 1RFNB 4G1MB 1EAIC 1FAKL 2P26A 4Y71B 1PGEA 3SOVA 1IQEL 1UZQA 5IKQA 3TGFA 3F1SB 3P5BL 4JZFL 2BQ6A 3N8YA 4ZXXL 3ZYGA 4ZH8B 3HO4A 3ZYJB 1DDXA 3FCSB 2K2SB 3V64C 3NT1A 4XL1A 3MQEA 1TLEA 2KV4A 4C16A 1EPGA 3M36L 2CJIB 1F0SB 2FZZL 1G1SA 4CUDA 2XBWL 3CA7A 3LN0A 5F19A 5F1AA 5JB9E 2J2UB 3GISX 2VWMK 3LTFB 2OYEP 3SOBB 3M37L 2H9EL 3HS7A 5L30L 3N8VA 1F0RB 3R05A 5JBCE 5JVYA 1WU1B 1FE2A 2VVUL 1NFYB 2MHPA 2RNLA 1IQGL 3TK5B 4PH9A 3K9XA 2Y38A 1F7MA 2PHBB 2RHPA 3FFGL 1W7XL 1P0SL 2VJ3A 3QCWA 2Y5GL 3KQEL 2DDUA 3POYA 1XKBA 4ISHL 4M10A 1EMNA 1FFMA 5L2YL 1IQLL 3Q7DA 3CFWA 5FDQA 4Z6AL 2J94B 4YZUB 2ADXA 3U7UG 1EZQB 2YGPA 3ZYIB 4NG9L 3NTBA 4Z0LA 2W3KB 1TOZA 2GD4A 4A7IA 3LTGD 4X8VL 3DEMA 1ADXA 4FM5A 4ZXYL 1NPEB 2M74A 1QFKL 4CUEA 1CCVA 1O5DL 1HX2A 1UZKA 1EBVA 1DX5I 2WYGB 1PTHA 3H5CB 1K37A 2XBVL 5KN5C 2I9BA 1ATEA 2BOUA 3FBYA 2WFTA 2WPLE 1HAFA 1MQ6L 1WHEA 2WG4B 5JW1A 4AQTA 4BXWA 5CKMA 1IQML 5L2ZL 2W2QE 2EI8B 1NFXB 1XFEA 1YUKB 1EPJA 4RRWA 2KL7A 1BF9A 4ZHAB 2W26B 4CUFA 2TGFA 2FLRL 4Y7AB 1IQKL 3HS6A 2FLGA 1IVOC 2P3UA 2W2NE 3IJEB 3PGHA 4NA9L 1COUA 1LPGA 4BXSA 1URKA 2Y80B 3Q3KB 1XDTR 1FF7A 5CKQA 3KK6A 1FAXL 1TPGA 2P93L 3RR3A 1NT0A 2BO2A 5CISA 2EI7B 5I46L 2I9AA 2G00L 3LC5B 4XLWA 4RUTA 1YGCL 2WYJB 1Z6CA 4MMZB 4Y79B 4Z0KB 1M1XB 4E1GA 1ATAA 1IQHL 4BTTA 4D0FA 2BOKL 2XBYL 1OB1C 4D90A 1KLOA 1APOA 2FD6A 2P3FN 3U73A 1IOEL 2J95B 1NFWB 4X8UL 4LMFA 1SZBA 1IP0A 1CVUA 4BTUA 4YT7L 3KQDL 4RRYA 1FJSL 1CVWL 2J38B 2K2TA 3SW2A 2XC0L 4COXA 1EMOA 2RA0L 2P16L 4O02B 5COXA 3BT1A 1L3YA 1J9CL 3KCGL 2PR3B 1HCGB 1HJ7A 1IQJL 2WG3C 1EGFA 1LPKA 1APQA 3HS5A 4MMYB 2P94L 2XC4L 3ASIA 1HRFA 3MDLA 1PFXL 2VVCK 2MGPA 1ZAQA 2W2ME 2VH0B 2WPHE 3ENSA 5CKNA 2OYUP 2Y7ZB 1AUTL 5E8DA 1CQEA 4JYUL 1WHFA 2VWOL 2Y7XB 3KRKA 3LAQA 4BDWA 2PUQL 4JYVL 2Y5FL 2BQWA 1NZIA 1U8CB 5KIRA 1NQLB 4X8SL 1YO8A 1K36A 4BDXA 3OLUA 5JB8E 2P95L 1I0UA 1JBUL 1CCFA 2FLBL 3NTGA 4NGAL 1UZJA 1XKAL 1IQFL 5EGMB 3TH3L 5IKVA 2J34B 4YT6L 5IKRA 4XBMA 1U67A 4M11A 4Y6DB 1KSNB 4OTYA 1G1RA 2W2OE 3LIWB 1IJQA 1IOXA 2J4IB 2Y81B 1LMJA 2AYLA 4D0EA 3C9AC 1IGXA 2EI6B 1N1IA 1MOXC 1LPZA 1C5MF 2WPJE 3KL6B 1Q4GA 3F6UL 3IITB 3KQBL 4MMXB 2UWPB 2P3TA 4TGFA 1NFUB 1ATBA 4RRXA 3N8WB 1PRHA 2VVVL 1DIYA 2WPIE 2BQ7A 2BZ6L 1EQHA 2D1JB 1YUGA 2BOHA 1HZ8A 1EQGA 2F9BL 1MQ5L 1IQNL 1CX2A 1KIGL 3LC3B 3LN1A 3GCXE 2WPKE 5JBAE 2P3FL 1EPIA 2Y5HL 4OTJA 3CS7L 1PXXA 1JV2B 1N7DA 2WPME 3TZIA 2W3IB 1EPHA 6COXA 1A3PA 2VH6B 2YGOA 1V3XB 3QMOA 3SOQA 4JZDL 1LQDA 4Y76B 4X8TL 3NJPC
chains in the Genus database with same CATH superfamily
2VRSA 1FSBA 5JVZA 3GCWE 3OLTA 3N8YB 1W8BL 3HO5A 1KLIL 1CEJA 3CENL 5JBBE 2P28B 2Y82B 4ISIL 2B7DL 2UWLB 4LORA 1L5GB 1HT8A 2JKHL 3BPSE 4BTIA 2NPRA 2W2PE 3BT2A 3KQCL 1ATDA 3HO3A 1G1TA 1HREA 4RRZA 3V65B 1UZPA 4GU4A 2XBXL 2VWNL 4Y7BB 2KB9A 3N8WA 2W86A 3N8ZA 2WFXB 4JZEL 1JL9A 1GK5A 1KLJL 1Z6EL 3EGFA 1DQBA 1G2LB 2MGRA 4O1ZA 1G2MB 1X7AL 1HT5A 2Q1JB 1HAEA 1P9JA 1IGZA 1V1IA 3ELAL 2BMGA 3HPTA 3TBDA 2BSFA 4ZAEB 4CSYA 5IKTA 1F7EA 1YUFA 2UWOB 2BOXA 1G1QA 4RS0A 1IQIL 3N8XA 3QH0A 3TK6B 2VWLL 1DVAL 1B9WA 5K0HB 2XC5L 1RFNB 4G1MB 1EAIC 1FAKL 2P26A 4Y71B 1PGEA 3SOVA 1IQEL 1UZQA 5IKQA 3TGFA 3F1SB 3P5BL 4JZFL 2BQ6A 3N8YA 4ZXXL 3ZYGA 4ZH8B 3HO4A 3ZYJB 1DDXA 3FCSB 2K2SB 3V64C 3NT1A 4XL1A 3MQEA 1TLEA 4A94C 2KV4A 4C16A 1EPGA 3M36L 2CJIB 1F0SB 2FZZL 1G1SA 4CUDA 2XBWL 3CA7A 3LN0A 5F19A 5F1AA 5JB9E 2J2UB 3GISX 2VWMK 3LTFB 2OYEP 3SOBB 3M37L 2H9EL 3HS7A 5L30L 3N8VA 1F0RB 3R05A 5JBCE 5JVYA 1WU1B 1FE2A 2VVUL 1NFYB 2MHPA 2RNLA 1IQGL 3TK5B 4PH9A 3K9XA 2Y38A 1F7MA 2PHBB 2RHPA 3FFGL 1W7XL 1P0SL 2VJ3A 3QCWA 2Y5GL 3KQEL 2DDUA 3POYA 1XKBA 4ISHL 4M10A 1EMNA 1FFMA 5L2YL 1IQLL 3Q7DA 3CFWA 5FDQA 4Z6AL 2J94B 4YZUB 2ADXA 3U7UG 1EZQB 2YGPA 3ZYIB 4NG9L 3NTBA 4Z0LA 2W3KB 1TOZA 2GD4A 4A7IA 3LTGD 4X8VL 3DEMA 1ADXA 4FM5A 4ZXYL 1NPEB 2M74A 1QFKL 4CUEA 1CCVA 1O5DL 1HX2A 1UZKA 1EBVA 1DX5I 2WYGB 1PTHA 3H5CB 1K37A 2XBVL 5KN5C 2I9BA 1ATEA 2BOUA 3FBYA 2WFTA 2WPLE 1HAFA 1MQ6L 1WHEA 2WZPP 2WG4B 2H9EC 5JW1A 4AQTA 4BXWA 1LMMA 1IQML 5CKMA 5L2ZL 2W2QE 2EI8B 1NFXB 1XFEA 1YUKB 1EPJA 4RRWA 2KL7A 1BF9A 4ZHAB 2W26B 4CUFA 2TGFA 2FLRL 4Y7AB 1IQKL 3HS6A 2FLGA 1IVOC 2P3UA 2HOXA 2W2NE 3IJEB 3PGHA 4NA9L 1COUA 1LPGA 4BXSA 1URKA 2Y80B 3Q3KB 1XDTR 1FF7A 5CKQA 3KK6A 1FAXL 1V1HA 1TPGA 2P93L 3RR3A 1NT0A 2BO2A 5CISA 2EI7B 5I46L 2I9AA 2G00L 3LC5B 2KNIA 4XLWA 4RUTA 1YGCL 2WYJB 1Z6CA 4MMZB 4Y79B 4Z0KB 1M1XB 4E1GA 1ATAA 1IQHL 4BTTA 4D0FA 2BOKL 2XBYL 1OB1C 4D90A 1KLOA 1APOA 2FD6A 2P3FN 3U73A 1IOEL 2J95B 1NFWB 4X8UL 4LMFA 1SZBA 1IP0A 1CVUA 4BTUA 3S6XA 4YT7L 3KQDL 4RRYA 1FJSL 1CVWL 2J38B 2K2TA 3SW2A 2XC0L 4COXA 1EMOA 2RA0L 2P16L 4O02B 5COXA 3BT1A 1L3YA 1J9CL 3KCGL 2PR3B 1HCGB 1HJ7A 1IQJL 2WG3C 1EGFA 1LPKA 1APQA 3HS5A 4MMYB 2P94L 2XC4L 3ASIA 1HRFA 3MDLA 1PFXL 2VVCK 2MGPA 1ZAQA 2W2ME 2VH0B 2WPHE 2YGQA 3ENSA 5CKNA 2OYUP 2Y7ZB 1AUTL 5E8DA 1CQEA 4JYUL 1WHFA 2VWOL 1LK9A 2Y7XB 3KRKA 3LAQA 4BDWA 2PUQL 4JYVL 2Y5FL 2BQWA 1NZIA 1U8CB 5KIRA 1NQLB 4X8SL 1YO8A 1K36A 2JJLA 4BDXA 3OLUA 5JB8E 2P95L 1I0UA 1JBUL 1CCFA 2FLBL 3NTGA 4NGAL 1UZJA 1XKAL 1IQFL 5EGMB 3TH3L 5IKVA 2J34B 4YT6L 5IKRA 4XBMA 1U67A 4M11A 4Y6DB 1KSNB 4OTYA 1G1RA 2W2OE 3LIWB 2BT7A 1IJQA 1IOXA 1QIUA 2J4IB 2Y81B 1LMJA 2AYLA 4D0EA 3C9AC 1IGXA 2EI6B 1N1IA 1MOXC 1LPZA 1C5MF 2WPJE 3KL6B 1Q4GA 3F6UL 3IITB 3KQBL 4MMXB 2UWPB 2P3TA 4TGFA 1NFUB 1ATBA 4RRXA 4GU3A 3N8WB 1PRHA 2VVVL 1DIYA 2WPIE 2BQ7A 2BZ6L 1EQHA 2D1JB 1YUGA 2HORA 2BOHA 1HZ8A 1EQGA 2F9BL 1MQ5L 1IQNL 1KKEA 1CX2A 1KIGL 3LC3B 3LN1A 3GCXE 2WPKE 5JBAE 2P3FL 1EPIA 2Y5HL 4OTJA 3CS7L 2BT8A 1PXXA 1JV2B 1N7DA 2WPME 3TZIA 2W3IB 1EPHA 6COXA 1A3PA 2VH6B 2YGOA 1V3XB 3QMOA 3SOQA 4JZDL 1LQDA 4Y76B 4X8TL 3NJPC
chains in the Genus database with same CATH topology
1FSBA 5JVZA 3GCWE 3OLTA 3N8YB 1W8BL 3HO5A 1KLIL 1CEJA 3CENL 5JBBE 2P28B 2Y82B 4ISIL 2B7DL 2UWLB 4LORA 1L5GB 1HT8A 2JKHL 3BPSE 4BTIA 2NPRA 2W2PE 3BT2A 3KQCL 1ATDA 3HO3A 1G1TA 1HREA 4RRZA 3V65B 1UZPA 2XBXL 2VWNL 4Y7BB 2KB9A 3N8WA 2W86A 3N8ZA 2WFXB 4JZEL 1JL9A 1GK5A 1KLJL 1Z6EL 3EGFA 1DQBA 1G2LB 2MGRA 4O1ZA 1G2MB 1X7AL 1HT5A 2Q1JB 1HAEA 1P9JA 1IGZA 3ELAL 2BMGA 3HPTA 3TBDA 4ZAEB 4CSYA 5IKTA 1F7EA 1YUFA 2UWOB 2BOXA 1G1QA 4RS0A 1IQIL 3N8XA 3QH0A 3TK6B 2VWLL 1DVAL 1B9WA 5K0HB 2XC5L 1RFNB 4G1MB 1EAIC 1FAKL 2P26A 4Y71B 1PGEA 3SOVA 1IQEL 1UZQA 5IKQA 3TGFA 3F1SB 3P5BL 4JZFL 2BQ6A 3N8YA 4ZXXL 3ZYGA 4ZH8B 3HO4A 3ZYJB 1DDXA 3FCSB 2K2SB 3V64C 3NT1A 4XL1A 3MQEA 1TLEA 4A94C 2KV4A 4C16A 1EPGA 3M36L 2CJIB 1F0SB 2FZZL 1G1SA 4CUDA 2XBWL 3CA7A 3LN0A 5F19A 5F1AA 5JB9E 2J2UB 3GISX 2VWMK 3LTFB 2OYEP 3SOBB 3M37L 2H9EL 3HS7A 5L30L 3N8VA 1F0RB 3R05A 5JBCE 5JVYA 1WU1B 1FE2A 2VVUL 1NFYB 2MHPA 2RNLA 1IQGL 3TK5B 4PH9A 3K9XA 2Y38A 1F7MA 2PHBB 2RHPA 3FFGL 1W7XL 1P0SL 2VJ3A 3QCWA 2Y5GL 3KQEL 2DDUA 3POYA 1XKBA 4ISHL 4M10A 1EMNA 1FFMA 5L2YL 1IQLL 3Q7DA 3CFWA 5FDQA 4Z6AL 2J94B 4YZUB 2ADXA 3U7UG 1EZQB 2YGPA 3ZYIB 4NG9L 3NTBA 4Z0LA 2W3KB 1TOZA 2GD4A 4A7IA 3LTGD 4X8VL 3DEMA 1ADXA 4FM5A 4ZXYL 1NPEB 2M74A 1QFKL 4CUEA 1CCVA 1O5DL 1HX2A 1UZKA 1EBVA 1DX5I 2WYGB 1PTHA 3H5CB 1K37A 2XBVL 5KN5C 2I9BA 1ATEA 2BOUA 3FBYA 2WFTA 2WPLE 1HAFA 1MQ6L 1WHEA 2WZPP 2WG4B 2H9EC 5JW1A 4AQTA 4BXWA 1LMMA 1IQML 5CKMA 5L2ZL 2W2QE 2EI8B 1NFXB 1XFEA 1YUKB 1EPJA 4RRWA 2KL7A 1BF9A 4ZHAB 2W26B 4CUFA 2TGFA 2FLRL 4Y7AB 1IQKL 3HS6A 2FLGA 1IVOC 2P3UA 2W2NE 3IJEB 3PGHA 4NA9L 1COUA 1LPGA 4BXSA 1URKA 2Y80B 3Q3KB 1XDTR 1FF7A 5CKQA 3KK6A 1FAXL 1TPGA 2P93L 3RR3A 1NT0A 2BO2A 5CISA 2EI7B 5I46L 2I9AA 2G00L 3LC5B 2KNIA 4XLWA 4RUTA 1YGCL 2WYJB 1Z6CA 4MMZB 4Y79B 4Z0KB 1M1XB 4E1GA 1ATAA 1IQHL 4BTTA 4D0FA 2BOKL 2XBYL 1OB1C 4D90A 1KLOA 1APOA 2FD6A 2P3FN 3U73A 1IOEL 2J95B 1NFWB 4X8UL 4LMFA 1SZBA 1IP0A 1CVUA 4BTUA 3S6XA 4YT7L 3KQDL 4RRYA 1FJSL 1CVWL 2J38B 2K2TA 3SW2A 2XC0L 4COXA 1EMOA 2RA0L 2P16L 4O02B 5COXA 3BT1A 1L3YA 1J9CL 3KCGL 2PR3B 1HCGB 1HJ7A 1IQJL 2WG3C 1EGFA 1LPKA 1APQA 3HS5A 4MMYB 2P94L 2XC4L 3ASIA 1HRFA 3MDLA 1PFXL 2VVCK 2MGPA 1ZAQA 2W2ME 2VH0B 2WPHE 2YGQA 3ENSA 5CKNA 2OYUP 2Y7ZB 1AUTL 5E8DA 1CQEA 4JYUL 1WHFA 2VWOL 2Y7XB 3KRKA 3LAQA 4BDWA 2PUQL 4JYVL 2Y5FL 2BQWA 1NZIA 1U8CB 5KIRA 1NQLB 4X8SL 1YO8A 1K36A 4BDXA 3OLUA 5JB8E 2P95L 1I0UA 1JBUL 1CCFA 2FLBL 3NTGA 4NGAL 1UZJA 1XKAL 1IQFL 5EGMB 3TH3L 5IKVA 2J34B 4YT6L 5IKRA 4XBMA 1U67A 4M11A 4Y6DB 1KSNB 4OTYA 1G1RA 2W2OE 3LIWB 1IJQA 1IOXA 2J4IB 2Y81B 1LMJA 2AYLA 4D0EA 3C9AC 1IGXA 2EI6B 1N1IA 1MOXC 1LPZA 1C5MF 2WPJE 3KL6B 1Q4GA 3F6UL 3IITB 3KQBL 4MMXB 2UWPB 2P3TA 4TGFA 1NFUB 1ATBA 4RRXA 3N8WB 1PRHA 2VVVL 1DIYA 2WPIE 2BQ7A 2BZ6L 1EQHA 2D1JB 1YUGA 2BOHA 1HZ8A 1EQGA 2F9BL 1MQ5L 1IQNL 1CX2A 1KIGL 3LC3B 3LN1A 3GCXE 2WPKE 5JBAE 2P3FL 1EPIA 2Y5HL 4OTJA 3CS7L 1PXXA 1JV2B 1N7DA 2WPME 3TZIA 2W3IB 1EPHA 6COXA 1A3PA 2VH6B 2YGOA 1V3XB 3QMOA 3SOQA 4JZDL 1LQDA 4Y76B 4X8TL 3NJPC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FSB A;  5JVZ A;  3GCW E;  3OLT A;  3N8Y B;  1W8B L;  3HO5 A;  1KLI L;  1CEJ A;  3CEN L;  5JBB E;  2P28 B;  2Y82 B;  4ISI L;  2B7D L;  2UWL B;  4LOR A;  1L5G B;  1HT8 A;  2JKH L;  3BPS E;  4BTI A;  2NPR A;  2W2P E;  3BT2 A;  3KQC L;  1ATD A;  3HO3 A;  1G1T A;  1HRE A;  4RRZ A;  3V65 B;  1UZP A;  2XBX L;  2VWN L;  4Y7B B;  2KB9 A;  3N8W A;  2W86 A;  3N8Z A;  2WFX B;  4JZE L;  1JL9 A;  1GK5 A;  1KLJ L;  1Z6E L;  3EGF A;  1DQB A;  1G2L B;  2MGR A;  4O1Z A;  1G2M B;  1X7A L;  1HT5 A;  2Q1J B;  1HAE A;  1P9J A;  1IGZ A;  3ELA L;  2BMG A;  3HPT A;  3TBD A;  4ZAE B;  4CSY A;  5IKT A;  1F7E A;  1YUF A;  2UWO B;  2BOX A;  1G1Q A;  4RS0 A;  1IQI L;  3N8X A;  3QH0 A;  3TK6 B;  2VWL L;  1DVA L;  1B9W A;  5K0H B;  2XC5 L;  1RFN B;  4G1M B;  1EAI C;  1FAK L;  2P26 A;  4Y71 B;  1PGE A;  3SOV A;  1IQE L;  1UZQ A;  5IKQ A;  3TGF A;  3F1S B;  3P5B L;  4JZF L;  2BQ6 A;  3N8Y A;  4ZXX L;  3ZYG A;  4ZH8 B;  3HO4 A;  3ZYJ B;  1DDX A;  3FCS B;  2K2S B;  3V64 C;  3NT1 A;  4XL1 A;  3MQE A;  1TLE A;  2KV4 A;  4C16 A;  1EPG A;  3M36 L;  2CJI B;  1F0S B;  2FZZ L;  1G1S A;  4CUD A;  2XBW L;  3CA7 A;  3LN0 A;  5F19 A;  5F1A A;  5JB9 E;  2J2U B;  3GIS X;  2VWM K;  3LTF B;  2OYE P;  3SOB B;  3M37 L;  2H9E L;  3HS7 A;  5L30 L;  3N8V A;  1F0R B;  3R05 A;  5JBC E;  5JVY A;  1WU1 B;  1FE2 A;  2VVU L;  1NFY B;  2MHP A;  2RNL A;  1IQG L;  3TK5 B;  4PH9 A;  3K9X A;  2Y38 A;  1F7M A;  2PHB B;  2RHP A;  3FFG L;  1W7X L;  1P0S L;  2VJ3 A;  3QCW A;  2Y5G L;  3KQE L;  2DDU A;  3POY A;  1XKB A;  4ISH L;  4M10 A;  1EMN A;  1FFM A;  5L2Y L;  1IQL L;  3Q7D A;  3CFW A;  5FDQ A;  4Z6A L;  2J94 B;  4YZU B;  2ADX A;  3U7U G;  1EZQ B;  2YGP A;  3ZYI B;  4NG9 L;  3NTB A;  4Z0L A;  2W3K B;  1TOZ A;  2GD4 A;  4A7I A;  3LTG D;  4X8V L;  3DEM A;  1ADX A;  4FM5 A;  4ZXY L;  1NPE B;  2M74 A;  1QFK L;  4CUE A;  1CCV A;  1O5D L;  1HX2 A;  1UZK A;  1EBV A;  1DX5 I;  2WYG B;  1PTH A;  3H5C B;  1K37 A;  2XBV L;  5KN5 C;  2I9B A;  1ATE A;  2BOU A;  3FBY A;  2WFT A;  2WPL E;  1HAF A;  1MQ6 L;  1WHE A;  2WG4 B;  5JW1 A;  4AQT A;  4BXW A;  5CKM A;  1IQM L;  5L2Z L;  2W2Q E;  2EI8 B;  1NFX B;  1XFE A;  1YUK B;  1EPJ A;  4RRW A;  2KL7 A;  1BF9 A;  4ZHA B;  2W26 B;  4CUF A;  2TGF A;  2FLR L;  4Y7A B;  1IQK L;  3HS6 A;  2FLG A;  1IVO C;  2P3U A;  2W2N E;  3IJE B;  3PGH A;  4NA9 L;  1COU A;  1LPG A;  4BXS A;  1URK A;  2Y80 B;  3Q3K B;  1XDT R;  1FF7 A;  5CKQ A;  3KK6 A;  1FAX L;  1TPG A;  2P93 L;  3RR3 A;  1NT0 A;  2BO2 A;  5CIS A;  2EI7 B;  5I46 L;  2I9A A;  2G00 L;  3LC5 B;  4XLW A;  4RUT A;  1YGC L;  2WYJ B;  1Z6C A;  4MMZ B;  4Y79 B;  4Z0K B;  1M1X B;  4E1G A;  1ATA A;  1IQH L;  4BTT A;  4D0F A;  2BOK L;  2XBY L;  1OB1 C;  4D90 A;  1KLO A;  1APO A;  2FD6 A;  2P3F N;  3U73 A;  1IOE L;  2J95 B;  1NFW B;  4X8U L;  4LMF A;  1SZB A;  1IP0 A;  1CVU A;  4BTU A;  4YT7 L;  3KQD L;  4RRY A;  1FJS L;  1CVW L;  2J38 B;  2K2T A;  3SW2 A;  2XC0 L;  4COX A;  1EMO A;  2RA0 L;  2P16 L;  4O02 B;  5COX A;  3BT1 A;  1L3Y A;  1J9C L;  3KCG L;  2PR3 B;  1HCG B;  1HJ7 A;  1IQJ L;  2WG3 C;  1EGF A;  1LPK A;  1APQ A;  3HS5 A;  4MMY B;  2P94 L;  2XC4 L;  3ASI A;  1HRF A;  3MDL A;  1PFX L;  2VVC K;  2MGP A;  1ZAQ A;  2W2M E;  2VH0 B;  2WPH E;  3ENS A;  5CKN A;  2OYU P;  2Y7Z B;  1AUT L;  5E8D A;  1CQE A;  4JYU L;  1WHF A;  2VWO L;  2Y7X B;  3KRK A;  3LAQ A;  4BDW A;  2PUQ L;  4JYV L;  2Y5F L;  2BQW A;  1NZI A;  1U8C B;  5KIR A;  1NQL B;  4X8S L;  1YO8 A;  1K36 A;  4BDX A;  3OLU A;  5JB8 E;  2P95 L;  1I0U A;  1JBU L;  1CCF A;  2FLB L;  3NTG A;  4NGA L;  1UZJ A;  1XKA L;  1IQF L;  5EGM B;  3TH3 L;  5IKV A;  2J34 B;  4YT6 L;  5IKR A;  4XBM A;  1U67 A;  4M11 A;  4Y6D B;  1KSN B;  4OTY A;  1G1R A;  2W2O E;  3LIW B;  1IJQ A;  1IOX A;  2J4I B;  2Y81 B;  1LMJ A;  2AYL A;  4D0E A;  3C9A C;  1IGX A;  2EI6 B;  1N1I A;  1MOX C;  1LPZ A;  1C5M F;  2WPJ E;  3KL6 B;  1Q4G A;  3F6U L;  3IIT B;  3KQB L;  4MMX B;  2UWP B;  2P3T A;  4TGF A;  1NFU B;  1ATB A;  4RRX A;  3N8W B;  1PRH A;  2VVV L;  1DIY A;  2WPI E;  2BQ7 A;  2BZ6 L;  1EQH A;  2D1J B;  1YUG A;  2BOH A;  1HZ8 A;  1EQG A;  2F9B L;  1MQ5 L;  1IQN L;  1CX2 A;  1KIG L;  3LC3 B;  3LN1 A;  3GCX E;  2WPK E;  5JBA E;  2P3F L;  1EPI A;  2Y5H L;  4OTJ A;  3CS7 L;  1PXX A;  1JV2 B;  1N7D A;  2WPM E;  3TZI A;  2W3I B;  1EPH A;  6COX A;  1A3P A;  2VH6 B;  2YGO A;  1V3X B;  3QMO A;  3SOQ A;  4JZD L;  1LQD A;  4Y76 B;  4X8T L;  3NJP C; 
#chains in the Genus database with same CATH topology
 2VRS A;  1FSB A;  5JVZ A;  3GCW E;  3OLT A;  3N8Y B;  1W8B L;  3HO5 A;  1KLI L;  1CEJ A;  3CEN L;  5JBB E;  2P28 B;  2Y82 B;  4ISI L;  2B7D L;  2UWL B;  4LOR A;  1L5G B;  1HT8 A;  2JKH L;  3BPS E;  4BTI A;  2NPR A;  2W2P E;  3BT2 A;  3KQC L;  1ATD A;  3HO3 A;  1G1T A;  1HRE A;  4RRZ A;  3V65 B;  1UZP A;  4GU4 A;  2XBX L;  2VWN L;  4Y7B B;  2KB9 A;  3N8W A;  2W86 A;  3N8Z A;  2WFX B;  4JZE L;  1JL9 A;  1GK5 A;  1KLJ L;  1Z6E L;  3EGF A;  1DQB A;  1G2L B;  2MGR A;  4O1Z A;  1G2M B;  1X7A L;  1HT5 A;  2Q1J B;  1HAE A;  1P9J A;  1IGZ A;  1V1I A;  3ELA L;  2BMG A;  3HPT A;  3TBD A;  2BSF A;  4ZAE B;  4CSY A;  5IKT A;  1F7E A;  1YUF A;  2UWO B;  2BOX A;  1G1Q A;  4RS0 A;  1IQI L;  3N8X A;  3QH0 A;  3TK6 B;  2VWL L;  1DVA L;  1B9W A;  5K0H B;  2XC5 L;  1RFN B;  4G1M B;  1EAI C;  1FAK L;  2P26 A;  4Y71 B;  1PGE A;  3SOV A;  1IQE L;  1UZQ A;  5IKQ A;  3TGF A;  3F1S B;  3P5B L;  4JZF L;  2BQ6 A;  3N8Y A;  4ZXX L;  3ZYG A;  4ZH8 B;  3HO4 A;  3ZYJ B;  1DDX A;  3FCS B;  2K2S B;  3V64 C;  3NT1 A;  4XL1 A;  3MQE A;  1TLE A;  4A94 C;  2KV4 A;  4C16 A;  1EPG A;  3M36 L;  2CJI B;  1F0S B;  2FZZ L;  1G1S A;  4CUD A;  2XBW L;  3CA7 A;  3LN0 A;  5F19 A;  5F1A A;  5JB9 E;  2J2U B;  3GIS X;  2VWM K;  3LTF B;  2OYE P;  3SOB B;  3M37 L;  2H9E L;  3HS7 A;  5L30 L;  3N8V A;  1F0R B;  3R05 A;  5JBC E;  5JVY A;  1WU1 B;  1FE2 A;  2VVU L;  1NFY B;  2MHP A;  2RNL A;  1IQG L;  3TK5 B;  4PH9 A;  3K9X A;  2Y38 A;  1F7M A;  2PHB B;  2RHP A;  3FFG L;  1W7X L;  1P0S L;  2VJ3 A;  3QCW A;  2Y5G L;  3KQE L;  2DDU A;  3POY A;  1XKB A;  4ISH L;  4M10 A;  1EMN A;  1FFM A;  5L2Y L;  1IQL L;  3Q7D A;  3CFW A;  5FDQ A;  4Z6A L;  2J94 B;  4YZU B;  2ADX A;  3U7U G;  1EZQ B;  2YGP A;  3ZYI B;  4NG9 L;  3NTB A;  4Z0L A;  2W3K B;  1TOZ A;  2GD4 A;  4A7I A;  3LTG D;  4X8V L;  3DEM A;  1ADX A;  4FM5 A;  4ZXY L;  1NPE B;  2M74 A;  1QFK L;  4CUE A;  1CCV A;  1O5D L;  1HX2 A;  1UZK A;  1EBV A;  1DX5 I;  2WYG B;  1PTH A;  3H5C B;  1K37 A;  2XBV L;  5KN5 C;  2I9B A;  1ATE A;  2BOU A;  3FBY A;  2WFT A;  2WPL E;  1HAF A;  1MQ6 L;  1WHE A;  2WZP P;  2WG4 B;  2H9E C;  5JW1 A;  4AQT A;  4BXW A;  1LMM A;  1IQM L;  5CKM A;  5L2Z L;  2W2Q E;  2EI8 B;  1NFX B;  1XFE A;  1YUK B;  1EPJ A;  4RRW A;  2KL7 A;  1BF9 A;  4ZHA B;  2W26 B;  4CUF A;  2TGF A;  2FLR L;  4Y7A B;  1IQK L;  3HS6 A;  2FLG A;  1IVO C;  2P3U A;  2HOX A;  2W2N E;  3IJE B;  3PGH A;  4NA9 L;  1COU A;  1LPG A;  4BXS A;  1URK A;  2Y80 B;  3Q3K B;  1XDT R;  1FF7 A;  5CKQ A;  3KK6 A;  1FAX L;  1V1H A;  1TPG A;  2P93 L;  3RR3 A;  1NT0 A;  2BO2 A;  5CIS A;  2EI7 B;  5I46 L;  2I9A A;  2G00 L;  3LC5 B;  2KNI A;  4XLW A;  4RUT A;  1YGC L;  2WYJ B;  1Z6C A;  4MMZ B;  4Y79 B;  4Z0K B;  1M1X B;  4E1G A;  1ATA A;  1IQH L;  4BTT A;  4D0F A;  2BOK L;  2XBY L;  1OB1 C;  4D90 A;  1KLO A;  1APO A;  2FD6 A;  2P3F N;  3U73 A;  1IOE L;  2J95 B;  1NFW B;  4X8U L;  4LMF A;  1SZB A;  1IP0 A;  1CVU A;  4BTU A;  3S6X A;  4YT7 L;  3KQD L;  4RRY A;  1FJS L;  1CVW L;  2J38 B;  2K2T A;  3SW2 A;  2XC0 L;  4COX A;  1EMO A;  2RA0 L;  2P16 L;  4O02 B;  5COX A;  3BT1 A;  1L3Y A;  1J9C L;  3KCG L;  2PR3 B;  1HCG B;  1HJ7 A;  1IQJ L;  2WG3 C;  1EGF A;  1LPK A;  1APQ A;  3HS5 A;  4MMY B;  2P94 L;  2XC4 L;  3ASI A;  1HRF A;  3MDL A;  1PFX L;  2VVC K;  2MGP A;  1ZAQ A;  2W2M E;  2VH0 B;  2WPH E;  2YGQ A;  3ENS A;  5CKN A;  2OYU P;  2Y7Z B;  1AUT L;  5E8D A;  1CQE A;  4JYU L;  1WHF A;  2VWO L;  1LK9 A;  2Y7X B;  3KRK A;  3LAQ A;  4BDW A;  2PUQ L;  4JYV L;  2Y5F L;  2BQW A;  1NZI A;  1U8C B;  5KIR A;  1NQL B;  4X8S L;  1YO8 A;  1K36 A;  2JJL A;  4BDX A;  3OLU A;  5JB8 E;  2P95 L;  1I0U A;  1JBU L;  1CCF A;  2FLB L;  3NTG A;  4NGA L;  1UZJ A;  1XKA L;  1IQF L;  5EGM B;  3TH3 L;  5IKV A;  2J34 B;  4YT6 L;  5IKR A;  4XBM A;  1U67 A;  4M11 A;  4Y6D B;  1KSN B;  4OTY A;  1G1R A;  2W2O E;  3LIW B;  2BT7 A;  1IJQ A;  1IOX A;  1QIU A;  2J4I B;  2Y81 B;  1LMJ A;  2AYL A;  4D0E A;  3C9A C;  1IGX A;  2EI6 B;  1N1I A;  1MOX C;  1LPZ A;  1C5M F;  2WPJ E;  3KL6 B;  1Q4G A;  3F6U L;  3IIT B;  3KQB L;  4MMX B;  2UWP B;  2P3T A;  4TGF A;  1NFU B;  1ATB A;  4RRX A;  4GU3 A;  3N8W B;  1PRH A;  2VVV L;  1DIY A;  2WPI E;  2BQ7 A;  2BZ6 L;  1EQH A;  2D1J B;  1YUG A;  2HOR A;  2BOH A;  1HZ8 A;  1EQG A;  2F9B L;  1MQ5 L;  1IQN L;  1KKE A;  1CX2 A;  1KIG L;  3LC3 B;  3LN1 A;  3GCX E;  2WPK E;  5JBA E;  2P3F L;  1EPI A;  2Y5H L;  4OTJ A;  3CS7 L;  2BT8 A;  1PXX A;  1JV2 B;  1N7D A;  2WPM E;  3TZI A;  2W3I B;  1EPH A;  6COX A;  1A3P A;  2VH6 B;  2YGO A;  1V3X B;  3QMO A;  3SOQ A;  4JZD L;  1LQD A;  4Y76 B;  4X8T L;  3NJP C; 
#chains in the Genus database with same CATH homology
 1FSB A;  5JVZ A;  3GCW E;  3OLT A;  3N8Y B;  1W8B L;  3HO5 A;  1KLI L;  1CEJ A;  3CEN L;  5JBB E;  2P28 B;  2Y82 B;  4ISI L;  2B7D L;  2UWL B;  4LOR A;  1L5G B;  1HT8 A;  2JKH L;  3BPS E;  4BTI A;  2NPR A;  2W2P E;  3BT2 A;  3KQC L;  1ATD A;  3HO3 A;  1G1T A;  1HRE A;  4RRZ A;  3V65 B;  1UZP A;  2XBX L;  2VWN L;  4Y7B B;  2KB9 A;  3N8W A;  2W86 A;  3N8Z A;  2WFX B;  4JZE L;  1JL9 A;  1GK5 A;  1KLJ L;  1Z6E L;  3EGF A;  1DQB A;  1G2L B;  2MGR A;  4O1Z A;  1G2M B;  1X7A L;  1HT5 A;  2Q1J B;  1HAE A;  1P9J A;  1IGZ A;  3ELA L;  2BMG A;  3HPT A;  3TBD A;  4ZAE B;  4CSY A;  5IKT A;  1F7E A;  1YUF A;  2UWO B;  2BOX A;  1G1Q A;  4RS0 A;  1IQI L;  3N8X A;  3QH0 A;  3TK6 B;  2VWL L;  1DVA L;  1B9W A;  5K0H B;  2XC5 L;  1RFN B;  4G1M B;  1EAI C;  1FAK L;  2P26 A;  4Y71 B;  1PGE A;  3SOV A;  1IQE L;  1UZQ A;  5IKQ A;  3TGF A;  3F1S B;  3P5B L;  4JZF L;  2BQ6 A;  3N8Y A;  4ZXX L;  3ZYG A;  4ZH8 B;  3HO4 A;  3ZYJ B;  1DDX A;  3FCS B;  2K2S B;  3V64 C;  3NT1 A;  4XL1 A;  3MQE A;  1TLE A;  4A94 C;  2KV4 A;  4C16 A;  1EPG A;  3M36 L;  2CJI B;  1F0S B;  2FZZ L;  1G1S A;  4CUD A;  2XBW L;  3CA7 A;  3LN0 A;  5F19 A;  5F1A A;  5JB9 E;  2J2U B;  3GIS X;  2VWM K;  3LTF B;  2OYE P;  3SOB B;  3M37 L;  2H9E L;  3HS7 A;  5L30 L;  3N8V A;  1F0R B;  3R05 A;  5JBC E;  5JVY A;  1WU1 B;  1FE2 A;  2VVU L;  1NFY B;  2MHP A;  2RNL A;  1IQG L;  3TK5 B;  4PH9 A;  3K9X A;  2Y38 A;  1F7M A;  2PHB B;  2RHP A;  3FFG L;  1W7X L;  1P0S L;  2VJ3 A;  3QCW A;  2Y5G L;  3KQE L;  2DDU A;  3POY A;  1XKB A;  4ISH L;  4M10 A;  1EMN A;  1FFM A;  5L2Y L;  1IQL L;  3Q7D A;  3CFW A;  5FDQ A;  4Z6A L;  2J94 B;  4YZU B;  2ADX A;  3U7U G;  1EZQ B;  2YGP A;  3ZYI B;  4NG9 L;  3NTB A;  4Z0L A;  2W3K B;  1TOZ A;  2GD4 A;  4A7I A;  3LTG D;  4X8V L;  3DEM A;  1ADX A;  4FM5 A;  4ZXY L;  1NPE B;  2M74 A;  1QFK L;  4CUE A;  1CCV A;  1O5D L;  1HX2 A;  1UZK A;  1EBV A;  1DX5 I;  2WYG B;  1PTH A;  3H5C B;  1K37 A;  2XBV L;  5KN5 C;  2I9B A;  1ATE A;  2BOU A;  3FBY A;  2WFT A;  2WPL E;  1HAF A;  1MQ6 L;  1WHE A;  2WZP P;  2WG4 B;  2H9E C;  5JW1 A;  4AQT A;  4BXW A;  1LMM A;  1IQM L;  5CKM A;  5L2Z L;  2W2Q E;  2EI8 B;  1NFX B;  1XFE A;  1YUK B;  1EPJ A;  4RRW A;  2KL7 A;  1BF9 A;  4ZHA B;  2W26 B;  4CUF A;  2TGF A;  2FLR L;  4Y7A B;  1IQK L;  3HS6 A;  2FLG A;  1IVO C;  2P3U A;  2W2N E;  3IJE B;  3PGH A;  4NA9 L;  1COU A;  1LPG A;  4BXS A;  1URK A;  2Y80 B;  3Q3K B;  1XDT R;  1FF7 A;  5CKQ A;  3KK6 A;  1FAX L;  1TPG A;  2P93 L;  3RR3 A;  1NT0 A;  2BO2 A;  5CIS A;  2EI7 B;  5I46 L;  2I9A A;  2G00 L;  3LC5 B;  2KNI A;  4XLW A;  4RUT A;  1YGC L;  2WYJ B;  1Z6C A;  4MMZ B;  4Y79 B;  4Z0K B;  1M1X B;  4E1G A;  1ATA A;  1IQH L;  4BTT A;  4D0F A;  2BOK L;  2XBY L;  1OB1 C;  4D90 A;  1KLO A;  1APO A;  2FD6 A;  2P3F N;  3U73 A;  1IOE L;  2J95 B;  1NFW B;  4X8U L;  4LMF A;  1SZB A;  1IP0 A;  1CVU A;  4BTU A;  3S6X A;  4YT7 L;  3KQD L;  4RRY A;  1FJS L;  1CVW L;  2J38 B;  2K2T A;  3SW2 A;  2XC0 L;  4COX A;  1EMO A;  2RA0 L;  2P16 L;  4O02 B;  5COX A;  3BT1 A;  1L3Y A;  1J9C L;  3KCG L;  2PR3 B;  1HCG B;  1HJ7 A;  1IQJ L;  2WG3 C;  1EGF A;  1LPK A;  1APQ A;  3HS5 A;  4MMY B;  2P94 L;  2XC4 L;  3ASI A;  1HRF A;  3MDL A;  1PFX L;  2VVC K;  2MGP A;  1ZAQ A;  2W2M E;  2VH0 B;  2WPH E;  2YGQ A;  3ENS A;  5CKN A;  2OYU P;  2Y7Z B;  1AUT L;  5E8D A;  1CQE A;  4JYU L;  1WHF A;  2VWO L;  2Y7X B;  3KRK A;  3LAQ A;  4BDW A;  2PUQ L;  4JYV L;  2Y5F L;  2BQW A;  1NZI A;  1U8C B;  5KIR A;  1NQL B;  4X8S L;  1YO8 A;  1K36 A;  4BDX A;  3OLU A;  5JB8 E;  2P95 L;  1I0U A;  1JBU L;  1CCF A;  2FLB L;  3NTG A;  4NGA L;  1UZJ A;  1XKA L;  1IQF L;  5EGM B;  3TH3 L;  5IKV A;  2J34 B;  4YT6 L;  5IKR A;  4XBM A;  1U67 A;  4M11 A;  4Y6D B;  1KSN B;  4OTY A;  1G1R A;  2W2O E;  3LIW B;  1IJQ A;  1IOX A;  2J4I B;  2Y81 B;  1LMJ A;  2AYL A;  4D0E A;  3C9A C;  1IGX A;  2EI6 B;  1N1I A;  1MOX C;  1LPZ A;  1C5M F;  2WPJ E;  3KL6 B;  1Q4G A;  3F6U L;  3IIT B;  3KQB L;  4MMX B;  2UWP B;  2P3T A;  4TGF A;  1NFU B;  1ATB A;  4RRX A;  3N8W B;  1PRH A;  2VVV L;  1DIY A;  2WPI E;  2BQ7 A;  2BZ6 L;  1EQH A;  2D1J B;  1YUG A;  2BOH A;  1HZ8 A;  1EQG A;  2F9B L;  1MQ5 L;  1IQN L;  1CX2 A;  1KIG L;  3LC3 B;  3LN1 A;  3GCX E;  2WPK E;  5JBA E;  2P3F L;  1EPI A;  2Y5H L;  4OTJ A;  3CS7 L;  1PXX A;  1JV2 B;  1N7D A;  2WPM E;  3TZI A;  2W3I B;  1EPH A;  6COX A;  1A3P A;  2VH6 B;  2YGO A;  1V3X B;  3QMO A;  3SOQ A;  4JZD L;  1LQD A;  4Y76 B;  4X8T L;  3NJP C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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