1LQDA

Crystal structure of fxa in complex with 45.
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
53
structure length
53
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and Quantitative Structure-Activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Blood coagulation factor Xa
total genus 11
structure length 53
sequence length 53
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2002-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00008 EGF EGF-like domain
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1lqdA00
1KSNB 2BOXA 3N8VA 1F7EA 2TGFA 1IOEL 3KCGL 2Y80B 2Y7ZB 3NTBA 1YGCL 4RRZA 2WFXB 3KQBL 1IQEL 3ZYJB 3R05A 1IQLL 3TGFA 4ZAEB 3LAQA 4CUEA 2XBYL 3C9AC 2AYLA 4RUTA 4E1GA 5L30L 2MGRA 3NTGA 4ZXXL 3TK6B 1ATEA 1U67A 4C16A 1DX5I 1NQLB 2GD4A 5JB8E 2EI6B 1P0SL 1KLOA 2P3FL 4OTJA 4JYVL 2PHBB 4BXSA 2Y5GL 3CFWA 4ZXYL 1Z6CA 1RFNB 2W2OE 2OYUP 4ZHAB 1W8BL 1PRHA 3TK5B 1G1RA 3ENSA 2WYJB 1FFMA 3M36L 3ZYIB 1EBVA 3HS7A 2P3UA 4BTIA 1N7DA 3KQEL 5K0HB 3IITB 2FLRL 1U8CB 2Q1JB 3FCSB 2EI8B 2H9EL 1APQA 3SW2A 3HO4A 4BTUA 1QFKL 3SOBB 1WU1B 1SZBA 2WPIE 3FFGL 1LPKA 4BDWA 1JL9A 1JBUL 1CCFA 1IQML 1DIYA 3M37L 1KIGL 5CKQA 1UZQA 1IQIL 1DVAL 1IOXA 2WPLE 1HJ7A 2FLGA 1HAEA 1CCVA 1CQEA 1NFYB 2P16L 3ASIA 1G1TA 2M74A 3QMOA 4BXWA 3U7UG 2W2PE 1G1QA 1Z6EL 3HS6A 4FM5A 1I0UA 1PGEA 2I9BA 4Y71B 3RR3A 4O02B 1AUTL 2YGOA 2W2ME 1HZ8A 2I9AA 3K9XA 3NJPC 3SOQA 3MDLA 1L3YA 4MMYB 1WHEA 5CISA 3KK6A 4NGAL 2BQ6A 4YT7L 4Y7AB 1MQ5L 3GCXE 4JYUL 3BT2A 2W3IB 1NFUB 4D0FA 2WPKE 3FBYA 2DDUA 3DEMA 3ELAL 1EZQB 4YZUB 1IQNL 1XKBA 2J95B 3LN1A 1NZIA 3BT1A 3N8ZA 2P95L 5F19A 4COXA 1EMNA 1EPIA 2UWPB 2KV4A 2XBVL 3LTFB 1ATBA 1EAIC 2W2NE 3LIWB 1TOZA 2PR3B 2ADXA 5JB9E 3F1SB 2K2SB 1W7XL 1LPZA 3LC3B 3QH0A 2Y38A 1ATDA 2RNLA 2Y82B 4CUDA 1EPHA 4RRWA 4RRXA 2J34B 1IQKL 5F1AA 1NFXB 3LN0A 2WG3C 3BPSE 1CEJA 2W3KB 4XLWA 4NG9L 1N1IA 3IJEB 3EGFA 2BO2A 1EPJA 2BOHA 3N8YA 2FLBL 3Q7DA 3HO3A 1IJQA 2P93L 1HX2A 1COUA 2J94B 3NT1A 4A7IA 4PH9A 1A3PA 5FDQA 1EMOA 4Z0KB 3N8XA 2FZZL 5L2YL 1C5MF 3CENL 2Y5FL 1TPGA 1XFEA 2WG4B 4LORA 5CKNA 1HT8A 5JBAE 4Y7BB 1YUKB 2NPRA 2Y81B 5E8DA 4XBMA 2P28B 2P3TA 3PGHA 4Y76B 2BMGA 2VVVL 3H5CB 3V65B 5KN5C 2UWLB 2XC5L 3SOVA 3OLUA 2W86A 1IQGL 2BQWA 2VJ3A 3OLTA 2FD6A 4X8TL 3CA7A 4Y79B 1IQHL 2BOKL 4MMZB 1UZKA 1V3XB 2D1JB 3N8WA 3Q3KB 1FAKL 1HREA 1X7AL 5CKMA 4JZDL 4RRYA 4AQTA 2OYEP 1CVWL 1KLIL 1K36A 2VWMK 2WPME 2P26A 1P9JA 1GK5A 3KQCL 2Y5HL 1HT5A 1FE2A 1EGFA 3TH3L 4Z6AL 1PXXA 4TGFA 4LMFA 2JKHL 2CJIB 4X8VL 3LTGD 4ISIL 1YUFA 3LC5B 1TLEA 2KL7A 1NPEB 3GCWE 5I46L 5JW1A 1G1SA 3U73A 2Y7XB 2RHPA 5IKQA 1MOXC 4CUFA 2K2TA 1F7MA 2KB9A 4G1MB 3HPTA 1UZPA 6COXA 4XL1A 1FJSL 2XBXL 3KQDL 1WHFA 2VVCK 4D0EA 5L2ZL 5JVZA 1F0RB 1HCGB 2EI7B 2VWNL 4Y6DB 5IKVA 1CX2A 4O1ZA 3KRKA 5JBBE 1IP0A 5JBCE 1KLJL 4X8UL 1G2LB 2J2UB 2BZ6L 1EQHA 4ZH8B 1ZAQA 1M1XB 3HS5A 2VH0B 2YGPA 5EGMB 2WPHE 1IQFL 1HAFA 1APOA 1Q4GA 2W26B 4X8SL 4M10A 1NFWB 2XBWL 3P5BL 4BDXA 4YT6L 4CSYA 2J38B 1OB1C 3F6UL 2F9BL 2B7DL 5IKTA 1HRFA 1EQGA 1IQJL 1FF7A 2P3FN 3HO5A 1NT0A 5KIRA 1XDTR 2P94L 1FSBA 3MQEA 2UWOB 3N8YB 2WFTA 4BTTA 2VWOL 2VWLL 1YUGA 2PUQL 4OTYA 1IGXA 1LPGA 3KL6B 1ATAA 1FAXL 2XC4L 4ISHL 3TZIA 1XKAL 5JVYA 2WPJE 2VH6B 4JZEL 1BF9A 2G00L 5IKRA 2MHPA 4RS0A 4NA9L 2BOUA 2W2QE 1O5DL 2WYGB 1LMJA 3V64C 1URKA 4Z0LA 2VVUL 1DQBA 1IVOC 3CS7L 3QCWA 3POYA 2XC0L 1G2MB 1ADXA 1LQDA 1IGZA 4MMXB 1JV2B 4M11A 1L5GB 3N8WB 2J4IB 1K37A 1PTHA 2RA0L 1DDXA 3TBDA 1EPGA 1MQ6L 3GISX 1F0SB 2MGPA 1J9CL 1B9WA 4D90A 2BQ7A 1CVUA 1UZJA 3ZYGA 4JZFL 5COXA 1PFXL 1YO8A
chains in the Genus database with same CATH superfamily
1KSNB 2BOXA 3N8VA 1F7EA 2TGFA 1IOEL 3KCGL 2Y80B 2Y7ZB 3NTBA 1YGCL 4RRZA 2WFXB 3KQBL 1IQEL 3ZYJB 3R05A 1IQLL 3TGFA 4ZAEB 3LAQA 4CUEA 2XBYL 3C9AC 2AYLA 4RUTA 4E1GA 5L30L 2MGRA 3NTGA 4ZXXL 3TK6B 1ATEA 1U67A 4C16A 1DX5I 1V1IA 1NQLB 2GD4A 5JB8E 2EI6B 1P0SL 1KLOA 2P3FL 4OTJA 4JYVL 2PHBB 4BXSA 2Y5GL 3CFWA 4ZXYL 1Z6CA 1RFNB 2W2OE 2OYUP 4ZHAB 1W8BL 1PRHA 3TK5B 1G1RA 3ENSA 2WYJB 1FFMA 3M36L 3ZYIB 1EBVA 3HS7A 2P3UA 4BTIA 4A94C 1N7DA 3KQEL 1LMMA 5K0HB 3IITB 2FLRL 1U8CB 2Q1JB 3FCSB 2EI8B 2H9EL 1APQA 3SW2A 3HO4A 4BTUA 1QFKL 3SOBB 1WU1B 1SZBA 2WPIE 2JJLA 3FFGL 1LPKA 4BDWA 1JL9A 1JBUL 1CCFA 1IQML 1DIYA 3M37L 1KIGL 5CKQA 1UZQA 1IQIL 2BT7A 1DVAL 1IOXA 2WPLE 1HJ7A 2FLGA 1HAEA 1CCVA 1CQEA 1NFYB 2P16L 2H9EC 3ASIA 1G1TA 2M74A 3QMOA 4BXWA 3U7UG 2W2PE 1G1QA 1Z6EL 3HS6A 4FM5A 1I0UA 1PGEA 2I9BA 4Y71B 3RR3A 4O02B 1AUTL 2YGOA 2W2ME 1HZ8A 2I9AA 3K9XA 3NJPC 3SOQA 3MDLA 1L3YA 4MMYB 1WHEA 5CISA 3KK6A 1QIUA 4NGAL 2BQ6A 4YT7L 2BT8A 4Y7AB 1MQ5L 3S6XA 3GCXE 4JYUL 3BT2A 2W3IB 4GU4A 1NFUB 4D0FA 2WPKE 3FBYA 2DDUA 3DEMA 3ELAL 1EZQB 4YZUB 1IQNL 1XKBA 2J95B 3LN1A 1NZIA 3BT1A 3N8ZA 2P95L 5F19A 4COXA 1EMNA 1EPIA 2UWPB 2KV4A 2XBVL 3LTFB 1ATBA 1EAIC 2W2NE 3LIWB 1TOZA 2PR3B 2ADXA 5JB9E 3F1SB 2K2SB 1W7XL 1LPZA 3LC3B 3QH0A 2Y38A 1ATDA 2RNLA 2Y82B 4CUDA 1EPHA 4RRWA 4RRXA 2J34B 1IQKL 5F1AA 1NFXB 2HORA 3LN0A 2WG3C 3BPSE 1CEJA 2W3KB 4XLWA 4NG9L 1N1IA 3IJEB 3EGFA 2BO2A 1EPJA 2BOHA 2FLBL 3N8YA 3Q7DA 3HO3A 1IJQA 2P93L 1HX2A 1COUA 2J94B 3NT1A 4A7IA 4PH9A 1A3PA 5FDQA 1EMOA 4Z0KB 3N8XA 2FZZL 5L2YL 1C5MF 3CENL 2Y5FL 1TPGA 1XFEA 2WG4B 4LORA 5CKNA 1HT8A 5JBAE 4Y7BB 1YUKB 2NPRA 2Y81B 5E8DA 4XBMA 2P28B 2P3TA 3PGHA 4Y76B 2BMGA 2VVVL 3H5CB 3V65B 5KN5C 1V1HA 2UWLB 2XC5L 3SOVA 3OLUA 2W86A 1IQGL 2BQWA 2VJ3A 3OLTA 2FD6A 4X8TL 3CA7A 4Y79B 1IQHL 2BOKL 4MMZB 1UZKA 1V3XB 2D1JB 3N8WA 3Q3KB 1FAKL 1HREA 1X7AL 5CKMA 4JZDL 4RRYA 4AQTA 2OYEP 1CVWL 1KLIL 1K36A 2VWMK 2WPME 2P26A 1P9JA 1GK5A 3KQCL 2Y5HL 1HT5A 1FE2A 1EGFA 3TH3L 4Z6AL 1PXXA 4TGFA 4LMFA 2JKHL 2CJIB 4X8VL 3LTGD 4ISIL 1YUFA 3LC5B 1TLEA 2KNIA 2KL7A 1NPEB 3GCWE 5I46L 5JW1A 1G1SA 3U73A 2Y7XB 2RHPA 5IKQA 1MOXC 4CUFA 2K2TA 1F7MA 2KB9A 4G1MB 3HPTA 1UZPA 6COXA 4XL1A 1FJSL 2XBXL 3KQDL 1WHFA 2VVCK 4D0EA 5L2ZL 5JVZA 1F0RB 1HCGB 2EI7B 2VWNL 4Y6DB 5IKVA 1CX2A 4O1ZA 3KRKA 5JBBE 1IP0A 5JBCE 1KLJL 4X8UL 1G2LB 2J2UB 1KKEA 2BZ6L 1EQHA 4ZH8B 1ZAQA 1M1XB 3HS5A 2VH0B 2YGPA 5EGMB 2WPHE 1IQFL 1HAFA 1APOA 1Q4GA 2W26B 4X8SL 4M10A 2BSFA 1NFWB 2XBWL 3P5BL 4BDXA 4YT6L 4CSYA 2J38B 1OB1C 3F6UL 2F9BL 2B7DL 5IKTA 1HRFA 1EQGA 1IQJL 1FF7A 2P3FN 3HO5A 4GU3A 1NT0A 5KIRA 1XDTR 2P94L 1FSBA 3MQEA 2UWOB 3N8YB 2WFTA 4BTTA 2VWOL 2WZPP 2VWLL 1YUGA 2PUQL 4OTYA 1IGXA 1LPGA 3KL6B 1ATAA 1FAXL 2XC4L 4ISHL 3TZIA 1XKAL 5JVYA 2VRSA 1LK9A 2WPJE 2VH6B 4JZEL 1BF9A 2G00L 5IKRA 2MHPA 4RS0A 4NA9L 2BOUA 2W2QE 1O5DL 2WYGB 1LMJA 3V64C 1URKA 4Z0LA 2VVUL 1DQBA 1IVOC 3CS7L 2HOXA 3QCWA 3POYA 2XC0L 1G2MB 1ADXA 2YGQA 1LQDA 1IGZA 4MMXB 1JV2B 4M11A 1L5GB 3N8WB 2J4IB 1K37A 1PTHA 2RA0L 1DDXA 3TBDA 1EPGA 1MQ6L 3GISX 1F0SB 2MGPA 1J9CL 1B9WA 4D90A 2BQ7A 1CVUA 1UZJA 3ZYGA 4JZFL 5COXA 1PFXL 1YO8A
chains in the Genus database with same CATH topology
1KSNB 2BOXA 3N8VA 1F7EA 2TGFA 1IOEL 3KCGL 2Y80B 2Y7ZB 3NTBA 1YGCL 4RRZA 2WFXB 3KQBL 1IQEL 3ZYJB 3R05A 1IQLL 3TGFA 4ZAEB 3LAQA 4CUEA 2XBYL 3C9AC 2AYLA 4RUTA 4E1GA 5L30L 2MGRA 3NTGA 4ZXXL 3TK6B 1ATEA 1U67A 4C16A 1DX5I 1NQLB 2GD4A 5JB8E 2EI6B 1P0SL 1KLOA 2P3FL 4OTJA 4JYVL 2PHBB 4BXSA 2Y5GL 3CFWA 4ZXYL 1Z6CA 1RFNB 2W2OE 2OYUP 4ZHAB 1W8BL 1PRHA 3TK5B 1G1RA 3ENSA 2WYJB 1FFMA 3M36L 3ZYIB 1EBVA 3HS7A 2P3UA 4BTIA 4A94C 1N7DA 3KQEL 1LMMA 5K0HB 3IITB 2FLRL 1U8CB 2Q1JB 3FCSB 2EI8B 2H9EL 1APQA 3SW2A 3HO4A 4BTUA 1QFKL 3SOBB 1WU1B 1SZBA 2WPIE 3FFGL 1LPKA 4BDWA 1JL9A 1JBUL 1CCFA 1IQML 1DIYA 3M37L 1KIGL 5CKQA 1UZQA 1IQIL 1DVAL 1IOXA 2WPLE 1HJ7A 2FLGA 1HAEA 1CCVA 1CQEA 1NFYB 2P16L 2H9EC 3ASIA 1G1TA 2M74A 3QMOA 4BXWA 3U7UG 2W2PE 1G1QA 1Z6EL 3HS6A 4FM5A 1I0UA 1PGEA 2I9BA 4Y71B 3RR3A 4O02B 1AUTL 2YGOA 2W2ME 1HZ8A 2I9AA 3K9XA 3NJPC 3SOQA 3MDLA 1L3YA 4MMYB 1WHEA 5CISA 3KK6A 4NGAL 2BQ6A 4YT7L 4Y7AB 1MQ5L 3S6XA 3GCXE 4JYUL 3BT2A 2W3IB 1NFUB 4D0FA 2WPKE 3FBYA 2DDUA 3DEMA 3ELAL 1EZQB 4YZUB 1IQNL 1XKBA 2J95B 3LN1A 1NZIA 3BT1A 3N8ZA 2P95L 5F19A 4COXA 1EMNA 1EPIA 2UWPB 2KV4A 2XBVL 3LTFB 1ATBA 1EAIC 2W2NE 3LIWB 1TOZA 2PR3B 2ADXA 5JB9E 3F1SB 2K2SB 1W7XL 1LPZA 3LC3B 3QH0A 2Y38A 1ATDA 2RNLA 2Y82B 4CUDA 1EPHA 4RRWA 4RRXA 2J34B 1IQKL 5F1AA 1NFXB 3LN0A 2WG3C 3BPSE 1CEJA 2W3KB 4XLWA 4NG9L 1N1IA 3IJEB 3EGFA 2BO2A 1EPJA 2BOHA 3N8YA 2FLBL 3Q7DA 3HO3A 1IJQA 2P93L 1HX2A 1COUA 2J94B 3NT1A 4A7IA 4PH9A 1A3PA 5FDQA 1EMOA 4Z0KB 3N8XA 2FZZL 5L2YL 1C5MF 3CENL 2Y5FL 1TPGA 1XFEA 2WG4B 4LORA 5CKNA 1HT8A 5JBAE 4Y7BB 1YUKB 2NPRA 2Y81B 5E8DA 4XBMA 2P28B 2P3TA 3PGHA 4Y76B 2BMGA 2VVVL 3H5CB 3V65B 5KN5C 2UWLB 2XC5L 3SOVA 3OLUA 2W86A 1IQGL 2BQWA 2VJ3A 3OLTA 2FD6A 4X8TL 3CA7A 4Y79B 1IQHL 2BOKL 4MMZB 1UZKA 1V3XB 2D1JB 3N8WA 3Q3KB 1FAKL 1HREA 1X7AL 5CKMA 4JZDL 4RRYA 4AQTA 2OYEP 1CVWL 1KLIL 1K36A 2VWMK 2WPME 2P26A 1P9JA 1GK5A 3KQCL 2Y5HL 1HT5A 1FE2A 1EGFA 3TH3L 4Z6AL 1PXXA 4TGFA 4LMFA 2JKHL 2CJIB 4X8VL 3LTGD 4ISIL 1YUFA 3LC5B 1TLEA 2KNIA 2KL7A 1NPEB 3GCWE 5I46L 5JW1A 1G1SA 3U73A 2Y7XB 2RHPA 5IKQA 1MOXC 4CUFA 2K2TA 1F7MA 2KB9A 4G1MB 3HPTA 1UZPA 6COXA 4XL1A 1FJSL 2XBXL 3KQDL 1WHFA 2VVCK 4D0EA 5L2ZL 5JVZA 1F0RB 1HCGB 2EI7B 2VWNL 4Y6DB 5IKVA 1CX2A 4O1ZA 3KRKA 5JBBE 1IP0A 5JBCE 1KLJL 4X8UL 1G2LB 2J2UB 2BZ6L 1EQHA 4ZH8B 1ZAQA 1M1XB 3HS5A 2VH0B 2YGPA 5EGMB 2WPHE 1IQFL 1HAFA 1APOA 1Q4GA 2W26B 4X8SL 4M10A 1NFWB 2XBWL 3P5BL 4BDXA 4YT6L 4CSYA 2J38B 1OB1C 3F6UL 2F9BL 2B7DL 5IKTA 1HRFA 1EQGA 1IQJL 1FF7A 2P3FN 3HO5A 1NT0A 5KIRA 1XDTR 2P94L 1FSBA 3MQEA 2UWOB 3N8YB 2WFTA 4BTTA 2VWOL 2WZPP 2VWLL 1YUGA 2PUQL 4OTYA 1IGXA 1LPGA 3KL6B 1ATAA 1FAXL 2XC4L 4ISHL 3TZIA 1XKAL 5JVYA 2WPJE 2VH6B 4JZEL 1BF9A 2G00L 5IKRA 2MHPA 4RS0A 4NA9L 2BOUA 2W2QE 1O5DL 2WYGB 1LMJA 3V64C 1URKA 4Z0LA 2VVUL 1DQBA 1IVOC 3CS7L 3QCWA 3POYA 2XC0L 1G2MB 1ADXA 2YGQA 1LQDA 1IGZA 4MMXB 1JV2B 4M11A 1L5GB 3N8WB 2J4IB 1K37A 1PTHA 2RA0L 1DDXA 3TBDA 1EPGA 1MQ6L 3GISX 1F0SB 2MGPA 1J9CL 1B9WA 4D90A 2BQ7A 1CVUA 1UZJA 3ZYGA 4JZFL 5COXA 1PFXL 1YO8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KSN B;  2BOX A;  3N8V A;  1F7E A;  2TGF A;  1IOE L;  3KCG L;  2Y80 B;  2Y7Z B;  3NTB A;  1YGC L;  4RRZ A;  2WFX B;  3KQB L;  1IQE L;  3ZYJ B;  3R05 A;  1IQL L;  3TGF A;  4ZAE B;  3LAQ A;  4CUE A;  2XBY L;  3C9A C;  2AYL A;  4RUT A;  4E1G A;  5L30 L;  2MGR A;  3NTG A;  4ZXX L;  3TK6 B;  1ATE A;  1U67 A;  4C16 A;  1DX5 I;  1NQL B;  2GD4 A;  5JB8 E;  2EI6 B;  1P0S L;  1KLO A;  2P3F L;  4OTJ A;  4JYV L;  2PHB B;  4BXS A;  2Y5G L;  3CFW A;  4ZXY L;  1Z6C A;  1RFN B;  2W2O E;  2OYU P;  4ZHA B;  1W8B L;  1PRH A;  3TK5 B;  1G1R A;  3ENS A;  2WYJ B;  1FFM A;  3M36 L;  3ZYI B;  1EBV A;  3HS7 A;  2P3U A;  4BTI A;  1N7D A;  3KQE L;  5K0H B;  3IIT B;  2FLR L;  1U8C B;  2Q1J B;  3FCS B;  2EI8 B;  2H9E L;  1APQ A;  3SW2 A;  3HO4 A;  4BTU A;  1QFK L;  3SOB B;  1WU1 B;  1SZB A;  2WPI E;  3FFG L;  1LPK A;  4BDW A;  1JL9 A;  1JBU L;  1CCF A;  1IQM L;  1DIY A;  3M37 L;  1KIG L;  5CKQ A;  1UZQ A;  1IQI L;  1DVA L;  1IOX A;  2WPL E;  1HJ7 A;  2FLG A;  1HAE A;  1CCV A;  1CQE A;  1NFY B;  2P16 L;  3ASI A;  1G1T A;  2M74 A;  3QMO A;  4BXW A;  3U7U G;  2W2P E;  1G1Q A;  1Z6E L;  3HS6 A;  4FM5 A;  1I0U A;  1PGE A;  2I9B A;  4Y71 B;  3RR3 A;  4O02 B;  1AUT L;  2YGO A;  2W2M E;  1HZ8 A;  2I9A A;  3K9X A;  3NJP C;  3SOQ A;  3MDL A;  1L3Y A;  4MMY B;  1WHE A;  5CIS A;  3KK6 A;  4NGA L;  2BQ6 A;  4YT7 L;  4Y7A B;  1MQ5 L;  3GCX E;  4JYU L;  3BT2 A;  2W3I B;  1NFU B;  4D0F A;  2WPK E;  3FBY A;  2DDU A;  3DEM A;  3ELA L;  1EZQ B;  4YZU B;  1IQN L;  1XKB A;  2J95 B;  3LN1 A;  1NZI A;  3BT1 A;  3N8Z A;  2P95 L;  5F19 A;  4COX A;  1EMN A;  1EPI A;  2UWP B;  2KV4 A;  2XBV L;  3LTF B;  1ATB A;  1EAI C;  2W2N E;  3LIW B;  1TOZ A;  2PR3 B;  2ADX A;  5JB9 E;  3F1S B;  2K2S B;  1W7X L;  1LPZ A;  3LC3 B;  3QH0 A;  2Y38 A;  1ATD A;  2RNL A;  2Y82 B;  4CUD A;  1EPH A;  4RRW A;  4RRX A;  2J34 B;  1IQK L;  5F1A A;  1NFX B;  3LN0 A;  2WG3 C;  3BPS E;  1CEJ A;  2W3K B;  4XLW A;  4NG9 L;  1N1I A;  3IJE B;  3EGF A;  2BO2 A;  1EPJ A;  2BOH A;  3N8Y A;  2FLB L;  3Q7D A;  3HO3 A;  1IJQ A;  2P93 L;  1HX2 A;  1COU A;  2J94 B;  3NT1 A;  4A7I A;  4PH9 A;  1A3P A;  5FDQ A;  1EMO A;  4Z0K B;  3N8X A;  2FZZ L;  5L2Y L;  1C5M F;  3CEN L;  2Y5F L;  1TPG A;  1XFE A;  2WG4 B;  4LOR A;  5CKN A;  1HT8 A;  5JBA E;  4Y7B B;  1YUK B;  2NPR A;  2Y81 B;  5E8D A;  4XBM A;  2P28 B;  2P3T A;  3PGH A;  4Y76 B;  2BMG A;  2VVV L;  3H5C B;  3V65 B;  5KN5 C;  2UWL B;  2XC5 L;  3SOV A;  3OLU A;  2W86 A;  1IQG L;  2BQW A;  2VJ3 A;  3OLT A;  2FD6 A;  4X8T L;  3CA7 A;  4Y79 B;  1IQH L;  2BOK L;  4MMZ B;  1UZK A;  1V3X B;  2D1J B;  3N8W A;  3Q3K B;  1FAK L;  1HRE A;  1X7A L;  5CKM A;  4JZD L;  4RRY A;  4AQT A;  2OYE P;  1CVW L;  1KLI L;  1K36 A;  2VWM K;  2WPM E;  2P26 A;  1P9J A;  1GK5 A;  3KQC L;  2Y5H L;  1HT5 A;  1FE2 A;  1EGF A;  3TH3 L;  4Z6A L;  1PXX A;  4TGF A;  4LMF A;  2JKH L;  2CJI B;  4X8V L;  3LTG D;  4ISI L;  1YUF A;  3LC5 B;  1TLE A;  2KL7 A;  1NPE B;  3GCW E;  5I46 L;  5JW1 A;  1G1S A;  3U73 A;  2Y7X B;  2RHP A;  5IKQ A;  1MOX C;  4CUF A;  2K2T A;  1F7M A;  2KB9 A;  4G1M B;  3HPT A;  1UZP A;  6COX A;  4XL1 A;  1FJS L;  2XBX L;  3KQD L;  1WHF A;  2VVC K;  4D0E A;  5L2Z L;  5JVZ A;  1F0R B;  1HCG B;  2EI7 B;  2VWN L;  4Y6D B;  5IKV A;  1CX2 A;  4O1Z A;  3KRK A;  5JBB E;  1IP0 A;  5JBC E;  1KLJ L;  4X8U L;  1G2L B;  2J2U B;  2BZ6 L;  1EQH A;  4ZH8 B;  1ZAQ A;  1M1X B;  3HS5 A;  2VH0 B;  2YGP A;  5EGM B;  2WPH E;  1IQF L;  1HAF A;  1APO A;  1Q4G A;  2W26 B;  4X8S L;  4M10 A;  1NFW B;  2XBW L;  3P5B L;  4BDX A;  4YT6 L;  4CSY A;  2J38 B;  1OB1 C;  3F6U L;  2F9B L;  2B7D L;  5IKT A;  1HRF A;  1EQG A;  1IQJ L;  1FF7 A;  2P3F N;  3HO5 A;  1NT0 A;  5KIR A;  1XDT R;  2P94 L;  1FSB A;  3MQE A;  2UWO B;  3N8Y B;  2WFT A;  4BTT A;  2VWO L;  2VWL L;  1YUG A;  2PUQ L;  4OTY A;  1IGX A;  1LPG A;  3KL6 B;  1ATA A;  1FAX L;  2XC4 L;  4ISH L;  3TZI A;  1XKA L;  5JVY A;  2WPJ E;  2VH6 B;  4JZE L;  1BF9 A;  2G00 L;  5IKR A;  2MHP A;  4RS0 A;  4NA9 L;  2BOU A;  2W2Q E;  1O5D L;  2WYG B;  1LMJ A;  3V64 C;  1URK A;  4Z0L A;  2VVU L;  1DQB A;  1IVO C;  3CS7 L;  3QCW A;  3POY A;  2XC0 L;  1G2M B;  1ADX A;  1LQD A;  1IGZ A;  4MMX B;  1JV2 B;  4M11 A;  1L5G B;  3N8W B;  2J4I B;  1K37 A;  1PTH A;  2RA0 L;  1DDX A;  3TBD A;  1EPG A;  1MQ6 L;  3GIS X;  1F0S B;  2MGP A;  1J9C L;  1B9W A;  4D90 A;  2BQ7 A;  1CVU A;  1UZJ A;  3ZYG A;  4JZF L;  5COX A;  1PFX L;  1YO8 A; 
#chains in the Genus database with same CATH topology
 1KSN B;  2BOX A;  3N8V A;  1F7E A;  2TGF A;  1IOE L;  3KCG L;  2Y80 B;  2Y7Z B;  3NTB A;  1YGC L;  4RRZ A;  2WFX B;  3KQB L;  1IQE L;  3ZYJ B;  3R05 A;  1IQL L;  3TGF A;  4ZAE B;  3LAQ A;  4CUE A;  2XBY L;  3C9A C;  2AYL A;  4RUT A;  4E1G A;  5L30 L;  2MGR A;  3NTG A;  4ZXX L;  3TK6 B;  1ATE A;  1U67 A;  4C16 A;  1DX5 I;  1V1I A;  1NQL B;  2GD4 A;  5JB8 E;  2EI6 B;  1P0S L;  1KLO A;  2P3F L;  4OTJ A;  4JYV L;  2PHB B;  4BXS A;  2Y5G L;  3CFW A;  4ZXY L;  1Z6C A;  1RFN B;  2W2O E;  2OYU P;  4ZHA B;  1W8B L;  1PRH A;  3TK5 B;  1G1R A;  3ENS A;  2WYJ B;  1FFM A;  3M36 L;  3ZYI B;  1EBV A;  3HS7 A;  2P3U A;  4BTI A;  4A94 C;  1N7D A;  3KQE L;  1LMM A;  5K0H B;  3IIT B;  2FLR L;  1U8C B;  2Q1J B;  3FCS B;  2EI8 B;  2H9E L;  1APQ A;  3SW2 A;  3HO4 A;  4BTU A;  1QFK L;  3SOB B;  1WU1 B;  1SZB A;  2WPI E;  2JJL A;  3FFG L;  1LPK A;  4BDW A;  1JL9 A;  1JBU L;  1CCF A;  1IQM L;  1DIY A;  3M37 L;  1KIG L;  5CKQ A;  1UZQ A;  1IQI L;  2BT7 A;  1DVA L;  1IOX A;  2WPL E;  1HJ7 A;  2FLG A;  1HAE A;  1CCV A;  1CQE A;  1NFY B;  2P16 L;  2H9E C;  3ASI A;  1G1T A;  2M74 A;  3QMO A;  4BXW A;  3U7U G;  2W2P E;  1G1Q A;  1Z6E L;  3HS6 A;  4FM5 A;  1I0U A;  1PGE A;  2I9B A;  4Y71 B;  3RR3 A;  4O02 B;  1AUT L;  2YGO A;  2W2M E;  1HZ8 A;  2I9A A;  3K9X A;  3NJP C;  3SOQ A;  3MDL A;  1L3Y A;  4MMY B;  1WHE A;  5CIS A;  3KK6 A;  1QIU A;  4NGA L;  2BQ6 A;  4YT7 L;  2BT8 A;  4Y7A B;  1MQ5 L;  3S6X A;  3GCX E;  4JYU L;  3BT2 A;  2W3I B;  4GU4 A;  1NFU B;  4D0F A;  2WPK E;  3FBY A;  2DDU A;  3DEM A;  3ELA L;  1EZQ B;  4YZU B;  1IQN L;  1XKB A;  2J95 B;  3LN1 A;  1NZI A;  3BT1 A;  3N8Z A;  2P95 L;  5F19 A;  4COX A;  1EMN A;  1EPI A;  2UWP B;  2KV4 A;  2XBV L;  3LTF B;  1ATB A;  1EAI C;  2W2N E;  3LIW B;  1TOZ A;  2PR3 B;  2ADX A;  5JB9 E;  3F1S B;  2K2S B;  1W7X L;  1LPZ A;  3LC3 B;  3QH0 A;  2Y38 A;  1ATD A;  2RNL A;  2Y82 B;  4CUD A;  1EPH A;  4RRW A;  4RRX A;  2J34 B;  1IQK L;  5F1A A;  1NFX B;  2HOR A;  3LN0 A;  2WG3 C;  3BPS E;  1CEJ A;  2W3K B;  4XLW A;  4NG9 L;  1N1I A;  3IJE B;  3EGF A;  2BO2 A;  1EPJ A;  2BOH A;  2FLB L;  3N8Y A;  3Q7D A;  3HO3 A;  1IJQ A;  2P93 L;  1HX2 A;  1COU A;  2J94 B;  3NT1 A;  4A7I A;  4PH9 A;  1A3P A;  5FDQ A;  1EMO A;  4Z0K B;  3N8X A;  2FZZ L;  5L2Y L;  1C5M F;  3CEN L;  2Y5F L;  1TPG A;  1XFE A;  2WG4 B;  4LOR A;  5CKN A;  1HT8 A;  5JBA E;  4Y7B B;  1YUK B;  2NPR A;  2Y81 B;  5E8D A;  4XBM A;  2P28 B;  2P3T A;  3PGH A;  4Y76 B;  2BMG A;  2VVV L;  3H5C B;  3V65 B;  5KN5 C;  1V1H A;  2UWL B;  2XC5 L;  3SOV A;  3OLU A;  2W86 A;  1IQG L;  2BQW A;  2VJ3 A;  3OLT A;  2FD6 A;  4X8T L;  3CA7 A;  4Y79 B;  1IQH L;  2BOK L;  4MMZ B;  1UZK A;  1V3X B;  2D1J B;  3N8W A;  3Q3K B;  1FAK L;  1HRE A;  1X7A L;  5CKM A;  4JZD L;  4RRY A;  4AQT A;  2OYE P;  1CVW L;  1KLI L;  1K36 A;  2VWM K;  2WPM E;  2P26 A;  1P9J A;  1GK5 A;  3KQC L;  2Y5H L;  1HT5 A;  1FE2 A;  1EGF A;  3TH3 L;  4Z6A L;  1PXX A;  4TGF A;  4LMF A;  2JKH L;  2CJI B;  4X8V L;  3LTG D;  4ISI L;  1YUF A;  3LC5 B;  1TLE A;  2KNI A;  2KL7 A;  1NPE B;  3GCW E;  5I46 L;  5JW1 A;  1G1S A;  3U73 A;  2Y7X B;  2RHP A;  5IKQ A;  1MOX C;  4CUF A;  2K2T A;  1F7M A;  2KB9 A;  4G1M B;  3HPT A;  1UZP A;  6COX A;  4XL1 A;  1FJS L;  2XBX L;  3KQD L;  1WHF A;  2VVC K;  4D0E A;  5L2Z L;  5JVZ A;  1F0R B;  1HCG B;  2EI7 B;  2VWN L;  4Y6D B;  5IKV A;  1CX2 A;  4O1Z A;  3KRK A;  5JBB E;  1IP0 A;  5JBC E;  1KLJ L;  4X8U L;  1G2L B;  2J2U B;  1KKE A;  2BZ6 L;  1EQH A;  4ZH8 B;  1ZAQ A;  1M1X B;  3HS5 A;  2VH0 B;  2YGP A;  5EGM B;  2WPH E;  1IQF L;  1HAF A;  1APO A;  1Q4G A;  2W26 B;  4X8S L;  4M10 A;  2BSF A;  1NFW B;  2XBW L;  3P5B L;  4BDX A;  4YT6 L;  4CSY A;  2J38 B;  1OB1 C;  3F6U L;  2F9B L;  2B7D L;  5IKT A;  1HRF A;  1EQG A;  1IQJ L;  1FF7 A;  2P3F N;  3HO5 A;  4GU3 A;  1NT0 A;  5KIR A;  1XDT R;  2P94 L;  1FSB A;  3MQE A;  2UWO B;  3N8Y B;  2WFT A;  4BTT A;  2VWO L;  2WZP P;  2VWL L;  1YUG A;  2PUQ L;  4OTY A;  1IGX A;  1LPG A;  3KL6 B;  1ATA A;  1FAX L;  2XC4 L;  4ISH L;  3TZI A;  1XKA L;  5JVY A;  2VRS A;  1LK9 A;  2WPJ E;  2VH6 B;  4JZE L;  1BF9 A;  2G00 L;  5IKR A;  2MHP A;  4RS0 A;  4NA9 L;  2BOU A;  2W2Q E;  1O5D L;  2WYG B;  1LMJ A;  3V64 C;  1URK A;  4Z0L A;  2VVU L;  1DQB A;  1IVO C;  3CS7 L;  2HOX A;  3QCW A;  3POY A;  2XC0 L;  1G2M B;  1ADX A;  2YGQ A;  1LQD A;  1IGZ A;  4MMX B;  1JV2 B;  4M11 A;  1L5G B;  3N8W B;  2J4I B;  1K37 A;  1PTH A;  2RA0 L;  1DDX A;  3TBD A;  1EPG A;  1MQ6 L;  3GIS X;  1F0S B;  2MGP A;  1J9C L;  1B9W A;  4D90 A;  2BQ7 A;  1CVU A;  1UZJ A;  3ZYG A;  4JZF L;  5COX A;  1PFX L;  1YO8 A; 
#chains in the Genus database with same CATH homology
 1KSN B;  2BOX A;  3N8V A;  1F7E A;  2TGF A;  1IOE L;  3KCG L;  2Y80 B;  2Y7Z B;  3NTB A;  1YGC L;  4RRZ A;  2WFX B;  3KQB L;  1IQE L;  3ZYJ B;  3R05 A;  1IQL L;  3TGF A;  4ZAE B;  3LAQ A;  4CUE A;  2XBY L;  3C9A C;  2AYL A;  4RUT A;  4E1G A;  5L30 L;  2MGR A;  3NTG A;  4ZXX L;  3TK6 B;  1ATE A;  1U67 A;  4C16 A;  1DX5 I;  1NQL B;  2GD4 A;  5JB8 E;  2EI6 B;  1P0S L;  1KLO A;  2P3F L;  4OTJ A;  4JYV L;  2PHB B;  4BXS A;  2Y5G L;  3CFW A;  4ZXY L;  1Z6C A;  1RFN B;  2W2O E;  2OYU P;  4ZHA B;  1W8B L;  1PRH A;  3TK5 B;  1G1R A;  3ENS A;  2WYJ B;  1FFM A;  3M36 L;  3ZYI B;  1EBV A;  3HS7 A;  2P3U A;  4BTI A;  4A94 C;  1N7D A;  3KQE L;  1LMM A;  5K0H B;  3IIT B;  2FLR L;  1U8C B;  2Q1J B;  3FCS B;  2EI8 B;  2H9E L;  1APQ A;  3SW2 A;  3HO4 A;  4BTU A;  1QFK L;  3SOB B;  1WU1 B;  1SZB A;  2WPI E;  3FFG L;  1LPK A;  4BDW A;  1JL9 A;  1JBU L;  1CCF A;  1IQM L;  1DIY A;  3M37 L;  1KIG L;  5CKQ A;  1UZQ A;  1IQI L;  1DVA L;  1IOX A;  2WPL E;  1HJ7 A;  2FLG A;  1HAE A;  1CCV A;  1CQE A;  1NFY B;  2P16 L;  2H9E C;  3ASI A;  1G1T A;  2M74 A;  3QMO A;  4BXW A;  3U7U G;  2W2P E;  1G1Q A;  1Z6E L;  3HS6 A;  4FM5 A;  1I0U A;  1PGE A;  2I9B A;  4Y71 B;  3RR3 A;  4O02 B;  1AUT L;  2YGO A;  2W2M E;  1HZ8 A;  2I9A A;  3K9X A;  3NJP C;  3SOQ A;  3MDL A;  1L3Y A;  4MMY B;  1WHE A;  5CIS A;  3KK6 A;  4NGA L;  2BQ6 A;  4YT7 L;  4Y7A B;  1MQ5 L;  3S6X A;  3GCX E;  4JYU L;  3BT2 A;  2W3I B;  1NFU B;  4D0F A;  2WPK E;  3FBY A;  2DDU A;  3DEM A;  3ELA L;  1EZQ B;  4YZU B;  1IQN L;  1XKB A;  2J95 B;  3LN1 A;  1NZI A;  3BT1 A;  3N8Z A;  2P95 L;  5F19 A;  4COX A;  1EMN A;  1EPI A;  2UWP B;  2KV4 A;  2XBV L;  3LTF B;  1ATB A;  1EAI C;  2W2N E;  3LIW B;  1TOZ A;  2PR3 B;  2ADX A;  5JB9 E;  3F1S B;  2K2S B;  1W7X L;  1LPZ A;  3LC3 B;  3QH0 A;  2Y38 A;  1ATD A;  2RNL A;  2Y82 B;  4CUD A;  1EPH A;  4RRW A;  4RRX A;  2J34 B;  1IQK L;  5F1A A;  1NFX B;  3LN0 A;  2WG3 C;  3BPS E;  1CEJ A;  2W3K B;  4XLW A;  4NG9 L;  1N1I A;  3IJE B;  3EGF A;  2BO2 A;  1EPJ A;  2BOH A;  3N8Y A;  2FLB L;  3Q7D A;  3HO3 A;  1IJQ A;  2P93 L;  1HX2 A;  1COU A;  2J94 B;  3NT1 A;  4A7I A;  4PH9 A;  1A3P A;  5FDQ A;  1EMO A;  4Z0K B;  3N8X A;  2FZZ L;  5L2Y L;  1C5M F;  3CEN L;  2Y5F L;  1TPG A;  1XFE A;  2WG4 B;  4LOR A;  5CKN A;  1HT8 A;  5JBA E;  4Y7B B;  1YUK B;  2NPR A;  2Y81 B;  5E8D A;  4XBM A;  2P28 B;  2P3T A;  3PGH A;  4Y76 B;  2BMG A;  2VVV L;  3H5C B;  3V65 B;  5KN5 C;  2UWL B;  2XC5 L;  3SOV A;  3OLU A;  2W86 A;  1IQG L;  2BQW A;  2VJ3 A;  3OLT A;  2FD6 A;  4X8T L;  3CA7 A;  4Y79 B;  1IQH L;  2BOK L;  4MMZ B;  1UZK A;  1V3X B;  2D1J B;  3N8W A;  3Q3K B;  1FAK L;  1HRE A;  1X7A L;  5CKM A;  4JZD L;  4RRY A;  4AQT A;  2OYE P;  1CVW L;  1KLI L;  1K36 A;  2VWM K;  2WPM E;  2P26 A;  1P9J A;  1GK5 A;  3KQC L;  2Y5H L;  1HT5 A;  1FE2 A;  1EGF A;  3TH3 L;  4Z6A L;  1PXX A;  4TGF A;  4LMF A;  2JKH L;  2CJI B;  4X8V L;  3LTG D;  4ISI L;  1YUF A;  3LC5 B;  1TLE A;  2KNI A;  2KL7 A;  1NPE B;  3GCW E;  5I46 L;  5JW1 A;  1G1S A;  3U73 A;  2Y7X B;  2RHP A;  5IKQ A;  1MOX C;  4CUF A;  2K2T A;  1F7M A;  2KB9 A;  4G1M B;  3HPT A;  1UZP A;  6COX A;  4XL1 A;  1FJS L;  2XBX L;  3KQD L;  1WHF A;  2VVC K;  4D0E A;  5L2Z L;  5JVZ A;  1F0R B;  1HCG B;  2EI7 B;  2VWN L;  4Y6D B;  5IKV A;  1CX2 A;  4O1Z A;  3KRK A;  5JBB E;  1IP0 A;  5JBC E;  1KLJ L;  4X8U L;  1G2L B;  2J2U B;  2BZ6 L;  1EQH A;  4ZH8 B;  1ZAQ A;  1M1X B;  3HS5 A;  2VH0 B;  2YGP A;  5EGM B;  2WPH E;  1IQF L;  1HAF A;  1APO A;  1Q4G A;  2W26 B;  4X8S L;  4M10 A;  1NFW B;  2XBW L;  3P5B L;  4BDX A;  4YT6 L;  4CSY A;  2J38 B;  1OB1 C;  3F6U L;  2F9B L;  2B7D L;  5IKT A;  1HRF A;  1EQG A;  1IQJ L;  1FF7 A;  2P3F N;  3HO5 A;  1NT0 A;  5KIR A;  1XDT R;  2P94 L;  1FSB A;  3MQE A;  2UWO B;  3N8Y B;  2WFT A;  4BTT A;  2VWO L;  2WZP P;  2VWL L;  1YUG A;  2PUQ L;  4OTY A;  1IGX A;  1LPG A;  3KL6 B;  1ATA A;  1FAX L;  2XC4 L;  4ISH L;  3TZI A;  1XKA L;  5JVY A;  2WPJ E;  2VH6 B;  4JZE L;  1BF9 A;  2G00 L;  5IKR A;  2MHP A;  4RS0 A;  4NA9 L;  2BOU A;  2W2Q E;  1O5D L;  2WYG B;  1LMJ A;  3V64 C;  1URK A;  4Z0L A;  2VVU L;  1DQB A;  1IVO C;  3CS7 L;  3QCW A;  3POY A;  2XC0 L;  1G2M B;  1ADX A;  2YGQ A;  1LQD A;  1IGZ A;  4MMX B;  1JV2 B;  4M11 A;  1L5G B;  3N8W B;  2J4I B;  1K37 A;  1PTH A;  2RA0 L;  1DDX A;  3TBD A;  1EPG A;  1MQ6 L;  3GIS X;  1F0S B;  2MGP A;  1J9C L;  1B9W A;  4D90 A;  2BQ7 A;  1CVU A;  1UZJ A;  3ZYG A;  4JZF L;  5COX A;  1PFX L;  1YO8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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