1NFUB

Crystal structure of human coagulation factor xa complexed with rpr132747
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular structures of human Factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords COAGULATION FACTOR XA, HEAVY CHAIN
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2002-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00008 EGF EGF-like domain
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1nfuB00
1QFKL 2BOUA 1V3XB 2VWNL 3Q7DA 1LQDA 3ELAL 3LN0A 2VJ3A 2MGRA 3BPSE 1KIGL 4Y71B 3U73A 4NA9L 4MMZB 1ZAQA 1PTHA 1EPJA 2Y5HL 1O5DL 4BXSA 4BXWA 2B7DL 1DVAL 1NFYB 2VWOL 1G2LB 4Z0KB 3TZIA 4YZUB 1EPGA 1M1XB 5FDQA 1EAIC 1YO8A 2XBYL 3Q3KB 1FFMA 5COXA 1W7XL 1YUKB 3F1SB 1TLEA 4ZXYL 3PGHA 2MGPA 4RUTA 1JV2B 1SZBA 1TPGA 1N1IA 3LTGD 2Y80B 4Y6DB 4CSYA 1IQLL 2EI6B 2BOKL 1ADXA 3ZYJB 2P3TA 2Y5GL 5L30L 3N8VA 5L2YL 4D0FA 3MDLA 4Z6AL 3N8XA 4X8UL 1X7AL 1DIYA 1EMNA 2DDUA 2Y82B 2W2QE 2W2OE 3IITB 1NFWB 1IOXA 1P9JA 4Y7AB 4JZFL 3NTGA 1F0RB 3BT1A 3F6UL 4MMXB 2FD6A 1KLIL 1IQJL 3SOQA 2I9BA 4JZDL 1DQBA 4A7IA 1U8CB 1NQLB 1IVOC 1EPIA 5JB9E 4FM5A 2EI7B 1IP0A 3TK6B 2FLRL 2P3FN 4LMFA 4RS0A 5IKQA 1UZJA 2J95B 3LC5B 5KIRA 4ZAEB 5JB8E 3QH0A 3ENSA 1APQA 2F9BL 1IGXA 2VVUL 3LC3B 1I0UA 4BTIA 1YUFA 2Y7XB 1GK5A 1WHEA 4OTYA 3SW2A 2W3KB 2FZZL 1CCVA 1IQEL 3FCSB 2BQ7A 2Y5FL 1MQ5L 5CKMA 4PH9A 2Y81B 5JBCE 1LPGA 3V64C 1BF9A 2PUQL 1KSNB 1XDTR 4RRYA 1HCGB 1EPHA 1J9CL 2VWMK 2K2TA 1LPKA 2YGOA 3M36L 5CKQA 5IKVA 5KN5C 2KV4A 1NFXB 3NTBA 3MQEA 1MOXC 2WPIE 1TOZA 4ZHAB 1FSBA 2P3FL 3LIWB 2XBVL 2G00L 1JL9A 2WYGB 1C5MF 2J38B 4D90A 1RFNB 1HAFA 4OTJA 1U67A 1CQEA 2VH0B 2W2NE 2P95L 3V65B 4M11A 1WHFA 3N8YB 1EMOA 2PHBB 1LPZA 2VWLL 1IQFL 3GCXE 1HRFA 2KL7A 2XC5L 3CFWA 4XLWA 1ATDA 2UWLB 4Y79B 1IQGL 4BDWA 2P16L 4XL1A 1Q4GA 4C16A 2MHPA 3ZYIB 1HREA 1NZIA 1JBUL 2EI8B 2P26A 3N8WA 4O1ZA 3RR3A 3ASIA 2WFXB 1G1QA 2BOXA 3KQEL 6COXA 1FF7A 3U7UG 1G1TA 5JVYA 3TH3L 2GD4A 2WPKE 3GISX 2WPLE 5JBAE 1DX5I 5JVZA 1XFEA 3KK6A 1IOEL 4COXA 2UWPB 2BMGA 1CCFA 2W26B 1N7DA 3KQCL 2J2UB 1XKAL 4X8SL 3IJEB 4XBMA 1IQHL 1NT0A 3GCWE 3CS7L 1HZ8A 4BTTA 1EQHA 1XKBA 3HO3A 5JBBE 3ZYGA 1YUGA 1FAXL 4CUEA 2Y38A 1L3YA 5JW1A 4CUFA 1UZQA 2WPJE 3N8WB 4G1MB 2Q1JB 1IJQA 3LAQA 4D0EA 4E1GA 3N8YA 2OYEP 4RRXA 1EZQB 4ISHL 1PGEA 2P93L 2K2SB 3M37L 2JKHL 3SOVA 3KRKA 4ZH8B 2VH6B 3C9AC 3NJPC 2M74A 1HT5A 2P3UA 2VVCK 3KQBL 4RRZA 1UZKA 5L2ZL 1G2MB 2FLBL 3HS6A 2W3IB 4M10A 4X8VL 2BQ6A 3HO4A 4BTUA 3EGFA 3KQDL 2WG4B 2NPRA 1NPEB 3R05A 5EGMB 4RRWA 2AYLA 5IKTA 2CJIB 1K36A 1ATBA 5IKRA 1HX2A 3BT2A 1MQ6L 3DEMA 2J34B 1PRHA 4NGAL 2RA0L 2W2ME 2H9EL 2BO2A 3NT1A 2P94L 2BQWA 3H5CB 2YGPA 1COUA 2Y7ZB 3HS7A 4JYUL 2BOHA 1CEJA 3KL6B 1L5GB 4MMYB 4Y7BB 1B9WA 4TGFA 1AUTL 5K0HB 2ADXA 2BZ6L 1HJ7A 1Z6CA 4ZXXL 3CENL 4CUDA 3QMOA 2UWOB 1LMJA 2WG3C 1IQIL 3TGFA 2WYJB 2OYUP 1F0SB 4Z0LA 1HAEA 3OLTA 4YT6L 3LTFB 5CKNA 1FAKL 3FFGL 3HS5A 1P0SL 2XBXL 4Y76B 1EBVA 1G1SA 4JYVL 1F7MA 3N8ZA 2WPHE 1CVUA 5E8DA 2J4IB 2KB9A 1F7EA 1IQML 4NG9L 1CX2A 1URKA 3LN1A 4ISIL 4LORA 2PR3B 2FLGA 3K9XA 4BDXA 5F1AA 2XBWL 1KLJL 3POYA 4YT7L 2W86A 2D1JB 3QCWA 1FE2A 4JZEL 5F19A 3FBYA 1IQKL 3TBDA 2XC0L 1DDXA 4AQTA 3SOBB 1K37A 2W2PE 1WU1B 1EGFA 3TK5B 5I46L 1UZPA 1HT8A 2WPME 1IGZA 3CA7A 2J94B 1IQNL 2RNLA 4X8TL 4O02B 2XC4L 1OB1C 2P28B 3OLUA 5CISA 1APOA 1G1RA 2TGFA 1CVWL 1PXXA 1YGCL 1Z6EL 1ATEA 1KLOA 3KCGL 2WFTA 1NFUB 2I9AA 2RHPA 3HO5A 1ATAA 1EQGA 2VVVL 3P5BL 1A3PA 1FJSL 1PFXL 3HPTA 1W8BL
chains in the Genus database with same CATH superfamily
1QFKL 2BOUA 1V3XB 2VWNL 3Q7DA 1LQDA 3ELAL 3LN0A 2VJ3A 2MGRA 3BPSE 1KIGL 4Y71B 3U73A 4NA9L 4MMZB 1ZAQA 1PTHA 1EPJA 2Y5HL 1KKEA 1O5DL 4BXSA 4BXWA 2B7DL 1DVAL 1NFYB 2VWOL 1G2LB 4Z0KB 3TZIA 4YZUB 1EPGA 1M1XB 5FDQA 1EAIC 1YO8A 2XBYL 3Q3KB 1FFMA 5COXA 1W7XL 1YUKB 3F1SB 1TLEA 4ZXYL 3PGHA 2MGPA 4RUTA 1JV2B 1SZBA 2KNIA 1TPGA 1N1IA 3LTGD 2Y80B 4Y6DB 4CSYA 1IQLL 2EI6B 2BOKL 1ADXA 3ZYJB 2P3TA 2Y5GL 5L30L 3N8VA 5L2YL 4D0FA 3MDLA 4Z6AL 3N8XA 4X8UL 1X7AL 1DIYA 1EMNA 2DDUA 2Y82B 2W2QE 2W2OE 3IITB 1NFWB 1IOXA 1P9JA 4Y7AB 4JZFL 3NTGA 1F0RB 3BT1A 3F6UL 4MMXB 2FD6A 1KLIL 1IQJL 3SOQA 2I9BA 4JZDL 1DQBA 4A7IA 1U8CB 1NQLB 1IVOC 1EPIA 5JB9E 4FM5A 2EI7B 2HOXA 1IP0A 3TK6B 2FLRL 2P3FN 4LMFA 4RS0A 5IKQA 1UZJA 2J95B 3LC5B 5KIRA 4ZAEB 5JB8E 3QH0A 3ENSA 1V1IA 1APQA 2F9BL 1IGXA 2VVUL 3LC3B 1I0UA 4BTIA 1YUFA 2Y7XB 4A94C 1GK5A 1WHEA 4OTYA 3SW2A 2W3KB 2FZZL 1CCVA 1IQEL 3FCSB 2BQ7A 2Y5FL 1MQ5L 2WZPP 5CKMA 4PH9A 2Y81B 5JBCE 1LPGA 3V64C 1BF9A 2PUQL 1KSNB 1XDTR 4RRYA 1HCGB 1EPHA 1J9CL 2VWMK 2K2TA 1LPKA 2YGOA 3M36L 5CKQA 5IKVA 5KN5C 2KV4A 1NFXB 3NTBA 3MQEA 1MOXC 2WPIE 1TOZA 4ZHAB 1FSBA 2P3FL 3LIWB 2XBVL 2G00L 1JL9A 2WYGB 1C5MF 2J38B 4D90A 1RFNB 1HAFA 4OTJA 1U67A 1CQEA 2VH0B 2W2NE 2P95L 3V65B 4M11A 1WHFA 3N8YB 1EMOA 2PHBB 1LPZA 2VWLL 1IQFL 3GCXE 1HRFA 2KL7A 2XC5L 3CFWA 4XLWA 1ATDA 2UWLB 4Y79B 1IQGL 4BDWA 2P16L 4XL1A 1Q4GA 4C16A 2MHPA 3ZYIB 1HREA 1NZIA 1JBUL 2EI8B 2P26A 3N8WA 4O1ZA 3RR3A 3ASIA 2WFXB 1G1QA 2BOXA 3KQEL 6COXA 1FF7A 3U7UG 1G1TA 5JVYA 3TH3L 2GD4A 2WPKE 3GISX 2WPLE 5JBAE 1DX5I 5JVZA 1XFEA 3KK6A 1IOEL 4COXA 2UWPB 2BMGA 1CCFA 2W26B 1N7DA 3KQCL 2J2UB 1XKAL 4X8SL 3IJEB 4XBMA 1IQHL 1NT0A 3GCWE 3CS7L 1HZ8A 4BTTA 1EQHA 1XKBA 3HO3A 5JBBE 3ZYGA 1YUGA 2HORA 1FAXL 4CUEA 2Y38A 1L3YA 5JW1A 2JJLA 4CUFA 1UZQA 2WPJE 3N8WB 4G1MB 2Q1JB 1IJQA 3LAQA 4D0EA 4E1GA 3N8YA 2OYEP 4RRXA 1EZQB 4ISHL 1PGEA 2P93L 2K2SB 3M37L 2JKHL 3SOVA 3KRKA 4ZH8B 2VH6B 3C9AC 3NJPC 2M74A 1HT5A 2P3UA 2VVCK 3KQBL 4RRZA 1UZKA 5L2ZL 1G2MB 2FLBL 3HS6A 2BT7A 2W3IB 4M10A 4X8VL 2BQ6A 3HO4A 4BTUA 3EGFA 1QIUA 3KQDL 2WG4B 2NPRA 1NPEB 3R05A 5EGMB 4RRWA 2AYLA 5IKTA 2CJIB 1K36A 1ATBA 5IKRA 1HX2A 3BT2A 1MQ6L 3DEMA 2J34B 1PRHA 4NGAL 2BT8A 2RA0L 2W2ME 2H9EL 2BO2A 3NT1A 2P94L 2BQWA 3H5CB 2YGPA 1COUA 2Y7ZB 3HS7A 4JYUL 2BOHA 1CEJA 3KL6B 1L5GB 4MMYB 4Y7BB 1B9WA 4TGFA 2VRSA 1AUTL 5K0HB 2ADXA 2BZ6L 1HJ7A 1Z6CA 4ZXXL 1LK9A 3CENL 4CUDA 3QMOA 2UWOB 4GU3A 1LMJA 2WG3C 1IQIL 3TGFA 2WYJB 2OYUP 1F0SB 4Z0LA 1HAEA 3OLTA 4YT6L 3LTFB 5CKNA 2BSFA 1FAKL 3FFGL 3HS5A 2YGQA 1P0SL 2XBXL 4Y76B 1EBVA 1G1SA 4JYVL 1F7MA 3S6XA 3N8ZA 2WPHE 1CVUA 5E8DA 2J4IB 2KB9A 1F7EA 1IQML 4NG9L 1CX2A 1URKA 3LN1A 4ISIL 4LORA 2PR3B 2FLGA 3K9XA 4BDXA 5F1AA 2XBWL 1KLJL 3POYA 4YT7L 2W86A 2D1JB 2H9EC 3QCWA 1FE2A 4JZEL 5F19A 3FBYA 1IQKL 3TBDA 2XC0L 1DDXA 4AQTA 3SOBB 1K37A 2W2PE 1WU1B 1EGFA 3TK5B 5I46L 1LMMA 1UZPA 1HT8A 2WPME 1IGZA 3CA7A 2J94B 1IQNL 2RNLA 4X8TL 4O02B 2XC4L 1OB1C 2P28B 3OLUA 5CISA 1APOA 1G1RA 2TGFA 1CVWL 1PXXA 1YGCL 1Z6EL 1ATEA 1V1HA 1KLOA 3KCGL 2WFTA 1NFUB 2I9AA 2RHPA 3HO5A 1ATAA 1EQGA 2VVVL 3P5BL 1A3PA 1FJSL 1PFXL 3HPTA 1W8BL 4GU4A
chains in the Genus database with same CATH topology
1QFKL 2BOUA 1V3XB 2VWNL 3Q7DA 1LQDA 3ELAL 3LN0A 2VJ3A 2MGRA 3BPSE 1KIGL 4Y71B 3U73A 4NA9L 4MMZB 1ZAQA 1PTHA 1EPJA 2Y5HL 1O5DL 4BXSA 4BXWA 2B7DL 1DVAL 1NFYB 2VWOL 1G2LB 4Z0KB 3TZIA 4YZUB 1EPGA 1M1XB 5FDQA 1EAIC 1YO8A 2XBYL 3Q3KB 1FFMA 5COXA 1W7XL 1YUKB 3F1SB 1TLEA 4ZXYL 3PGHA 2MGPA 4RUTA 1JV2B 1SZBA 2KNIA 1TPGA 1N1IA 3LTGD 2Y80B 4Y6DB 4CSYA 1IQLL 2EI6B 2BOKL 1ADXA 3ZYJB 2P3TA 2Y5GL 5L30L 3N8VA 5L2YL 4D0FA 3MDLA 4Z6AL 3N8XA 4X8UL 1X7AL 1DIYA 1EMNA 2DDUA 2Y82B 2W2QE 2W2OE 3IITB 1NFWB 1IOXA 1P9JA 4Y7AB 4JZFL 3NTGA 1F0RB 3BT1A 3F6UL 4MMXB 2FD6A 1KLIL 1IQJL 3SOQA 2I9BA 4JZDL 1DQBA 4A7IA 1U8CB 1NQLB 1IVOC 1EPIA 5JB9E 4FM5A 2EI7B 1IP0A 3TK6B 2FLRL 2P3FN 4LMFA 4RS0A 5IKQA 1UZJA 2J95B 3LC5B 5KIRA 4ZAEB 5JB8E 3QH0A 3ENSA 1APQA 2F9BL 1IGXA 2VVUL 3LC3B 1I0UA 4BTIA 1YUFA 2Y7XB 4A94C 1GK5A 1WHEA 4OTYA 3SW2A 2W3KB 2FZZL 1CCVA 1IQEL 3FCSB 2BQ7A 2Y5FL 1MQ5L 2WZPP 5CKMA 4PH9A 2Y81B 5JBCE 1LPGA 3V64C 1BF9A 2PUQL 1KSNB 1XDTR 4RRYA 1HCGB 1EPHA 1J9CL 2VWMK 2K2TA 1LPKA 2YGOA 3M36L 5CKQA 5IKVA 5KN5C 2KV4A 1NFXB 3NTBA 3MQEA 1MOXC 2WPIE 1TOZA 4ZHAB 1FSBA 2P3FL 3LIWB 2XBVL 2G00L 1JL9A 2WYGB 1C5MF 2J38B 4D90A 1RFNB 1HAFA 4OTJA 1U67A 1CQEA 2VH0B 2W2NE 2P95L 3V65B 4M11A 1WHFA 3N8YB 1EMOA 2PHBB 1LPZA 2VWLL 1IQFL 3GCXE 1HRFA 2KL7A 2XC5L 3CFWA 4XLWA 1ATDA 2UWLB 4Y79B 1IQGL 4BDWA 2P16L 4XL1A 1Q4GA 4C16A 2MHPA 3ZYIB 1HREA 1NZIA 1JBUL 2EI8B 2P26A 3N8WA 4O1ZA 3RR3A 3ASIA 2WFXB 1G1QA 2BOXA 3KQEL 6COXA 1FF7A 3U7UG 1G1TA 5JVYA 3TH3L 2GD4A 2WPKE 3GISX 2WPLE 5JBAE 1DX5I 5JVZA 1XFEA 3KK6A 1IOEL 4COXA 2UWPB 2BMGA 1CCFA 2W26B 1N7DA 3KQCL 2J2UB 1XKAL 4X8SL 3IJEB 4XBMA 1IQHL 1NT0A 3GCWE 3CS7L 1HZ8A 4BTTA 1EQHA 1XKBA 3HO3A 5JBBE 3ZYGA 1YUGA 1FAXL 4CUEA 2Y38A 1L3YA 5JW1A 4CUFA 1UZQA 2WPJE 3N8WB 4G1MB 2Q1JB 1IJQA 3LAQA 4D0EA 4E1GA 3N8YA 2OYEP 4RRXA 1EZQB 4ISHL 1PGEA 2P93L 2K2SB 3M37L 2JKHL 3SOVA 3KRKA 4ZH8B 2VH6B 3C9AC 3NJPC 2M74A 1HT5A 2P3UA 2VVCK 3KQBL 4RRZA 1UZKA 5L2ZL 1G2MB 2FLBL 3HS6A 2W3IB 4M10A 4X8VL 2BQ6A 3HO4A 4BTUA 3EGFA 3KQDL 2WG4B 2NPRA 1NPEB 3R05A 5EGMB 4RRWA 2AYLA 5IKTA 2CJIB 1K36A 1ATBA 5IKRA 1HX2A 3BT2A 1MQ6L 3DEMA 2J34B 1PRHA 4NGAL 2RA0L 2W2ME 2H9EL 2BO2A 3NT1A 2P94L 2BQWA 3H5CB 2YGPA 1COUA 2Y7ZB 3HS7A 4JYUL 2BOHA 1CEJA 3KL6B 1L5GB 4MMYB 4Y7BB 1B9WA 4TGFA 1AUTL 5K0HB 2ADXA 2BZ6L 1HJ7A 1Z6CA 4ZXXL 3CENL 4CUDA 3QMOA 2UWOB 1LMJA 2WG3C 1IQIL 3TGFA 2WYJB 2OYUP 1F0SB 4Z0LA 1HAEA 3OLTA 4YT6L 3LTFB 5CKNA 1FAKL 3FFGL 3HS5A 2YGQA 1P0SL 2XBXL 4Y76B 1EBVA 1G1SA 4JYVL 1F7MA 3S6XA 3N8ZA 2WPHE 1CVUA 5E8DA 2J4IB 2KB9A 1F7EA 1IQML 4NG9L 1CX2A 1URKA 3LN1A 4ISIL 4LORA 2PR3B 2FLGA 3K9XA 4BDXA 5F1AA 2XBWL 1KLJL 3POYA 4YT7L 2W86A 2D1JB 2H9EC 3QCWA 1FE2A 4JZEL 5F19A 3FBYA 1IQKL 3TBDA 2XC0L 1DDXA 4AQTA 3SOBB 1K37A 2W2PE 1WU1B 1EGFA 3TK5B 5I46L 1LMMA 1UZPA 1HT8A 2WPME 1IGZA 3CA7A 2J94B 1IQNL 2RNLA 4X8TL 4O02B 2XC4L 1OB1C 2P28B 3OLUA 5CISA 1APOA 1G1RA 2TGFA 1CVWL 1PXXA 1YGCL 1Z6EL 1ATEA 1KLOA 3KCGL 2WFTA 1NFUB 2I9AA 2RHPA 3HO5A 1ATAA 1EQGA 2VVVL 3P5BL 1A3PA 1FJSL 1PFXL 3HPTA 1W8BL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QFK L;  2BOU A;  1V3X B;  2VWN L;  3Q7D A;  1LQD A;  3ELA L;  3LN0 A;  2VJ3 A;  2MGR A;  3BPS E;  1KIG L;  4Y71 B;  3U73 A;  4NA9 L;  4MMZ B;  1ZAQ A;  1PTH A;  1EPJ A;  2Y5H L;  1O5D L;  4BXS A;  4BXW A;  2B7D L;  1DVA L;  1NFY B;  2VWO L;  1G2L B;  4Z0K B;  3TZI A;  4YZU B;  1EPG A;  1M1X B;  5FDQ A;  1EAI C;  1YO8 A;  2XBY L;  3Q3K B;  1FFM A;  5COX A;  1W7X L;  1YUK B;  3F1S B;  1TLE A;  4ZXY L;  3PGH A;  2MGP A;  4RUT A;  1JV2 B;  1SZB A;  1TPG A;  1N1I A;  3LTG D;  2Y80 B;  4Y6D B;  4CSY A;  1IQL L;  2EI6 B;  2BOK L;  1ADX A;  3ZYJ B;  2P3T A;  2Y5G L;  5L30 L;  3N8V A;  5L2Y L;  4D0F A;  3MDL A;  4Z6A L;  3N8X A;  4X8U L;  1X7A L;  1DIY A;  1EMN A;  2DDU A;  2Y82 B;  2W2Q E;  2W2O E;  3IIT B;  1NFW B;  1IOX A;  1P9J A;  4Y7A B;  4JZF L;  3NTG A;  1F0R B;  3BT1 A;  3F6U L;  4MMX B;  2FD6 A;  1KLI L;  1IQJ L;  3SOQ A;  2I9B A;  4JZD L;  1DQB A;  4A7I A;  1U8C B;  1NQL B;  1IVO C;  1EPI A;  5JB9 E;  4FM5 A;  2EI7 B;  1IP0 A;  3TK6 B;  2FLR L;  2P3F N;  4LMF A;  4RS0 A;  5IKQ A;  1UZJ A;  2J95 B;  3LC5 B;  5KIR A;  4ZAE B;  5JB8 E;  3QH0 A;  3ENS A;  1APQ A;  2F9B L;  1IGX A;  2VVU L;  3LC3 B;  1I0U A;  4BTI A;  1YUF A;  2Y7X B;  1GK5 A;  1WHE A;  4OTY A;  3SW2 A;  2W3K B;  2FZZ L;  1CCV A;  1IQE L;  3FCS B;  2BQ7 A;  2Y5F L;  1MQ5 L;  5CKM A;  4PH9 A;  2Y81 B;  5JBC E;  1LPG A;  3V64 C;  1BF9 A;  2PUQ L;  1KSN B;  1XDT R;  4RRY A;  1HCG B;  1EPH A;  1J9C L;  2VWM K;  2K2T A;  1LPK A;  2YGO A;  3M36 L;  5CKQ A;  5IKV A;  5KN5 C;  2KV4 A;  1NFX B;  3NTB A;  3MQE A;  1MOX C;  2WPI E;  1TOZ A;  4ZHA B;  1FSB A;  2P3F L;  3LIW B;  2XBV L;  2G00 L;  1JL9 A;  2WYG B;  1C5M F;  2J38 B;  4D90 A;  1RFN B;  1HAF A;  4OTJ A;  1U67 A;  1CQE A;  2VH0 B;  2W2N E;  2P95 L;  3V65 B;  4M11 A;  1WHF A;  3N8Y B;  1EMO A;  2PHB B;  1LPZ A;  2VWL L;  1IQF L;  3GCX E;  1HRF A;  2KL7 A;  2XC5 L;  3CFW A;  4XLW A;  1ATD A;  2UWL B;  4Y79 B;  1IQG L;  4BDW A;  2P16 L;  4XL1 A;  1Q4G A;  4C16 A;  2MHP A;  3ZYI B;  1HRE A;  1NZI A;  1JBU L;  2EI8 B;  2P26 A;  3N8W A;  4O1Z A;  3RR3 A;  3ASI A;  2WFX B;  1G1Q A;  2BOX A;  3KQE L;  6COX A;  1FF7 A;  3U7U G;  1G1T A;  5JVY A;  3TH3 L;  2GD4 A;  2WPK E;  3GIS X;  2WPL E;  5JBA E;  1DX5 I;  5JVZ A;  1XFE A;  3KK6 A;  1IOE L;  4COX A;  2UWP B;  2BMG A;  1CCF A;  2W26 B;  1N7D A;  3KQC L;  2J2U B;  1XKA L;  4X8S L;  3IJE B;  4XBM A;  1IQH L;  1NT0 A;  3GCW E;  3CS7 L;  1HZ8 A;  4BTT A;  1EQH A;  1XKB A;  3HO3 A;  5JBB E;  3ZYG A;  1YUG A;  1FAX L;  4CUE A;  2Y38 A;  1L3Y A;  5JW1 A;  4CUF A;  1UZQ A;  2WPJ E;  3N8W B;  4G1M B;  2Q1J B;  1IJQ A;  3LAQ A;  4D0E A;  4E1G A;  3N8Y A;  2OYE P;  4RRX A;  1EZQ B;  4ISH L;  1PGE A;  2P93 L;  2K2S B;  3M37 L;  2JKH L;  3SOV A;  3KRK A;  4ZH8 B;  2VH6 B;  3C9A C;  3NJP C;  2M74 A;  1HT5 A;  2P3U A;  2VVC K;  3KQB L;  4RRZ A;  1UZK A;  5L2Z L;  1G2M B;  2FLB L;  3HS6 A;  2W3I B;  4M10 A;  4X8V L;  2BQ6 A;  3HO4 A;  4BTU A;  3EGF A;  3KQD L;  2WG4 B;  2NPR A;  1NPE B;  3R05 A;  5EGM B;  4RRW A;  2AYL A;  5IKT A;  2CJI B;  1K36 A;  1ATB A;  5IKR A;  1HX2 A;  3BT2 A;  1MQ6 L;  3DEM A;  2J34 B;  1PRH A;  4NGA L;  2RA0 L;  2W2M E;  2H9E L;  2BO2 A;  3NT1 A;  2P94 L;  2BQW A;  3H5C B;  2YGP A;  1COU A;  2Y7Z B;  3HS7 A;  4JYU L;  2BOH A;  1CEJ A;  3KL6 B;  1L5G B;  4MMY B;  4Y7B B;  1B9W A;  4TGF A;  1AUT L;  5K0H B;  2ADX A;  2BZ6 L;  1HJ7 A;  1Z6C A;  4ZXX L;  3CEN L;  4CUD A;  3QMO A;  2UWO B;  1LMJ A;  2WG3 C;  1IQI L;  3TGF A;  2WYJ B;  2OYU P;  1F0S B;  4Z0L A;  1HAE A;  3OLT A;  4YT6 L;  3LTF B;  5CKN A;  1FAK L;  3FFG L;  3HS5 A;  1P0S L;  2XBX L;  4Y76 B;  1EBV A;  1G1S A;  4JYV L;  1F7M A;  3N8Z A;  2WPH E;  1CVU A;  5E8D A;  2J4I B;  2KB9 A;  1F7E A;  1IQM L;  4NG9 L;  1CX2 A;  1URK A;  3LN1 A;  4ISI L;  4LOR A;  2PR3 B;  2FLG A;  3K9X A;  4BDX A;  5F1A A;  2XBW L;  1KLJ L;  3POY A;  4YT7 L;  2W86 A;  2D1J B;  3QCW A;  1FE2 A;  4JZE L;  5F19 A;  3FBY A;  1IQK L;  3TBD A;  2XC0 L;  1DDX A;  4AQT A;  3SOB B;  1K37 A;  2W2P E;  1WU1 B;  1EGF A;  3TK5 B;  5I46 L;  1UZP A;  1HT8 A;  2WPM E;  1IGZ A;  3CA7 A;  2J94 B;  1IQN L;  2RNL A;  4X8T L;  4O02 B;  2XC4 L;  1OB1 C;  2P28 B;  3OLU A;  5CIS A;  1APO A;  1G1R A;  2TGF A;  1CVW L;  1PXX A;  1YGC L;  1Z6E L;  1ATE A;  1KLO A;  3KCG L;  2WFT A;  1NFU B;  2I9A A;  2RHP A;  3HO5 A;  1ATA A;  1EQG A;  2VVV L;  3P5B L;  1A3P A;  1FJS L;  1PFX L;  3HPT A;  1W8B L; 
#chains in the Genus database with same CATH topology
 1QFK L;  2BOU A;  1V3X B;  2VWN L;  3Q7D A;  1LQD A;  3ELA L;  3LN0 A;  2VJ3 A;  2MGR A;  3BPS E;  1KIG L;  4Y71 B;  3U73 A;  4NA9 L;  4MMZ B;  1ZAQ A;  1PTH A;  1EPJ A;  2Y5H L;  1KKE A;  1O5D L;  4BXS A;  4BXW A;  2B7D L;  1DVA L;  1NFY B;  2VWO L;  1G2L B;  4Z0K B;  3TZI A;  4YZU B;  1EPG A;  1M1X B;  5FDQ A;  1EAI C;  1YO8 A;  2XBY L;  3Q3K B;  1FFM A;  5COX A;  1W7X L;  1YUK B;  3F1S B;  1TLE A;  4ZXY L;  3PGH A;  2MGP A;  4RUT A;  1JV2 B;  1SZB A;  2KNI A;  1TPG A;  1N1I A;  3LTG D;  2Y80 B;  4Y6D B;  4CSY A;  1IQL L;  2EI6 B;  2BOK L;  1ADX A;  3ZYJ B;  2P3T A;  2Y5G L;  5L30 L;  3N8V A;  5L2Y L;  4D0F A;  3MDL A;  4Z6A L;  3N8X A;  4X8U L;  1X7A L;  1DIY A;  1EMN A;  2DDU A;  2Y82 B;  2W2Q E;  2W2O E;  3IIT B;  1NFW B;  1IOX A;  1P9J A;  4Y7A B;  4JZF L;  3NTG A;  1F0R B;  3BT1 A;  3F6U L;  4MMX B;  2FD6 A;  1KLI L;  1IQJ L;  3SOQ A;  2I9B A;  4JZD L;  1DQB A;  4A7I A;  1U8C B;  1NQL B;  1IVO C;  1EPI A;  5JB9 E;  4FM5 A;  2EI7 B;  2HOX A;  1IP0 A;  3TK6 B;  2FLR L;  2P3F N;  4LMF A;  4RS0 A;  5IKQ A;  1UZJ A;  2J95 B;  3LC5 B;  5KIR A;  4ZAE B;  5JB8 E;  3QH0 A;  3ENS A;  1V1I A;  1APQ A;  2F9B L;  1IGX A;  2VVU L;  3LC3 B;  1I0U A;  4BTI A;  1YUF A;  2Y7X B;  4A94 C;  1GK5 A;  1WHE A;  4OTY A;  3SW2 A;  2W3K B;  2FZZ L;  1CCV A;  1IQE L;  3FCS B;  2BQ7 A;  2Y5F L;  1MQ5 L;  2WZP P;  5CKM A;  4PH9 A;  2Y81 B;  5JBC E;  1LPG A;  3V64 C;  1BF9 A;  2PUQ L;  1KSN B;  1XDT R;  4RRY A;  1HCG B;  1EPH A;  1J9C L;  2VWM K;  2K2T A;  1LPK A;  2YGO A;  3M36 L;  5CKQ A;  5IKV A;  5KN5 C;  2KV4 A;  1NFX B;  3NTB A;  3MQE A;  1MOX C;  2WPI E;  1TOZ A;  4ZHA B;  1FSB A;  2P3F L;  3LIW B;  2XBV L;  2G00 L;  1JL9 A;  2WYG B;  1C5M F;  2J38 B;  4D90 A;  1RFN B;  1HAF A;  4OTJ A;  1U67 A;  1CQE A;  2VH0 B;  2W2N E;  2P95 L;  3V65 B;  4M11 A;  1WHF A;  3N8Y B;  1EMO A;  2PHB B;  1LPZ A;  2VWL L;  1IQF L;  3GCX E;  1HRF A;  2KL7 A;  2XC5 L;  3CFW A;  4XLW A;  1ATD A;  2UWL B;  4Y79 B;  1IQG L;  4BDW A;  2P16 L;  4XL1 A;  1Q4G A;  4C16 A;  2MHP A;  3ZYI B;  1HRE A;  1NZI A;  1JBU L;  2EI8 B;  2P26 A;  3N8W A;  4O1Z A;  3RR3 A;  3ASI A;  2WFX B;  1G1Q A;  2BOX A;  3KQE L;  6COX A;  1FF7 A;  3U7U G;  1G1T A;  5JVY A;  3TH3 L;  2GD4 A;  2WPK E;  3GIS X;  2WPL E;  5JBA E;  1DX5 I;  5JVZ A;  1XFE A;  3KK6 A;  1IOE L;  4COX A;  2UWP B;  2BMG A;  1CCF A;  2W26 B;  1N7D A;  3KQC L;  2J2U B;  1XKA L;  4X8S L;  3IJE B;  4XBM A;  1IQH L;  1NT0 A;  3GCW E;  3CS7 L;  1HZ8 A;  4BTT A;  1EQH A;  1XKB A;  3HO3 A;  5JBB E;  3ZYG A;  1YUG A;  2HOR A;  1FAX L;  4CUE A;  2Y38 A;  1L3Y A;  5JW1 A;  2JJL A;  4CUF A;  1UZQ A;  2WPJ E;  3N8W B;  4G1M B;  2Q1J B;  1IJQ A;  3LAQ A;  4D0E A;  4E1G A;  3N8Y A;  2OYE P;  4RRX A;  1EZQ B;  4ISH L;  1PGE A;  2P93 L;  2K2S B;  3M37 L;  2JKH L;  3SOV A;  3KRK A;  4ZH8 B;  2VH6 B;  3C9A C;  3NJP C;  2M74 A;  1HT5 A;  2P3U A;  2VVC K;  3KQB L;  4RRZ A;  1UZK A;  5L2Z L;  1G2M B;  2FLB L;  3HS6 A;  2BT7 A;  2W3I B;  4M10 A;  4X8V L;  2BQ6 A;  3HO4 A;  4BTU A;  3EGF A;  1QIU A;  3KQD L;  2WG4 B;  2NPR A;  1NPE B;  3R05 A;  5EGM B;  4RRW A;  2AYL A;  5IKT A;  2CJI B;  1K36 A;  1ATB A;  5IKR A;  1HX2 A;  3BT2 A;  1MQ6 L;  3DEM A;  2J34 B;  1PRH A;  4NGA L;  2BT8 A;  2RA0 L;  2W2M E;  2H9E L;  2BO2 A;  3NT1 A;  2P94 L;  2BQW A;  3H5C B;  2YGP A;  1COU A;  2Y7Z B;  3HS7 A;  4JYU L;  2BOH A;  1CEJ A;  3KL6 B;  1L5G B;  4MMY B;  4Y7B B;  1B9W A;  4TGF A;  2VRS A;  1AUT L;  5K0H B;  2ADX A;  2BZ6 L;  1HJ7 A;  1Z6C A;  4ZXX L;  1LK9 A;  3CEN L;  4CUD A;  3QMO A;  2UWO B;  4GU3 A;  1LMJ A;  2WG3 C;  1IQI L;  3TGF A;  2WYJ B;  2OYU P;  1F0S B;  4Z0L A;  1HAE A;  3OLT A;  4YT6 L;  3LTF B;  5CKN A;  2BSF A;  1FAK L;  3FFG L;  3HS5 A;  2YGQ A;  1P0S L;  2XBX L;  4Y76 B;  1EBV A;  1G1S A;  4JYV L;  1F7M A;  3S6X A;  3N8Z A;  2WPH E;  1CVU A;  5E8D A;  2J4I B;  2KB9 A;  1F7E A;  1IQM L;  4NG9 L;  1CX2 A;  1URK A;  3LN1 A;  4ISI L;  4LOR A;  2PR3 B;  2FLG A;  3K9X A;  4BDX A;  5F1A A;  2XBW L;  1KLJ L;  3POY A;  4YT7 L;  2W86 A;  2D1J B;  2H9E C;  3QCW A;  1FE2 A;  4JZE L;  5F19 A;  3FBY A;  1IQK L;  3TBD A;  2XC0 L;  1DDX A;  4AQT A;  3SOB B;  1K37 A;  2W2P E;  1WU1 B;  1EGF A;  3TK5 B;  5I46 L;  1LMM A;  1UZP A;  1HT8 A;  2WPM E;  1IGZ A;  3CA7 A;  2J94 B;  1IQN L;  2RNL A;  4X8T L;  4O02 B;  2XC4 L;  1OB1 C;  2P28 B;  3OLU A;  5CIS A;  1APO A;  1G1R A;  2TGF A;  1CVW L;  1PXX A;  1YGC L;  1Z6E L;  1ATE A;  1V1H A;  1KLO A;  3KCG L;  2WFT A;  1NFU B;  2I9A A;  2RHP A;  3HO5 A;  1ATA A;  1EQG A;  2VVV L;  3P5B L;  1A3P A;  1FJS L;  1PFX L;  3HPT A;  1W8B L;  4GU4 A; 
#chains in the Genus database with same CATH homology
 1QFK L;  2BOU A;  1V3X B;  2VWN L;  3Q7D A;  1LQD A;  3ELA L;  3LN0 A;  2VJ3 A;  2MGR A;  3BPS E;  1KIG L;  4Y71 B;  3U73 A;  4NA9 L;  4MMZ B;  1ZAQ A;  1PTH A;  1EPJ A;  2Y5H L;  1O5D L;  4BXS A;  4BXW A;  2B7D L;  1DVA L;  1NFY B;  2VWO L;  1G2L B;  4Z0K B;  3TZI A;  4YZU B;  1EPG A;  1M1X B;  5FDQ A;  1EAI C;  1YO8 A;  2XBY L;  3Q3K B;  1FFM A;  5COX A;  1W7X L;  1YUK B;  3F1S B;  1TLE A;  4ZXY L;  3PGH A;  2MGP A;  4RUT A;  1JV2 B;  1SZB A;  2KNI A;  1TPG A;  1N1I A;  3LTG D;  2Y80 B;  4Y6D B;  4CSY A;  1IQL L;  2EI6 B;  2BOK L;  1ADX A;  3ZYJ B;  2P3T A;  2Y5G L;  5L30 L;  3N8V A;  5L2Y L;  4D0F A;  3MDL A;  4Z6A L;  3N8X A;  4X8U L;  1X7A L;  1DIY A;  1EMN A;  2DDU A;  2Y82 B;  2W2Q E;  2W2O E;  3IIT B;  1NFW B;  1IOX A;  1P9J A;  4Y7A B;  4JZF L;  3NTG A;  1F0R B;  3BT1 A;  3F6U L;  4MMX B;  2FD6 A;  1KLI L;  1IQJ L;  3SOQ A;  2I9B A;  4JZD L;  1DQB A;  4A7I A;  1U8C B;  1NQL B;  1IVO C;  1EPI A;  5JB9 E;  4FM5 A;  2EI7 B;  1IP0 A;  3TK6 B;  2FLR L;  2P3F N;  4LMF A;  4RS0 A;  5IKQ A;  1UZJ A;  2J95 B;  3LC5 B;  5KIR A;  4ZAE B;  5JB8 E;  3QH0 A;  3ENS A;  1APQ A;  2F9B L;  1IGX A;  2VVU L;  3LC3 B;  1I0U A;  4BTI A;  1YUF A;  2Y7X B;  4A94 C;  1GK5 A;  1WHE A;  4OTY A;  3SW2 A;  2W3K B;  2FZZ L;  1CCV A;  1IQE L;  3FCS B;  2BQ7 A;  2Y5F L;  1MQ5 L;  2WZP P;  5CKM A;  4PH9 A;  2Y81 B;  5JBC E;  1LPG A;  3V64 C;  1BF9 A;  2PUQ L;  1KSN B;  1XDT R;  4RRY A;  1HCG B;  1EPH A;  1J9C L;  2VWM K;  2K2T A;  1LPK A;  2YGO A;  3M36 L;  5CKQ A;  5IKV A;  5KN5 C;  2KV4 A;  1NFX B;  3NTB A;  3MQE A;  1MOX C;  2WPI E;  1TOZ A;  4ZHA B;  1FSB A;  2P3F L;  3LIW B;  2XBV L;  2G00 L;  1JL9 A;  2WYG B;  1C5M F;  2J38 B;  4D90 A;  1RFN B;  1HAF A;  4OTJ A;  1U67 A;  1CQE A;  2VH0 B;  2W2N E;  2P95 L;  3V65 B;  4M11 A;  1WHF A;  3N8Y B;  1EMO A;  2PHB B;  1LPZ A;  2VWL L;  1IQF L;  3GCX E;  1HRF A;  2KL7 A;  2XC5 L;  3CFW A;  4XLW A;  1ATD A;  2UWL B;  4Y79 B;  1IQG L;  4BDW A;  2P16 L;  4XL1 A;  1Q4G A;  4C16 A;  2MHP A;  3ZYI B;  1HRE A;  1NZI A;  1JBU L;  2EI8 B;  2P26 A;  3N8W A;  4O1Z A;  3RR3 A;  3ASI A;  2WFX B;  1G1Q A;  2BOX A;  3KQE L;  6COX A;  1FF7 A;  3U7U G;  1G1T A;  5JVY A;  3TH3 L;  2GD4 A;  2WPK E;  3GIS X;  2WPL E;  5JBA E;  1DX5 I;  5JVZ A;  1XFE A;  3KK6 A;  1IOE L;  4COX A;  2UWP B;  2BMG A;  1CCF A;  2W26 B;  1N7D A;  3KQC L;  2J2U B;  1XKA L;  4X8S L;  3IJE B;  4XBM A;  1IQH L;  1NT0 A;  3GCW E;  3CS7 L;  1HZ8 A;  4BTT A;  1EQH A;  1XKB A;  3HO3 A;  5JBB E;  3ZYG A;  1YUG A;  1FAX L;  4CUE A;  2Y38 A;  1L3Y A;  5JW1 A;  4CUF A;  1UZQ A;  2WPJ E;  3N8W B;  4G1M B;  2Q1J B;  1IJQ A;  3LAQ A;  4D0E A;  4E1G A;  3N8Y A;  2OYE P;  4RRX A;  1EZQ B;  4ISH L;  1PGE A;  2P93 L;  2K2S B;  3M37 L;  2JKH L;  3SOV A;  3KRK A;  4ZH8 B;  2VH6 B;  3C9A C;  3NJP C;  2M74 A;  1HT5 A;  2P3U A;  2VVC K;  3KQB L;  4RRZ A;  1UZK A;  5L2Z L;  1G2M B;  2FLB L;  3HS6 A;  2W3I B;  4M10 A;  4X8V L;  2BQ6 A;  3HO4 A;  4BTU A;  3EGF A;  3KQD L;  2WG4 B;  2NPR A;  1NPE B;  3R05 A;  5EGM B;  4RRW A;  2AYL A;  5IKT A;  2CJI B;  1K36 A;  1ATB A;  5IKR A;  1HX2 A;  3BT2 A;  1MQ6 L;  3DEM A;  2J34 B;  1PRH A;  4NGA L;  2RA0 L;  2W2M E;  2H9E L;  2BO2 A;  3NT1 A;  2P94 L;  2BQW A;  3H5C B;  2YGP A;  1COU A;  2Y7Z B;  3HS7 A;  4JYU L;  2BOH A;  1CEJ A;  3KL6 B;  1L5G B;  4MMY B;  4Y7B B;  1B9W A;  4TGF A;  1AUT L;  5K0H B;  2ADX A;  2BZ6 L;  1HJ7 A;  1Z6C A;  4ZXX L;  3CEN L;  4CUD A;  3QMO A;  2UWO B;  1LMJ A;  2WG3 C;  1IQI L;  3TGF A;  2WYJ B;  2OYU P;  1F0S B;  4Z0L A;  1HAE A;  3OLT A;  4YT6 L;  3LTF B;  5CKN A;  1FAK L;  3FFG L;  3HS5 A;  2YGQ A;  1P0S L;  2XBX L;  4Y76 B;  1EBV A;  1G1S A;  4JYV L;  1F7M A;  3S6X A;  3N8Z A;  2WPH E;  1CVU A;  5E8D A;  2J4I B;  2KB9 A;  1F7E A;  1IQM L;  4NG9 L;  1CX2 A;  1URK A;  3LN1 A;  4ISI L;  4LOR A;  2PR3 B;  2FLG A;  3K9X A;  4BDX A;  5F1A A;  2XBW L;  1KLJ L;  3POY A;  4YT7 L;  2W86 A;  2D1J B;  2H9E C;  3QCW A;  1FE2 A;  4JZE L;  5F19 A;  3FBY A;  1IQK L;  3TBD A;  2XC0 L;  1DDX A;  4AQT A;  3SOB B;  1K37 A;  2W2P E;  1WU1 B;  1EGF A;  3TK5 B;  5I46 L;  1LMM A;  1UZP A;  1HT8 A;  2WPM E;  1IGZ A;  3CA7 A;  2J94 B;  1IQN L;  2RNL A;  4X8T L;  4O02 B;  2XC4 L;  1OB1 C;  2P28 B;  3OLU A;  5CIS A;  1APO A;  1G1R A;  2TGF A;  1CVW L;  1PXX A;  1YGC L;  1Z6E L;  1ATE A;  1KLO A;  3KCG L;  2WFT A;  1NFU B;  2I9A A;  2RHP A;  3HO5 A;  1ATA A;  1EQG A;  2VVV L;  3P5B L;  1A3P A;  1FJS L;  1PFX L;  3HPT A;  1W8B L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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