1PQFA

Glycine 24 to serine mutation of aspartate decarboxylase
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
127
structure length
126
Chain Sequence
PRGSMIRTMLQGKLHRVKVTHADLHYESSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords Aspartate 1-decarboxylase
total genus 35
structure length 126
sequence length 127
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqfA00
1R27A 1TWHA 3GTKA 2JA6A 3QC8A 4AAYA 3IR7A 2NYAA 4AZDA 3PLXB 1KQFA 1TWAA 3OUGA 3HU1A 1H0HA 5C1BA 2NVXA 1Y5IA 1E32A 3GTOA 1PYUB 3IR6A 3QQ8A 1QDNA 2NAPA 2VPWA 1CZ4A 1DMRA 4AONB 2JIPA 1TWGA 2PJHB 2V3VA 3HU3A 2VPYA 1WCMA 2IV2X 4DMRA 2DMRA 1SFOA 2JA7A 2VPXA 2KI8A 4CS0A 1Q16A 3HU2A 4AOKB 4C2MA 1Y1WA 1E5VA 2E2IA 2VUMA 3GTGA 2YU9A 2R7ZA 3FKIA 2JIRA 1UHDA 3GTPA 4CRYG 4AYBA 1PQFA 1AA6A 2R92A 1TMOA 1TWFA 3TIWA 3H0GA 1EU1A 1FDOA 3CF2A 3O5AA 5FTNA 1R9TA 1E60A 3QQ7A 1I50A 5DYGA 1UHEA 1PYQA 1PPYA 1SIWA 4KO8A 5EPPA 1I3QA 2EEOB 1G8JA 4GA5A 1AW8B 1QCSA 1PT0A 2E7ZA 4KLNA 5FTLA 5FTMA 3GTLA 5DYIA 2JIQA 2R93A 1WLFA 2C45A 2JIMA 1CR5A 2E2HA 2VPZA 4CRZA 2JA5A 5C18A 1R7RA 1VC3B 1KQGA 5B6CA 1YLEA 2PMZA 1PT1A 1DMSA 1OGYA 3CQZA 1G8KA 5GLFA 1PQEA 1S3SA 3DMRA 4GA6A 1PQHA 3HKZA 4KDLA 1CZ5A 1E61A 3GTJA 1K83A 5T5ID 5FTJA 1TWCA 1FDIA 1E18A 3GTQA 3IR5A 2Y0SA 4RV0A 5T5MD 2B63A 3GTMA 3TM7B 2V45A 4D7ZB 2WB1A 4KODA 2JIOA 4QIWA 3QWZA 2NVYA 1IW7D 1Y1VA 1Y4ZA 2WAQA 5FTKA 3ML1A 4KDIA 1H5NA
chains in the Genus database with same CATH superfamily
4FG2A 1R27A 1TWHA 3GTKA 2JA6A 3QC8A 4AAYA 3IR7A 5H4UA 1N10A 2NYAA 4AZDA 3CZBA 1L8FA 1ZC1A 3PLXB 4AVRA 1KQFA 1YNJD 1TWAA 4FERA 3OUGA 3HU1A 1H0HA 4JP7A 5C1BA 2NVXA 2A6ED 4NOHA 1Y5IA 1E32A 2CW0D 3GTOA 1PYUB 3D30A 4JS7A 3X2HA 2BH0A 3IR6A 4L48A 3QQ8A 1QDNA 2NAPA 4JJOA 4ZM7A 2VPWA 1CZ4A 1DMRA 4AONB 2JIPA 4FG4A 5GLYA 1SMYD 1TWGA 2PJHB 2KQAA 2V3VA 2A6HD 3X2KA 2YUJA 3HU3A 2VPYA 5GM9A 1WCMA 2IV2X 4DMRA 2DMRA 2A69D 1SFOA 2JA7A 2VPXA 2PJJA 2KI8A 4CS0A 1Q16A 3HU2A 4AOKB 4C2MA 1Y1WA 1E5VA 2E2IA 2VUMA 3GTGA 2YU9A 4ENGA 2R7ZA 3FKIA 2JIRA 1UHDA 3X2LA 1OA7A 3GTPA 4CRYG 4AYBA 1PQFA 3M3GA 1AA6A 2R92A 1TMOA 2HCZX 1HD5A 1TWFA 3TIWA 3H0GA 3X2OA 2G5DA 2PI8A 1EU1A 1OA9A 1FDOA 3CF2A 3O5AA 3X2IA 4FFTA 5FTNA 1R9TA 1E60A 5GLXA 3QQ7A 1I50A 5DYGA 1UHEA 1PYQA 1PPYA 4JP6A 1SIWA 4KO8A 2AE0X 5EPPA 1I3QA 3SULA 2EEOB 1G8JA 4GA5A 1AW8B 1QCSA 1PT0A 1YNND 2E7ZA 4KLNA 5FTLA 5FTMA 1BW3A 2PNWA 2ENGA 3GTLA 5DYIA 2JIQA 3SUKA 2BE5D 2R93A 1WLFA 2C45A 2JIMA 1CR5A 2E2HA 2VPZA 4CRZA 2JA5A 5C18A 1R7RA 3SUMA 1VC3B 1KQGA 5B6CA 1YLEA 2PMZA 4JCWA 1PT1A 1DMSA 1OGYA 3ENGA 3CQZA 1G8KA 5GLFA 1PQEA 1S3SA 3DMRA 4GA6A 1PQHA 3HKZA 4KDLA 1CZ5A 1E61A 3GTJA 1K83A 5T5ID 5FTJA 3X2NA 1TWCA 1FDIA 3X2MA 1E18A 3GTQA 3IR5A 2Y0SA 1ZYRD 2G6GA 4RV0A 5T5MD 2B63A 3GTMA 3TM7B 2V45A 3X2GA 1WC2A 3SUJA 2O5JD 4D7ZB 2WB1A 2PICA 4KODA 2JIOA 3X2JA 2GAEA 4QIWA 2A68D 3QWZA 2NVYA 1IW7D 1Y1VA 1Y4ZA 2WAQA 5FTKA 3ML1A 4KDIA 3X2PA 1BW4A 1H5NA
chains in the Genus database with same CATH topology
1R27A 1TWHA 3GTKA 2JA6A 3QC8A 4AAYA 3IR7A 2NYAA 4AZDA 3CZBA 1ZC1A 3PLXB 1KQFA 1YNJD 1TWAA 3OUGA 3HU1A 1H0HA 5C1BA 2NVXA 2A6ED 4NOHA 1Y5IA 1E32A 2CW0D 3GTOA 1PYUB 3IR6A 3QQ8A 1QDNA 2NAPA 2VPWA 1CZ4A 1DMRA 4AONB 2JIPA 1SMYD 1TWGA 2PJHB 2V3VA 2A6HD 2YUJA 3HU3A 2VPYA 1WCMA 2IV2X 4DMRA 2DMRA 2A69D 1SFOA 2JA7A 2VPXA 2PJJA 2KI8A 4CS0A 1Q16A 3HU2A 4AOKB 4C2MA 1Y1WA 1E5VA 2E2IA 2VUMA 3GTGA 2YU9A 2R7ZA 3FKIA 2JIRA 1UHDA 3GTPA 4CRYG 4AYBA 1PQFA 1AA6A 2R92A 1TMOA 1TWFA 3TIWA 3H0GA 2G5DA 2PI8A 1EU1A 1FDOA 3CF2A 3O5AA 5FTNA 1R9TA 1E60A 3QQ7A 1I50A 5DYGA 1UHEA 1PYQA 1PPYA 1SIWA 4KO8A 2AE0X 5EPPA 1I3QA 2EEOB 1G8JA 4GA5A 1AW8B 1QCSA 1PT0A 1YNND 2E7ZA 4KLNA 5FTLA 5FTMA 2PNWA 3GTLA 5DYIA 2JIQA 2BE5D 2R93A 1WLFA 2C45A 2JIMA 1CR5A 2E2HA 2VPZA 4CRZA 2JA5A 5C18A 1R7RA 1VC3B 1KQGA 5B6CA 1YLEA 2PMZA 1PT1A 1DMSA 1OGYA 3CQZA 1G8KA 5GLFA 1PQEA 1S3SA 3DMRA 4GA6A 1PQHA 3HKZA 4KDLA 1CZ5A 1E61A 3GTJA 1K83A 5T5ID 5FTJA 1TWCA 1FDIA 1E18A 3GTQA 3IR5A 2Y0SA 1ZYRD 2G6GA 4RV0A 5T5MD 2B63A 3GTMA 3TM7B 2V45A 2O5JD 4D7ZB 2WB1A 2PICA 4KODA 2JIOA 2GAEA 4QIWA 2A68D 3QWZA 2NVYA 1IW7D 1Y1VA 1Y4ZA 2WAQA 5FTKA 3ML1A 4KDIA 1H5NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R27 A;  1TWH A;  3GTK A;  2JA6 A;  3QC8 A;  4AAY A;  3IR7 A;  2NYA A;  4AZD A;  3PLX B;  1KQF A;  1TWA A;  3OUG A;  3HU1 A;  1H0H A;  5C1B A;  2NVX A;  1Y5I A;  1E32 A;  3GTO A;  1PYU B;  3IR6 A;  3QQ8 A;  1QDN A;  2NAP A;  2VPW A;  1CZ4 A;  1DMR A;  4AON B;  2JIP A;  1TWG A;  2PJH B;  2V3V A;  3HU3 A;  2VPY A;  1WCM A;  2IV2 X;  4DMR A;  2DMR A;  1SFO A;  2JA7 A;  2VPX A;  2KI8 A;  4CS0 A;  1Q16 A;  3HU2 A;  4AOK B;  4C2M A;  1Y1W A;  1E5V A;  2E2I A;  2VUM A;  3GTG A;  2YU9 A;  2R7Z A;  3FKI A;  2JIR A;  1UHD A;  3GTP A;  4CRY G;  4AYB A;  1PQF A;  1AA6 A;  2R92 A;  1TMO A;  1TWF A;  3TIW A;  3H0G A;  1EU1 A;  1FDO A;  3CF2 A;  3O5A A;  5FTN A;  1R9T A;  1E60 A;  3QQ7 A;  1I50 A;  5DYG A;  1UHE A;  1PYQ A;  1PPY A;  1SIW A;  4KO8 A;  5EPP A;  1I3Q A;  2EEO B;  1G8J A;  4GA5 A;  1AW8 B;  1QCS A;  1PT0 A;  2E7Z A;  4KLN A;  5FTL A;  5FTM A;  3GTL A;  5DYI A;  2JIQ A;  2R93 A;  1WLF A;  2C45 A;  2JIM A;  1CR5 A;  2E2H A;  2VPZ A;  4CRZ A;  2JA5 A;  5C18 A;  1R7R A;  1VC3 B;  1KQG A;  5B6C A;  1YLE A;  2PMZ A;  1PT1 A;  1DMS A;  1OGY A;  3CQZ A;  1G8K A;  5GLF A;  1PQE A;  1S3S A;  3DMR A;  4GA6 A;  1PQH A;  3HKZ A;  4KDL A;  1CZ5 A;  1E61 A;  3GTJ A;  1K83 A;  5T5I D;  5FTJ A;  1TWC A;  1FDI A;  1E18 A;  3GTQ A;  3IR5 A;  2Y0S A;  4RV0 A;  5T5M D;  2B63 A;  3GTM A;  3TM7 B;  2V45 A;  4D7Z B;  2WB1 A;  4KOD A;  2JIO A;  4QIW A;  3QWZ A;  2NVY A;  1IW7 D;  1Y1V A;  1Y4Z A;  2WAQ A;  5FTK A;  3ML1 A;  4KDI A;  1H5N A; 
#chains in the Genus database with same CATH topology
 4FG2 A;  1R27 A;  1TWH A;  3GTK A;  2JA6 A;  3QC8 A;  4AAY A;  3IR7 A;  5H4U A;  1N10 A;  2NYA A;  4AZD A;  3CZB A;  1L8F A;  1ZC1 A;  3PLX B;  4AVR A;  1KQF A;  1YNJ D;  1TWA A;  4FER A;  3OUG A;  3HU1 A;  1H0H A;  4JP7 A;  5C1B A;  2NVX A;  2A6E D;  4NOH A;  1Y5I A;  1E32 A;  2CW0 D;  3GTO A;  1PYU B;  3D30 A;  4JS7 A;  3X2H A;  2BH0 A;  3IR6 A;  4L48 A;  3QQ8 A;  1QDN A;  2NAP A;  4JJO A;  4ZM7 A;  2VPW A;  1CZ4 A;  1DMR A;  4AON B;  2JIP A;  4FG4 A;  5GLY A;  1SMY D;  1TWG A;  2PJH B;  2KQA A;  2V3V A;  2A6H D;  3X2K A;  2YUJ A;  3HU3 A;  2VPY A;  5GM9 A;  1WCM A;  2IV2 X;  4DMR A;  2DMR A;  2A69 D;  1SFO A;  2JA7 A;  2VPX A;  2PJJ A;  2KI8 A;  4CS0 A;  1Q16 A;  3HU2 A;  4AOK B;  4C2M A;  1Y1W A;  1E5V A;  2E2I A;  2VUM A;  3GTG A;  2YU9 A;  4ENG A;  2R7Z A;  3FKI A;  2JIR A;  1UHD A;  3X2L A;  1OA7 A;  3GTP A;  4CRY G;  4AYB A;  1PQF A;  3M3G A;  1AA6 A;  2R92 A;  1TMO A;  2HCZ X;  1HD5 A;  1TWF A;  3TIW A;  3H0G A;  3X2O A;  2G5D A;  2PI8 A;  1EU1 A;  1OA9 A;  1FDO A;  3CF2 A;  3O5A A;  3X2I A;  4FFT A;  5FTN A;  1R9T A;  1E60 A;  5GLX A;  3QQ7 A;  1I50 A;  5DYG A;  1UHE A;  1PYQ A;  1PPY A;  4JP6 A;  1SIW A;  4KO8 A;  2AE0 X;  5EPP A;  1I3Q A;  3SUL A;  2EEO B;  1G8J A;  4GA5 A;  1AW8 B;  1QCS A;  1PT0 A;  1YNN D;  2E7Z A;  4KLN A;  5FTL A;  5FTM A;  1BW3 A;  2PNW A;  2ENG A;  3GTL A;  5DYI A;  2JIQ A;  3SUK A;  2BE5 D;  2R93 A;  1WLF A;  2C45 A;  2JIM A;  1CR5 A;  2E2H A;  2VPZ A;  4CRZ A;  2JA5 A;  5C18 A;  1R7R A;  3SUM A;  1VC3 B;  1KQG A;  5B6C A;  1YLE A;  2PMZ A;  4JCW A;  1PT1 A;  1DMS A;  1OGY A;  3ENG A;  3CQZ A;  1G8K A;  5GLF A;  1PQE A;  1S3S A;  3DMR A;  4GA6 A;  1PQH A;  3HKZ A;  4KDL A;  1CZ5 A;  1E61 A;  3GTJ A;  1K83 A;  5T5I D;  5FTJ A;  3X2N A;  1TWC A;  1FDI A;  3X2M A;  1E18 A;  3GTQ A;  3IR5 A;  2Y0S A;  1ZYR D;  2G6G A;  4RV0 A;  5T5M D;  2B63 A;  3GTM A;  3TM7 B;  2V45 A;  3X2G A;  1WC2 A;  3SUJ A;  2O5J D;  4D7Z B;  2WB1 A;  2PIC A;  4KOD A;  2JIO A;  3X2J A;  2GAE A;  4QIW A;  2A68 D;  3QWZ A;  2NVY A;  1IW7 D;  1Y1V A;  1Y4Z A;  2WAQ A;  5FTK A;  3ML1 A;  4KDI A;  3X2P A;  1BW4 A;  1H5N A; 
#chains in the Genus database with same CATH homology
 1R27 A;  1TWH A;  3GTK A;  2JA6 A;  3QC8 A;  4AAY A;  3IR7 A;  2NYA A;  4AZD A;  3CZB A;  1ZC1 A;  3PLX B;  1KQF A;  1YNJ D;  1TWA A;  3OUG A;  3HU1 A;  1H0H A;  5C1B A;  2NVX A;  2A6E D;  4NOH A;  1Y5I A;  1E32 A;  2CW0 D;  3GTO A;  1PYU B;  3IR6 A;  3QQ8 A;  1QDN A;  2NAP A;  2VPW A;  1CZ4 A;  1DMR A;  4AON B;  2JIP A;  1SMY D;  1TWG A;  2PJH B;  2V3V A;  2A6H D;  2YUJ A;  3HU3 A;  2VPY A;  1WCM A;  2IV2 X;  4DMR A;  2DMR A;  2A69 D;  1SFO A;  2JA7 A;  2VPX A;  2PJJ A;  2KI8 A;  4CS0 A;  1Q16 A;  3HU2 A;  4AOK B;  4C2M A;  1Y1W A;  1E5V A;  2E2I A;  2VUM A;  3GTG A;  2YU9 A;  2R7Z A;  3FKI A;  2JIR A;  1UHD A;  3GTP A;  4CRY G;  4AYB A;  1PQF A;  1AA6 A;  2R92 A;  1TMO A;  1TWF A;  3TIW A;  3H0G A;  2G5D A;  2PI8 A;  1EU1 A;  1FDO A;  3CF2 A;  3O5A A;  5FTN A;  1R9T A;  1E60 A;  3QQ7 A;  1I50 A;  5DYG A;  1UHE A;  1PYQ A;  1PPY A;  1SIW A;  4KO8 A;  2AE0 X;  5EPP A;  1I3Q A;  2EEO B;  1G8J A;  4GA5 A;  1AW8 B;  1QCS A;  1PT0 A;  1YNN D;  2E7Z A;  4KLN A;  5FTL A;  5FTM A;  2PNW A;  3GTL A;  5DYI A;  2JIQ A;  2BE5 D;  2R93 A;  1WLF A;  2C45 A;  2JIM A;  1CR5 A;  2E2H A;  2VPZ A;  4CRZ A;  2JA5 A;  5C18 A;  1R7R A;  1VC3 B;  1KQG A;  5B6C A;  1YLE A;  2PMZ A;  1PT1 A;  1DMS A;  1OGY A;  3CQZ A;  1G8K A;  5GLF A;  1PQE A;  1S3S A;  3DMR A;  4GA6 A;  1PQH A;  3HKZ A;  4KDL A;  1CZ5 A;  1E61 A;  3GTJ A;  1K83 A;  5T5I D;  5FTJ A;  1TWC A;  1FDI A;  1E18 A;  3GTQ A;  3IR5 A;  2Y0S A;  1ZYR D;  2G6G A;  4RV0 A;  5T5M D;  2B63 A;  3GTM A;  3TM7 B;  2V45 A;  2O5J D;  4D7Z B;  2WB1 A;  2PIC A;  4KOD A;  2JIO A;  2GAE A;  4QIW A;  2A68 D;  3QWZ A;  2NVY A;  1IW7 D;  1Y1V A;  1Y4Z A;  2WAQ A;  5FTK A;  3ML1 A;  4KDI A;  1H5N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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