1PQHA

Serine 25 to threonine mutation of aspartate decarboxylase
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
118
Chain Sequence
RGSMIRTMLQGKLHRVKVTHADLHYEGTCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords Aspartate 1-decarboxylase
total genus 33
structure length 118
sequence length 119
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqhA00
4DMRA 1OGYA 1G8KA 1H0HA 2NYAA 1PT0A 3GTLA 1R7RA 1KQGA 5EPPA 3CQZA 2R93A 1QCSA 3GTMA 1YLEA 3HU3A 3O5AA 2JIMA 4RV0A 1EU1A 5FTNA 2E2HA 1CZ5A 2WAQA 4AZDA 3GTPA 4KLNA 4KDLA 1DMRA 2V45A 2VPYA 2E2IA 4AOKB 2JIPA 1WLFA 3QQ7A 1S3SA 1SFOA 1TWHA 3PLXB 4AONB 2E7ZA 1PQEA 2JIOA 3GTOA 4C2MA 3H0GA 1K83A 3HKZA 1E32A 1H5NA 4KDIA 5GLFA 1QDNA 3HU2A 3FKIA 1DMSA 1Y1WA 1SIWA 1TWGA 2JIRA 1E18A 3IR7A 4CS0A 1PYUB 3QQ8A 1PT1A 5B6CA 1Y1VA 1Q16A 3QC8A 1R27A 2EEOB 2PMZA 3DMRA 4AAYA 2R7ZA 3CF2A 5T5ID 3HU1A 3IR6A 1E61A 4CRYG 1PPYA 1AA6A 2VPXA 1TMOA 1UHDA 3GTJA 4GA6A 5FTMA 2PJHB 3ML1A 1FDIA 2DMRA 1CR5A 2WB1A 2NAPA 2VPZA 2VUMA 1R9TA 1I50A 1TWCA 1CZ4A 5C18A 1G8JA 2VPWA 3OUGA 1PQHA 2KI8A 1Y5IA 5FTKA 2NVYA 5DYGA 2R92A 4D7ZB 5C1BA 4QIWA 5DYIA 1TWFA 1WCMA 2NVXA 2Y0SA 1I3QA 2V3VA 1AW8B 3GTQA 2JA7A 1FDOA 3TIWA 3GTGA 3IR5A 1PQFA 1Y4ZA 2YU9A 4CRZA 4KODA 1KQFA 2IV2X 1E60A 2B63A 3TM7B 1TWAA 2C45A 5T5MD 5FTLA 2JA6A 1VC3B 5FTJA 3GTKA 4AYBA 1IW7D 1E5VA 1PYQA 3QWZA 4GA5A 2JA5A 2JIQA 1UHEA 4KO8A
chains in the Genus database with same CATH superfamily
3SUJA 4DMRA 3SUMA 1OGYA 1G8KA 1H0HA 2NYAA 1PT0A 3GTLA 1R7RA 1KQGA 5EPPA 2HCZX 3CQZA 2R93A 1QCSA 2A68D 1YLEA 3SULA 3GTMA 3HU3A 4NOHA 3O5AA 2JIMA 4RV0A 1EU1A 5FTNA 5GLXA 2E2HA 2PI8A 1CZ5A 2WAQA 4AZDA 3GTPA 4JP6A 4KLNA 4KDLA 1DMRA 2GAEA 2V45A 2VPYA 4ZM7A 2E2IA 4AOKB 2JIPA 1WLFA 3QQ7A 1S3SA 3X2HA 1SFOA 1TWHA 3PLXB 4AONB 2E7ZA 1PQEA 2JIOA 3GTOA 4C2MA 3H0GA 4FFTA 1K83A 3HKZA 1E32A 1H5NA 2KQAA 4KDIA 4JS7A 5GLFA 1QDNA 4FG2A 5GLYA 3HU2A 3FKIA 4JP7A 1DMSA 1Y1WA 1SIWA 1TWGA 2JIRA 2A6ED 2CW0D 1E18A 3IR7A 4CS0A 1PYUB 3QQ8A 4JJOA 2O5JD 1PT1A 5B6CA 1Y1VA 1Q16A 3QC8A 3X2GA 1R27A 2EEOB 2PJJA 1ZYRD 2PMZA 3DMRA 4AAYA 1ZC1A 3CF2A 2R7ZA 5T5ID 3HU1A 3IR6A 1E61A 4CRYG 1PPYA 1AA6A 1OA7A 1BW3A 4FG4A 2VPXA 1TMOA 2G5DA 2PICA 1UHDA 3GTJA 3X2NA 4GA6A 5FTMA 1N10A 2PJHB 3ML1A 2BH0A 3X2LA 1FDIA 5H4UA 2DMRA 1CR5A 5GM9A 3ENGA 2WB1A 2NAPA 2VPZA 2VUMA 1R9TA 1L8FA 1I50A 3X2IA 1TWCA 3D30A 1CZ4A 5C18A 1G8JA 2VPWA 3OUGA 1PQHA 2KI8A 1Y5IA 5FTKA 4L48A 2NVYA 5DYGA 2R92A 4D7ZB 1HD5A 4QIWA 5DYIA 1TWFA 1WCMA 3M3GA 5C1BA 2NVXA 3X2OA 2Y0SA 1I3QA 2V3VA 4AVRA 3X2KA 1AW8B 2A6HD 3GTQA 1FDOA 2JA7A 4FERA 4ENGA 3TIWA 3GTGA 3IR5A 1PQFA 2BE5D 1Y4ZA 4CRZA 2YU9A 1BW4A 4KODA 2PNWA 2ENGA 1KQFA 1YNJD 2IV2X 1YNND 1E60A 2B63A 3TM7B 1TWAA 2C45A 5T5MD 5FTLA 2JA6A 3X2PA 3X2MA 1VC3B 2A69D 5FTJA 3GTKA 4AYBA 2G6GA 1IW7D 3SUKA 3X2JA 1E5VA 1PYQA 4JCWA 2AE0X 3CZBA 1OA9A 3QWZA 1WC2A 4GA5A 2YUJA 2JA5A 2JIQA 1SMYD 1UHEA 4KO8A
chains in the Genus database with same CATH topology
4DMRA 1OGYA 1G8KA 1H0HA 2NYAA 1PT0A 3GTLA 1R7RA 1KQGA 5EPPA 3CQZA 2R93A 1QCSA 2A68D 1YLEA 3GTMA 3HU3A 4NOHA 3O5AA 2JIMA 4RV0A 1EU1A 5FTNA 2E2HA 2PI8A 1CZ5A 2WAQA 4AZDA 3GTPA 4KLNA 4KDLA 1DMRA 2GAEA 2V45A 2VPYA 2E2IA 4AOKB 2JIPA 1WLFA 3QQ7A 1S3SA 1SFOA 1TWHA 3PLXB 4AONB 2E7ZA 1PQEA 2JIOA 3GTOA 4C2MA 3H0GA 1K83A 3HKZA 1E32A 1H5NA 4KDIA 5GLFA 1QDNA 3HU2A 3FKIA 1DMSA 1Y1WA 1SIWA 1TWGA 2JIRA 2A6ED 2CW0D 1E18A 3IR7A 4CS0A 1PYUB 3QQ8A 2O5JD 1PT1A 5B6CA 1Y1VA 1Q16A 3QC8A 1R27A 2EEOB 2PJJA 1ZYRD 2PMZA 3DMRA 4AAYA 1ZC1A 3CF2A 2R7ZA 5T5ID 3HU1A 3IR6A 1E61A 4CRYG 1PPYA 1AA6A 2VPXA 1TMOA 2G5DA 2PICA 1UHDA 3GTJA 4GA6A 5FTMA 2PJHB 3ML1A 1FDIA 2DMRA 1CR5A 2WB1A 2NAPA 2VPZA 2VUMA 1R9TA 1I50A 1TWCA 1CZ4A 5C18A 1G8JA 2VPWA 3OUGA 1PQHA 2KI8A 1Y5IA 5FTKA 2NVYA 5DYGA 2R92A 4D7ZB 5C1BA 4QIWA 5DYIA 1TWFA 1WCMA 2NVXA 2Y0SA 1I3QA 2V3VA 1AW8B 2A6HD 3GTQA 1FDOA 2JA7A 3TIWA 3GTGA 3IR5A 1PQFA 2BE5D 1Y4ZA 4CRZA 2YU9A 4KODA 2PNWA 1KQFA 1YNJD 2IV2X 1YNND 1E60A 2B63A 3TM7B 1TWAA 2C45A 5T5MD 5FTLA 2JA6A 1VC3B 2A69D 5FTJA 3GTKA 4AYBA 2G6GA 1IW7D 1E5VA 1PYQA 2AE0X 3CZBA 3QWZA 4GA5A 2YUJA 2JA5A 2JIQA 1SMYD 1UHEA 4KO8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DMR A;  1OGY A;  1G8K A;  1H0H A;  2NYA A;  1PT0 A;  3GTL A;  1R7R A;  1KQG A;  5EPP A;  3CQZ A;  2R93 A;  1QCS A;  3GTM A;  1YLE A;  3HU3 A;  3O5A A;  2JIM A;  4RV0 A;  1EU1 A;  5FTN A;  2E2H A;  1CZ5 A;  2WAQ A;  4AZD A;  3GTP A;  4KLN A;  4KDL A;  1DMR A;  2V45 A;  2VPY A;  2E2I A;  4AOK B;  2JIP A;  1WLF A;  3QQ7 A;  1S3S A;  1SFO A;  1TWH A;  3PLX B;  4AON B;  2E7Z A;  1PQE A;  2JIO A;  3GTO A;  4C2M A;  3H0G A;  1K83 A;  3HKZ A;  1E32 A;  1H5N A;  4KDI A;  5GLF A;  1QDN A;  3HU2 A;  3FKI A;  1DMS A;  1Y1W A;  1SIW A;  1TWG A;  2JIR A;  1E18 A;  3IR7 A;  4CS0 A;  1PYU B;  3QQ8 A;  1PT1 A;  5B6C A;  1Y1V A;  1Q16 A;  3QC8 A;  1R27 A;  2EEO B;  2PMZ A;  3DMR A;  4AAY A;  2R7Z A;  3CF2 A;  5T5I D;  3HU1 A;  3IR6 A;  1E61 A;  4CRY G;  1PPY A;  1AA6 A;  2VPX A;  1TMO A;  1UHD A;  3GTJ A;  4GA6 A;  5FTM A;  2PJH B;  3ML1 A;  1FDI A;  2DMR A;  1CR5 A;  2WB1 A;  2NAP A;  2VPZ A;  2VUM A;  1R9T A;  1I50 A;  1TWC A;  1CZ4 A;  5C18 A;  1G8J A;  2VPW A;  3OUG A;  1PQH A;  2KI8 A;  1Y5I A;  5FTK A;  2NVY A;  5DYG A;  2R92 A;  4D7Z B;  5C1B A;  4QIW A;  5DYI A;  1TWF A;  1WCM A;  2NVX A;  2Y0S A;  1I3Q A;  2V3V A;  1AW8 B;  3GTQ A;  2JA7 A;  1FDO A;  3TIW A;  3GTG A;  3IR5 A;  1PQF A;  1Y4Z A;  2YU9 A;  4CRZ A;  4KOD A;  1KQF A;  2IV2 X;  1E60 A;  2B63 A;  3TM7 B;  1TWA A;  2C45 A;  5T5M D;  5FTL A;  2JA6 A;  1VC3 B;  5FTJ A;  3GTK A;  4AYB A;  1IW7 D;  1E5V A;  1PYQ A;  3QWZ A;  4GA5 A;  2JA5 A;  2JIQ A;  1UHE A;  4KO8 A; 
#chains in the Genus database with same CATH topology
 3SUJ A;  4DMR A;  3SUM A;  1OGY A;  1G8K A;  1H0H A;  2NYA A;  1PT0 A;  3GTL A;  1R7R A;  1KQG A;  5EPP A;  2HCZ X;  3CQZ A;  2R93 A;  1QCS A;  2A68 D;  1YLE A;  3SUL A;  3GTM A;  3HU3 A;  4NOH A;  3O5A A;  2JIM A;  4RV0 A;  1EU1 A;  5FTN A;  5GLX A;  2E2H A;  2PI8 A;  1CZ5 A;  2WAQ A;  4AZD A;  3GTP A;  4JP6 A;  4KLN A;  4KDL A;  1DMR A;  2GAE A;  2V45 A;  2VPY A;  4ZM7 A;  2E2I A;  4AOK B;  2JIP A;  1WLF A;  3QQ7 A;  1S3S A;  3X2H A;  1SFO A;  1TWH A;  3PLX B;  4AON B;  2E7Z A;  1PQE A;  2JIO A;  3GTO A;  4C2M A;  3H0G A;  4FFT A;  1K83 A;  3HKZ A;  1E32 A;  1H5N A;  2KQA A;  4KDI A;  4JS7 A;  5GLF A;  1QDN A;  4FG2 A;  5GLY A;  3HU2 A;  3FKI A;  4JP7 A;  1DMS A;  1Y1W A;  1SIW A;  1TWG A;  2JIR A;  2A6E D;  2CW0 D;  1E18 A;  3IR7 A;  4CS0 A;  1PYU B;  3QQ8 A;  4JJO A;  2O5J D;  1PT1 A;  5B6C A;  1Y1V A;  1Q16 A;  3QC8 A;  3X2G A;  1R27 A;  2EEO B;  2PJJ A;  1ZYR D;  2PMZ A;  3DMR A;  4AAY A;  1ZC1 A;  3CF2 A;  2R7Z A;  5T5I D;  3HU1 A;  3IR6 A;  1E61 A;  4CRY G;  1PPY A;  1AA6 A;  1OA7 A;  1BW3 A;  4FG4 A;  2VPX A;  1TMO A;  2G5D A;  2PIC A;  1UHD A;  3GTJ A;  3X2N A;  4GA6 A;  5FTM A;  1N10 A;  2PJH B;  3ML1 A;  2BH0 A;  3X2L A;  1FDI A;  5H4U A;  2DMR A;  1CR5 A;  5GM9 A;  3ENG A;  2WB1 A;  2NAP A;  2VPZ A;  2VUM A;  1R9T A;  1L8F A;  1I50 A;  3X2I A;  1TWC A;  3D30 A;  1CZ4 A;  5C18 A;  1G8J A;  2VPW A;  3OUG A;  1PQH A;  2KI8 A;  1Y5I A;  5FTK A;  4L48 A;  2NVY A;  5DYG A;  2R92 A;  4D7Z B;  1HD5 A;  4QIW A;  5DYI A;  1TWF A;  1WCM A;  3M3G A;  5C1B A;  2NVX A;  3X2O A;  2Y0S A;  1I3Q A;  2V3V A;  4AVR A;  3X2K A;  1AW8 B;  2A6H D;  3GTQ A;  1FDO A;  2JA7 A;  4FER A;  4ENG A;  3TIW A;  3GTG A;  3IR5 A;  1PQF A;  2BE5 D;  1Y4Z A;  4CRZ A;  2YU9 A;  1BW4 A;  4KOD A;  2PNW A;  2ENG A;  1KQF A;  1YNJ D;  2IV2 X;  1YNN D;  1E60 A;  2B63 A;  3TM7 B;  1TWA A;  2C45 A;  5T5M D;  5FTL A;  2JA6 A;  3X2P A;  3X2M A;  1VC3 B;  2A69 D;  5FTJ A;  3GTK A;  4AYB A;  2G6G A;  1IW7 D;  3SUK A;  3X2J A;  1E5V A;  1PYQ A;  4JCW A;  2AE0 X;  3CZB A;  1OA9 A;  3QWZ A;  1WC2 A;  4GA5 A;  2YUJ A;  2JA5 A;  2JIQ A;  1SMY D;  1UHE A;  4KO8 A; 
#chains in the Genus database with same CATH homology
 4DMR A;  1OGY A;  1G8K A;  1H0H A;  2NYA A;  1PT0 A;  3GTL A;  1R7R A;  1KQG A;  5EPP A;  3CQZ A;  2R93 A;  1QCS A;  2A68 D;  1YLE A;  3GTM A;  3HU3 A;  4NOH A;  3O5A A;  2JIM A;  4RV0 A;  1EU1 A;  5FTN A;  2E2H A;  2PI8 A;  1CZ5 A;  2WAQ A;  4AZD A;  3GTP A;  4KLN A;  4KDL A;  1DMR A;  2GAE A;  2V45 A;  2VPY A;  2E2I A;  4AOK B;  2JIP A;  1WLF A;  3QQ7 A;  1S3S A;  1SFO A;  1TWH A;  3PLX B;  4AON B;  2E7Z A;  1PQE A;  2JIO A;  3GTO A;  4C2M A;  3H0G A;  1K83 A;  3HKZ A;  1E32 A;  1H5N A;  4KDI A;  5GLF A;  1QDN A;  3HU2 A;  3FKI A;  1DMS A;  1Y1W A;  1SIW A;  1TWG A;  2JIR A;  2A6E D;  2CW0 D;  1E18 A;  3IR7 A;  4CS0 A;  1PYU B;  3QQ8 A;  2O5J D;  1PT1 A;  5B6C A;  1Y1V A;  1Q16 A;  3QC8 A;  1R27 A;  2EEO B;  2PJJ A;  1ZYR D;  2PMZ A;  3DMR A;  4AAY A;  1ZC1 A;  3CF2 A;  2R7Z A;  5T5I D;  3HU1 A;  3IR6 A;  1E61 A;  4CRY G;  1PPY A;  1AA6 A;  2VPX A;  1TMO A;  2G5D A;  2PIC A;  1UHD A;  3GTJ A;  4GA6 A;  5FTM A;  2PJH B;  3ML1 A;  1FDI A;  2DMR A;  1CR5 A;  2WB1 A;  2NAP A;  2VPZ A;  2VUM A;  1R9T A;  1I50 A;  1TWC A;  1CZ4 A;  5C18 A;  1G8J A;  2VPW A;  3OUG A;  1PQH A;  2KI8 A;  1Y5I A;  5FTK A;  2NVY A;  5DYG A;  2R92 A;  4D7Z B;  5C1B A;  4QIW A;  5DYI A;  1TWF A;  1WCM A;  2NVX A;  2Y0S A;  1I3Q A;  2V3V A;  1AW8 B;  2A6H D;  3GTQ A;  1FDO A;  2JA7 A;  3TIW A;  3GTG A;  3IR5 A;  1PQF A;  2BE5 D;  1Y4Z A;  4CRZ A;  2YU9 A;  4KOD A;  2PNW A;  1KQF A;  1YNJ D;  2IV2 X;  1YNN D;  1E60 A;  2B63 A;  3TM7 B;  1TWA A;  2C45 A;  5T5M D;  5FTL A;  2JA6 A;  1VC3 B;  2A69 D;  5FTJ A;  3GTK A;  4AYB A;  2G6G A;  1IW7 D;  1E5V A;  1PYQ A;  2AE0 X;  3CZB A;  3QWZ A;  4GA5 A;  2YUJ A;  2JA5 A;  2JIQ A;  1SMY D;  1UHE A;  4KO8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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