1WU1B

Factor xa in complex with the inhibitor 4-[(5-chloroindol-2-yl)sulfonyl]-2-(2-methylpropyl)-1-[[5-(pyridin-4-yl) pyrimidin-2-yl]carbonyl]piperazine
Total Genus 11
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
54
structure length
54
Chain Sequence
TRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Coagulation factor X, heavy chain
total genus 11
structure length 54
sequence length 54
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2004-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00008 EGF EGF-like domain
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1wu1B00
1EQGA 2VWOL 1N1IA 4LMFA 1KSNB 1F7EA 2WPKE 1IQKL 3ELAL 4Y7AB 4BDWA 2YGOA 2P16L 2Y38A 4BXWA 2FLRL 3SW2A 2WYJB 1KLJL 3HS5A 1YUKB 5L2YL 1HJ7A 3KQEL 5KIRA 1KIGL 3BT2A 1V3XB 3IJEB 3V64C 2Y81B 1J9CL 2MGRA 2FZZL 4ZH8B 4D0FA 3M37L 2XBYL 3ZYIB 3F1SB 1UZPA 3P5BL 4NG9L 1FSBA 5CKMA 1IQIL 2W86A 4YT6L 5JBAE 3HS7A 2UWLB 2XBXL 2P3FN 1CQEA 1HAEA 3Q3KB 1K37A 5JVYA 1IOEL 3R05A 5JB9E 3OLTA 1YO8A 1CEJA 2UWPB 2RA0L 3CENL 4Y79B 1F7MA 4JYUL 1CCVA 4OTJA 2I9AA 1IP0A 1U67A 3OLUA 2BMGA 2PR3B 4D90A 2J4IB 5COXA 3SOBB 4O1ZA 3U73A 3NTGA 3H5CB 4RRWA 1FE2A 1IVOC 5EGMB 2DDUA 3SOVA 1G2MB 1IQHL 1L5GB 1DX5I 1XFEA 2PHBB 1DQBA 2BZ6L 2CJIB 1NPEB 4CSYA 1W7XL 3KRKA 1EAIC 2VWMK 3N8YA 4A7IA 2WPME 3LN0A 3N8ZA 1TLEA 3FFGL 4BDXA 1HAFA 2XBWL 2JKHL 3KCGL 4CUFA 3N8WA 3TBDA 1N7DA 3KL6B 1G1SA 3NT1A 2P26A 1EBVA 3ZYGA 5F19A 1HREA 4CUEA 4NA9L 1EQHA 2Y5GL 2P28B 2Y5FL 2XBVL 4PH9A 2W26B 5F1AA 1Q4GA 2VWLL 1XDTR 3HS6A 4ZHAB 2Q1JB 3GISX 5L30L 3NJPC 4ZAEB 5I46L 1AUTL 1SZBA 2KL7A 4Y6DB 1XKBA 1WHFA 4O02B 3KK6A 1NFXB 1IQEL 1XKAL 1FFMA 2BOKL 1MQ5L 1IJQA 1ATEA 2J34B 1PXXA 4CUDA 5KN5C 2MHPA 4Y7BB 4ZXXL 1ATDA 1NFUB 2W3KB 1FAXL 4D0EA 4YZUB 4G1MB 2Y5HL 5CKQA 1TOZA 3LC3B 2K2TA 3N8XA 1NQLB 4X8UL 1EMOA 2FLGA 4XBMA 1C5MF 1P0SL 1HZ8A 1U8CB 5CKNA 2BQ6A 1EPGA 3ZYJB 1X7AL 4RRZA 3C9AC 4XL1A 1TPGA 1DDXA 1LQDA 3QMOA 1HX2A 2GD4A 2J94B 5L2ZL 1IGXA 1JV2B 1EPIA 1NFYB 1COUA 1EPHA 4BTUA 2P3FL 1EMNA 1K36A 1DVAL 3LC5B 1ATBA 5IKTA 1JBUL 4AQTA 1L3YA 3N8VA 1IQFL 1HRFA 2WFTA 3KQBL 5E8DA 1HT8A 2K2SB 2W2PE 5IKVA 2BOUA 2RHPA 2P3UA 3CFWA 2YGPA 2AYLA 1KLOA 1IQJL 1CVWL 2P94L 3TGFA 1I0UA 2KB9A 1YUGA 6COXA 2PUQL 2EI7B 1O5DL 3IITB 1NT0A 1G1QA 4RUTA 2ADXA 3RR3A 1APOA 1YUFA 1JL9A 1LPKA 2Y80B 1OB1C 3N8WB 4ISHL 2XC5L 2VVVL 2W2OE 3BPSE 2MGPA 1EZQB 3V65B 2VVUL 2J38B 1HCGB 2FLBL 2W2ME 2XC4L 2VWNL 2Y7ZB 5JVZA 2WPJE 1ATAA 1IQNL 3BT1A 1IOXA 1BF9A 3LTGD 4YT7L 1LMJA 1YGCL 1QFKL 2EI8B 1FAKL 1ZAQA 4OTYA 2W3IB 2WYGB 3HPTA 4BTTA 1M1XB 3K9XA 4M11A 1F0SB 4C16A 4JZDL 1B9WA 3ASIA 2I9BA 2VJ3A 2VH0B 3HO4A 4ZXYL 3NTBA 2OYEP 4X8VL 1PRHA 4RRYA 4MMXB 1WHEA 2P3TA 3FCSB 3TK6B 1LPGA 2BO2A 3MDLA 1UZKA 3TZIA 1CCFA 2Y82B 5JW1A 3FBYA 2J2UB 3GCWE 3TK5B 1RFNB 2W2QE 3SOQA 1APQA 3DEMA 1PTHA 3QH0A 2WPLE 1ADXA 2WPIE 4Z0KB 3QCWA 4ISIL 2M74A 5JBCE 1IQGL 2RNLA 2KV4A 1EGFA 2H9EL 4LORA 4Z0LA 5JB8E 4MMZB 1URKA 1F0RB 1HT5A 3LIWB 5IKQA 4E1GA 4X8SL 3U7UG 1PGEA 2WG3C 3M36L 3ENSA 2VH6B 4FM5A 1P9JA 2NPRA 3CS7L 2BOHA 2W2NE 3GCXE 1FJSL 1IQLL 1IGZA 3EGFA 1MOXC 4JYVL 4TGFA 5JBBE 4JZEL 2WFXB 2P95L 2VVCK 2BOXA 3F6UL 4BTIA 3LN1A 1G2LB 1FF7A 4JZFL 3Q7DA 4X8TL 3MQEA 4RRXA 1UZQA 4Y71B 3N8YB 1G1TA 2J95B 1GK5A 3LAQA 1CX2A 1WU1B 3KQDL 5K0HB 1G1RA 1KLIL 2WPHE 1Z6CA 2FD6A 3HO3A 1Z6EL 1LPZA 3POYA 2P93L 4Y76B 2F9BL 2XC0L 3TH3L 1IQML 2TGFA 2B7DL 4COXA 1A3PA 1NZIA 4RS0A 4NGAL 2BQ7A 1NFWB 5CISA 1DIYA 3CA7A 4M10A 1UZJA 2Y7XB 2BQWA 2UWOB 2WG4B 3PGHA 5FDQA 3HO5A 4XLWA 4MMYB 4Z6AL 1PFXL 3KQCL 2EI6B 3LTFB 4BXSA 2D1JB 1CVUA 2G00L 2OYUP 1MQ6L 1EPJA 5IKRA 1W8BL
chains in the Genus database with same CATH superfamily
1EQGA 2VWOL 1N1IA 4LMFA 1KSNB 1F7EA 2WPKE 1IQKL 3ELAL 4Y7AB 4BDWA 2YGOA 1V1IA 2P16L 2Y38A 4BXWA 2FLRL 4GU3A 3SW2A 2WYJB 1KLJL 3HS5A 1YUKB 5L2YL 1KKEA 3KQEL 1HJ7A 5KIRA 1KIGL 3BT2A 1V3XB 3IJEB 3V64C 2Y81B 2YGQA 1J9CL 2MGRA 2FZZL 4ZH8B 4D0FA 3M37L 2XBYL 3ZYIB 2BT8A 3F1SB 1UZPA 3P5BL 4NG9L 1FSBA 5CKMA 1IQIL 2W86A 4YT6L 5JBAE 3HS7A 1LK9A 2UWLB 2XBXL 2P3FN 1CQEA 1HAEA 3Q3KB 1K37A 5JVYA 1IOEL 3R05A 5JB9E 3OLTA 1YO8A 1CEJA 2UWPB 2RA0L 3CENL 4Y79B 1F7MA 4JYUL 1CCVA 4OTJA 2I9AA 2JJLA 1IP0A 1U67A 3OLUA 2BMGA 2PR3B 4D90A 2J4IB 5COXA 3SOBB 4O1ZA 3U73A 3NTGA 3H5CB 4RRWA 1FE2A 1IVOC 5EGMB 2DDUA 3SOVA 1G2MB 1IQHL 1L5GB 1DX5I 1XFEA 2PHBB 1DQBA 2BZ6L 2CJIB 1NPEB 4CSYA 1W7XL 3KRKA 1EAIC 2VWMK 3N8YA 4A7IA 2WPME 3LN0A 3N8ZA 1TLEA 3FFGL 4BDXA 1HAFA 2XBWL 2JKHL 3KCGL 4CUFA 3N8WA 3TBDA 1N7DA 3KL6B 1G1SA 3NT1A 2P26A 2BT7A 1EBVA 3ZYGA 5F19A 1HREA 4CUEA 4NA9L 1EQHA 2Y5GL 2P28B 2Y5FL 2XBVL 4PH9A 2W26B 5F1AA 1Q4GA 2VWLL 1XDTR 3HS6A 4ZHAB 2Q1JB 3GISX 5L30L 3NJPC 4ZAEB 5I46L 1AUTL 1SZBA 2KL7A 4Y6DB 1XKBA 1WHFA 4O02B 3KK6A 1NFXB 1IQEL 1XKAL 1FFMA 2BOKL 1MQ5L 1IJQA 1ATEA 2J34B 1PXXA 4CUDA 5KN5C 1LMMA 2MHPA 4Y7BB 4ZXXL 1ATDA 1NFUB 2W3KB 1FAXL 4D0EA 4YZUB 4G1MB 2Y5HL 5CKQA 1TOZA 3LC3B 2K2TA 3N8XA 1NQLB 4X8UL 1EMOA 2FLGA 4XBMA 1C5MF 1P0SL 1HZ8A 1U8CB 5CKNA 2BQ6A 1EPGA 3ZYJB 1X7AL 4RRZA 3C9AC 4XL1A 1TPGA 1DDXA 1LQDA 3QMOA 1HX2A 2GD4A 2J94B 5L2ZL 1IGXA 1JV2B 1EPIA 1NFYB 1COUA 1EPHA 4BTUA 2P3FL 1EMNA 2BSFA 3S6XA 1K36A 1DVAL 3LC5B 1ATBA 5IKTA 1JBUL 4AQTA 1L3YA 3N8VA 1IQFL 1HRFA 2WFTA 3KQBL 5E8DA 1HT8A 2K2SB 2W2PE 5IKVA 2BOUA 2RHPA 2P3UA 3CFWA 2YGPA 2AYLA 1KLOA 1IQJL 1CVWL 2P94L 3TGFA 1I0UA 2KB9A 1YUGA 6COXA 2PUQL 2EI7B 1O5DL 3IITB 1NT0A 1G1QA 4RUTA 2ADXA 3RR3A 2VRSA 1APOA 1YUFA 1JL9A 1LPKA 2Y80B 1OB1C 3N8WB 4ISHL 2XC5L 2VVVL 2W2OE 3BPSE 2MGPA 1EZQB 3V65B 2VVUL 2J38B 1HCGB 2FLBL 2W2ME 2XC4L 2VWNL 2Y7ZB 5JVZA 2WPJE 1ATAA 1IQNL 3BT1A 1IOXA 1BF9A 3LTGD 4YT7L 1LMJA 1YGCL 1QFKL 2EI8B 1FAKL 1ZAQA 4OTYA 2W3IB 2WYGB 3HPTA 4BTTA 1M1XB 3K9XA 4M11A 1F0SB 4C16A 4JZDL 1B9WA 3ASIA 2I9BA 2VJ3A 2VH0B 3HO4A 4ZXYL 3NTBA 2OYEP 4X8VL 1PRHA 4RRYA 4MMXB 1WHEA 2P3TA 3FCSB 3TK6B 1LPGA 2BO2A 3MDLA 1UZKA 3TZIA 1CCFA 2Y82B 5JW1A 3FBYA 2J2UB 3GCWE 3TK5B 1RFNB 2W2QE 3SOQA 1APQA 3DEMA 1PTHA 3QH0A 2WPLE 1ADXA 2WPIE 4Z0KB 3QCWA 4ISIL 2M74A 5JBCE 1IQGL 2RNLA 2KV4A 1EGFA 2H9EL 4LORA 4Z0LA 5JB8E 4MMZB 1URKA 1F0RB 1HT5A 1QIUA 3LIWB 2HOXA 4E1GA 5IKQA 4X8SL 3U7UG 1PGEA 2WG3C 3M36L 3ENSA 2VH6B 4FM5A 1P9JA 2NPRA 3CS7L 2BOHA 2W2NE 3GCXE 1FJSL 1IQLL 1IGZA 3EGFA 1MOXC 2H9EC 2HORA 4JYVL 1V1HA 4TGFA 5JBBE 4JZEL 2WFXB 2P95L 2VVCK 2BOXA 3F6UL 4BTIA 3LN1A 1G2LB 1FF7A 4JZFL 3Q7DA 4X8TL 3MQEA 4RRXA 1UZQA 4Y71B 3N8YB 2WZPP 1G1TA 2J95B 1GK5A 4A94C 3LAQA 1CX2A 1WU1B 3KQDL 5K0HB 1G1RA 1KLIL 2WPHE 1Z6CA 2FD6A 3HO3A 1Z6EL 1LPZA 3POYA 2P93L 4Y76B 2F9BL 2XC0L 3TH3L 1IQML 2TGFA 2B7DL 4COXA 1A3PA 1NZIA 4RS0A 4NGAL 2BQ7A 1NFWB 5CISA 1DIYA 3CA7A 4M10A 1UZJA 2Y7XB 2KNIA 2BQWA 2UWOB 2WG4B 3PGHA 5FDQA 3HO5A 4XLWA 4MMYB 4Z6AL 1PFXL 3KQCL 2EI6B 3LTFB 4BXSA 4GU4A 2D1JB 1CVUA 2G00L 2OYUP 1MQ6L 1EPJA 5IKRA 1W8BL
chains in the Genus database with same CATH topology
1EQGA 2VWOL 1N1IA 4LMFA 1KSNB 1F7EA 2WPKE 1IQKL 3ELAL 4Y7AB 4BDWA 2YGOA 2P16L 2Y38A 4BXWA 2FLRL 3SW2A 2WYJB 1KLJL 3HS5A 1YUKB 5L2YL 1HJ7A 3KQEL 5KIRA 1KIGL 3BT2A 1V3XB 3IJEB 3V64C 2Y81B 2YGQA 1J9CL 2MGRA 2FZZL 4ZH8B 4D0FA 3M37L 2XBYL 3ZYIB 3F1SB 1UZPA 3P5BL 4NG9L 1FSBA 5CKMA 1IQIL 2W86A 4YT6L 5JBAE 3HS7A 2UWLB 2XBXL 2P3FN 1CQEA 1HAEA 3Q3KB 1K37A 5JVYA 1IOEL 3R05A 5JB9E 3OLTA 1YO8A 1CEJA 2UWPB 2RA0L 3CENL 4Y79B 1F7MA 4JYUL 1CCVA 4OTJA 2I9AA 1IP0A 1U67A 3OLUA 2BMGA 2PR3B 4D90A 2J4IB 5COXA 3SOBB 4O1ZA 3U73A 3NTGA 3H5CB 4RRWA 1FE2A 1IVOC 5EGMB 2DDUA 3SOVA 1G2MB 1IQHL 1L5GB 1DX5I 1XFEA 2PHBB 1DQBA 2BZ6L 2CJIB 1NPEB 4CSYA 1W7XL 3KRKA 1EAIC 2VWMK 3N8YA 4A7IA 2WPME 3LN0A 3N8ZA 1TLEA 3FFGL 4BDXA 1HAFA 2XBWL 2JKHL 3KCGL 4CUFA 3N8WA 3TBDA 1N7DA 3KL6B 1G1SA 3NT1A 2P26A 1EBVA 3ZYGA 5F19A 1HREA 4CUEA 4NA9L 1EQHA 2Y5GL 2P28B 2Y5FL 2XBVL 4PH9A 2W26B 5F1AA 1Q4GA 2VWLL 1XDTR 3HS6A 4ZHAB 2Q1JB 3GISX 5L30L 3NJPC 4ZAEB 5I46L 1AUTL 1SZBA 2KL7A 4Y6DB 1XKBA 1WHFA 4O02B 3KK6A 1NFXB 1IQEL 1XKAL 1FFMA 2BOKL 1MQ5L 1IJQA 1ATEA 2J34B 1PXXA 4CUDA 5KN5C 1LMMA 2MHPA 4Y7BB 4ZXXL 1ATDA 1NFUB 2W3KB 1FAXL 4D0EA 4YZUB 4G1MB 2Y5HL 5CKQA 1TOZA 3LC3B 2K2TA 3N8XA 1NQLB 4X8UL 1EMOA 2FLGA 4XBMA 1C5MF 1P0SL 1HZ8A 1U8CB 5CKNA 2BQ6A 1EPGA 3ZYJB 1X7AL 4RRZA 3C9AC 4XL1A 1TPGA 1DDXA 1LQDA 3QMOA 1HX2A 2GD4A 2J94B 5L2ZL 1IGXA 1JV2B 1EPIA 1NFYB 1COUA 1EPHA 4BTUA 2P3FL 1EMNA 3S6XA 1K36A 1DVAL 3LC5B 1ATBA 5IKTA 1JBUL 4AQTA 1L3YA 3N8VA 1IQFL 1HRFA 2WFTA 3KQBL 5E8DA 1HT8A 2K2SB 2W2PE 5IKVA 2BOUA 2RHPA 2P3UA 3CFWA 2YGPA 2AYLA 1KLOA 1IQJL 1CVWL 2P94L 3TGFA 1I0UA 2KB9A 1YUGA 6COXA 2PUQL 2EI7B 1O5DL 3IITB 1NT0A 1G1QA 4RUTA 2ADXA 3RR3A 1APOA 1YUFA 1JL9A 1LPKA 2Y80B 1OB1C 3N8WB 4ISHL 2XC5L 2VVVL 2W2OE 3BPSE 2MGPA 1EZQB 3V65B 2VVUL 2J38B 1HCGB 2FLBL 2W2ME 2XC4L 2VWNL 2Y7ZB 5JVZA 2WPJE 1ATAA 1IQNL 3BT1A 1IOXA 1BF9A 3LTGD 4YT7L 1LMJA 1YGCL 1QFKL 2EI8B 1FAKL 1ZAQA 4OTYA 2W3IB 2WYGB 3HPTA 4BTTA 1M1XB 3K9XA 4M11A 1F0SB 4C16A 4JZDL 1B9WA 3ASIA 2I9BA 2VJ3A 2VH0B 3HO4A 4ZXYL 3NTBA 2OYEP 4X8VL 1PRHA 4RRYA 4MMXB 1WHEA 2P3TA 3FCSB 3TK6B 1LPGA 2BO2A 3MDLA 1UZKA 3TZIA 1CCFA 2Y82B 5JW1A 3FBYA 2J2UB 3GCWE 3TK5B 1RFNB 2W2QE 3SOQA 1APQA 3DEMA 1PTHA 3QH0A 2WPLE 1ADXA 2WPIE 4Z0KB 3QCWA 4ISIL 2M74A 5JBCE 1IQGL 2RNLA 2KV4A 1EGFA 2H9EL 4LORA 4Z0LA 5JB8E 4MMZB 1URKA 1F0RB 1HT5A 3LIWB 5IKQA 4E1GA 4X8SL 3U7UG 1PGEA 2WG3C 3M36L 3ENSA 2VH6B 4FM5A 1P9JA 2NPRA 3CS7L 2BOHA 2W2NE 3GCXE 1FJSL 1IQLL 1IGZA 3EGFA 1MOXC 2H9EC 4JYVL 4TGFA 5JBBE 4JZEL 2WFXB 2P95L 2VVCK 2BOXA 3F6UL 4BTIA 3LN1A 1G2LB 1FF7A 4JZFL 3Q7DA 4X8TL 3MQEA 4RRXA 1UZQA 4Y71B 3N8YB 2WZPP 1G1TA 2J95B 1GK5A 4A94C 3LAQA 1CX2A 1WU1B 3KQDL 5K0HB 1G1RA 1KLIL 2WPHE 1Z6CA 2FD6A 3HO3A 1Z6EL 1LPZA 3POYA 2P93L 4Y76B 2F9BL 2XC0L 3TH3L 1IQML 2TGFA 2B7DL 4COXA 1A3PA 1NZIA 4RS0A 4NGAL 2BQ7A 1NFWB 5CISA 1DIYA 3CA7A 4M10A 1UZJA 2Y7XB 2KNIA 2BQWA 2UWOB 2WG4B 3PGHA 5FDQA 3HO5A 4XLWA 4MMYB 4Z6AL 1PFXL 3KQCL 2EI6B 3LTFB 4BXSA 2D1JB 1CVUA 2G00L 2OYUP 1MQ6L 1EPJA 5IKRA 1W8BL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EQG A;  2VWO L;  1N1I A;  4LMF A;  1KSN B;  1F7E A;  2WPK E;  1IQK L;  3ELA L;  4Y7A B;  4BDW A;  2YGO A;  2P16 L;  2Y38 A;  4BXW A;  2FLR L;  3SW2 A;  2WYJ B;  1KLJ L;  3HS5 A;  1YUK B;  5L2Y L;  1HJ7 A;  3KQE L;  5KIR A;  1KIG L;  3BT2 A;  1V3X B;  3IJE B;  3V64 C;  2Y81 B;  1J9C L;  2MGR A;  2FZZ L;  4ZH8 B;  4D0F A;  3M37 L;  2XBY L;  3ZYI B;  3F1S B;  1UZP A;  3P5B L;  4NG9 L;  1FSB A;  5CKM A;  1IQI L;  2W86 A;  4YT6 L;  5JBA E;  3HS7 A;  2UWL B;  2XBX L;  2P3F N;  1CQE A;  1HAE A;  3Q3K B;  1K37 A;  5JVY A;  1IOE L;  3R05 A;  5JB9 E;  3OLT A;  1YO8 A;  1CEJ A;  2UWP B;  2RA0 L;  3CEN L;  4Y79 B;  1F7M A;  4JYU L;  1CCV A;  4OTJ A;  2I9A A;  1IP0 A;  1U67 A;  3OLU A;  2BMG A;  2PR3 B;  4D90 A;  2J4I B;  5COX A;  3SOB B;  4O1Z A;  3U73 A;  3NTG A;  3H5C B;  4RRW A;  1FE2 A;  1IVO C;  5EGM B;  2DDU A;  3SOV A;  1G2M B;  1IQH L;  1L5G B;  1DX5 I;  1XFE A;  2PHB B;  1DQB A;  2BZ6 L;  2CJI B;  1NPE B;  4CSY A;  1W7X L;  3KRK A;  1EAI C;  2VWM K;  3N8Y A;  4A7I A;  2WPM E;  3LN0 A;  3N8Z A;  1TLE A;  3FFG L;  4BDX A;  1HAF A;  2XBW L;  2JKH L;  3KCG L;  4CUF A;  3N8W A;  3TBD A;  1N7D A;  3KL6 B;  1G1S A;  3NT1 A;  2P26 A;  1EBV A;  3ZYG A;  5F19 A;  1HRE A;  4CUE A;  4NA9 L;  1EQH A;  2Y5G L;  2P28 B;  2Y5F L;  2XBV L;  4PH9 A;  2W26 B;  5F1A A;  1Q4G A;  2VWL L;  1XDT R;  3HS6 A;  4ZHA B;  2Q1J B;  3GIS X;  5L30 L;  3NJP C;  4ZAE B;  5I46 L;  1AUT L;  1SZB A;  2KL7 A;  4Y6D B;  1XKB A;  1WHF A;  4O02 B;  3KK6 A;  1NFX B;  1IQE L;  1XKA L;  1FFM A;  2BOK L;  1MQ5 L;  1IJQ A;  1ATE A;  2J34 B;  1PXX A;  4CUD A;  5KN5 C;  2MHP A;  4Y7B B;  4ZXX L;  1ATD A;  1NFU B;  2W3K B;  1FAX L;  4D0E A;  4YZU B;  4G1M B;  2Y5H L;  5CKQ A;  1TOZ A;  3LC3 B;  2K2T A;  3N8X A;  1NQL B;  4X8U L;  1EMO A;  2FLG A;  4XBM A;  1C5M F;  1P0S L;  1HZ8 A;  1U8C B;  5CKN A;  2BQ6 A;  1EPG A;  3ZYJ B;  1X7A L;  4RRZ A;  3C9A C;  4XL1 A;  1TPG A;  1DDX A;  1LQD A;  3QMO A;  1HX2 A;  2GD4 A;  2J94 B;  5L2Z L;  1IGX A;  1JV2 B;  1EPI A;  1NFY B;  1COU A;  1EPH A;  4BTU A;  2P3F L;  1EMN A;  1K36 A;  1DVA L;  3LC5 B;  1ATB A;  5IKT A;  1JBU L;  4AQT A;  1L3Y A;  3N8V A;  1IQF L;  1HRF A;  2WFT A;  3KQB L;  5E8D A;  1HT8 A;  2K2S B;  2W2P E;  5IKV A;  2BOU A;  2RHP A;  2P3U A;  3CFW A;  2YGP A;  2AYL A;  1KLO A;  1IQJ L;  1CVW L;  2P94 L;  3TGF A;  1I0U A;  2KB9 A;  1YUG A;  6COX A;  2PUQ L;  2EI7 B;  1O5D L;  3IIT B;  1NT0 A;  1G1Q A;  4RUT A;  2ADX A;  3RR3 A;  1APO A;  1YUF A;  1JL9 A;  1LPK A;  2Y80 B;  1OB1 C;  3N8W B;  4ISH L;  2XC5 L;  2VVV L;  2W2O E;  3BPS E;  2MGP A;  1EZQ B;  3V65 B;  2VVU L;  2J38 B;  1HCG B;  2FLB L;  2W2M E;  2XC4 L;  2VWN L;  2Y7Z B;  5JVZ A;  2WPJ E;  1ATA A;  1IQN L;  3BT1 A;  1IOX A;  1BF9 A;  3LTG D;  4YT7 L;  1LMJ A;  1YGC L;  1QFK L;  2EI8 B;  1FAK L;  1ZAQ A;  4OTY A;  2W3I B;  2WYG B;  3HPT A;  4BTT A;  1M1X B;  3K9X A;  4M11 A;  1F0S B;  4C16 A;  4JZD L;  1B9W A;  3ASI A;  2I9B A;  2VJ3 A;  2VH0 B;  3HO4 A;  4ZXY L;  3NTB A;  2OYE P;  4X8V L;  1PRH A;  4RRY A;  4MMX B;  1WHE A;  2P3T A;  3FCS B;  3TK6 B;  1LPG A;  2BO2 A;  3MDL A;  1UZK A;  3TZI A;  1CCF A;  2Y82 B;  5JW1 A;  3FBY A;  2J2U B;  3GCW E;  3TK5 B;  1RFN B;  2W2Q E;  3SOQ A;  1APQ A;  3DEM A;  1PTH A;  3QH0 A;  2WPL E;  1ADX A;  2WPI E;  4Z0K B;  3QCW A;  4ISI L;  2M74 A;  5JBC E;  1IQG L;  2RNL A;  2KV4 A;  1EGF A;  2H9E L;  4LOR A;  4Z0L A;  5JB8 E;  4MMZ B;  1URK A;  1F0R B;  1HT5 A;  3LIW B;  5IKQ A;  4E1G A;  4X8S L;  3U7U G;  1PGE A;  2WG3 C;  3M36 L;  3ENS A;  2VH6 B;  4FM5 A;  1P9J A;  2NPR A;  3CS7 L;  2BOH A;  2W2N E;  3GCX E;  1FJS L;  1IQL L;  1IGZ A;  3EGF A;  1MOX C;  4JYV L;  4TGF A;  5JBB E;  4JZE L;  2WFX B;  2P95 L;  2VVC K;  2BOX A;  3F6U L;  4BTI A;  3LN1 A;  1G2L B;  1FF7 A;  4JZF L;  3Q7D A;  4X8T L;  3MQE A;  4RRX A;  1UZQ A;  4Y71 B;  3N8Y B;  1G1T A;  2J95 B;  1GK5 A;  3LAQ A;  1CX2 A;  1WU1 B;  3KQD L;  5K0H B;  1G1R A;  1KLI L;  2WPH E;  1Z6C A;  2FD6 A;  3HO3 A;  1Z6E L;  1LPZ A;  3POY A;  2P93 L;  4Y76 B;  2F9B L;  2XC0 L;  3TH3 L;  1IQM L;  2TGF A;  2B7D L;  4COX A;  1A3P A;  1NZI A;  4RS0 A;  4NGA L;  2BQ7 A;  1NFW B;  5CIS A;  1DIY A;  3CA7 A;  4M10 A;  1UZJ A;  2Y7X B;  2BQW A;  2UWO B;  2WG4 B;  3PGH A;  5FDQ A;  3HO5 A;  4XLW A;  4MMY B;  4Z6A L;  1PFX L;  3KQC L;  2EI6 B;  3LTF B;  4BXS A;  2D1J B;  1CVU A;  2G00 L;  2OYU P;  1MQ6 L;  1EPJ A;  5IKR A;  1W8B L; 
#chains in the Genus database with same CATH topology
 1EQG A;  2VWO L;  1N1I A;  4LMF A;  1KSN B;  1F7E A;  2WPK E;  1IQK L;  3ELA L;  4Y7A B;  4BDW A;  2YGO A;  1V1I A;  2P16 L;  2Y38 A;  4BXW A;  2FLR L;  4GU3 A;  3SW2 A;  2WYJ B;  1KLJ L;  3HS5 A;  1YUK B;  5L2Y L;  1KKE A;  3KQE L;  1HJ7 A;  5KIR A;  1KIG L;  3BT2 A;  1V3X B;  3IJE B;  3V64 C;  2Y81 B;  2YGQ A;  1J9C L;  2MGR A;  2FZZ L;  4ZH8 B;  4D0F A;  3M37 L;  2XBY L;  3ZYI B;  2BT8 A;  3F1S B;  1UZP A;  3P5B L;  4NG9 L;  1FSB A;  5CKM A;  1IQI L;  2W86 A;  4YT6 L;  5JBA E;  3HS7 A;  1LK9 A;  2UWL B;  2XBX L;  2P3F N;  1CQE A;  1HAE A;  3Q3K B;  1K37 A;  5JVY A;  1IOE L;  3R05 A;  5JB9 E;  3OLT A;  1YO8 A;  1CEJ A;  2UWP B;  2RA0 L;  3CEN L;  4Y79 B;  1F7M A;  4JYU L;  1CCV A;  4OTJ A;  2I9A A;  2JJL A;  1IP0 A;  1U67 A;  3OLU A;  2BMG A;  2PR3 B;  4D90 A;  2J4I B;  5COX A;  3SOB B;  4O1Z A;  3U73 A;  3NTG A;  3H5C B;  4RRW A;  1FE2 A;  1IVO C;  5EGM B;  2DDU A;  3SOV A;  1G2M B;  1IQH L;  1L5G B;  1DX5 I;  1XFE A;  2PHB B;  1DQB A;  2BZ6 L;  2CJI B;  1NPE B;  4CSY A;  1W7X L;  3KRK A;  1EAI C;  2VWM K;  3N8Y A;  4A7I A;  2WPM E;  3LN0 A;  3N8Z A;  1TLE A;  3FFG L;  4BDX A;  1HAF A;  2XBW L;  2JKH L;  3KCG L;  4CUF A;  3N8W A;  3TBD A;  1N7D A;  3KL6 B;  1G1S A;  3NT1 A;  2P26 A;  2BT7 A;  1EBV A;  3ZYG A;  5F19 A;  1HRE A;  4CUE A;  4NA9 L;  1EQH A;  2Y5G L;  2P28 B;  2Y5F L;  2XBV L;  4PH9 A;  2W26 B;  5F1A A;  1Q4G A;  2VWL L;  1XDT R;  3HS6 A;  4ZHA B;  2Q1J B;  3GIS X;  5L30 L;  3NJP C;  4ZAE B;  5I46 L;  1AUT L;  1SZB A;  2KL7 A;  4Y6D B;  1XKB A;  1WHF A;  4O02 B;  3KK6 A;  1NFX B;  1IQE L;  1XKA L;  1FFM A;  2BOK L;  1MQ5 L;  1IJQ A;  1ATE A;  2J34 B;  1PXX A;  4CUD A;  5KN5 C;  1LMM A;  2MHP A;  4Y7B B;  4ZXX L;  1ATD A;  1NFU B;  2W3K B;  1FAX L;  4D0E A;  4YZU B;  4G1M B;  2Y5H L;  5CKQ A;  1TOZ A;  3LC3 B;  2K2T A;  3N8X A;  1NQL B;  4X8U L;  1EMO A;  2FLG A;  4XBM A;  1C5M F;  1P0S L;  1HZ8 A;  1U8C B;  5CKN A;  2BQ6 A;  1EPG A;  3ZYJ B;  1X7A L;  4RRZ A;  3C9A C;  4XL1 A;  1TPG A;  1DDX A;  1LQD A;  3QMO A;  1HX2 A;  2GD4 A;  2J94 B;  5L2Z L;  1IGX A;  1JV2 B;  1EPI A;  1NFY B;  1COU A;  1EPH A;  4BTU A;  2P3F L;  1EMN A;  2BSF A;  3S6X A;  1K36 A;  1DVA L;  3LC5 B;  1ATB A;  5IKT A;  1JBU L;  4AQT A;  1L3Y A;  3N8V A;  1IQF L;  1HRF A;  2WFT A;  3KQB L;  5E8D A;  1HT8 A;  2K2S B;  2W2P E;  5IKV A;  2BOU A;  2RHP A;  2P3U A;  3CFW A;  2YGP A;  2AYL A;  1KLO A;  1IQJ L;  1CVW L;  2P94 L;  3TGF A;  1I0U A;  2KB9 A;  1YUG A;  6COX A;  2PUQ L;  2EI7 B;  1O5D L;  3IIT B;  1NT0 A;  1G1Q A;  4RUT A;  2ADX A;  3RR3 A;  2VRS A;  1APO A;  1YUF A;  1JL9 A;  1LPK A;  2Y80 B;  1OB1 C;  3N8W B;  4ISH L;  2XC5 L;  2VVV L;  2W2O E;  3BPS E;  2MGP A;  1EZQ B;  3V65 B;  2VVU L;  2J38 B;  1HCG B;  2FLB L;  2W2M E;  2XC4 L;  2VWN L;  2Y7Z B;  5JVZ A;  2WPJ E;  1ATA A;  1IQN L;  3BT1 A;  1IOX A;  1BF9 A;  3LTG D;  4YT7 L;  1LMJ A;  1YGC L;  1QFK L;  2EI8 B;  1FAK L;  1ZAQ A;  4OTY A;  2W3I B;  2WYG B;  3HPT A;  4BTT A;  1M1X B;  3K9X A;  4M11 A;  1F0S B;  4C16 A;  4JZD L;  1B9W A;  3ASI A;  2I9B A;  2VJ3 A;  2VH0 B;  3HO4 A;  4ZXY L;  3NTB A;  2OYE P;  4X8V L;  1PRH A;  4RRY A;  4MMX B;  1WHE A;  2P3T A;  3FCS B;  3TK6 B;  1LPG A;  2BO2 A;  3MDL A;  1UZK A;  3TZI A;  1CCF A;  2Y82 B;  5JW1 A;  3FBY A;  2J2U B;  3GCW E;  3TK5 B;  1RFN B;  2W2Q E;  3SOQ A;  1APQ A;  3DEM A;  1PTH A;  3QH0 A;  2WPL E;  1ADX A;  2WPI E;  4Z0K B;  3QCW A;  4ISI L;  2M74 A;  5JBC E;  1IQG L;  2RNL A;  2KV4 A;  1EGF A;  2H9E L;  4LOR A;  4Z0L A;  5JB8 E;  4MMZ B;  1URK A;  1F0R B;  1HT5 A;  1QIU A;  3LIW B;  2HOX A;  4E1G A;  5IKQ A;  4X8S L;  3U7U G;  1PGE A;  2WG3 C;  3M36 L;  3ENS A;  2VH6 B;  4FM5 A;  1P9J A;  2NPR A;  3CS7 L;  2BOH A;  2W2N E;  3GCX E;  1FJS L;  1IQL L;  1IGZ A;  3EGF A;  1MOX C;  2H9E C;  2HOR A;  4JYV L;  1V1H A;  4TGF A;  5JBB E;  4JZE L;  2WFX B;  2P95 L;  2VVC K;  2BOX A;  3F6U L;  4BTI A;  3LN1 A;  1G2L B;  1FF7 A;  4JZF L;  3Q7D A;  4X8T L;  3MQE A;  4RRX A;  1UZQ A;  4Y71 B;  3N8Y B;  2WZP P;  1G1T A;  2J95 B;  1GK5 A;  4A94 C;  3LAQ A;  1CX2 A;  1WU1 B;  3KQD L;  5K0H B;  1G1R A;  1KLI L;  2WPH E;  1Z6C A;  2FD6 A;  3HO3 A;  1Z6E L;  1LPZ A;  3POY A;  2P93 L;  4Y76 B;  2F9B L;  2XC0 L;  3TH3 L;  1IQM L;  2TGF A;  2B7D L;  4COX A;  1A3P A;  1NZI A;  4RS0 A;  4NGA L;  2BQ7 A;  1NFW B;  5CIS A;  1DIY A;  3CA7 A;  4M10 A;  1UZJ A;  2Y7X B;  2KNI A;  2BQW A;  2UWO B;  2WG4 B;  3PGH A;  5FDQ A;  3HO5 A;  4XLW A;  4MMY B;  4Z6A L;  1PFX L;  3KQC L;  2EI6 B;  3LTF B;  4BXS A;  4GU4 A;  2D1J B;  1CVU A;  2G00 L;  2OYU P;  1MQ6 L;  1EPJ A;  5IKR A;  1W8B L; 
#chains in the Genus database with same CATH homology
 1EQG A;  2VWO L;  1N1I A;  4LMF A;  1KSN B;  1F7E A;  2WPK E;  1IQK L;  3ELA L;  4Y7A B;  4BDW A;  2YGO A;  2P16 L;  2Y38 A;  4BXW A;  2FLR L;  3SW2 A;  2WYJ B;  1KLJ L;  3HS5 A;  1YUK B;  5L2Y L;  1HJ7 A;  3KQE L;  5KIR A;  1KIG L;  3BT2 A;  1V3X B;  3IJE B;  3V64 C;  2Y81 B;  2YGQ A;  1J9C L;  2MGR A;  2FZZ L;  4ZH8 B;  4D0F A;  3M37 L;  2XBY L;  3ZYI B;  3F1S B;  1UZP A;  3P5B L;  4NG9 L;  1FSB A;  5CKM A;  1IQI L;  2W86 A;  4YT6 L;  5JBA E;  3HS7 A;  2UWL B;  2XBX L;  2P3F N;  1CQE A;  1HAE A;  3Q3K B;  1K37 A;  5JVY A;  1IOE L;  3R05 A;  5JB9 E;  3OLT A;  1YO8 A;  1CEJ A;  2UWP B;  2RA0 L;  3CEN L;  4Y79 B;  1F7M A;  4JYU L;  1CCV A;  4OTJ A;  2I9A A;  1IP0 A;  1U67 A;  3OLU A;  2BMG A;  2PR3 B;  4D90 A;  2J4I B;  5COX A;  3SOB B;  4O1Z A;  3U73 A;  3NTG A;  3H5C B;  4RRW A;  1FE2 A;  1IVO C;  5EGM B;  2DDU A;  3SOV A;  1G2M B;  1IQH L;  1L5G B;  1DX5 I;  1XFE A;  2PHB B;  1DQB A;  2BZ6 L;  2CJI B;  1NPE B;  4CSY A;  1W7X L;  3KRK A;  1EAI C;  2VWM K;  3N8Y A;  4A7I A;  2WPM E;  3LN0 A;  3N8Z A;  1TLE A;  3FFG L;  4BDX A;  1HAF A;  2XBW L;  2JKH L;  3KCG L;  4CUF A;  3N8W A;  3TBD A;  1N7D A;  3KL6 B;  1G1S A;  3NT1 A;  2P26 A;  1EBV A;  3ZYG A;  5F19 A;  1HRE A;  4CUE A;  4NA9 L;  1EQH A;  2Y5G L;  2P28 B;  2Y5F L;  2XBV L;  4PH9 A;  2W26 B;  5F1A A;  1Q4G A;  2VWL L;  1XDT R;  3HS6 A;  4ZHA B;  2Q1J B;  3GIS X;  5L30 L;  3NJP C;  4ZAE B;  5I46 L;  1AUT L;  1SZB A;  2KL7 A;  4Y6D B;  1XKB A;  1WHF A;  4O02 B;  3KK6 A;  1NFX B;  1IQE L;  1XKA L;  1FFM A;  2BOK L;  1MQ5 L;  1IJQ A;  1ATE A;  2J34 B;  1PXX A;  4CUD A;  5KN5 C;  1LMM A;  2MHP A;  4Y7B B;  4ZXX L;  1ATD A;  1NFU B;  2W3K B;  1FAX L;  4D0E A;  4YZU B;  4G1M B;  2Y5H L;  5CKQ A;  1TOZ A;  3LC3 B;  2K2T A;  3N8X A;  1NQL B;  4X8U L;  1EMO A;  2FLG A;  4XBM A;  1C5M F;  1P0S L;  1HZ8 A;  1U8C B;  5CKN A;  2BQ6 A;  1EPG A;  3ZYJ B;  1X7A L;  4RRZ A;  3C9A C;  4XL1 A;  1TPG A;  1DDX A;  1LQD A;  3QMO A;  1HX2 A;  2GD4 A;  2J94 B;  5L2Z L;  1IGX A;  1JV2 B;  1EPI A;  1NFY B;  1COU A;  1EPH A;  4BTU A;  2P3F L;  1EMN A;  3S6X A;  1K36 A;  1DVA L;  3LC5 B;  1ATB A;  5IKT A;  1JBU L;  4AQT A;  1L3Y A;  3N8V A;  1IQF L;  1HRF A;  2WFT A;  3KQB L;  5E8D A;  1HT8 A;  2K2S B;  2W2P E;  5IKV A;  2BOU A;  2RHP A;  2P3U A;  3CFW A;  2YGP A;  2AYL A;  1KLO A;  1IQJ L;  1CVW L;  2P94 L;  3TGF A;  1I0U A;  2KB9 A;  1YUG A;  6COX A;  2PUQ L;  2EI7 B;  1O5D L;  3IIT B;  1NT0 A;  1G1Q A;  4RUT A;  2ADX A;  3RR3 A;  1APO A;  1YUF A;  1JL9 A;  1LPK A;  2Y80 B;  1OB1 C;  3N8W B;  4ISH L;  2XC5 L;  2VVV L;  2W2O E;  3BPS E;  2MGP A;  1EZQ B;  3V65 B;  2VVU L;  2J38 B;  1HCG B;  2FLB L;  2W2M E;  2XC4 L;  2VWN L;  2Y7Z B;  5JVZ A;  2WPJ E;  1ATA A;  1IQN L;  3BT1 A;  1IOX A;  1BF9 A;  3LTG D;  4YT7 L;  1LMJ A;  1YGC L;  1QFK L;  2EI8 B;  1FAK L;  1ZAQ A;  4OTY A;  2W3I B;  2WYG B;  3HPT A;  4BTT A;  1M1X B;  3K9X A;  4M11 A;  1F0S B;  4C16 A;  4JZD L;  1B9W A;  3ASI A;  2I9B A;  2VJ3 A;  2VH0 B;  3HO4 A;  4ZXY L;  3NTB A;  2OYE P;  4X8V L;  1PRH A;  4RRY A;  4MMX B;  1WHE A;  2P3T A;  3FCS B;  3TK6 B;  1LPG A;  2BO2 A;  3MDL A;  1UZK A;  3TZI A;  1CCF A;  2Y82 B;  5JW1 A;  3FBY A;  2J2U B;  3GCW E;  3TK5 B;  1RFN B;  2W2Q E;  3SOQ A;  1APQ A;  3DEM A;  1PTH A;  3QH0 A;  2WPL E;  1ADX A;  2WPI E;  4Z0K B;  3QCW A;  4ISI L;  2M74 A;  5JBC E;  1IQG L;  2RNL A;  2KV4 A;  1EGF A;  2H9E L;  4LOR A;  4Z0L A;  5JB8 E;  4MMZ B;  1URK A;  1F0R B;  1HT5 A;  3LIW B;  5IKQ A;  4E1G A;  4X8S L;  3U7U G;  1PGE A;  2WG3 C;  3M36 L;  3ENS A;  2VH6 B;  4FM5 A;  1P9J A;  2NPR A;  3CS7 L;  2BOH A;  2W2N E;  3GCX E;  1FJS L;  1IQL L;  1IGZ A;  3EGF A;  1MOX C;  2H9E C;  4JYV L;  4TGF A;  5JBB E;  4JZE L;  2WFX B;  2P95 L;  2VVC K;  2BOX A;  3F6U L;  4BTI A;  3LN1 A;  1G2L B;  1FF7 A;  4JZF L;  3Q7D A;  4X8T L;  3MQE A;  4RRX A;  1UZQ A;  4Y71 B;  3N8Y B;  2WZP P;  1G1T A;  2J95 B;  1GK5 A;  4A94 C;  3LAQ A;  1CX2 A;  1WU1 B;  3KQD L;  5K0H B;  1G1R A;  1KLI L;  2WPH E;  1Z6C A;  2FD6 A;  3HO3 A;  1Z6E L;  1LPZ A;  3POY A;  2P93 L;  4Y76 B;  2F9B L;  2XC0 L;  3TH3 L;  1IQM L;  2TGF A;  2B7D L;  4COX A;  1A3P A;  1NZI A;  4RS0 A;  4NGA L;  2BQ7 A;  1NFW B;  5CIS A;  1DIY A;  3CA7 A;  4M10 A;  1UZJ A;  2Y7X B;  2KNI A;  2BQW A;  2UWO B;  2WG4 B;  3PGH A;  5FDQ A;  3HO5 A;  4XLW A;  4MMY B;  4Z6A L;  1PFX L;  3KQC L;  2EI6 B;  3LTF B;  4BXS A;  2D1J B;  1CVU A;  2G00 L;  2OYU P;  1MQ6 L;  1EPJ A;  5IKR A;  1W8B L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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