1YGCL

Short factor viia with a small molecule inhibitor
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
ICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Coagulation factor VII
total genus 10
structure length 53
sequence length 53
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2005-01-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1ygcL00
3CA7A 2BOUA 3GCXE 2WPKE 1FE2A 4Y6DB 4A7IA 1NFWB 1EPJA 2UWPB 1DIYA 3CS7L 2Y5FL 3HS6A 2J95B 1NFUB 1IQGL 2VVVL 5JBAE 5CKMA 3EGFA 4D90A 4NGAL 4ZXYL 2I9BA 2J2UB 2EI6B 1NPEB 3CENL 1A3PA 5IKQA 1L5GB 3KL6B 1CX2A 3MDLA 1LPKA 1ZAQA 1IQHL 5JB8E 1ATAA 1PRHA 2YGOA 5E8DA 1URKA 2WPIE 3U73A 2PR3B 2PUQL 5IKVA 2WFXB 4LORA 3LN1A 1IQFL 1X7AL 3MQEA 4BXSA 1HAFA 2UWLB 1P0SL 2CJIB 3N8WB 1HJ7A 1MQ6L 4CUEA 1W8BL 1M1XB 4Y76B 2P3FL 5JBBE 6COXA 5JBCE 1IVOC 2FLBL 2Y5GL 3KQEL 2BOXA 2VWLL 1IGXA 2J4IB 1FF7A 1APQA 3CFWA 2W2PE 2Y81B 1PGEA 1EPHA 2XBYL 3SW2A 1QFKL 1G1SA 2MGPA 2I9AA 1F7EA 2FLGA 2VWNL 3GISX 4RRWA 1O5DL 5I46L 1WU1B 2BZ6L 2WPME 1HX2A 1LPZA 3ZYJB 4X8SL 2WPHE 1JBUL 1EMOA 2BOKL 1NQLB 3HO4A 2Q1JB 3QCWA 5EGMB 1UZJA 1DX5I 2WG4B 3ZYIB 1DVAL 1WHFA 3N8ZA 4G1MB 1IQNL 1NT0A 3BPSE 1U67A 1IQLL 3TH3L 3LC5B 5IKRA 4YT6L 1UZKA 1W7XL 1HT5A 1ADXA 2WYJB 1IQML 4M11A 1YUGA 3HPTA 5IKTA 1KLOA 1UZQA 1LPGA 3KCGL 1RFNB 3FBYA 1MQ5L 2JKHL 3QMOA 3RR3A 2XBWL 1G2LB 2XBXL 4ZH8B 2UWOB 4RRZA 4YT7L 1KLJL 1EBVA 2VJ3A 2Y7XB 3HS5A 2KV4A 1C5MF 2BQ6A 3TBDA 4Y71B 4MMZB 1EQGA 4FM5A 1FJSL 1ATEA 2KB9A 4Y7AB 1K37A 2BOHA 3N8YA 2VVUL 5KIRA 1G1RA 1HCGB 4RRYA 3KQDL 2W3KB 3DEMA 2F9BL 3N8XA 4D0FA 4E1GA 1ATDA 3ELAL 2M74A 1CVWL 2VWOL 3M37L 4RS0A 1HAEA 1DQBA 2BQWA 1HRFA 4JZDL 1PTHA 3F6UL 3IITB 3FCSB 2EI7B 5COXA 4CUDA 3NTGA 1KIGL 1IGZA 2GD4A 1F0RB 3N8WA 4BDWA 1XDTR 1HREA 3LTFB 2WPLE 1B9WA 4OTYA 2FLRL 3H5CB 2VH0B 4O1ZA 2D1JB 1FAXL 1OB1C 1Z6CA 1AUTL 3LAQA 3LC3B 2WG3C 3SOBB 2P28B 1HZ8A 1EGFA 4RRXA 4Y79B 5JVYA 1Z6EL 2Y7ZB 2P3UA 3NJPC 1CVUA 3SOQA 1Q4GA 2TGFA 1KSNB 5L2ZL 3V65B 4BDXA 4BXWA 4ZHAB 2W2QE 4C16A 1K36A 1P9JA 2WPJE 2P16L 3OLTA 1BF9A 3Q3KB 1DDXA 1EAIC 2Y38A 4X8VL 5CKQA 1GK5A 2FD6A 2J94B 4ISHL 1WHEA 4X8TL 2XBVL 2YGPA 1IQIL 1JL9A 2J38B 2RHPA 2P94L 1XKAL 4Y7BB 3TZIA 2W3IB 3Q7DA 5L30L 1FSBA 2W2OE 3N8VA 1EPGA 3HO5A 5L2YL 4XLWA 1IP0A 3NTBA 3PGHA 2WFTA 4BTTA 1PXXA 2W86A 2BQ7A 3FFGL 2MGRA 1FFMA 1CQEA 1NFXB 4M10A 2DDUA 2EI8B 4ZAEB 3ENSA 1APOA 4YZUB 4O02B 3K9XA 4BTIA 4XBMA 4NG9L 3KQCL 1LMJA 5FDQA 1G1QA 3QH0A 4LMFA 1N7DA 2G00L 2K2TA 4COXA 2AYLA 2VVCK 3IJEB 3U7UG 1FAKL 5F19A 2NPRA 3BT2A 2Y5HL 2VH6B 2BMGA 2P26A 1TOZA 3V64C 2Y82B 3KRKA 1XKBA 3N8YB 4JZEL 2P95L 2BO2A 1XFEA 3C9AC 1EQHA 2K2SB 1YGCL 5JB9E 1UZPA 2Y80B 4CUFA 2PHBB 2OYUP 4TGFA 3BT1A 3M36L 1YUKB 2ADXA 2KL7A 2J34B 1CCVA 1F0SB 4Z0LA 3OLUA 1IQEL 1J9CL 1G2MB 2VWMK 3ZYGA 1G1TA 3P5BL 4JZFL 4Z6AL 2XC4L 5JVZA 4Z0KB 3NT1A 2P3FN 1IQKL 2FZZL 3ASIA 1TPGA 4BTUA 2W2ME 2H9EL 1I0UA 2WYGB 3R05A 4CSYA 1L3YA 5F1AA 1ATBA 3LIWB 1KLIL 2W26B 4X8UL 4OTJA 2RA0L 1IQJL 3TGFA 1CEJA 2B7DL 2XC0L 1MOXC 3TK6B 1TLEA 2P93L 5JW1A 3KQBL 1LQDA 3POYA 1F7MA 4D0EA 4MMXB 1IJQA 4XL1A 5K0HB 1EPIA 1CCFA 1EZQB 4RUTA 4JYUL 3F1SB 2XC5L 4ZXXL 4AQTA 2MHPA 1IOXA 1YO8A 3GCWE 1JV2B 3HS7A 4ISIL 1V3XB 4MMYB 1YUFA 1IOEL 3LN0A 4JYVL 4PH9A 3HO3A 2RNLA 1N1IA 1PFXL 4NA9L 5KN5C 1NZIA 5CISA 1HT8A 3KK6A 3SOVA 2W2NE 3TK5B 1SZBA 1EMNA 1U8CB 3LTGD 5CKNA 1COUA 2OYEP 2P3TA 1NFYB
chains in the Genus database with same CATH superfamily
3CA7A 2BOUA 3GCXE 2WPKE 1KKEA 1FE2A 4Y6DB 4A7IA 1NFWB 1EPJA 2UWPB 1DIYA 3CS7L 2Y5FL 3HS6A 2J95B 1NFUB 1IQGL 2VVVL 5JBAE 5CKMA 3EGFA 4D90A 4NGAL 4ZXYL 2I9BA 2J2UB 2EI6B 1NPEB 3CENL 1A3PA 5IKQA 1L5GB 3KL6B 1CX2A 3MDLA 1LPKA 1ZAQA 1IQHL 1LMMA 5JB8E 1ATAA 1PRHA 2YGOA 5E8DA 1URKA 2WPIE 3U73A 4GU4A 2PR3B 2PUQL 5IKVA 2WFXB 4LORA 3LN1A 1IQFL 1X7AL 3MQEA 4BXSA 1HAFA 2UWLB 1P0SL 2CJIB 3N8WB 1HJ7A 1MQ6L 4CUEA 1W8BL 1M1XB 4Y76B 2P3FL 5JBBE 6COXA 5JBCE 1IVOC 2FLBL 2Y5GL 3KQEL 3S6XA 2BOXA 2VWLL 1IGXA 2J4IB 1FF7A 1APQA 2YGQA 3CFWA 2W2PE 2Y81B 1PGEA 1EPHA 2XBYL 3SW2A 1QFKL 1G1SA 2MGPA 2I9AA 1F7EA 2FLGA 2VWNL 3GISX 4RRWA 1V1HA 1O5DL 5I46L 1WU1B 2BZ6L 2WPME 1HX2A 1LPZA 3ZYJB 4X8SL 2WPHE 1JBUL 1EMOA 2BOKL 1NQLB 3HO4A 2Q1JB 3QCWA 5EGMB 1UZJA 1DX5I 2WG4B 3ZYIB 1DVAL 1WHFA 3N8ZA 4G1MB 1IQNL 1NT0A 3BPSE 1U67A 1IQLL 3TH3L 3LC5B 5IKRA 4YT6L 1UZKA 1W7XL 1HT5A 1ADXA 2WYJB 1IQML 4M11A 1YUGA 3HPTA 5IKTA 1KLOA 1UZQA 1LPGA 3KCGL 1RFNB 3FBYA 1MQ5L 2H9EC 2JKHL 3QMOA 3RR3A 2XBWL 1G2LB 2XBXL 4ZH8B 2UWOB 4RRZA 4YT7L 1KLJL 1EBVA 2VJ3A 2Y7XB 3HS5A 2KV4A 1C5MF 2BQ6A 3TBDA 1LK9A 4Y71B 4MMZB 1EQGA 4FM5A 1FJSL 1ATEA 2KB9A 4Y7AB 1K37A 2BOHA 3N8YA 2VVUL 5KIRA 1G1RA 1HCGB 4RRYA 2HOXA 2VRSA 3KQDL 2W3KB 3DEMA 2F9BL 3N8XA 4D0FA 4E1GA 1ATDA 3ELAL 2M74A 1CVWL 2VWOL 3M37L 4RS0A 1HAEA 1DQBA 2BQWA 1HRFA 4JZDL 1PTHA 3F6UL 3IITB 3FCSB 2EI7B 5COXA 4CUDA 3NTGA 1KIGL 1IGZA 2GD4A 1F0RB 3N8WA 4BDWA 1XDTR 1HREA 3LTFB 2WPLE 1B9WA 4OTYA 2FLRL 3H5CB 2VH0B 4O1ZA 2D1JB 2HORA 1FAXL 1OB1C 1Z6CA 1AUTL 3LAQA 3LC3B 2WG3C 3SOBB 2P28B 1HZ8A 1EGFA 4RRXA 4Y79B 5JVYA 1Z6EL 2Y7ZB 2P3UA 3NJPC 1CVUA 3SOQA 1Q4GA 2TGFA 1KSNB 5L2ZL 3V65B 4BDXA 4BXWA 4ZHAB 2W2QE 4C16A 1K36A 1P9JA 2WPJE 2P16L 3OLTA 1BF9A 3Q3KB 1DDXA 1EAIC 2Y38A 2BT8A 4X8VL 5CKQA 1GK5A 2FD6A 2J94B 4ISHL 1WHEA 4X8TL 2XBVL 2YGPA 1IQIL 1JL9A 2J38B 2RHPA 2P94L 1XKAL 4Y7BB 3TZIA 2W3IB 3Q7DA 5L30L 1FSBA 2W2OE 3N8VA 1EPGA 3HO5A 5L2YL 4XLWA 1IP0A 3NTBA 3PGHA 2WFTA 4BTTA 1PXXA 2W86A 2BQ7A 3FFGL 2MGRA 1FFMA 1CQEA 1NFXB 4M10A 2DDUA 2EI8B 4ZAEB 3ENSA 1APOA 4YZUB 4O02B 3K9XA 4BTIA 4XBMA 4NG9L 3KQCL 1LMJA 5FDQA 1G1QA 3QH0A 4LMFA 1N7DA 2G00L 2K2TA 4COXA 2AYLA 2VVCK 3IJEB 3U7UG 1FAKL 5F19A 2NPRA 3BT2A 2Y5HL 2VH6B 2BMGA 2P26A 1TOZA 3V64C 2Y82B 3KRKA 1XKBA 3N8YB 4JZEL 2P95L 2BO2A 1XFEA 3C9AC 1EQHA 2K2SB 1YGCL 5JB9E 1UZPA 2Y80B 4CUFA 2PHBB 2OYUP 4TGFA 3BT1A 3M36L 1YUKB 2ADXA 2KL7A 2J34B 1CCVA 1F0SB 4Z0LA 3OLUA 1IQEL 2JJLA 1J9CL 1G2MB 2VWMK 3ZYGA 1G1TA 3P5BL 4JZFL 4Z6AL 2XC4L 5JVZA 4Z0KB 3NT1A 2P3FN 1IQKL 2FZZL 3ASIA 4GU3A 1TPGA 4BTUA 2W2ME 2H9EL 1I0UA 2WYGB 3R05A 4CSYA 1V1IA 1L3YA 5F1AA 1ATBA 3LIWB 1KLIL 2W26B 4X8UL 4OTJA 2KNIA 2RA0L 1IQJL 3TGFA 1CEJA 4A94C 2B7DL 2XC0L 1MOXC 3TK6B 1TLEA 2P93L 5JW1A 3KQBL 1LQDA 3POYA 1F7MA 4D0EA 4MMXB 1IJQA 4XL1A 5K0HB 1EPIA 1CCFA 1EZQB 4RUTA 4JYUL 2BSFA 3F1SB 2XC5L 1QIUA 4ZXXL 4AQTA 2MHPA 1IOXA 1YO8A 3GCWE 1JV2B 3HS7A 4ISIL 1V3XB 4MMYB 1YUFA 1IOEL 3LN0A 4JYVL 4PH9A 3HO3A 2RNLA 1N1IA 1PFXL 4NA9L 5KN5C 1NZIA 5CISA 1HT8A 3KK6A 3SOVA 2W2NE 3TK5B 2WZPP 1SZBA 2BT7A 1EMNA 1U8CB 3LTGD 5CKNA 1COUA 2OYEP 2P3TA 1NFYB
chains in the Genus database with same CATH topology
3CA7A 2BOUA 3GCXE 2WPKE 1FE2A 4Y6DB 4A7IA 1NFWB 1EPJA 2UWPB 1DIYA 3CS7L 2Y5FL 3HS6A 2J95B 1NFUB 1IQGL 2VVVL 5JBAE 5CKMA 3EGFA 4D90A 4NGAL 4ZXYL 2I9BA 2J2UB 2EI6B 1NPEB 3CENL 1A3PA 5IKQA 1L5GB 3KL6B 1CX2A 3MDLA 1LPKA 1ZAQA 1IQHL 1LMMA 5JB8E 1ATAA 1PRHA 2YGOA 5E8DA 1URKA 2WPIE 3U73A 2PR3B 2PUQL 5IKVA 2WFXB 4LORA 3LN1A 1IQFL 1X7AL 3MQEA 4BXSA 1HAFA 2UWLB 1P0SL 2CJIB 3N8WB 1HJ7A 1MQ6L 4CUEA 1W8BL 1M1XB 4Y76B 2P3FL 5JBBE 6COXA 5JBCE 1IVOC 2FLBL 2Y5GL 3KQEL 3S6XA 2BOXA 2VWLL 1IGXA 2J4IB 1FF7A 1APQA 2YGQA 3CFWA 2W2PE 2Y81B 1PGEA 1EPHA 2XBYL 3SW2A 1QFKL 1G1SA 2MGPA 2I9AA 1F7EA 2FLGA 2VWNL 3GISX 4RRWA 1O5DL 5I46L 1WU1B 2BZ6L 2WPME 1HX2A 1LPZA 3ZYJB 4X8SL 2WPHE 1JBUL 1EMOA 2BOKL 1NQLB 3HO4A 2Q1JB 3QCWA 5EGMB 1UZJA 1DX5I 2WG4B 3ZYIB 1DVAL 1WHFA 3N8ZA 4G1MB 1IQNL 1NT0A 3BPSE 1U67A 1IQLL 3TH3L 3LC5B 5IKRA 4YT6L 1UZKA 1W7XL 1HT5A 1ADXA 2WYJB 1IQML 4M11A 1YUGA 3HPTA 5IKTA 1KLOA 1UZQA 1LPGA 3KCGL 1RFNB 3FBYA 1MQ5L 2H9EC 2JKHL 3QMOA 3RR3A 2XBWL 1G2LB 2XBXL 4ZH8B 2UWOB 4RRZA 4YT7L 1KLJL 1EBVA 2VJ3A 2Y7XB 3HS5A 2KV4A 1C5MF 2BQ6A 3TBDA 4Y71B 4MMZB 1EQGA 4FM5A 1FJSL 1ATEA 2KB9A 4Y7AB 1K37A 2BOHA 3N8YA 2VVUL 5KIRA 1G1RA 1HCGB 4RRYA 3KQDL 2W3KB 3DEMA 2F9BL 3N8XA 4D0FA 4E1GA 1ATDA 3ELAL 2M74A 1CVWL 3M37L 2VWOL 4RS0A 1HAEA 1DQBA 2BQWA 1HRFA 4JZDL 1PTHA 3F6UL 3IITB 3FCSB 2EI7B 5COXA 4CUDA 3NTGA 1KIGL 1IGZA 2GD4A 1F0RB 3N8WA 4BDWA 1XDTR 1HREA 3LTFB 2WPLE 1B9WA 4OTYA 2FLRL 3H5CB 2VH0B 4O1ZA 2D1JB 1FAXL 1OB1C 1Z6CA 1AUTL 3LAQA 3LC3B 2WG3C 3SOBB 2P28B 1HZ8A 1EGFA 4RRXA 4Y79B 5JVYA 1Z6EL 2Y7ZB 2P3UA 3NJPC 1CVUA 3SOQA 1Q4GA 2TGFA 1KSNB 5L2ZL 3V65B 4BDXA 4BXWA 4ZHAB 2W2QE 4C16A 1K36A 1P9JA 2WPJE 2P16L 3OLTA 1BF9A 3Q3KB 1DDXA 1EAIC 2Y38A 4X8VL 5CKQA 1GK5A 2FD6A 2J94B 4ISHL 1WHEA 4X8TL 2XBVL 2YGPA 1IQIL 1JL9A 2J38B 2RHPA 2P94L 1XKAL 4Y7BB 3TZIA 2W3IB 3Q7DA 5L30L 1FSBA 2W2OE 3N8VA 1EPGA 3HO5A 5L2YL 4XLWA 1IP0A 3NTBA 3PGHA 2WFTA 4BTTA 1PXXA 2W86A 2BQ7A 3FFGL 2MGRA 1FFMA 1CQEA 1NFXB 4M10A 2DDUA 2EI8B 4ZAEB 3ENSA 1APOA 4YZUB 4O02B 3K9XA 4BTIA 4XBMA 4NG9L 3KQCL 1LMJA 5FDQA 1G1QA 3QH0A 4LMFA 1N7DA 2G00L 2K2TA 4COXA 2AYLA 2VVCK 3IJEB 3U7UG 1FAKL 5F19A 2NPRA 3BT2A 2Y5HL 2VH6B 2BMGA 2P26A 1TOZA 3V64C 2Y82B 3KRKA 1XKBA 3N8YB 4JZEL 2P95L 2BO2A 1XFEA 3C9AC 1EQHA 2K2SB 1YGCL 5JB9E 1UZPA 2Y80B 4CUFA 2PHBB 2OYUP 4TGFA 3BT1A 3M36L 1YUKB 2ADXA 2KL7A 2J34B 1CCVA 1F0SB 4Z0LA 3OLUA 1IQEL 1J9CL 1G2MB 2VWMK 3ZYGA 1G1TA 3P5BL 4JZFL 4Z6AL 2XC4L 5JVZA 4Z0KB 3NT1A 2P3FN 1IQKL 2FZZL 3ASIA 1TPGA 4BTUA 2W2ME 2H9EL 1I0UA 2WYGB 3R05A 4CSYA 1L3YA 5F1AA 1ATBA 3LIWB 1KLIL 2W26B 4X8UL 4OTJA 2KNIA 2RA0L 1IQJL 3TGFA 1CEJA 4A94C 2B7DL 2XC0L 1MOXC 3TK6B 1TLEA 2P93L 5JW1A 3KQBL 1LQDA 3POYA 1F7MA 4D0EA 4MMXB 1IJQA 4XL1A 5K0HB 1EPIA 1CCFA 1EZQB 4RUTA 4JYUL 3F1SB 2XC5L 4ZXXL 4AQTA 2MHPA 1IOXA 1YO8A 3GCWE 1JV2B 3HS7A 4ISIL 1V3XB 4MMYB 1YUFA 1IOEL 3LN0A 4JYVL 4PH9A 3HO3A 2RNLA 1N1IA 1PFXL 4NA9L 5KN5C 1NZIA 5CISA 1HT8A 3KK6A 3SOVA 2W2NE 3TK5B 2WZPP 1SZBA 1EMNA 1U8CB 3LTGD 5CKNA 1COUA 2OYEP 2P3TA 1NFYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CA7 A;  2BOU A;  3GCX E;  2WPK E;  1FE2 A;  4Y6D B;  4A7I A;  1NFW B;  1EPJ A;  2UWP B;  1DIY A;  3CS7 L;  2Y5F L;  3HS6 A;  2J95 B;  1NFU B;  1IQG L;  2VVV L;  5JBA E;  5CKM A;  3EGF A;  4D90 A;  4NGA L;  4ZXY L;  2I9B A;  2J2U B;  2EI6 B;  1NPE B;  3CEN L;  1A3P A;  5IKQ A;  1L5G B;  3KL6 B;  1CX2 A;  3MDL A;  1LPK A;  1ZAQ A;  1IQH L;  5JB8 E;  1ATA A;  1PRH A;  2YGO A;  5E8D A;  1URK A;  2WPI E;  3U73 A;  2PR3 B;  2PUQ L;  5IKV A;  2WFX B;  4LOR A;  3LN1 A;  1IQF L;  1X7A L;  3MQE A;  4BXS A;  1HAF A;  2UWL B;  1P0S L;  2CJI B;  3N8W B;  1HJ7 A;  1MQ6 L;  4CUE A;  1W8B L;  1M1X B;  4Y76 B;  2P3F L;  5JBB E;  6COX A;  5JBC E;  1IVO C;  2FLB L;  2Y5G L;  3KQE L;  2BOX A;  2VWL L;  1IGX A;  2J4I B;  1FF7 A;  1APQ A;  3CFW A;  2W2P E;  2Y81 B;  1PGE A;  1EPH A;  2XBY L;  3SW2 A;  1QFK L;  1G1S A;  2MGP A;  2I9A A;  1F7E A;  2FLG A;  2VWN L;  3GIS X;  4RRW A;  1O5D L;  5I46 L;  1WU1 B;  2BZ6 L;  2WPM E;  1HX2 A;  1LPZ A;  3ZYJ B;  4X8S L;  2WPH E;  1JBU L;  1EMO A;  2BOK L;  1NQL B;  3HO4 A;  2Q1J B;  3QCW A;  5EGM B;  1UZJ A;  1DX5 I;  2WG4 B;  3ZYI B;  1DVA L;  1WHF A;  3N8Z A;  4G1M B;  1IQN L;  1NT0 A;  3BPS E;  1U67 A;  1IQL L;  3TH3 L;  3LC5 B;  5IKR A;  4YT6 L;  1UZK A;  1W7X L;  1HT5 A;  1ADX A;  2WYJ B;  1IQM L;  4M11 A;  1YUG A;  3HPT A;  5IKT A;  1KLO A;  1UZQ A;  1LPG A;  3KCG L;  1RFN B;  3FBY A;  1MQ5 L;  2JKH L;  3QMO A;  3RR3 A;  2XBW L;  1G2L B;  2XBX L;  4ZH8 B;  2UWO B;  4RRZ A;  4YT7 L;  1KLJ L;  1EBV A;  2VJ3 A;  2Y7X B;  3HS5 A;  2KV4 A;  1C5M F;  2BQ6 A;  3TBD A;  4Y71 B;  4MMZ B;  1EQG A;  4FM5 A;  1FJS L;  1ATE A;  2KB9 A;  4Y7A B;  1K37 A;  2BOH A;  3N8Y A;  2VVU L;  5KIR A;  1G1R A;  1HCG B;  4RRY A;  3KQD L;  2W3K B;  3DEM A;  2F9B L;  3N8X A;  4D0F A;  4E1G A;  1ATD A;  3ELA L;  2M74 A;  1CVW L;  2VWO L;  3M37 L;  4RS0 A;  1HAE A;  1DQB A;  2BQW A;  1HRF A;  4JZD L;  1PTH A;  3F6U L;  3IIT B;  3FCS B;  2EI7 B;  5COX A;  4CUD A;  3NTG A;  1KIG L;  1IGZ A;  2GD4 A;  1F0R B;  3N8W A;  4BDW A;  1XDT R;  1HRE A;  3LTF B;  2WPL E;  1B9W A;  4OTY A;  2FLR L;  3H5C B;  2VH0 B;  4O1Z A;  2D1J B;  1FAX L;  1OB1 C;  1Z6C A;  1AUT L;  3LAQ A;  3LC3 B;  2WG3 C;  3SOB B;  2P28 B;  1HZ8 A;  1EGF A;  4RRX A;  4Y79 B;  5JVY A;  1Z6E L;  2Y7Z B;  2P3U A;  3NJP C;  1CVU A;  3SOQ A;  1Q4G A;  2TGF A;  1KSN B;  5L2Z L;  3V65 B;  4BDX A;  4BXW A;  4ZHA B;  2W2Q E;  4C16 A;  1K36 A;  1P9J A;  2WPJ E;  2P16 L;  3OLT A;  1BF9 A;  3Q3K B;  1DDX A;  1EAI C;  2Y38 A;  4X8V L;  5CKQ A;  1GK5 A;  2FD6 A;  2J94 B;  4ISH L;  1WHE A;  4X8T L;  2XBV L;  2YGP A;  1IQI L;  1JL9 A;  2J38 B;  2RHP A;  2P94 L;  1XKA L;  4Y7B B;  3TZI A;  2W3I B;  3Q7D A;  5L30 L;  1FSB A;  2W2O E;  3N8V A;  1EPG A;  3HO5 A;  5L2Y L;  4XLW A;  1IP0 A;  3NTB A;  3PGH A;  2WFT A;  4BTT A;  1PXX A;  2W86 A;  2BQ7 A;  3FFG L;  2MGR A;  1FFM A;  1CQE A;  1NFX B;  4M10 A;  2DDU A;  2EI8 B;  4ZAE B;  3ENS A;  1APO A;  4YZU B;  4O02 B;  3K9X A;  4BTI A;  4XBM A;  4NG9 L;  3KQC L;  1LMJ A;  5FDQ A;  1G1Q A;  3QH0 A;  4LMF A;  1N7D A;  2G00 L;  2K2T A;  4COX A;  2AYL A;  2VVC K;  3IJE B;  3U7U G;  1FAK L;  5F19 A;  2NPR A;  3BT2 A;  2Y5H L;  2VH6 B;  2BMG A;  2P26 A;  1TOZ A;  3V64 C;  2Y82 B;  3KRK A;  1XKB A;  3N8Y B;  4JZE L;  2P95 L;  2BO2 A;  1XFE A;  3C9A C;  1EQH A;  2K2S B;  1YGC L;  5JB9 E;  1UZP A;  2Y80 B;  4CUF A;  2PHB B;  2OYU P;  4TGF A;  3BT1 A;  3M36 L;  1YUK B;  2ADX A;  2KL7 A;  2J34 B;  1CCV A;  1F0S B;  4Z0L A;  3OLU A;  1IQE L;  1J9C L;  1G2M B;  2VWM K;  3ZYG A;  1G1T A;  3P5B L;  4JZF L;  4Z6A L;  2XC4 L;  5JVZ A;  4Z0K B;  3NT1 A;  2P3F N;  1IQK L;  2FZZ L;  3ASI A;  1TPG A;  4BTU A;  2W2M E;  2H9E L;  1I0U A;  2WYG B;  3R05 A;  4CSY A;  1L3Y A;  5F1A A;  1ATB A;  3LIW B;  1KLI L;  2W26 B;  4X8U L;  4OTJ A;  2RA0 L;  1IQJ L;  3TGF A;  1CEJ A;  2B7D L;  2XC0 L;  1MOX C;  3TK6 B;  1TLE A;  2P93 L;  5JW1 A;  3KQB L;  1LQD A;  3POY A;  1F7M A;  4D0E A;  4MMX B;  1IJQ A;  4XL1 A;  5K0H B;  1EPI A;  1CCF A;  1EZQ B;  4RUT A;  4JYU L;  3F1S B;  2XC5 L;  4ZXX L;  4AQT A;  2MHP A;  1IOX A;  1YO8 A;  3GCW E;  1JV2 B;  3HS7 A;  4ISI L;  1V3X B;  4MMY B;  1YUF A;  1IOE L;  3LN0 A;  4JYV L;  4PH9 A;  3HO3 A;  2RNL A;  1N1I A;  1PFX L;  4NA9 L;  5KN5 C;  1NZI A;  5CIS A;  1HT8 A;  3KK6 A;  3SOV A;  2W2N E;  3TK5 B;  1SZB A;  1EMN A;  1U8C B;  3LTG D;  5CKN A;  1COU A;  2OYE P;  2P3T A;  1NFY B; 
#chains in the Genus database with same CATH topology
 3CA7 A;  2BOU A;  3GCX E;  2WPK E;  1KKE A;  1FE2 A;  4Y6D B;  4A7I A;  1NFW B;  1EPJ A;  2UWP B;  1DIY A;  3CS7 L;  2Y5F L;  3HS6 A;  2J95 B;  1NFU B;  1IQG L;  2VVV L;  5JBA E;  5CKM A;  3EGF A;  4D90 A;  4NGA L;  4ZXY L;  2I9B A;  2J2U B;  2EI6 B;  1NPE B;  3CEN L;  1A3P A;  5IKQ A;  1L5G B;  3KL6 B;  1CX2 A;  3MDL A;  1LPK A;  1ZAQ A;  1IQH L;  1LMM A;  5JB8 E;  1ATA A;  1PRH A;  2YGO A;  5E8D A;  1URK A;  2WPI E;  3U73 A;  4GU4 A;  2PR3 B;  2PUQ L;  5IKV A;  2WFX B;  4LOR A;  3LN1 A;  1IQF L;  1X7A L;  3MQE A;  4BXS A;  1HAF A;  2UWL B;  1P0S L;  2CJI B;  3N8W B;  1HJ7 A;  1MQ6 L;  4CUE A;  1W8B L;  1M1X B;  4Y76 B;  2P3F L;  5JBB E;  6COX A;  5JBC E;  1IVO C;  2FLB L;  2Y5G L;  3KQE L;  3S6X A;  2BOX A;  2VWL L;  1IGX A;  2J4I B;  1FF7 A;  1APQ A;  2YGQ A;  3CFW A;  2W2P E;  2Y81 B;  1PGE A;  1EPH A;  2XBY L;  3SW2 A;  1QFK L;  1G1S A;  2MGP A;  2I9A A;  1F7E A;  2FLG A;  2VWN L;  3GIS X;  4RRW A;  1V1H A;  1O5D L;  5I46 L;  1WU1 B;  2BZ6 L;  2WPM E;  1HX2 A;  1LPZ A;  3ZYJ B;  4X8S L;  2WPH E;  1JBU L;  1EMO A;  2BOK L;  1NQL B;  3HO4 A;  2Q1J B;  3QCW A;  5EGM B;  1UZJ A;  1DX5 I;  2WG4 B;  3ZYI B;  1DVA L;  1WHF A;  3N8Z A;  4G1M B;  1IQN L;  1NT0 A;  3BPS E;  1U67 A;  1IQL L;  3TH3 L;  3LC5 B;  5IKR A;  4YT6 L;  1UZK A;  1W7X L;  1HT5 A;  1ADX A;  2WYJ B;  1IQM L;  4M11 A;  1YUG A;  3HPT A;  5IKT A;  1KLO A;  1UZQ A;  1LPG A;  3KCG L;  1RFN B;  3FBY A;  1MQ5 L;  2H9E C;  2JKH L;  3QMO A;  3RR3 A;  2XBW L;  1G2L B;  2XBX L;  4ZH8 B;  2UWO B;  4RRZ A;  4YT7 L;  1KLJ L;  1EBV A;  2VJ3 A;  2Y7X B;  3HS5 A;  2KV4 A;  1C5M F;  2BQ6 A;  3TBD A;  1LK9 A;  4Y71 B;  4MMZ B;  1EQG A;  4FM5 A;  1FJS L;  1ATE A;  2KB9 A;  4Y7A B;  1K37 A;  2BOH A;  3N8Y A;  2VVU L;  5KIR A;  1G1R A;  1HCG B;  4RRY A;  2HOX A;  2VRS A;  3KQD L;  2W3K B;  3DEM A;  2F9B L;  3N8X A;  4D0F A;  4E1G A;  1ATD A;  3ELA L;  2M74 A;  1CVW L;  2VWO L;  3M37 L;  4RS0 A;  1HAE A;  1DQB A;  2BQW A;  1HRF A;  4JZD L;  1PTH A;  3F6U L;  3IIT B;  3FCS B;  2EI7 B;  5COX A;  4CUD A;  3NTG A;  1KIG L;  1IGZ A;  2GD4 A;  1F0R B;  3N8W A;  4BDW A;  1XDT R;  1HRE A;  3LTF B;  2WPL E;  1B9W A;  4OTY A;  2FLR L;  3H5C B;  2VH0 B;  4O1Z A;  2D1J B;  2HOR A;  1FAX L;  1OB1 C;  1Z6C A;  1AUT L;  3LAQ A;  3LC3 B;  2WG3 C;  3SOB B;  2P28 B;  1HZ8 A;  1EGF A;  4RRX A;  4Y79 B;  5JVY A;  1Z6E L;  2Y7Z B;  2P3U A;  3NJP C;  1CVU A;  3SOQ A;  1Q4G A;  2TGF A;  1KSN B;  5L2Z L;  3V65 B;  4BDX A;  4BXW A;  4ZHA B;  2W2Q E;  4C16 A;  1K36 A;  1P9J A;  2WPJ E;  2P16 L;  3OLT A;  1BF9 A;  3Q3K B;  1DDX A;  1EAI C;  2Y38 A;  2BT8 A;  4X8V L;  5CKQ A;  1GK5 A;  2FD6 A;  2J94 B;  4ISH L;  1WHE A;  4X8T L;  2XBV L;  2YGP A;  1IQI L;  1JL9 A;  2J38 B;  2RHP A;  2P94 L;  1XKA L;  4Y7B B;  3TZI A;  2W3I B;  3Q7D A;  5L30 L;  1FSB A;  2W2O E;  3N8V A;  1EPG A;  3HO5 A;  5L2Y L;  4XLW A;  1IP0 A;  3NTB A;  3PGH A;  2WFT A;  4BTT A;  1PXX A;  2W86 A;  2BQ7 A;  3FFG L;  2MGR A;  1FFM A;  1CQE A;  1NFX B;  4M10 A;  2DDU A;  2EI8 B;  4ZAE B;  3ENS A;  1APO A;  4YZU B;  4O02 B;  3K9X A;  4BTI A;  4XBM A;  4NG9 L;  3KQC L;  1LMJ A;  5FDQ A;  1G1Q A;  3QH0 A;  4LMF A;  1N7D A;  2G00 L;  2K2T A;  4COX A;  2AYL A;  2VVC K;  3IJE B;  3U7U G;  1FAK L;  5F19 A;  2NPR A;  3BT2 A;  2Y5H L;  2VH6 B;  2BMG A;  2P26 A;  1TOZ A;  3V64 C;  2Y82 B;  3KRK A;  1XKB A;  3N8Y B;  4JZE L;  2P95 L;  2BO2 A;  1XFE A;  3C9A C;  1EQH A;  2K2S B;  1YGC L;  5JB9 E;  1UZP A;  2Y80 B;  4CUF A;  2PHB B;  2OYU P;  4TGF A;  3BT1 A;  3M36 L;  1YUK B;  2ADX A;  2KL7 A;  2J34 B;  1CCV A;  1F0S B;  4Z0L A;  3OLU A;  1IQE L;  2JJL A;  1J9C L;  1G2M B;  2VWM K;  3ZYG A;  1G1T A;  3P5B L;  4JZF L;  4Z6A L;  2XC4 L;  5JVZ A;  4Z0K B;  3NT1 A;  2P3F N;  1IQK L;  2FZZ L;  3ASI A;  4GU3 A;  1TPG A;  4BTU A;  2W2M E;  2H9E L;  1I0U A;  2WYG B;  3R05 A;  4CSY A;  1V1I A;  1L3Y A;  5F1A A;  1ATB A;  3LIW B;  1KLI L;  2W26 B;  4X8U L;  4OTJ A;  2KNI A;  2RA0 L;  1IQJ L;  3TGF A;  1CEJ A;  4A94 C;  2B7D L;  2XC0 L;  1MOX C;  3TK6 B;  1TLE A;  2P93 L;  5JW1 A;  3KQB L;  1LQD A;  3POY A;  1F7M A;  4D0E A;  4MMX B;  1IJQ A;  4XL1 A;  5K0H B;  1EPI A;  1CCF A;  1EZQ B;  4RUT A;  4JYU L;  2BSF A;  3F1S B;  2XC5 L;  1QIU A;  4ZXX L;  4AQT A;  2MHP A;  1IOX A;  1YO8 A;  3GCW E;  1JV2 B;  3HS7 A;  4ISI L;  1V3X B;  4MMY B;  1YUF A;  1IOE L;  3LN0 A;  4JYV L;  4PH9 A;  3HO3 A;  2RNL A;  1N1I A;  1PFX L;  4NA9 L;  5KN5 C;  1NZI A;  5CIS A;  1HT8 A;  3KK6 A;  3SOV A;  2W2N E;  3TK5 B;  2WZP P;  1SZB A;  2BT7 A;  1EMN A;  1U8C B;  3LTG D;  5CKN A;  1COU A;  2OYE P;  2P3T A;  1NFY B; 
#chains in the Genus database with same CATH homology
 3CA7 A;  2BOU A;  3GCX E;  2WPK E;  1FE2 A;  4Y6D B;  4A7I A;  1NFW B;  1EPJ A;  2UWP B;  1DIY A;  3CS7 L;  2Y5F L;  3HS6 A;  2J95 B;  1NFU B;  1IQG L;  2VVV L;  5JBA E;  5CKM A;  3EGF A;  4D90 A;  4NGA L;  4ZXY L;  2I9B A;  2J2U B;  2EI6 B;  1NPE B;  3CEN L;  1A3P A;  5IKQ A;  1L5G B;  3KL6 B;  1CX2 A;  3MDL A;  1LPK A;  1ZAQ A;  1IQH L;  1LMM A;  5JB8 E;  1ATA A;  1PRH A;  2YGO A;  5E8D A;  1URK A;  2WPI E;  3U73 A;  2PR3 B;  2PUQ L;  5IKV A;  2WFX B;  4LOR A;  3LN1 A;  1IQF L;  1X7A L;  3MQE A;  4BXS A;  1HAF A;  2UWL B;  1P0S L;  2CJI B;  3N8W B;  1HJ7 A;  1MQ6 L;  4CUE A;  1W8B L;  1M1X B;  4Y76 B;  2P3F L;  5JBB E;  6COX A;  5JBC E;  1IVO C;  2FLB L;  2Y5G L;  3KQE L;  3S6X A;  2BOX A;  2VWL L;  1IGX A;  2J4I B;  1FF7 A;  1APQ A;  2YGQ A;  3CFW A;  2W2P E;  2Y81 B;  1PGE A;  1EPH A;  2XBY L;  3SW2 A;  1QFK L;  1G1S A;  2MGP A;  2I9A A;  1F7E A;  2FLG A;  2VWN L;  3GIS X;  4RRW A;  1O5D L;  5I46 L;  1WU1 B;  2BZ6 L;  2WPM E;  1HX2 A;  1LPZ A;  3ZYJ B;  4X8S L;  2WPH E;  1JBU L;  1EMO A;  2BOK L;  1NQL B;  3HO4 A;  2Q1J B;  3QCW A;  5EGM B;  1UZJ A;  1DX5 I;  2WG4 B;  3ZYI B;  1DVA L;  1WHF A;  3N8Z A;  4G1M B;  1IQN L;  1NT0 A;  3BPS E;  1U67 A;  1IQL L;  3TH3 L;  3LC5 B;  5IKR A;  4YT6 L;  1UZK A;  1W7X L;  1HT5 A;  1ADX A;  2WYJ B;  1IQM L;  4M11 A;  1YUG A;  3HPT A;  5IKT A;  1KLO A;  1UZQ A;  1LPG A;  3KCG L;  1RFN B;  3FBY A;  1MQ5 L;  2H9E C;  2JKH L;  3QMO A;  3RR3 A;  2XBW L;  1G2L B;  2XBX L;  4ZH8 B;  2UWO B;  4RRZ A;  4YT7 L;  1KLJ L;  1EBV A;  2VJ3 A;  2Y7X B;  3HS5 A;  2KV4 A;  1C5M F;  2BQ6 A;  3TBD A;  4Y71 B;  4MMZ B;  1EQG A;  4FM5 A;  1FJS L;  1ATE A;  2KB9 A;  4Y7A B;  1K37 A;  2BOH A;  3N8Y A;  2VVU L;  5KIR A;  1G1R A;  1HCG B;  4RRY A;  3KQD L;  2W3K B;  3DEM A;  2F9B L;  3N8X A;  4D0F A;  4E1G A;  1ATD A;  3ELA L;  2M74 A;  1CVW L;  3M37 L;  2VWO L;  4RS0 A;  1HAE A;  1DQB A;  2BQW A;  1HRF A;  4JZD L;  1PTH A;  3F6U L;  3IIT B;  3FCS B;  2EI7 B;  5COX A;  4CUD A;  3NTG A;  1KIG L;  1IGZ A;  2GD4 A;  1F0R B;  3N8W A;  4BDW A;  1XDT R;  1HRE A;  3LTF B;  2WPL E;  1B9W A;  4OTY A;  2FLR L;  3H5C B;  2VH0 B;  4O1Z A;  2D1J B;  1FAX L;  1OB1 C;  1Z6C A;  1AUT L;  3LAQ A;  3LC3 B;  2WG3 C;  3SOB B;  2P28 B;  1HZ8 A;  1EGF A;  4RRX A;  4Y79 B;  5JVY A;  1Z6E L;  2Y7Z B;  2P3U A;  3NJP C;  1CVU A;  3SOQ A;  1Q4G A;  2TGF A;  1KSN B;  5L2Z L;  3V65 B;  4BDX A;  4BXW A;  4ZHA B;  2W2Q E;  4C16 A;  1K36 A;  1P9J A;  2WPJ E;  2P16 L;  3OLT A;  1BF9 A;  3Q3K B;  1DDX A;  1EAI C;  2Y38 A;  4X8V L;  5CKQ A;  1GK5 A;  2FD6 A;  2J94 B;  4ISH L;  1WHE A;  4X8T L;  2XBV L;  2YGP A;  1IQI L;  1JL9 A;  2J38 B;  2RHP A;  2P94 L;  1XKA L;  4Y7B B;  3TZI A;  2W3I B;  3Q7D A;  5L30 L;  1FSB A;  2W2O E;  3N8V A;  1EPG A;  3HO5 A;  5L2Y L;  4XLW A;  1IP0 A;  3NTB A;  3PGH A;  2WFT A;  4BTT A;  1PXX A;  2W86 A;  2BQ7 A;  3FFG L;  2MGR A;  1FFM A;  1CQE A;  1NFX B;  4M10 A;  2DDU A;  2EI8 B;  4ZAE B;  3ENS A;  1APO A;  4YZU B;  4O02 B;  3K9X A;  4BTI A;  4XBM A;  4NG9 L;  3KQC L;  1LMJ A;  5FDQ A;  1G1Q A;  3QH0 A;  4LMF A;  1N7D A;  2G00 L;  2K2T A;  4COX A;  2AYL A;  2VVC K;  3IJE B;  3U7U G;  1FAK L;  5F19 A;  2NPR A;  3BT2 A;  2Y5H L;  2VH6 B;  2BMG A;  2P26 A;  1TOZ A;  3V64 C;  2Y82 B;  3KRK A;  1XKB A;  3N8Y B;  4JZE L;  2P95 L;  2BO2 A;  1XFE A;  3C9A C;  1EQH A;  2K2S B;  1YGC L;  5JB9 E;  1UZP A;  2Y80 B;  4CUF A;  2PHB B;  2OYU P;  4TGF A;  3BT1 A;  3M36 L;  1YUK B;  2ADX A;  2KL7 A;  2J34 B;  1CCV A;  1F0S B;  4Z0L A;  3OLU A;  1IQE L;  1J9C L;  1G2M B;  2VWM K;  3ZYG A;  1G1T A;  3P5B L;  4JZF L;  4Z6A L;  2XC4 L;  5JVZ A;  4Z0K B;  3NT1 A;  2P3F N;  1IQK L;  2FZZ L;  3ASI A;  1TPG A;  4BTU A;  2W2M E;  2H9E L;  1I0U A;  2WYG B;  3R05 A;  4CSY A;  1L3Y A;  5F1A A;  1ATB A;  3LIW B;  1KLI L;  2W26 B;  4X8U L;  4OTJ A;  2KNI A;  2RA0 L;  1IQJ L;  3TGF A;  1CEJ A;  4A94 C;  2B7D L;  2XC0 L;  1MOX C;  3TK6 B;  1TLE A;  2P93 L;  5JW1 A;  3KQB L;  1LQD A;  3POY A;  1F7M A;  4D0E A;  4MMX B;  1IJQ A;  4XL1 A;  5K0H B;  1EPI A;  1CCF A;  1EZQ B;  4RUT A;  4JYU L;  3F1S B;  2XC5 L;  4ZXX L;  4AQT A;  2MHP A;  1IOX A;  1YO8 A;  3GCW E;  1JV2 B;  3HS7 A;  4ISI L;  1V3X B;  4MMY B;  1YUF A;  1IOE L;  3LN0 A;  4JYV L;  4PH9 A;  3HO3 A;  2RNL A;  1N1I A;  1PFX L;  4NA9 L;  5KN5 C;  1NZI A;  5CIS A;  1HT8 A;  3KK6 A;  3SOV A;  2W2N E;  3TK5 B;  2WZP P;  1SZB A;  1EMN A;  1U8C B;  3LTG D;  5CKN A;  1COU A;  2OYE P;  2P3T A;  1NFY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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