2BQWA

Crystal structure of factor xa in complex with compound 45
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold: A Study Combining Structure-Activity Relationship and X-Ray Crystallography.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords COAGULATION FACTOR X
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2005-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2bqwA00
2XC0L 5JW1A 5EGMB 1K37A 2WPME 3KRKA 3N8VA 4X8UL 2PHBB 1HAEA 3GCWE 3TZIA 2B7DL 1NFXB 2J34B 2MHPA 1GK5A 1MQ6L 1X7AL 4RS0A 2EI7B 1DX5I 1YUKB 3NTBA 4Y79B 3LC3B 3U7UG 3BT2A 1G2MB 3MQEA 4MMXB 3ENSA 1ATDA 3KCGL 5CISA 3U73A 3RR3A 3TH3L 5JBAE 2BQWA 1EGFA 1IQML 3OLTA 5KN5C 1IQNL 4OTJA 4Y71B 5CKQA 4BTTA 2P3UA 4BXSA 2DDUA 1FAXL 4RRWA 1XFEA 3LAQA 4G1MB 4CUEA 2Y7ZB 2G00L 3TGFA 1AUTL 5CKMA 2M74A 1IQKL 1O5DL 2Y5FL 2RA0L 5IKVA 1WU1B 4Y7BB 1CVWL 2W26B 1JV2B 1TLEA 1FFMA 3F1SB 1L3YA 1OB1C 1FAKL 2W3KB 1F0SB 2W2OE 4NA9L 1UZQA 2WPIE 4ZHAB 1EAIC 2P16L 4BDWA 1EPGA 1N7DA 2NPRA 2VVVL 2Y5HL 2I9AA 4RRYA 1PTHA 2XC4L 4YZUB 1MQ5L 4BTIA 1IOEL 1LQDA 1YUGA 3DEMA 1ATAA 3ASIA 3KQDL 3HO3A 5CKNA 2VWNL 1IQHL 4Z0KB 1C5MF 1ADXA 1FJSL 2OYEP 2J94B 2WG3C 4XBMA 4D0FA 4X8TL 2W3IB 3CFWA 1KLJL 3NT1A 3CS7L 1WHFA 1IP0A 3QMOA 2FLRL 1CX2A 1EMOA 3QH0A 1WHEA 3C9AC 1IVOC 4LORA 1HAFA 2FD6A 4C16A 1NQLB 3ZYGA 1PGEA 3CENL 4COXA 1IQFL 5IKRA 4OTYA 2P26A 5KIRA 1EZQB 2VWLL 1F0RB 1IQLL 1KLIL 2WPJE 1U67A 4PH9A 4LMFA 3M36L 2Y82B 2BO2A 2VWMK 2Y81B 3ZYIB 2UWOB 1B9WA 4CUFA 2XC5L 2W2ME 3HS6A 4O1ZA 1COUA 4NG9L 3IJEB 2D1JB 2FZZL 4D90A 1TPGA 2J2UB 2FLBL 1EPJA 6COXA 4MMZB 1NFYB 3KQBL 2YGPA 3LN0A 1P0SL 1UZPA 4CSYA 5JB9E 2KL7A 4JZFL 3TK5B 5JVYA 1N1IA 1XDTR 3PGHA 3OLUA 3ELAL 4CUDA 1I0UA 1UZJA 2ADXA 3ZYJB 2BMGA 4ZXXL 4FM5A 1DQBA 3F6UL 1LMJA 1JL9A 1KSNB 1EMNA 3QCWA 2Q1JB 5JVZA 1NFWB 3LN1A 1G1TA 1APOA 1EPIA 3K9XA 2BOHA 5IKTA 2BQ7A 1V3XB 2GD4A 2VH6B 2FLGA 4X8VL 1KLOA 2BOKL 2WYJB 1IQIL 1NFUB 4XL1A 3Q3KB 1XKAL 2WG4B 4AQTA 4BDXA 1G2LB 1Q4GA 1QFKL 3LTFB 3N8WA 1HX2A 4BXWA 4A7IA 1W7XL 4RRXA 1LPZA 4ZXYL 1NPEB 1JBUL 2W2NE 5F1AA 1YO8A 2Y5GL 3KQEL 5L2YL 3FBYA 3LTGD 1F7EA 2WFXB 4BTUA 1CVUA 1FF7A 3Q7DA 3CA7A 3KL6B 2WPKE 1UZKA 2EI8B 3N8YA 1IGZA 2RNLA 1PFXL 2PR3B 1YGCL 5L2ZL 1P9JA 4ZH8B 4YT6L 1HT8A 1NZIA 4JZEL 3SOQA 3POYA 4YT7L 5JBBE 3N8YB 2VVCK 1G1QA 3HPTA 1ATEA 1EBVA 3M37L 5L30L 3TK6B 3HS5A 2YGOA 1CQEA 1EPHA 3EGFA 1J9CL 2P93L 5F19A 3R05A 2BZ6L 1IQGL 2VWOL 1FE2A 1BF9A 2VJ3A 1LPGA 1APQA 2WFTA 1K36A 1U8CB 1YUFA 2Y38A 1EQGA 4E1GA 1HT5A 3SOBB 3LC5B 3FFGL 1F7MA 1Z6CA 5IKQA 2CJIB 1TOZA 1CEJA 3V64C 2KB9A 1PXXA 3KK6A 4M11A 1URKA 2W2PE 1M1XB 4Y7AB 4RUTA 2XBVL 2EI6B 1PRHA 5I46L 4X8SL 2XBXL 1NT0A 4JZDL 2J38B 3V65B 4D0EA 3KQCL 1A3PA 1HRFA 1HCGB 1HREA 3SOVA 3LIWB 3SW2A 3HO4A 2XBYL 1DIYA 1G1RA 2AYLA 3MDLA 4O02B 1HJ7A 2BOXA 1CCVA 2P28B 1EQHA 1CCFA 1SZBA 2UWPB 1ATBA 4Z0LA 3P5BL 1FSBA 4Y76B 2RHPA 3BPSE 2P3FL 3N8XA 1DDXA 2P95L 4Z6AL 4M10A 2OYUP 1IOXA 2MGRA 2VVUL 2BQ6A 2Y7XB 4ZAEB 5JB8E 1IQEL 5FDQA 2WYGB 3NTGA 4JYVL 5COXA 1IQJL 4MMYB 2PUQL 1ZAQA 2P3FN 2P94L 3TBDA 2J4IB 2XBWL 2W86A 3N8WB 1LPKA 2H9EL 2MGPA 2WPLE 3BT1A 5JBCE 1HZ8A 1IGXA 2JKHL 2TGFA 1W8BL 4ISHL 3GCXE 5K0HB 3FCSB 1RFNB 3HS7A 3HO5A 4Y6DB 2F9BL 1IJQA 2K2SB 1DVAL 4ISIL 1KIGL 4JYUL 3N8ZA 1XKBA 2VH0B 5E8DA 4XLWA 1G1SA 2WPHE 2K2TA 3H5CB 1MOXC 2Y80B 2UWLB 3GISX 1Z6EL 1L5GB 4NGAL 2J95B 2I9BA 2W2QE 4RRZA 2P3TA 2BOUA 4TGFA 2KV4A 3IITB 3NJPC
chains in the Genus database with same CATH superfamily
2XC0L 5JW1A 5EGMB 1K37A 2WPME 3KRKA 3N8VA 4X8UL 2PHBB 1HAEA 3GCWE 3TZIA 2B7DL 1NFXB 2J34B 2MHPA 1GK5A 1MQ6L 1X7AL 2BT8A 4RS0A 2EI7B 1DX5I 1YUKB 3NTBA 4Y79B 3LC3B 3U7UG 3BT2A 1G2MB 3MQEA 4MMXB 3ENSA 2WZPP 1ATDA 3KCGL 4GU4A 5CISA 2YGQA 3U73A 3RR3A 3TH3L 5JBAE 2BQWA 1EGFA 1IQML 3OLTA 5KN5C 1IQNL 4OTJA 4Y71B 5CKQA 4BTTA 2P3UA 4BXSA 2DDUA 1FAXL 4RRWA 1XFEA 1KKEA 3LAQA 4G1MB 4CUEA 2Y7ZB 2G00L 1LK9A 3TGFA 1AUTL 5CKMA 2M74A 1IQKL 1O5DL 2Y5FL 2RA0L 5IKVA 1WU1B 4Y7BB 1CVWL 2W26B 1JV2B 1TLEA 1FFMA 3F1SB 1L3YA 1OB1C 1FAKL 2W3KB 1F0SB 2W2OE 4NA9L 1UZQA 2WPIE 4ZHAB 1EAIC 2P16L 4BDWA 1EPGA 1N7DA 2NPRA 2VVVL 2Y5HL 2I9AA 4RRYA 1PTHA 2XC4L 4YZUB 1MQ5L 4BTIA 1IOEL 1LQDA 1YUGA 3DEMA 1ATAA 3ASIA 3KQDL 2HORA 3HO3A 1V1HA 5CKNA 2VWNL 1IQHL 4Z0KB 1C5MF 1ADXA 1FJSL 2OYEP 2J94B 2WG3C 4XBMA 4D0FA 4X8TL 2W3IB 3CFWA 2JJLA 1KLJL 3NT1A 3CS7L 1WHFA 1IP0A 3QMOA 2FLRL 1CX2A 1EMOA 3QH0A 1WHEA 3C9AC 1IVOC 4LORA 2HOXA 1HAFA 2FD6A 4C16A 1NQLB 3ZYGA 1PGEA 3CENL 4COXA 1IQFL 5IKRA 4OTYA 2P26A 5KIRA 1EZQB 2VWLL 1F0RB 1IQLL 1KLIL 2WPJE 1U67A 4GU3A 4PH9A 4LMFA 3M36L 2Y82B 2BO2A 2VWMK 2Y81B 3ZYIB 2UWOB 1B9WA 4CUFA 2XC5L 2W2ME 3HS6A 4O1ZA 1COUA 4NG9L 2H9EC 3IJEB 2D1JB 2FZZL 4D90A 1TPGA 2J2UB 2FLBL 1EPJA 6COXA 4MMZB 1NFYB 3KQBL 2YGPA 3LN0A 1P0SL 1UZPA 4CSYA 5JB9E 2KL7A 4JZFL 3TK5B 5JVYA 1N1IA 1XDTR 3PGHA 3OLUA 3ELAL 4CUDA 1I0UA 1UZJA 2ADXA 3ZYJB 2BMGA 4ZXXL 4FM5A 1DQBA 3F6UL 1LMJA 1JL9A 1KSNB 1EMNA 3QCWA 2Q1JB 5JVZA 1NFWB 3LN1A 1G1TA 1APOA 1EPIA 3K9XA 2BOHA 5IKTA 2BQ7A 1V3XB 2GD4A 2VH6B 2FLGA 4X8VL 1KLOA 2BOKL 2WYJB 1IQIL 1NFUB 4XL1A 3Q3KB 1XKAL 2WG4B 4AQTA 4BDXA 1G2LB 1Q4GA 1QFKL 3LTFB 3N8WA 1HX2A 4BXWA 4A7IA 1W7XL 4RRXA 1LPZA 4ZXYL 1NPEB 1JBUL 2W2NE 5F1AA 1YO8A 2Y5GL 3KQEL 5L2YL 3FBYA 3LTGD 1F7EA 2WFXB 4BTUA 1CVUA 1FF7A 3Q7DA 3CA7A 3KL6B 2WPKE 1UZKA 2EI8B 3N8YA 1IGZA 2RNLA 1PFXL 2PR3B 1YGCL 5L2ZL 1P9JA 4ZH8B 4YT6L 1HT8A 1NZIA 4JZEL 3SOQA 3POYA 4YT7L 5JBBE 3N8YB 2VVCK 1G1QA 3HPTA 1ATEA 1EBVA 3M37L 5L30L 3TK6B 3HS5A 2YGOA 1CQEA 1EPHA 3EGFA 1J9CL 2P93L 5F19A 3R05A 2BZ6L 1IQGL 2VWOL 1FE2A 1BF9A 2VJ3A 1LPGA 1APQA 3S6XA 2WFTA 1K36A 1U8CB 2VRSA 1YUFA 2KNIA 2Y38A 2BT7A 2BSFA 1EQGA 4E1GA 1HT5A 3SOBB 3LC5B 3FFGL 1F7MA 1Z6CA 5IKQA 2CJIB 1TOZA 1CEJA 3V64C 2KB9A 1PXXA 3KK6A 4M11A 1URKA 2W2PE 1M1XB 4Y7AB 4RUTA 2XBVL 2EI6B 1PRHA 5I46L 4X8SL 2XBXL 1NT0A 4JZDL 2J38B 3V65B 4D0EA 3KQCL 1A3PA 1HRFA 1HCGB 1V1IA 1HREA 3SOVA 3LIWB 3SW2A 3HO4A 2XBYL 1DIYA 1G1RA 2AYLA 3MDLA 4O02B 1HJ7A 2BOXA 1CCVA 2P28B 1EQHA 1CCFA 1SZBA 2UWPB 1ATBA 4Z0LA 3P5BL 1FSBA 4Y76B 2RHPA 3BPSE 2P3FL 3N8XA 1DDXA 2P95L 4Z6AL 4M10A 2OYUP 1IOXA 2MGRA 2VVUL 2BQ6A 2Y7XB 4ZAEB 5JB8E 1IQEL 5FDQA 2WYGB 3NTGA 4JYVL 5COXA 1IQJL 4MMYB 2PUQL 1ZAQA 2P3FN 2P94L 3TBDA 2J4IB 2XBWL 2W86A 3N8WB 1LPKA 2H9EL 2MGPA 2WPLE 3BT1A 5JBCE 1HZ8A 1IGXA 2JKHL 2TGFA 1W8BL 4ISHL 3GCXE 5K0HB 3FCSB 1RFNB 3HS7A 1QIUA 3HO5A 4Y6DB 1LMMA 2F9BL 1IJQA 2K2SB 1DVAL 4ISIL 1KIGL 4JYUL 3N8ZA 1XKBA 2VH0B 5E8DA 4XLWA 1G1SA 2WPHE 4A94C 2K2TA 3H5CB 1MOXC 2Y80B 2UWLB 3GISX 1Z6EL 1L5GB 4NGAL 2J95B 2I9BA 2W2QE 4RRZA 2P3TA 2BOUA 4TGFA 2KV4A 3IITB 3NJPC
chains in the Genus database with same CATH topology
2XC0L 5JW1A 5EGMB 1K37A 2WPME 3KRKA 3N8VA 4X8UL 2PHBB 1HAEA 3GCWE 3TZIA 2B7DL 1NFXB 2J34B 2MHPA 1GK5A 1MQ6L 1X7AL 4RS0A 2EI7B 1DX5I 1YUKB 3NTBA 4Y79B 3LC3B 3U7UG 3BT2A 1G2MB 3MQEA 4MMXB 3ENSA 2WZPP 1ATDA 3KCGL 5CISA 2YGQA 3U73A 3RR3A 3TH3L 5JBAE 2BQWA 1EGFA 1IQML 3OLTA 5KN5C 1IQNL 4OTJA 4Y71B 5CKQA 4BTTA 2P3UA 4BXSA 2DDUA 1FAXL 4RRWA 1XFEA 3LAQA 4G1MB 4CUEA 2Y7ZB 2G00L 3TGFA 1AUTL 5CKMA 2M74A 1IQKL 1O5DL 2Y5FL 2RA0L 5IKVA 1WU1B 4Y7BB 1CVWL 2W26B 1JV2B 1TLEA 1FFMA 3F1SB 1L3YA 1OB1C 1FAKL 2W3KB 1F0SB 2W2OE 4NA9L 1UZQA 2WPIE 4ZHAB 1EAIC 2P16L 4BDWA 1EPGA 1N7DA 2NPRA 2VVVL 2Y5HL 2I9AA 4RRYA 1PTHA 2XC4L 4YZUB 1MQ5L 4BTIA 1IOEL 1LQDA 1YUGA 3DEMA 1ATAA 3ASIA 3KQDL 3HO3A 5CKNA 2VWNL 1IQHL 4Z0KB 1C5MF 1ADXA 1FJSL 2OYEP 2J94B 2WG3C 4XBMA 4D0FA 4X8TL 2W3IB 3CFWA 1KLJL 3NT1A 3CS7L 1WHFA 1IP0A 3QMOA 2FLRL 1CX2A 1EMOA 3QH0A 1WHEA 3C9AC 1IVOC 4LORA 1HAFA 2FD6A 4C16A 1NQLB 3ZYGA 1PGEA 3CENL 4COXA 1IQFL 5IKRA 4OTYA 2P26A 5KIRA 1EZQB 2VWLL 1F0RB 1IQLL 1KLIL 2WPJE 1U67A 4PH9A 4LMFA 3M36L 2Y82B 2BO2A 2VWMK 2Y81B 3ZYIB 2UWOB 1B9WA 4CUFA 2XC5L 2W2ME 3HS6A 4O1ZA 1COUA 4NG9L 2H9EC 3IJEB 2D1JB 2FZZL 4D90A 1TPGA 2J2UB 2FLBL 1EPJA 6COXA 4MMZB 1NFYB 3KQBL 2YGPA 3LN0A 1P0SL 1UZPA 4CSYA 5JB9E 2KL7A 4JZFL 3TK5B 5JVYA 1N1IA 1XDTR 3PGHA 3OLUA 3ELAL 4CUDA 1I0UA 1UZJA 2ADXA 3ZYJB 2BMGA 4ZXXL 4FM5A 1DQBA 3F6UL 1LMJA 1JL9A 1KSNB 1EMNA 3QCWA 2Q1JB 5JVZA 1NFWB 3LN1A 1G1TA 1APOA 1EPIA 3K9XA 2BOHA 5IKTA 2BQ7A 1V3XB 2GD4A 2VH6B 2FLGA 4X8VL 1KLOA 2BOKL 2WYJB 1IQIL 1NFUB 4XL1A 3Q3KB 1XKAL 2WG4B 4AQTA 4BDXA 1G2LB 1Q4GA 1QFKL 3LTFB 3N8WA 1HX2A 4BXWA 4A7IA 1W7XL 4RRXA 1LPZA 4ZXYL 1NPEB 1JBUL 2W2NE 5F1AA 1YO8A 2Y5GL 3KQEL 5L2YL 3FBYA 3LTGD 1F7EA 2WFXB 4BTUA 1CVUA 1FF7A 3Q7DA 3CA7A 3KL6B 2WPKE 1UZKA 2EI8B 3N8YA 1IGZA 2RNLA 1PFXL 2PR3B 1YGCL 5L2ZL 1P9JA 4ZH8B 4YT6L 1HT8A 1NZIA 4JZEL 3SOQA 3POYA 4YT7L 5JBBE 3N8YB 2VVCK 1G1QA 3HPTA 1ATEA 1EBVA 3M37L 5L30L 3TK6B 3HS5A 2YGOA 1CQEA 1EPHA 3EGFA 1J9CL 2P93L 5F19A 3R05A 2BZ6L 1IQGL 2VWOL 1FE2A 1BF9A 2VJ3A 1LPGA 1APQA 3S6XA 2WFTA 1K36A 1U8CB 1YUFA 2KNIA 2Y38A 1EQGA 4E1GA 1HT5A 3SOBB 3LC5B 3FFGL 1F7MA 1Z6CA 5IKQA 2CJIB 1TOZA 1CEJA 3V64C 2KB9A 1PXXA 3KK6A 4M11A 1URKA 2W2PE 1M1XB 4Y7AB 4RUTA 2XBVL 2EI6B 1PRHA 5I46L 4X8SL 2XBXL 1NT0A 4JZDL 2J38B 3V65B 4D0EA 3KQCL 1A3PA 1HRFA 1HCGB 1HREA 3SOVA 3LIWB 3SW2A 3HO4A 2XBYL 1DIYA 1G1RA 2AYLA 3MDLA 4O02B 1HJ7A 2BOXA 1CCVA 2P28B 1EQHA 1CCFA 1SZBA 2UWPB 1ATBA 4Z0LA 3P5BL 1FSBA 4Y76B 2RHPA 3BPSE 2P3FL 3N8XA 1DDXA 2P95L 4Z6AL 4M10A 2OYUP 1IOXA 2MGRA 2VVUL 2BQ6A 2Y7XB 4ZAEB 5JB8E 1IQEL 5FDQA 2WYGB 3NTGA 4JYVL 5COXA 1IQJL 4MMYB 2PUQL 1ZAQA 2P3FN 2P94L 3TBDA 2J4IB 2XBWL 2W86A 3N8WB 1LPKA 2H9EL 2MGPA 2WPLE 3BT1A 5JBCE 1HZ8A 1IGXA 2JKHL 2TGFA 1W8BL 4ISHL 3GCXE 5K0HB 3FCSB 1RFNB 3HS7A 3HO5A 4Y6DB 1LMMA 2F9BL 1IJQA 2K2SB 1DVAL 4ISIL 1KIGL 4JYUL 3N8ZA 1XKBA 2VH0B 5E8DA 4XLWA 1G1SA 2WPHE 4A94C 2K2TA 3H5CB 1MOXC 2Y80B 2UWLB 3GISX 1Z6EL 1L5GB 4NGAL 2J95B 2I9BA 2W2QE 4RRZA 2P3TA 2BOUA 4TGFA 2KV4A 3IITB 3NJPC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XC0 L;  5JW1 A;  5EGM B;  1K37 A;  2WPM E;  3KRK A;  3N8V A;  4X8U L;  2PHB B;  1HAE A;  3GCW E;  3TZI A;  2B7D L;  1NFX B;  2J34 B;  2MHP A;  1GK5 A;  1MQ6 L;  1X7A L;  4RS0 A;  2EI7 B;  1DX5 I;  1YUK B;  3NTB A;  4Y79 B;  3LC3 B;  3U7U G;  3BT2 A;  1G2M B;  3MQE A;  4MMX B;  3ENS A;  1ATD A;  3KCG L;  5CIS A;  3U73 A;  3RR3 A;  3TH3 L;  5JBA E;  2BQW A;  1EGF A;  1IQM L;  3OLT A;  5KN5 C;  1IQN L;  4OTJ A;  4Y71 B;  5CKQ A;  4BTT A;  2P3U A;  4BXS A;  2DDU A;  1FAX L;  4RRW A;  1XFE A;  3LAQ A;  4G1M B;  4CUE A;  2Y7Z B;  2G00 L;  3TGF A;  1AUT L;  5CKM A;  2M74 A;  1IQK L;  1O5D L;  2Y5F L;  2RA0 L;  5IKV A;  1WU1 B;  4Y7B B;  1CVW L;  2W26 B;  1JV2 B;  1TLE A;  1FFM A;  3F1S B;  1L3Y A;  1OB1 C;  1FAK L;  2W3K B;  1F0S B;  2W2O E;  4NA9 L;  1UZQ A;  2WPI E;  4ZHA B;  1EAI C;  2P16 L;  4BDW A;  1EPG A;  1N7D A;  2NPR A;  2VVV L;  2Y5H L;  2I9A A;  4RRY A;  1PTH A;  2XC4 L;  4YZU B;  1MQ5 L;  4BTI A;  1IOE L;  1LQD A;  1YUG A;  3DEM A;  1ATA A;  3ASI A;  3KQD L;  3HO3 A;  5CKN A;  2VWN L;  1IQH L;  4Z0K B;  1C5M F;  1ADX A;  1FJS L;  2OYE P;  2J94 B;  2WG3 C;  4XBM A;  4D0F A;  4X8T L;  2W3I B;  3CFW A;  1KLJ L;  3NT1 A;  3CS7 L;  1WHF A;  1IP0 A;  3QMO A;  2FLR L;  1CX2 A;  1EMO A;  3QH0 A;  1WHE A;  3C9A C;  1IVO C;  4LOR A;  1HAF A;  2FD6 A;  4C16 A;  1NQL B;  3ZYG A;  1PGE A;  3CEN L;  4COX A;  1IQF L;  5IKR A;  4OTY A;  2P26 A;  5KIR A;  1EZQ B;  2VWL L;  1F0R B;  1IQL L;  1KLI L;  2WPJ E;  1U67 A;  4PH9 A;  4LMF A;  3M36 L;  2Y82 B;  2BO2 A;  2VWM K;  2Y81 B;  3ZYI B;  2UWO B;  1B9W A;  4CUF A;  2XC5 L;  2W2M E;  3HS6 A;  4O1Z A;  1COU A;  4NG9 L;  3IJE B;  2D1J B;  2FZZ L;  4D90 A;  1TPG A;  2J2U B;  2FLB L;  1EPJ A;  6COX A;  4MMZ B;  1NFY B;  3KQB L;  2YGP A;  3LN0 A;  1P0S L;  1UZP A;  4CSY A;  5JB9 E;  2KL7 A;  4JZF L;  3TK5 B;  5JVY A;  1N1I A;  1XDT R;  3PGH A;  3OLU A;  3ELA L;  4CUD A;  1I0U A;  1UZJ A;  2ADX A;  3ZYJ B;  2BMG A;  4ZXX L;  4FM5 A;  1DQB A;  3F6U L;  1LMJ A;  1JL9 A;  1KSN B;  1EMN A;  3QCW A;  2Q1J B;  5JVZ A;  1NFW B;  3LN1 A;  1G1T A;  1APO A;  1EPI A;  3K9X A;  2BOH A;  5IKT A;  2BQ7 A;  1V3X B;  2GD4 A;  2VH6 B;  2FLG A;  4X8V L;  1KLO A;  2BOK L;  2WYJ B;  1IQI L;  1NFU B;  4XL1 A;  3Q3K B;  1XKA L;  2WG4 B;  4AQT A;  4BDX A;  1G2L B;  1Q4G A;  1QFK L;  3LTF B;  3N8W A;  1HX2 A;  4BXW A;  4A7I A;  1W7X L;  4RRX A;  1LPZ A;  4ZXY L;  1NPE B;  1JBU L;  2W2N E;  5F1A A;  1YO8 A;  2Y5G L;  3KQE L;  5L2Y L;  3FBY A;  3LTG D;  1F7E A;  2WFX B;  4BTU A;  1CVU A;  1FF7 A;  3Q7D A;  3CA7 A;  3KL6 B;  2WPK E;  1UZK A;  2EI8 B;  3N8Y A;  1IGZ A;  2RNL A;  1PFX L;  2PR3 B;  1YGC L;  5L2Z L;  1P9J A;  4ZH8 B;  4YT6 L;  1HT8 A;  1NZI A;  4JZE L;  3SOQ A;  3POY A;  4YT7 L;  5JBB E;  3N8Y B;  2VVC K;  1G1Q A;  3HPT A;  1ATE A;  1EBV A;  3M37 L;  5L30 L;  3TK6 B;  3HS5 A;  2YGO A;  1CQE A;  1EPH A;  3EGF A;  1J9C L;  2P93 L;  5F19 A;  3R05 A;  2BZ6 L;  1IQG L;  2VWO L;  1FE2 A;  1BF9 A;  2VJ3 A;  1LPG A;  1APQ A;  2WFT A;  1K36 A;  1U8C B;  1YUF A;  2Y38 A;  1EQG A;  4E1G A;  1HT5 A;  3SOB B;  3LC5 B;  3FFG L;  1F7M A;  1Z6C A;  5IKQ A;  2CJI B;  1TOZ A;  1CEJ A;  3V64 C;  2KB9 A;  1PXX A;  3KK6 A;  4M11 A;  1URK A;  2W2P E;  1M1X B;  4Y7A B;  4RUT A;  2XBV L;  2EI6 B;  1PRH A;  5I46 L;  4X8S L;  2XBX L;  1NT0 A;  4JZD L;  2J38 B;  3V65 B;  4D0E A;  3KQC L;  1A3P A;  1HRF A;  1HCG B;  1HRE A;  3SOV A;  3LIW B;  3SW2 A;  3HO4 A;  2XBY L;  1DIY A;  1G1R A;  2AYL A;  3MDL A;  4O02 B;  1HJ7 A;  2BOX A;  1CCV A;  2P28 B;  1EQH A;  1CCF A;  1SZB A;  2UWP B;  1ATB A;  4Z0L A;  3P5B L;  1FSB A;  4Y76 B;  2RHP A;  3BPS E;  2P3F L;  3N8X A;  1DDX A;  2P95 L;  4Z6A L;  4M10 A;  2OYU P;  1IOX A;  2MGR A;  2VVU L;  2BQ6 A;  2Y7X B;  4ZAE B;  5JB8 E;  1IQE L;  5FDQ A;  2WYG B;  3NTG A;  4JYV L;  5COX A;  1IQJ L;  4MMY B;  2PUQ L;  1ZAQ A;  2P3F N;  2P94 L;  3TBD A;  2J4I B;  2XBW L;  2W86 A;  3N8W B;  1LPK A;  2H9E L;  2MGP A;  2WPL E;  3BT1 A;  5JBC E;  1HZ8 A;  1IGX A;  2JKH L;  2TGF A;  1W8B L;  4ISH L;  3GCX E;  5K0H B;  3FCS B;  1RFN B;  3HS7 A;  3HO5 A;  4Y6D B;  2F9B L;  1IJQ A;  2K2S B;  1DVA L;  4ISI L;  1KIG L;  4JYU L;  3N8Z A;  1XKB A;  2VH0 B;  5E8D A;  4XLW A;  1G1S A;  2WPH E;  2K2T A;  3H5C B;  1MOX C;  2Y80 B;  2UWL B;  3GIS X;  1Z6E L;  1L5G B;  4NGA L;  2J95 B;  2I9B A;  2W2Q E;  4RRZ A;  2P3T A;  2BOU A;  4TGF A;  2KV4 A;  3IIT B;  3NJP C; 
#chains in the Genus database with same CATH topology
 2XC0 L;  5JW1 A;  5EGM B;  1K37 A;  2WPM E;  3KRK A;  3N8V A;  4X8U L;  2PHB B;  1HAE A;  3GCW E;  3TZI A;  2B7D L;  1NFX B;  2J34 B;  2MHP A;  1GK5 A;  1MQ6 L;  1X7A L;  2BT8 A;  4RS0 A;  2EI7 B;  1DX5 I;  1YUK B;  3NTB A;  4Y79 B;  3LC3 B;  3U7U G;  3BT2 A;  1G2M B;  3MQE A;  4MMX B;  3ENS A;  2WZP P;  1ATD A;  3KCG L;  4GU4 A;  5CIS A;  2YGQ A;  3U73 A;  3RR3 A;  3TH3 L;  5JBA E;  2BQW A;  1EGF A;  1IQM L;  3OLT A;  5KN5 C;  1IQN L;  4OTJ A;  4Y71 B;  5CKQ A;  4BTT A;  2P3U A;  4BXS A;  2DDU A;  1FAX L;  4RRW A;  1XFE A;  1KKE A;  3LAQ A;  4G1M B;  4CUE A;  2Y7Z B;  2G00 L;  1LK9 A;  3TGF A;  1AUT L;  5CKM A;  2M74 A;  1IQK L;  1O5D L;  2Y5F L;  2RA0 L;  5IKV A;  1WU1 B;  4Y7B B;  1CVW L;  2W26 B;  1JV2 B;  1TLE A;  1FFM A;  3F1S B;  1L3Y A;  1OB1 C;  1FAK L;  2W3K B;  1F0S B;  2W2O E;  4NA9 L;  1UZQ A;  2WPI E;  4ZHA B;  1EAI C;  2P16 L;  4BDW A;  1EPG A;  1N7D A;  2NPR A;  2VVV L;  2Y5H L;  2I9A A;  4RRY A;  1PTH A;  2XC4 L;  4YZU B;  1MQ5 L;  4BTI A;  1IOE L;  1LQD A;  1YUG A;  3DEM A;  1ATA A;  3ASI A;  3KQD L;  2HOR A;  3HO3 A;  1V1H A;  5CKN A;  2VWN L;  1IQH L;  4Z0K B;  1C5M F;  1ADX A;  1FJS L;  2OYE P;  2J94 B;  2WG3 C;  4XBM A;  4D0F A;  4X8T L;  2W3I B;  3CFW A;  2JJL A;  1KLJ L;  3NT1 A;  3CS7 L;  1WHF A;  1IP0 A;  3QMO A;  2FLR L;  1CX2 A;  1EMO A;  3QH0 A;  1WHE A;  3C9A C;  1IVO C;  4LOR A;  2HOX A;  1HAF A;  2FD6 A;  4C16 A;  1NQL B;  3ZYG A;  1PGE A;  3CEN L;  4COX A;  1IQF L;  5IKR A;  4OTY A;  2P26 A;  5KIR A;  1EZQ B;  2VWL L;  1F0R B;  1IQL L;  1KLI L;  2WPJ E;  1U67 A;  4GU3 A;  4PH9 A;  4LMF A;  3M36 L;  2Y82 B;  2BO2 A;  2VWM K;  2Y81 B;  3ZYI B;  2UWO B;  1B9W A;  4CUF A;  2XC5 L;  2W2M E;  3HS6 A;  4O1Z A;  1COU A;  4NG9 L;  2H9E C;  3IJE B;  2D1J B;  2FZZ L;  4D90 A;  1TPG A;  2J2U B;  2FLB L;  1EPJ A;  6COX A;  4MMZ B;  1NFY B;  3KQB L;  2YGP A;  3LN0 A;  1P0S L;  1UZP A;  4CSY A;  5JB9 E;  2KL7 A;  4JZF L;  3TK5 B;  5JVY A;  1N1I A;  1XDT R;  3PGH A;  3OLU A;  3ELA L;  4CUD A;  1I0U A;  1UZJ A;  2ADX A;  3ZYJ B;  2BMG A;  4ZXX L;  4FM5 A;  1DQB A;  3F6U L;  1LMJ A;  1JL9 A;  1KSN B;  1EMN A;  3QCW A;  2Q1J B;  5JVZ A;  1NFW B;  3LN1 A;  1G1T A;  1APO A;  1EPI A;  3K9X A;  2BOH A;  5IKT A;  2BQ7 A;  1V3X B;  2GD4 A;  2VH6 B;  2FLG A;  4X8V L;  1KLO A;  2BOK L;  2WYJ B;  1IQI L;  1NFU B;  4XL1 A;  3Q3K B;  1XKA L;  2WG4 B;  4AQT A;  4BDX A;  1G2L B;  1Q4G A;  1QFK L;  3LTF B;  3N8W A;  1HX2 A;  4BXW A;  4A7I A;  1W7X L;  4RRX A;  1LPZ A;  4ZXY L;  1NPE B;  1JBU L;  2W2N E;  5F1A A;  1YO8 A;  2Y5G L;  3KQE L;  5L2Y L;  3FBY A;  3LTG D;  1F7E A;  2WFX B;  4BTU A;  1CVU A;  1FF7 A;  3Q7D A;  3CA7 A;  3KL6 B;  2WPK E;  1UZK A;  2EI8 B;  3N8Y A;  1IGZ A;  2RNL A;  1PFX L;  2PR3 B;  1YGC L;  5L2Z L;  1P9J A;  4ZH8 B;  4YT6 L;  1HT8 A;  1NZI A;  4JZE L;  3SOQ A;  3POY A;  4YT7 L;  5JBB E;  3N8Y B;  2VVC K;  1G1Q A;  3HPT A;  1ATE A;  1EBV A;  3M37 L;  5L30 L;  3TK6 B;  3HS5 A;  2YGO A;  1CQE A;  1EPH A;  3EGF A;  1J9C L;  2P93 L;  5F19 A;  3R05 A;  2BZ6 L;  1IQG L;  2VWO L;  1FE2 A;  1BF9 A;  2VJ3 A;  1LPG A;  1APQ A;  3S6X A;  2WFT A;  1K36 A;  1U8C B;  2VRS A;  1YUF A;  2KNI A;  2Y38 A;  2BT7 A;  2BSF A;  1EQG A;  4E1G A;  1HT5 A;  3SOB B;  3LC5 B;  3FFG L;  1F7M A;  1Z6C A;  5IKQ A;  2CJI B;  1TOZ A;  1CEJ A;  3V64 C;  2KB9 A;  1PXX A;  3KK6 A;  4M11 A;  1URK A;  2W2P E;  1M1X B;  4Y7A B;  4RUT A;  2XBV L;  2EI6 B;  1PRH A;  5I46 L;  4X8S L;  2XBX L;  1NT0 A;  4JZD L;  2J38 B;  3V65 B;  4D0E A;  3KQC L;  1A3P A;  1HRF A;  1HCG B;  1V1I A;  1HRE A;  3SOV A;  3LIW B;  3SW2 A;  3HO4 A;  2XBY L;  1DIY A;  1G1R A;  2AYL A;  3MDL A;  4O02 B;  1HJ7 A;  2BOX A;  1CCV A;  2P28 B;  1EQH A;  1CCF A;  1SZB A;  2UWP B;  1ATB A;  4Z0L A;  3P5B L;  1FSB A;  4Y76 B;  2RHP A;  3BPS E;  2P3F L;  3N8X A;  1DDX A;  2P95 L;  4Z6A L;  4M10 A;  2OYU P;  1IOX A;  2MGR A;  2VVU L;  2BQ6 A;  2Y7X B;  4ZAE B;  5JB8 E;  1IQE L;  5FDQ A;  2WYG B;  3NTG A;  4JYV L;  5COX A;  1IQJ L;  4MMY B;  2PUQ L;  1ZAQ A;  2P3F N;  2P94 L;  3TBD A;  2J4I B;  2XBW L;  2W86 A;  3N8W B;  1LPK A;  2H9E L;  2MGP A;  2WPL E;  3BT1 A;  5JBC E;  1HZ8 A;  1IGX A;  2JKH L;  2TGF A;  1W8B L;  4ISH L;  3GCX E;  5K0H B;  3FCS B;  1RFN B;  3HS7 A;  1QIU A;  3HO5 A;  4Y6D B;  1LMM A;  2F9B L;  1IJQ A;  2K2S B;  1DVA L;  4ISI L;  1KIG L;  4JYU L;  3N8Z A;  1XKB A;  2VH0 B;  5E8D A;  4XLW A;  1G1S A;  2WPH E;  4A94 C;  2K2T A;  3H5C B;  1MOX C;  2Y80 B;  2UWL B;  3GIS X;  1Z6E L;  1L5G B;  4NGA L;  2J95 B;  2I9B A;  2W2Q E;  4RRZ A;  2P3T A;  2BOU A;  4TGF A;  2KV4 A;  3IIT B;  3NJP C; 
#chains in the Genus database with same CATH homology
 2XC0 L;  5JW1 A;  5EGM B;  1K37 A;  2WPM E;  3KRK A;  3N8V A;  4X8U L;  2PHB B;  1HAE A;  3GCW E;  3TZI A;  2B7D L;  1NFX B;  2J34 B;  2MHP A;  1GK5 A;  1MQ6 L;  1X7A L;  4RS0 A;  2EI7 B;  1DX5 I;  1YUK B;  3NTB A;  4Y79 B;  3LC3 B;  3U7U G;  3BT2 A;  1G2M B;  3MQE A;  4MMX B;  3ENS A;  2WZP P;  1ATD A;  3KCG L;  5CIS A;  2YGQ A;  3U73 A;  3RR3 A;  3TH3 L;  5JBA E;  2BQW A;  1EGF A;  1IQM L;  3OLT A;  5KN5 C;  1IQN L;  4OTJ A;  4Y71 B;  5CKQ A;  4BTT A;  2P3U A;  4BXS A;  2DDU A;  1FAX L;  4RRW A;  1XFE A;  3LAQ A;  4G1M B;  4CUE A;  2Y7Z B;  2G00 L;  3TGF A;  1AUT L;  5CKM A;  2M74 A;  1IQK L;  1O5D L;  2Y5F L;  2RA0 L;  5IKV A;  1WU1 B;  4Y7B B;  1CVW L;  2W26 B;  1JV2 B;  1TLE A;  1FFM A;  3F1S B;  1L3Y A;  1OB1 C;  1FAK L;  2W3K B;  1F0S B;  2W2O E;  4NA9 L;  1UZQ A;  2WPI E;  4ZHA B;  1EAI C;  2P16 L;  4BDW A;  1EPG A;  1N7D A;  2NPR A;  2VVV L;  2Y5H L;  2I9A A;  4RRY A;  1PTH A;  2XC4 L;  4YZU B;  1MQ5 L;  4BTI A;  1IOE L;  1LQD A;  1YUG A;  3DEM A;  1ATA A;  3ASI A;  3KQD L;  3HO3 A;  5CKN A;  2VWN L;  1IQH L;  4Z0K B;  1C5M F;  1ADX A;  1FJS L;  2OYE P;  2J94 B;  2WG3 C;  4XBM A;  4D0F A;  4X8T L;  2W3I B;  3CFW A;  1KLJ L;  3NT1 A;  3CS7 L;  1WHF A;  1IP0 A;  3QMO A;  2FLR L;  1CX2 A;  1EMO A;  3QH0 A;  1WHE A;  3C9A C;  1IVO C;  4LOR A;  1HAF A;  2FD6 A;  4C16 A;  1NQL B;  3ZYG A;  1PGE A;  3CEN L;  4COX A;  1IQF L;  5IKR A;  4OTY A;  2P26 A;  5KIR A;  1EZQ B;  2VWL L;  1F0R B;  1IQL L;  1KLI L;  2WPJ E;  1U67 A;  4PH9 A;  4LMF A;  3M36 L;  2Y82 B;  2BO2 A;  2VWM K;  2Y81 B;  3ZYI B;  2UWO B;  1B9W A;  4CUF A;  2XC5 L;  2W2M E;  3HS6 A;  4O1Z A;  1COU A;  4NG9 L;  2H9E C;  3IJE B;  2D1J B;  2FZZ L;  4D90 A;  1TPG A;  2J2U B;  2FLB L;  1EPJ A;  6COX A;  4MMZ B;  1NFY B;  3KQB L;  2YGP A;  3LN0 A;  1P0S L;  1UZP A;  4CSY A;  5JB9 E;  2KL7 A;  4JZF L;  3TK5 B;  5JVY A;  1N1I A;  1XDT R;  3PGH A;  3OLU A;  3ELA L;  4CUD A;  1I0U A;  1UZJ A;  2ADX A;  3ZYJ B;  2BMG A;  4ZXX L;  4FM5 A;  1DQB A;  3F6U L;  1LMJ A;  1JL9 A;  1KSN B;  1EMN A;  3QCW A;  2Q1J B;  5JVZ A;  1NFW B;  3LN1 A;  1G1T A;  1APO A;  1EPI A;  3K9X A;  2BOH A;  5IKT A;  2BQ7 A;  1V3X B;  2GD4 A;  2VH6 B;  2FLG A;  4X8V L;  1KLO A;  2BOK L;  2WYJ B;  1IQI L;  1NFU B;  4XL1 A;  3Q3K B;  1XKA L;  2WG4 B;  4AQT A;  4BDX A;  1G2L B;  1Q4G A;  1QFK L;  3LTF B;  3N8W A;  1HX2 A;  4BXW A;  4A7I A;  1W7X L;  4RRX A;  1LPZ A;  4ZXY L;  1NPE B;  1JBU L;  2W2N E;  5F1A A;  1YO8 A;  2Y5G L;  3KQE L;  5L2Y L;  3FBY A;  3LTG D;  1F7E A;  2WFX B;  4BTU A;  1CVU A;  1FF7 A;  3Q7D A;  3CA7 A;  3KL6 B;  2WPK E;  1UZK A;  2EI8 B;  3N8Y A;  1IGZ A;  2RNL A;  1PFX L;  2PR3 B;  1YGC L;  5L2Z L;  1P9J A;  4ZH8 B;  4YT6 L;  1HT8 A;  1NZI A;  4JZE L;  3SOQ A;  3POY A;  4YT7 L;  5JBB E;  3N8Y B;  2VVC K;  1G1Q A;  3HPT A;  1ATE A;  1EBV A;  3M37 L;  5L30 L;  3TK6 B;  3HS5 A;  2YGO A;  1CQE A;  1EPH A;  3EGF A;  1J9C L;  2P93 L;  5F19 A;  3R05 A;  2BZ6 L;  1IQG L;  2VWO L;  1FE2 A;  1BF9 A;  2VJ3 A;  1LPG A;  1APQ A;  3S6X A;  2WFT A;  1K36 A;  1U8C B;  1YUF A;  2KNI A;  2Y38 A;  1EQG A;  4E1G A;  1HT5 A;  3SOB B;  3LC5 B;  3FFG L;  1F7M A;  1Z6C A;  5IKQ A;  2CJI B;  1TOZ A;  1CEJ A;  3V64 C;  2KB9 A;  1PXX A;  3KK6 A;  4M11 A;  1URK A;  2W2P E;  1M1X B;  4Y7A B;  4RUT A;  2XBV L;  2EI6 B;  1PRH A;  5I46 L;  4X8S L;  2XBX L;  1NT0 A;  4JZD L;  2J38 B;  3V65 B;  4D0E A;  3KQC L;  1A3P A;  1HRF A;  1HCG B;  1HRE A;  3SOV A;  3LIW B;  3SW2 A;  3HO4 A;  2XBY L;  1DIY A;  1G1R A;  2AYL A;  3MDL A;  4O02 B;  1HJ7 A;  2BOX A;  1CCV A;  2P28 B;  1EQH A;  1CCF A;  1SZB A;  2UWP B;  1ATB A;  4Z0L A;  3P5B L;  1FSB A;  4Y76 B;  2RHP A;  3BPS E;  2P3F L;  3N8X A;  1DDX A;  2P95 L;  4Z6A L;  4M10 A;  2OYU P;  1IOX A;  2MGR A;  2VVU L;  2BQ6 A;  2Y7X B;  4ZAE B;  5JB8 E;  1IQE L;  5FDQ A;  2WYG B;  3NTG A;  4JYV L;  5COX A;  1IQJ L;  4MMY B;  2PUQ L;  1ZAQ A;  2P3F N;  2P94 L;  3TBD A;  2J4I B;  2XBW L;  2W86 A;  3N8W B;  1LPK A;  2H9E L;  2MGP A;  2WPL E;  3BT1 A;  5JBC E;  1HZ8 A;  1IGX A;  2JKH L;  2TGF A;  1W8B L;  4ISH L;  3GCX E;  5K0H B;  3FCS B;  1RFN B;  3HS7 A;  3HO5 A;  4Y6D B;  1LMM A;  2F9B L;  1IJQ A;  2K2S B;  1DVA L;  4ISI L;  1KIG L;  4JYU L;  3N8Z A;  1XKB A;  2VH0 B;  5E8D A;  4XLW A;  1G1S A;  2WPH E;  4A94 C;  2K2T A;  3H5C B;  1MOX C;  2Y80 B;  2UWL B;  3GIS X;  1Z6E L;  1L5G B;  4NGA L;  2J95 B;  2I9B A;  2W2Q E;  4RRZ A;  2P3T A;  2BOU A;  4TGF A;  2KV4 A;  3IIT B;  3NJP C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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