2C45A

Native precursor of pyruvoyl dependent aspartate decarboxylase
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
113
structure length
113
Chain Sequence
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of uncleaved L-aspartate-alpha-decarboxylase from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule tags Lyase
source organism Mycobacterium tuberculosis
molecule keywords Aspartate 1-decarboxylase
total genus 27
structure length 113
sequence length 113
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2005-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2c45A00
2DMRA 2VUMA 5FTLA 1PT1A 5C1BA 1H5NA 1OGYA 4D7ZB 5FTJA 4GA5A 1QDNA 2NVYA 1VC3B 2WB1A 3HKZA 1TWAA 3GTKA 2JIPA 3PLXB 5C18A 1DMRA 2VPWA 1S3SA 3QWZA 1E18A 3QQ7A 2E2IA 3DMRA 4RV0A 2JIQA 3QC8A 4AAYA 5DYGA 2JIRA 1TWFA 3TIWA 2B63A 5EPPA 1I3QA 1TMOA 2KI8A 1TWCA 3HU2A 1YLEA 4CRYG 4KDLA 4DMRA 2V3VA 1CZ4A 2YU9A 1G8JA 2JIMA 2VPYA 3OUGA 1SIWA 1DMSA 3GTLA 2PJHB 1H0HA 4QIWA 1Y5IA 1E5VA 3GTOA 1Y1WA 1IW7D 1PYUB 3GTGA 1R9TA 2Y0SA 4AYBA 4CS0A 1CZ5A 1FDOA 1PQEA 2R7ZA 2VPXA 1AA6A 2V45A 4KODA 2JIOA 1PQHA 1Y4ZA 2IV2X 1KQFA 4KDIA 2NYAA 3IR5A 4GA6A 1WLFA 2R93A 1PPYA 2EEOB 1KQGA 3IR7A 2NAPA 3GTMA 1QCSA 1R27A 3TM7B 1SFOA 1PQFA 2E7ZA 4C2MA 1E61A 1PT0A 1CR5A 3H0GA 1TWGA 1UHDA 3GTJA 2JA6A 1E32A 5FTNA 4AONB 3CQZA 5T5ID 1TWHA 3HU3A 2E2HA 3IR6A 5B6CA 1R7RA 3FKIA 5FTMA 3ML1A 1I50A 1WCMA 5GLFA 1PYQA 1AW8B 4AOKB 4KLNA 1EU1A 2NVXA 5T5MD 4KO8A 4AZDA 2WAQA 2JA7A 3GTQA 3CF2A 2JA5A 3HU1A 1UHEA 3GTPA 5DYIA 1FDIA 1K83A 1Y1VA 2C45A 1G8KA 1E60A 2VPZA 2R92A 3QQ8A 2PMZA 1Q16A 4CRZA 5FTKA 3O5AA
chains in the Genus database with same CATH superfamily
5GLYA 1BW4A 2DMRA 2VUMA 5FTLA 3X2OA 4FERA 1PT1A 5C1BA 2A69D 2PI8A 1H5NA 1OGYA 4D7ZB 5FTJA 4JP7A 5GM9A 4GA5A 1QDNA 2NVYA 4NOHA 1VC3B 2HCZX 2WB1A 3HKZA 5H4UA 1TWAA 1YNJD 3GTKA 2JIPA 3PLXB 5C18A 1DMRA 2VPWA 4JCWA 1S3SA 3QWZA 1E18A 2PJJA 3QQ7A 2E2IA 3DMRA 4RV0A 2JIQA 3QC8A 2G6GA 4AAYA 1L8FA 1YNND 5DYGA 2JIRA 1TWFA 2PNWA 3X2PA 3TIWA 2B63A 4ZM7A 5EPPA 1I3QA 1TMOA 2KI8A 1TWCA 3HU2A 1YLEA 2ENGA 4CRYG 4KDLA 4DMRA 3X2KA 2V3VA 1CZ4A 2YU9A 1G8JA 4FFTA 2BE5D 2A68D 2JIMA 2VPYA 3OUGA 3SULA 3X2LA 1SIWA 1DMSA 3M3GA 3GTLA 2PJHB 1H0HA 4QIWA 1Y5IA 1E5VA 3GTOA 1Y1WA 1IW7D 1PYUB 3GTGA 3ENGA 1R9TA 2Y0SA 4AYBA 4CS0A 1CZ5A 1FDOA 3SUJA 2GAEA 1OA7A 1PQEA 2R7ZA 2VPXA 1AA6A 2V45A 3X2IA 4JP6A 2JIOA 4KODA 1PQHA 1Y4ZA 3X2MA 2O5JD 2IV2X 1KQFA 4KDIA 2NYAA 3IR5A 4GA6A 1WLFA 2R93A 1PPYA 3X2JA 2EEOB 4FG4A 4AVRA 3IR7A 1HD5A 1KQGA 2A6ED 4FG2A 3D30A 2AE0X 4JS7A 3SUKA 4L48A 2NAPA 3GTMA 1QCSA 1R27A 1BW3A 3TM7B 1ZYRD 2CW0D 1SFOA 1PQFA 2E7ZA 4C2MA 1E61A 1PT0A 1CR5A 3H0GA 1TWGA 5GLXA 1UHDA 3GTJA 2JA6A 1E32A 5FTNA 2KQAA 4AONB 2BH0A 2G5DA 3CQZA 5T5ID 1TWHA 3HU3A 2E2HA 3IR6A 5B6CA 1R7RA 3FKIA 5FTMA 3X2NA 3ML1A 1WC2A 1I50A 3CZBA 1WCMA 5GLFA 1PYQA 1ZC1A 1AW8B 2PICA 4JJOA 4KLNA 1EU1A 4AOKB 2YUJA 2NVXA 3X2GA 5T5MD 4KO8A 4AZDA 2WAQA 2JA7A 1SMYD 1N10A 3GTQA 3CF2A 4ENGA 1OA9A 2JA5A 3HU1A 1UHEA 3GTPA 5DYIA 1FDIA 2A6HD 1K83A 3SUMA 1Y1VA 3X2HA 2C45A 1G8KA 1E60A 2VPZA 2R92A 3QQ8A 2PMZA 1Q16A 4CRZA 5FTKA 3O5AA
chains in the Genus database with same CATH topology
2DMRA 2VUMA 5FTLA 1PT1A 5C1BA 2A69D 2PI8A 1H5NA 1OGYA 4D7ZB 5FTJA 4GA5A 1QDNA 2NVYA 4NOHA 1VC3B 2WB1A 3HKZA 1TWAA 1YNJD 3GTKA 2JIPA 3PLXB 5C18A 1DMRA 2VPWA 1S3SA 3QWZA 1E18A 2PJJA 3QQ7A 2E2IA 3DMRA 4RV0A 2JIQA 3QC8A 2G6GA 4AAYA 1YNND 5DYGA 2JIRA 1TWFA 2PNWA 3TIWA 2B63A 5EPPA 1I3QA 1TMOA 2KI8A 1TWCA 3HU2A 1YLEA 4CRYG 4KDLA 4DMRA 2V3VA 1CZ4A 2YU9A 1G8JA 2BE5D 2A68D 2JIMA 2VPYA 3OUGA 1SIWA 1DMSA 3GTLA 2PJHB 1H0HA 4QIWA 1Y5IA 1E5VA 3GTOA 1Y1WA 1IW7D 1PYUB 3GTGA 1R9TA 2Y0SA 4AYBA 4CS0A 1CZ5A 1FDOA 2GAEA 1PQEA 2R7ZA 2VPXA 1AA6A 2V45A 4KODA 2JIOA 1PQHA 1Y4ZA 2O5JD 2IV2X 1KQFA 4KDIA 2NYAA 3IR5A 4GA6A 1WLFA 2R93A 1PPYA 2EEOB 1KQGA 3IR7A 2A6ED 2AE0X 2NAPA 3GTMA 1QCSA 1R27A 3TM7B 1ZYRD 2CW0D 1SFOA 1PQFA 2E7ZA 4C2MA 1E61A 1PT0A 1CR5A 3H0GA 1TWGA 1UHDA 3GTJA 2JA6A 1E32A 5FTNA 4AONB 2G5DA 3CQZA 5T5ID 1TWHA 3HU3A 2E2HA 3IR6A 5B6CA 1R7RA 3FKIA 5FTMA 3ML1A 1I50A 3CZBA 1WCMA 5GLFA 1PYQA 1ZC1A 1AW8B 2PICA 4AOKB 4KLNA 1EU1A 2YUJA 2NVXA 5T5MD 4KO8A 4AZDA 2WAQA 2JA7A 1SMYD 3GTQA 3CF2A 2JA5A 3HU1A 1UHEA 3GTPA 5DYIA 1FDIA 2A6HD 1K83A 1Y1VA 2C45A 1G8KA 1E60A 2VPZA 2R92A 3QQ8A 2PMZA 1Q16A 4CRZA 5FTKA 3O5AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DMR A;  2VUM A;  5FTL A;  1PT1 A;  5C1B A;  1H5N A;  1OGY A;  4D7Z B;  5FTJ A;  4GA5 A;  1QDN A;  2NVY A;  1VC3 B;  2WB1 A;  3HKZ A;  1TWA A;  3GTK A;  2JIP A;  3PLX B;  5C18 A;  1DMR A;  2VPW A;  1S3S A;  3QWZ A;  1E18 A;  3QQ7 A;  2E2I A;  3DMR A;  4RV0 A;  2JIQ A;  3QC8 A;  4AAY A;  5DYG A;  2JIR A;  1TWF A;  3TIW A;  2B63 A;  5EPP A;  1I3Q A;  1TMO A;  2KI8 A;  1TWC A;  3HU2 A;  1YLE A;  4CRY G;  4KDL A;  4DMR A;  2V3V A;  1CZ4 A;  2YU9 A;  1G8J A;  2JIM A;  2VPY A;  3OUG A;  1SIW A;  1DMS A;  3GTL A;  2PJH B;  1H0H A;  4QIW A;  1Y5I A;  1E5V A;  3GTO A;  1Y1W A;  1IW7 D;  1PYU B;  3GTG A;  1R9T A;  2Y0S A;  4AYB A;  4CS0 A;  1CZ5 A;  1FDO A;  1PQE A;  2R7Z A;  2VPX A;  1AA6 A;  2V45 A;  4KOD A;  2JIO A;  1PQH A;  1Y4Z A;  2IV2 X;  1KQF A;  4KDI A;  2NYA A;  3IR5 A;  4GA6 A;  1WLF A;  2R93 A;  1PPY A;  2EEO B;  1KQG A;  3IR7 A;  2NAP A;  3GTM A;  1QCS A;  1R27 A;  3TM7 B;  1SFO A;  1PQF A;  2E7Z A;  4C2M A;  1E61 A;  1PT0 A;  1CR5 A;  3H0G A;  1TWG A;  1UHD A;  3GTJ A;  2JA6 A;  1E32 A;  5FTN A;  4AON B;  3CQZ A;  5T5I D;  1TWH A;  3HU3 A;  2E2H A;  3IR6 A;  5B6C A;  1R7R A;  3FKI A;  5FTM A;  3ML1 A;  1I50 A;  1WCM A;  5GLF A;  1PYQ A;  1AW8 B;  4AOK B;  4KLN A;  1EU1 A;  2NVX A;  5T5M D;  4KO8 A;  4AZD A;  2WAQ A;  2JA7 A;  3GTQ A;  3CF2 A;  2JA5 A;  3HU1 A;  1UHE A;  3GTP A;  5DYI A;  1FDI A;  1K83 A;  1Y1V A;  2C45 A;  1G8K A;  1E60 A;  2VPZ A;  2R92 A;  3QQ8 A;  2PMZ A;  1Q16 A;  4CRZ A;  5FTK A;  3O5A A; 
#chains in the Genus database with same CATH topology
 5GLY A;  1BW4 A;  2DMR A;  2VUM A;  5FTL A;  3X2O A;  4FER A;  1PT1 A;  5C1B A;  2A69 D;  2PI8 A;  1H5N A;  1OGY A;  4D7Z B;  5FTJ A;  4JP7 A;  5GM9 A;  4GA5 A;  1QDN A;  2NVY A;  4NOH A;  1VC3 B;  2HCZ X;  2WB1 A;  3HKZ A;  5H4U A;  1TWA A;  1YNJ D;  3GTK A;  2JIP A;  3PLX B;  5C18 A;  1DMR A;  2VPW A;  4JCW A;  1S3S A;  3QWZ A;  1E18 A;  2PJJ A;  3QQ7 A;  2E2I A;  3DMR A;  4RV0 A;  2JIQ A;  3QC8 A;  2G6G A;  4AAY A;  1L8F A;  1YNN D;  5DYG A;  2JIR A;  1TWF A;  2PNW A;  3X2P A;  3TIW A;  2B63 A;  4ZM7 A;  5EPP A;  1I3Q A;  1TMO A;  2KI8 A;  1TWC A;  3HU2 A;  1YLE A;  2ENG A;  4CRY G;  4KDL A;  4DMR A;  3X2K A;  2V3V A;  1CZ4 A;  2YU9 A;  1G8J A;  4FFT A;  2BE5 D;  2A68 D;  2JIM A;  2VPY A;  3OUG A;  3SUL A;  3X2L A;  1SIW A;  1DMS A;  3M3G A;  3GTL A;  2PJH B;  1H0H A;  4QIW A;  1Y5I A;  1E5V A;  3GTO A;  1Y1W A;  1IW7 D;  1PYU B;  3GTG A;  3ENG A;  1R9T A;  2Y0S A;  4AYB A;  4CS0 A;  1CZ5 A;  1FDO A;  3SUJ A;  2GAE A;  1OA7 A;  1PQE A;  2R7Z A;  2VPX A;  1AA6 A;  2V45 A;  3X2I A;  4JP6 A;  2JIO A;  4KOD A;  1PQH A;  1Y4Z A;  3X2M A;  2O5J D;  2IV2 X;  1KQF A;  4KDI A;  2NYA A;  3IR5 A;  4GA6 A;  1WLF A;  2R93 A;  1PPY A;  3X2J A;  2EEO B;  4FG4 A;  4AVR A;  3IR7 A;  1HD5 A;  1KQG A;  2A6E D;  4FG2 A;  3D30 A;  2AE0 X;  4JS7 A;  3SUK A;  4L48 A;  2NAP A;  3GTM A;  1QCS A;  1R27 A;  1BW3 A;  3TM7 B;  1ZYR D;  2CW0 D;  1SFO A;  1PQF A;  2E7Z A;  4C2M A;  1E61 A;  1PT0 A;  1CR5 A;  3H0G A;  1TWG A;  5GLX A;  1UHD A;  3GTJ A;  2JA6 A;  1E32 A;  5FTN A;  2KQA A;  4AON B;  2BH0 A;  2G5D A;  3CQZ A;  5T5I D;  1TWH A;  3HU3 A;  2E2H A;  3IR6 A;  5B6C A;  1R7R A;  3FKI A;  5FTM A;  3X2N A;  3ML1 A;  1WC2 A;  1I50 A;  3CZB A;  1WCM A;  5GLF A;  1PYQ A;  1ZC1 A;  1AW8 B;  2PIC A;  4JJO A;  4KLN A;  1EU1 A;  4AOK B;  2YUJ A;  2NVX A;  3X2G A;  5T5M D;  4KO8 A;  4AZD A;  2WAQ A;  2JA7 A;  1SMY D;  1N10 A;  3GTQ A;  3CF2 A;  4ENG A;  1OA9 A;  2JA5 A;  3HU1 A;  1UHE A;  3GTP A;  5DYI A;  1FDI A;  2A6H D;  1K83 A;  3SUM A;  1Y1V A;  3X2H A;  2C45 A;  1G8K A;  1E60 A;  2VPZ A;  2R92 A;  3QQ8 A;  2PMZ A;  1Q16 A;  4CRZ A;  5FTK A;  3O5A A; 
#chains in the Genus database with same CATH homology
 2DMR A;  2VUM A;  5FTL A;  1PT1 A;  5C1B A;  2A69 D;  2PI8 A;  1H5N A;  1OGY A;  4D7Z B;  5FTJ A;  4GA5 A;  1QDN A;  2NVY A;  4NOH A;  1VC3 B;  2WB1 A;  3HKZ A;  1TWA A;  1YNJ D;  3GTK A;  2JIP A;  3PLX B;  5C18 A;  1DMR A;  2VPW A;  1S3S A;  3QWZ A;  1E18 A;  2PJJ A;  3QQ7 A;  2E2I A;  3DMR A;  4RV0 A;  2JIQ A;  3QC8 A;  2G6G A;  4AAY A;  1YNN D;  5DYG A;  2JIR A;  1TWF A;  2PNW A;  3TIW A;  2B63 A;  5EPP A;  1I3Q A;  1TMO A;  2KI8 A;  1TWC A;  3HU2 A;  1YLE A;  4CRY G;  4KDL A;  4DMR A;  2V3V A;  1CZ4 A;  2YU9 A;  1G8J A;  2BE5 D;  2A68 D;  2JIM A;  2VPY A;  3OUG A;  1SIW A;  1DMS A;  3GTL A;  2PJH B;  1H0H A;  4QIW A;  1Y5I A;  1E5V A;  3GTO A;  1Y1W A;  1IW7 D;  1PYU B;  3GTG A;  1R9T A;  2Y0S A;  4AYB A;  4CS0 A;  1CZ5 A;  1FDO A;  2GAE A;  1PQE A;  2R7Z A;  2VPX A;  1AA6 A;  2V45 A;  4KOD A;  2JIO A;  1PQH A;  1Y4Z A;  2O5J D;  2IV2 X;  1KQF A;  4KDI A;  2NYA A;  3IR5 A;  4GA6 A;  1WLF A;  2R93 A;  1PPY A;  2EEO B;  1KQG A;  3IR7 A;  2A6E D;  2AE0 X;  2NAP A;  3GTM A;  1QCS A;  1R27 A;  3TM7 B;  1ZYR D;  2CW0 D;  1SFO A;  1PQF A;  2E7Z A;  4C2M A;  1E61 A;  1PT0 A;  1CR5 A;  3H0G A;  1TWG A;  1UHD A;  3GTJ A;  2JA6 A;  1E32 A;  5FTN A;  4AON B;  2G5D A;  3CQZ A;  5T5I D;  1TWH A;  3HU3 A;  2E2H A;  3IR6 A;  5B6C A;  1R7R A;  3FKI A;  5FTM A;  3ML1 A;  1I50 A;  3CZB A;  1WCM A;  5GLF A;  1PYQ A;  1ZC1 A;  1AW8 B;  2PIC A;  4AOK B;  4KLN A;  1EU1 A;  2YUJ A;  2NVX A;  5T5M D;  4KO8 A;  4AZD A;  2WAQ A;  2JA7 A;  1SMY D;  3GTQ A;  3CF2 A;  2JA5 A;  3HU1 A;  1UHE A;  3GTP A;  5DYI A;  1FDI A;  2A6H D;  1K83 A;  1Y1V A;  2C45 A;  1G8K A;  1E60 A;  2VPZ A;  2R92 A;  3QQ8 A;  2PMZ A;  1Q16 A;  4CRZ A;  5FTK A;  3O5A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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