2FZZL

Factor xa in complex with the inhibitor 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(2'-(((3r)-3-hydroxy-1-pyrrolidinyl)methyl)-4-biphenylyl)-3-(trifluoromethyl)-1,4,5,6-tetrahydro-7h-pyrazolo[3,4-c]pyridin-7-one
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Coagulation factor X
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2006-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2fzzL00
2DDUA 3H5CB 4Y79B 2BMGA 2EI8B 2FD6A 4Z0LA 4BTTA 1UZPA 2BOHA 3Q7DA 1HCGB 3TK6B 3ENSA 1N7DA 4Y7BB 1ADXA 1IGXA 2KL7A 1KLOA 1CCFA 3QH0A 1IOXA 1HX2A 1G1QA 2BQ7A 2J2UB 2XC4L 4Y7AB 4ZXXL 3MDLA 1F7EA 3NTGA 4YT7L 3KRKA 3KL6B 3V64C 1XKAL 4O1ZA 1LMJA 1Q4GA 3GISX 1U67A 2WG4B 3BT1A 1TPGA 4BXWA 1X7AL 4BTUA 1TOZA 1IQKL 1FAKL 4ZHAB 1A3PA 4PH9A 5F19A 2Y7ZB 4JYVL 3NT1A 2MHPA 2KV4A 4X8UL 1J9CL 1G1RA 2TGFA 2J4IB 3HO5A 2J95B 2P3UA 1IQML 1I0UA 1URKA 1GK5A 1K37A 3HS7A 2WYJB 3ELAL 3M37L 4ZH8B 3N8WB 1NT0A 4O02B 4JZEL 1CCVA 1MQ6L 1TLEA 3LC3B 3R05A 1G2MB 4M10A 4TGFA 5I46L 1C5MF 1QFKL 2UWPB 4OTYA 3IITB 1Z6CA 1W8BL 3V65B 4X8VL 3NTBA 1HZ8A 4XBMA 1EPIA 2WYGB 1P9JA 4NG9L 5FDQA 1NFWB 5CKNA 5IKVA 2MGRA 3DEMA 2B7DL 3ASIA 3ZYIB 4G1MB 2FLBL 3KQEL 2VWNL 1IQIL 2Y5GL 2WPME 4D0FA 1IJQA 3ZYJB 5IKQA 2UWOB 1O5DL 1IQLL 3C9AC 3M36L 1DX5I 2XBXL 1CVUA 2M74A 2NPRA 1IQHL 4JYUL 6COXA 2P3TA 5KIRA 1G1SA 4LORA 2W3KB 1IP0A 1PRHA 3NJPC 5E8DA 2P95L 5IKRA 5L30L 2MGPA 1NFYB 5CISA 3FCSB 4M11A 3HO4A 3U73A 1ATDA 5JBBE 1APQA 5JBAE 4X8TL 4RRXA 1K36A 2VVUL 2XBVL 1DIYA 3LIWB 2W86A 1HT8A 1XFEA 1JV2B 1CVWL 2P94L 3LN0A 3PGHA 3LC5B 4ISHL 2W2QE 2H9EL 1LPZA 2D1JB 1ZAQA 2W2ME 4JZFL 3K9XA 2PHBB 3KK6A 1HAFA 3U7UG 2WFTA 4NGAL 4Z6AL 3F1SB 4FM5A 4ISIL 2W2PE 4BDXA 4C16A 5CKMA 5JVZA 4OTJA 2EI7B 2VH0B 4XL1A 2Y5FL 1NZIA 1EZQB 2WG3C 2WPIE 4MMZB 5CKQA 1CX2A 4A7IA 1SZBA 1EMNA 1M1XB 2Y80B 1FF7A 2I9BA 2P28B 3SOVA 2CJIB 2EI6B 3CS7L 4CUEA 2Y7XB 5COXA 1YO8A 1CEJA 2UWLB 3BT2A 3KCGL 2PR3B 3QCWA 2I9AA 3SOBB 2FLRL 2YGPA 5L2YL 4YZUB 4COXA 4JZDL 2OYEP 2XBWL 4MMYB 1MQ5L 2BQ6A 2P16L 1LPGA 1XDTR 3TH3L 1ATBA 2P3FN 2Y5HL 1G1TA 3MQEA 2RNLA 2XBYL 2BZ6L 2RA0L 3Q3KB 2PUQL 2VJ3A 1WHEA 1MOXC 2Y38A 4YT6L 3POYA 5K0HB 1HRFA 3HO3A 2WPJE 3N8ZA 1UZJA 2P93L 1COUA 1EQHA 3QMOA 4ZXYL 2G00L 3F6UL 4XLWA 4Y71B 3TBDA 3LTGD 1CQEA 2P26A 1IQEL 1JL9A 2W2NE 2J34B 1LPKA 1OB1C 3BPSE 3CFWA 2W26B 2K2SB 2BOKL 2BOXA 1DDXA 3N8YA 1PFXL 5JBCE 1FFMA 1EGFA 1IGZA 1KLIL 1IQJL 4AQTA 4RRYA 1ATAA 3OLUA 2WFXB 2W3IB 5EGMB 1IQGL 1HT5A 1KLJL 1B9WA 2YGOA 1EPGA 1DQBA 3SOQA 2Y81B 1DVAL 2Q1JB 4RRWA 2BO2A 2XC5L 3LAQA 3TGFA 1PXXA 1ATEA 4RRZA 1RFNB 1IOEL 1EPJA 1W7XL 2AYLA 3CENL 3GCXE 1HJ7A 2JKHL 1F7MA 2FZZL 3EGFA 1UZKA 4MMXB 4CUFA 2Y82B 3P5BL 3GCWE 1F0RB 3N8VA 4BTIA 5F1AA 1FSBA 1IVOC 3LN1A 1HAEA 1KIGL 5JB8E 1N1IA 4Z0KB 3TZIA 3FFGL 4D0EA 1UZQA 2RHPA 2FLGA 1BF9A 3KQBL 2XC0L 1U8CB 4Y76B 3KQDL 1FE2A 2KB9A 1EMOA 1EPHA 1YUFA 3FBYA 1EBVA 2OYUP 3RR3A 1P0SL 3CA7A 1V3XB 4CUDA 1XKBA 4CSYA 1NFUB 4X8SL 4ZAEB 4RS0A 4Y6DB 2J94B 2GD4A 1KSNB 5KN5C 5L2ZL 1NQLB 3TK5B 1IQFL 4LMFA 5IKTA 1AUTL 1APOA 3SW2A 4RUTA 2BQWA 1PTHA 2K2TA 4D90A 2ADXA 3IJEB 3N8YB 2J38B 3LTFB 1NFXB 1LQDA 2W2OE 1YUGA 1EQGA 1L3YA 5JVYA 3HPTA 1YUKB 2VWMK 4BXSA 1WU1B 1YGCL 4BDWA 2WPHE 5JW1A 2VWLL 1JBUL 1HREA 2VVCK 1FJSL 1EAIC 2WPKE 1IQNL 3N8WA 1Z6EL 2BOUA 2VWOL 3OLTA 2WPLE 3KQCL 3ZYGA 3HS5A 3N8XA 1PGEA 2F9BL 5JB9E 1FAXL 2VH6B 4E1GA 1G2LB 1NPEB 2P3FL 3HS6A 4NA9L 1WHFA 1F0SB 2VVVL 1L5GB
chains in the Genus database with same CATH superfamily
2DDUA 3H5CB 4Y79B 2BMGA 2YGQA 2EI8B 2FD6A 4Z0LA 4BTTA 1UZPA 2BOHA 3Q7DA 1HCGB 3TK6B 3ENSA 1N7DA 4Y7BB 1ADXA 1IGXA 2KL7A 1KLOA 1CCFA 3QH0A 1IOXA 1HX2A 1G1QA 2BQ7A 2J2UB 2XC4L 4Y7AB 4ZXXL 3MDLA 1F7EA 3NTGA 4YT7L 3KRKA 3KL6B 3V64C 1XKAL 4O1ZA 1LMJA 1Q4GA 3GISX 1U67A 2WG4B 3BT1A 1TPGA 4BXWA 1X7AL 4BTUA 1TOZA 1IQKL 1FAKL 4ZHAB 1A3PA 4PH9A 5F19A 2Y7ZB 4JYVL 3NT1A 2MHPA 2KV4A 4X8UL 1J9CL 1G1RA 2TGFA 2J4IB 3HO5A 2J95B 2P3UA 1IQML 1I0UA 1URKA 1GK5A 1K37A 3HS7A 2WYJB 3ELAL 3M37L 4ZH8B 3N8WB 1NT0A 4O02B 4JZEL 1CCVA 1MQ6L 1TLEA 3LC3B 2BT8A 3R05A 1G2MB 4M10A 4TGFA 5I46L 1C5MF 1QFKL 2UWPB 4OTYA 3IITB 1Z6CA 1W8BL 3V65B 4X8VL 3NTBA 1HZ8A 4XBMA 1EPIA 2WYGB 1P9JA 4NG9L 5FDQA 1NFWB 5CKNA 5IKVA 2MGRA 3DEMA 2B7DL 3ASIA 3ZYIB 4G1MB 2FLBL 3KQEL 2VWNL 1IQIL 2Y5GL 2WPME 4D0FA 1IJQA 3ZYJB 5IKQA 2UWOB 1O5DL 1IQLL 3C9AC 3M36L 1DX5I 2XBXL 1CVUA 2M74A 2NPRA 1IQHL 4JYUL 6COXA 2P3TA 5KIRA 1G1SA 4LORA 2W3KB 1IP0A 1PRHA 3NJPC 5E8DA 2P95L 5IKRA 5L30L 2MGPA 1NFYB 5CISA 3FCSB 4M11A 3HO4A 3U73A 1ATDA 5JBBE 1APQA 5JBAE 4X8TL 4RRXA 1K36A 2VVUL 2XBVL 1DIYA 3LIWB 2W86A 1HT8A 1XFEA 1JV2B 1CVWL 2P94L 3LN0A 3PGHA 3LC5B 4ISHL 2W2QE 2H9EL 1LPZA 2D1JB 1ZAQA 2W2ME 4JZFL 3K9XA 2PHBB 2HOXA 3KK6A 1HAFA 3U7UG 2WFTA 4NGAL 4Z6AL 3F1SB 4FM5A 2WZPP 4ISIL 2W2PE 4BDXA 4C16A 5CKMA 5JVZA 4OTJA 2EI7B 1QIUA 2VH0B 4XL1A 2Y5FL 1NZIA 1EZQB 2WG3C 2WPIE 4MMZB 5CKQA 1CX2A 4A7IA 1SZBA 1EMNA 1M1XB 2Y80B 1FF7A 2I9BA 2P28B 3SOVA 2CJIB 2EI6B 3CS7L 4CUEA 2Y7XB 5COXA 1YO8A 1CEJA 2UWLB 1LK9A 3BT2A 3KCGL 2PR3B 3QCWA 2I9AA 3SOBB 2BT7A 2FLRL 2YGPA 5L2YL 4YZUB 4A94C 4COXA 4JZDL 2H9EC 2OYEP 2XBWL 4MMYB 1MQ5L 2BQ6A 2P16L 1LPGA 1XDTR 3TH3L 1ATBA 2P3FN 2Y5HL 1G1TA 4GU3A 3MQEA 2RNLA 2XBYL 2BZ6L 2RA0L 2BSFA 3Q3KB 2PUQL 2VJ3A 1WHEA 2VRSA 1MOXC 2Y38A 4YT6L 3POYA 5K0HB 1HRFA 3HO3A 2WPJE 3N8ZA 1UZJA 2P93L 1COUA 1EQHA 3QMOA 4ZXYL 1LMMA 2G00L 3F6UL 4XLWA 4Y71B 3TBDA 3LTGD 1CQEA 2P26A 3S6XA 1IQEL 1JL9A 2W2NE 2J34B 1LPKA 2JJLA 1OB1C 3BPSE 3CFWA 2W26B 2K2SB 2BOKL 2BOXA 1DDXA 3N8YA 1PFXL 5JBCE 1FFMA 1EGFA 1IGZA 1KLIL 1IQJL 4AQTA 1V1HA 4RRYA 1ATAA 3OLUA 2WFXB 2W3IB 5EGMB 1IQGL 1HT5A 1KLJL 1B9WA 2YGOA 1EPGA 1DQBA 3SOQA 2Y81B 1DVAL 2Q1JB 4RRWA 2BO2A 2XC5L 3LAQA 3TGFA 1PXXA 1ATEA 4RRZA 1RFNB 1IOEL 1EPJA 1W7XL 2AYLA 3CENL 3GCXE 1HJ7A 2JKHL 1F7MA 2FZZL 3EGFA 1UZKA 2KNIA 4MMXB 4CUFA 2Y82B 3P5BL 3GCWE 1F0RB 3N8VA 4BTIA 5F1AA 1FSBA 1IVOC 3LN1A 1HAEA 1KIGL 5JB8E 1N1IA 1KKEA 4Z0KB 3TZIA 3FFGL 4D0EA 1UZQA 2RHPA 2FLGA 1BF9A 3KQBL 2XC0L 1U8CB 4Y76B 3KQDL 1FE2A 2KB9A 1EMOA 1EPHA 1YUFA 3FBYA 1EBVA 2OYUP 3RR3A 1P0SL 3CA7A 1V3XB 4CUDA 1XKBA 4CSYA 1NFUB 4X8SL 4ZAEB 4RS0A 4Y6DB 2J94B 2GD4A 1KSNB 5KN5C 5L2ZL 1NQLB 3TK5B 1IQFL 4LMFA 5IKTA 1AUTL 1APOA 3SW2A 4RUTA 2BQWA 1PTHA 2K2TA 4D90A 2ADXA 3IJEB 3N8YB 2J38B 3LTFB 1NFXB 1LQDA 2W2OE 1YUGA 1EQGA 1L3YA 5JVYA 3HPTA 1YUKB 2VWMK 4BXSA 1WU1B 1YGCL 4BDWA 2WPHE 5JW1A 1V1IA 2VWLL 1JBUL 1HREA 2VVCK 1FJSL 1EAIC 2HORA 2WPKE 1IQNL 3N8WA 1Z6EL 2BOUA 2VWOL 3OLTA 2WPLE 3KQCL 3ZYGA 3HS5A 3N8XA 1PGEA 2F9BL 5JB9E 1FAXL 2VH6B 4E1GA 1G2LB 1NPEB 4GU4A 2P3FL 3HS6A 4NA9L 1WHFA 1F0SB 2VVVL 1L5GB
chains in the Genus database with same CATH topology
2DDUA 3H5CB 4Y79B 2BMGA 2YGQA 2EI8B 2FD6A 4Z0LA 4BTTA 1UZPA 2BOHA 3Q7DA 1HCGB 3TK6B 3ENSA 1N7DA 4Y7BB 1ADXA 1IGXA 2KL7A 1KLOA 1CCFA 3QH0A 1IOXA 1HX2A 1G1QA 2BQ7A 2J2UB 2XC4L 4Y7AB 4ZXXL 3MDLA 1F7EA 3NTGA 4YT7L 3KRKA 3KL6B 3V64C 1XKAL 4O1ZA 1LMJA 1Q4GA 3GISX 1U67A 2WG4B 3BT1A 1TPGA 4BXWA 1X7AL 4BTUA 1TOZA 1IQKL 1FAKL 4ZHAB 1A3PA 4PH9A 5F19A 2Y7ZB 4JYVL 3NT1A 2MHPA 2KV4A 4X8UL 1J9CL 1G1RA 2TGFA 2J4IB 3HO5A 2J95B 2P3UA 1IQML 1I0UA 1URKA 1GK5A 1K37A 3HS7A 2WYJB 3ELAL 3M37L 4ZH8B 3N8WB 1NT0A 4O02B 4JZEL 1CCVA 1MQ6L 1TLEA 3LC3B 3R05A 1G2MB 4M10A 4TGFA 5I46L 1C5MF 1QFKL 2UWPB 4OTYA 3IITB 1Z6CA 1W8BL 3V65B 4X8VL 3NTBA 1HZ8A 4XBMA 1EPIA 2WYGB 1P9JA 4NG9L 5FDQA 1NFWB 5CKNA 5IKVA 2MGRA 3DEMA 2B7DL 3ASIA 3ZYIB 4G1MB 2FLBL 3KQEL 2VWNL 1IQIL 2Y5GL 2WPME 4D0FA 1IJQA 3ZYJB 5IKQA 2UWOB 1O5DL 1IQLL 3C9AC 3M36L 1DX5I 2XBXL 1CVUA 2M74A 2NPRA 1IQHL 4JYUL 6COXA 2P3TA 5KIRA 1G1SA 4LORA 2W3KB 1IP0A 1PRHA 3NJPC 5E8DA 2P95L 5IKRA 5L30L 2MGPA 1NFYB 5CISA 3FCSB 4M11A 3HO4A 3U73A 1ATDA 5JBBE 1APQA 5JBAE 4X8TL 4RRXA 1K36A 2VVUL 2XBVL 1DIYA 3LIWB 2W86A 1HT8A 1XFEA 1JV2B 1CVWL 2P94L 3LN0A 3PGHA 3LC5B 4ISHL 2W2QE 2H9EL 1LPZA 2D1JB 1ZAQA 2W2ME 4JZFL 3K9XA 2PHBB 3KK6A 1HAFA 3U7UG 2WFTA 4NGAL 4Z6AL 3F1SB 4FM5A 2WZPP 4ISIL 2W2PE 4BDXA 4C16A 5CKMA 5JVZA 4OTJA 2EI7B 2VH0B 4XL1A 2Y5FL 1NZIA 1EZQB 2WG3C 2WPIE 4MMZB 5CKQA 1CX2A 4A7IA 1SZBA 1EMNA 1M1XB 2Y80B 1FF7A 2I9BA 2P28B 3SOVA 2CJIB 2EI6B 3CS7L 4CUEA 2Y7XB 5COXA 1YO8A 1CEJA 2UWLB 3BT2A 3KCGL 2PR3B 3QCWA 2I9AA 3SOBB 2FLRL 2YGPA 5L2YL 4YZUB 4A94C 4COXA 4JZDL 2H9EC 2OYEP 2XBWL 4MMYB 1MQ5L 2BQ6A 2P16L 1LPGA 1XDTR 3TH3L 1ATBA 2P3FN 2Y5HL 1G1TA 3MQEA 2RNLA 2XBYL 2BZ6L 2RA0L 3Q3KB 2PUQL 2VJ3A 1WHEA 1MOXC 2Y38A 4YT6L 3POYA 5K0HB 1HRFA 3HO3A 2WPJE 3N8ZA 1UZJA 2P93L 1COUA 1EQHA 3QMOA 4ZXYL 1LMMA 2G00L 3F6UL 4XLWA 4Y71B 3TBDA 3LTGD 1CQEA 2P26A 3S6XA 1IQEL 1JL9A 2W2NE 2J34B 1LPKA 1OB1C 3BPSE 3CFWA 2W26B 2K2SB 2BOKL 2BOXA 1DDXA 3N8YA 1PFXL 5JBCE 1FFMA 1EGFA 1IGZA 1KLIL 1IQJL 4AQTA 4RRYA 1ATAA 3OLUA 2WFXB 2W3IB 5EGMB 1IQGL 1HT5A 1KLJL 1B9WA 2YGOA 1EPGA 1DQBA 3SOQA 2Y81B 1DVAL 2Q1JB 4RRWA 2BO2A 2XC5L 3LAQA 3TGFA 1PXXA 1ATEA 4RRZA 1RFNB 1IOEL 1EPJA 1W7XL 2AYLA 3CENL 3GCXE 1HJ7A 2JKHL 1F7MA 2FZZL 3EGFA 1UZKA 2KNIA 4MMXB 4CUFA 2Y82B 3P5BL 3GCWE 1F0RB 3N8VA 4BTIA 5F1AA 1FSBA 1IVOC 3LN1A 1HAEA 1KIGL 5JB8E 1N1IA 4Z0KB 3TZIA 3FFGL 4D0EA 1UZQA 2RHPA 2FLGA 1BF9A 3KQBL 2XC0L 1U8CB 4Y76B 3KQDL 1FE2A 2KB9A 1EMOA 1EPHA 1YUFA 3FBYA 1EBVA 2OYUP 3RR3A 1P0SL 3CA7A 1V3XB 4CUDA 1XKBA 4CSYA 1NFUB 4X8SL 4ZAEB 4RS0A 4Y6DB 2J94B 2GD4A 1KSNB 5KN5C 5L2ZL 1NQLB 3TK5B 1IQFL 4LMFA 5IKTA 1AUTL 1APOA 3SW2A 4RUTA 2BQWA 1PTHA 2K2TA 4D90A 2ADXA 3IJEB 3N8YB 2J38B 3LTFB 1NFXB 1LQDA 2W2OE 1YUGA 1EQGA 1L3YA 5JVYA 3HPTA 1YUKB 2VWMK 4BXSA 1WU1B 1YGCL 4BDWA 2WPHE 5JW1A 2VWLL 1JBUL 1HREA 2VVCK 1FJSL 1EAIC 2WPKE 1IQNL 3N8WA 1Z6EL 2BOUA 2VWOL 3OLTA 2WPLE 3KQCL 3ZYGA 3HS5A 3N8XA 1PGEA 2F9BL 5JB9E 1FAXL 2VH6B 4E1GA 1G2LB 1NPEB 2P3FL 3HS6A 4NA9L 1WHFA 1F0SB 2VVVL 1L5GB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DDU A;  3H5C B;  4Y79 B;  2BMG A;  2EI8 B;  2FD6 A;  4Z0L A;  4BTT A;  1UZP A;  2BOH A;  3Q7D A;  1HCG B;  3TK6 B;  3ENS A;  1N7D A;  4Y7B B;  1ADX A;  1IGX A;  2KL7 A;  1KLO A;  1CCF A;  3QH0 A;  1IOX A;  1HX2 A;  1G1Q A;  2BQ7 A;  2J2U B;  2XC4 L;  4Y7A B;  4ZXX L;  3MDL A;  1F7E A;  3NTG A;  4YT7 L;  3KRK A;  3KL6 B;  3V64 C;  1XKA L;  4O1Z A;  1LMJ A;  1Q4G A;  3GIS X;  1U67 A;  2WG4 B;  3BT1 A;  1TPG A;  4BXW A;  1X7A L;  4BTU A;  1TOZ A;  1IQK L;  1FAK L;  4ZHA B;  1A3P A;  4PH9 A;  5F19 A;  2Y7Z B;  4JYV L;  3NT1 A;  2MHP A;  2KV4 A;  4X8U L;  1J9C L;  1G1R A;  2TGF A;  2J4I B;  3HO5 A;  2J95 B;  2P3U A;  1IQM L;  1I0U A;  1URK A;  1GK5 A;  1K37 A;  3HS7 A;  2WYJ B;  3ELA L;  3M37 L;  4ZH8 B;  3N8W B;  1NT0 A;  4O02 B;  4JZE L;  1CCV A;  1MQ6 L;  1TLE A;  3LC3 B;  3R05 A;  1G2M B;  4M10 A;  4TGF A;  5I46 L;  1C5M F;  1QFK L;  2UWP B;  4OTY A;  3IIT B;  1Z6C A;  1W8B L;  3V65 B;  4X8V L;  3NTB A;  1HZ8 A;  4XBM A;  1EPI A;  2WYG B;  1P9J A;  4NG9 L;  5FDQ A;  1NFW B;  5CKN A;  5IKV A;  2MGR A;  3DEM A;  2B7D L;  3ASI A;  3ZYI B;  4G1M B;  2FLB L;  3KQE L;  2VWN L;  1IQI L;  2Y5G L;  2WPM E;  4D0F A;  1IJQ A;  3ZYJ B;  5IKQ A;  2UWO B;  1O5D L;  1IQL L;  3C9A C;  3M36 L;  1DX5 I;  2XBX L;  1CVU A;  2M74 A;  2NPR A;  1IQH L;  4JYU L;  6COX A;  2P3T A;  5KIR A;  1G1S A;  4LOR A;  2W3K B;  1IP0 A;  1PRH A;  3NJP C;  5E8D A;  2P95 L;  5IKR A;  5L30 L;  2MGP A;  1NFY B;  5CIS A;  3FCS B;  4M11 A;  3HO4 A;  3U73 A;  1ATD A;  5JBB E;  1APQ A;  5JBA E;  4X8T L;  4RRX A;  1K36 A;  2VVU L;  2XBV L;  1DIY A;  3LIW B;  2W86 A;  1HT8 A;  1XFE A;  1JV2 B;  1CVW L;  2P94 L;  3LN0 A;  3PGH A;  3LC5 B;  4ISH L;  2W2Q E;  2H9E L;  1LPZ A;  2D1J B;  1ZAQ A;  2W2M E;  4JZF L;  3K9X A;  2PHB B;  3KK6 A;  1HAF A;  3U7U G;  2WFT A;  4NGA L;  4Z6A L;  3F1S B;  4FM5 A;  4ISI L;  2W2P E;  4BDX A;  4C16 A;  5CKM A;  5JVZ A;  4OTJ A;  2EI7 B;  2VH0 B;  4XL1 A;  2Y5F L;  1NZI A;  1EZQ B;  2WG3 C;  2WPI E;  4MMZ B;  5CKQ A;  1CX2 A;  4A7I A;  1SZB A;  1EMN A;  1M1X B;  2Y80 B;  1FF7 A;  2I9B A;  2P28 B;  3SOV A;  2CJI B;  2EI6 B;  3CS7 L;  4CUE A;  2Y7X B;  5COX A;  1YO8 A;  1CEJ A;  2UWL B;  3BT2 A;  3KCG L;  2PR3 B;  3QCW A;  2I9A A;  3SOB B;  2FLR L;  2YGP A;  5L2Y L;  4YZU B;  4COX A;  4JZD L;  2OYE P;  2XBW L;  4MMY B;  1MQ5 L;  2BQ6 A;  2P16 L;  1LPG A;  1XDT R;  3TH3 L;  1ATB A;  2P3F N;  2Y5H L;  1G1T A;  3MQE A;  2RNL A;  2XBY L;  2BZ6 L;  2RA0 L;  3Q3K B;  2PUQ L;  2VJ3 A;  1WHE A;  1MOX C;  2Y38 A;  4YT6 L;  3POY A;  5K0H B;  1HRF A;  3HO3 A;  2WPJ E;  3N8Z A;  1UZJ A;  2P93 L;  1COU A;  1EQH A;  3QMO A;  4ZXY L;  2G00 L;  3F6U L;  4XLW A;  4Y71 B;  3TBD A;  3LTG D;  1CQE A;  2P26 A;  1IQE L;  1JL9 A;  2W2N E;  2J34 B;  1LPK A;  1OB1 C;  3BPS E;  3CFW A;  2W26 B;  2K2S B;  2BOK L;  2BOX A;  1DDX A;  3N8Y A;  1PFX L;  5JBC E;  1FFM A;  1EGF A;  1IGZ A;  1KLI L;  1IQJ L;  4AQT A;  4RRY A;  1ATA A;  3OLU A;  2WFX B;  2W3I B;  5EGM B;  1IQG L;  1HT5 A;  1KLJ L;  1B9W A;  2YGO A;  1EPG A;  1DQB A;  3SOQ A;  2Y81 B;  1DVA L;  2Q1J B;  4RRW A;  2BO2 A;  2XC5 L;  3LAQ A;  3TGF A;  1PXX A;  1ATE A;  4RRZ A;  1RFN B;  1IOE L;  1EPJ A;  1W7X L;  2AYL A;  3CEN L;  3GCX E;  1HJ7 A;  2JKH L;  1F7M A;  2FZZ L;  3EGF A;  1UZK A;  4MMX B;  4CUF A;  2Y82 B;  3P5B L;  3GCW E;  1F0R B;  3N8V A;  4BTI A;  5F1A A;  1FSB A;  1IVO C;  3LN1 A;  1HAE A;  1KIG L;  5JB8 E;  1N1I A;  4Z0K B;  3TZI A;  3FFG L;  4D0E A;  1UZQ A;  2RHP A;  2FLG A;  1BF9 A;  3KQB L;  2XC0 L;  1U8C B;  4Y76 B;  3KQD L;  1FE2 A;  2KB9 A;  1EMO A;  1EPH A;  1YUF A;  3FBY A;  1EBV A;  2OYU P;  3RR3 A;  1P0S L;  3CA7 A;  1V3X B;  4CUD A;  1XKB A;  4CSY A;  1NFU B;  4X8S L;  4ZAE B;  4RS0 A;  4Y6D B;  2J94 B;  2GD4 A;  1KSN B;  5KN5 C;  5L2Z L;  1NQL B;  3TK5 B;  1IQF L;  4LMF A;  5IKT A;  1AUT L;  1APO A;  3SW2 A;  4RUT A;  2BQW A;  1PTH A;  2K2T A;  4D90 A;  2ADX A;  3IJE B;  3N8Y B;  2J38 B;  3LTF B;  1NFX B;  1LQD A;  2W2O E;  1YUG A;  1EQG A;  1L3Y A;  5JVY A;  3HPT A;  1YUK B;  2VWM K;  4BXS A;  1WU1 B;  1YGC L;  4BDW A;  2WPH E;  5JW1 A;  2VWL L;  1JBU L;  1HRE A;  2VVC K;  1FJS L;  1EAI C;  2WPK E;  1IQN L;  3N8W A;  1Z6E L;  2BOU A;  2VWO L;  3OLT A;  2WPL E;  3KQC L;  3ZYG A;  3HS5 A;  3N8X A;  1PGE A;  2F9B L;  5JB9 E;  1FAX L;  2VH6 B;  4E1G A;  1G2L B;  1NPE B;  2P3F L;  3HS6 A;  4NA9 L;  1WHF A;  1F0S B;  2VVV L;  1L5G B; 
#chains in the Genus database with same CATH topology
 2DDU A;  3H5C B;  4Y79 B;  2BMG A;  2YGQ A;  2EI8 B;  2FD6 A;  4Z0L A;  4BTT A;  1UZP A;  2BOH A;  3Q7D A;  1HCG B;  3TK6 B;  3ENS A;  1N7D A;  4Y7B B;  1ADX A;  1IGX A;  2KL7 A;  1KLO A;  1CCF A;  3QH0 A;  1IOX A;  1HX2 A;  1G1Q A;  2BQ7 A;  2J2U B;  2XC4 L;  4Y7A B;  4ZXX L;  3MDL A;  1F7E A;  3NTG A;  4YT7 L;  3KRK A;  3KL6 B;  3V64 C;  1XKA L;  4O1Z A;  1LMJ A;  1Q4G A;  3GIS X;  1U67 A;  2WG4 B;  3BT1 A;  1TPG A;  4BXW A;  1X7A L;  4BTU A;  1TOZ A;  1IQK L;  1FAK L;  4ZHA B;  1A3P A;  4PH9 A;  5F19 A;  2Y7Z B;  4JYV L;  3NT1 A;  2MHP A;  2KV4 A;  4X8U L;  1J9C L;  1G1R A;  2TGF A;  2J4I B;  3HO5 A;  2J95 B;  2P3U A;  1IQM L;  1I0U A;  1URK A;  1GK5 A;  1K37 A;  3HS7 A;  2WYJ B;  3ELA L;  3M37 L;  4ZH8 B;  3N8W B;  1NT0 A;  4O02 B;  4JZE L;  1CCV A;  1MQ6 L;  1TLE A;  3LC3 B;  2BT8 A;  3R05 A;  1G2M B;  4M10 A;  4TGF A;  5I46 L;  1C5M F;  1QFK L;  2UWP B;  4OTY A;  3IIT B;  1Z6C A;  1W8B L;  3V65 B;  4X8V L;  3NTB A;  1HZ8 A;  4XBM A;  1EPI A;  2WYG B;  1P9J A;  4NG9 L;  5FDQ A;  1NFW B;  5CKN A;  5IKV A;  2MGR A;  3DEM A;  2B7D L;  3ASI A;  3ZYI B;  4G1M B;  2FLB L;  3KQE L;  2VWN L;  1IQI L;  2Y5G L;  2WPM E;  4D0F A;  1IJQ A;  3ZYJ B;  5IKQ A;  2UWO B;  1O5D L;  1IQL L;  3C9A C;  3M36 L;  1DX5 I;  2XBX L;  1CVU A;  2M74 A;  2NPR A;  1IQH L;  4JYU L;  6COX A;  2P3T A;  5KIR A;  1G1S A;  4LOR A;  2W3K B;  1IP0 A;  1PRH A;  3NJP C;  5E8D A;  2P95 L;  5IKR A;  5L30 L;  2MGP A;  1NFY B;  5CIS A;  3FCS B;  4M11 A;  3HO4 A;  3U73 A;  1ATD A;  5JBB E;  1APQ A;  5JBA E;  4X8T L;  4RRX A;  1K36 A;  2VVU L;  2XBV L;  1DIY A;  3LIW B;  2W86 A;  1HT8 A;  1XFE A;  1JV2 B;  1CVW L;  2P94 L;  3LN0 A;  3PGH A;  3LC5 B;  4ISH L;  2W2Q E;  2H9E L;  1LPZ A;  2D1J B;  1ZAQ A;  2W2M E;  4JZF L;  3K9X A;  2PHB B;  2HOX A;  3KK6 A;  1HAF A;  3U7U G;  2WFT A;  4NGA L;  4Z6A L;  3F1S B;  4FM5 A;  2WZP P;  4ISI L;  2W2P E;  4BDX A;  4C16 A;  5CKM A;  5JVZ A;  4OTJ A;  2EI7 B;  1QIU A;  2VH0 B;  4XL1 A;  2Y5F L;  1NZI A;  1EZQ B;  2WG3 C;  2WPI E;  4MMZ B;  5CKQ A;  1CX2 A;  4A7I A;  1SZB A;  1EMN A;  1M1X B;  2Y80 B;  1FF7 A;  2I9B A;  2P28 B;  3SOV A;  2CJI B;  2EI6 B;  3CS7 L;  4CUE A;  2Y7X B;  5COX A;  1YO8 A;  1CEJ A;  2UWL B;  1LK9 A;  3BT2 A;  3KCG L;  2PR3 B;  3QCW A;  2I9A A;  3SOB B;  2BT7 A;  2FLR L;  2YGP A;  5L2Y L;  4YZU B;  4A94 C;  4COX A;  4JZD L;  2H9E C;  2OYE P;  2XBW L;  4MMY B;  1MQ5 L;  2BQ6 A;  2P16 L;  1LPG A;  1XDT R;  3TH3 L;  1ATB A;  2P3F N;  2Y5H L;  1G1T A;  4GU3 A;  3MQE A;  2RNL A;  2XBY L;  2BZ6 L;  2RA0 L;  2BSF A;  3Q3K B;  2PUQ L;  2VJ3 A;  1WHE A;  2VRS A;  1MOX C;  2Y38 A;  4YT6 L;  3POY A;  5K0H B;  1HRF A;  3HO3 A;  2WPJ E;  3N8Z A;  1UZJ A;  2P93 L;  1COU A;  1EQH A;  3QMO A;  4ZXY L;  1LMM A;  2G00 L;  3F6U L;  4XLW A;  4Y71 B;  3TBD A;  3LTG D;  1CQE A;  2P26 A;  3S6X A;  1IQE L;  1JL9 A;  2W2N E;  2J34 B;  1LPK A;  2JJL A;  1OB1 C;  3BPS E;  3CFW A;  2W26 B;  2K2S B;  2BOK L;  2BOX A;  1DDX A;  3N8Y A;  1PFX L;  5JBC E;  1FFM A;  1EGF A;  1IGZ A;  1KLI L;  1IQJ L;  4AQT A;  1V1H A;  4RRY A;  1ATA A;  3OLU A;  2WFX B;  2W3I B;  5EGM B;  1IQG L;  1HT5 A;  1KLJ L;  1B9W A;  2YGO A;  1EPG A;  1DQB A;  3SOQ A;  2Y81 B;  1DVA L;  2Q1J B;  4RRW A;  2BO2 A;  2XC5 L;  3LAQ A;  3TGF A;  1PXX A;  1ATE A;  4RRZ A;  1RFN B;  1IOE L;  1EPJ A;  1W7X L;  2AYL A;  3CEN L;  3GCX E;  1HJ7 A;  2JKH L;  1F7M A;  2FZZ L;  3EGF A;  1UZK A;  2KNI A;  4MMX B;  4CUF A;  2Y82 B;  3P5B L;  3GCW E;  1F0R B;  3N8V A;  4BTI A;  5F1A A;  1FSB A;  1IVO C;  3LN1 A;  1HAE A;  1KIG L;  5JB8 E;  1N1I A;  1KKE A;  4Z0K B;  3TZI A;  3FFG L;  4D0E A;  1UZQ A;  2RHP A;  2FLG A;  1BF9 A;  3KQB L;  2XC0 L;  1U8C B;  4Y76 B;  3KQD L;  1FE2 A;  2KB9 A;  1EMO A;  1EPH A;  1YUF A;  3FBY A;  1EBV A;  2OYU P;  3RR3 A;  1P0S L;  3CA7 A;  1V3X B;  4CUD A;  1XKB A;  4CSY A;  1NFU B;  4X8S L;  4ZAE B;  4RS0 A;  4Y6D B;  2J94 B;  2GD4 A;  1KSN B;  5KN5 C;  5L2Z L;  1NQL B;  3TK5 B;  1IQF L;  4LMF A;  5IKT A;  1AUT L;  1APO A;  3SW2 A;  4RUT A;  2BQW A;  1PTH A;  2K2T A;  4D90 A;  2ADX A;  3IJE B;  3N8Y B;  2J38 B;  3LTF B;  1NFX B;  1LQD A;  2W2O E;  1YUG A;  1EQG A;  1L3Y A;  5JVY A;  3HPT A;  1YUK B;  2VWM K;  4BXS A;  1WU1 B;  1YGC L;  4BDW A;  2WPH E;  5JW1 A;  1V1I A;  2VWL L;  1JBU L;  1HRE A;  2VVC K;  1FJS L;  1EAI C;  2HOR A;  2WPK E;  1IQN L;  3N8W A;  1Z6E L;  2BOU A;  2VWO L;  3OLT A;  2WPL E;  3KQC L;  3ZYG A;  3HS5 A;  3N8X A;  1PGE A;  2F9B L;  5JB9 E;  1FAX L;  2VH6 B;  4E1G A;  1G2L B;  1NPE B;  4GU4 A;  2P3F L;  3HS6 A;  4NA9 L;  1WHF A;  1F0S B;  2VVV L;  1L5G B; 
#chains in the Genus database with same CATH homology
 2DDU A;  3H5C B;  4Y79 B;  2BMG A;  2YGQ A;  2EI8 B;  2FD6 A;  4Z0L A;  4BTT A;  1UZP A;  2BOH A;  3Q7D A;  1HCG B;  3TK6 B;  3ENS A;  1N7D A;  4Y7B B;  1ADX A;  1IGX A;  2KL7 A;  1KLO A;  1CCF A;  3QH0 A;  1IOX A;  1HX2 A;  1G1Q A;  2BQ7 A;  2J2U B;  2XC4 L;  4Y7A B;  4ZXX L;  3MDL A;  1F7E A;  3NTG A;  4YT7 L;  3KRK A;  3KL6 B;  3V64 C;  1XKA L;  4O1Z A;  1LMJ A;  1Q4G A;  3GIS X;  1U67 A;  2WG4 B;  3BT1 A;  1TPG A;  4BXW A;  1X7A L;  4BTU A;  1TOZ A;  1IQK L;  1FAK L;  4ZHA B;  1A3P A;  4PH9 A;  5F19 A;  2Y7Z B;  4JYV L;  3NT1 A;  2MHP A;  2KV4 A;  4X8U L;  1J9C L;  1G1R A;  2TGF A;  2J4I B;  3HO5 A;  2J95 B;  2P3U A;  1IQM L;  1I0U A;  1URK A;  1GK5 A;  1K37 A;  3HS7 A;  2WYJ B;  3ELA L;  3M37 L;  4ZH8 B;  3N8W B;  1NT0 A;  4O02 B;  4JZE L;  1CCV A;  1MQ6 L;  1TLE A;  3LC3 B;  3R05 A;  1G2M B;  4M10 A;  4TGF A;  5I46 L;  1C5M F;  1QFK L;  2UWP B;  4OTY A;  3IIT B;  1Z6C A;  1W8B L;  3V65 B;  4X8V L;  3NTB A;  1HZ8 A;  4XBM A;  1EPI A;  2WYG B;  1P9J A;  4NG9 L;  5FDQ A;  1NFW B;  5CKN A;  5IKV A;  2MGR A;  3DEM A;  2B7D L;  3ASI A;  3ZYI B;  4G1M B;  2FLB L;  3KQE L;  2VWN L;  1IQI L;  2Y5G L;  2WPM E;  4D0F A;  1IJQ A;  3ZYJ B;  5IKQ A;  2UWO B;  1O5D L;  1IQL L;  3C9A C;  3M36 L;  1DX5 I;  2XBX L;  1CVU A;  2M74 A;  2NPR A;  1IQH L;  4JYU L;  6COX A;  2P3T A;  5KIR A;  1G1S A;  4LOR A;  2W3K B;  1IP0 A;  1PRH A;  3NJP C;  5E8D A;  2P95 L;  5IKR A;  5L30 L;  2MGP A;  1NFY B;  5CIS A;  3FCS B;  4M11 A;  3HO4 A;  3U73 A;  1ATD A;  5JBB E;  1APQ A;  5JBA E;  4X8T L;  4RRX A;  1K36 A;  2VVU L;  2XBV L;  1DIY A;  3LIW B;  2W86 A;  1HT8 A;  1XFE A;  1JV2 B;  1CVW L;  2P94 L;  3LN0 A;  3PGH A;  3LC5 B;  4ISH L;  2W2Q E;  2H9E L;  1LPZ A;  2D1J B;  1ZAQ A;  2W2M E;  4JZF L;  3K9X A;  2PHB B;  3KK6 A;  1HAF A;  3U7U G;  2WFT A;  4NGA L;  4Z6A L;  3F1S B;  4FM5 A;  2WZP P;  4ISI L;  2W2P E;  4BDX A;  4C16 A;  5CKM A;  5JVZ A;  4OTJ A;  2EI7 B;  2VH0 B;  4XL1 A;  2Y5F L;  1NZI A;  1EZQ B;  2WG3 C;  2WPI E;  4MMZ B;  5CKQ A;  1CX2 A;  4A7I A;  1SZB A;  1EMN A;  1M1X B;  2Y80 B;  1FF7 A;  2I9B A;  2P28 B;  3SOV A;  2CJI B;  2EI6 B;  3CS7 L;  4CUE A;  2Y7X B;  5COX A;  1YO8 A;  1CEJ A;  2UWL B;  3BT2 A;  3KCG L;  2PR3 B;  3QCW A;  2I9A A;  3SOB B;  2FLR L;  2YGP A;  5L2Y L;  4YZU B;  4A94 C;  4COX A;  4JZD L;  2H9E C;  2OYE P;  2XBW L;  4MMY B;  1MQ5 L;  2BQ6 A;  2P16 L;  1LPG A;  1XDT R;  3TH3 L;  1ATB A;  2P3F N;  2Y5H L;  1G1T A;  3MQE A;  2RNL A;  2XBY L;  2BZ6 L;  2RA0 L;  3Q3K B;  2PUQ L;  2VJ3 A;  1WHE A;  1MOX C;  2Y38 A;  4YT6 L;  3POY A;  5K0H B;  1HRF A;  3HO3 A;  2WPJ E;  3N8Z A;  1UZJ A;  2P93 L;  1COU A;  1EQH A;  3QMO A;  4ZXY L;  1LMM A;  2G00 L;  3F6U L;  4XLW A;  4Y71 B;  3TBD A;  3LTG D;  1CQE A;  2P26 A;  3S6X A;  1IQE L;  1JL9 A;  2W2N E;  2J34 B;  1LPK A;  1OB1 C;  3BPS E;  3CFW A;  2W26 B;  2K2S B;  2BOK L;  2BOX A;  1DDX A;  3N8Y A;  1PFX L;  5JBC E;  1FFM A;  1EGF A;  1IGZ A;  1KLI L;  1IQJ L;  4AQT A;  4RRY A;  1ATA A;  3OLU A;  2WFX B;  2W3I B;  5EGM B;  1IQG L;  1HT5 A;  1KLJ L;  1B9W A;  2YGO A;  1EPG A;  1DQB A;  3SOQ A;  2Y81 B;  1DVA L;  2Q1J B;  4RRW A;  2BO2 A;  2XC5 L;  3LAQ A;  3TGF A;  1PXX A;  1ATE A;  4RRZ A;  1RFN B;  1IOE L;  1EPJ A;  1W7X L;  2AYL A;  3CEN L;  3GCX E;  1HJ7 A;  2JKH L;  1F7M A;  2FZZ L;  3EGF A;  1UZK A;  2KNI A;  4MMX B;  4CUF A;  2Y82 B;  3P5B L;  3GCW E;  1F0R B;  3N8V A;  4BTI A;  5F1A A;  1FSB A;  1IVO C;  3LN1 A;  1HAE A;  1KIG L;  5JB8 E;  1N1I A;  4Z0K B;  3TZI A;  3FFG L;  4D0E A;  1UZQ A;  2RHP A;  2FLG A;  1BF9 A;  3KQB L;  2XC0 L;  1U8C B;  4Y76 B;  3KQD L;  1FE2 A;  2KB9 A;  1EMO A;  1EPH A;  1YUF A;  3FBY A;  1EBV A;  2OYU P;  3RR3 A;  1P0S L;  3CA7 A;  1V3X B;  4CUD A;  1XKB A;  4CSY A;  1NFU B;  4X8S L;  4ZAE B;  4RS0 A;  4Y6D B;  2J94 B;  2GD4 A;  1KSN B;  5KN5 C;  5L2Z L;  1NQL B;  3TK5 B;  1IQF L;  4LMF A;  5IKT A;  1AUT L;  1APO A;  3SW2 A;  4RUT A;  2BQW A;  1PTH A;  2K2T A;  4D90 A;  2ADX A;  3IJE B;  3N8Y B;  2J38 B;  3LTF B;  1NFX B;  1LQD A;  2W2O E;  1YUG A;  1EQG A;  1L3Y A;  5JVY A;  3HPT A;  1YUK B;  2VWM K;  4BXS A;  1WU1 B;  1YGC L;  4BDW A;  2WPH E;  5JW1 A;  2VWL L;  1JBU L;  1HRE A;  2VVC K;  1FJS L;  1EAI C;  2WPK E;  1IQN L;  3N8W A;  1Z6E L;  2BOU A;  2VWO L;  3OLT A;  2WPL E;  3KQC L;  3ZYG A;  3HS5 A;  3N8X A;  1PGE A;  2F9B L;  5JB9 E;  1FAX L;  2VH6 B;  4E1G A;  1G2L B;  1NPE B;  2P3F L;  3HS6 A;  4NA9 L;  1WHF A;  1F0S B;  2VVV L;  1L5G B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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