2FZZL

Factor xa in complex with the inhibitor 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(2'-(((3r)-3-hydroxy-1-pyrrolidinyl)methyl)-4-biphenylyl)-3-(trifluoromethyl)-1,4,5,6-tetrahydro-7h-pyrazolo[3,4-c]pyridin-7-one
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
publication title 1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.
pubmed doi rcsb
molecule keywords Coagulation factor X
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2006-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2fzzL00
2EI6B 3OLTA 3BPSE 1EQHA 3POYA 4ISIL 3LC3B 4MMYB 4Z0LA 1IQNL 4RRWA 1XKBA 3N8VA 3F6UL 1NZIA 2WPIE 2P95L 2P94L 3KCGL 3K9XA 3SOVA 4PH9A 1EPJA 1I0UA 2KV4A 3LTFB 1JL9A 2W3KB 2Y80B 2YGOA 4Y79B 4D0FA 4YT7L 2J38B 2FLGA 3KK6A 4BTUA 3GCWE 1UZPA 2CJIB 4OTJA 4COXA 1NFUB 1N7DA 4JZDL 2RHPA 3U7UG 5EGMB 2VWLL 5FDQA 1U8CB 1U67A 2ADXA 2J94B 1IOEL 3LIWB 5JBCE 4C16A 2J4IB 2XBYL 3R05A 5IKQA 3NJPC 1PGEA 3NT1A 2W2NE 4BXWA 1XDTR 3Q3KB 4LORA 1KLOA 2Y38A 1DQBA 3V65B 1YUGA 3QMOA 2OYEP 1G1QA 5CKNA 2XC0L 5JVZA 2EI8B 1URKA 1HRFA 1RFNB 2BOHA 5CISA 2VH6B 4X8VL 1LPKA 4BTIA 2BZ6L 2J95B 3TH3L 3NTGA 3TZIA 5COXA 2P3FL 4X8SL 2BQ7A 2W3IB 1PXXA 3CA7A 3CENL 1ATDA 2B7DL 1G2LB 2P93L 4MMZB 4Z0KB 5JW1A 2Y82B 3F1SB 4RUTA 4OTYA 1EPIA 1IQJL 1Z6EL 2AYLA 3ZYGA 3ZYJB 1F0SB 2FLRL 3Q7DA 1FAXL 4CSYA 3HS7A 1N1IA 1NQLB 1OB1C 2VVUL 1Q4GA 2WYJB 3LTGD 3N8WA 1YO8A 3LAQA 3TK5B 1TOZA 5JBAE 1MQ6L 2UWLB 5I46L 1UZKA 1IQLL 1WHFA 5L2ZL 3TK6B 5CKMA 1HAFA 5JB9E 1DDXA 3PGHA 3M37L 3KQEL 5F19A 4ZXYL 4A7IA 4NA9L 4O02B 1EMOA 2WG4B 2XBWL 3ELAL 3MDLA 4ZAEB 3TBDA 2WFTA 3QCWA 1P9JA 1F7MA 2XBVL 4X8UL 3GCXE 4Y7AB 1C5MF 3FCSB 2NPRA 2P3TA 1NFYB 3LN1A 2Y81B 1COUA 4BDWA 4YZUB 1CQEA 1UZJA 2BOXA 1Z6CA 4BTTA 4RRXA 1DVAL 1K36A 3LC5B 1HX2A 1CVWL 1KLJL 4XLWA 2W86A 2MGRA 3MQEA 2FLBL 1EPHA 1APQA 1EBVA 1A3PA 2OYUP 3BT2A 4Y76B 1KSNB 1IQIL 1F0RB 1IQGL 2P26A 2VJ3A 5CKQA 1ADXA 3ZYIB 1HJ7A 2UWOB 1V3XB 2VVVL 3N8XA 2W2PE 2D1JB 1SZBA 2JKHL 5K0HB 1CVUA 5JVYA 2WPHE 2PHBB 1FSBA 4JZEL 1L3YA 3KL6B 1G1SA 2BOKL 2DDUA 4JYVL 1EMNA 1K37A 1IGXA 1GK5A 2H9EL 4BXSA 3CS7L 1ATEA 4NGAL 1MOXC 1HCGB 2VWNL 3HO3A 2KB9A 1EPGA 2Y7ZB 2VH0B 4X8TL 1J9CL 2I9BA 4XBMA 4M10A 2BQ6A 1HT8A 1EAIC 2F9BL 4RS0A 3OLUA 2WPME 1FFMA 1IQEL 1ZAQA 3M36L 2RNLA 5L30L 1W7XL 1IQKL 1CCVA 1WU1B 3N8YB 4Z6AL 4CUFA 1YGCL 1FF7A 4O1ZA 1XKAL 4TGFA 2Y7XB 3FBYA 2WYGB 3IITB 1CEJA 3DEMA 1NT0A 2XC5L 1FE2A 3HO4A 2YGPA 1EQGA 2BO2A 1LPGA 4XL1A 3N8ZA 2P3UA 4CUEA 1P0SL 3U73A 2GD4A 2PUQL 2M74A 2W2OE 3HS6A 1NFWB 2Y5FL 3HO5A 5JBBE 4ISHL 3N8YA 1MQ5L 1IVOC 1BF9A 2VVCK 4RRYA 3KQDL 2Y5GL 3LN0A 4Y71B 2Q1JB 1G1TA 1G1RA 2UWPB 2W2QE 4LMFA 5F1AA 3ASIA 1EZQB 1IOXA 2MHPA 2J34B 2VWMK 4ZH8B 4AQTA 2W2ME 2I9AA 3FFGL 1KLIL 1LPZA 3ENSA 2P16L 5JB8E 3HPTA 2WFXB 3SOBB 1DX5I 1JBUL 2K2SB 3SW2A 1KIGL 2BQWA 4ZHAB 1IGZA 3IJEB 3KQCL 3P5BL 5E8DA 5IKTA 2BMGA 2W26B 3H5CB 1IJQA 2WPKE 3V64C 3HS5A 4D0EA 2MGPA 1IQFL 1IP0A 1NPEB 2WPLE 6COXA 4JZFL 4MMXB 3RR3A 1HZ8A 1TPGA 3C9AC 4ZXXL 5IKRA 1DIYA 1YUKB 4G1MB 2P3FN 4CUDA 4E1GA 1B9WA 2FZZL 1ATAA 1ATBA 1IQHL 1WHEA 3KQBL 2P28B 1CX2A 2WPJE 4FM5A 4YT6L 5L2YL 3CFWA 3SOQA 1O5DL 3KRKA 2J2UB 2K2TA 3EGFA 2VWOL 2Y5HL 4NG9L 1CCFA 2XBXL 1UZQA 1HAEA 4BDXA 1APOA 1HT5A 3TGFA 3QH0A 1F7EA 5KIRA 2WG3C 1NFXB 1TLEA 3N8WB 1AUTL 4Y6DB 1XFEA 1X7AL 3BT1A 1HREA 5IKVA 1IQML 4Y7BB 4JYUL 1JV2B 2XC4L 2BOUA 1EGFA 1QFKL 1W8BL 2EI7B 3NTBA 1PRHA 1FAKL 1PTHA 3GISX 1LQDA 2KL7A 2PR3B 1M1XB 1LMJA 1YUFA 2G00L 1FJSL 1L5GB 4RRZA 2FD6A 1PFXL 2RA0L 1G2MB 4M11A 5KN5C 2TGFA 4D90A
chains in the Genus database with same CATH superfamily
2EI6B 3OLTA 3BPSE 1EQHA 3POYA 4ISIL 3LC3B 4MMYB 4Z0LA 1IQNL 4RRWA 1XKBA 3N8VA 3F6UL 1NZIA 2WPIE 2P95L 2P94L 3KCGL 3K9XA 3SOVA 4PH9A 1EPJA 1I0UA 2KV4A 3LTFB 1JL9A 2W3KB 2Y80B 2YGOA 4Y79B 4D0FA 4YT7L 2J38B 1V1HA 2FLGA 3KK6A 4GU3A 4BTUA 3GCWE 1UZPA 2CJIB 4OTJA 4COXA 2BT8A 1NFUB 1N7DA 4JZDL 2RHPA 3U7UG 5EGMB 2VWLL 5FDQA 1U8CB 1U67A 2WZPP 2ADXA 2J94B 1IOEL 3LIWB 5JBCE 4C16A 2J4IB 2XBYL 3R05A 1LMMA 5IKQA 3NJPC 1PGEA 3NT1A 2W2NE 4BXWA 1XDTR 3Q3KB 4LORA 1KLOA 2BT7A 2Y38A 1DQBA 3V65B 1YUGA 3QMOA 2OYEP 1G1QA 5CKNA 2XC0L 5JVZA 2EI8B 1URKA 1HRFA 1RFNB 2BOHA 5CISA 2VH6B 4X8VL 1LPKA 4BTIA 2BZ6L 2J95B 4GU4A 3TH3L 3NTGA 3TZIA 5COXA 2P3FL 4X8SL 2BQ7A 2W3IB 1PXXA 3CA7A 3CENL 1ATDA 2B7DL 1G2LB 2P93L 4MMZB 4Z0KB 5JW1A 2Y82B 2JJLA 3F1SB 4RUTA 3S6XA 4OTYA 1EPIA 1IQJL 1Z6EL 2AYLA 3ZYGA 3ZYJB 1F0SB 2FLRL 3Q7DA 1FAXL 4CSYA 3HS7A 1N1IA 1NQLB 1OB1C 2VVUL 1Q4GA 2WYJB 3LTGD 3N8WA 1YO8A 3LAQA 3TK5B 1TOZA 5JBAE 1MQ6L 2UWLB 5I46L 1UZKA 1IQLL 1WHFA 5L2ZL 3TK6B 5CKMA 1HAFA 5JB9E 1DDXA 3PGHA 3M37L 3KQEL 5F19A 4ZXYL 4A7IA 4NA9L 4O02B 1EMOA 2WG4B 2XBWL 3ELAL 3MDLA 4ZAEB 3TBDA 2WFTA 3QCWA 4A94C 1P9JA 1F7MA 2XBVL 4X8UL 3GCXE 4Y7AB 1C5MF 3FCSB 2NPRA 2P3TA 1NFYB 2KNIA 3LN1A 2Y81B 1COUA 4BDWA 4YZUB 1CQEA 1UZJA 2BOXA 1Z6CA 4BTTA 4RRXA 1DVAL 1K36A 3LC5B 1HX2A 1CVWL 1KLJL 4XLWA 2W86A 2MGRA 3MQEA 2FLBL 1EPHA 1APQA 1EBVA 1A3PA 2OYUP 3BT2A 4Y76B 1KSNB 1IQIL 1F0RB 1IQGL 2P26A 2VJ3A 5CKQA 1ADXA 3ZYIB 1HJ7A 2UWOB 1V3XB 2VVVL 3N8XA 2W2PE 2D1JB 1SZBA 2JKHL 5K0HB 1CVUA 5JVYA 2WPHE 2PHBB 1FSBA 4JZEL 1L3YA 3KL6B 1G1SA 2BOKL 2DDUA 2HOXA 4JYVL 1EMNA 1K37A 1IGXA 1GK5A 2H9EL 4BXSA 3CS7L 1ATEA 4NGAL 1MOXC 1HCGB 2VWNL 3HO3A 2KB9A 1EPGA 2Y7ZB 2VH0B 4X8TL 1J9CL 2I9BA 4XBMA 4M10A 2BQ6A 1HT8A 1EAIC 2F9BL 4RS0A 3OLUA 2WPME 2HORA 1FFMA 1IQEL 1ZAQA 3M36L 2RNLA 5L30L 1W7XL 2H9EC 1IQKL 1CCVA 1WU1B 3N8YB 4Z6AL 4CUFA 1YGCL 1FF7A 4O1ZA 1XKAL 4TGFA 2Y7XB 3FBYA 2WYGB 3IITB 1CEJA 3DEMA 1NT0A 2XC5L 1FE2A 3HO4A 2YGPA 1EQGA 2BO2A 1LPGA 4XL1A 3N8ZA 2P3UA 4CUEA 1P0SL 3U73A 2GD4A 2PUQL 2M74A 2W2OE 3HS6A 1NFWB 2Y5FL 3HO5A 5JBBE 4ISHL 3N8YA 1MQ5L 1IVOC 1BF9A 2VVCK 4RRYA 3KQDL 2Y5GL 3LN0A 4Y71B 2Q1JB 1G1TA 1G1RA 2UWPB 2W2QE 4LMFA 5F1AA 3ASIA 1EZQB 1IOXA 2MHPA 2J34B 2VWMK 4ZH8B 4AQTA 2W2ME 2I9AA 3FFGL 1KLIL 1LPZA 3ENSA 2P16L 5JB8E 3HPTA 2WFXB 3SOBB 1DX5I 2BSFA 1JBUL 2K2SB 3SW2A 1KIGL 2BQWA 4ZHAB 1IGZA 3IJEB 3KQCL 3P5BL 5E8DA 5IKTA 2BMGA 2W26B 3H5CB 1IJQA 2WPKE 3V64C 3HS5A 1QIUA 4D0EA 2MGPA 1IQFL 1IP0A 1NPEB 2WPLE 6COXA 4JZFL 4MMXB 3RR3A 1HZ8A 1TPGA 3C9AC 4ZXXL 5IKRA 1DIYA 1YUKB 4G1MB 2P3FN 4CUDA 4E1GA 1B9WA 2FZZL 1ATAA 1ATBA 1IQHL 1WHEA 2YGQA 3KQBL 2P28B 1CX2A 2WPJE 4FM5A 1KKEA 4YT6L 5L2YL 3CFWA 3SOQA 1O5DL 3KRKA 1V1IA 2J2UB 2K2TA 3EGFA 2VWOL 2Y5HL 4NG9L 1CCFA 2XBXL 1UZQA 1HAEA 4BDXA 1APOA 1HT5A 3TGFA 3QH0A 1F7EA 5KIRA 2WG3C 1NFXB 1TLEA 3N8WB 1AUTL 4Y6DB 1XFEA 1X7AL 3BT1A 1HREA 5IKVA 1IQML 4Y7BB 4JYUL 1JV2B 2XC4L 1LK9A 2BOUA 1EGFA 1QFKL 1W8BL 2EI7B 2VRSA 3NTBA 1PRHA 1FAKL 1PTHA 3GISX 1LQDA 2KL7A 2PR3B 1M1XB 1LMJA 1YUFA 2G00L 1FJSL 1L5GB 4RRZA 2FD6A 1PFXL 2RA0L 1G2MB 4M11A 5KN5C 2TGFA 4D90A
chains in the Genus database with same CATH topology
2EI6B 3OLTA 3BPSE 1EQHA 3POYA 4ISIL 3LC3B 4MMYB 4Z0LA 1IQNL 4RRWA 1XKBA 3N8VA 3F6UL 1NZIA 2WPIE 2P95L 2P94L 3KCGL 3K9XA 3SOVA 4PH9A 1EPJA 1I0UA 2KV4A 3LTFB 1JL9A 2W3KB 2Y80B 2YGOA 4Y79B 4D0FA 4YT7L 2J38B 2FLGA 3KK6A 4BTUA 3GCWE 1UZPA 2CJIB 4OTJA 4COXA 1NFUB 1N7DA 4JZDL 2RHPA 3U7UG 5EGMB 2VWLL 5FDQA 1U8CB 1U67A 2WZPP 2ADXA 2J94B 1IOEL 3LIWB 5JBCE 4C16A 2J4IB 2XBYL 3R05A 1LMMA 5IKQA 3NJPC 1PGEA 3NT1A 2W2NE 4BXWA 1XDTR 3Q3KB 4LORA 1KLOA 2Y38A 1DQBA 3V65B 1YUGA 3QMOA 2OYEP 1G1QA 5CKNA 2XC0L 5JVZA 2EI8B 1URKA 1HRFA 1RFNB 2BOHA 5CISA 2VH6B 4X8VL 1LPKA 4BTIA 2BZ6L 2J95B 3TH3L 3NTGA 3TZIA 5COXA 2P3FL 4X8SL 2BQ7A 2W3IB 1PXXA 3CA7A 3CENL 1ATDA 2B7DL 1G2LB 2P93L 4MMZB 4Z0KB 5JW1A 2Y82B 3F1SB 4RUTA 3S6XA 4OTYA 1EPIA 1IQJL 1Z6EL 2AYLA 3ZYGA 3ZYJB 1F0SB 2FLRL 3Q7DA 1FAXL 4CSYA 3HS7A 1N1IA 1NQLB 1OB1C 2VVUL 1Q4GA 2WYJB 3LTGD 3N8WA 1YO8A 3LAQA 3TK5B 1TOZA 5JBAE 1MQ6L 2UWLB 5I46L 1UZKA 1IQLL 1WHFA 5L2ZL 3TK6B 5CKMA 1HAFA 5JB9E 1DDXA 3PGHA 3M37L 3KQEL 5F19A 4ZXYL 4A7IA 4NA9L 4O02B 1EMOA 2WG4B 2XBWL 3ELAL 3MDLA 4ZAEB 3TBDA 2WFTA 3QCWA 4A94C 1P9JA 1F7MA 2XBVL 4X8UL 3GCXE 4Y7AB 1C5MF 3FCSB 2NPRA 2P3TA 1NFYB 2KNIA 3LN1A 2Y81B 1COUA 4BDWA 4YZUB 1CQEA 1UZJA 2BOXA 1Z6CA 4BTTA 4RRXA 1DVAL 1K36A 3LC5B 1HX2A 1CVWL 1KLJL 4XLWA 2W86A 2MGRA 3MQEA 2FLBL 1EPHA 1APQA 1EBVA 1A3PA 2OYUP 3BT2A 4Y76B 1KSNB 1IQIL 1F0RB 1IQGL 2P26A 2VJ3A 5CKQA 1ADXA 3ZYIB 1HJ7A 2UWOB 1V3XB 2VVVL 3N8XA 2W2PE 2D1JB 1SZBA 2JKHL 5K0HB 1CVUA 5JVYA 2WPHE 2PHBB 1FSBA 4JZEL 1L3YA 3KL6B 1G1SA 2BOKL 2DDUA 4JYVL 1EMNA 1K37A 1IGXA 1GK5A 2H9EL 4BXSA 3CS7L 1ATEA 4NGAL 1MOXC 1HCGB 2VWNL 3HO3A 2KB9A 1EPGA 2Y7ZB 2VH0B 4X8TL 1J9CL 2I9BA 4XBMA 4M10A 2BQ6A 1HT8A 1EAIC 2F9BL 4RS0A 3OLUA 2WPME 1FFMA 1IQEL 1ZAQA 3M36L 2RNLA 5L30L 1W7XL 2H9EC 1IQKL 1CCVA 1WU1B 3N8YB 4Z6AL 4CUFA 1YGCL 1FF7A 4O1ZA 1XKAL 4TGFA 2Y7XB 3FBYA 2WYGB 3IITB 1CEJA 3DEMA 1NT0A 2XC5L 1FE2A 3HO4A 2YGPA 1EQGA 2BO2A 1LPGA 4XL1A 3N8ZA 2P3UA 4CUEA 1P0SL 3U73A 2GD4A 2PUQL 2M74A 2W2OE 3HS6A 1NFWB 2Y5FL 3HO5A 5JBBE 4ISHL 3N8YA 1MQ5L 1IVOC 1BF9A 2VVCK 4RRYA 3KQDL 2Y5GL 3LN0A 4Y71B 2Q1JB 1G1TA 1G1RA 2UWPB 2W2QE 4LMFA 5F1AA 3ASIA 1EZQB 1IOXA 2MHPA 2J34B 2VWMK 4ZH8B 4AQTA 2W2ME 2I9AA 3FFGL 1KLIL 1LPZA 3ENSA 2P16L 5JB8E 3HPTA 2WFXB 3SOBB 1DX5I 1JBUL 2K2SB 3SW2A 1KIGL 2BQWA 4ZHAB 1IGZA 3IJEB 3KQCL 3P5BL 5E8DA 5IKTA 2BMGA 2W26B 3H5CB 1IJQA 2WPKE 3V64C 3HS5A 4D0EA 2MGPA 1IQFL 1IP0A 1NPEB 2WPLE 6COXA 4JZFL 4MMXB 3RR3A 1HZ8A 1TPGA 3C9AC 4ZXXL 5IKRA 1DIYA 1YUKB 4G1MB 2P3FN 4CUDA 4E1GA 1B9WA 2FZZL 1ATAA 1ATBA 1IQHL 1WHEA 2YGQA 3KQBL 2P28B 1CX2A 2WPJE 4FM5A 4YT6L 5L2YL 3CFWA 3SOQA 1O5DL 3KRKA 2J2UB 2K2TA 3EGFA 2VWOL 2Y5HL 4NG9L 1CCFA 2XBXL 1UZQA 1HAEA 4BDXA 1APOA 1HT5A 3TGFA 3QH0A 1F7EA 5KIRA 2WG3C 1NFXB 1TLEA 3N8WB 1AUTL 4Y6DB 1XFEA 1X7AL 3BT1A 1HREA 5IKVA 1IQML 4Y7BB 4JYUL 1JV2B 2XC4L 2BOUA 1EGFA 1QFKL 1W8BL 2EI7B 3NTBA 1PRHA 1FAKL 1PTHA 3GISX 1LQDA 2KL7A 2PR3B 1M1XB 1LMJA 1YUFA 2G00L 1FJSL 1L5GB 4RRZA 2FD6A 1PFXL 2RA0L 1G2MB 4M11A 5KN5C 2TGFA 4D90A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EI6 B;  3OLT A;  3BPS E;  1EQH A;  3POY A;  4ISI L;  3LC3 B;  4MMY B;  4Z0L A;  1IQN L;  4RRW A;  1XKB A;  3N8V A;  3F6U L;  1NZI A;  2WPI E;  2P95 L;  2P94 L;  3KCG L;  3K9X A;  3SOV A;  4PH9 A;  1EPJ A;  1I0U A;  2KV4 A;  3LTF B;  1JL9 A;  2W3K B;  2Y80 B;  2YGO A;  4Y79 B;  4D0F A;  4YT7 L;  2J38 B;  2FLG A;  3KK6 A;  4BTU A;  3GCW E;  1UZP A;  2CJI B;  4OTJ A;  4COX A;  1NFU B;  1N7D A;  4JZD L;  2RHP A;  3U7U G;  5EGM B;  2VWL L;  5FDQ A;  1U8C B;  1U67 A;  2ADX A;  2J94 B;  1IOE L;  3LIW B;  5JBC E;  4C16 A;  2J4I B;  2XBY L;  3R05 A;  5IKQ A;  3NJP C;  1PGE A;  3NT1 A;  2W2N E;  4BXW A;  1XDT R;  3Q3K B;  4LOR A;  1KLO A;  2Y38 A;  1DQB A;  3V65 B;  1YUG A;  3QMO A;  2OYE P;  1G1Q A;  5CKN A;  2XC0 L;  5JVZ A;  2EI8 B;  1URK A;  1HRF A;  1RFN B;  2BOH A;  5CIS A;  2VH6 B;  4X8V L;  1LPK A;  4BTI A;  2BZ6 L;  2J95 B;  3TH3 L;  3NTG A;  3TZI A;  5COX A;  2P3F L;  4X8S L;  2BQ7 A;  2W3I B;  1PXX A;  3CA7 A;  3CEN L;  1ATD A;  2B7D L;  1G2L B;  2P93 L;  4MMZ B;  4Z0K B;  5JW1 A;  2Y82 B;  3F1S B;  4RUT A;  4OTY A;  1EPI A;  1IQJ L;  1Z6E L;  2AYL A;  3ZYG A;  3ZYJ B;  1F0S B;  2FLR L;  3Q7D A;  1FAX L;  4CSY A;  3HS7 A;  1N1I A;  1NQL B;  1OB1 C;  2VVU L;  1Q4G A;  2WYJ B;  3LTG D;  3N8W A;  1YO8 A;  3LAQ A;  3TK5 B;  1TOZ A;  5JBA E;  1MQ6 L;  2UWL B;  5I46 L;  1UZK A;  1IQL L;  1WHF A;  5L2Z L;  3TK6 B;  5CKM A;  1HAF A;  5JB9 E;  1DDX A;  3PGH A;  3M37 L;  3KQE L;  5F19 A;  4ZXY L;  4A7I A;  4NA9 L;  4O02 B;  1EMO A;  2WG4 B;  2XBW L;  3ELA L;  3MDL A;  4ZAE B;  3TBD A;  2WFT A;  3QCW A;  1P9J A;  1F7M A;  2XBV L;  4X8U L;  3GCX E;  4Y7A B;  1C5M F;  3FCS B;  2NPR A;  2P3T A;  1NFY B;  3LN1 A;  2Y81 B;  1COU A;  4BDW A;  4YZU B;  1CQE A;  1UZJ A;  2BOX A;  1Z6C A;  4BTT A;  4RRX A;  1DVA L;  1K36 A;  3LC5 B;  1HX2 A;  1CVW L;  1KLJ L;  4XLW A;  2W86 A;  2MGR A;  3MQE A;  2FLB L;  1EPH A;  1APQ A;  1EBV A;  1A3P A;  2OYU P;  3BT2 A;  4Y76 B;  1KSN B;  1IQI L;  1F0R B;  1IQG L;  2P26 A;  2VJ3 A;  5CKQ A;  1ADX A;  3ZYI B;  1HJ7 A;  2UWO B;  1V3X B;  2VVV L;  3N8X A;  2W2P E;  2D1J B;  1SZB A;  2JKH L;  5K0H B;  1CVU A;  5JVY A;  2WPH E;  2PHB B;  1FSB A;  4JZE L;  1L3Y A;  3KL6 B;  1G1S A;  2BOK L;  2DDU A;  4JYV L;  1EMN A;  1K37 A;  1IGX A;  1GK5 A;  2H9E L;  4BXS A;  3CS7 L;  1ATE A;  4NGA L;  1MOX C;  1HCG B;  2VWN L;  3HO3 A;  2KB9 A;  1EPG A;  2Y7Z B;  2VH0 B;  4X8T L;  1J9C L;  2I9B A;  4XBM A;  4M10 A;  2BQ6 A;  1HT8 A;  1EAI C;  2F9B L;  4RS0 A;  3OLU A;  2WPM E;  1FFM A;  1IQE L;  1ZAQ A;  3M36 L;  2RNL A;  5L30 L;  1W7X L;  1IQK L;  1CCV A;  1WU1 B;  3N8Y B;  4Z6A L;  4CUF A;  1YGC L;  1FF7 A;  4O1Z A;  1XKA L;  4TGF A;  2Y7X B;  3FBY A;  2WYG B;  3IIT B;  1CEJ A;  3DEM A;  1NT0 A;  2XC5 L;  1FE2 A;  3HO4 A;  2YGP A;  1EQG A;  2BO2 A;  1LPG A;  4XL1 A;  3N8Z A;  2P3U A;  4CUE A;  1P0S L;  3U73 A;  2GD4 A;  2PUQ L;  2M74 A;  2W2O E;  3HS6 A;  1NFW B;  2Y5F L;  3HO5 A;  5JBB E;  4ISH L;  3N8Y A;  1MQ5 L;  1IVO C;  1BF9 A;  2VVC K;  4RRY A;  3KQD L;  2Y5G L;  3LN0 A;  4Y71 B;  2Q1J B;  1G1T A;  1G1R A;  2UWP B;  2W2Q E;  4LMF A;  5F1A A;  3ASI A;  1EZQ B;  1IOX A;  2MHP A;  2J34 B;  2VWM K;  4ZH8 B;  4AQT A;  2W2M E;  2I9A A;  3FFG L;  1KLI L;  1LPZ A;  3ENS A;  2P16 L;  5JB8 E;  3HPT A;  2WFX B;  3SOB B;  1DX5 I;  1JBU L;  2K2S B;  3SW2 A;  1KIG L;  2BQW A;  4ZHA B;  1IGZ A;  3IJE B;  3KQC L;  3P5B L;  5E8D A;  5IKT A;  2BMG A;  2W26 B;  3H5C B;  1IJQ A;  2WPK E;  3V64 C;  3HS5 A;  4D0E A;  2MGP A;  1IQF L;  1IP0 A;  1NPE B;  2WPL E;  6COX A;  4JZF L;  4MMX B;  3RR3 A;  1HZ8 A;  1TPG A;  3C9A C;  4ZXX L;  5IKR A;  1DIY A;  1YUK B;  4G1M B;  2P3F N;  4CUD A;  4E1G A;  1B9W A;  2FZZ L;  1ATA A;  1ATB A;  1IQH L;  1WHE A;  3KQB L;  2P28 B;  1CX2 A;  2WPJ E;  4FM5 A;  4YT6 L;  5L2Y L;  3CFW A;  3SOQ A;  1O5D L;  3KRK A;  2J2U B;  2K2T A;  3EGF A;  2VWO L;  2Y5H L;  4NG9 L;  1CCF A;  2XBX L;  1UZQ A;  1HAE A;  4BDX A;  1APO A;  1HT5 A;  3TGF A;  3QH0 A;  1F7E A;  5KIR A;  2WG3 C;  1NFX B;  1TLE A;  3N8W B;  1AUT L;  4Y6D B;  1XFE A;  1X7A L;  3BT1 A;  1HRE A;  5IKV A;  1IQM L;  4Y7B B;  4JYU L;  1JV2 B;  2XC4 L;  2BOU A;  1EGF A;  1QFK L;  1W8B L;  2EI7 B;  3NTB A;  1PRH A;  1FAK L;  1PTH A;  3GIS X;  1LQD A;  2KL7 A;  2PR3 B;  1M1X B;  1LMJ A;  1YUF A;  2G00 L;  1FJS L;  1L5G B;  4RRZ A;  2FD6 A;  1PFX L;  2RA0 L;  1G2M B;  4M11 A;  5KN5 C;  2TGF A;  4D90 A; 
#chains in the Genus database with same CATH topology
 2EI6 B;  3OLT A;  3BPS E;  1EQH A;  3POY A;  4ISI L;  3LC3 B;  4MMY B;  4Z0L A;  1IQN L;  4RRW A;  1XKB A;  3N8V A;  3F6U L;  1NZI A;  2WPI E;  2P95 L;  2P94 L;  3KCG L;  3K9X A;  3SOV A;  4PH9 A;  1EPJ A;  1I0U A;  2KV4 A;  3LTF B;  1JL9 A;  2W3K B;  2Y80 B;  2YGO A;  4Y79 B;  4D0F A;  4YT7 L;  2J38 B;  1V1H A;  2FLG A;  3KK6 A;  4GU3 A;  4BTU A;  3GCW E;  1UZP A;  2CJI B;  4OTJ A;  4COX A;  2BT8 A;  1NFU B;  1N7D A;  4JZD L;  2RHP A;  3U7U G;  5EGM B;  2VWL L;  5FDQ A;  1U8C B;  1U67 A;  2WZP P;  2ADX A;  2J94 B;  1IOE L;  3LIW B;  5JBC E;  4C16 A;  2J4I B;  2XBY L;  3R05 A;  1LMM A;  5IKQ A;  3NJP C;  1PGE A;  3NT1 A;  2W2N E;  4BXW A;  1XDT R;  3Q3K B;  4LOR A;  1KLO A;  2BT7 A;  2Y38 A;  1DQB A;  3V65 B;  1YUG A;  3QMO A;  2OYE P;  1G1Q A;  5CKN A;  2XC0 L;  5JVZ A;  2EI8 B;  1URK A;  1HRF A;  1RFN B;  2BOH A;  5CIS A;  2VH6 B;  4X8V L;  1LPK A;  4BTI A;  2BZ6 L;  2J95 B;  4GU4 A;  3TH3 L;  3NTG A;  3TZI A;  5COX A;  2P3F L;  4X8S L;  2BQ7 A;  2W3I B;  1PXX A;  3CA7 A;  3CEN L;  1ATD A;  2B7D L;  1G2L B;  2P93 L;  4MMZ B;  4Z0K B;  5JW1 A;  2Y82 B;  2JJL A;  3F1S B;  4RUT A;  3S6X A;  4OTY A;  1EPI A;  1IQJ L;  1Z6E L;  2AYL A;  3ZYG A;  3ZYJ B;  1F0S B;  2FLR L;  3Q7D A;  1FAX L;  4CSY A;  3HS7 A;  1N1I A;  1NQL B;  1OB1 C;  2VVU L;  1Q4G A;  2WYJ B;  3LTG D;  3N8W A;  1YO8 A;  3LAQ A;  3TK5 B;  1TOZ A;  5JBA E;  1MQ6 L;  2UWL B;  5I46 L;  1UZK A;  1IQL L;  1WHF A;  5L2Z L;  3TK6 B;  5CKM A;  1HAF A;  5JB9 E;  1DDX A;  3PGH A;  3M37 L;  3KQE L;  5F19 A;  4ZXY L;  4A7I A;  4NA9 L;  4O02 B;  1EMO A;  2WG4 B;  2XBW L;  3ELA L;  3MDL A;  4ZAE B;  3TBD A;  2WFT A;  3QCW A;  4A94 C;  1P9J A;  1F7M A;  2XBV L;  4X8U L;  3GCX E;  4Y7A B;  1C5M F;  3FCS B;  2NPR A;  2P3T A;  1NFY B;  2KNI A;  3LN1 A;  2Y81 B;  1COU A;  4BDW A;  4YZU B;  1CQE A;  1UZJ A;  2BOX A;  1Z6C A;  4BTT A;  4RRX A;  1DVA L;  1K36 A;  3LC5 B;  1HX2 A;  1CVW L;  1KLJ L;  4XLW A;  2W86 A;  2MGR A;  3MQE A;  2FLB L;  1EPH A;  1APQ A;  1EBV A;  1A3P A;  2OYU P;  3BT2 A;  4Y76 B;  1KSN B;  1IQI L;  1F0R B;  1IQG L;  2P26 A;  2VJ3 A;  5CKQ A;  1ADX A;  3ZYI B;  1HJ7 A;  2UWO B;  1V3X B;  2VVV L;  3N8X A;  2W2P E;  2D1J B;  1SZB A;  2JKH L;  5K0H B;  1CVU A;  5JVY A;  2WPH E;  2PHB B;  1FSB A;  4JZE L;  1L3Y A;  3KL6 B;  1G1S A;  2BOK L;  2DDU A;  2HOX A;  4JYV L;  1EMN A;  1K37 A;  1IGX A;  1GK5 A;  2H9E L;  4BXS A;  3CS7 L;  1ATE A;  4NGA L;  1MOX C;  1HCG B;  2VWN L;  3HO3 A;  2KB9 A;  1EPG A;  2Y7Z B;  2VH0 B;  4X8T L;  1J9C L;  2I9B A;  4XBM A;  4M10 A;  2BQ6 A;  1HT8 A;  1EAI C;  2F9B L;  4RS0 A;  3OLU A;  2WPM E;  2HOR A;  1FFM A;  1IQE L;  1ZAQ A;  3M36 L;  2RNL A;  5L30 L;  1W7X L;  2H9E C;  1IQK L;  1CCV A;  1WU1 B;  3N8Y B;  4Z6A L;  4CUF A;  1YGC L;  1FF7 A;  4O1Z A;  1XKA L;  4TGF A;  2Y7X B;  3FBY A;  2WYG B;  3IIT B;  1CEJ A;  3DEM A;  1NT0 A;  2XC5 L;  1FE2 A;  3HO4 A;  2YGP A;  1EQG A;  2BO2 A;  1LPG A;  4XL1 A;  3N8Z A;  2P3U A;  4CUE A;  1P0S L;  3U73 A;  2GD4 A;  2PUQ L;  2M74 A;  2W2O E;  3HS6 A;  1NFW B;  2Y5F L;  3HO5 A;  5JBB E;  4ISH L;  3N8Y A;  1MQ5 L;  1IVO C;  1BF9 A;  2VVC K;  4RRY A;  3KQD L;  2Y5G L;  3LN0 A;  4Y71 B;  2Q1J B;  1G1T A;  1G1R A;  2UWP B;  2W2Q E;  4LMF A;  5F1A A;  3ASI A;  1EZQ B;  1IOX A;  2MHP A;  2J34 B;  2VWM K;  4ZH8 B;  4AQT A;  2W2M E;  2I9A A;  3FFG L;  1KLI L;  1LPZ A;  3ENS A;  2P16 L;  5JB8 E;  3HPT A;  2WFX B;  3SOB B;  1DX5 I;  2BSF A;  1JBU L;  2K2S B;  3SW2 A;  1KIG L;  2BQW A;  4ZHA B;  1IGZ A;  3IJE B;  3KQC L;  3P5B L;  5E8D A;  5IKT A;  2BMG A;  2W26 B;  3H5C B;  1IJQ A;  2WPK E;  3V64 C;  3HS5 A;  1QIU A;  4D0E A;  2MGP A;  1IQF L;  1IP0 A;  1NPE B;  2WPL E;  6COX A;  4JZF L;  4MMX B;  3RR3 A;  1HZ8 A;  1TPG A;  3C9A C;  4ZXX L;  5IKR A;  1DIY A;  1YUK B;  4G1M B;  2P3F N;  4CUD A;  4E1G A;  1B9W A;  2FZZ L;  1ATA A;  1ATB A;  1IQH L;  1WHE A;  2YGQ A;  3KQB L;  2P28 B;  1CX2 A;  2WPJ E;  4FM5 A;  1KKE A;  4YT6 L;  5L2Y L;  3CFW A;  3SOQ A;  1O5D L;  3KRK A;  1V1I A;  2J2U B;  2K2T A;  3EGF A;  2VWO L;  2Y5H L;  4NG9 L;  1CCF A;  2XBX L;  1UZQ A;  1HAE A;  4BDX A;  1APO A;  1HT5 A;  3TGF A;  3QH0 A;  1F7E A;  5KIR A;  2WG3 C;  1NFX B;  1TLE A;  3N8W B;  1AUT L;  4Y6D B;  1XFE A;  1X7A L;  3BT1 A;  1HRE A;  5IKV A;  1IQM L;  4Y7B B;  4JYU L;  1JV2 B;  2XC4 L;  1LK9 A;  2BOU A;  1EGF A;  1QFK L;  1W8B L;  2EI7 B;  2VRS A;  3NTB A;  1PRH A;  1FAK L;  1PTH A;  3GIS X;  1LQD A;  2KL7 A;  2PR3 B;  1M1X B;  1LMJ A;  1YUF A;  2G00 L;  1FJS L;  1L5G B;  4RRZ A;  2FD6 A;  1PFX L;  2RA0 L;  1G2M B;  4M11 A;  5KN5 C;  2TGF A;  4D90 A; 
#chains in the Genus database with same CATH homology
 2EI6 B;  3OLT A;  3BPS E;  1EQH A;  3POY A;  4ISI L;  3LC3 B;  4MMY B;  4Z0L A;  1IQN L;  4RRW A;  1XKB A;  3N8V A;  3F6U L;  1NZI A;  2WPI E;  2P95 L;  2P94 L;  3KCG L;  3K9X A;  3SOV A;  4PH9 A;  1EPJ A;  1I0U A;  2KV4 A;  3LTF B;  1JL9 A;  2W3K B;  2Y80 B;  2YGO A;  4Y79 B;  4D0F A;  4YT7 L;  2J38 B;  2FLG A;  3KK6 A;  4BTU A;  3GCW E;  1UZP A;  2CJI B;  4OTJ A;  4COX A;  1NFU B;  1N7D A;  4JZD L;  2RHP A;  3U7U G;  5EGM B;  2VWL L;  5FDQ A;  1U8C B;  1U67 A;  2WZP P;  2ADX A;  2J94 B;  1IOE L;  3LIW B;  5JBC E;  4C16 A;  2J4I B;  2XBY L;  3R05 A;  1LMM A;  5IKQ A;  3NJP C;  1PGE A;  3NT1 A;  2W2N E;  4BXW A;  1XDT R;  3Q3K B;  4LOR A;  1KLO A;  2Y38 A;  1DQB A;  3V65 B;  1YUG A;  3QMO A;  2OYE P;  1G1Q A;  5CKN A;  2XC0 L;  5JVZ A;  2EI8 B;  1URK A;  1HRF A;  1RFN B;  2BOH A;  5CIS A;  2VH6 B;  4X8V L;  1LPK A;  4BTI A;  2BZ6 L;  2J95 B;  3TH3 L;  3NTG A;  3TZI A;  5COX A;  2P3F L;  4X8S L;  2BQ7 A;  2W3I B;  1PXX A;  3CA7 A;  3CEN L;  1ATD A;  2B7D L;  1G2L B;  2P93 L;  4MMZ B;  4Z0K B;  5JW1 A;  2Y82 B;  3F1S B;  4RUT A;  3S6X A;  4OTY A;  1EPI A;  1IQJ L;  1Z6E L;  2AYL A;  3ZYG A;  3ZYJ B;  1F0S B;  2FLR L;  3Q7D A;  1FAX L;  4CSY A;  3HS7 A;  1N1I A;  1NQL B;  1OB1 C;  2VVU L;  1Q4G A;  2WYJ B;  3LTG D;  3N8W A;  1YO8 A;  3LAQ A;  3TK5 B;  1TOZ A;  5JBA E;  1MQ6 L;  2UWL B;  5I46 L;  1UZK A;  1IQL L;  1WHF A;  5L2Z L;  3TK6 B;  5CKM A;  1HAF A;  5JB9 E;  1DDX A;  3PGH A;  3M37 L;  3KQE L;  5F19 A;  4ZXY L;  4A7I A;  4NA9 L;  4O02 B;  1EMO A;  2WG4 B;  2XBW L;  3ELA L;  3MDL A;  4ZAE B;  3TBD A;  2WFT A;  3QCW A;  4A94 C;  1P9J A;  1F7M A;  2XBV L;  4X8U L;  3GCX E;  4Y7A B;  1C5M F;  3FCS B;  2NPR A;  2P3T A;  1NFY B;  2KNI A;  3LN1 A;  2Y81 B;  1COU A;  4BDW A;  4YZU B;  1CQE A;  1UZJ A;  2BOX A;  1Z6C A;  4BTT A;  4RRX A;  1DVA L;  1K36 A;  3LC5 B;  1HX2 A;  1CVW L;  1KLJ L;  4XLW A;  2W86 A;  2MGR A;  3MQE A;  2FLB L;  1EPH A;  1APQ A;  1EBV A;  1A3P A;  2OYU P;  3BT2 A;  4Y76 B;  1KSN B;  1IQI L;  1F0R B;  1IQG L;  2P26 A;  2VJ3 A;  5CKQ A;  1ADX A;  3ZYI B;  1HJ7 A;  2UWO B;  1V3X B;  2VVV L;  3N8X A;  2W2P E;  2D1J B;  1SZB A;  2JKH L;  5K0H B;  1CVU A;  5JVY A;  2WPH E;  2PHB B;  1FSB A;  4JZE L;  1L3Y A;  3KL6 B;  1G1S A;  2BOK L;  2DDU A;  4JYV L;  1EMN A;  1K37 A;  1IGX A;  1GK5 A;  2H9E L;  4BXS A;  3CS7 L;  1ATE A;  4NGA L;  1MOX C;  1HCG B;  2VWN L;  3HO3 A;  2KB9 A;  1EPG A;  2Y7Z B;  2VH0 B;  4X8T L;  1J9C L;  2I9B A;  4XBM A;  4M10 A;  2BQ6 A;  1HT8 A;  1EAI C;  2F9B L;  4RS0 A;  3OLU A;  2WPM E;  1FFM A;  1IQE L;  1ZAQ A;  3M36 L;  2RNL A;  5L30 L;  1W7X L;  2H9E C;  1IQK L;  1CCV A;  1WU1 B;  3N8Y B;  4Z6A L;  4CUF A;  1YGC L;  1FF7 A;  4O1Z A;  1XKA L;  4TGF A;  2Y7X B;  3FBY A;  2WYG B;  3IIT B;  1CEJ A;  3DEM A;  1NT0 A;  2XC5 L;  1FE2 A;  3HO4 A;  2YGP A;  1EQG A;  2BO2 A;  1LPG A;  4XL1 A;  3N8Z A;  2P3U A;  4CUE A;  1P0S L;  3U73 A;  2GD4 A;  2PUQ L;  2M74 A;  2W2O E;  3HS6 A;  1NFW B;  2Y5F L;  3HO5 A;  5JBB E;  4ISH L;  3N8Y A;  1MQ5 L;  1IVO C;  1BF9 A;  2VVC K;  4RRY A;  3KQD L;  2Y5G L;  3LN0 A;  4Y71 B;  2Q1J B;  1G1T A;  1G1R A;  2UWP B;  2W2Q E;  4LMF A;  5F1A A;  3ASI A;  1EZQ B;  1IOX A;  2MHP A;  2J34 B;  2VWM K;  4ZH8 B;  4AQT A;  2W2M E;  2I9A A;  3FFG L;  1KLI L;  1LPZ A;  3ENS A;  2P16 L;  5JB8 E;  3HPT A;  2WFX B;  3SOB B;  1DX5 I;  1JBU L;  2K2S B;  3SW2 A;  1KIG L;  2BQW A;  4ZHA B;  1IGZ A;  3IJE B;  3KQC L;  3P5B L;  5E8D A;  5IKT A;  2BMG A;  2W26 B;  3H5C B;  1IJQ A;  2WPK E;  3V64 C;  3HS5 A;  4D0E A;  2MGP A;  1IQF L;  1IP0 A;  1NPE B;  2WPL E;  6COX A;  4JZF L;  4MMX B;  3RR3 A;  1HZ8 A;  1TPG A;  3C9A C;  4ZXX L;  5IKR A;  1DIY A;  1YUK B;  4G1M B;  2P3F N;  4CUD A;  4E1G A;  1B9W A;  2FZZ L;  1ATA A;  1ATB A;  1IQH L;  1WHE A;  2YGQ A;  3KQB L;  2P28 B;  1CX2 A;  2WPJ E;  4FM5 A;  4YT6 L;  5L2Y L;  3CFW A;  3SOQ A;  1O5D L;  3KRK A;  2J2U B;  2K2T A;  3EGF A;  2VWO L;  2Y5H L;  4NG9 L;  1CCF A;  2XBX L;  1UZQ A;  1HAE A;  4BDX A;  1APO A;  1HT5 A;  3TGF A;  3QH0 A;  1F7E A;  5KIR A;  2WG3 C;  1NFX B;  1TLE A;  3N8W B;  1AUT L;  4Y6D B;  1XFE A;  1X7A L;  3BT1 A;  1HRE A;  5IKV A;  1IQM L;  4Y7B B;  4JYU L;  1JV2 B;  2XC4 L;  2BOU A;  1EGF A;  1QFK L;  1W8B L;  2EI7 B;  3NTB A;  1PRH A;  1FAK L;  1PTH A;  3GIS X;  1LQD A;  2KL7 A;  2PR3 B;  1M1X B;  1LMJ A;  1YUF A;  2G00 L;  1FJS L;  1L5G B;  4RRZ A;  2FD6 A;  1PFX L;  2RA0 L;  1G2M B;  4M11 A;  5KN5 C;  2TGF A;  4D90 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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