2G00L

Factor xa in complex with the inhibitor 3-(6-(2'-((dimethylamino)methyl)-4-biphenylyl)-7-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1h-pyrazolo[3,4-c]pyridin-1-yl)benzamide
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Coagulation factor X
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2006-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2g00L00
3CA7A 1N7DA 1IVOC 1HZ8A 1LPGA 1FE2A 4XBMA 4LMFA 1L5GB 3NT1A 2KV4A 4AQTA 1Q4GA 5CKQA 2P94L 4X8TL 1UZJA 3GISX 2Y5GL 3SOBB 1CVUA 1EQHA 3H5CB 3IJEB 2J34B 5IKQA 3HPTA 4O1ZA 2D1JB 2VWNL 4CUDA 2BQWA 4ISIL 3P5BL 1IQEL 3ENSA 2WG3C 2XBWL 3LTGD 1MOXC 2G00L 1LPKA 4ZH8B 3GCXE 1M1XB 2WFXB 1LQDA 3QMOA 2PUQL 2Y7ZB 1DQBA 2KB9A 3KQCL 1IQIL 2J4IB 2P3FN 1COUA 3C9AC 1W7XL 2W2NE 1B9WA 3HS7A 1HAFA 2EI6B 1F7MA 2BOHA 2P3UA 1W8BL 1EQGA 3U7UG 1PFXL 1EAIC 3FBYA 1LPZA 4M10A 4FM5A 1CQEA 3KL6B 1XKBA 1YO8A 2J38B 5COXA 2BMGA 3BT2A 1P0SL 2BOKL 1EPJA 1WHEA 2P3FL 3K9XA 2WPKE 1HRFA 2UWLB 1LMJA 2BO2A 3ZYIB 3SOVA 2W2OE 2P26A 2XBVL 4MMXB 2B7DL 2XC0L 3KQDL 3TGFA 5CISA 1NFWB 3ASIA 3IITB 1HT5A 5IKTA 2OYEP 2BOUA 4RRWA 3V64C 3M36L 4ZXYL 1G1TA 3GCWE 2YGPA 1HCGB 1XKAL 4BXWA 2K2TA 1G2MB 4G1MB 3POYA 3LN0A 3NTGA 1NPEB 1EBVA 3RR3A 4TGFA 2XC4L 1PGEA 1APOA 1IOXA 1C5MF 1I0UA 1IQNL 2VH0B 5IKVA 2BZ6L 4COXA 3QCWA 1IQML 1FAKL 1V3XB 4Y7AB 1XFEA 2VVUL 5JBAE 2VVVL 1EPIA 1CCFA 1Z6CA 3CENL 1IGXA 1L3YA 2DDUA 4BXSA 2FLGA 2YGOA 3TK6B 1FJSL 2W86A 3NTBA 2H9EL 4Z6AL 1CVWL 4BTTA 4YT6L 2Y81B 1APQA 1IQKL 2W26B 4PH9A 2VWMK 4D0FA 1DDXA 1G2LB 1KLIL 1DX5I 1JL9A 3Q7DA 2VH6B 3MDLA 3N8WB 4A7IA 1IP0A 1YGCL 2I9AA 3N8XA 4CUEA 2BQ6A 3LC5B 2RHPA 2WPHE 1JV2B 2XC5L 1IQLL 1WHFA 2P28B 4JYVL 2K2SB 1HT8A 1IQGL 1FAXL 1F0RB 2Y5FL 3DEMA 4M11A 4MMZB 4MMYB 1KSNB 4RRZA 4JYUL 2WFTA 4Y7BB 1WU1B 1NFUB 2Y5HL 5L2YL 1O5DL 3V65B 5F1AA 1CCVA 2RA0L 3KRKA 2W2PE 1URKA 1OB1C 4D0EA 2TGFA 3F6UL 1MQ5L 1NQLB 3EGFA 3OLUA 1IGZA 3U73A 1DIYA 2P3TA 4JZDL 1FF7A 5IKRA 1K36A 2MHPA 1EMNA 2WYJB 3HO3A 2PR3B 3MQEA 3QH0A 2P93L 4RUTA 1EGFA 1F0SB 3PGHA 3OLTA 4C16A 5KN5C 1KLOA 4BTUA 2JKHL 2P95L 2Y38A 1IQHL 6COXA 4Y6DB 2PHBB 1HAEA 4X8SL 3CS7L 1J9CL 2UWPB 2BOXA 5E8DA 2MGPA 1UZQA 4LORA 3BPSE 1IQFL 2VJ3A 1EMOA 1IQJL 1NZIA 4X8UL 4YT7L 1KIGL 4JZFL 4ISHL 1YUKB 1K37A 4YZUB 3N8VA 1HX2A 5JVZA 3SW2A 2OYUP 1CEJA 1GK5A 5CKNA 1X7AL 2BQ7A 4BDWA 3CFWA 1QFKL 3F1SB 5K0HB 1EPGA 2FLBL 2WPME 4Y71B 4O02B 2WG4B 3LN1A 1TLEA 4JZEL 4RRYA 2WPJE 4Y79B 1P9JA 1ATDA 5FDQA 2VVCK 2XBXL 4CUFA 2Y7XB 5JB8E 5JVYA 5KIRA 3TZIA 1DVAL 1CX2A 4OTJA 3KQBL 1MQ6L 1EPHA 1G1QA 1IJQA 4XLWA 3N8YA 1UZPA 1JBUL 3TH3L 4NA9L 1NFYB 2FZZL 2GD4A 3FFGL 2FD6A 2Q1JB 5JB9E 5F19A 4CSYA 4Y76B 1EZQB 1TOZA 1NT0A 3TBDA 4NG9L 3ELAL 4ZHAB 2EI8B 5JBBE 1FSBA 2W3IB 3ZYGA 1AUTL 5EGMB 3KCGL 4ZXXL 1N1IA 1U67A 2J94B 1XDTR 2EI7B 4XL1A 3N8YB 1HJ7A 5L2ZL 2KL7A 3M37L 1PRHA 1HREA 3LAQA 1F7EA 5JBCE 2VWLL 1KLJL 3FCSB 3KK6A 3LTFB 2J2UB 4OTYA 2I9BA 2VWOL 1FFMA 3N8ZA 2W2ME 2UWOB 1ADXA 2XBYL 4ZAEB 2P16L 2M74A 5CKMA 3Q3KB 2W3KB 1IOEL 3KQEL 1PTHA 1TPGA 1PXXA 1U8CB 2CJIB 1A3PA 1G1RA 2ADXA 2W2QE 1RFNB 5L30L 1YUFA 1ATBA 2FLRL 3NJPC 3TK5B 4X8VL 3HO4A 4BTIA 1BF9A 1Z6EL 4Z0KB 2Y80B 3SOQA 1ZAQA 1NFXB 2WPIE 5I46L 1G1SA 4Z0LA 1ATEA 3HO5A 3ZYJB 5JW1A 3HS5A 2J95B 3HS6A 4NGAL 2AYLA 4BDXA 2MGRA 1ATAA 4E1GA 1UZKA 2Y82B 2NPRA 3LC3B 3R05A 4RRXA 1YUGA 4D90A 2WYGB 2F9BL 3N8WA 4RS0A 3LIWB 1SZBA 2WPLE 2RNLA 3BT1A
chains in the Genus database with same CATH superfamily
3CA7A 1N7DA 1IVOC 1HZ8A 1LPGA 1FE2A 4XBMA 4LMFA 1L5GB 3NT1A 2KV4A 4AQTA 1Q4GA 5CKQA 2P94L 4X8TL 1UZJA 3GISX 2Y5GL 3SOBB 1CVUA 1EQHA 3H5CB 3IJEB 2J34B 5IKQA 3HPTA 4O1ZA 2D1JB 2VWNL 4CUDA 2BQWA 4ISIL 3P5BL 1IQEL 3ENSA 2WG3C 2XBWL 3LTGD 1MOXC 2G00L 2KNIA 1LPKA 4ZH8B 3GCXE 1M1XB 2WFXB 1LQDA 3QMOA 2PUQL 2Y7ZB 1DQBA 2KB9A 3KQCL 1V1IA 1IQIL 2J4IB 2P3FN 1COUA 3C9AC 1W7XL 2W2NE 1B9WA 3HS7A 1HAFA 2EI6B 1F7MA 2BOHA 2P3UA 1W8BL 1EQGA 3U7UG 1PFXL 1EAIC 3FBYA 1LPZA 4M10A 4FM5A 1CQEA 3KL6B 1XKBA 1YO8A 2J38B 5COXA 2BMGA 3BT2A 1P0SL 2BOKL 1EPJA 1WHEA 2P3FL 3K9XA 2WPKE 1HRFA 2UWLB 1LMJA 2BO2A 3ZYIB 2HORA 3SOVA 2W2OE 2P26A 2XBVL 4MMXB 2B7DL 2XC0L 2BT8A 3KQDL 3TGFA 5CISA 1NFWB 3ASIA 3IITB 1HT5A 5IKTA 2OYEP 2BOUA 4RRWA 3V64C 3M36L 4ZXYL 1G1TA 3GCWE 4GU3A 2YGPA 1HCGB 1XKAL 4BXWA 2K2TA 1G2MB 4G1MB 3POYA 3LN0A 3NTGA 1NPEB 1EBVA 3RR3A 4TGFA 2XC4L 1PGEA 1APOA 1IOXA 1C5MF 1I0UA 1IQNL 2VH0B 5IKVA 2BZ6L 4COXA 3QCWA 1IQML 1FAKL 1V3XB 4Y7AB 1XFEA 2VVUL 5JBAE 2VVVL 1EPIA 1CCFA 1Z6CA 3CENL 1IGXA 1L3YA 2DDUA 4BXSA 2FLGA 2YGOA 3TK6B 1FJSL 2W86A 3NTBA 2H9EL 4Z6AL 1CVWL 3S6XA 4BTTA 4YT6L 2Y81B 1APQA 1IQKL 2W26B 4PH9A 2VWMK 4D0FA 1DDXA 1G2LB 1KLIL 1DX5I 1JL9A 3Q7DA 2VH6B 3MDLA 3N8WB 4A7IA 1IP0A 1YGCL 2I9AA 3N8XA 4CUEA 2BQ6A 3LC5B 2RHPA 2WPHE 1JV2B 2XC5L 1IQLL 1WHFA 2P28B 1KKEA 4JYVL 2K2SB 1HT8A 1IQGL 2BT7A 1FAXL 1F0RB 2Y5FL 3DEMA 4M11A 4MMZB 4MMYB 1KSNB 4RRZA 4JYUL 2WFTA 4Y7BB 1WU1B 1NFUB 2Y5HL 5L2YL 1O5DL 3V65B 5F1AA 1CCVA 2RA0L 3KRKA 2W2PE 1URKA 1OB1C 4D0EA 2TGFA 3F6UL 1MQ5L 1NQLB 3EGFA 3OLUA 1IGZA 3U73A 1DIYA 2P3TA 4JZDL 1FF7A 5IKRA 1K36A 2MHPA 1EMNA 1V1HA 2WYJB 3HO3A 2PR3B 3MQEA 3QH0A 2P93L 4RUTA 1EGFA 1F0SB 3PGHA 3OLTA 4C16A 5KN5C 1KLOA 4BTUA 2JKHL 2P95L 2Y38A 1IQHL 6COXA 4Y6DB 2PHBB 1HAEA 4X8SL 3CS7L 1J9CL 2UWPB 2BOXA 5E8DA 2MGPA 1UZQA 4LORA 3BPSE 1IQFL 2VJ3A 1EMOA 1IQJL 1NZIA 4GU4A 4X8UL 4YT7L 1KIGL 4JZFL 4ISHL 1YUKB 1K37A 4YZUB 3N8VA 1HX2A 5JVZA 3SW2A 2OYUP 1CEJA 1GK5A 5CKNA 1X7AL 2BQ7A 4BDWA 3CFWA 1QFKL 3F1SB 5K0HB 1EPGA 2FLBL 2WPME 4Y71B 4O02B 2WG4B 3LN1A 1TLEA 4JZEL 4RRYA 2WPJE 4Y79B 1P9JA 1ATDA 5FDQA 2VVCK 2XBXL 4CUFA 2Y7XB 5JB8E 5JVYA 5KIRA 3TZIA 1DVAL 1CX2A 4OTJA 3KQBL 2H9EC 1MQ6L 1EPHA 1G1QA 1IJQA 4XLWA 3N8YA 1UZPA 2HOXA 1JBUL 3TH3L 4NA9L 2BSFA 1NFYB 2FZZL 2GD4A 3FFGL 2FD6A 2Q1JB 5JB9E 5F19A 4CSYA 4Y76B 1EZQB 1TOZA 1NT0A 3TBDA 4NG9L 3ELAL 4ZHAB 2WZPP 2EI8B 5JBBE 1FSBA 2W3IB 3ZYGA 1AUTL 5EGMB 1QIUA 3KCGL 4ZXXL 1N1IA 1U67A 2J94B 1XDTR 2EI7B 4XL1A 2YGQA 1LMMA 2VRSA 3N8YB 1HJ7A 5L2ZL 2KL7A 3M37L 1PRHA 1HREA 3LAQA 1F7EA 5JBCE 2VWLL 1KLJL 3FCSB 3KK6A 3LTFB 2J2UB 4OTYA 2I9BA 2VWOL 1FFMA 3N8ZA 2W2ME 2UWOB 1ADXA 2XBYL 4ZAEB 2P16L 2M74A 5CKMA 3Q3KB 1LK9A 2W3KB 1IOEL 3KQEL 1PTHA 1TPGA 1PXXA 1U8CB 2CJIB 1A3PA 1G1RA 2ADXA 2W2QE 1RFNB 5L30L 1YUFA 1ATBA 2FLRL 3NJPC 3TK5B 4X8VL 3HO4A 4BTIA 1BF9A 4A94C 1Z6EL 4Z0KB 2Y80B 3SOQA 1ZAQA 1NFXB 2WPIE 5I46L 1G1SA 4Z0LA 1ATEA 3HO5A 3ZYJB 5JW1A 3HS5A 2J95B 3HS6A 4NGAL 2AYLA 4BDXA 2MGRA 1ATAA 4E1GA 1UZKA 2Y82B 2NPRA 3LC3B 3R05A 4RRXA 1YUGA 4D90A 2WYGB 2JJLA 2F9BL 3N8WA 4RS0A 3LIWB 1SZBA 2WPLE 2RNLA 3BT1A
chains in the Genus database with same CATH topology
3CA7A 1N7DA 1IVOC 1HZ8A 1LPGA 1FE2A 4XBMA 4LMFA 1L5GB 3NT1A 2KV4A 4AQTA 1Q4GA 5CKQA 2P94L 4X8TL 1UZJA 3GISX 2Y5GL 3SOBB 1CVUA 1EQHA 3H5CB 3IJEB 2J34B 5IKQA 3HPTA 4O1ZA 2D1JB 2VWNL 4CUDA 2BQWA 4ISIL 3P5BL 1IQEL 3ENSA 2WG3C 2XBWL 3LTGD 1MOXC 2G00L 2KNIA 1LPKA 4ZH8B 3GCXE 1M1XB 2WFXB 1LQDA 3QMOA 2PUQL 2Y7ZB 1DQBA 2KB9A 3KQCL 1IQIL 2J4IB 2P3FN 1COUA 3C9AC 1W7XL 2W2NE 1B9WA 3HS7A 1HAFA 2EI6B 1F7MA 2BOHA 2P3UA 1W8BL 1EQGA 3U7UG 1PFXL 1EAIC 3FBYA 1LPZA 4M10A 4FM5A 1CQEA 3KL6B 1XKBA 1YO8A 2J38B 5COXA 2BMGA 3BT2A 1P0SL 2BOKL 1EPJA 1WHEA 2P3FL 3K9XA 2WPKE 1HRFA 2UWLB 1LMJA 2BO2A 3ZYIB 3SOVA 2W2OE 2P26A 2XBVL 4MMXB 2B7DL 2XC0L 3KQDL 3TGFA 5CISA 1NFWB 3ASIA 3IITB 1HT5A 5IKTA 2OYEP 2BOUA 4RRWA 3V64C 3M36L 4ZXYL 1G1TA 3GCWE 2YGPA 1HCGB 1XKAL 4BXWA 2K2TA 1G2MB 4G1MB 3POYA 3LN0A 3NTGA 1NPEB 1EBVA 3RR3A 4TGFA 2XC4L 1PGEA 1APOA 1IOXA 1C5MF 1I0UA 1IQNL 2VH0B 5IKVA 2BZ6L 4COXA 3QCWA 1IQML 1FAKL 1V3XB 4Y7AB 1XFEA 2VVUL 5JBAE 2VVVL 1EPIA 1CCFA 1Z6CA 3CENL 1IGXA 1L3YA 2DDUA 4BXSA 2FLGA 2YGOA 3TK6B 1FJSL 2W86A 3NTBA 2H9EL 4Z6AL 1CVWL 3S6XA 4BTTA 4YT6L 2Y81B 1APQA 1IQKL 2W26B 4PH9A 2VWMK 4D0FA 1DDXA 1G2LB 1KLIL 1DX5I 1JL9A 3Q7DA 2VH6B 3MDLA 3N8WB 4A7IA 1IP0A 1YGCL 2I9AA 3N8XA 4CUEA 2BQ6A 3LC5B 2RHPA 2WPHE 1JV2B 2XC5L 1IQLL 1WHFA 2P28B 4JYVL 2K2SB 1HT8A 1IQGL 1FAXL 1F0RB 2Y5FL 3DEMA 4M11A 4MMZB 4MMYB 1KSNB 4RRZA 4JYUL 2WFTA 4Y7BB 1WU1B 1NFUB 2Y5HL 5L2YL 1O5DL 3V65B 5F1AA 1CCVA 2RA0L 3KRKA 2W2PE 1URKA 1OB1C 4D0EA 2TGFA 3F6UL 1MQ5L 1NQLB 3EGFA 3OLUA 1IGZA 3U73A 1DIYA 2P3TA 4JZDL 1FF7A 5IKRA 1K36A 2MHPA 1EMNA 2WYJB 3HO3A 2PR3B 3MQEA 3QH0A 2P93L 4RUTA 1EGFA 1F0SB 3PGHA 3OLTA 4C16A 5KN5C 1KLOA 4BTUA 2JKHL 2P95L 2Y38A 1IQHL 6COXA 4Y6DB 2PHBB 1HAEA 4X8SL 3CS7L 1J9CL 2UWPB 2BOXA 5E8DA 2MGPA 1UZQA 4LORA 3BPSE 1IQFL 2VJ3A 1EMOA 1IQJL 1NZIA 4X8UL 4YT7L 1KIGL 4JZFL 4ISHL 1YUKB 1K37A 4YZUB 3N8VA 1HX2A 5JVZA 3SW2A 2OYUP 1CEJA 1GK5A 5CKNA 1X7AL 2BQ7A 4BDWA 3CFWA 1QFKL 3F1SB 5K0HB 1EPGA 2FLBL 2WPME 4Y71B 4O02B 2WG4B 3LN1A 1TLEA 4JZEL 4RRYA 2WPJE 4Y79B 1P9JA 1ATDA 5FDQA 2VVCK 2XBXL 4CUFA 2Y7XB 5JB8E 5JVYA 5KIRA 3TZIA 1DVAL 1CX2A 4OTJA 3KQBL 2H9EC 1MQ6L 1EPHA 1G1QA 1IJQA 4XLWA 3N8YA 1UZPA 1JBUL 3TH3L 4NA9L 1NFYB 2FZZL 2GD4A 3FFGL 2FD6A 2Q1JB 5JB9E 5F19A 4CSYA 4Y76B 1EZQB 1TOZA 1NT0A 3TBDA 4NG9L 3ELAL 4ZHAB 2WZPP 2EI8B 5JBBE 1FSBA 2W3IB 3ZYGA 1AUTL 5EGMB 3KCGL 4ZXXL 1N1IA 1U67A 2J94B 1XDTR 2EI7B 4XL1A 2YGQA 1LMMA 3N8YB 1HJ7A 5L2ZL 2KL7A 3M37L 1PRHA 1HREA 3LAQA 1F7EA 5JBCE 2VWLL 1KLJL 3FCSB 3KK6A 3LTFB 2J2UB 4OTYA 2I9BA 2VWOL 1FFMA 3N8ZA 2W2ME 2UWOB 1ADXA 2XBYL 4ZAEB 2P16L 2M74A 5CKMA 3Q3KB 2W3KB 1IOEL 3KQEL 1PTHA 1TPGA 1PXXA 1U8CB 2CJIB 1A3PA 1G1RA 2ADXA 2W2QE 1RFNB 5L30L 1YUFA 1ATBA 2FLRL 3NJPC 3TK5B 4X8VL 3HO4A 4BTIA 1BF9A 4A94C 1Z6EL 4Z0KB 2Y80B 3SOQA 1ZAQA 1NFXB 2WPIE 5I46L 1G1SA 4Z0LA 1ATEA 3HO5A 3ZYJB 5JW1A 3HS5A 2J95B 3HS6A 4NGAL 2AYLA 4BDXA 2MGRA 1ATAA 4E1GA 1UZKA 2Y82B 2NPRA 3LC3B 3R05A 4RRXA 1YUGA 4D90A 2WYGB 2F9BL 3N8WA 4RS0A 3LIWB 1SZBA 2WPLE 2RNLA 3BT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CA7 A;  1N7D A;  1IVO C;  1HZ8 A;  1LPG A;  1FE2 A;  4XBM A;  4LMF A;  1L5G B;  3NT1 A;  2KV4 A;  4AQT A;  1Q4G A;  5CKQ A;  2P94 L;  4X8T L;  1UZJ A;  3GIS X;  2Y5G L;  3SOB B;  1CVU A;  1EQH A;  3H5C B;  3IJE B;  2J34 B;  5IKQ A;  3HPT A;  4O1Z A;  2D1J B;  2VWN L;  4CUD A;  2BQW A;  4ISI L;  3P5B L;  1IQE L;  3ENS A;  2WG3 C;  2XBW L;  3LTG D;  1MOX C;  2G00 L;  1LPK A;  4ZH8 B;  3GCX E;  1M1X B;  2WFX B;  1LQD A;  3QMO A;  2PUQ L;  2Y7Z B;  1DQB A;  2KB9 A;  3KQC L;  1IQI L;  2J4I B;  2P3F N;  1COU A;  3C9A C;  1W7X L;  2W2N E;  1B9W A;  3HS7 A;  1HAF A;  2EI6 B;  1F7M A;  2BOH A;  2P3U A;  1W8B L;  1EQG A;  3U7U G;  1PFX L;  1EAI C;  3FBY A;  1LPZ A;  4M10 A;  4FM5 A;  1CQE A;  3KL6 B;  1XKB A;  1YO8 A;  2J38 B;  5COX A;  2BMG A;  3BT2 A;  1P0S L;  2BOK L;  1EPJ A;  1WHE A;  2P3F L;  3K9X A;  2WPK E;  1HRF A;  2UWL B;  1LMJ A;  2BO2 A;  3ZYI B;  3SOV A;  2W2O E;  2P26 A;  2XBV L;  4MMX B;  2B7D L;  2XC0 L;  3KQD L;  3TGF A;  5CIS A;  1NFW B;  3ASI A;  3IIT B;  1HT5 A;  5IKT A;  2OYE P;  2BOU A;  4RRW A;  3V64 C;  3M36 L;  4ZXY L;  1G1T A;  3GCW E;  2YGP A;  1HCG B;  1XKA L;  4BXW A;  2K2T A;  1G2M B;  4G1M B;  3POY A;  3LN0 A;  3NTG A;  1NPE B;  1EBV A;  3RR3 A;  4TGF A;  2XC4 L;  1PGE A;  1APO A;  1IOX A;  1C5M F;  1I0U A;  1IQN L;  2VH0 B;  5IKV A;  2BZ6 L;  4COX A;  3QCW A;  1IQM L;  1FAK L;  1V3X B;  4Y7A B;  1XFE A;  2VVU L;  5JBA E;  2VVV L;  1EPI A;  1CCF A;  1Z6C A;  3CEN L;  1IGX A;  1L3Y A;  2DDU A;  4BXS A;  2FLG A;  2YGO A;  3TK6 B;  1FJS L;  2W86 A;  3NTB A;  2H9E L;  4Z6A L;  1CVW L;  4BTT A;  4YT6 L;  2Y81 B;  1APQ A;  1IQK L;  2W26 B;  4PH9 A;  2VWM K;  4D0F A;  1DDX A;  1G2L B;  1KLI L;  1DX5 I;  1JL9 A;  3Q7D A;  2VH6 B;  3MDL A;  3N8W B;  4A7I A;  1IP0 A;  1YGC L;  2I9A A;  3N8X A;  4CUE A;  2BQ6 A;  3LC5 B;  2RHP A;  2WPH E;  1JV2 B;  2XC5 L;  1IQL L;  1WHF A;  2P28 B;  4JYV L;  2K2S B;  1HT8 A;  1IQG L;  1FAX L;  1F0R B;  2Y5F L;  3DEM A;  4M11 A;  4MMZ B;  4MMY B;  1KSN B;  4RRZ A;  4JYU L;  2WFT A;  4Y7B B;  1WU1 B;  1NFU B;  2Y5H L;  5L2Y L;  1O5D L;  3V65 B;  5F1A A;  1CCV A;  2RA0 L;  3KRK A;  2W2P E;  1URK A;  1OB1 C;  4D0E A;  2TGF A;  3F6U L;  1MQ5 L;  1NQL B;  3EGF A;  3OLU A;  1IGZ A;  3U73 A;  1DIY A;  2P3T A;  4JZD L;  1FF7 A;  5IKR A;  1K36 A;  2MHP A;  1EMN A;  2WYJ B;  3HO3 A;  2PR3 B;  3MQE A;  3QH0 A;  2P93 L;  4RUT A;  1EGF A;  1F0S B;  3PGH A;  3OLT A;  4C16 A;  5KN5 C;  1KLO A;  4BTU A;  2JKH L;  2P95 L;  2Y38 A;  1IQH L;  6COX A;  4Y6D B;  2PHB B;  1HAE A;  4X8S L;  3CS7 L;  1J9C L;  2UWP B;  2BOX A;  5E8D A;  2MGP A;  1UZQ A;  4LOR A;  3BPS E;  1IQF L;  2VJ3 A;  1EMO A;  1IQJ L;  1NZI A;  4X8U L;  4YT7 L;  1KIG L;  4JZF L;  4ISH L;  1YUK B;  1K37 A;  4YZU B;  3N8V A;  1HX2 A;  5JVZ A;  3SW2 A;  2OYU P;  1CEJ A;  1GK5 A;  5CKN A;  1X7A L;  2BQ7 A;  4BDW A;  3CFW A;  1QFK L;  3F1S B;  5K0H B;  1EPG A;  2FLB L;  2WPM E;  4Y71 B;  4O02 B;  2WG4 B;  3LN1 A;  1TLE A;  4JZE L;  4RRY A;  2WPJ E;  4Y79 B;  1P9J A;  1ATD A;  5FDQ A;  2VVC K;  2XBX L;  4CUF A;  2Y7X B;  5JB8 E;  5JVY A;  5KIR A;  3TZI A;  1DVA L;  1CX2 A;  4OTJ A;  3KQB L;  1MQ6 L;  1EPH A;  1G1Q A;  1IJQ A;  4XLW A;  3N8Y A;  1UZP A;  1JBU L;  3TH3 L;  4NA9 L;  1NFY B;  2FZZ L;  2GD4 A;  3FFG L;  2FD6 A;  2Q1J B;  5JB9 E;  5F19 A;  4CSY A;  4Y76 B;  1EZQ B;  1TOZ A;  1NT0 A;  3TBD A;  4NG9 L;  3ELA L;  4ZHA B;  2EI8 B;  5JBB E;  1FSB A;  2W3I B;  3ZYG A;  1AUT L;  5EGM B;  3KCG L;  4ZXX L;  1N1I A;  1U67 A;  2J94 B;  1XDT R;  2EI7 B;  4XL1 A;  3N8Y B;  1HJ7 A;  5L2Z L;  2KL7 A;  3M37 L;  1PRH A;  1HRE A;  3LAQ A;  1F7E A;  5JBC E;  2VWL L;  1KLJ L;  3FCS B;  3KK6 A;  3LTF B;  2J2U B;  4OTY A;  2I9B A;  2VWO L;  1FFM A;  3N8Z A;  2W2M E;  2UWO B;  1ADX A;  2XBY L;  4ZAE B;  2P16 L;  2M74 A;  5CKM A;  3Q3K B;  2W3K B;  1IOE L;  3KQE L;  1PTH A;  1TPG A;  1PXX A;  1U8C B;  2CJI B;  1A3P A;  1G1R A;  2ADX A;  2W2Q E;  1RFN B;  5L30 L;  1YUF A;  1ATB A;  2FLR L;  3NJP C;  3TK5 B;  4X8V L;  3HO4 A;  4BTI A;  1BF9 A;  1Z6E L;  4Z0K B;  2Y80 B;  3SOQ A;  1ZAQ A;  1NFX B;  2WPI E;  5I46 L;  1G1S A;  4Z0L A;  1ATE A;  3HO5 A;  3ZYJ B;  5JW1 A;  3HS5 A;  2J95 B;  3HS6 A;  4NGA L;  2AYL A;  4BDX A;  2MGR A;  1ATA A;  4E1G A;  1UZK A;  2Y82 B;  2NPR A;  3LC3 B;  3R05 A;  4RRX A;  1YUG A;  4D90 A;  2WYG B;  2F9B L;  3N8W A;  4RS0 A;  3LIW B;  1SZB A;  2WPL E;  2RNL A;  3BT1 A; 
#chains in the Genus database with same CATH topology
 3CA7 A;  1N7D A;  1IVO C;  1HZ8 A;  1LPG A;  1FE2 A;  4XBM A;  4LMF A;  1L5G B;  3NT1 A;  2KV4 A;  4AQT A;  1Q4G A;  5CKQ A;  2P94 L;  4X8T L;  1UZJ A;  3GIS X;  2Y5G L;  3SOB B;  1CVU A;  1EQH A;  3H5C B;  3IJE B;  2J34 B;  5IKQ A;  3HPT A;  4O1Z A;  2D1J B;  2VWN L;  4CUD A;  2BQW A;  4ISI L;  3P5B L;  1IQE L;  3ENS A;  2WG3 C;  2XBW L;  3LTG D;  1MOX C;  2G00 L;  2KNI A;  1LPK A;  4ZH8 B;  3GCX E;  1M1X B;  2WFX B;  1LQD A;  3QMO A;  2PUQ L;  2Y7Z B;  1DQB A;  2KB9 A;  3KQC L;  1V1I A;  1IQI L;  2J4I B;  2P3F N;  1COU A;  3C9A C;  1W7X L;  2W2N E;  1B9W A;  3HS7 A;  1HAF A;  2EI6 B;  1F7M A;  2BOH A;  2P3U A;  1W8B L;  1EQG A;  3U7U G;  1PFX L;  1EAI C;  3FBY A;  1LPZ A;  4M10 A;  4FM5 A;  1CQE A;  3KL6 B;  1XKB A;  1YO8 A;  2J38 B;  5COX A;  2BMG A;  3BT2 A;  1P0S L;  2BOK L;  1EPJ A;  1WHE A;  2P3F L;  3K9X A;  2WPK E;  1HRF A;  2UWL B;  1LMJ A;  2BO2 A;  3ZYI B;  2HOR A;  3SOV A;  2W2O E;  2P26 A;  2XBV L;  4MMX B;  2B7D L;  2XC0 L;  2BT8 A;  3KQD L;  3TGF A;  5CIS A;  1NFW B;  3ASI A;  3IIT B;  1HT5 A;  5IKT A;  2OYE P;  2BOU A;  4RRW A;  3V64 C;  3M36 L;  4ZXY L;  1G1T A;  3GCW E;  4GU3 A;  2YGP A;  1HCG B;  1XKA L;  4BXW A;  2K2T A;  1G2M B;  4G1M B;  3POY A;  3LN0 A;  3NTG A;  1NPE B;  1EBV A;  3RR3 A;  4TGF A;  2XC4 L;  1PGE A;  1APO A;  1IOX A;  1C5M F;  1I0U A;  1IQN L;  2VH0 B;  5IKV A;  2BZ6 L;  4COX A;  3QCW A;  1IQM L;  1FAK L;  1V3X B;  4Y7A B;  1XFE A;  2VVU L;  5JBA E;  2VVV L;  1EPI A;  1CCF A;  1Z6C A;  3CEN L;  1IGX A;  1L3Y A;  2DDU A;  4BXS A;  2FLG A;  2YGO A;  3TK6 B;  1FJS L;  2W86 A;  3NTB A;  2H9E L;  4Z6A L;  1CVW L;  3S6X A;  4BTT A;  4YT6 L;  2Y81 B;  1APQ A;  1IQK L;  2W26 B;  4PH9 A;  2VWM K;  4D0F A;  1DDX A;  1G2L B;  1KLI L;  1DX5 I;  1JL9 A;  3Q7D A;  2VH6 B;  3MDL A;  3N8W B;  4A7I A;  1IP0 A;  1YGC L;  2I9A A;  3N8X A;  4CUE A;  2BQ6 A;  3LC5 B;  2RHP A;  2WPH E;  1JV2 B;  2XC5 L;  1IQL L;  1WHF A;  2P28 B;  1KKE A;  4JYV L;  2K2S B;  1HT8 A;  1IQG L;  2BT7 A;  1FAX L;  1F0R B;  2Y5F L;  3DEM A;  4M11 A;  4MMZ B;  4MMY B;  1KSN B;  4RRZ A;  4JYU L;  2WFT A;  4Y7B B;  1WU1 B;  1NFU B;  2Y5H L;  5L2Y L;  1O5D L;  3V65 B;  5F1A A;  1CCV A;  2RA0 L;  3KRK A;  2W2P E;  1URK A;  1OB1 C;  4D0E A;  2TGF A;  3F6U L;  1MQ5 L;  1NQL B;  3EGF A;  3OLU A;  1IGZ A;  3U73 A;  1DIY A;  2P3T A;  4JZD L;  1FF7 A;  5IKR A;  1K36 A;  2MHP A;  1EMN A;  1V1H A;  2WYJ B;  3HO3 A;  2PR3 B;  3MQE A;  3QH0 A;  2P93 L;  4RUT A;  1EGF A;  1F0S B;  3PGH A;  3OLT A;  4C16 A;  5KN5 C;  1KLO A;  4BTU A;  2JKH L;  2P95 L;  2Y38 A;  1IQH L;  6COX A;  4Y6D B;  2PHB B;  1HAE A;  4X8S L;  3CS7 L;  1J9C L;  2UWP B;  2BOX A;  5E8D A;  2MGP A;  1UZQ A;  4LOR A;  3BPS E;  1IQF L;  2VJ3 A;  1EMO A;  1IQJ L;  1NZI A;  4GU4 A;  4X8U L;  4YT7 L;  1KIG L;  4JZF L;  4ISH L;  1YUK B;  1K37 A;  4YZU B;  3N8V A;  1HX2 A;  5JVZ A;  3SW2 A;  2OYU P;  1CEJ A;  1GK5 A;  5CKN A;  1X7A L;  2BQ7 A;  4BDW A;  3CFW A;  1QFK L;  3F1S B;  5K0H B;  1EPG A;  2FLB L;  2WPM E;  4Y71 B;  4O02 B;  2WG4 B;  3LN1 A;  1TLE A;  4JZE L;  4RRY A;  2WPJ E;  4Y79 B;  1P9J A;  1ATD A;  5FDQ A;  2VVC K;  2XBX L;  4CUF A;  2Y7X B;  5JB8 E;  5JVY A;  5KIR A;  3TZI A;  1DVA L;  1CX2 A;  4OTJ A;  3KQB L;  2H9E C;  1MQ6 L;  1EPH A;  1G1Q A;  1IJQ A;  4XLW A;  3N8Y A;  1UZP A;  2HOX A;  1JBU L;  3TH3 L;  4NA9 L;  2BSF A;  1NFY B;  2FZZ L;  2GD4 A;  3FFG L;  2FD6 A;  2Q1J B;  5JB9 E;  5F19 A;  4CSY A;  4Y76 B;  1EZQ B;  1TOZ A;  1NT0 A;  3TBD A;  4NG9 L;  3ELA L;  4ZHA B;  2WZP P;  2EI8 B;  5JBB E;  1FSB A;  2W3I B;  3ZYG A;  1AUT L;  5EGM B;  1QIU A;  3KCG L;  4ZXX L;  1N1I A;  1U67 A;  2J94 B;  1XDT R;  2EI7 B;  4XL1 A;  2YGQ A;  1LMM A;  2VRS A;  3N8Y B;  1HJ7 A;  5L2Z L;  2KL7 A;  3M37 L;  1PRH A;  1HRE A;  3LAQ A;  1F7E A;  5JBC E;  2VWL L;  1KLJ L;  3FCS B;  3KK6 A;  3LTF B;  2J2U B;  4OTY A;  2I9B A;  2VWO L;  1FFM A;  3N8Z A;  2W2M E;  2UWO B;  1ADX A;  2XBY L;  4ZAE B;  2P16 L;  2M74 A;  5CKM A;  3Q3K B;  1LK9 A;  2W3K B;  1IOE L;  3KQE L;  1PTH A;  1TPG A;  1PXX A;  1U8C B;  2CJI B;  1A3P A;  1G1R A;  2ADX A;  2W2Q E;  1RFN B;  5L30 L;  1YUF A;  1ATB A;  2FLR L;  3NJP C;  3TK5 B;  4X8V L;  3HO4 A;  4BTI A;  1BF9 A;  4A94 C;  1Z6E L;  4Z0K B;  2Y80 B;  3SOQ A;  1ZAQ A;  1NFX B;  2WPI E;  5I46 L;  1G1S A;  4Z0L A;  1ATE A;  3HO5 A;  3ZYJ B;  5JW1 A;  3HS5 A;  2J95 B;  3HS6 A;  4NGA L;  2AYL A;  4BDX A;  2MGR A;  1ATA A;  4E1G A;  1UZK A;  2Y82 B;  2NPR A;  3LC3 B;  3R05 A;  4RRX A;  1YUG A;  4D90 A;  2WYG B;  2JJL A;  2F9B L;  3N8W A;  4RS0 A;  3LIW B;  1SZB A;  2WPL E;  2RNL A;  3BT1 A; 
#chains in the Genus database with same CATH homology
 3CA7 A;  1N7D A;  1IVO C;  1HZ8 A;  1LPG A;  1FE2 A;  4XBM A;  4LMF A;  1L5G B;  3NT1 A;  2KV4 A;  4AQT A;  1Q4G A;  5CKQ A;  2P94 L;  4X8T L;  1UZJ A;  3GIS X;  2Y5G L;  3SOB B;  1CVU A;  1EQH A;  3H5C B;  3IJE B;  2J34 B;  5IKQ A;  3HPT A;  4O1Z A;  2D1J B;  2VWN L;  4CUD A;  2BQW A;  4ISI L;  3P5B L;  1IQE L;  3ENS A;  2WG3 C;  2XBW L;  3LTG D;  1MOX C;  2G00 L;  2KNI A;  1LPK A;  4ZH8 B;  3GCX E;  1M1X B;  2WFX B;  1LQD A;  3QMO A;  2PUQ L;  2Y7Z B;  1DQB A;  2KB9 A;  3KQC L;  1IQI L;  2J4I B;  2P3F N;  1COU A;  3C9A C;  1W7X L;  2W2N E;  1B9W A;  3HS7 A;  1HAF A;  2EI6 B;  1F7M A;  2BOH A;  2P3U A;  1W8B L;  1EQG A;  3U7U G;  1PFX L;  1EAI C;  3FBY A;  1LPZ A;  4M10 A;  4FM5 A;  1CQE A;  3KL6 B;  1XKB A;  1YO8 A;  2J38 B;  5COX A;  2BMG A;  3BT2 A;  1P0S L;  2BOK L;  1EPJ A;  1WHE A;  2P3F L;  3K9X A;  2WPK E;  1HRF A;  2UWL B;  1LMJ A;  2BO2 A;  3ZYI B;  3SOV A;  2W2O E;  2P26 A;  2XBV L;  4MMX B;  2B7D L;  2XC0 L;  3KQD L;  3TGF A;  5CIS A;  1NFW B;  3ASI A;  3IIT B;  1HT5 A;  5IKT A;  2OYE P;  2BOU A;  4RRW A;  3V64 C;  3M36 L;  4ZXY L;  1G1T A;  3GCW E;  2YGP A;  1HCG B;  1XKA L;  4BXW A;  2K2T A;  1G2M B;  4G1M B;  3POY A;  3LN0 A;  3NTG A;  1NPE B;  1EBV A;  3RR3 A;  4TGF A;  2XC4 L;  1PGE A;  1APO A;  1IOX A;  1C5M F;  1I0U A;  1IQN L;  2VH0 B;  5IKV A;  2BZ6 L;  4COX A;  3QCW A;  1IQM L;  1FAK L;  1V3X B;  4Y7A B;  1XFE A;  2VVU L;  5JBA E;  2VVV L;  1EPI A;  1CCF A;  1Z6C A;  3CEN L;  1IGX A;  1L3Y A;  2DDU A;  4BXS A;  2FLG A;  2YGO A;  3TK6 B;  1FJS L;  2W86 A;  3NTB A;  2H9E L;  4Z6A L;  1CVW L;  3S6X A;  4BTT A;  4YT6 L;  2Y81 B;  1APQ A;  1IQK L;  2W26 B;  4PH9 A;  2VWM K;  4D0F A;  1DDX A;  1G2L B;  1KLI L;  1DX5 I;  1JL9 A;  3Q7D A;  2VH6 B;  3MDL A;  3N8W B;  4A7I A;  1IP0 A;  1YGC L;  2I9A A;  3N8X A;  4CUE A;  2BQ6 A;  3LC5 B;  2RHP A;  2WPH E;  1JV2 B;  2XC5 L;  1IQL L;  1WHF A;  2P28 B;  4JYV L;  2K2S B;  1HT8 A;  1IQG L;  1FAX L;  1F0R B;  2Y5F L;  3DEM A;  4M11 A;  4MMZ B;  4MMY B;  1KSN B;  4RRZ A;  4JYU L;  2WFT A;  4Y7B B;  1WU1 B;  1NFU B;  2Y5H L;  5L2Y L;  1O5D L;  3V65 B;  5F1A A;  1CCV A;  2RA0 L;  3KRK A;  2W2P E;  1URK A;  1OB1 C;  4D0E A;  2TGF A;  3F6U L;  1MQ5 L;  1NQL B;  3EGF A;  3OLU A;  1IGZ A;  3U73 A;  1DIY A;  2P3T A;  4JZD L;  1FF7 A;  5IKR A;  1K36 A;  2MHP A;  1EMN A;  2WYJ B;  3HO3 A;  2PR3 B;  3MQE A;  3QH0 A;  2P93 L;  4RUT A;  1EGF A;  1F0S B;  3PGH A;  3OLT A;  4C16 A;  5KN5 C;  1KLO A;  4BTU A;  2JKH L;  2P95 L;  2Y38 A;  1IQH L;  6COX A;  4Y6D B;  2PHB B;  1HAE A;  4X8S L;  3CS7 L;  1J9C L;  2UWP B;  2BOX A;  5E8D A;  2MGP A;  1UZQ A;  4LOR A;  3BPS E;  1IQF L;  2VJ3 A;  1EMO A;  1IQJ L;  1NZI A;  4X8U L;  4YT7 L;  1KIG L;  4JZF L;  4ISH L;  1YUK B;  1K37 A;  4YZU B;  3N8V A;  1HX2 A;  5JVZ A;  3SW2 A;  2OYU P;  1CEJ A;  1GK5 A;  5CKN A;  1X7A L;  2BQ7 A;  4BDW A;  3CFW A;  1QFK L;  3F1S B;  5K0H B;  1EPG A;  2FLB L;  2WPM E;  4Y71 B;  4O02 B;  2WG4 B;  3LN1 A;  1TLE A;  4JZE L;  4RRY A;  2WPJ E;  4Y79 B;  1P9J A;  1ATD A;  5FDQ A;  2VVC K;  2XBX L;  4CUF A;  2Y7X B;  5JB8 E;  5JVY A;  5KIR A;  3TZI A;  1DVA L;  1CX2 A;  4OTJ A;  3KQB L;  2H9E C;  1MQ6 L;  1EPH A;  1G1Q A;  1IJQ A;  4XLW A;  3N8Y A;  1UZP A;  1JBU L;  3TH3 L;  4NA9 L;  1NFY B;  2FZZ L;  2GD4 A;  3FFG L;  2FD6 A;  2Q1J B;  5JB9 E;  5F19 A;  4CSY A;  4Y76 B;  1EZQ B;  1TOZ A;  1NT0 A;  3TBD A;  4NG9 L;  3ELA L;  4ZHA B;  2WZP P;  2EI8 B;  5JBB E;  1FSB A;  2W3I B;  3ZYG A;  1AUT L;  5EGM B;  3KCG L;  4ZXX L;  1N1I A;  1U67 A;  2J94 B;  1XDT R;  2EI7 B;  4XL1 A;  2YGQ A;  1LMM A;  3N8Y B;  1HJ7 A;  5L2Z L;  2KL7 A;  3M37 L;  1PRH A;  1HRE A;  3LAQ A;  1F7E A;  5JBC E;  2VWL L;  1KLJ L;  3FCS B;  3KK6 A;  3LTF B;  2J2U B;  4OTY A;  2I9B A;  2VWO L;  1FFM A;  3N8Z A;  2W2M E;  2UWO B;  1ADX A;  2XBY L;  4ZAE B;  2P16 L;  2M74 A;  5CKM A;  3Q3K B;  2W3K B;  1IOE L;  3KQE L;  1PTH A;  1TPG A;  1PXX A;  1U8C B;  2CJI B;  1A3P A;  1G1R A;  2ADX A;  2W2Q E;  1RFN B;  5L30 L;  1YUF A;  1ATB A;  2FLR L;  3NJP C;  3TK5 B;  4X8V L;  3HO4 A;  4BTI A;  1BF9 A;  4A94 C;  1Z6E L;  4Z0K B;  2Y80 B;  3SOQ A;  1ZAQ A;  1NFX B;  2WPI E;  5I46 L;  1G1S A;  4Z0L A;  1ATE A;  3HO5 A;  3ZYJ B;  5JW1 A;  3HS5 A;  2J95 B;  3HS6 A;  4NGA L;  2AYL A;  4BDX A;  2MGR A;  1ATA A;  4E1G A;  1UZK A;  2Y82 B;  2NPR A;  3LC3 B;  3R05 A;  4RRX A;  1YUG A;  4D90 A;  2WYG B;  2F9B L;  3N8W A;  4RS0 A;  3LIW B;  1SZB A;  2WPL E;  2RNL A;  3BT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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