2J4IB

Crystal structure of a human factor xa inhibitor complex
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure- and Property-Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Acyclic Alanyl Amides as P4 Motifs.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords COAGULATION FACTOR X
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2006-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00008 EGF EGF-like domain
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2j4iB00
3POYA 3CS7L 1KLIL 1Q4GA 4RRZA 1N7DA 3TZIA 2WPKE 2D1JB 1F7EA 1CQEA 2Y5HL 2W2OE 2EI7B 1WU1B 5JB9E 3QCWA 3HPTA 2YGPA 2P28B 3ZYJB 2RA0L 2WPLE 4Z6AL 4LMFA 1V3XB 4JZEL 2J34B 2AYLA 5JB8E 1F0SB 3LC3B 4CUEA 1X7AL 3SW2A 5JVZA 5CKNA 3N8VA 1IJQA 2XC5L 2OYEP 2XBYL 3HS5A 3ENSA 3N8WB 4TGFA 3KQCL 4Y7AB 2F9BL 2FLGA 2KB9A 1EPHA 1HCGB 2XBVL 4NG9L 4E1GA 4ISIL 1YUFA 2MGRA 2I9BA 4ISHL 1HX2A 1IQGL 1DIYA 1COUA 1IQML 4O1ZA 5L2YL 1Z6CA 2YGOA 2Y7ZB 2Y5FL 3ELAL 2WYGB 3TK6B 2W2NE 3TBDA 1CX2A 2WG3C 2BMGA 4JYVL 1EGFA 2BOHA 2MGPA 4Y7BB 2M74A 2W2ME 2ADXA 5IKVA 3ASIA 3LTGD 1F7MA 2B7DL 2XC0L 1IQJL 1IQIL 2UWPB 2I9AA 4CUFA 5CISA 1HT5A 1MQ6L 1IGXA 1FAXL 1U67A 2WPJE 1YO8A 4BDXA 1TLEA 4YT6L 1NFYB 4BTTA 1EPIA 2P93L 2XBWL 2KV4A 3N8WA 1YGCL 3V64C 1C5MF 3BT2A 3KRKA 1APQA 2PR3B 3HO3A 3KL6B 3GISX 4Y79B 2TGFA 1DQBA 3OLTA 1MOXC 1GK5A 1XDTR 1EPGA 2DDUA 5IKTA 2FLBL 1EZQB 2J95B 4X8VL 1Z6EL 2W86A 1G2LB 2BQ6A 5JBBE 1UZKA 2BO2A 2WG4B 2VWMK 3ZYIB 3NTGA 5I46L 3MQEA 1APOA 3N8ZA 3H5CB 1CCFA 1FAKL 1IQNL 3ZYGA 2VH6B 3N8XA 2UWLB 4BTUA 1EPJA 3IJEB 1LQDA 4JYUL 1NFXB 1G1TA 4X8TL 2UWOB 2FD6A 1P0SL 3U73A 4C16A 2J38B 5EGMB 1NT0A 2PHBB 1PRHA 4RUTA 1CVUA 1P9JA 4JZDL 1ATBA 4X8SL 4NA9L 5K0HB 4MMZB 5L2ZL 3QMOA 1LPGA 1EAIC 3Q7DA 3K9XA 2PUQL 1NQLB 3Q3KB 2BQ7A 4RRYA 3C9AC 3MDLA 5E8DA 3KQEL 2GD4A 4XLWA 1WHFA 4Z0KB 2Y7XB 1HJ7A 4PH9A 1HREA 4D0FA 2WPHE 1ADXA 1XKAL 2W3KB 5CKQA 1HAFA 1A3PA 3TK5B 2RNLA 3R05A 2P3TA 3GCXE 4X8UL 1FE2A 3U7UG 2VJ3A 1KLJL 2W3IB 3LIWB 1FJSL 2VVVL 5CKMA 3FBYA 3SOQA 1FFMA 4NGAL 1QFKL 1JL9A 5JBCE 4D90A 1DX5I 1HRFA 4XL1A 3FFGL 1NZIA 1G1QA 2FLRL 2WFXB 1RFNB 1K36A 1L3YA 1M1XB 4M10A 5JW1A 2JKHL 2XC4L 1G1SA 2WPIE 2VVUL 2P95L 3N8YB 3KQDL 2VVCK 1WHEA 3NTBA 1FF7A 3HS7A 3CA7A 4BXWA 4Y76B 1YUGA 3RR3A 3SOBB 1LPKA 2OYUP 3BT1A 2NPRA 1I0UA 3KK6A 2BOKL 5IKQA 1JV2B 5F1AA 3BPSE 2P26A 4M11A 1AUTL 2Y80B 3TGFA 1W7XL 1B9WA 3CFWA 4RS0A 1NPEB 6COXA 4ZH8B 3SOVA 1CEJA 4RRWA 4FM5A 3V65B 2XBXL 1EQGA 3TH3L 3PGHA 1ATDA 2W26B 1LMJA 3CENL 4Y6DB 5KN5C 2FZZL 2Y38A 1HAEA 2Y81B 2BQWA 3IITB 3P5BL 1G2MB 1HZ8A 3NJPC 1PFXL 2P3FL 4CUDA 4Z0LA 1JBUL 4JZFL 1IP0A 4LORA 1EMNA 4ZAEB 1HT8A 3N8YA 4OTYA 2RHPA 1IVOC 4COXA 1CCVA 1IQFL 4XBMA 4CSYA 4RRXA 1KIGL 1G1RA 3LN0A 2W2PE 2VWNL 1LPZA 4AQTA 1IOEL 3OLUA 3DEMA 1IQLL 3LN1A 2J4IB 2VH0B 4BTIA 1UZJA 2K2TA 2WFTA 3HS6A 2VWOL 1DDXA 1IOXA 1PXXA 1SZBA 1PTHA 1TOZA 2BOXA 3HO4A 3F6UL 1ATAA 5IKRA 5JVYA 1J9CL 3LAQA 5KIRA 5FDQA 2K2SB 5F19A 1CVWL 3GCWE 4MMXB 2Y82B 1EQHA 1MQ5L 3LTFB 2BZ6L 1IQHL 1DVAL 3NT1A 4MMYB 2WPME 1L5GB 3LC5B 5COXA 4BXSA 1KLOA 1XKBA 1IQKL 1URKA 1KSNB 3KCGL 1BF9A 1EBVA 1O5DL 4OTJA 4O02B 1ATEA 2Y5GL 1W8BL 4D0EA 5L30L 3M36L 2Q1JB 2EI8B 4G1MB 2P3UA 2J94B 2H9EL 2J2UB 2VWLL 4Y71B 1TPGA 2BOUA 3M37L 2KL7A 4ZHAB 1NFUB 1N1IA 5JBAE 4YT7L 2P94L 1U8CB 1F0RB 1UZPA 4ZXXL 2P3FN 2CJIB 1IQEL 1K37A 2WYJB 1EMOA 2EI6B 4A7IA 1FSBA 1OB1C 1PGEA 3FCSB 2G00L 3HO5A 3QH0A 3EGFA 3KQBL 1XFEA 1ZAQA 1IGZA 2W2QE 4ZXYL 1NFWB 2MHPA 4YZUB 2P16L 3F1SB 1UZQA 4BDWA 1YUKB
chains in the Genus database with same CATH superfamily
3POYA 1V1IA 3CS7L 1KLIL 1Q4GA 4RRZA 1N7DA 3TZIA 2WPKE 2D1JB 1F7EA 4GU4A 1CQEA 2Y5HL 2W2OE 2EI7B 1WU1B 5JB9E 3QCWA 3HPTA 2YGPA 2P28B 3ZYJB 2RA0L 2WPLE 4Z6AL 4LMFA 1V3XB 4JZEL 2J34B 2AYLA 5JB8E 1F0SB 3LC3B 4CUEA 1X7AL 3SW2A 5JVZA 5CKNA 3N8VA 1IJQA 2XC5L 2OYEP 2XBYL 3HS5A 3ENSA 3N8WB 4TGFA 3KQCL 4Y7AB 4GU3A 2F9BL 2FLGA 2KB9A 1EPHA 1HCGB 2XBVL 4NG9L 4E1GA 4ISIL 1YUFA 2MGRA 2I9BA 4ISHL 1HX2A 1IQGL 1DIYA 1COUA 1IQML 4O1ZA 5L2YL 1Z6CA 2YGOA 2Y7ZB 2Y5FL 3ELAL 2WYGB 3TK6B 2W2NE 3TBDA 1CX2A 2WG3C 2HOXA 2BMGA 4JYVL 1EGFA 2BOHA 2MGPA 4Y7BB 2M74A 2W2ME 2ADXA 5IKVA 3ASIA 3LTGD 1F7MA 2HORA 2B7DL 2XC0L 1IQJL 1IQIL 2UWPB 2I9AA 4CUFA 5CISA 1KKEA 1HT5A 1MQ6L 1IGXA 1FAXL 1U67A 2WPJE 1YO8A 4BDXA 1TLEA 4YT6L 1NFYB 4BTTA 1EPIA 2P93L 2XBWL 2KV4A 3N8WA 1YGCL 3V64C 1C5MF 3BT2A 2BSFA 3KRKA 1APQA 2PR3B 3HO3A 3KL6B 3GISX 4Y79B 2TGFA 1DQBA 3OLTA 1MOXC 1GK5A 1XDTR 1EPGA 2DDUA 5IKTA 2FLBL 2JJLA 1EZQB 2J95B 4X8VL 1Z6EL 2W86A 1G2LB 2BQ6A 5JBBE 1UZKA 2BO2A 2WG4B 2VWMK 3ZYIB 3NTGA 5I46L 3MQEA 1APOA 3N8ZA 3H5CB 1CCFA 1FAKL 1IQNL 3ZYGA 2VH6B 3N8XA 2UWLB 4BTUA 1EPJA 3IJEB 1LQDA 4JYUL 1NFXB 1G1TA 4X8TL 2UWOB 2FD6A 1P0SL 3U73A 4C16A 2J38B 5EGMB 1NT0A 2PHBB 1PRHA 4RUTA 1CVUA 1P9JA 4JZDL 1ATBA 4X8SL 4NA9L 5K0HB 4MMZB 5L2ZL 3QMOA 1LPGA 1EAIC 3Q7DA 3K9XA 2PUQL 1NQLB 3Q3KB 2BQ7A 4RRYA 3C9AC 3MDLA 5E8DA 3KQEL 2GD4A 4XLWA 1WHFA 4Z0KB 2Y7XB 1HJ7A 4PH9A 1HREA 4D0FA 2WPHE 1ADXA 1XKAL 2W3KB 5CKQA 1HAFA 1A3PA 3TK5B 2RNLA 3R05A 2P3TA 2H9EC 3GCXE 4X8UL 1FE2A 3U7UG 2VJ3A 1KLJL 2W3IB 3LIWB 1FJSL 2VVVL 2VRSA 5CKMA 2BT7A 3FBYA 3SOQA 1FFMA 4NGAL 1QFKL 3S6XA 1JL9A 2WZPP 5JBCE 4D90A 1DX5I 1HRFA 4XL1A 3FFGL 1NZIA 1G1QA 2FLRL 2WFXB 1RFNB 1K36A 1L3YA 1M1XB 4M10A 5JW1A 2JKHL 2XC4L 1G1SA 2WPIE 2VVUL 2BT8A 2P95L 3N8YB 3KQDL 2VVCK 1WHEA 3NTBA 1FF7A 3HS7A 1QIUA 3CA7A 4BXWA 4Y76B 1YUGA 3RR3A 3SOBB 1LPKA 2OYUP 3BT1A 2NPRA 1I0UA 3KK6A 2BOKL 5IKQA 1JV2B 5F1AA 3BPSE 2P26A 4M11A 1AUTL 2Y80B 3TGFA 1W7XL 1B9WA 3CFWA 4RS0A 1NPEB 6COXA 4ZH8B 3SOVA 1CEJA 4RRWA 4FM5A 3V65B 2XBXL 1EQGA 3TH3L 3PGHA 1ATDA 2W26B 1LMJA 3CENL 4Y6DB 5KN5C 2FZZL 2Y38A 1HAEA 2Y81B 2BQWA 3IITB 3P5BL 1G2MB 2YGQA 1HZ8A 3NJPC 1PFXL 2P3FL 4CUDA 4A94C 4Z0LA 1JBUL 4JZFL 1IP0A 4LORA 1EMNA 4ZAEB 1HT8A 3N8YA 4OTYA 2RHPA 1IVOC 4COXA 1CCVA 1IQFL 4XBMA 4CSYA 4RRXA 1KIGL 1G1RA 3LN0A 2W2PE 2VWNL 1LPZA 4AQTA 1IOEL 3OLUA 3DEMA 1IQLL 3LN1A 2J4IB 2VH0B 4BTIA 1UZJA 2K2TA 2WFTA 3HS6A 2VWOL 1DDXA 1IOXA 1PXXA 1SZBA 1PTHA 1V1HA 1TOZA 2BOXA 3HO4A 3F6UL 1ATAA 5IKRA 5JVYA 1J9CL 3LAQA 5KIRA 5FDQA 2K2SB 5F19A 1CVWL 3GCWE 4MMXB 2Y82B 1EQHA 1MQ5L 3LTFB 2BZ6L 1IQHL 1DVAL 3NT1A 4MMYB 2WPME 1L5GB 3LC5B 5COXA 4BXSA 1KLOA 1XKBA 1IQKL 1URKA 1KSNB 3KCGL 1BF9A 1EBVA 1O5DL 4OTJA 4O02B 1ATEA 2Y5GL 1W8BL 4D0EA 5L30L 3M36L 2Q1JB 2EI8B 4G1MB 1LMMA 2P3UA 2J94B 2H9EL 2J2UB 2VWLL 4Y71B 1TPGA 2BOUA 3M37L 2KL7A 4ZHAB 1NFUB 1N1IA 5JBAE 4YT7L 1LK9A 2P94L 1U8CB 1F0RB 1UZPA 4ZXXL 2KNIA 2P3FN 2CJIB 1IQEL 1K37A 2WYJB 1EMOA 2EI6B 4A7IA 1FSBA 1OB1C 1PGEA 3FCSB 2G00L 3HO5A 3QH0A 3EGFA 3KQBL 1XFEA 1ZAQA 1IGZA 2W2QE 4ZXYL 1NFWB 2MHPA 4YZUB 2P16L 3F1SB 1UZQA 4BDWA 1YUKB
chains in the Genus database with same CATH topology
3POYA 3CS7L 1KLIL 1Q4GA 4RRZA 1N7DA 3TZIA 2WPKE 2D1JB 1F7EA 1CQEA 2Y5HL 2W2OE 2EI7B 1WU1B 5JB9E 3QCWA 3HPTA 2YGPA 2P28B 3ZYJB 2RA0L 2WPLE 4Z6AL 4LMFA 1V3XB 4JZEL 2J34B 2AYLA 5JB8E 1F0SB 3LC3B 4CUEA 1X7AL 3SW2A 5JVZA 5CKNA 3N8VA 1IJQA 2XC5L 2OYEP 2XBYL 3HS5A 3ENSA 3N8WB 4TGFA 3KQCL 4Y7AB 2F9BL 2FLGA 2KB9A 1EPHA 1HCGB 2XBVL 4NG9L 4E1GA 4ISIL 1YUFA 2MGRA 2I9BA 4ISHL 1HX2A 1IQGL 1DIYA 1COUA 1IQML 4O1ZA 5L2YL 1Z6CA 2YGOA 2Y7ZB 2Y5FL 3ELAL 2WYGB 3TK6B 2W2NE 3TBDA 1CX2A 2WG3C 2BMGA 4JYVL 1EGFA 2BOHA 2MGPA 4Y7BB 2M74A 2W2ME 2ADXA 5IKVA 3ASIA 3LTGD 1F7MA 2B7DL 2XC0L 1IQJL 1IQIL 2UWPB 2I9AA 4CUFA 5CISA 1HT5A 1MQ6L 1IGXA 1FAXL 1U67A 2WPJE 1YO8A 4BDXA 1TLEA 4YT6L 1NFYB 4BTTA 1EPIA 2P93L 2XBWL 2KV4A 3N8WA 1YGCL 3V64C 1C5MF 3BT2A 3KRKA 1APQA 2PR3B 3HO3A 3KL6B 3GISX 4Y79B 2TGFA 1DQBA 3OLTA 1MOXC 1GK5A 1XDTR 1EPGA 2DDUA 5IKTA 2FLBL 1EZQB 2J95B 4X8VL 1Z6EL 2W86A 1G2LB 2BQ6A 5JBBE 1UZKA 2BO2A 2WG4B 2VWMK 3ZYIB 3NTGA 5I46L 3MQEA 1APOA 3N8ZA 3H5CB 1CCFA 1FAKL 1IQNL 3ZYGA 2VH6B 3N8XA 2UWLB 4BTUA 1EPJA 3IJEB 1LQDA 4JYUL 1NFXB 1G1TA 4X8TL 2UWOB 2FD6A 1P0SL 3U73A 4C16A 2J38B 5EGMB 1NT0A 2PHBB 1PRHA 4RUTA 1CVUA 1P9JA 4JZDL 1ATBA 4X8SL 4NA9L 5K0HB 4MMZB 5L2ZL 3QMOA 1LPGA 1EAIC 3Q7DA 3K9XA 2PUQL 1NQLB 3Q3KB 2BQ7A 4RRYA 3C9AC 3MDLA 5E8DA 3KQEL 2GD4A 4XLWA 1WHFA 4Z0KB 2Y7XB 1HJ7A 4PH9A 1HREA 4D0FA 2WPHE 1ADXA 1XKAL 2W3KB 5CKQA 1HAFA 1A3PA 3TK5B 2RNLA 3R05A 2P3TA 2H9EC 3GCXE 4X8UL 1FE2A 3U7UG 2VJ3A 1KLJL 2W3IB 3LIWB 1FJSL 2VVVL 5CKMA 3FBYA 3SOQA 1FFMA 4NGAL 1QFKL 3S6XA 1JL9A 2WZPP 5JBCE 4D90A 1DX5I 1HRFA 4XL1A 3FFGL 1NZIA 1G1QA 2FLRL 2WFXB 1RFNB 1K36A 1L3YA 1M1XB 4M10A 5JW1A 2JKHL 2XC4L 1G1SA 2WPIE 2VVUL 2P95L 3N8YB 3KQDL 2VVCK 1WHEA 3NTBA 1FF7A 3HS7A 3CA7A 4BXWA 4Y76B 1YUGA 3RR3A 3SOBB 1LPKA 2OYUP 3BT1A 2NPRA 1I0UA 3KK6A 2BOKL 5IKQA 1JV2B 5F1AA 3BPSE 2P26A 4M11A 1AUTL 2Y80B 3TGFA 1W7XL 1B9WA 3CFWA 4RS0A 1NPEB 6COXA 4ZH8B 3SOVA 1CEJA 4RRWA 4FM5A 3V65B 2XBXL 1EQGA 3TH3L 3PGHA 1ATDA 2W26B 1LMJA 3CENL 4Y6DB 5KN5C 2FZZL 2Y38A 1HAEA 2Y81B 2BQWA 3IITB 3P5BL 1G2MB 2YGQA 1HZ8A 3NJPC 1PFXL 2P3FL 4CUDA 4A94C 4Z0LA 1JBUL 4JZFL 1IP0A 4LORA 1EMNA 4ZAEB 1HT8A 3N8YA 4OTYA 2RHPA 1IVOC 4COXA 1CCVA 1IQFL 4XBMA 4CSYA 4RRXA 1KIGL 1G1RA 3LN0A 2W2PE 2VWNL 1LPZA 4AQTA 1IOEL 3OLUA 3DEMA 1IQLL 3LN1A 2J4IB 2VH0B 4BTIA 1UZJA 2K2TA 2WFTA 3HS6A 2VWOL 1DDXA 1IOXA 1PXXA 1SZBA 1PTHA 1TOZA 2BOXA 3HO4A 3F6UL 1ATAA 5IKRA 5JVYA 1J9CL 3LAQA 5KIRA 5FDQA 2K2SB 5F19A 1CVWL 3GCWE 4MMXB 2Y82B 1EQHA 1MQ5L 3LTFB 2BZ6L 1IQHL 1DVAL 3NT1A 4MMYB 2WPME 1L5GB 3LC5B 5COXA 4BXSA 1KLOA 1XKBA 1IQKL 1URKA 1KSNB 3KCGL 1BF9A 1EBVA 1O5DL 4OTJA 4O02B 1ATEA 2Y5GL 1W8BL 4D0EA 5L30L 3M36L 2Q1JB 2EI8B 4G1MB 1LMMA 2P3UA 2J94B 2H9EL 2J2UB 2VWLL 4Y71B 1TPGA 2BOUA 3M37L 2KL7A 4ZHAB 1NFUB 1N1IA 5JBAE 4YT7L 2P94L 1U8CB 1F0RB 1UZPA 4ZXXL 2KNIA 2P3FN 2CJIB 1IQEL 1K37A 2WYJB 1EMOA 2EI6B 4A7IA 1FSBA 1OB1C 1PGEA 3FCSB 2G00L 3HO5A 3QH0A 3EGFA 3KQBL 1XFEA 1ZAQA 1IGZA 2W2QE 4ZXYL 1NFWB 2MHPA 4YZUB 2P16L 3F1SB 1UZQA 4BDWA 1YUKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3POY A;  3CS7 L;  1KLI L;  1Q4G A;  4RRZ A;  1N7D A;  3TZI A;  2WPK E;  2D1J B;  1F7E A;  1CQE A;  2Y5H L;  2W2O E;  2EI7 B;  1WU1 B;  5JB9 E;  3QCW A;  3HPT A;  2YGP A;  2P28 B;  3ZYJ B;  2RA0 L;  2WPL E;  4Z6A L;  4LMF A;  1V3X B;  4JZE L;  2J34 B;  2AYL A;  5JB8 E;  1F0S B;  3LC3 B;  4CUE A;  1X7A L;  3SW2 A;  5JVZ A;  5CKN A;  3N8V A;  1IJQ A;  2XC5 L;  2OYE P;  2XBY L;  3HS5 A;  3ENS A;  3N8W B;  4TGF A;  3KQC L;  4Y7A B;  2F9B L;  2FLG A;  2KB9 A;  1EPH A;  1HCG B;  2XBV L;  4NG9 L;  4E1G A;  4ISI L;  1YUF A;  2MGR A;  2I9B A;  4ISH L;  1HX2 A;  1IQG L;  1DIY A;  1COU A;  1IQM L;  4O1Z A;  5L2Y L;  1Z6C A;  2YGO A;  2Y7Z B;  2Y5F L;  3ELA L;  2WYG B;  3TK6 B;  2W2N E;  3TBD A;  1CX2 A;  2WG3 C;  2BMG A;  4JYV L;  1EGF A;  2BOH A;  2MGP A;  4Y7B B;  2M74 A;  2W2M E;  2ADX A;  5IKV A;  3ASI A;  3LTG D;  1F7M A;  2B7D L;  2XC0 L;  1IQJ L;  1IQI L;  2UWP B;  2I9A A;  4CUF A;  5CIS A;  1HT5 A;  1MQ6 L;  1IGX A;  1FAX L;  1U67 A;  2WPJ E;  1YO8 A;  4BDX A;  1TLE A;  4YT6 L;  1NFY B;  4BTT A;  1EPI A;  2P93 L;  2XBW L;  2KV4 A;  3N8W A;  1YGC L;  3V64 C;  1C5M F;  3BT2 A;  3KRK A;  1APQ A;  2PR3 B;  3HO3 A;  3KL6 B;  3GIS X;  4Y79 B;  2TGF A;  1DQB A;  3OLT A;  1MOX C;  1GK5 A;  1XDT R;  1EPG A;  2DDU A;  5IKT A;  2FLB L;  1EZQ B;  2J95 B;  4X8V L;  1Z6E L;  2W86 A;  1G2L B;  2BQ6 A;  5JBB E;  1UZK A;  2BO2 A;  2WG4 B;  2VWM K;  3ZYI B;  3NTG A;  5I46 L;  3MQE A;  1APO A;  3N8Z A;  3H5C B;  1CCF A;  1FAK L;  1IQN L;  3ZYG A;  2VH6 B;  3N8X A;  2UWL B;  4BTU A;  1EPJ A;  3IJE B;  1LQD A;  4JYU L;  1NFX B;  1G1T A;  4X8T L;  2UWO B;  2FD6 A;  1P0S L;  3U73 A;  4C16 A;  2J38 B;  5EGM B;  1NT0 A;  2PHB B;  1PRH A;  4RUT A;  1CVU A;  1P9J A;  4JZD L;  1ATB A;  4X8S L;  4NA9 L;  5K0H B;  4MMZ B;  5L2Z L;  3QMO A;  1LPG A;  1EAI C;  3Q7D A;  3K9X A;  2PUQ L;  1NQL B;  3Q3K B;  2BQ7 A;  4RRY A;  3C9A C;  3MDL A;  5E8D A;  3KQE L;  2GD4 A;  4XLW A;  1WHF A;  4Z0K B;  2Y7X B;  1HJ7 A;  4PH9 A;  1HRE A;  4D0F A;  2WPH E;  1ADX A;  1XKA L;  2W3K B;  5CKQ A;  1HAF A;  1A3P A;  3TK5 B;  2RNL A;  3R05 A;  2P3T A;  3GCX E;  4X8U L;  1FE2 A;  3U7U G;  2VJ3 A;  1KLJ L;  2W3I B;  3LIW B;  1FJS L;  2VVV L;  5CKM A;  3FBY A;  3SOQ A;  1FFM A;  4NGA L;  1QFK L;  1JL9 A;  5JBC E;  4D90 A;  1DX5 I;  1HRF A;  4XL1 A;  3FFG L;  1NZI A;  1G1Q A;  2FLR L;  2WFX B;  1RFN B;  1K36 A;  1L3Y A;  1M1X B;  4M10 A;  5JW1 A;  2JKH L;  2XC4 L;  1G1S A;  2WPI E;  2VVU L;  2P95 L;  3N8Y B;  3KQD L;  2VVC K;  1WHE A;  3NTB A;  1FF7 A;  3HS7 A;  3CA7 A;  4BXW A;  4Y76 B;  1YUG A;  3RR3 A;  3SOB B;  1LPK A;  2OYU P;  3BT1 A;  2NPR A;  1I0U A;  3KK6 A;  2BOK L;  5IKQ A;  1JV2 B;  5F1A A;  3BPS E;  2P26 A;  4M11 A;  1AUT L;  2Y80 B;  3TGF A;  1W7X L;  1B9W A;  3CFW A;  4RS0 A;  1NPE B;  6COX A;  4ZH8 B;  3SOV A;  1CEJ A;  4RRW A;  4FM5 A;  3V65 B;  2XBX L;  1EQG A;  3TH3 L;  3PGH A;  1ATD A;  2W26 B;  1LMJ A;  3CEN L;  4Y6D B;  5KN5 C;  2FZZ L;  2Y38 A;  1HAE A;  2Y81 B;  2BQW A;  3IIT B;  3P5B L;  1G2M B;  1HZ8 A;  3NJP C;  1PFX L;  2P3F L;  4CUD A;  4Z0L A;  1JBU L;  4JZF L;  1IP0 A;  4LOR A;  1EMN A;  4ZAE B;  1HT8 A;  3N8Y A;  4OTY A;  2RHP A;  1IVO C;  4COX A;  1CCV A;  1IQF L;  4XBM A;  4CSY A;  4RRX A;  1KIG L;  1G1R A;  3LN0 A;  2W2P E;  2VWN L;  1LPZ A;  4AQT A;  1IOE L;  3OLU A;  3DEM A;  1IQL L;  3LN1 A;  2J4I B;  2VH0 B;  4BTI A;  1UZJ A;  2K2T A;  2WFT A;  3HS6 A;  2VWO L;  1DDX A;  1IOX A;  1PXX A;  1SZB A;  1PTH A;  1TOZ A;  2BOX A;  3HO4 A;  3F6U L;  1ATA A;  5IKR A;  5JVY A;  1J9C L;  3LAQ A;  5KIR A;  5FDQ A;  2K2S B;  5F19 A;  1CVW L;  3GCW E;  4MMX B;  2Y82 B;  1EQH A;  1MQ5 L;  3LTF B;  2BZ6 L;  1IQH L;  1DVA L;  3NT1 A;  4MMY B;  2WPM E;  1L5G B;  3LC5 B;  5COX A;  4BXS A;  1KLO A;  1XKB A;  1IQK L;  1URK A;  1KSN B;  3KCG L;  1BF9 A;  1EBV A;  1O5D L;  4OTJ A;  4O02 B;  1ATE A;  2Y5G L;  1W8B L;  4D0E A;  5L30 L;  3M36 L;  2Q1J B;  2EI8 B;  4G1M B;  2P3U A;  2J94 B;  2H9E L;  2J2U B;  2VWL L;  4Y71 B;  1TPG A;  2BOU A;  3M37 L;  2KL7 A;  4ZHA B;  1NFU B;  1N1I A;  5JBA E;  4YT7 L;  2P94 L;  1U8C B;  1F0R B;  1UZP A;  4ZXX L;  2P3F N;  2CJI B;  1IQE L;  1K37 A;  2WYJ B;  1EMO A;  2EI6 B;  4A7I A;  1FSB A;  1OB1 C;  1PGE A;  3FCS B;  2G00 L;  3HO5 A;  3QH0 A;  3EGF A;  3KQB L;  1XFE A;  1ZAQ A;  1IGZ A;  2W2Q E;  4ZXY L;  1NFW B;  2MHP A;  4YZU B;  2P16 L;  3F1S B;  1UZQ A;  4BDW A;  1YUK B; 
#chains in the Genus database with same CATH topology
 3POY A;  1V1I A;  3CS7 L;  1KLI L;  1Q4G A;  4RRZ A;  1N7D A;  3TZI A;  2WPK E;  2D1J B;  1F7E A;  4GU4 A;  1CQE A;  2Y5H L;  2W2O E;  2EI7 B;  1WU1 B;  5JB9 E;  3QCW A;  3HPT A;  2YGP A;  2P28 B;  3ZYJ B;  2RA0 L;  2WPL E;  4Z6A L;  4LMF A;  1V3X B;  4JZE L;  2J34 B;  2AYL A;  5JB8 E;  1F0S B;  3LC3 B;  4CUE A;  1X7A L;  3SW2 A;  5JVZ A;  5CKN A;  3N8V A;  1IJQ A;  2XC5 L;  2OYE P;  2XBY L;  3HS5 A;  3ENS A;  3N8W B;  4TGF A;  3KQC L;  4Y7A B;  4GU3 A;  2F9B L;  2FLG A;  2KB9 A;  1EPH A;  1HCG B;  2XBV L;  4NG9 L;  4E1G A;  4ISI L;  1YUF A;  2MGR A;  2I9B A;  4ISH L;  1HX2 A;  1IQG L;  1DIY A;  1COU A;  1IQM L;  4O1Z A;  5L2Y L;  1Z6C A;  2YGO A;  2Y7Z B;  2Y5F L;  3ELA L;  2WYG B;  3TK6 B;  2W2N E;  3TBD A;  1CX2 A;  2WG3 C;  2HOX A;  2BMG A;  4JYV L;  1EGF A;  2BOH A;  2MGP A;  4Y7B B;  2M74 A;  2W2M E;  2ADX A;  5IKV A;  3ASI A;  3LTG D;  1F7M A;  2HOR A;  2B7D L;  2XC0 L;  1IQJ L;  1IQI L;  2UWP B;  2I9A A;  4CUF A;  5CIS A;  1KKE A;  1HT5 A;  1MQ6 L;  1IGX A;  1FAX L;  1U67 A;  2WPJ E;  1YO8 A;  4BDX A;  1TLE A;  4YT6 L;  1NFY B;  4BTT A;  1EPI A;  2P93 L;  2XBW L;  2KV4 A;  3N8W A;  1YGC L;  3V64 C;  1C5M F;  3BT2 A;  2BSF A;  3KRK A;  1APQ A;  2PR3 B;  3HO3 A;  3KL6 B;  3GIS X;  4Y79 B;  2TGF A;  1DQB A;  3OLT A;  1MOX C;  1GK5 A;  1XDT R;  1EPG A;  2DDU A;  5IKT A;  2FLB L;  2JJL A;  1EZQ B;  2J95 B;  4X8V L;  1Z6E L;  2W86 A;  1G2L B;  2BQ6 A;  5JBB E;  1UZK A;  2BO2 A;  2WG4 B;  2VWM K;  3ZYI B;  3NTG A;  5I46 L;  3MQE A;  1APO A;  3N8Z A;  3H5C B;  1CCF A;  1FAK L;  1IQN L;  3ZYG A;  2VH6 B;  3N8X A;  2UWL B;  4BTU A;  1EPJ A;  3IJE B;  1LQD A;  4JYU L;  1NFX B;  1G1T A;  4X8T L;  2UWO B;  2FD6 A;  1P0S L;  3U73 A;  4C16 A;  2J38 B;  5EGM B;  1NT0 A;  2PHB B;  1PRH A;  4RUT A;  1CVU A;  1P9J A;  4JZD L;  1ATB A;  4X8S L;  4NA9 L;  5K0H B;  4MMZ B;  5L2Z L;  3QMO A;  1LPG A;  1EAI C;  3Q7D A;  3K9X A;  2PUQ L;  1NQL B;  3Q3K B;  2BQ7 A;  4RRY A;  3C9A C;  3MDL A;  5E8D A;  3KQE L;  2GD4 A;  4XLW A;  1WHF A;  4Z0K B;  2Y7X B;  1HJ7 A;  4PH9 A;  1HRE A;  4D0F A;  2WPH E;  1ADX A;  1XKA L;  2W3K B;  5CKQ A;  1HAF A;  1A3P A;  3TK5 B;  2RNL A;  3R05 A;  2P3T A;  2H9E C;  3GCX E;  4X8U L;  1FE2 A;  3U7U G;  2VJ3 A;  1KLJ L;  2W3I B;  3LIW B;  1FJS L;  2VVV L;  2VRS A;  5CKM A;  2BT7 A;  3FBY A;  3SOQ A;  1FFM A;  4NGA L;  1QFK L;  3S6X A;  1JL9 A;  2WZP P;  5JBC E;  4D90 A;  1DX5 I;  1HRF A;  4XL1 A;  3FFG L;  1NZI A;  1G1Q A;  2FLR L;  2WFX B;  1RFN B;  1K36 A;  1L3Y A;  1M1X B;  4M10 A;  5JW1 A;  2JKH L;  2XC4 L;  1G1S A;  2WPI E;  2VVU L;  2BT8 A;  2P95 L;  3N8Y B;  3KQD L;  2VVC K;  1WHE A;  3NTB A;  1FF7 A;  3HS7 A;  1QIU A;  3CA7 A;  4BXW A;  4Y76 B;  1YUG A;  3RR3 A;  3SOB B;  1LPK A;  2OYU P;  3BT1 A;  2NPR A;  1I0U A;  3KK6 A;  2BOK L;  5IKQ A;  1JV2 B;  5F1A A;  3BPS E;  2P26 A;  4M11 A;  1AUT L;  2Y80 B;  3TGF A;  1W7X L;  1B9W A;  3CFW A;  4RS0 A;  1NPE B;  6COX A;  4ZH8 B;  3SOV A;  1CEJ A;  4RRW A;  4FM5 A;  3V65 B;  2XBX L;  1EQG A;  3TH3 L;  3PGH A;  1ATD A;  2W26 B;  1LMJ A;  3CEN L;  4Y6D B;  5KN5 C;  2FZZ L;  2Y38 A;  1HAE A;  2Y81 B;  2BQW A;  3IIT B;  3P5B L;  1G2M B;  2YGQ A;  1HZ8 A;  3NJP C;  1PFX L;  2P3F L;  4CUD A;  4A94 C;  4Z0L A;  1JBU L;  4JZF L;  1IP0 A;  4LOR A;  1EMN A;  4ZAE B;  1HT8 A;  3N8Y A;  4OTY A;  2RHP A;  1IVO C;  4COX A;  1CCV A;  1IQF L;  4XBM A;  4CSY A;  4RRX A;  1KIG L;  1G1R A;  3LN0 A;  2W2P E;  2VWN L;  1LPZ A;  4AQT A;  1IOE L;  3OLU A;  3DEM A;  1IQL L;  3LN1 A;  2J4I B;  2VH0 B;  4BTI A;  1UZJ A;  2K2T A;  2WFT A;  3HS6 A;  2VWO L;  1DDX A;  1IOX A;  1PXX A;  1SZB A;  1PTH A;  1V1H A;  1TOZ A;  2BOX A;  3HO4 A;  3F6U L;  1ATA A;  5IKR A;  5JVY A;  1J9C L;  3LAQ A;  5KIR A;  5FDQ A;  2K2S B;  5F19 A;  1CVW L;  3GCW E;  4MMX B;  2Y82 B;  1EQH A;  1MQ5 L;  3LTF B;  2BZ6 L;  1IQH L;  1DVA L;  3NT1 A;  4MMY B;  2WPM E;  1L5G B;  3LC5 B;  5COX A;  4BXS A;  1KLO A;  1XKB A;  1IQK L;  1URK A;  1KSN B;  3KCG L;  1BF9 A;  1EBV A;  1O5D L;  4OTJ A;  4O02 B;  1ATE A;  2Y5G L;  1W8B L;  4D0E A;  5L30 L;  3M36 L;  2Q1J B;  2EI8 B;  4G1M B;  1LMM A;  2P3U A;  2J94 B;  2H9E L;  2J2U B;  2VWL L;  4Y71 B;  1TPG A;  2BOU A;  3M37 L;  2KL7 A;  4ZHA B;  1NFU B;  1N1I A;  5JBA E;  4YT7 L;  1LK9 A;  2P94 L;  1U8C B;  1F0R B;  1UZP A;  4ZXX L;  2KNI A;  2P3F N;  2CJI B;  1IQE L;  1K37 A;  2WYJ B;  1EMO A;  2EI6 B;  4A7I A;  1FSB A;  1OB1 C;  1PGE A;  3FCS B;  2G00 L;  3HO5 A;  3QH0 A;  3EGF A;  3KQB L;  1XFE A;  1ZAQ A;  1IGZ A;  2W2Q E;  4ZXY L;  1NFW B;  2MHP A;  4YZU B;  2P16 L;  3F1S B;  1UZQ A;  4BDW A;  1YUK B; 
#chains in the Genus database with same CATH homology
 3POY A;  3CS7 L;  1KLI L;  1Q4G A;  4RRZ A;  1N7D A;  3TZI A;  2WPK E;  2D1J B;  1F7E A;  1CQE A;  2Y5H L;  2W2O E;  2EI7 B;  1WU1 B;  5JB9 E;  3QCW A;  3HPT A;  2YGP A;  2P28 B;  3ZYJ B;  2RA0 L;  2WPL E;  4Z6A L;  4LMF A;  1V3X B;  4JZE L;  2J34 B;  2AYL A;  5JB8 E;  1F0S B;  3LC3 B;  4CUE A;  1X7A L;  3SW2 A;  5JVZ A;  5CKN A;  3N8V A;  1IJQ A;  2XC5 L;  2OYE P;  2XBY L;  3HS5 A;  3ENS A;  3N8W B;  4TGF A;  3KQC L;  4Y7A B;  2F9B L;  2FLG A;  2KB9 A;  1EPH A;  1HCG B;  2XBV L;  4NG9 L;  4E1G A;  4ISI L;  1YUF A;  2MGR A;  2I9B A;  4ISH L;  1HX2 A;  1IQG L;  1DIY A;  1COU A;  1IQM L;  4O1Z A;  5L2Y L;  1Z6C A;  2YGO A;  2Y7Z B;  2Y5F L;  3ELA L;  2WYG B;  3TK6 B;  2W2N E;  3TBD A;  1CX2 A;  2WG3 C;  2BMG A;  4JYV L;  1EGF A;  2BOH A;  2MGP A;  4Y7B B;  2M74 A;  2W2M E;  2ADX A;  5IKV A;  3ASI A;  3LTG D;  1F7M A;  2B7D L;  2XC0 L;  1IQJ L;  1IQI L;  2UWP B;  2I9A A;  4CUF A;  5CIS A;  1HT5 A;  1MQ6 L;  1IGX A;  1FAX L;  1U67 A;  2WPJ E;  1YO8 A;  4BDX A;  1TLE A;  4YT6 L;  1NFY B;  4BTT A;  1EPI A;  2P93 L;  2XBW L;  2KV4 A;  3N8W A;  1YGC L;  3V64 C;  1C5M F;  3BT2 A;  3KRK A;  1APQ A;  2PR3 B;  3HO3 A;  3KL6 B;  3GIS X;  4Y79 B;  2TGF A;  1DQB A;  3OLT A;  1MOX C;  1GK5 A;  1XDT R;  1EPG A;  2DDU A;  5IKT A;  2FLB L;  1EZQ B;  2J95 B;  4X8V L;  1Z6E L;  2W86 A;  1G2L B;  2BQ6 A;  5JBB E;  1UZK A;  2BO2 A;  2WG4 B;  2VWM K;  3ZYI B;  3NTG A;  5I46 L;  3MQE A;  1APO A;  3N8Z A;  3H5C B;  1CCF A;  1FAK L;  1IQN L;  3ZYG A;  2VH6 B;  3N8X A;  2UWL B;  4BTU A;  1EPJ A;  3IJE B;  1LQD A;  4JYU L;  1NFX B;  1G1T A;  4X8T L;  2UWO B;  2FD6 A;  1P0S L;  3U73 A;  4C16 A;  2J38 B;  5EGM B;  1NT0 A;  2PHB B;  1PRH A;  4RUT A;  1CVU A;  1P9J A;  4JZD L;  1ATB A;  4X8S L;  4NA9 L;  5K0H B;  4MMZ B;  5L2Z L;  3QMO A;  1LPG A;  1EAI C;  3Q7D A;  3K9X A;  2PUQ L;  1NQL B;  3Q3K B;  2BQ7 A;  4RRY A;  3C9A C;  3MDL A;  5E8D A;  3KQE L;  2GD4 A;  4XLW A;  1WHF A;  4Z0K B;  2Y7X B;  1HJ7 A;  4PH9 A;  1HRE A;  4D0F A;  2WPH E;  1ADX A;  1XKA L;  2W3K B;  5CKQ A;  1HAF A;  1A3P A;  3TK5 B;  2RNL A;  3R05 A;  2P3T A;  2H9E C;  3GCX E;  4X8U L;  1FE2 A;  3U7U G;  2VJ3 A;  1KLJ L;  2W3I B;  3LIW B;  1FJS L;  2VVV L;  5CKM A;  3FBY A;  3SOQ A;  1FFM A;  4NGA L;  1QFK L;  3S6X A;  1JL9 A;  2WZP P;  5JBC E;  4D90 A;  1DX5 I;  1HRF A;  4XL1 A;  3FFG L;  1NZI A;  1G1Q A;  2FLR L;  2WFX B;  1RFN B;  1K36 A;  1L3Y A;  1M1X B;  4M10 A;  5JW1 A;  2JKH L;  2XC4 L;  1G1S A;  2WPI E;  2VVU L;  2P95 L;  3N8Y B;  3KQD L;  2VVC K;  1WHE A;  3NTB A;  1FF7 A;  3HS7 A;  3CA7 A;  4BXW A;  4Y76 B;  1YUG A;  3RR3 A;  3SOB B;  1LPK A;  2OYU P;  3BT1 A;  2NPR A;  1I0U A;  3KK6 A;  2BOK L;  5IKQ A;  1JV2 B;  5F1A A;  3BPS E;  2P26 A;  4M11 A;  1AUT L;  2Y80 B;  3TGF A;  1W7X L;  1B9W A;  3CFW A;  4RS0 A;  1NPE B;  6COX A;  4ZH8 B;  3SOV A;  1CEJ A;  4RRW A;  4FM5 A;  3V65 B;  2XBX L;  1EQG A;  3TH3 L;  3PGH A;  1ATD A;  2W26 B;  1LMJ A;  3CEN L;  4Y6D B;  5KN5 C;  2FZZ L;  2Y38 A;  1HAE A;  2Y81 B;  2BQW A;  3IIT B;  3P5B L;  1G2M B;  2YGQ A;  1HZ8 A;  3NJP C;  1PFX L;  2P3F L;  4CUD A;  4A94 C;  4Z0L A;  1JBU L;  4JZF L;  1IP0 A;  4LOR A;  1EMN A;  4ZAE B;  1HT8 A;  3N8Y A;  4OTY A;  2RHP A;  1IVO C;  4COX A;  1CCV A;  1IQF L;  4XBM A;  4CSY A;  4RRX A;  1KIG L;  1G1R A;  3LN0 A;  2W2P E;  2VWN L;  1LPZ A;  4AQT A;  1IOE L;  3OLU A;  3DEM A;  1IQL L;  3LN1 A;  2J4I B;  2VH0 B;  4BTI A;  1UZJ A;  2K2T A;  2WFT A;  3HS6 A;  2VWO L;  1DDX A;  1IOX A;  1PXX A;  1SZB A;  1PTH A;  1TOZ A;  2BOX A;  3HO4 A;  3F6U L;  1ATA A;  5IKR A;  5JVY A;  1J9C L;  3LAQ A;  5KIR A;  5FDQ A;  2K2S B;  5F19 A;  1CVW L;  3GCW E;  4MMX B;  2Y82 B;  1EQH A;  1MQ5 L;  3LTF B;  2BZ6 L;  1IQH L;  1DVA L;  3NT1 A;  4MMY B;  2WPM E;  1L5G B;  3LC5 B;  5COX A;  4BXS A;  1KLO A;  1XKB A;  1IQK L;  1URK A;  1KSN B;  3KCG L;  1BF9 A;  1EBV A;  1O5D L;  4OTJ A;  4O02 B;  1ATE A;  2Y5G L;  1W8B L;  4D0E A;  5L30 L;  3M36 L;  2Q1J B;  2EI8 B;  4G1M B;  1LMM A;  2P3U A;  2J94 B;  2H9E L;  2J2U B;  2VWL L;  4Y71 B;  1TPG A;  2BOU A;  3M37 L;  2KL7 A;  4ZHA B;  1NFU B;  1N1I A;  5JBA E;  4YT7 L;  2P94 L;  1U8C B;  1F0R B;  1UZP A;  4ZXX L;  2KNI A;  2P3F N;  2CJI B;  1IQE L;  1K37 A;  2WYJ B;  1EMO A;  2EI6 B;  4A7I A;  1FSB A;  1OB1 C;  1PGE A;  3FCS B;  2G00 L;  3HO5 A;  3QH0 A;  3EGF A;  3KQB L;  1XFE A;  1ZAQ A;  1IGZ A;  2W2Q E;  4ZXY L;  1NFW B;  2MHP A;  4YZU B;  2P16 L;  3F1S B;  1UZQ A;  4BDW A;  1YUK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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