2K7XA

Solution structure of c-terminal domain of sars-cov main protease
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
120
structure length
120
Chain Sequence
DRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer.
pubmed doi rcsb
molecule tags Hydrolase
source organism Sars coronavirus
molecule keywords SARS-CoV main protease
total genus 37
structure length 120
sequence length 120
ec nomenclature
pdb deposition date 2008-08-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1840.10 Mainly Alpha Orthogonal Bundle main proteinase (3clpro) structure, domain 3 main proteinase (3clpro) structure, domain 3 2k7xA00
3F9GA 3F9EA 5EU8A 2ZU4A 2QC2A 3EA9A 2PWXA 5C5NA 3VB4A 4WMDA 2GT8A 2H2ZA 3V3MA 2AMPA 3SNCA 3SZNA 3AW0A 4HI3A 2AMDA 1P9SA 2DUCA 2Z9GA 2GX4A 3ATWA 1LVOA 2Z9LA 2GZ7A 3SNBA 2ZU5A 4YOJA 4XFQA 2Z3CA 2Z94A 2BX4A 1Z1JA 5C3NA 4YLUA 3SN8A 3AW1A 3M3SA 4TWYA 3F9FA 2Q6FA 2BX3A 4RSPA 1UK4A 2YNAA 3FZDA 3TIUA 3SNDA 3TLOA 2QCYA 2A5IA 2GTBA 3EA7A 5C5OA 4WY3A 3EAJA 1Q2WA 4YOGA 4F49A 3TNTA 4WMFA 2A5AA 1UK3A 2K7XA 2ALVA 3VB6A 2Q6GA 1WOFA 2VJ1A 1UK2A 3VB5A 3SNEA 2ZU2A 2HOBA 3D62A 2GT7A 2OP9A 5GWZA 2V6NA 3TNSA 2Z9KA 2Z3EA 5B6OA 3M3VA 2LIZA 4ZUHA 2D2DA 3SNAA 4WMEA 3VB7A 2A5KA 3D23A 4YO9A 3IWMA 1UJ1A 3TITA 3VB3A 2AMQA 2GZ8A 3AVZA 3F9HA 2QIQA 3EBNA 2Q6DA 2Z9JA 4MDSA 5HYOA 3E91A 2Z3DA 3M3TA 4TWWA 2GZ9A 4YOIA 1Z1IA 4ZROA 1P9UA 2C3SA 3EA8A 2YNBA
chains in the Genus database with same CATH superfamily
3F9GA 3F9EA 5EU8A 2ZU4A 2QC2A 3EA9A 2PWXA 5C5NA 3VB4A 4WMDA 2GT8A 2H2ZA 3V3MA 2AMPA 3SNCA 3SZNA 3AW0A 4HI3A 2AMDA 1P9SA 2DUCA 2Z9GA 2GX4A 3ATWA 1LVOA 2Z9LA 2GZ7A 3SNBA 2ZU5A 4YOJA 4XFQA 2Z3CA 2Z94A 2BX4A 1Z1JA 5C3NA 4YLUA 3SN8A 3AW1A 3M3SA 4TWYA 3F9FA 2Q6FA 2BX3A 4RSPA 1UK4A 2YNAA 3FZDA 3TIUA 3SNDA 3TLOA 2QCYA 2A5IA 2GTBA 3EA7A 5C5OA 4WY3A 3EAJA 1Q2WA 4YOGA 4F49A 3TNTA 4WMFA 2A5AA 1UK3A 2K7XA 2ALVA 3VB6A 2Q6GA 1WOFA 2VJ1A 1UK2A 3VB5A 3SNEA 2ZU2A 2HOBA 3D62A 2GT7A 2OP9A 5GWZA 2V6NA 3TNSA 2Z9KA 2Z3EA 5B6OA 3M3VA 2LIZA 4ZUHA 2D2DA 3SNAA 4WMEA 3VB7A 2A5KA 3D23A 4YO9A 3IWMA 1UJ1A 3TITA 3VB3A 2AMQA 2GZ8A 3AVZA 3F9HA 2QIQA 3EBNA 2Q6DA 2Z9JA 4MDSA 5HYOA 3E91A 2Z3DA 3M3TA 4TWWA 2GZ9A 4YOIA 1Z1IA 4ZROA 1P9UA 2C3SA 3EA8A 2YNBA
chains in the Genus database with same CATH topology
3F9GA 3F9EA 5EU8A 2ZU4A 2QC2A 3EA9A 2PWXA 5C5NA 3VB4A 4WMDA 2GT8A 2H2ZA 3V3MA 2AMPA 3SNCA 3SZNA 3AW0A 4HI3A 2AMDA 1P9SA 2DUCA 2Z9GA 2GX4A 3ATWA 1LVOA 2Z9LA 2GZ7A 3SNBA 2ZU5A 4YOJA 4XFQA 2Z3CA 2Z94A 2BX4A 1Z1JA 5C3NA 4YLUA 3SN8A 3AW1A 3M3SA 4TWYA 3F9FA 2Q6FA 2BX3A 4RSPA 1UK4A 2YNAA 3FZDA 3TIUA 3SNDA 3TLOA 2QCYA 2A5IA 2GTBA 3EA7A 5C5OA 4WY3A 3EAJA 1Q2WA 4YOGA 4F49A 3TNTA 4WMFA 2A5AA 1UK3A 2K7XA 2ALVA 3VB6A 2Q6GA 1WOFA 2VJ1A 1UK2A 3VB5A 3SNEA 2ZU2A 2HOBA 3D62A 2GT7A 2OP9A 5GWZA 2V6NA 3TNSA 2Z9KA 2Z3EA 5B6OA 3M3VA 2LIZA 4ZUHA 2D2DA 3SNAA 4WMEA 3VB7A 2A5KA 3D23A 4YO9A 3IWMA 1UJ1A 3TITA 3VB3A 2AMQA 2GZ8A 3AVZA 3F9HA 2QIQA 3EBNA 2Q6DA 2Z9JA 4MDSA 5HYOA 3E91A 2Z3DA 3M3TA 4TWWA 2GZ9A 4YOIA 1Z1IA 4ZROA 1P9UA 2C3SA 3EA8A 2YNBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F9G A;  3F9E A;  5EU8 A;  2ZU4 A;  2QC2 A;  3EA9 A;  2PWX A;  5C5N A;  3VB4 A;  4WMD A;  2GT8 A;  2H2Z A;  3V3M A;  2AMP A;  3SNC A;  3SZN A;  3AW0 A;  4HI3 A;  2AMD A;  1P9S A;  2DUC A;  2Z9G A;  2GX4 A;  3ATW A;  1LVO A;  2Z9L A;  2GZ7 A;  3SNB A;  2ZU5 A;  4YOJ A;  4XFQ A;  2Z3C A;  2Z94 A;  2BX4 A;  1Z1J A;  5C3N A;  4YLU A;  3SN8 A;  3AW1 A;  3M3S A;  4TWY A;  3F9F A;  2Q6F A;  2BX3 A;  4RSP A;  1UK4 A;  2YNA A;  3FZD A;  3TIU A;  3SND A;  3TLO A;  2QCY A;  2A5I A;  2GTB A;  3EA7 A;  5C5O A;  4WY3 A;  3EAJ A;  1Q2W A;  4YOG A;  4F49 A;  3TNT A;  4WMF A;  2A5A A;  1UK3 A;  2K7X A;  2ALV A;  3VB6 A;  2Q6G A;  1WOF A;  2VJ1 A;  1UK2 A;  3VB5 A;  3SNE A;  2ZU2 A;  2HOB A;  3D62 A;  2GT7 A;  2OP9 A;  5GWZ A;  2V6N A;  3TNS A;  2Z9K A;  2Z3E A;  5B6O A;  3M3V A;  2LIZ A;  4ZUH A;  2D2D A;  3SNA A;  4WME A;  3VB7 A;  2A5K A;  3D23 A;  4YO9 A;  3IWM A;  1UJ1 A;  3TIT A;  3VB3 A;  2AMQ A;  2GZ8 A;  3AVZ A;  3F9H A;  2QIQ A;  3EBN A;  2Q6D A;  2Z9J A;  4MDS A;  5HYO A;  3E91 A;  2Z3D A;  3M3T A;  4TWW A;  2GZ9 A;  4YOI A;  1Z1I A;  4ZRO A;  1P9U A;  2C3S A;  3EA8 A;  2YNB A; 
#chains in the Genus database with same CATH topology
 3F9G A;  3F9E A;  5EU8 A;  2ZU4 A;  2QC2 A;  3EA9 A;  2PWX A;  5C5N A;  3VB4 A;  4WMD A;  2GT8 A;  2H2Z A;  3V3M A;  2AMP A;  3SNC A;  3SZN A;  3AW0 A;  4HI3 A;  2AMD A;  1P9S A;  2DUC A;  2Z9G A;  2GX4 A;  3ATW A;  1LVO A;  2Z9L A;  2GZ7 A;  3SNB A;  2ZU5 A;  4YOJ A;  4XFQ A;  2Z3C A;  2Z94 A;  2BX4 A;  1Z1J A;  5C3N A;  4YLU A;  3SN8 A;  3AW1 A;  3M3S A;  4TWY A;  3F9F A;  2Q6F A;  2BX3 A;  4RSP A;  1UK4 A;  2YNA A;  3FZD A;  3TIU A;  3SND A;  3TLO A;  2QCY A;  2A5I A;  2GTB A;  3EA7 A;  5C5O A;  4WY3 A;  3EAJ A;  1Q2W A;  4YOG A;  4F49 A;  3TNT A;  4WMF A;  2A5A A;  1UK3 A;  2K7X A;  2ALV A;  3VB6 A;  2Q6G A;  1WOF A;  2VJ1 A;  1UK2 A;  3VB5 A;  3SNE A;  2ZU2 A;  2HOB A;  3D62 A;  2GT7 A;  2OP9 A;  5GWZ A;  2V6N A;  3TNS A;  2Z9K A;  2Z3E A;  5B6O A;  3M3V A;  2LIZ A;  4ZUH A;  2D2D A;  3SNA A;  4WME A;  3VB7 A;  2A5K A;  3D23 A;  4YO9 A;  3IWM A;  1UJ1 A;  3TIT A;  3VB3 A;  2AMQ A;  2GZ8 A;  3AVZ A;  3F9H A;  2QIQ A;  3EBN A;  2Q6D A;  2Z9J A;  4MDS A;  5HYO A;  3E91 A;  2Z3D A;  3M3T A;  4TWW A;  2GZ9 A;  4YOI A;  1Z1I A;  4ZRO A;  1P9U A;  2C3S A;  3EA8 A;  2YNB A; 
#chains in the Genus database with same CATH homology
 3F9G A;  3F9E A;  5EU8 A;  2ZU4 A;  2QC2 A;  3EA9 A;  2PWX A;  5C5N A;  3VB4 A;  4WMD A;  2GT8 A;  2H2Z A;  3V3M A;  2AMP A;  3SNC A;  3SZN A;  3AW0 A;  4HI3 A;  2AMD A;  1P9S A;  2DUC A;  2Z9G A;  2GX4 A;  3ATW A;  1LVO A;  2Z9L A;  2GZ7 A;  3SNB A;  2ZU5 A;  4YOJ A;  4XFQ A;  2Z3C A;  2Z94 A;  2BX4 A;  1Z1J A;  5C3N A;  4YLU A;  3SN8 A;  3AW1 A;  3M3S A;  4TWY A;  3F9F A;  2Q6F A;  2BX3 A;  4RSP A;  1UK4 A;  2YNA A;  3FZD A;  3TIU A;  3SND A;  3TLO A;  2QCY A;  2A5I A;  2GTB A;  3EA7 A;  5C5O A;  4WY3 A;  3EAJ A;  1Q2W A;  4YOG A;  4F49 A;  3TNT A;  4WMF A;  2A5A A;  1UK3 A;  2K7X A;  2ALV A;  3VB6 A;  2Q6G A;  1WOF A;  2VJ1 A;  1UK2 A;  3VB5 A;  3SNE A;  2ZU2 A;  2HOB A;  3D62 A;  2GT7 A;  2OP9 A;  5GWZ A;  2V6N A;  3TNS A;  2Z9K A;  2Z3E A;  5B6O A;  3M3V A;  2LIZ A;  4ZUH A;  2D2D A;  3SNA A;  4WME A;  3VB7 A;  2A5K A;  3D23 A;  4YO9 A;  3IWM A;  1UJ1 A;  3TIT A;  3VB3 A;  2AMQ A;  2GZ8 A;  3AVZ A;  3F9H A;  2QIQ A;  3EBN A;  2Q6D A;  2Z9J A;  4MDS A;  5HYO A;  3E91 A;  2Z3D A;  3M3T A;  4TWW A;  2GZ9 A;  4YOI A;  1Z1I A;  4ZRO A;  1P9U A;  2C3S A;  3EA8 A;  2YNB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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