2LIZA

Nmr solution structure of c-terminal domain of sars-cov main protease in 2.5m urea
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
120
structure length
120
Chain Sequence
DRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title NMR solution structure of C-terminal domain of SARS-CoV main protease in 2.5M urea
rcsb
molecule tags Hydrolase
source organism Sars coronavirus
molecule keywords 3C-like proteinase
total genus 37
structure length 120
sequence length 120
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2011-09-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1840.10 Mainly Alpha Orthogonal Bundle main proteinase (3clpro) structure, domain 3 main proteinase (3clpro) structure, domain 3 2lizA00
4WMEA 5EU8A 2AMPA 3M3VA 2Z9GA 2QIQA 3F9HA 1Z1IA 2Z9KA 1UK4A 1UK2A 2Q6DA 2K7XA 2D2DA 4TWWA 3VB3A 3D23A 2YNBA 3AW1A 2GZ7A 4YOIA 3SNBA 2GZ8A 3F9EA 2GTBA 3V3MA 3SNCA 4ZROA 5C3NA 3M3TA 2Q6FA 3M3SA 2GZ9A 2ZU5A 3IWMA 3TIUA 5C5NA 2DUCA 3SNDA 4RSPA 5B6OA 1LVOA 3TLOA 4MDSA 3TNTA 1WOFA 4WMDA 2PWXA 1P9UA 4XFQA 2AMQA 1Q2WA 2Z94A 2QCYA 4F49A 2Z3DA 3EA7A 2GX4A 2ALVA 5C5OA 4YO9A 4YLUA 4WY3A 2VJ1A 4YOGA 3AW0A 2Z9LA 2ZU4A 3TITA 3VB5A 3EA9A 3EA8A 1UK3A 2QC2A 2V6NA 2ZU2A 2BX3A 2GT7A 4HI3A 1UJ1A 2YNAA 2LIZA 4WMFA 4TWYA 2BX4A 2HOBA 1Z1JA 3VB7A 2H2ZA 4YOJA 3TNSA 3SNEA 3VB4A 2AMDA 3EAJA 3D62A 3AVZA 3SZNA 2A5IA 2A5KA 2OP9A 2GT8A 3F9FA 3SNAA 3F9GA 4ZUHA 3E91A 1P9SA 3ATWA 2Q6GA 3SN8A 5HYOA 5GWZA 3VB6A 3EBNA 2C3SA 2Z9JA 2Z3EA 3FZDA 2A5AA 2Z3CA
chains in the Genus database with same CATH superfamily
4WMEA 5EU8A 2AMPA 3M3VA 2Z9GA 2QIQA 3F9HA 1Z1IA 2Z9KA 1UK4A 1UK2A 2Q6DA 2K7XA 2D2DA 4TWWA 3VB3A 3D23A 2YNBA 3AW1A 2GZ7A 4YOIA 3SNBA 2GZ8A 3F9EA 2GTBA 3V3MA 3SNCA 4ZROA 5C3NA 3M3TA 2Q6FA 3M3SA 2GZ9A 2ZU5A 3IWMA 3TIUA 5C5NA 2DUCA 3SNDA 4RSPA 5B6OA 1LVOA 3TLOA 4MDSA 3TNTA 1WOFA 4WMDA 2PWXA 1P9UA 4XFQA 2AMQA 1Q2WA 2Z94A 2QCYA 4F49A 2Z3DA 3EA7A 2GX4A 2ALVA 5C5OA 4YO9A 4YLUA 4WY3A 2VJ1A 4YOGA 3AW0A 2Z9LA 2ZU4A 3TITA 3VB5A 3EA9A 3EA8A 1UK3A 2QC2A 2V6NA 2ZU2A 2BX3A 2GT7A 4HI3A 1UJ1A 2YNAA 2LIZA 4WMFA 4TWYA 2BX4A 2HOBA 1Z1JA 3VB7A 2H2ZA 4YOJA 3TNSA 3SNEA 3VB4A 2AMDA 3EAJA 3D62A 3AVZA 3SZNA 2A5IA 2A5KA 2OP9A 2GT8A 3F9FA 3SNAA 3F9GA 4ZUHA 3E91A 1P9SA 3ATWA 2Q6GA 3SN8A 5HYOA 5GWZA 3VB6A 3EBNA 2C3SA 2Z9JA 2Z3EA 3FZDA 2A5AA 2Z3CA
chains in the Genus database with same CATH topology
4WMEA 5EU8A 2AMPA 3M3VA 2Z9GA 2QIQA 3F9HA 1Z1IA 2Z9KA 1UK4A 1UK2A 2Q6DA 2K7XA 2D2DA 4TWWA 3VB3A 3D23A 2YNBA 3AW1A 2GZ7A 4YOIA 3SNBA 2GZ8A 3F9EA 2GTBA 3V3MA 3SNCA 4ZROA 5C3NA 3M3TA 2Q6FA 3M3SA 2GZ9A 2ZU5A 3IWMA 3TIUA 5C5NA 2DUCA 3SNDA 4RSPA 5B6OA 1LVOA 3TLOA 4MDSA 3TNTA 1WOFA 4WMDA 2PWXA 1P9UA 4XFQA 2AMQA 1Q2WA 2Z94A 2QCYA 4F49A 2Z3DA 3EA7A 2GX4A 2ALVA 5C5OA 4YO9A 4YLUA 4WY3A 2VJ1A 4YOGA 3AW0A 2Z9LA 2ZU4A 3TITA 3VB5A 3EA9A 3EA8A 1UK3A 2QC2A 2V6NA 2ZU2A 2BX3A 2GT7A 4HI3A 1UJ1A 2YNAA 2LIZA 4WMFA 4TWYA 2BX4A 2HOBA 1Z1JA 3VB7A 2H2ZA 4YOJA 3TNSA 3SNEA 3VB4A 2AMDA 3EAJA 3D62A 3AVZA 3SZNA 2A5IA 2A5KA 2OP9A 2GT8A 3F9FA 3SNAA 3F9GA 4ZUHA 3E91A 1P9SA 3ATWA 2Q6GA 3SN8A 5HYOA 5GWZA 3VB6A 3EBNA 2C3SA 2Z9JA 2Z3EA 3FZDA 2A5AA 2Z3CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WME A;  5EU8 A;  2AMP A;  3M3V A;  2Z9G A;  2QIQ A;  3F9H A;  1Z1I A;  2Z9K A;  1UK4 A;  1UK2 A;  2Q6D A;  2K7X A;  2D2D A;  4TWW A;  3VB3 A;  3D23 A;  2YNB A;  3AW1 A;  2GZ7 A;  4YOI A;  3SNB A;  2GZ8 A;  3F9E A;  2GTB A;  3V3M A;  3SNC A;  4ZRO A;  5C3N A;  3M3T A;  2Q6F A;  3M3S A;  2GZ9 A;  2ZU5 A;  3IWM A;  3TIU A;  5C5N A;  2DUC A;  3SND A;  4RSP A;  5B6O A;  1LVO A;  3TLO A;  4MDS A;  3TNT A;  1WOF A;  4WMD A;  2PWX A;  1P9U A;  4XFQ A;  2AMQ A;  1Q2W A;  2Z94 A;  2QCY A;  4F49 A;  2Z3D A;  3EA7 A;  2GX4 A;  2ALV A;  5C5O A;  4YO9 A;  4YLU A;  4WY3 A;  2VJ1 A;  4YOG A;  3AW0 A;  2Z9L A;  2ZU4 A;  3TIT A;  3VB5 A;  3EA9 A;  3EA8 A;  1UK3 A;  2QC2 A;  2V6N A;  2ZU2 A;  2BX3 A;  2GT7 A;  4HI3 A;  1UJ1 A;  2YNA A;  2LIZ A;  4WMF A;  4TWY A;  2BX4 A;  2HOB A;  1Z1J A;  3VB7 A;  2H2Z A;  4YOJ A;  3TNS A;  3SNE A;  3VB4 A;  2AMD A;  3EAJ A;  3D62 A;  3AVZ A;  3SZN A;  2A5I A;  2A5K A;  2OP9 A;  2GT8 A;  3F9F A;  3SNA A;  3F9G A;  4ZUH A;  3E91 A;  1P9S A;  3ATW A;  2Q6G A;  3SN8 A;  5HYO A;  5GWZ A;  3VB6 A;  3EBN A;  2C3S A;  2Z9J A;  2Z3E A;  3FZD A;  2A5A A;  2Z3C A; 
#chains in the Genus database with same CATH topology
 4WME A;  5EU8 A;  2AMP A;  3M3V A;  2Z9G A;  2QIQ A;  3F9H A;  1Z1I A;  2Z9K A;  1UK4 A;  1UK2 A;  2Q6D A;  2K7X A;  2D2D A;  4TWW A;  3VB3 A;  3D23 A;  2YNB A;  3AW1 A;  2GZ7 A;  4YOI A;  3SNB A;  2GZ8 A;  3F9E A;  2GTB A;  3V3M A;  3SNC A;  4ZRO A;  5C3N A;  3M3T A;  2Q6F A;  3M3S A;  2GZ9 A;  2ZU5 A;  3IWM A;  3TIU A;  5C5N A;  2DUC A;  3SND A;  4RSP A;  5B6O A;  1LVO A;  3TLO A;  4MDS A;  3TNT A;  1WOF A;  4WMD A;  2PWX A;  1P9U A;  4XFQ A;  2AMQ A;  1Q2W A;  2Z94 A;  2QCY A;  4F49 A;  2Z3D A;  3EA7 A;  2GX4 A;  2ALV A;  5C5O A;  4YO9 A;  4YLU A;  4WY3 A;  2VJ1 A;  4YOG A;  3AW0 A;  2Z9L A;  2ZU4 A;  3TIT A;  3VB5 A;  3EA9 A;  3EA8 A;  1UK3 A;  2QC2 A;  2V6N A;  2ZU2 A;  2BX3 A;  2GT7 A;  4HI3 A;  1UJ1 A;  2YNA A;  2LIZ A;  4WMF A;  4TWY A;  2BX4 A;  2HOB A;  1Z1J A;  3VB7 A;  2H2Z A;  4YOJ A;  3TNS A;  3SNE A;  3VB4 A;  2AMD A;  3EAJ A;  3D62 A;  3AVZ A;  3SZN A;  2A5I A;  2A5K A;  2OP9 A;  2GT8 A;  3F9F A;  3SNA A;  3F9G A;  4ZUH A;  3E91 A;  1P9S A;  3ATW A;  2Q6G A;  3SN8 A;  5HYO A;  5GWZ A;  3VB6 A;  3EBN A;  2C3S A;  2Z9J A;  2Z3E A;  3FZD A;  2A5A A;  2Z3C A; 
#chains in the Genus database with same CATH homology
 4WME A;  5EU8 A;  2AMP A;  3M3V A;  2Z9G A;  2QIQ A;  3F9H A;  1Z1I A;  2Z9K A;  1UK4 A;  1UK2 A;  2Q6D A;  2K7X A;  2D2D A;  4TWW A;  3VB3 A;  3D23 A;  2YNB A;  3AW1 A;  2GZ7 A;  4YOI A;  3SNB A;  2GZ8 A;  3F9E A;  2GTB A;  3V3M A;  3SNC A;  4ZRO A;  5C3N A;  3M3T A;  2Q6F A;  3M3S A;  2GZ9 A;  2ZU5 A;  3IWM A;  3TIU A;  5C5N A;  2DUC A;  3SND A;  4RSP A;  5B6O A;  1LVO A;  3TLO A;  4MDS A;  3TNT A;  1WOF A;  4WMD A;  2PWX A;  1P9U A;  4XFQ A;  2AMQ A;  1Q2W A;  2Z94 A;  2QCY A;  4F49 A;  2Z3D A;  3EA7 A;  2GX4 A;  2ALV A;  5C5O A;  4YO9 A;  4YLU A;  4WY3 A;  2VJ1 A;  4YOG A;  3AW0 A;  2Z9L A;  2ZU4 A;  3TIT A;  3VB5 A;  3EA9 A;  3EA8 A;  1UK3 A;  2QC2 A;  2V6N A;  2ZU2 A;  2BX3 A;  2GT7 A;  4HI3 A;  1UJ1 A;  2YNA A;  2LIZ A;  4WMF A;  4TWY A;  2BX4 A;  2HOB A;  1Z1J A;  3VB7 A;  2H2Z A;  4YOJ A;  3TNS A;  3SNE A;  3VB4 A;  2AMD A;  3EAJ A;  3D62 A;  3AVZ A;  3SZN A;  2A5I A;  2A5K A;  2OP9 A;  2GT8 A;  3F9F A;  3SNA A;  3F9G A;  4ZUH A;  3E91 A;  1P9S A;  3ATW A;  2Q6G A;  3SN8 A;  5HYO A;  5GWZ A;  3VB6 A;  3EBN A;  2C3S A;  2Z9J A;  2Z3E A;  3FZD A;  2A5A A;  2Z3C A; 
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similar chains in the Genus database (?% sequence similarity)
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