2P95L

Factor xa in complex with the inhibitor 5-chloro-n-((1r,2s)-2-(4-(2-oxopyridin-1(2h)-yl)benzamido) cyclopentyl)thiophene-2-carboxamide
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Factor Xa
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2p95L00
3HS7A 3M36L 3FCSB 4O1ZA 1IGZA 2EI8B 1W8BL 2VWLL 1EZQB 2W86A 1W7XL 5JBCE 5CKQA 3LTFB 4BXSA 4BXWA 4JZDL 2KB9A 1NFWB 2M74A 1YUGA 3N8WA 3HO5A 3Q7DA 2VVCK 2W2QE 3NTGA 4X8TL 1G1SA 5CISA 1ATDA 2B7DL 2YGPA 4ZAEB 2MGRA 1G2MB 3H5CB 3GCWE 3EGFA 1TOZA 4ISHL 4YT7L 4TGFA 2FLGA 1CVUA 5IKVA 1IJQA 1ATEA 1LPGA 1UZPA 3SOQA 2D1JB 5L2YL 2AYLA 2W26B 1EPHA 2W2OE 1HT5A 4Y6DB 2UWOB 2Y5HL 1WU1B 5KN5C 4NG9L 2WYGB 4CSYA 1UZKA 4Z0LA 5L2ZL 3N8WB 1N7DA 1LPZA 2OYEP 1EPGA 3N8YB 3NTBA 3N8ZA 3CA7A 4G1MB 4RRWA 2BO2A 3SW2A 2W2ME 1EQGA 2J95B 3V64C 5JBBE 2J4IB 1U8CB 2K2TA 3BT1A 5JW1A 2P28B 1NPEB 4X8SL 3KQCL 1HREA 1TPGA 1CCFA 1ATAA 1APOA 1DVAL 2XBXL 2Y5FL 4LORA 4BTTA 1YGCL 4Z6AL 4XLWA 4LMFA 4ZXYL 1IQKL 2VWMK 3FFGL 3F6UL 4FM5A 1CQEA 1CX2A 1N1IA 4BDXA 2PUQL 3QMOA 4JYVL 1AUTL 4Y71B 2WG4B 4XBMA 1HRFA 1ADXA 1KLOA 2WG3C 3HPTA 2J38B 1JL9A 2WPKE 4RUTA 1NT0A 1DX5I 2KL7A 2Y82B 3LC5B 4O02B 6COXA 4Y76B 1Z6EL 5L30L 2PHBB 1IOEL 1COUA 2BMGA 1NFYB 2W2NE 1NFXB 1WHEA 4C16A 5K0HB 3ZYGA 2Y38A 3P5BL 2UWPB 1LQDA 3QH0A 5KIRA 3KRKA 1G1TA 1EAIC 1WHFA 4JZFL 2H9EL 1IQHL 3CS7L 4COXA 4CUDA 3OLTA 5JBAE 1P0SL 4RRXA 2WFTA 1ATBA 2UWLB 4M11A 2P95L 5EGMB 1DQBA 2I9AA 4PH9A 2Y7ZB 1PGEA 3ZYIB 1NQLB 4X8UL 1J9CL 1IP0A 3GISX 2FLBL 1FAKL 1IQNL 2K2SB 2VVVL 1K36A 2WFXB 2RHPA 1KLIL 1EPJA 3MDLA 4BTIA 2WPME 4BDWA 4JZEL 2XC0L 3TK6B 3RR3A 1L5GB 1FF7A 1YUKB 1SZBA 3IJEB 3LAQA 3M37L 5E8DA 3F1SB 1IQFL 1HT8A 1IVOC 4CUFA 5JVYA 3KQBL 1HCGB 2XC4L 1PTHA 3R05A 1CVWL 1L3YA 1JBUL 2VWNL 2VWOL 4RRZA 2YGOA 1XKAL 1I0UA 3TK5B 2BOUA 2FLRL 1YO8A 1A3PA 3GCXE 2FD6A 2BQWA 1LMJA 1GK5A 1MOXC 2VH6B 3LN1A 2W3IB 1QFKL 1APQA 3ELAL 3FBYA 3U73A 2CJIB 2MHPA 1HZ8A 1RFNB 1F0RB 1TLEA 1M1XB 1IGXA 4RS0A 4E1GA 2WPJE 2EI7B 4NGAL 5CKNA 1FAXL 1DIYA 1DDXA 1EMNA 1G1RA 1IQLL 3N8VA 3HO3A 3SOBB 3KQDL 1V3XB 3IITB 1IOXA 2P3TA 2OYUP 3HS5A 1EMOA 1IQJL 1KSNB 4MMYB 1G2LB 1IQIL 4A7IA 1FFMA 2XBWL 1XDTR 2BOXA 1CEJA 4M10A 1BF9A 3C9AC 4ZXXL 1IQGL 2Y7XB 3KK6A 1PRHA 2J34B 1IQML 1B9WA 4D0EA 2PR3B 2XBVL 2TGFA 1XKBA 2BOKL 1EGFA 2FZZL 4D0FA 2G00L 2GD4A 1EQHA 1MQ5L 1ZAQA 3PGHA 5IKTA 2DDUA 1G1QA 3CFWA 1HAEA 4CUEA 4Y79B 3ZYJB 2Y5GL 2XC5L 1C5MF 1FJSL 2Q1JB 1O5DL 3N8YA 4AQTA 2J94B 5FDQA 3N8XA 2Y80B 4YT6L 2BZ6L 4X8VL 4NA9L 1X7AL 3TZIA 1F7EA 3ENSA 4Z0KB 2RA0L 1NFUB 4JYUL 2P3FN 5CKMA 3HS6A 1KLJL 4Y7AB 2NPRA 1EPIA 3K9XA 2JKHL 1LPKA 3OLUA 1PXXA 2J2UB 1NZIA 1OB1C 1IQEL 1P9JA 1JV2B 1MQ6L 1K37A 2BQ7A 4YZUB 1F0SB 3V65B 2P16L 1CCVA 5IKQA 2W2PE 3POYA 2VH0B 3U7UG 2VJ3A 1HX2A 3LN0A 4BTUA 1URKA 5COXA 1YUFA 1PFXL 3NT1A 3TBDA 4ZHAB 3KQEL 3LIWB 1FSBA 2P93L 3QCWA 1Q4GA 2P26A 1KIGL 3BPSE 2W3KB 3SOVA 3NJPC 4OTYA 2KV4A 5JB8E 3KCGL 1HAFA 2RNLA 5JB9E 2WPHE 2WPLE 2ADXA 3MQEA 1F7MA 1FE2A 3LC3B 4MMXB 5I46L 4Y7BB 1EBVA 5F19A 4OTJA 2MGPA 2BOHA 2P94L 5IKRA 2EI6B 2VVUL 4ZH8B 3DEMA 3KL6B 1UZJA 2P3FL 3TGFA 2Y81B 1Z6CA 1HJ7A 1UZQA 4MMZB 1U67A 1XFEA 2XBYL 3TH3L 3CENL 5F1AA 3ASIA 4RRYA 2I9BA 4D90A 2BQ6A 3BT2A 4XL1A 5JVZA 4ISIL 2F9BL 3LTGD 2WYJB 3HO4A 2P3UA 2WPIE 3Q3KB
chains in the Genus database with same CATH superfamily
3HS7A 3M36L 3FCSB 4O1ZA 1IGZA 2EI8B 1W8BL 2VWLL 1EZQB 2W86A 1W7XL 5JBCE 5CKQA 3LTFB 4BXSA 4BXWA 4JZDL 2KB9A 1NFWB 2M74A 1YUGA 3N8WA 3HO5A 3Q7DA 2VVCK 2W2QE 3NTGA 4X8TL 1G1SA 5CISA 1ATDA 2B7DL 2YGPA 4ZAEB 2MGRA 1G2MB 3H5CB 3GCWE 4GU3A 3EGFA 1TOZA 4ISHL 4YT7L 4TGFA 2FLGA 1CVUA 5IKVA 1IJQA 1ATEA 1LPGA 1UZPA 3SOQA 2D1JB 5L2YL 2AYLA 2W26B 1EPHA 2W2OE 1HT5A 4Y6DB 2UWOB 2Y5HL 1WU1B 5KN5C 1LK9A 4NG9L 2WYGB 4CSYA 1UZKA 4Z0LA 5L2ZL 3N8WB 1N7DA 1LPZA 4A94C 2OYEP 1EPGA 3N8YB 3NTBA 3N8ZA 3CA7A 4G1MB 4RRWA 2BO2A 3SW2A 2W2ME 1EQGA 2J95B 3V64C 5JBBE 2J4IB 1U8CB 2K2TA 3BT1A 5JW1A 2P28B 1NPEB 4X8SL 3KQCL 1HREA 1TPGA 1KKEA 1V1IA 1CCFA 1ATAA 1APOA 1DVAL 2XBXL 2Y5FL 4LORA 4BTTA 1YGCL 4Z6AL 4XLWA 4LMFA 2VRSA 4ZXYL 1IQKL 2VWMK 3FFGL 3F6UL 4FM5A 1CQEA 1CX2A 1N1IA 4BDXA 2PUQL 3QMOA 4JYVL 1AUTL 4Y71B 2WG4B 4XBMA 1HRFA 1ADXA 1KLOA 2WG3C 3HPTA 2J38B 1JL9A 2WPKE 4RUTA 1NT0A 1DX5I 2KL7A 2Y82B 3LC5B 4O02B 6COXA 4Y76B 1Z6EL 5L30L 2PHBB 1IOEL 1COUA 2BMGA 1NFYB 2W2NE 1NFXB 1WHEA 4C16A 5K0HB 3ZYGA 2Y38A 3P5BL 2UWPB 1LQDA 3QH0A 5KIRA 2HOXA 3KRKA 1G1TA 1EAIC 1WHFA 4JZFL 2H9EL 1IQHL 3CS7L 4COXA 4CUDA 3OLTA 5JBAE 1P0SL 4RRXA 2WFTA 1ATBA 2UWLB 4M11A 2P95L 5EGMB 1DQBA 2I9AA 4PH9A 2Y7ZB 2BT8A 1PGEA 3ZYIB 1NQLB 4X8UL 1J9CL 1IP0A 3GISX 2FLBL 1FAKL 1IQNL 2K2SB 2VVVL 1K36A 2WFXB 2RHPA 1KLIL 1EPJA 3MDLA 4BTIA 2WPME 4BDWA 4JZEL 2XC0L 3TK6B 3RR3A 1L5GB 1FF7A 1YUKB 1SZBA 3IJEB 3LAQA 3M37L 5E8DA 3F1SB 1IQFL 1HT8A 1IVOC 4CUFA 5JVYA 3KQBL 1HCGB 2XC4L 1PTHA 3R05A 1CVWL 1L3YA 1JBUL 2VWNL 2VWOL 4RRZA 2YGOA 1XKAL 1I0UA 2BT7A 3TK5B 2BOUA 2FLRL 1YO8A 1A3PA 3GCXE 2FD6A 2BQWA 1LMJA 1GK5A 1MOXC 2VH6B 3LN1A 2W3IB 1QFKL 1APQA 3ELAL 3FBYA 3U73A 2CJIB 2MHPA 1HZ8A 1RFNB 1F0RB 1TLEA 1M1XB 1QIUA 1IGXA 4RS0A 2H9EC 4E1GA 4GU4A 2HORA 2WPJE 2EI7B 4NGAL 5CKNA 1FAXL 1DIYA 1DDXA 1EMNA 1G1RA 1IQLL 3N8VA 3HO3A 3SOBB 3KQDL 1V3XB 3IITB 1IOXA 2P3TA 2OYUP 3HS5A 1EMOA 1IQJL 1KSNB 2WZPP 4MMYB 1G2LB 1IQIL 4A7IA 1FFMA 2XBWL 1XDTR 2BOXA 1CEJA 4M10A 1BF9A 3C9AC 4ZXXL 1IQGL 2Y7XB 3KK6A 1PRHA 2J34B 1IQML 1B9WA 4D0EA 2PR3B 2XBVL 2TGFA 1XKBA 2BOKL 1EGFA 2FZZL 2YGQA 4D0FA 2G00L 2GD4A 1EQHA 1MQ5L 1ZAQA 3PGHA 5IKTA 2DDUA 1G1QA 3CFWA 1HAEA 4CUEA 4Y79B 3ZYJB 2Y5GL 2XC5L 1C5MF 1FJSL 2Q1JB 1O5DL 2JJLA 3N8YA 4AQTA 2J94B 5FDQA 3N8XA 2Y80B 4YT6L 2BZ6L 4X8VL 4NA9L 1X7AL 3TZIA 1F7EA 3ENSA 4Z0KB 2RA0L 1NFUB 4JYUL 2P3FN 5CKMA 3HS6A 1KLJL 4Y7AB 2NPRA 1EPIA 3K9XA 2JKHL 1LPKA 3OLUA 1PXXA 2J2UB 1NZIA 1OB1C 1IQEL 1P9JA 1JV2B 1MQ6L 1K37A 2BQ7A 4YZUB 1F0SB 3V65B 2P16L 1CCVA 5IKQA 2W2PE 3POYA 2VH0B 3U7UG 2VJ3A 1HX2A 3LN0A 1LMMA 4BTUA 1URKA 5COXA 1YUFA 1PFXL 3NT1A 3TBDA 4ZHAB 3KQEL 3LIWB 1FSBA 2P93L 3QCWA 1Q4GA 2P26A 1KIGL 3BPSE 2W3KB 3SOVA 3NJPC 2BSFA 4OTYA 2KV4A 5JB8E 3KCGL 1HAFA 2RNLA 5JB9E 1V1HA 2WPHE 2WPLE 2ADXA 3MQEA 1F7MA 1FE2A 3LC3B 4MMXB 5I46L 4Y7BB 1EBVA 5F19A 4OTJA 2MGPA 2BOHA 2P94L 5IKRA 2EI6B 2VVUL 4ZH8B 3DEMA 3KL6B 1UZJA 2P3FL 3TGFA 2Y81B 1Z6CA 1HJ7A 1UZQA 4MMZB 1U67A 1XFEA 2XBYL 3TH3L 3CENL 5F1AA 3ASIA 4RRYA 2I9BA 4D90A 2BQ6A 3BT2A 4XL1A 5JVZA 4ISIL 2F9BL 3LTGD 2WYJB 3HO4A 2KNIA 2P3UA 3S6XA 2WPIE 3Q3KB
chains in the Genus database with same CATH topology
3HS7A 3M36L 3FCSB 4O1ZA 1IGZA 2EI8B 1W8BL 2VWLL 1EZQB 2W86A 1W7XL 5JBCE 5CKQA 3LTFB 4BXSA 4BXWA 4JZDL 2KB9A 1NFWB 2M74A 1YUGA 3N8WA 3HO5A 3Q7DA 2VVCK 2W2QE 3NTGA 4X8TL 1G1SA 5CISA 1ATDA 2B7DL 2YGPA 4ZAEB 2MGRA 1G2MB 3H5CB 3GCWE 3EGFA 1TOZA 4ISHL 4YT7L 4TGFA 2FLGA 1CVUA 5IKVA 1IJQA 1ATEA 1LPGA 1UZPA 3SOQA 2D1JB 5L2YL 2AYLA 2W26B 1EPHA 2W2OE 1HT5A 4Y6DB 2UWOB 2Y5HL 1WU1B 5KN5C 4NG9L 2WYGB 4CSYA 1UZKA 4Z0LA 5L2ZL 3N8WB 1N7DA 1LPZA 4A94C 2OYEP 1EPGA 3N8YB 3NTBA 3N8ZA 3CA7A 4G1MB 4RRWA 2BO2A 3SW2A 2W2ME 1EQGA 2J95B 3V64C 5JBBE 2J4IB 1U8CB 2K2TA 3BT1A 5JW1A 2P28B 1NPEB 4X8SL 3KQCL 1HREA 1TPGA 1CCFA 1ATAA 1APOA 1DVAL 2XBXL 2Y5FL 4LORA 4BTTA 1YGCL 4Z6AL 4XLWA 4LMFA 4ZXYL 1IQKL 2VWMK 3FFGL 3F6UL 4FM5A 1CQEA 1CX2A 1N1IA 4BDXA 2PUQL 3QMOA 4JYVL 1AUTL 4Y71B 2WG4B 4XBMA 1HRFA 1ADXA 1KLOA 2WG3C 3HPTA 2J38B 1JL9A 2WPKE 4RUTA 1NT0A 1DX5I 2KL7A 2Y82B 3LC5B 4O02B 6COXA 4Y76B 1Z6EL 5L30L 2PHBB 1IOEL 1COUA 2BMGA 1NFYB 2W2NE 1NFXB 1WHEA 4C16A 5K0HB 3ZYGA 2Y38A 3P5BL 2UWPB 1LQDA 3QH0A 5KIRA 3KRKA 1G1TA 1EAIC 1WHFA 4JZFL 2H9EL 1IQHL 3CS7L 4COXA 4CUDA 3OLTA 5JBAE 1P0SL 4RRXA 2WFTA 1ATBA 2UWLB 4M11A 2P95L 5EGMB 1DQBA 2I9AA 4PH9A 2Y7ZB 1PGEA 3ZYIB 1NQLB 4X8UL 1J9CL 1IP0A 3GISX 2FLBL 1FAKL 1IQNL 2K2SB 2VVVL 1K36A 2WFXB 2RHPA 1KLIL 1EPJA 3MDLA 4BTIA 2WPME 4BDWA 4JZEL 2XC0L 3TK6B 3RR3A 1L5GB 1FF7A 1YUKB 1SZBA 3IJEB 3LAQA 3M37L 5E8DA 3F1SB 1IQFL 1HT8A 1IVOC 4CUFA 5JVYA 3KQBL 1HCGB 2XC4L 1PTHA 3R05A 1CVWL 1L3YA 1JBUL 2VWNL 2VWOL 4RRZA 2YGOA 1XKAL 1I0UA 3TK5B 2BOUA 2FLRL 1YO8A 1A3PA 3GCXE 2FD6A 2BQWA 1LMJA 1GK5A 1MOXC 2VH6B 3LN1A 2W3IB 1QFKL 1APQA 3ELAL 3FBYA 3U73A 2CJIB 2MHPA 1HZ8A 1RFNB 1F0RB 1TLEA 1M1XB 1IGXA 4RS0A 2H9EC 4E1GA 2WPJE 2EI7B 4NGAL 5CKNA 1FAXL 1DIYA 1DDXA 1EMNA 1G1RA 1IQLL 3N8VA 3HO3A 3SOBB 3KQDL 1V3XB 3IITB 1IOXA 2P3TA 2OYUP 3HS5A 1EMOA 1IQJL 1KSNB 2WZPP 4MMYB 1G2LB 1IQIL 4A7IA 1FFMA 2XBWL 1XDTR 2BOXA 1CEJA 4M10A 1BF9A 3C9AC 4ZXXL 1IQGL 2Y7XB 3KK6A 1PRHA 2J34B 1IQML 1B9WA 4D0EA 2PR3B 2XBVL 2TGFA 1XKBA 2BOKL 1EGFA 2FZZL 2YGQA 4D0FA 2G00L 2GD4A 1EQHA 1MQ5L 1ZAQA 3PGHA 5IKTA 2DDUA 1G1QA 3CFWA 1HAEA 4CUEA 4Y79B 3ZYJB 2Y5GL 2XC5L 1C5MF 1FJSL 2Q1JB 1O5DL 3N8YA 4AQTA 2J94B 5FDQA 3N8XA 2Y80B 4YT6L 2BZ6L 4X8VL 4NA9L 1X7AL 3TZIA 1F7EA 3ENSA 4Z0KB 2RA0L 1NFUB 4JYUL 2P3FN 5CKMA 3HS6A 1KLJL 4Y7AB 2NPRA 1EPIA 3K9XA 2JKHL 1LPKA 3OLUA 1PXXA 2J2UB 1NZIA 1OB1C 1IQEL 1P9JA 1JV2B 1MQ6L 1K37A 2BQ7A 4YZUB 1F0SB 3V65B 2P16L 1CCVA 5IKQA 2W2PE 3POYA 2VH0B 3U7UG 2VJ3A 1HX2A 3LN0A 1LMMA 4BTUA 1URKA 5COXA 1YUFA 1PFXL 3NT1A 3TBDA 4ZHAB 3KQEL 3LIWB 1FSBA 2P93L 3QCWA 1Q4GA 2P26A 1KIGL 3BPSE 2W3KB 3SOVA 3NJPC 4OTYA 2KV4A 5JB8E 3KCGL 1HAFA 2RNLA 5JB9E 2WPHE 2WPLE 2ADXA 3MQEA 1F7MA 1FE2A 3LC3B 4MMXB 5I46L 4Y7BB 1EBVA 5F19A 4OTJA 2MGPA 2BOHA 2P94L 5IKRA 2EI6B 2VVUL 4ZH8B 3DEMA 3KL6B 1UZJA 2P3FL 3TGFA 2Y81B 1Z6CA 1HJ7A 1UZQA 4MMZB 1U67A 1XFEA 2XBYL 3TH3L 3CENL 5F1AA 3ASIA 4RRYA 2I9BA 4D90A 2BQ6A 3BT2A 4XL1A 5JVZA 4ISIL 2F9BL 3LTGD 2WYJB 3HO4A 2KNIA 2P3UA 3S6XA 2WPIE 3Q3KB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HS7 A;  3M36 L;  3FCS B;  4O1Z A;  1IGZ A;  2EI8 B;  1W8B L;  2VWL L;  1EZQ B;  2W86 A;  1W7X L;  5JBC E;  5CKQ A;  3LTF B;  4BXS A;  4BXW A;  4JZD L;  2KB9 A;  1NFW B;  2M74 A;  1YUG A;  3N8W A;  3HO5 A;  3Q7D A;  2VVC K;  2W2Q E;  3NTG A;  4X8T L;  1G1S A;  5CIS A;  1ATD A;  2B7D L;  2YGP A;  4ZAE B;  2MGR A;  1G2M B;  3H5C B;  3GCW E;  3EGF A;  1TOZ A;  4ISH L;  4YT7 L;  4TGF A;  2FLG A;  1CVU A;  5IKV A;  1IJQ A;  1ATE A;  1LPG A;  1UZP A;  3SOQ A;  2D1J B;  5L2Y L;  2AYL A;  2W26 B;  1EPH A;  2W2O E;  1HT5 A;  4Y6D B;  2UWO B;  2Y5H L;  1WU1 B;  5KN5 C;  4NG9 L;  2WYG B;  4CSY A;  1UZK A;  4Z0L A;  5L2Z L;  3N8W B;  1N7D A;  1LPZ A;  2OYE P;  1EPG A;  3N8Y B;  3NTB A;  3N8Z A;  3CA7 A;  4G1M B;  4RRW A;  2BO2 A;  3SW2 A;  2W2M E;  1EQG A;  2J95 B;  3V64 C;  5JBB E;  2J4I B;  1U8C B;  2K2T A;  3BT1 A;  5JW1 A;  2P28 B;  1NPE B;  4X8S L;  3KQC L;  1HRE A;  1TPG A;  1CCF A;  1ATA A;  1APO A;  1DVA L;  2XBX L;  2Y5F L;  4LOR A;  4BTT A;  1YGC L;  4Z6A L;  4XLW A;  4LMF A;  4ZXY L;  1IQK L;  2VWM K;  3FFG L;  3F6U L;  4FM5 A;  1CQE A;  1CX2 A;  1N1I A;  4BDX A;  2PUQ L;  3QMO A;  4JYV L;  1AUT L;  4Y71 B;  2WG4 B;  4XBM A;  1HRF A;  1ADX A;  1KLO A;  2WG3 C;  3HPT A;  2J38 B;  1JL9 A;  2WPK E;  4RUT A;  1NT0 A;  1DX5 I;  2KL7 A;  2Y82 B;  3LC5 B;  4O02 B;  6COX A;  4Y76 B;  1Z6E L;  5L30 L;  2PHB B;  1IOE L;  1COU A;  2BMG A;  1NFY B;  2W2N E;  1NFX B;  1WHE A;  4C16 A;  5K0H B;  3ZYG A;  2Y38 A;  3P5B L;  2UWP B;  1LQD A;  3QH0 A;  5KIR A;  3KRK A;  1G1T A;  1EAI C;  1WHF A;  4JZF L;  2H9E L;  1IQH L;  3CS7 L;  4COX A;  4CUD A;  3OLT A;  5JBA E;  1P0S L;  4RRX A;  2WFT A;  1ATB A;  2UWL B;  4M11 A;  2P95 L;  5EGM B;  1DQB A;  2I9A A;  4PH9 A;  2Y7Z B;  1PGE A;  3ZYI B;  1NQL B;  4X8U L;  1J9C L;  1IP0 A;  3GIS X;  2FLB L;  1FAK L;  1IQN L;  2K2S B;  2VVV L;  1K36 A;  2WFX B;  2RHP A;  1KLI L;  1EPJ A;  3MDL A;  4BTI A;  2WPM E;  4BDW A;  4JZE L;  2XC0 L;  3TK6 B;  3RR3 A;  1L5G B;  1FF7 A;  1YUK B;  1SZB A;  3IJE B;  3LAQ A;  3M37 L;  5E8D A;  3F1S B;  1IQF L;  1HT8 A;  1IVO C;  4CUF A;  5JVY A;  3KQB L;  1HCG B;  2XC4 L;  1PTH A;  3R05 A;  1CVW L;  1L3Y A;  1JBU L;  2VWN L;  2VWO L;  4RRZ A;  2YGO A;  1XKA L;  1I0U A;  3TK5 B;  2BOU A;  2FLR L;  1YO8 A;  1A3P A;  3GCX E;  2FD6 A;  2BQW A;  1LMJ A;  1GK5 A;  1MOX C;  2VH6 B;  3LN1 A;  2W3I B;  1QFK L;  1APQ A;  3ELA L;  3FBY A;  3U73 A;  2CJI B;  2MHP A;  1HZ8 A;  1RFN B;  1F0R B;  1TLE A;  1M1X B;  1IGX A;  4RS0 A;  4E1G A;  2WPJ E;  2EI7 B;  4NGA L;  5CKN A;  1FAX L;  1DIY A;  1DDX A;  1EMN A;  1G1R A;  1IQL L;  3N8V A;  3HO3 A;  3SOB B;  3KQD L;  1V3X B;  3IIT B;  1IOX A;  2P3T A;  2OYU P;  3HS5 A;  1EMO A;  1IQJ L;  1KSN B;  4MMY B;  1G2L B;  1IQI L;  4A7I A;  1FFM A;  2XBW L;  1XDT R;  2BOX A;  1CEJ A;  4M10 A;  1BF9 A;  3C9A C;  4ZXX L;  1IQG L;  2Y7X B;  3KK6 A;  1PRH A;  2J34 B;  1IQM L;  1B9W A;  4D0E A;  2PR3 B;  2XBV L;  2TGF A;  1XKB A;  2BOK L;  1EGF A;  2FZZ L;  4D0F A;  2G00 L;  2GD4 A;  1EQH A;  1MQ5 L;  1ZAQ A;  3PGH A;  5IKT A;  2DDU A;  1G1Q A;  3CFW A;  1HAE A;  4CUE A;  4Y79 B;  3ZYJ B;  2Y5G L;  2XC5 L;  1C5M F;  1FJS L;  2Q1J B;  1O5D L;  3N8Y A;  4AQT A;  2J94 B;  5FDQ A;  3N8X A;  2Y80 B;  4YT6 L;  2BZ6 L;  4X8V L;  4NA9 L;  1X7A L;  3TZI A;  1F7E A;  3ENS A;  4Z0K B;  2RA0 L;  1NFU B;  4JYU L;  2P3F N;  5CKM A;  3HS6 A;  1KLJ L;  4Y7A B;  2NPR A;  1EPI A;  3K9X A;  2JKH L;  1LPK A;  3OLU A;  1PXX A;  2J2U B;  1NZI A;  1OB1 C;  1IQE L;  1P9J A;  1JV2 B;  1MQ6 L;  1K37 A;  2BQ7 A;  4YZU B;  1F0S B;  3V65 B;  2P16 L;  1CCV A;  5IKQ A;  2W2P E;  3POY A;  2VH0 B;  3U7U G;  2VJ3 A;  1HX2 A;  3LN0 A;  4BTU A;  1URK A;  5COX A;  1YUF A;  1PFX L;  3NT1 A;  3TBD A;  4ZHA B;  3KQE L;  3LIW B;  1FSB A;  2P93 L;  3QCW A;  1Q4G A;  2P26 A;  1KIG L;  3BPS E;  2W3K B;  3SOV A;  3NJP C;  4OTY A;  2KV4 A;  5JB8 E;  3KCG L;  1HAF A;  2RNL A;  5JB9 E;  2WPH E;  2WPL E;  2ADX A;  3MQE A;  1F7M A;  1FE2 A;  3LC3 B;  4MMX B;  5I46 L;  4Y7B B;  1EBV A;  5F19 A;  4OTJ A;  2MGP A;  2BOH A;  2P94 L;  5IKR A;  2EI6 B;  2VVU L;  4ZH8 B;  3DEM A;  3KL6 B;  1UZJ A;  2P3F L;  3TGF A;  2Y81 B;  1Z6C A;  1HJ7 A;  1UZQ A;  4MMZ B;  1U67 A;  1XFE A;  2XBY L;  3TH3 L;  3CEN L;  5F1A A;  3ASI A;  4RRY A;  2I9B A;  4D90 A;  2BQ6 A;  3BT2 A;  4XL1 A;  5JVZ A;  4ISI L;  2F9B L;  3LTG D;  2WYJ B;  3HO4 A;  2P3U A;  2WPI E;  3Q3K B; 
#chains in the Genus database with same CATH topology
 3HS7 A;  3M36 L;  3FCS B;  4O1Z A;  1IGZ A;  2EI8 B;  1W8B L;  2VWL L;  1EZQ B;  2W86 A;  1W7X L;  5JBC E;  5CKQ A;  3LTF B;  4BXS A;  4BXW A;  4JZD L;  2KB9 A;  1NFW B;  2M74 A;  1YUG A;  3N8W A;  3HO5 A;  3Q7D A;  2VVC K;  2W2Q E;  3NTG A;  4X8T L;  1G1S A;  5CIS A;  1ATD A;  2B7D L;  2YGP A;  4ZAE B;  2MGR A;  1G2M B;  3H5C B;  3GCW E;  4GU3 A;  3EGF A;  1TOZ A;  4ISH L;  4YT7 L;  4TGF A;  2FLG A;  1CVU A;  5IKV A;  1IJQ A;  1ATE A;  1LPG A;  1UZP A;  3SOQ A;  2D1J B;  5L2Y L;  2AYL A;  2W26 B;  1EPH A;  2W2O E;  1HT5 A;  4Y6D B;  2UWO B;  2Y5H L;  1WU1 B;  5KN5 C;  1LK9 A;  4NG9 L;  2WYG B;  4CSY A;  1UZK A;  4Z0L A;  5L2Z L;  3N8W B;  1N7D A;  1LPZ A;  4A94 C;  2OYE P;  1EPG A;  3N8Y B;  3NTB A;  3N8Z A;  3CA7 A;  4G1M B;  4RRW A;  2BO2 A;  3SW2 A;  2W2M E;  1EQG A;  2J95 B;  3V64 C;  5JBB E;  2J4I B;  1U8C B;  2K2T A;  3BT1 A;  5JW1 A;  2P28 B;  1NPE B;  4X8S L;  3KQC L;  1HRE A;  1TPG A;  1KKE A;  1V1I A;  1CCF A;  1ATA A;  1APO A;  1DVA L;  2XBX L;  2Y5F L;  4LOR A;  4BTT A;  1YGC L;  4Z6A L;  4XLW A;  4LMF A;  2VRS A;  4ZXY L;  1IQK L;  2VWM K;  3FFG L;  3F6U L;  4FM5 A;  1CQE A;  1CX2 A;  1N1I A;  4BDX A;  2PUQ L;  3QMO A;  4JYV L;  1AUT L;  4Y71 B;  2WG4 B;  4XBM A;  1HRF A;  1ADX A;  1KLO A;  2WG3 C;  3HPT A;  2J38 B;  1JL9 A;  2WPK E;  4RUT A;  1NT0 A;  1DX5 I;  2KL7 A;  2Y82 B;  3LC5 B;  4O02 B;  6COX A;  4Y76 B;  1Z6E L;  5L30 L;  2PHB B;  1IOE L;  1COU A;  2BMG A;  1NFY B;  2W2N E;  1NFX B;  1WHE A;  4C16 A;  5K0H B;  3ZYG A;  2Y38 A;  3P5B L;  2UWP B;  1LQD A;  3QH0 A;  5KIR A;  2HOX A;  3KRK A;  1G1T A;  1EAI C;  1WHF A;  4JZF L;  2H9E L;  1IQH L;  3CS7 L;  4COX A;  4CUD A;  3OLT A;  5JBA E;  1P0S L;  4RRX A;  2WFT A;  1ATB A;  2UWL B;  4M11 A;  2P95 L;  5EGM B;  1DQB A;  2I9A A;  4PH9 A;  2Y7Z B;  2BT8 A;  1PGE A;  3ZYI B;  1NQL B;  4X8U L;  1J9C L;  1IP0 A;  3GIS X;  2FLB L;  1FAK L;  1IQN L;  2K2S B;  2VVV L;  1K36 A;  2WFX B;  2RHP A;  1KLI L;  1EPJ A;  3MDL A;  4BTI A;  2WPM E;  4BDW A;  4JZE L;  2XC0 L;  3TK6 B;  3RR3 A;  1L5G B;  1FF7 A;  1YUK B;  1SZB A;  3IJE B;  3LAQ A;  3M37 L;  5E8D A;  3F1S B;  1IQF L;  1HT8 A;  1IVO C;  4CUF A;  5JVY A;  3KQB L;  1HCG B;  2XC4 L;  1PTH A;  3R05 A;  1CVW L;  1L3Y A;  1JBU L;  2VWN L;  2VWO L;  4RRZ A;  2YGO A;  1XKA L;  1I0U A;  2BT7 A;  3TK5 B;  2BOU A;  2FLR L;  1YO8 A;  1A3P A;  3GCX E;  2FD6 A;  2BQW A;  1LMJ A;  1GK5 A;  1MOX C;  2VH6 B;  3LN1 A;  2W3I B;  1QFK L;  1APQ A;  3ELA L;  3FBY A;  3U73 A;  2CJI B;  2MHP A;  1HZ8 A;  1RFN B;  1F0R B;  1TLE A;  1M1X B;  1QIU A;  1IGX A;  4RS0 A;  2H9E C;  4E1G A;  4GU4 A;  2HOR A;  2WPJ E;  2EI7 B;  4NGA L;  5CKN A;  1FAX L;  1DIY A;  1DDX A;  1EMN A;  1G1R A;  1IQL L;  3N8V A;  3HO3 A;  3SOB B;  3KQD L;  1V3X B;  3IIT B;  1IOX A;  2P3T A;  2OYU P;  3HS5 A;  1EMO A;  1IQJ L;  1KSN B;  2WZP P;  4MMY B;  1G2L B;  1IQI L;  4A7I A;  1FFM A;  2XBW L;  1XDT R;  2BOX A;  1CEJ A;  4M10 A;  1BF9 A;  3C9A C;  4ZXX L;  1IQG L;  2Y7X B;  3KK6 A;  1PRH A;  2J34 B;  1IQM L;  1B9W A;  4D0E A;  2PR3 B;  2XBV L;  2TGF A;  1XKB A;  2BOK L;  1EGF A;  2FZZ L;  2YGQ A;  4D0F A;  2G00 L;  2GD4 A;  1EQH A;  1MQ5 L;  1ZAQ A;  3PGH A;  5IKT A;  2DDU A;  1G1Q A;  3CFW A;  1HAE A;  4CUE A;  4Y79 B;  3ZYJ B;  2Y5G L;  2XC5 L;  1C5M F;  1FJS L;  2Q1J B;  1O5D L;  2JJL A;  3N8Y A;  4AQT A;  2J94 B;  5FDQ A;  3N8X A;  2Y80 B;  4YT6 L;  2BZ6 L;  4X8V L;  4NA9 L;  1X7A L;  3TZI A;  1F7E A;  3ENS A;  4Z0K B;  2RA0 L;  1NFU B;  4JYU L;  2P3F N;  5CKM A;  3HS6 A;  1KLJ L;  4Y7A B;  2NPR A;  1EPI A;  3K9X A;  2JKH L;  1LPK A;  3OLU A;  1PXX A;  2J2U B;  1NZI A;  1OB1 C;  1IQE L;  1P9J A;  1JV2 B;  1MQ6 L;  1K37 A;  2BQ7 A;  4YZU B;  1F0S B;  3V65 B;  2P16 L;  1CCV A;  5IKQ A;  2W2P E;  3POY A;  2VH0 B;  3U7U G;  2VJ3 A;  1HX2 A;  3LN0 A;  1LMM A;  4BTU A;  1URK A;  5COX A;  1YUF A;  1PFX L;  3NT1 A;  3TBD A;  4ZHA B;  3KQE L;  3LIW B;  1FSB A;  2P93 L;  3QCW A;  1Q4G A;  2P26 A;  1KIG L;  3BPS E;  2W3K B;  3SOV A;  3NJP C;  2BSF A;  4OTY A;  2KV4 A;  5JB8 E;  3KCG L;  1HAF A;  2RNL A;  5JB9 E;  1V1H A;  2WPH E;  2WPL E;  2ADX A;  3MQE A;  1F7M A;  1FE2 A;  3LC3 B;  4MMX B;  5I46 L;  4Y7B B;  1EBV A;  5F19 A;  4OTJ A;  2MGP A;  2BOH A;  2P94 L;  5IKR A;  2EI6 B;  2VVU L;  4ZH8 B;  3DEM A;  3KL6 B;  1UZJ A;  2P3F L;  3TGF A;  2Y81 B;  1Z6C A;  1HJ7 A;  1UZQ A;  4MMZ B;  1U67 A;  1XFE A;  2XBY L;  3TH3 L;  3CEN L;  5F1A A;  3ASI A;  4RRY A;  2I9B A;  4D90 A;  2BQ6 A;  3BT2 A;  4XL1 A;  5JVZ A;  4ISI L;  2F9B L;  3LTG D;  2WYJ B;  3HO4 A;  2KNI A;  2P3U A;  3S6X A;  2WPI E;  3Q3K B; 
#chains in the Genus database with same CATH homology
 3HS7 A;  3M36 L;  3FCS B;  4O1Z A;  1IGZ A;  2EI8 B;  1W8B L;  2VWL L;  1EZQ B;  2W86 A;  1W7X L;  5JBC E;  5CKQ A;  3LTF B;  4BXS A;  4BXW A;  4JZD L;  2KB9 A;  1NFW B;  2M74 A;  1YUG A;  3N8W A;  3HO5 A;  3Q7D A;  2VVC K;  2W2Q E;  3NTG A;  4X8T L;  1G1S A;  5CIS A;  1ATD A;  2B7D L;  2YGP A;  4ZAE B;  2MGR A;  1G2M B;  3H5C B;  3GCW E;  3EGF A;  1TOZ A;  4ISH L;  4YT7 L;  4TGF A;  2FLG A;  1CVU A;  5IKV A;  1IJQ A;  1ATE A;  1LPG A;  1UZP A;  3SOQ A;  2D1J B;  5L2Y L;  2AYL A;  2W26 B;  1EPH A;  2W2O E;  1HT5 A;  4Y6D B;  2UWO B;  2Y5H L;  1WU1 B;  5KN5 C;  4NG9 L;  2WYG B;  4CSY A;  1UZK A;  4Z0L A;  5L2Z L;  3N8W B;  1N7D A;  1LPZ A;  4A94 C;  2OYE P;  1EPG A;  3N8Y B;  3NTB A;  3N8Z A;  3CA7 A;  4G1M B;  4RRW A;  2BO2 A;  3SW2 A;  2W2M E;  1EQG A;  2J95 B;  3V64 C;  5JBB E;  2J4I B;  1U8C B;  2K2T A;  3BT1 A;  5JW1 A;  2P28 B;  1NPE B;  4X8S L;  3KQC L;  1HRE A;  1TPG A;  1CCF A;  1ATA A;  1APO A;  1DVA L;  2XBX L;  2Y5F L;  4LOR A;  4BTT A;  1YGC L;  4Z6A L;  4XLW A;  4LMF A;  4ZXY L;  1IQK L;  2VWM K;  3FFG L;  3F6U L;  4FM5 A;  1CQE A;  1CX2 A;  1N1I A;  4BDX A;  2PUQ L;  3QMO A;  4JYV L;  1AUT L;  4Y71 B;  2WG4 B;  4XBM A;  1HRF A;  1ADX A;  1KLO A;  2WG3 C;  3HPT A;  2J38 B;  1JL9 A;  2WPK E;  4RUT A;  1NT0 A;  1DX5 I;  2KL7 A;  2Y82 B;  3LC5 B;  4O02 B;  6COX A;  4Y76 B;  1Z6E L;  5L30 L;  2PHB B;  1IOE L;  1COU A;  2BMG A;  1NFY B;  2W2N E;  1NFX B;  1WHE A;  4C16 A;  5K0H B;  3ZYG A;  2Y38 A;  3P5B L;  2UWP B;  1LQD A;  3QH0 A;  5KIR A;  3KRK A;  1G1T A;  1EAI C;  1WHF A;  4JZF L;  2H9E L;  1IQH L;  3CS7 L;  4COX A;  4CUD A;  3OLT A;  5JBA E;  1P0S L;  4RRX A;  2WFT A;  1ATB A;  2UWL B;  4M11 A;  2P95 L;  5EGM B;  1DQB A;  2I9A A;  4PH9 A;  2Y7Z B;  1PGE A;  3ZYI B;  1NQL B;  4X8U L;  1J9C L;  1IP0 A;  3GIS X;  2FLB L;  1FAK L;  1IQN L;  2K2S B;  2VVV L;  1K36 A;  2WFX B;  2RHP A;  1KLI L;  1EPJ A;  3MDL A;  4BTI A;  2WPM E;  4BDW A;  4JZE L;  2XC0 L;  3TK6 B;  3RR3 A;  1L5G B;  1FF7 A;  1YUK B;  1SZB A;  3IJE B;  3LAQ A;  3M37 L;  5E8D A;  3F1S B;  1IQF L;  1HT8 A;  1IVO C;  4CUF A;  5JVY A;  3KQB L;  1HCG B;  2XC4 L;  1PTH A;  3R05 A;  1CVW L;  1L3Y A;  1JBU L;  2VWN L;  2VWO L;  4RRZ A;  2YGO A;  1XKA L;  1I0U A;  3TK5 B;  2BOU A;  2FLR L;  1YO8 A;  1A3P A;  3GCX E;  2FD6 A;  2BQW A;  1LMJ A;  1GK5 A;  1MOX C;  2VH6 B;  3LN1 A;  2W3I B;  1QFK L;  1APQ A;  3ELA L;  3FBY A;  3U73 A;  2CJI B;  2MHP A;  1HZ8 A;  1RFN B;  1F0R B;  1TLE A;  1M1X B;  1IGX A;  4RS0 A;  2H9E C;  4E1G A;  2WPJ E;  2EI7 B;  4NGA L;  5CKN A;  1FAX L;  1DIY A;  1DDX A;  1EMN A;  1G1R A;  1IQL L;  3N8V A;  3HO3 A;  3SOB B;  3KQD L;  1V3X B;  3IIT B;  1IOX A;  2P3T A;  2OYU P;  3HS5 A;  1EMO A;  1IQJ L;  1KSN B;  2WZP P;  4MMY B;  1G2L B;  1IQI L;  4A7I A;  1FFM A;  2XBW L;  1XDT R;  2BOX A;  1CEJ A;  4M10 A;  1BF9 A;  3C9A C;  4ZXX L;  1IQG L;  2Y7X B;  3KK6 A;  1PRH A;  2J34 B;  1IQM L;  1B9W A;  4D0E A;  2PR3 B;  2XBV L;  2TGF A;  1XKB A;  2BOK L;  1EGF A;  2FZZ L;  2YGQ A;  4D0F A;  2G00 L;  2GD4 A;  1EQH A;  1MQ5 L;  1ZAQ A;  3PGH A;  5IKT A;  2DDU A;  1G1Q A;  3CFW A;  1HAE A;  4CUE A;  4Y79 B;  3ZYJ B;  2Y5G L;  2XC5 L;  1C5M F;  1FJS L;  2Q1J B;  1O5D L;  3N8Y A;  4AQT A;  2J94 B;  5FDQ A;  3N8X A;  2Y80 B;  4YT6 L;  2BZ6 L;  4X8V L;  4NA9 L;  1X7A L;  3TZI A;  1F7E A;  3ENS A;  4Z0K B;  2RA0 L;  1NFU B;  4JYU L;  2P3F N;  5CKM A;  3HS6 A;  1KLJ L;  4Y7A B;  2NPR A;  1EPI A;  3K9X A;  2JKH L;  1LPK A;  3OLU A;  1PXX A;  2J2U B;  1NZI A;  1OB1 C;  1IQE L;  1P9J A;  1JV2 B;  1MQ6 L;  1K37 A;  2BQ7 A;  4YZU B;  1F0S B;  3V65 B;  2P16 L;  1CCV A;  5IKQ A;  2W2P E;  3POY A;  2VH0 B;  3U7U G;  2VJ3 A;  1HX2 A;  3LN0 A;  1LMM A;  4BTU A;  1URK A;  5COX A;  1YUF A;  1PFX L;  3NT1 A;  3TBD A;  4ZHA B;  3KQE L;  3LIW B;  1FSB A;  2P93 L;  3QCW A;  1Q4G A;  2P26 A;  1KIG L;  3BPS E;  2W3K B;  3SOV A;  3NJP C;  4OTY A;  2KV4 A;  5JB8 E;  3KCG L;  1HAF A;  2RNL A;  5JB9 E;  2WPH E;  2WPL E;  2ADX A;  3MQE A;  1F7M A;  1FE2 A;  3LC3 B;  4MMX B;  5I46 L;  4Y7B B;  1EBV A;  5F19 A;  4OTJ A;  2MGP A;  2BOH A;  2P94 L;  5IKR A;  2EI6 B;  2VVU L;  4ZH8 B;  3DEM A;  3KL6 B;  1UZJ A;  2P3F L;  3TGF A;  2Y81 B;  1Z6C A;  1HJ7 A;  1UZQ A;  4MMZ B;  1U67 A;  1XFE A;  2XBY L;  3TH3 L;  3CEN L;  5F1A A;  3ASI A;  4RRY A;  2I9B A;  4D90 A;  2BQ6 A;  3BT2 A;  4XL1 A;  5JVZ A;  4ISI L;  2F9B L;  3LTG D;  2WYJ B;  3HO4 A;  2KNI A;  2P3U A;  3S6X A;  2WPI E;  3Q3K B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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