2W2ME

Wt pcsk9-deltac bound to wt egf-a of ldlr
Total Genus 7
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
49
structure length
49
Chain Sequence
NLYFQGAMGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/receptor
source organism Homo sapiens
publication title Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants.
pubmed doi rcsb
molecule keywords PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
total genus 7
structure length 49
sequence length 49
ec nomenclature
pdb deposition date 2008-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF12662 cEGF Complement Clr-like EGF-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2w2mE00
3ZYGA 1TPGA 1QFKL 2Y82B 2VVUL 3KRKA 2XC5L 1C5MF 3N8YA 3PGHA 5KN5C 2WG4B 1UZPA 4ISIL 4O1ZA 2KV4A 3N8ZA 3ELAL 1KSNB 1URKA 2BMGA 1XFEA 5CKNA 2WYJB 1HREA 1IVOC 5IKTA 3HO3A 1U8CB 1LPGA 3SOVA 3KQEL 1P0SL 1SZBA 1J9CL 2BQ7A 5IKRA 2FLGA 1PTHA 4X8SL 4M11A 3BT1A 1ATDA 1FF7A 1KLJL 2W2OE 3N8WA 2WFTA 5JVYA 3TGFA 2XBWL 3KL6B 2W2NE 1NT0A 4NG9L 3N8YB 1YUKB 4BXSA 3QMOA 6COXA 4X8TL 3M37L 2FLBL 5I46L 1IOXA 2Y80B 5F1AA 2W2ME 1G1SA 1LPZA 3KQBL 1HX2A 1IQEL 4NA9L 1K37A 4XBMA 2PHBB 1OB1C 1EMOA 1IOEL 3ASIA 3CENL 1IQGL 1NFWB 2VWMK 4MMZB 5E8DA 5L2ZL 2Y5GL 2W86A 3GCXE 2P3UA 3HS6A 3CA7A 3HO5A 4AQTA 2I9AA 2VWNL 1F0SB 1DDXA 4ZXYL 2WPLE 1HZ8A 5F19A 1BF9A 2RA0L 1MOXC 1YGCL 2KB9A 4Y6DB 3LN1A 1GK5A 3TH3L 3N8XA 4O02B 2WFXB 1APQA 3IJEB 1U67A 1EQGA 1CCFA 2K2TA 1KLIL 4FM5A 4TGFA 5JBAE 2WPHE 3FFGL 2WPIE 5IKQA 2Y38A 3DEMA 1IQNL 1KLOA 3KQDL 5JVZA 4LMFA 1CCVA 1LMJA 1WHFA 1A3PA 3LTFB 1PRHA 4RRWA 4Z0KB 5JW1A 5EGMB 1ZAQA 2BO2A 5COXA 3F6UL 4JYUL 4ZHAB 4RRYA 5L30L 4BXWA 1P9JA 1XKBA 4LORA 5L2YL 1NZIA 3BT2A 1IJQA 4YT6L 4E1GA 1G1RA 1M1XB 1N7DA 1YO8A 3BPSE 1COUA 1EGFA 3SW2A 1NPEB 1AUTL 4OTJA 3P5BL 3CS7L 2PUQL 4JYVL 4CUDA 5K0HB 4Y76B 2W3KB 2WPKE 1IQFL 1EAIC 2J34B 2VWOL 2CJIB 3TBDA 3KK6A 4RUTA 2GD4A 1G2LB 2H9EL 3M36L 1Z6CA 4A7IA 1G1TA 1PXXA 1DX5I 1V3XB 2P28B 2NPRA 4CSYA 2RNLA 2Y5FL 1W8BL 3IITB 2P95L 4JZDL 4M10A 3TK6B 1I0UA 1EPGA 4MMXB 2UWOB 3GCWE 3ENSA 1HJ7A 3OLUA 1EZQB 3K9XA 4Y7AB 2P93L 4D0FA 1WU1B 2XC0L 2FD6A 1HT5A 1IQLL 2TGFA 3KCGL 2G00L 4YZUB 2BOKL 2VVCK 4BTIA 2OYUP 2W26B 3Q7DA 3SOBB 3EGFA 3N8WB 1CVUA 3MQEA 3QH0A 1FAKL 1DVAL 2VWLL 3R05A 1NFXB 4JZFL 1FSBA 4X8UL 5CKMA 2BOHA 4CUFA 1PFXL 3NT1A 3POYA 2UWLB 1F7EA 3U73A 2J95B 3TK5B 4MMYB 3ZYIB 1TOZA 1JBUL 1IGXA 4OTYA 3LN0A 3LC5B 1F0RB 2BQWA 2VH6B 2Y5HL 3TZIA 4CUEA 4BTTA 2Y7XB 5CISA 1X7AL 2BQ6A 4RS0A 1ATAA 3NJPC 3HO4A 3MDLA 1CX2A 3V65B 3HPTA 2P16L 1IQKL 1PGEA 2P26A 2WPJE 4Y71B 1IQML 3Q3KB 1G2MB 1L3YA 3V64C 1ATBA 3RR3A 4COXA 2XBYL 3NTBA 1IQIL 3NTGA 4ISHL 4Y7BB 2MGPA 1DQBA 2P94L 1K36A 3SOQA 1HAFA 1G1QA 2PR3B 2UWPB 3U7UG 2EI6B 4RRZA 1EBVA 1FAXL 4D0EA 3FCSB 4Z0LA 1HAEA 2P3FL 1F7MA 2YGPA 2W3IB 1EPJA 5JBCE 1HRFA 1APOA 1FE2A 2AYLA 2VJ3A 2P3TA 1MQ6L 1DIYA 1IP0A 1EMNA 5FDQA 1UZKA 4ZH8B 2EI8B 4X8VL 3KQCL 1EPIA 3LTGD 1HCGB 2W2QE 2FZZL 3HS7A 4JZEL 1LPKA 1JL9A 1WHEA 4G1MB 3QCWA 1IQJL 4Y79B 2BZ6L 3LIWB 2ADXA 3C9AC 1HT8A 4PH9A 2J38B 2JKHL 2J94B 1FFMA 1Q4GA 1O5DL 1W7XL 3N8VA 2B7DL 5CKQA 2FLRL 1KIGL 4D90A 4ZXXL 3F1SB 3LAQA 1TLEA 2VH0B 2OYEP 4BDWA 5JB8E 2KL7A 2F9BL 3H5CB 1ATEA 1NQLB 3CFWA 4Z6AL 1IGZA 4YT7L 1FJSL 1NFYB 1RFNB 5KIRA 3HS5A 4C16A 2VVVL 4NGAL 1XKAL 2MHPA 1YUGA 2BOXA 1CVWL 2DDUA 2XC4L 4BDXA 5JB9E 1NFUB 4XL1A 1CEJA 1YUFA 2RHPA 4RRXA 4BTUA 1L5GB 1N1IA 4XLWA 2WG3C 1JV2B 1EQHA 1MQ5L 2J2UB 2WYGB 3OLTA 1CQEA 2EI7B 5JBBE 1UZJA 2Q1JB 2W2PE 3FBYA 1EPHA 2MGRA 2BOUA 1IQHL 3GISX 2Y81B 2D1JB 2YGOA 1ADXA 1XDTR 4ZAEB 2J4IB 2I9BA 2M74A 2WPME 5IKVA 2XBVL 3LC3B 1LQDA 2K2SB 2XBXL 1Z6EL 1B9WA 3ZYJB 1UZQA 2Y7ZB 2P3FN
chains in the Genus database with same CATH superfamily
3ZYGA 1TPGA 1QFKL 2Y82B 2VVUL 3KRKA 2XC5L 1C5MF 3N8YA 3PGHA 5KN5C 2WG4B 1UZPA 4ISIL 4O1ZA 2KV4A 3N8ZA 3ELAL 1KSNB 1URKA 2BMGA 1XFEA 5CKNA 2WYJB 1HREA 1IVOC 5IKTA 3HO3A 1U8CB 1LPGA 3SOVA 3KQEL 1P0SL 1SZBA 1J9CL 2BQ7A 5IKRA 2FLGA 1PTHA 4X8SL 4M11A 3BT1A 1ATDA 1FF7A 1KLJL 2W2OE 4GU3A 3N8WA 2WFTA 5JVYA 3TGFA 2BT8A 2XBWL 3KL6B 2W2NE 1NT0A 4NG9L 3N8YB 1YUKB 4BXSA 3QMOA 6COXA 4X8TL 3M37L 2BT7A 2FLBL 5I46L 1IOXA 2Y80B 5F1AA 2W2ME 1G1SA 1LPZA 3KQBL 1HX2A 1IQEL 4NA9L 1K37A 4XBMA 2PHBB 1OB1C 1EMOA 1IOEL 3ASIA 3CENL 1IQGL 1NFWB 2VWMK 4MMZB 1LMMA 5E8DA 5L2ZL 2Y5GL 2W86A 3GCXE 2P3UA 3HS6A 3CA7A 2HOXA 3HO5A 4AQTA 1KKEA 2I9AA 2VWNL 1F0SB 1DDXA 4ZXYL 2WPLE 1HZ8A 5F19A 1BF9A 2RA0L 1MOXC 1YGCL 2KB9A 4Y6DB 3LN1A 1GK5A 3TH3L 3N8XA 4O02B 2WFXB 1APQA 3IJEB 1U67A 1EQGA 1CCFA 2K2TA 1KLIL 4FM5A 4TGFA 5JBAE 2WPHE 3FFGL 2WPIE 5IKQA 2Y38A 3DEMA 1IQNL 1KLOA 3KQDL 5JVZA 4LMFA 1CCVA 1LMJA 1WHFA 1A3PA 3LTFB 1PRHA 4RRWA 4Z0KB 5JW1A 5EGMB 1ZAQA 2BO2A 5COXA 3F6UL 4JYUL 4GU4A 4ZHAB 4RRYA 5L30L 4BXWA 1P9JA 1XKBA 4LORA 5L2YL 1NZIA 3BT2A 1IJQA 4YT6L 4E1GA 1G1RA 1M1XB 1N7DA 1YO8A 3BPSE 1COUA 1EGFA 3SW2A 1NPEB 1AUTL 4OTJA 3P5BL 3CS7L 2PUQL 4JYVL 4CUDA 5K0HB 4Y76B 2W3KB 2WPKE 1IQFL 1EAIC 2J34B 2KNIA 2CJIB 2VWOL 3TBDA 3KK6A 4RUTA 2GD4A 1G2LB 2H9EL 3M36L 1Z6CA 4A7IA 1G1TA 1PXXA 1DX5I 1V3XB 2P28B 2NPRA 4CSYA 2RNLA 2Y5FL 1W8BL 3IITB 2P95L 4JZDL 4M10A 3TK6B 1I0UA 1EPGA 4MMXB 2UWOB 3GCWE 3ENSA 1HJ7A 3OLUA 1EZQB 3K9XA 4Y7AB 2P93L 4D0FA 4A94C 1WU1B 2XC0L 2FD6A 1HT5A 1IQLL 2TGFA 3KCGL 2G00L 4YZUB 2BOKL 2VVCK 4BTIA 2OYUP 2W26B 3Q7DA 3SOBB 3EGFA 3N8WB 1CVUA 3MQEA 3QH0A 1FAKL 1DVAL 2VWLL 3R05A 1NFXB 4JZFL 1FSBA 4X8UL 2JJLA 1V1HA 5CKMA 2BOHA 4CUFA 1PFXL 3NT1A 2VRSA 3POYA 3S6XA 2UWLB 1LK9A 3U73A 1F7EA 2J95B 3TK5B 4MMYB 2BSFA 3ZYIB 1TOZA 1JBUL 1IGXA 2HORA 4OTYA 3LN0A 3LC5B 1F0RB 2BQWA 2VH6B 2Y5HL 3TZIA 4CUEA 4BTTA 2Y7XB 5CISA 1X7AL 2BQ6A 4RS0A 1ATAA 3NJPC 1V1IA 3HO4A 3MDLA 1CX2A 3V65B 3HPTA 2P16L 1IQKL 1PGEA 2P26A 2WPJE 4Y71B 1IQML 3Q3KB 1G2MB 1L3YA 3V64C 1ATBA 3RR3A 4COXA 2XBYL 3NTBA 2YGQA 1IQIL 2H9EC 3NTGA 4ISHL 4Y7BB 2MGPA 1DQBA 2P94L 1K36A 3SOQA 1HAFA 1G1QA 2PR3B 2UWPB 3U7UG 2EI6B 4RRZA 1EBVA 1FAXL 4D0EA 3FCSB 4Z0LA 1HAEA 2P3FL 1F7MA 2YGPA 2W3IB 1EPJA 5JBCE 2WZPP 1APOA 1HRFA 1FE2A 2AYLA 2VJ3A 2P3TA 1MQ6L 1DIYA 1IP0A 1EMNA 5FDQA 1UZKA 4ZH8B 2EI8B 4X8VL 3KQCL 1EPIA 3LTGD 1HCGB 2W2QE 2FZZL 3HS7A 4JZEL 1LPKA 1JL9A 1WHEA 4G1MB 3QCWA 1IQJL 4Y79B 2BZ6L 3LIWB 2ADXA 3C9AC 1HT8A 4PH9A 2J38B 2JKHL 2J94B 1FFMA 1Q4GA 1O5DL 1W7XL 3N8VA 2B7DL 5CKQA 2FLRL 1KIGL 4D90A 4ZXXL 3F1SB 3LAQA 1TLEA 2VH0B 2OYEP 4BDWA 5JB8E 2KL7A 2F9BL 3H5CB 1ATEA 1NQLB 3CFWA 4Z6AL 1IGZA 4YT7L 1FJSL 1NFYB 1RFNB 5KIRA 3HS5A 4C16A 2VVVL 4NGAL 1XKAL 2MHPA 1YUGA 2BOXA 1CVWL 2DDUA 2XC4L 4BDXA 5JB9E 1NFUB 4XL1A 1CEJA 1YUFA 2RHPA 4RRXA 4BTUA 1L5GB 1N1IA 4XLWA 2WG3C 1JV2B 1EQHA 1MQ5L 2J2UB 2WYGB 3OLTA 1CQEA 2EI7B 5JBBE 1UZJA 2Q1JB 2W2PE 3FBYA 1EPHA 2MGRA 1QIUA 2BOUA 1IQHL 3GISX 2Y81B 2D1JB 2YGOA 1ADXA 1XDTR 4ZAEB 2J4IB 2I9BA 2M74A 2WPME 5IKVA 2XBVL 3LC3B 1LQDA 2K2SB 2XBXL 1Z6EL 1B9WA 3ZYJB 1UZQA 2Y7ZB 2P3FN
chains in the Genus database with same CATH topology
3ZYGA 1TPGA 1QFKL 2Y82B 2VVUL 3KRKA 2XC5L 1C5MF 3N8YA 3PGHA 5KN5C 2WG4B 1UZPA 4ISIL 4O1ZA 2KV4A 3N8ZA 3ELAL 1KSNB 1URKA 2BMGA 1XFEA 5CKNA 2WYJB 1HREA 1IVOC 5IKTA 3HO3A 1U8CB 1LPGA 3SOVA 3KQEL 1P0SL 1SZBA 1J9CL 2BQ7A 5IKRA 2FLGA 1PTHA 4X8SL 4M11A 3BT1A 1ATDA 1FF7A 1KLJL 2W2OE 3N8WA 2WFTA 5JVYA 3TGFA 2XBWL 3KL6B 2W2NE 1NT0A 4NG9L 3N8YB 1YUKB 4BXSA 3QMOA 6COXA 4X8TL 3M37L 2FLBL 5I46L 1IOXA 2Y80B 5F1AA 2W2ME 1G1SA 1LPZA 3KQBL 1HX2A 1IQEL 4NA9L 1K37A 4XBMA 2PHBB 1OB1C 1EMOA 1IOEL 3ASIA 3CENL 1IQGL 1NFWB 2VWMK 4MMZB 1LMMA 5E8DA 5L2ZL 2Y5GL 2W86A 3GCXE 2P3UA 3HS6A 3CA7A 3HO5A 4AQTA 2I9AA 2VWNL 1F0SB 1DDXA 4ZXYL 2WPLE 1HZ8A 5F19A 1BF9A 2RA0L 1MOXC 1YGCL 2KB9A 4Y6DB 3LN1A 1GK5A 3TH3L 3N8XA 4O02B 2WFXB 1APQA 3IJEB 1U67A 1EQGA 1CCFA 2K2TA 1KLIL 4FM5A 4TGFA 5JBAE 2WPHE 3FFGL 2WPIE 5IKQA 2Y38A 3DEMA 1IQNL 1KLOA 3KQDL 5JVZA 4LMFA 1CCVA 1LMJA 1WHFA 1A3PA 3LTFB 1PRHA 4RRWA 4Z0KB 5JW1A 5EGMB 1ZAQA 2BO2A 5COXA 3F6UL 4JYUL 4ZHAB 4RRYA 5L30L 4BXWA 1P9JA 1XKBA 4LORA 5L2YL 1NZIA 3BT2A 1IJQA 4YT6L 4E1GA 1G1RA 1M1XB 1N7DA 1YO8A 3BPSE 1COUA 1EGFA 3SW2A 1NPEB 1AUTL 4OTJA 3P5BL 3CS7L 2PUQL 4JYVL 4CUDA 5K0HB 4Y76B 2W3KB 2WPKE 1IQFL 1EAIC 2J34B 2KNIA 2CJIB 2VWOL 3TBDA 3KK6A 4RUTA 2GD4A 1G2LB 2H9EL 3M36L 1Z6CA 4A7IA 1G1TA 1PXXA 1DX5I 1V3XB 2P28B 2NPRA 4CSYA 2RNLA 2Y5FL 1W8BL 3IITB 2P95L 4JZDL 4M10A 3TK6B 1I0UA 1EPGA 4MMXB 2UWOB 3GCWE 3ENSA 1HJ7A 3OLUA 1EZQB 3K9XA 4Y7AB 2P93L 4D0FA 4A94C 1WU1B 2XC0L 2FD6A 1HT5A 1IQLL 2TGFA 3KCGL 2G00L 4YZUB 2BOKL 2VVCK 4BTIA 2OYUP 2W26B 3Q7DA 3SOBB 3EGFA 3N8WB 1CVUA 3MQEA 3QH0A 1FAKL 1DVAL 2VWLL 3R05A 1NFXB 4JZFL 1FSBA 4X8UL 5CKMA 2BOHA 4CUFA 1PFXL 3NT1A 3POYA 3S6XA 2UWLB 1F7EA 3U73A 2J95B 3TK5B 4MMYB 3ZYIB 1TOZA 1JBUL 1IGXA 4OTYA 3LN0A 3LC5B 1F0RB 2BQWA 2VH6B 2Y5HL 3TZIA 4CUEA 4BTTA 2Y7XB 5CISA 1X7AL 2BQ6A 4RS0A 1ATAA 3NJPC 3HO4A 3MDLA 1CX2A 3V65B 3HPTA 2P16L 1IQKL 1PGEA 2P26A 2WPJE 4Y71B 1IQML 3Q3KB 1G2MB 1L3YA 3V64C 1ATBA 3RR3A 4COXA 2XBYL 3NTBA 2YGQA 1IQIL 2H9EC 3NTGA 4ISHL 4Y7BB 2MGPA 1DQBA 2P94L 1K36A 3SOQA 1HAFA 1G1QA 2PR3B 2UWPB 3U7UG 2EI6B 4RRZA 1EBVA 1FAXL 4D0EA 3FCSB 4Z0LA 1HAEA 2P3FL 1F7MA 2YGPA 2W3IB 1EPJA 5JBCE 2WZPP 1APOA 1HRFA 1FE2A 2AYLA 2VJ3A 2P3TA 1MQ6L 1DIYA 1IP0A 1EMNA 5FDQA 1UZKA 4ZH8B 2EI8B 4X8VL 3KQCL 1EPIA 3LTGD 1HCGB 2W2QE 2FZZL 3HS7A 4JZEL 1LPKA 1JL9A 1WHEA 4G1MB 3QCWA 1IQJL 4Y79B 2BZ6L 3LIWB 2ADXA 3C9AC 1HT8A 4PH9A 2J38B 2JKHL 2J94B 1FFMA 1Q4GA 1O5DL 1W7XL 3N8VA 2B7DL 5CKQA 2FLRL 1KIGL 4D90A 4ZXXL 3F1SB 3LAQA 1TLEA 2VH0B 2OYEP 4BDWA 5JB8E 2KL7A 2F9BL 3H5CB 1ATEA 1NQLB 3CFWA 4Z6AL 1IGZA 4YT7L 1FJSL 1NFYB 1RFNB 5KIRA 3HS5A 4C16A 2VVVL 4NGAL 1XKAL 2MHPA 1YUGA 2BOXA 1CVWL 2DDUA 2XC4L 4BDXA 5JB9E 1NFUB 4XL1A 1CEJA 1YUFA 2RHPA 4RRXA 4BTUA 1L5GB 1N1IA 4XLWA 2WG3C 1JV2B 1EQHA 1MQ5L 2J2UB 2WYGB 3OLTA 1CQEA 2EI7B 5JBBE 1UZJA 2Q1JB 2W2PE 3FBYA 1EPHA 2MGRA 2BOUA 1IQHL 3GISX 2Y81B 2D1JB 2YGOA 1ADXA 1XDTR 4ZAEB 2J4IB 2I9BA 2M74A 2WPME 5IKVA 2XBVL 3LC3B 1LQDA 2K2SB 2XBXL 1Z6EL 1B9WA 3ZYJB 1UZQA 2Y7ZB 2P3FN
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZYG A;  1TPG A;  1QFK L;  2Y82 B;  2VVU L;  3KRK A;  2XC5 L;  1C5M F;  3N8Y A;  3PGH A;  5KN5 C;  2WG4 B;  1UZP A;  4ISI L;  4O1Z A;  2KV4 A;  3N8Z A;  3ELA L;  1KSN B;  1URK A;  2BMG A;  1XFE A;  5CKN A;  2WYJ B;  1HRE A;  1IVO C;  5IKT A;  3HO3 A;  1U8C B;  1LPG A;  3SOV A;  3KQE L;  1P0S L;  1SZB A;  1J9C L;  2BQ7 A;  5IKR A;  2FLG A;  1PTH A;  4X8S L;  4M11 A;  3BT1 A;  1ATD A;  1FF7 A;  1KLJ L;  2W2O E;  3N8W A;  2WFT A;  5JVY A;  3TGF A;  2XBW L;  3KL6 B;  2W2N E;  1NT0 A;  4NG9 L;  3N8Y B;  1YUK B;  4BXS A;  3QMO A;  6COX A;  4X8T L;  3M37 L;  2FLB L;  5I46 L;  1IOX A;  2Y80 B;  5F1A A;  2W2M E;  1G1S A;  1LPZ A;  3KQB L;  1HX2 A;  1IQE L;  4NA9 L;  1K37 A;  4XBM A;  2PHB B;  1OB1 C;  1EMO A;  1IOE L;  3ASI A;  3CEN L;  1IQG L;  1NFW B;  2VWM K;  4MMZ B;  5E8D A;  5L2Z L;  2Y5G L;  2W86 A;  3GCX E;  2P3U A;  3HS6 A;  3CA7 A;  3HO5 A;  4AQT A;  2I9A A;  2VWN L;  1F0S B;  1DDX A;  4ZXY L;  2WPL E;  1HZ8 A;  5F19 A;  1BF9 A;  2RA0 L;  1MOX C;  1YGC L;  2KB9 A;  4Y6D B;  3LN1 A;  1GK5 A;  3TH3 L;  3N8X A;  4O02 B;  2WFX B;  1APQ A;  3IJE B;  1U67 A;  1EQG A;  1CCF A;  2K2T A;  1KLI L;  4FM5 A;  4TGF A;  5JBA E;  2WPH E;  3FFG L;  2WPI E;  5IKQ A;  2Y38 A;  3DEM A;  1IQN L;  1KLO A;  3KQD L;  5JVZ A;  4LMF A;  1CCV A;  1LMJ A;  1WHF A;  1A3P A;  3LTF B;  1PRH A;  4RRW A;  4Z0K B;  5JW1 A;  5EGM B;  1ZAQ A;  2BO2 A;  5COX A;  3F6U L;  4JYU L;  4ZHA B;  4RRY A;  5L30 L;  4BXW A;  1P9J A;  1XKB A;  4LOR A;  5L2Y L;  1NZI A;  3BT2 A;  1IJQ A;  4YT6 L;  4E1G A;  1G1R A;  1M1X B;  1N7D A;  1YO8 A;  3BPS E;  1COU A;  1EGF A;  3SW2 A;  1NPE B;  1AUT L;  4OTJ A;  3P5B L;  3CS7 L;  2PUQ L;  4JYV L;  4CUD A;  5K0H B;  4Y76 B;  2W3K B;  2WPK E;  1IQF L;  1EAI C;  2J34 B;  2VWO L;  2CJI B;  3TBD A;  3KK6 A;  4RUT A;  2GD4 A;  1G2L B;  2H9E L;  3M36 L;  1Z6C A;  4A7I A;  1G1T A;  1PXX A;  1DX5 I;  1V3X B;  2P28 B;  2NPR A;  4CSY A;  2RNL A;  2Y5F L;  1W8B L;  3IIT B;  2P95 L;  4JZD L;  4M10 A;  3TK6 B;  1I0U A;  1EPG A;  4MMX B;  2UWO B;  3GCW E;  3ENS A;  1HJ7 A;  3OLU A;  1EZQ B;  3K9X A;  4Y7A B;  2P93 L;  4D0F A;  1WU1 B;  2XC0 L;  2FD6 A;  1HT5 A;  1IQL L;  2TGF A;  3KCG L;  2G00 L;  4YZU B;  2BOK L;  2VVC K;  4BTI A;  2OYU P;  2W26 B;  3Q7D A;  3SOB B;  3EGF A;  3N8W B;  1CVU A;  3MQE A;  3QH0 A;  1FAK L;  1DVA L;  2VWL L;  3R05 A;  1NFX B;  4JZF L;  1FSB A;  4X8U L;  5CKM A;  2BOH A;  4CUF A;  1PFX L;  3NT1 A;  3POY A;  2UWL B;  1F7E A;  3U73 A;  2J95 B;  3TK5 B;  4MMY B;  3ZYI B;  1TOZ A;  1JBU L;  1IGX A;  4OTY A;  3LN0 A;  3LC5 B;  1F0R B;  2BQW A;  2VH6 B;  2Y5H L;  3TZI A;  4CUE A;  4BTT A;  2Y7X B;  5CIS A;  1X7A L;  2BQ6 A;  4RS0 A;  1ATA A;  3NJP C;  3HO4 A;  3MDL A;  1CX2 A;  3V65 B;  3HPT A;  2P16 L;  1IQK L;  1PGE A;  2P26 A;  2WPJ E;  4Y71 B;  1IQM L;  3Q3K B;  1G2M B;  1L3Y A;  3V64 C;  1ATB A;  3RR3 A;  4COX A;  2XBY L;  3NTB A;  1IQI L;  3NTG A;  4ISH L;  4Y7B B;  2MGP A;  1DQB A;  2P94 L;  1K36 A;  3SOQ A;  1HAF A;  1G1Q A;  2PR3 B;  2UWP B;  3U7U G;  2EI6 B;  4RRZ A;  1EBV A;  1FAX L;  4D0E A;  3FCS B;  4Z0L A;  1HAE A;  2P3F L;  1F7M A;  2YGP A;  2W3I B;  1EPJ A;  5JBC E;  1HRF A;  1APO A;  1FE2 A;  2AYL A;  2VJ3 A;  2P3T A;  1MQ6 L;  1DIY A;  1IP0 A;  1EMN A;  5FDQ A;  1UZK A;  4ZH8 B;  2EI8 B;  4X8V L;  3KQC L;  1EPI A;  3LTG D;  1HCG B;  2W2Q E;  2FZZ L;  3HS7 A;  4JZE L;  1LPK A;  1JL9 A;  1WHE A;  4G1M B;  3QCW A;  1IQJ L;  4Y79 B;  2BZ6 L;  3LIW B;  2ADX A;  3C9A C;  1HT8 A;  4PH9 A;  2J38 B;  2JKH L;  2J94 B;  1FFM A;  1Q4G A;  1O5D L;  1W7X L;  3N8V A;  2B7D L;  5CKQ A;  2FLR L;  1KIG L;  4D90 A;  4ZXX L;  3F1S B;  3LAQ A;  1TLE A;  2VH0 B;  2OYE P;  4BDW A;  5JB8 E;  2KL7 A;  2F9B L;  3H5C B;  1ATE A;  1NQL B;  3CFW A;  4Z6A L;  1IGZ A;  4YT7 L;  1FJS L;  1NFY B;  1RFN B;  5KIR A;  3HS5 A;  4C16 A;  2VVV L;  4NGA L;  1XKA L;  2MHP A;  1YUG A;  2BOX A;  1CVW L;  2DDU A;  2XC4 L;  4BDX A;  5JB9 E;  1NFU B;  4XL1 A;  1CEJ A;  1YUF A;  2RHP A;  4RRX A;  4BTU A;  1L5G B;  1N1I A;  4XLW A;  2WG3 C;  1JV2 B;  1EQH A;  1MQ5 L;  2J2U B;  2WYG B;  3OLT A;  1CQE A;  2EI7 B;  5JBB E;  1UZJ A;  2Q1J B;  2W2P E;  3FBY A;  1EPH A;  2MGR A;  2BOU A;  1IQH L;  3GIS X;  2Y81 B;  2D1J B;  2YGO A;  1ADX A;  1XDT R;  4ZAE B;  2J4I B;  2I9B A;  2M74 A;  2WPM E;  5IKV A;  2XBV L;  3LC3 B;  1LQD A;  2K2S B;  2XBX L;  1Z6E L;  1B9W A;  3ZYJ B;  1UZQ A;  2Y7Z B;  2P3F N; 
#chains in the Genus database with same CATH topology
 3ZYG A;  1TPG A;  1QFK L;  2Y82 B;  2VVU L;  3KRK A;  2XC5 L;  1C5M F;  3N8Y A;  3PGH A;  5KN5 C;  2WG4 B;  1UZP A;  4ISI L;  4O1Z A;  2KV4 A;  3N8Z A;  3ELA L;  1KSN B;  1URK A;  2BMG A;  1XFE A;  5CKN A;  2WYJ B;  1HRE A;  1IVO C;  5IKT A;  3HO3 A;  1U8C B;  1LPG A;  3SOV A;  3KQE L;  1P0S L;  1SZB A;  1J9C L;  2BQ7 A;  5IKR A;  2FLG A;  1PTH A;  4X8S L;  4M11 A;  3BT1 A;  1ATD A;  1FF7 A;  1KLJ L;  2W2O E;  4GU3 A;  3N8W A;  2WFT A;  5JVY A;  3TGF A;  2BT8 A;  2XBW L;  3KL6 B;  2W2N E;  1NT0 A;  4NG9 L;  3N8Y B;  1YUK B;  4BXS A;  3QMO A;  6COX A;  4X8T L;  3M37 L;  2BT7 A;  2FLB L;  5I46 L;  1IOX A;  2Y80 B;  5F1A A;  2W2M E;  1G1S A;  1LPZ A;  3KQB L;  1HX2 A;  1IQE L;  4NA9 L;  1K37 A;  4XBM A;  2PHB B;  1OB1 C;  1EMO A;  1IOE L;  3ASI A;  3CEN L;  1IQG L;  1NFW B;  2VWM K;  4MMZ B;  1LMM A;  5E8D A;  5L2Z L;  2Y5G L;  2W86 A;  3GCX E;  2P3U A;  3HS6 A;  3CA7 A;  2HOX A;  3HO5 A;  4AQT A;  1KKE A;  2I9A A;  2VWN L;  1F0S B;  1DDX A;  4ZXY L;  2WPL E;  1HZ8 A;  5F19 A;  1BF9 A;  2RA0 L;  1MOX C;  1YGC L;  2KB9 A;  4Y6D B;  3LN1 A;  1GK5 A;  3TH3 L;  3N8X A;  4O02 B;  2WFX B;  1APQ A;  3IJE B;  1U67 A;  1EQG A;  1CCF A;  2K2T A;  1KLI L;  4FM5 A;  4TGF A;  5JBA E;  2WPH E;  3FFG L;  2WPI E;  5IKQ A;  2Y38 A;  3DEM A;  1IQN L;  1KLO A;  3KQD L;  5JVZ A;  4LMF A;  1CCV A;  1LMJ A;  1WHF A;  1A3P A;  3LTF B;  1PRH A;  4RRW A;  4Z0K B;  5JW1 A;  5EGM B;  1ZAQ A;  2BO2 A;  5COX A;  3F6U L;  4JYU L;  4GU4 A;  4ZHA B;  4RRY A;  5L30 L;  4BXW A;  1P9J A;  1XKB A;  4LOR A;  5L2Y L;  1NZI A;  3BT2 A;  1IJQ A;  4YT6 L;  4E1G A;  1G1R A;  1M1X B;  1N7D A;  1YO8 A;  3BPS E;  1COU A;  1EGF A;  3SW2 A;  1NPE B;  1AUT L;  4OTJ A;  3P5B L;  3CS7 L;  2PUQ L;  4JYV L;  4CUD A;  5K0H B;  4Y76 B;  2W3K B;  2WPK E;  1IQF L;  1EAI C;  2J34 B;  2KNI A;  2CJI B;  2VWO L;  3TBD A;  3KK6 A;  4RUT A;  2GD4 A;  1G2L B;  2H9E L;  3M36 L;  1Z6C A;  4A7I A;  1G1T A;  1PXX A;  1DX5 I;  1V3X B;  2P28 B;  2NPR A;  4CSY A;  2RNL A;  2Y5F L;  1W8B L;  3IIT B;  2P95 L;  4JZD L;  4M10 A;  3TK6 B;  1I0U A;  1EPG A;  4MMX B;  2UWO B;  3GCW E;  3ENS A;  1HJ7 A;  3OLU A;  1EZQ B;  3K9X A;  4Y7A B;  2P93 L;  4D0F A;  4A94 C;  1WU1 B;  2XC0 L;  2FD6 A;  1HT5 A;  1IQL L;  2TGF A;  3KCG L;  2G00 L;  4YZU B;  2BOK L;  2VVC K;  4BTI A;  2OYU P;  2W26 B;  3Q7D A;  3SOB B;  3EGF A;  3N8W B;  1CVU A;  3MQE A;  3QH0 A;  1FAK L;  1DVA L;  2VWL L;  3R05 A;  1NFX B;  4JZF L;  1FSB A;  4X8U L;  2JJL A;  1V1H A;  5CKM A;  2BOH A;  4CUF A;  1PFX L;  3NT1 A;  2VRS A;  3POY A;  3S6X A;  2UWL B;  1LK9 A;  3U73 A;  1F7E A;  2J95 B;  3TK5 B;  4MMY B;  2BSF A;  3ZYI B;  1TOZ A;  1JBU L;  1IGX A;  2HOR A;  4OTY A;  3LN0 A;  3LC5 B;  1F0R B;  2BQW A;  2VH6 B;  2Y5H L;  3TZI A;  4CUE A;  4BTT A;  2Y7X B;  5CIS A;  1X7A L;  2BQ6 A;  4RS0 A;  1ATA A;  3NJP C;  1V1I A;  3HO4 A;  3MDL A;  1CX2 A;  3V65 B;  3HPT A;  2P16 L;  1IQK L;  1PGE A;  2P26 A;  2WPJ E;  4Y71 B;  1IQM L;  3Q3K B;  1G2M B;  1L3Y A;  3V64 C;  1ATB A;  3RR3 A;  4COX A;  2XBY L;  3NTB A;  2YGQ A;  1IQI L;  2H9E C;  3NTG A;  4ISH L;  4Y7B B;  2MGP A;  1DQB A;  2P94 L;  1K36 A;  3SOQ A;  1HAF A;  1G1Q A;  2PR3 B;  2UWP B;  3U7U G;  2EI6 B;  4RRZ A;  1EBV A;  1FAX L;  4D0E A;  3FCS B;  4Z0L A;  1HAE A;  2P3F L;  1F7M A;  2YGP A;  2W3I B;  1EPJ A;  5JBC E;  2WZP P;  1APO A;  1HRF A;  1FE2 A;  2AYL A;  2VJ3 A;  2P3T A;  1MQ6 L;  1DIY A;  1IP0 A;  1EMN A;  5FDQ A;  1UZK A;  4ZH8 B;  2EI8 B;  4X8V L;  3KQC L;  1EPI A;  3LTG D;  1HCG B;  2W2Q E;  2FZZ L;  3HS7 A;  4JZE L;  1LPK A;  1JL9 A;  1WHE A;  4G1M B;  3QCW A;  1IQJ L;  4Y79 B;  2BZ6 L;  3LIW B;  2ADX A;  3C9A C;  1HT8 A;  4PH9 A;  2J38 B;  2JKH L;  2J94 B;  1FFM A;  1Q4G A;  1O5D L;  1W7X L;  3N8V A;  2B7D L;  5CKQ A;  2FLR L;  1KIG L;  4D90 A;  4ZXX L;  3F1S B;  3LAQ A;  1TLE A;  2VH0 B;  2OYE P;  4BDW A;  5JB8 E;  2KL7 A;  2F9B L;  3H5C B;  1ATE A;  1NQL B;  3CFW A;  4Z6A L;  1IGZ A;  4YT7 L;  1FJS L;  1NFY B;  1RFN B;  5KIR A;  3HS5 A;  4C16 A;  2VVV L;  4NGA L;  1XKA L;  2MHP A;  1YUG A;  2BOX A;  1CVW L;  2DDU A;  2XC4 L;  4BDX A;  5JB9 E;  1NFU B;  4XL1 A;  1CEJ A;  1YUF A;  2RHP A;  4RRX A;  4BTU A;  1L5G B;  1N1I A;  4XLW A;  2WG3 C;  1JV2 B;  1EQH A;  1MQ5 L;  2J2U B;  2WYG B;  3OLT A;  1CQE A;  2EI7 B;  5JBB E;  1UZJ A;  2Q1J B;  2W2P E;  3FBY A;  1EPH A;  2MGR A;  1QIU A;  2BOU A;  1IQH L;  3GIS X;  2Y81 B;  2D1J B;  2YGO A;  1ADX A;  1XDT R;  4ZAE B;  2J4I B;  2I9B A;  2M74 A;  2WPM E;  5IKV A;  2XBV L;  3LC3 B;  1LQD A;  2K2S B;  2XBX L;  1Z6E L;  1B9W A;  3ZYJ B;  1UZQ A;  2Y7Z B;  2P3F N; 
#chains in the Genus database with same CATH homology
 3ZYG A;  1TPG A;  1QFK L;  2Y82 B;  2VVU L;  3KRK A;  2XC5 L;  1C5M F;  3N8Y A;  3PGH A;  5KN5 C;  2WG4 B;  1UZP A;  4ISI L;  4O1Z A;  2KV4 A;  3N8Z A;  3ELA L;  1KSN B;  1URK A;  2BMG A;  1XFE A;  5CKN A;  2WYJ B;  1HRE A;  1IVO C;  5IKT A;  3HO3 A;  1U8C B;  1LPG A;  3SOV A;  3KQE L;  1P0S L;  1SZB A;  1J9C L;  2BQ7 A;  5IKR A;  2FLG A;  1PTH A;  4X8S L;  4M11 A;  3BT1 A;  1ATD A;  1FF7 A;  1KLJ L;  2W2O E;  3N8W A;  2WFT A;  5JVY A;  3TGF A;  2XBW L;  3KL6 B;  2W2N E;  1NT0 A;  4NG9 L;  3N8Y B;  1YUK B;  4BXS A;  3QMO A;  6COX A;  4X8T L;  3M37 L;  2FLB L;  5I46 L;  1IOX A;  2Y80 B;  5F1A A;  2W2M E;  1G1S A;  1LPZ A;  3KQB L;  1HX2 A;  1IQE L;  4NA9 L;  1K37 A;  4XBM A;  2PHB B;  1OB1 C;  1EMO A;  1IOE L;  3ASI A;  3CEN L;  1IQG L;  1NFW B;  2VWM K;  4MMZ B;  1LMM A;  5E8D A;  5L2Z L;  2Y5G L;  2W86 A;  3GCX E;  2P3U A;  3HS6 A;  3CA7 A;  3HO5 A;  4AQT A;  2I9A A;  2VWN L;  1F0S B;  1DDX A;  4ZXY L;  2WPL E;  1HZ8 A;  5F19 A;  1BF9 A;  2RA0 L;  1MOX C;  1YGC L;  2KB9 A;  4Y6D B;  3LN1 A;  1GK5 A;  3TH3 L;  3N8X A;  4O02 B;  2WFX B;  1APQ A;  3IJE B;  1U67 A;  1EQG A;  1CCF A;  2K2T A;  1KLI L;  4FM5 A;  4TGF A;  5JBA E;  2WPH E;  3FFG L;  2WPI E;  5IKQ A;  2Y38 A;  3DEM A;  1IQN L;  1KLO A;  3KQD L;  5JVZ A;  4LMF A;  1CCV A;  1LMJ A;  1WHF A;  1A3P A;  3LTF B;  1PRH A;  4RRW A;  4Z0K B;  5JW1 A;  5EGM B;  1ZAQ A;  2BO2 A;  5COX A;  3F6U L;  4JYU L;  4ZHA B;  4RRY A;  5L30 L;  4BXW A;  1P9J A;  1XKB A;  4LOR A;  5L2Y L;  1NZI A;  3BT2 A;  1IJQ A;  4YT6 L;  4E1G A;  1G1R A;  1M1X B;  1N7D A;  1YO8 A;  3BPS E;  1COU A;  1EGF A;  3SW2 A;  1NPE B;  1AUT L;  4OTJ A;  3P5B L;  3CS7 L;  2PUQ L;  4JYV L;  4CUD A;  5K0H B;  4Y76 B;  2W3K B;  2WPK E;  1IQF L;  1EAI C;  2J34 B;  2KNI A;  2CJI B;  2VWO L;  3TBD A;  3KK6 A;  4RUT A;  2GD4 A;  1G2L B;  2H9E L;  3M36 L;  1Z6C A;  4A7I A;  1G1T A;  1PXX A;  1DX5 I;  1V3X B;  2P28 B;  2NPR A;  4CSY A;  2RNL A;  2Y5F L;  1W8B L;  3IIT B;  2P95 L;  4JZD L;  4M10 A;  3TK6 B;  1I0U A;  1EPG A;  4MMX B;  2UWO B;  3GCW E;  3ENS A;  1HJ7 A;  3OLU A;  1EZQ B;  3K9X A;  4Y7A B;  2P93 L;  4D0F A;  4A94 C;  1WU1 B;  2XC0 L;  2FD6 A;  1HT5 A;  1IQL L;  2TGF A;  3KCG L;  2G00 L;  4YZU B;  2BOK L;  2VVC K;  4BTI A;  2OYU P;  2W26 B;  3Q7D A;  3SOB B;  3EGF A;  3N8W B;  1CVU A;  3MQE A;  3QH0 A;  1FAK L;  1DVA L;  2VWL L;  3R05 A;  1NFX B;  4JZF L;  1FSB A;  4X8U L;  5CKM A;  2BOH A;  4CUF A;  1PFX L;  3NT1 A;  3POY A;  3S6X A;  2UWL B;  1F7E A;  3U73 A;  2J95 B;  3TK5 B;  4MMY B;  3ZYI B;  1TOZ A;  1JBU L;  1IGX A;  4OTY A;  3LN0 A;  3LC5 B;  1F0R B;  2BQW A;  2VH6 B;  2Y5H L;  3TZI A;  4CUE A;  4BTT A;  2Y7X B;  5CIS A;  1X7A L;  2BQ6 A;  4RS0 A;  1ATA A;  3NJP C;  3HO4 A;  3MDL A;  1CX2 A;  3V65 B;  3HPT A;  2P16 L;  1IQK L;  1PGE A;  2P26 A;  2WPJ E;  4Y71 B;  1IQM L;  3Q3K B;  1G2M B;  1L3Y A;  3V64 C;  1ATB A;  3RR3 A;  4COX A;  2XBY L;  3NTB A;  2YGQ A;  1IQI L;  2H9E C;  3NTG A;  4ISH L;  4Y7B B;  2MGP A;  1DQB A;  2P94 L;  1K36 A;  3SOQ A;  1HAF A;  1G1Q A;  2PR3 B;  2UWP B;  3U7U G;  2EI6 B;  4RRZ A;  1EBV A;  1FAX L;  4D0E A;  3FCS B;  4Z0L A;  1HAE A;  2P3F L;  1F7M A;  2YGP A;  2W3I B;  1EPJ A;  5JBC E;  2WZP P;  1APO A;  1HRF A;  1FE2 A;  2AYL A;  2VJ3 A;  2P3T A;  1MQ6 L;  1DIY A;  1IP0 A;  1EMN A;  5FDQ A;  1UZK A;  4ZH8 B;  2EI8 B;  4X8V L;  3KQC L;  1EPI A;  3LTG D;  1HCG B;  2W2Q E;  2FZZ L;  3HS7 A;  4JZE L;  1LPK A;  1JL9 A;  1WHE A;  4G1M B;  3QCW A;  1IQJ L;  4Y79 B;  2BZ6 L;  3LIW B;  2ADX A;  3C9A C;  1HT8 A;  4PH9 A;  2J38 B;  2JKH L;  2J94 B;  1FFM A;  1Q4G A;  1O5D L;  1W7X L;  3N8V A;  2B7D L;  5CKQ A;  2FLR L;  1KIG L;  4D90 A;  4ZXX L;  3F1S B;  3LAQ A;  1TLE A;  2VH0 B;  2OYE P;  4BDW A;  5JB8 E;  2KL7 A;  2F9B L;  3H5C B;  1ATE A;  1NQL B;  3CFW A;  4Z6A L;  1IGZ A;  4YT7 L;  1FJS L;  1NFY B;  1RFN B;  5KIR A;  3HS5 A;  4C16 A;  2VVV L;  4NGA L;  1XKA L;  2MHP A;  1YUG A;  2BOX A;  1CVW L;  2DDU A;  2XC4 L;  4BDX A;  5JB9 E;  1NFU B;  4XL1 A;  1CEJ A;  1YUF A;  2RHP A;  4RRX A;  4BTU A;  1L5G B;  1N1I A;  4XLW A;  2WG3 C;  1JV2 B;  1EQH A;  1MQ5 L;  2J2U B;  2WYG B;  3OLT A;  1CQE A;  2EI7 B;  5JBB E;  1UZJ A;  2Q1J B;  2W2P E;  3FBY A;  1EPH A;  2MGR A;  2BOU A;  1IQH L;  3GIS X;  2Y81 B;  2D1J B;  2YGO A;  1ADX A;  1XDT R;  4ZAE B;  2J4I B;  2I9B A;  2M74 A;  2WPM E;  5IKV A;  2XBV L;  3LC3 B;  1LQD A;  2K2S B;  2XBX L;  1Z6E L;  1B9W A;  3ZYJ B;  1UZQ A;  2Y7Z B;  2P3F N; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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