2WPIE

Factor ixa superactive double mutant
Total Genus 9
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
59
structure length
59
Chain Sequence
TCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of the Cofactor- and Substrate-Assisted Activation of Human Coagulation Factor Ixa
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords COAGULATION FACTOR IXA LIGHT CHAIN
total genus 9
structure length 59
sequence length 59
ec nomenclature ec 3.4.21.22: Coagulation factor IXa.
pdb deposition date 2009-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2wpiE00
3ZYGA 1L5GB 1TLEA 1WHEA 2MGPA 2Q1JB 3LTGD 3TGFA 2FD6A 2BZ6L 1KIGL 1F0RB 1YUGA 3DEMA 3N8WA 1PRHA 2VWMK 3V65B 2J2UB 3KL6B 4JZFL 1XDTR 3TZIA 3U73A 5JB9E 3SW2A 3CS7L 4CUDA 5JBCE 1FFMA 1F7MA 1EBVA 3F6UL 4PH9A 3NJPC 1DIYA 2WFXB 1IQNL 2WG4B 5FDQA 2XBVL 3KK6A 1V3XB 2J34B 2JKHL 3N8YB 1CX2A 1NZIA 4Y7AB 1EMOA 2MGRA 2KL7A 1IQIL 3FBYA 1Q4GA 4G1MB 1NT0A 1C5MF 2VWNL 3KCGL 4BTIA 4JYUL 1Z6CA 2Y5HL 2W86A 5JW1A 2WPKE 2Y5GL 5IKQA 1DX5I 4FM5A 1DVAL 4MMXB 3R05A 2J95B 3CA7A 1HZ8A 3N8YA 2XBXL 4O1ZA 1IQLL 1YUFA 1K37A 3GCXE 4OTYA 2XBWL 2WYGB 5KN5C 3QH0A 4X8UL 1AUTL 1IOEL 1U67A 2PUQL 1CVWL 1TOZA 1ADXA 3N8ZA 4Y79B 3MQEA 2W26B 2W3IB 1EZQB 4NA9L 2WPLE 1CQEA 2M74A 2BQ6A 1KLJL 1B9WA 5IKVA 5CISA 1KLIL 2DDUA 1WU1B 3QMOA 4Z6AL 2EI8B 3HPTA 1TPGA 2PR3B 3M36L 1EAIC 2P94L 3IJEB 4LMFA 2W2ME 3EGFA 2PHBB 4BXWA 1G1QA 4RRWA 2I9BA 4CUFA 4RRZA 1HCGB 4D0FA 2H9EL 3N8WB 1HAEA 5JVYA 2FLBL 2OYEP 1APQA 3LC3B 1JL9A 1MQ6L 2Y38A 4YT7L 5K0HB 5F19A 1IGZA 4OTJA 4JZDL 4M10A 4XBMA 1J9CL 5JB8E 2GD4A 1YGCL 2WFTA 3M37L 1EQGA 1UZPA 2I9AA 2FLRL 3NTBA 4Y7BB 1HREA 1EQHA 1HAFA 2P95L 2P26A 2P3FN 5IKTA 1N1IA 4C16A 1ZAQA 1FAKL 1IQGL 1OB1C 2UWLB 3HS7A 1NFUB 1NPEB 4ZXYL 3FCSB 2WPME 1G1SA 1W7XL 5I46L 1NFXB 3ASIA 1UZQA 2XC0L 1HX2A 1WHFA 2KB9A 1CCVA 4ZHAB 5E8DA 3OLTA 3LN1A 1HRFA 2VH6B 2VVUL 4MMYB 4LORA 2AYLA 1XKBA 2WYJB 3TK6B 3ZYJB 3KRKA 4MMZB 1XFEA 2BOKL 2WPJE 3FFGL 5KIRA 4XLWA 2P28B 2XBYL 2BO2A 2YGPA 3BT2A 1GK5A 4RS0A 2J4IB 2RA0L 5JVZA 3HS6A 2UWOB 2WG3C 1APOA 1I0UA 1L3YA 1EMNA 1IOXA 2W2QE 2Y7ZB 2FZZL 2W3KB 2K2TA 1N7DA 2W2NE 5JBAE 1HJ7A 3SOVA 4JZEL 3KQEL 4Y76B 1EGFA 3SOQA 1IJQA 4XL1A 1ATEA 1PGEA 1IQFL 1SZBA 3ELAL 2RNLA 3U7UG 1UZKA 1PXXA 2Y7XB 3LTFB 2J94B 4E1GA 2NPRA 2XC4L 2BMGA 2P3UA 5CKMA 3LAQA 3GCWE 3CENL 3HO3A 1ATAA 3H5CB 2EI7B 1NFYB 1RFNB 4Z0LA 1BF9A 1IQHL 3K9XA 4YZUB 2WPHE 1M1XB 1IQKL 1QFKL 3KQDL 4ZH8B 1HT5A 1IQJL 2OYUP 3CFWA 1EPGA 3C9AC 3LC5B 2Y81B 1F0SB 1HT8A 4COXA 4YT6L 3N8VA 2BQWA 3OLUA 2RHPA 3MDLA 3POYA 1IQML 4Y71B 4ISIL 1JV2B 4BDWA 5JBBE 4X8TL 1DDXA 2EI6B 1G1RA 2Y5FL 4Y6DB 2W2PE 1IQEL 2B7DL 5COXA 1PFXL 3NTGA 5EGMB 1PTHA 2VWOL 2BOHA 2G00L 5CKNA 2BOXA 1JBUL 5F1AA 4X8SL 3TH3L 4D90A 2Y82B 4RUTA 3GISX 3NT1A 4BXSA 4TGFA 1U8CB 3QCWA 2UWPB 1MQ5L 4BDXA 3SOBB 1MOXC 1IGXA 5L2ZL 1P9JA 3HS5A 3ZYIB 5L2YL 2YGOA 1X7AL 1FE2A 3Q3KB 1URKA 3Q7DA 4Z0KB 1A3PA 2CJIB 3BPSE 4X8VL 1G1TA 1YO8A 2XC5L 2VWLL 4BTUA 2ADXA 3BT1A 2D1JB 3LIWB 4NG9L 1EPIA 2KV4A 4D0EA 2BQ7A 1KSNB 2MHPA 2FLGA 1FSBA 2F9BL 4ZAEB 2VVCK 1LPGA 3F1SB 3V64C 3ENSA 1FJSL 1CCFA 4RRXA 2J38B 1ATBA 2TGFA 1YUKB 1XKAL 5L30L 4ISHL 3N8XA 1O5DL 1ATDA 5CKQA 4A7IA 2P3TA 1LQDA 2P3FL 1NQLB 1LMJA 3TK5B 2P16L 1G2MB 3KQCL 1FF7A 1G2LB 1W8BL 3IITB 6COXA 1EPJA 2WPIE 2VVVL 1CEJA 4AQTA 4O02B 2VJ3A 1DQBA 1EPHA 2K2SB 4NGAL 1FAXL 2P93L 1LPKA 5IKRA 3KQBL 3HO5A 3LN0A 1NFWB 4ZXXL 2W2OE 3RR3A 1P0SL 1COUA 1IP0A 1IVOC 4CUEA 1Z6EL 2Y80B 1F7EA 4RRYA 4CSYA 1LPZA 3PGHA 1KLOA 4BTTA 2BOUA 1K36A 1UZJA 3HO4A 1CVUA 2VH0B 3TBDA 3P5BL 4JYVL 4M11A
chains in the Genus database with same CATH superfamily
3ZYGA 1L5GB 1TLEA 1WHEA 2MGPA 1V1IA 2Q1JB 3LTGD 3TGFA 2FD6A 2BZ6L 1KIGL 1F0RB 1YUGA 2BSFA 3DEMA 3N8WA 1PRHA 2VWMK 3V65B 2J2UB 3KL6B 4JZFL 1XDTR 3TZIA 3U73A 5JB9E 3SW2A 3CS7L 4CUDA 5JBCE 1FFMA 1F7MA 1EBVA 3F6UL 2WZPP 4PH9A 3NJPC 1DIYA 2WFXB 1IQNL 2WG4B 5FDQA 2XBVL 3KK6A 1V3XB 2J34B 2JKHL 3N8YB 1CX2A 1NZIA 4Y7AB 1EMOA 2MGRA 2KL7A 1IQIL 3FBYA 1Q4GA 4G1MB 1NT0A 1C5MF 2VWNL 3KCGL 4BTIA 4JYUL 1Z6CA 2Y5HL 2W86A 5JW1A 2WPKE 2Y5GL 5IKQA 1DX5I 4FM5A 1DVAL 4MMXB 3R05A 2J95B 3CA7A 1HZ8A 3N8YA 2XBXL 4O1ZA 1IQLL 1YUFA 1K37A 3GCXE 4OTYA 2XBWL 2BT8A 2WYGB 5KN5C 3QH0A 4X8UL 1AUTL 1IOEL 1U67A 2PUQL 1CVWL 1TOZA 1ADXA 3N8ZA 4Y79B 3MQEA 2W26B 2W3IB 1EZQB 4NA9L 2WPLE 1CQEA 2M74A 2BQ6A 1KLJL 1B9WA 5IKVA 5CISA 1KLIL 2DDUA 1WU1B 3QMOA 4Z6AL 2EI8B 3HPTA 1TPGA 2PR3B 3M36L 1EAIC 2P94L 3IJEB 4LMFA 2W2ME 3EGFA 2PHBB 4BXWA 1G1QA 4RRWA 2I9BA 4CUFA 4RRZA 1HCGB 4GU4A 4D0FA 2H9EL 3N8WB 1HAEA 5JVYA 2FLBL 2OYEP 1APQA 3LC3B 1JL9A 1MQ6L 2Y38A 4YT7L 1V1HA 5K0HB 5F19A 1IGZA 4OTJA 2KNIA 4JZDL 4M10A 4XBMA 1J9CL 5JB8E 2GD4A 1YGCL 2WFTA 3M37L 1EQGA 1UZPA 2I9AA 2FLRL 3NTBA 4Y7BB 1HREA 2H9EC 1EQHA 1HAFA 4A94C 2P95L 4GU3A 2P26A 2P3FN 5IKTA 1N1IA 4C16A 1ZAQA 1FAKL 1IQGL 1OB1C 2UWLB 3HS7A 1NFUB 1NPEB 4ZXYL 3FCSB 2WPME 1G1SA 1W7XL 5I46L 1NFXB 3ASIA 1UZQA 1KKEA 2XC0L 1HX2A 1WHFA 2KB9A 1CCVA 4ZHAB 5E8DA 3OLTA 3LN1A 1HRFA 2VH6B 2VVUL 4MMYB 4LORA 2AYLA 1XKBA 2WYJB 3TK6B 3ZYJB 3KRKA 4MMZB 1XFEA 2BOKL 2WPJE 3FFGL 5KIRA 4XLWA 2P28B 2XBYL 2BO2A 2YGPA 3BT2A 1GK5A 4RS0A 2J4IB 2RA0L 5JVZA 3HS6A 2UWOB 2WG3C 1APOA 1I0UA 1L3YA 1EMNA 1IOXA 2W2QE 2Y7ZB 2FZZL 2W3KB 2K2TA 1N7DA 2W2NE 5JBAE 1HJ7A 3SOVA 4JZEL 3KQEL 4Y76B 2HORA 1EGFA 3SOQA 1IJQA 4XL1A 1ATEA 1PGEA 1IQFL 1SZBA 3ELAL 2RNLA 3U7UG 1UZKA 1PXXA 2Y7XB 3LTFB 2J94B 4E1GA 2NPRA 2XC4L 2BMGA 2P3UA 5CKMA 3LAQA 3GCWE 3CENL 3HO3A 1ATAA 3H5CB 2EI7B 1NFYB 1RFNB 4Z0LA 1BF9A 1IQHL 3K9XA 4YZUB 2WPHE 1M1XB 1IQKL 1QFKL 3KQDL 4ZH8B 1HT5A 1IQJL 2OYUP 3CFWA 1EPGA 3C9AC 3LC5B 2Y81B 1F0SB 1HT8A 4COXA 4YT6L 3N8VA 2BQWA 3OLUA 2RHPA 3MDLA 3POYA 1IQML 4Y71B 4ISIL 1JV2B 4BDWA 5JBBE 4X8TL 1DDXA 2EI6B 1G1RA 2Y5FL 4Y6DB 2W2PE 1IQEL 2B7DL 5COXA 1PFXL 3NTGA 5EGMB 1PTHA 2VWOL 2BOHA 2YGQA 2G00L 5CKNA 2BOXA 1JBUL 5F1AA 4X8SL 3TH3L 4D90A 2Y82B 4RUTA 3GISX 3NT1A 4BXSA 4TGFA 1U8CB 3QCWA 2UWPB 1MQ5L 4BDXA 3SOBB 1MOXC 1IGXA 2BT7A 5L2ZL 1P9JA 3HS5A 1LMMA 3ZYIB 5L2YL 2YGOA 1X7AL 1FE2A 3Q3KB 1URKA 3Q7DA 4Z0KB 1A3PA 2CJIB 3BPSE 4X8VL 1G1TA 1YO8A 2XC5L 2VWLL 4BTUA 2ADXA 3BT1A 2D1JB 3LIWB 4NG9L 1EPIA 2KV4A 4D0EA 1QIUA 2BQ7A 1KSNB 2MHPA 2FLGA 1FSBA 2F9BL 2JJLA 4ZAEB 2VVCK 1LPGA 3F1SB 3V64C 3ENSA 1FJSL 1CCFA 4RRXA 2J38B 1ATBA 2TGFA 1YUKB 1XKAL 5L30L 4ISHL 1LK9A 3N8XA 1O5DL 1ATDA 5CKQA 4A7IA 2P3TA 1LQDA 2P3FL 1NQLB 1LMJA 3TK5B 2P16L 1G2MB 3KQCL 1FF7A 1G2LB 1W8BL 3IITB 3S6XA 6COXA 1EPJA 2WPIE 2VVVL 1CEJA 4AQTA 4O02B 2VJ3A 1DQBA 1EPHA 2K2SB 4NGAL 1FAXL 2P93L 1LPKA 5IKRA 3KQBL 3HO5A 3LN0A 1NFWB 4ZXXL 2W2OE 3RR3A 1P0SL 1COUA 1IP0A 2HOXA 1IVOC 4CUEA 1Z6EL 2Y80B 2VRSA 1F7EA 4RRYA 4CSYA 1LPZA 3PGHA 1KLOA 4BTTA 2BOUA 1K36A 1UZJA 3HO4A 1CVUA 2VH0B 3TBDA 3P5BL 4JYVL 4M11A
chains in the Genus database with same CATH topology
3ZYGA 1L5GB 1TLEA 1WHEA 2MGPA 2Q1JB 3LTGD 3TGFA 2FD6A 2BZ6L 1KIGL 1F0RB 1YUGA 3DEMA 3N8WA 1PRHA 2VWMK 3V65B 2J2UB 3KL6B 4JZFL 1XDTR 3TZIA 3U73A 5JB9E 3SW2A 3CS7L 4CUDA 5JBCE 1FFMA 1F7MA 1EBVA 3F6UL 2WZPP 4PH9A 3NJPC 1DIYA 2WFXB 1IQNL 2WG4B 5FDQA 2XBVL 3KK6A 1V3XB 2J34B 2JKHL 3N8YB 1CX2A 1NZIA 4Y7AB 1EMOA 2MGRA 2KL7A 1IQIL 3FBYA 1Q4GA 4G1MB 1NT0A 1C5MF 2VWNL 3KCGL 4BTIA 4JYUL 1Z6CA 2Y5HL 2W86A 5JW1A 2WPKE 2Y5GL 5IKQA 1DX5I 4FM5A 1DVAL 4MMXB 3R05A 2J95B 3CA7A 1HZ8A 3N8YA 2XBXL 4O1ZA 1IQLL 1YUFA 1K37A 3GCXE 4OTYA 2XBWL 2WYGB 5KN5C 3QH0A 4X8UL 1AUTL 1IOEL 1U67A 2PUQL 1CVWL 1TOZA 1ADXA 3N8ZA 4Y79B 3MQEA 2W26B 2W3IB 1EZQB 4NA9L 2WPLE 1CQEA 2M74A 2BQ6A 1KLJL 1B9WA 5IKVA 5CISA 1KLIL 2DDUA 1WU1B 3QMOA 4Z6AL 2EI8B 3HPTA 1TPGA 2PR3B 3M36L 1EAIC 2P94L 3IJEB 4LMFA 2W2ME 3EGFA 2PHBB 4BXWA 1G1QA 4RRWA 2I9BA 4CUFA 4RRZA 1HCGB 4D0FA 2H9EL 3N8WB 1HAEA 5JVYA 2FLBL 2OYEP 1APQA 3LC3B 1JL9A 1MQ6L 2Y38A 4YT7L 5K0HB 5F19A 1IGZA 4OTJA 2KNIA 4JZDL 4M10A 4XBMA 1J9CL 5JB8E 2GD4A 1YGCL 2WFTA 3M37L 1EQGA 1UZPA 2I9AA 2FLRL 3NTBA 4Y7BB 1HREA 2H9EC 1EQHA 1HAFA 4A94C 2P95L 2P26A 2P3FN 5IKTA 1N1IA 4C16A 1ZAQA 1FAKL 1IQGL 1OB1C 2UWLB 3HS7A 1NFUB 1NPEB 4ZXYL 3FCSB 2WPME 1G1SA 1W7XL 5I46L 1NFXB 3ASIA 1UZQA 2XC0L 1HX2A 1WHFA 2KB9A 1CCVA 4ZHAB 5E8DA 3OLTA 3LN1A 1HRFA 2VH6B 2VVUL 4MMYB 4LORA 2AYLA 1XKBA 2WYJB 3TK6B 3ZYJB 3KRKA 4MMZB 1XFEA 2BOKL 2WPJE 3FFGL 5KIRA 4XLWA 2P28B 2XBYL 2BO2A 2YGPA 3BT2A 1GK5A 4RS0A 2J4IB 2RA0L 5JVZA 3HS6A 2UWOB 2WG3C 1APOA 1I0UA 1L3YA 1EMNA 1IOXA 2W2QE 2Y7ZB 2FZZL 2W3KB 2K2TA 1N7DA 2W2NE 5JBAE 1HJ7A 3SOVA 4JZEL 3KQEL 4Y76B 1EGFA 3SOQA 1IJQA 4XL1A 1ATEA 1PGEA 1IQFL 1SZBA 3ELAL 2RNLA 3U7UG 1UZKA 1PXXA 2Y7XB 3LTFB 2J94B 4E1GA 2NPRA 2XC4L 2BMGA 2P3UA 5CKMA 3LAQA 3GCWE 3CENL 3HO3A 1ATAA 3H5CB 2EI7B 1NFYB 1RFNB 4Z0LA 1BF9A 1IQHL 3K9XA 4YZUB 2WPHE 1M1XB 1IQKL 1QFKL 3KQDL 4ZH8B 1HT5A 1IQJL 2OYUP 3CFWA 1EPGA 3C9AC 3LC5B 2Y81B 1F0SB 1HT8A 4COXA 4YT6L 3N8VA 2BQWA 3OLUA 2RHPA 3MDLA 3POYA 1IQML 4Y71B 4ISIL 1JV2B 4BDWA 5JBBE 4X8TL 1DDXA 2EI6B 1G1RA 2Y5FL 4Y6DB 2W2PE 1IQEL 2B7DL 5COXA 1PFXL 3NTGA 5EGMB 1PTHA 2VWOL 2BOHA 2YGQA 2G00L 5CKNA 2BOXA 1JBUL 5F1AA 4X8SL 3TH3L 4D90A 2Y82B 4RUTA 3GISX 3NT1A 4BXSA 4TGFA 1U8CB 3QCWA 2UWPB 1MQ5L 4BDXA 3SOBB 1MOXC 1IGXA 5L2ZL 1P9JA 3HS5A 1LMMA 3ZYIB 5L2YL 2YGOA 1X7AL 1FE2A 3Q3KB 1URKA 3Q7DA 4Z0KB 1A3PA 2CJIB 3BPSE 4X8VL 1G1TA 1YO8A 2XC5L 2VWLL 4BTUA 2ADXA 3BT1A 2D1JB 3LIWB 4NG9L 1EPIA 2KV4A 4D0EA 2BQ7A 1KSNB 2MHPA 2FLGA 1FSBA 2F9BL 4ZAEB 2VVCK 1LPGA 3F1SB 3V64C 3ENSA 1FJSL 1CCFA 4RRXA 2J38B 1ATBA 2TGFA 1YUKB 1XKAL 5L30L 4ISHL 3N8XA 1O5DL 1ATDA 5CKQA 4A7IA 2P3TA 1LQDA 2P3FL 1NQLB 1LMJA 3TK5B 2P16L 1G2MB 3KQCL 1FF7A 1G2LB 1W8BL 3IITB 3S6XA 6COXA 1EPJA 2WPIE 2VVVL 1CEJA 4AQTA 4O02B 2VJ3A 1DQBA 1EPHA 2K2SB 4NGAL 1FAXL 2P93L 1LPKA 5IKRA 3KQBL 3HO5A 3LN0A 1NFWB 4ZXXL 2W2OE 3RR3A 1P0SL 1COUA 1IP0A 1IVOC 4CUEA 1Z6EL 2Y80B 1F7EA 4RRYA 4CSYA 1LPZA 3PGHA 1KLOA 4BTTA 2BOUA 1K36A 1UZJA 3HO4A 1CVUA 2VH0B 3TBDA 3P5BL 4JYVL 4M11A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZYG A;  1L5G B;  1TLE A;  1WHE A;  2MGP A;  2Q1J B;  3LTG D;  3TGF A;  2FD6 A;  2BZ6 L;  1KIG L;  1F0R B;  1YUG A;  3DEM A;  3N8W A;  1PRH A;  2VWM K;  3V65 B;  2J2U B;  3KL6 B;  4JZF L;  1XDT R;  3TZI A;  3U73 A;  5JB9 E;  3SW2 A;  3CS7 L;  4CUD A;  5JBC E;  1FFM A;  1F7M A;  1EBV A;  3F6U L;  4PH9 A;  3NJP C;  1DIY A;  2WFX B;  1IQN L;  2WG4 B;  5FDQ A;  2XBV L;  3KK6 A;  1V3X B;  2J34 B;  2JKH L;  3N8Y B;  1CX2 A;  1NZI A;  4Y7A B;  1EMO A;  2MGR A;  2KL7 A;  1IQI L;  3FBY A;  1Q4G A;  4G1M B;  1NT0 A;  1C5M F;  2VWN L;  3KCG L;  4BTI A;  4JYU L;  1Z6C A;  2Y5H L;  2W86 A;  5JW1 A;  2WPK E;  2Y5G L;  5IKQ A;  1DX5 I;  4FM5 A;  1DVA L;  4MMX B;  3R05 A;  2J95 B;  3CA7 A;  1HZ8 A;  3N8Y A;  2XBX L;  4O1Z A;  1IQL L;  1YUF A;  1K37 A;  3GCX E;  4OTY A;  2XBW L;  2WYG B;  5KN5 C;  3QH0 A;  4X8U L;  1AUT L;  1IOE L;  1U67 A;  2PUQ L;  1CVW L;  1TOZ A;  1ADX A;  3N8Z A;  4Y79 B;  3MQE A;  2W26 B;  2W3I B;  1EZQ B;  4NA9 L;  2WPL E;  1CQE A;  2M74 A;  2BQ6 A;  1KLJ L;  1B9W A;  5IKV A;  5CIS A;  1KLI L;  2DDU A;  1WU1 B;  3QMO A;  4Z6A L;  2EI8 B;  3HPT A;  1TPG A;  2PR3 B;  3M36 L;  1EAI C;  2P94 L;  3IJE B;  4LMF A;  2W2M E;  3EGF A;  2PHB B;  4BXW A;  1G1Q A;  4RRW A;  2I9B A;  4CUF A;  4RRZ A;  1HCG B;  4D0F A;  2H9E L;  3N8W B;  1HAE A;  5JVY A;  2FLB L;  2OYE P;  1APQ A;  3LC3 B;  1JL9 A;  1MQ6 L;  2Y38 A;  4YT7 L;  5K0H B;  5F19 A;  1IGZ A;  4OTJ A;  4JZD L;  4M10 A;  4XBM A;  1J9C L;  5JB8 E;  2GD4 A;  1YGC L;  2WFT A;  3M37 L;  1EQG A;  1UZP A;  2I9A A;  2FLR L;  3NTB A;  4Y7B B;  1HRE A;  1EQH A;  1HAF A;  2P95 L;  2P26 A;  2P3F N;  5IKT A;  1N1I A;  4C16 A;  1ZAQ A;  1FAK L;  1IQG L;  1OB1 C;  2UWL B;  3HS7 A;  1NFU B;  1NPE B;  4ZXY L;  3FCS B;  2WPM E;  1G1S A;  1W7X L;  5I46 L;  1NFX B;  3ASI A;  1UZQ A;  2XC0 L;  1HX2 A;  1WHF A;  2KB9 A;  1CCV A;  4ZHA B;  5E8D A;  3OLT A;  3LN1 A;  1HRF A;  2VH6 B;  2VVU L;  4MMY B;  4LOR A;  2AYL A;  1XKB A;  2WYJ B;  3TK6 B;  3ZYJ B;  3KRK A;  4MMZ B;  1XFE A;  2BOK L;  2WPJ E;  3FFG L;  5KIR A;  4XLW A;  2P28 B;  2XBY L;  2BO2 A;  2YGP A;  3BT2 A;  1GK5 A;  4RS0 A;  2J4I B;  2RA0 L;  5JVZ A;  3HS6 A;  2UWO B;  2WG3 C;  1APO A;  1I0U A;  1L3Y A;  1EMN A;  1IOX A;  2W2Q E;  2Y7Z B;  2FZZ L;  2W3K B;  2K2T A;  1N7D A;  2W2N E;  5JBA E;  1HJ7 A;  3SOV A;  4JZE L;  3KQE L;  4Y76 B;  1EGF A;  3SOQ A;  1IJQ A;  4XL1 A;  1ATE A;  1PGE A;  1IQF L;  1SZB A;  3ELA L;  2RNL A;  3U7U G;  1UZK A;  1PXX A;  2Y7X B;  3LTF B;  2J94 B;  4E1G A;  2NPR A;  2XC4 L;  2BMG A;  2P3U A;  5CKM A;  3LAQ A;  3GCW E;  3CEN L;  3HO3 A;  1ATA A;  3H5C B;  2EI7 B;  1NFY B;  1RFN B;  4Z0L A;  1BF9 A;  1IQH L;  3K9X A;  4YZU B;  2WPH E;  1M1X B;  1IQK L;  1QFK L;  3KQD L;  4ZH8 B;  1HT5 A;  1IQJ L;  2OYU P;  3CFW A;  1EPG A;  3C9A C;  3LC5 B;  2Y81 B;  1F0S B;  1HT8 A;  4COX A;  4YT6 L;  3N8V A;  2BQW A;  3OLU A;  2RHP A;  3MDL A;  3POY A;  1IQM L;  4Y71 B;  4ISI L;  1JV2 B;  4BDW A;  5JBB E;  4X8T L;  1DDX A;  2EI6 B;  1G1R A;  2Y5F L;  4Y6D B;  2W2P E;  1IQE L;  2B7D L;  5COX A;  1PFX L;  3NTG A;  5EGM B;  1PTH A;  2VWO L;  2BOH A;  2G00 L;  5CKN A;  2BOX A;  1JBU L;  5F1A A;  4X8S L;  3TH3 L;  4D90 A;  2Y82 B;  4RUT A;  3GIS X;  3NT1 A;  4BXS A;  4TGF A;  1U8C B;  3QCW A;  2UWP B;  1MQ5 L;  4BDX A;  3SOB B;  1MOX C;  1IGX A;  5L2Z L;  1P9J A;  3HS5 A;  3ZYI B;  5L2Y L;  2YGO A;  1X7A L;  1FE2 A;  3Q3K B;  1URK A;  3Q7D A;  4Z0K B;  1A3P A;  2CJI B;  3BPS E;  4X8V L;  1G1T A;  1YO8 A;  2XC5 L;  2VWL L;  4BTU A;  2ADX A;  3BT1 A;  2D1J B;  3LIW B;  4NG9 L;  1EPI A;  2KV4 A;  4D0E A;  2BQ7 A;  1KSN B;  2MHP A;  2FLG A;  1FSB A;  2F9B L;  4ZAE B;  2VVC K;  1LPG A;  3F1S B;  3V64 C;  3ENS A;  1FJS L;  1CCF A;  4RRX A;  2J38 B;  1ATB A;  2TGF A;  1YUK B;  1XKA L;  5L30 L;  4ISH L;  3N8X A;  1O5D L;  1ATD A;  5CKQ A;  4A7I A;  2P3T A;  1LQD A;  2P3F L;  1NQL B;  1LMJ A;  3TK5 B;  2P16 L;  1G2M B;  3KQC L;  1FF7 A;  1G2L B;  1W8B L;  3IIT B;  6COX A;  1EPJ A;  2WPI E;  2VVV L;  1CEJ A;  4AQT A;  4O02 B;  2VJ3 A;  1DQB A;  1EPH A;  2K2S B;  4NGA L;  1FAX L;  2P93 L;  1LPK A;  5IKR A;  3KQB L;  3HO5 A;  3LN0 A;  1NFW B;  4ZXX L;  2W2O E;  3RR3 A;  1P0S L;  1COU A;  1IP0 A;  1IVO C;  4CUE A;  1Z6E L;  2Y80 B;  1F7E A;  4RRY A;  4CSY A;  1LPZ A;  3PGH A;  1KLO A;  4BTT A;  2BOU A;  1K36 A;  1UZJ A;  3HO4 A;  1CVU A;  2VH0 B;  3TBD A;  3P5B L;  4JYV L;  4M11 A; 
#chains in the Genus database with same CATH topology
 3ZYG A;  1L5G B;  1TLE A;  1WHE A;  2MGP A;  1V1I A;  2Q1J B;  3LTG D;  3TGF A;  2FD6 A;  2BZ6 L;  1KIG L;  1F0R B;  1YUG A;  2BSF A;  3DEM A;  3N8W A;  1PRH A;  2VWM K;  3V65 B;  2J2U B;  3KL6 B;  4JZF L;  1XDT R;  3TZI A;  3U73 A;  5JB9 E;  3SW2 A;  3CS7 L;  4CUD A;  5JBC E;  1FFM A;  1F7M A;  1EBV A;  3F6U L;  2WZP P;  4PH9 A;  3NJP C;  1DIY A;  2WFX B;  1IQN L;  2WG4 B;  5FDQ A;  2XBV L;  3KK6 A;  1V3X B;  2J34 B;  2JKH L;  3N8Y B;  1CX2 A;  1NZI A;  4Y7A B;  1EMO A;  2MGR A;  2KL7 A;  1IQI L;  3FBY A;  1Q4G A;  4G1M B;  1NT0 A;  1C5M F;  2VWN L;  3KCG L;  4BTI A;  4JYU L;  1Z6C A;  2Y5H L;  2W86 A;  5JW1 A;  2WPK E;  2Y5G L;  5IKQ A;  1DX5 I;  4FM5 A;  1DVA L;  4MMX B;  3R05 A;  2J95 B;  3CA7 A;  1HZ8 A;  3N8Y A;  2XBX L;  4O1Z A;  1IQL L;  1YUF A;  1K37 A;  3GCX E;  4OTY A;  2XBW L;  2BT8 A;  2WYG B;  5KN5 C;  3QH0 A;  4X8U L;  1AUT L;  1IOE L;  1U67 A;  2PUQ L;  1CVW L;  1TOZ A;  1ADX A;  3N8Z A;  4Y79 B;  3MQE A;  2W26 B;  2W3I B;  1EZQ B;  4NA9 L;  2WPL E;  1CQE A;  2M74 A;  2BQ6 A;  1KLJ L;  1B9W A;  5IKV A;  5CIS A;  1KLI L;  2DDU A;  1WU1 B;  3QMO A;  4Z6A L;  2EI8 B;  3HPT A;  1TPG A;  2PR3 B;  3M36 L;  1EAI C;  2P94 L;  3IJE B;  4LMF A;  2W2M E;  3EGF A;  2PHB B;  4BXW A;  1G1Q A;  4RRW A;  2I9B A;  4CUF A;  4RRZ A;  1HCG B;  4GU4 A;  4D0F A;  2H9E L;  3N8W B;  1HAE A;  5JVY A;  2FLB L;  2OYE P;  1APQ A;  3LC3 B;  1JL9 A;  1MQ6 L;  2Y38 A;  4YT7 L;  1V1H A;  5K0H B;  5F19 A;  1IGZ A;  4OTJ A;  2KNI A;  4JZD L;  4M10 A;  4XBM A;  1J9C L;  5JB8 E;  2GD4 A;  1YGC L;  2WFT A;  3M37 L;  1EQG A;  1UZP A;  2I9A A;  2FLR L;  3NTB A;  4Y7B B;  1HRE A;  2H9E C;  1EQH A;  1HAF A;  4A94 C;  2P95 L;  4GU3 A;  2P26 A;  2P3F N;  5IKT A;  1N1I A;  4C16 A;  1ZAQ A;  1FAK L;  1IQG L;  1OB1 C;  2UWL B;  3HS7 A;  1NFU B;  1NPE B;  4ZXY L;  3FCS B;  2WPM E;  1G1S A;  1W7X L;  5I46 L;  1NFX B;  3ASI A;  1UZQ A;  1KKE A;  2XC0 L;  1HX2 A;  1WHF A;  2KB9 A;  1CCV A;  4ZHA B;  5E8D A;  3OLT A;  3LN1 A;  1HRF A;  2VH6 B;  2VVU L;  4MMY B;  4LOR A;  2AYL A;  1XKB A;  2WYJ B;  3TK6 B;  3ZYJ B;  3KRK A;  4MMZ B;  1XFE A;  2BOK L;  2WPJ E;  3FFG L;  5KIR A;  4XLW A;  2P28 B;  2XBY L;  2BO2 A;  2YGP A;  3BT2 A;  1GK5 A;  4RS0 A;  2J4I B;  2RA0 L;  5JVZ A;  3HS6 A;  2UWO B;  2WG3 C;  1APO A;  1I0U A;  1L3Y A;  1EMN A;  1IOX A;  2W2Q E;  2Y7Z B;  2FZZ L;  2W3K B;  2K2T A;  1N7D A;  2W2N E;  5JBA E;  1HJ7 A;  3SOV A;  4JZE L;  3KQE L;  4Y76 B;  2HOR A;  1EGF A;  3SOQ A;  1IJQ A;  4XL1 A;  1ATE A;  1PGE A;  1IQF L;  1SZB A;  3ELA L;  2RNL A;  3U7U G;  1UZK A;  1PXX A;  2Y7X B;  3LTF B;  2J94 B;  4E1G A;  2NPR A;  2XC4 L;  2BMG A;  2P3U A;  5CKM A;  3LAQ A;  3GCW E;  3CEN L;  3HO3 A;  1ATA A;  3H5C B;  2EI7 B;  1NFY B;  1RFN B;  4Z0L A;  1BF9 A;  1IQH L;  3K9X A;  4YZU B;  2WPH E;  1M1X B;  1IQK L;  1QFK L;  3KQD L;  4ZH8 B;  1HT5 A;  1IQJ L;  2OYU P;  3CFW A;  1EPG A;  3C9A C;  3LC5 B;  2Y81 B;  1F0S B;  1HT8 A;  4COX A;  4YT6 L;  3N8V A;  2BQW A;  3OLU A;  2RHP A;  3MDL A;  3POY A;  1IQM L;  4Y71 B;  4ISI L;  1JV2 B;  4BDW A;  5JBB E;  4X8T L;  1DDX A;  2EI6 B;  1G1R A;  2Y5F L;  4Y6D B;  2W2P E;  1IQE L;  2B7D L;  5COX A;  1PFX L;  3NTG A;  5EGM B;  1PTH A;  2VWO L;  2BOH A;  2YGQ A;  2G00 L;  5CKN A;  2BOX A;  1JBU L;  5F1A A;  4X8S L;  3TH3 L;  4D90 A;  2Y82 B;  4RUT A;  3GIS X;  3NT1 A;  4BXS A;  4TGF A;  1U8C B;  3QCW A;  2UWP B;  1MQ5 L;  4BDX A;  3SOB B;  1MOX C;  1IGX A;  2BT7 A;  5L2Z L;  1P9J A;  3HS5 A;  1LMM A;  3ZYI B;  5L2Y L;  2YGO A;  1X7A L;  1FE2 A;  3Q3K B;  1URK A;  3Q7D A;  4Z0K B;  1A3P A;  2CJI B;  3BPS E;  4X8V L;  1G1T A;  1YO8 A;  2XC5 L;  2VWL L;  4BTU A;  2ADX A;  3BT1 A;  2D1J B;  3LIW B;  4NG9 L;  1EPI A;  2KV4 A;  4D0E A;  1QIU A;  2BQ7 A;  1KSN B;  2MHP A;  2FLG A;  1FSB A;  2F9B L;  2JJL A;  4ZAE B;  2VVC K;  1LPG A;  3F1S B;  3V64 C;  3ENS A;  1FJS L;  1CCF A;  4RRX A;  2J38 B;  1ATB A;  2TGF A;  1YUK B;  1XKA L;  5L30 L;  4ISH L;  1LK9 A;  3N8X A;  1O5D L;  1ATD A;  5CKQ A;  4A7I A;  2P3T A;  1LQD A;  2P3F L;  1NQL B;  1LMJ A;  3TK5 B;  2P16 L;  1G2M B;  3KQC L;  1FF7 A;  1G2L B;  1W8B L;  3IIT B;  3S6X A;  6COX A;  1EPJ A;  2WPI E;  2VVV L;  1CEJ A;  4AQT A;  4O02 B;  2VJ3 A;  1DQB A;  1EPH A;  2K2S B;  4NGA L;  1FAX L;  2P93 L;  1LPK A;  5IKR A;  3KQB L;  3HO5 A;  3LN0 A;  1NFW B;  4ZXX L;  2W2O E;  3RR3 A;  1P0S L;  1COU A;  1IP0 A;  2HOX A;  1IVO C;  4CUE A;  1Z6E L;  2Y80 B;  2VRS A;  1F7E A;  4RRY A;  4CSY A;  1LPZ A;  3PGH A;  1KLO A;  4BTT A;  2BOU A;  1K36 A;  1UZJ A;  3HO4 A;  1CVU A;  2VH0 B;  3TBD A;  3P5B L;  4JYV L;  4M11 A; 
#chains in the Genus database with same CATH homology
 3ZYG A;  1L5G B;  1TLE A;  1WHE A;  2MGP A;  2Q1J B;  3LTG D;  3TGF A;  2FD6 A;  2BZ6 L;  1KIG L;  1F0R B;  1YUG A;  3DEM A;  3N8W A;  1PRH A;  2VWM K;  3V65 B;  2J2U B;  3KL6 B;  4JZF L;  1XDT R;  3TZI A;  3U73 A;  5JB9 E;  3SW2 A;  3CS7 L;  4CUD A;  5JBC E;  1FFM A;  1F7M A;  1EBV A;  3F6U L;  2WZP P;  4PH9 A;  3NJP C;  1DIY A;  2WFX B;  1IQN L;  2WG4 B;  5FDQ A;  2XBV L;  3KK6 A;  1V3X B;  2J34 B;  2JKH L;  3N8Y B;  1CX2 A;  1NZI A;  4Y7A B;  1EMO A;  2MGR A;  2KL7 A;  1IQI L;  3FBY A;  1Q4G A;  4G1M B;  1NT0 A;  1C5M F;  2VWN L;  3KCG L;  4BTI A;  4JYU L;  1Z6C A;  2Y5H L;  2W86 A;  5JW1 A;  2WPK E;  2Y5G L;  5IKQ A;  1DX5 I;  4FM5 A;  1DVA L;  4MMX B;  3R05 A;  2J95 B;  3CA7 A;  1HZ8 A;  3N8Y A;  2XBX L;  4O1Z A;  1IQL L;  1YUF A;  1K37 A;  3GCX E;  4OTY A;  2XBW L;  2WYG B;  5KN5 C;  3QH0 A;  4X8U L;  1AUT L;  1IOE L;  1U67 A;  2PUQ L;  1CVW L;  1TOZ A;  1ADX A;  3N8Z A;  4Y79 B;  3MQE A;  2W26 B;  2W3I B;  1EZQ B;  4NA9 L;  2WPL E;  1CQE A;  2M74 A;  2BQ6 A;  1KLJ L;  1B9W A;  5IKV A;  5CIS A;  1KLI L;  2DDU A;  1WU1 B;  3QMO A;  4Z6A L;  2EI8 B;  3HPT A;  1TPG A;  2PR3 B;  3M36 L;  1EAI C;  2P94 L;  3IJE B;  4LMF A;  2W2M E;  3EGF A;  2PHB B;  4BXW A;  1G1Q A;  4RRW A;  2I9B A;  4CUF A;  4RRZ A;  1HCG B;  4D0F A;  2H9E L;  3N8W B;  1HAE A;  5JVY A;  2FLB L;  2OYE P;  1APQ A;  3LC3 B;  1JL9 A;  1MQ6 L;  2Y38 A;  4YT7 L;  5K0H B;  5F19 A;  1IGZ A;  4OTJ A;  2KNI A;  4JZD L;  4M10 A;  4XBM A;  1J9C L;  5JB8 E;  2GD4 A;  1YGC L;  2WFT A;  3M37 L;  1EQG A;  1UZP A;  2I9A A;  2FLR L;  3NTB A;  4Y7B B;  1HRE A;  2H9E C;  1EQH A;  1HAF A;  4A94 C;  2P95 L;  2P26 A;  2P3F N;  5IKT A;  1N1I A;  4C16 A;  1ZAQ A;  1FAK L;  1IQG L;  1OB1 C;  2UWL B;  3HS7 A;  1NFU B;  1NPE B;  4ZXY L;  3FCS B;  2WPM E;  1G1S A;  1W7X L;  5I46 L;  1NFX B;  3ASI A;  1UZQ A;  2XC0 L;  1HX2 A;  1WHF A;  2KB9 A;  1CCV A;  4ZHA B;  5E8D A;  3OLT A;  3LN1 A;  1HRF A;  2VH6 B;  2VVU L;  4MMY B;  4LOR A;  2AYL A;  1XKB A;  2WYJ B;  3TK6 B;  3ZYJ B;  3KRK A;  4MMZ B;  1XFE A;  2BOK L;  2WPJ E;  3FFG L;  5KIR A;  4XLW A;  2P28 B;  2XBY L;  2BO2 A;  2YGP A;  3BT2 A;  1GK5 A;  4RS0 A;  2J4I B;  2RA0 L;  5JVZ A;  3HS6 A;  2UWO B;  2WG3 C;  1APO A;  1I0U A;  1L3Y A;  1EMN A;  1IOX A;  2W2Q E;  2Y7Z B;  2FZZ L;  2W3K B;  2K2T A;  1N7D A;  2W2N E;  5JBA E;  1HJ7 A;  3SOV A;  4JZE L;  3KQE L;  4Y76 B;  1EGF A;  3SOQ A;  1IJQ A;  4XL1 A;  1ATE A;  1PGE A;  1IQF L;  1SZB A;  3ELA L;  2RNL A;  3U7U G;  1UZK A;  1PXX A;  2Y7X B;  3LTF B;  2J94 B;  4E1G A;  2NPR A;  2XC4 L;  2BMG A;  2P3U A;  5CKM A;  3LAQ A;  3GCW E;  3CEN L;  3HO3 A;  1ATA A;  3H5C B;  2EI7 B;  1NFY B;  1RFN B;  4Z0L A;  1BF9 A;  1IQH L;  3K9X A;  4YZU B;  2WPH E;  1M1X B;  1IQK L;  1QFK L;  3KQD L;  4ZH8 B;  1HT5 A;  1IQJ L;  2OYU P;  3CFW A;  1EPG A;  3C9A C;  3LC5 B;  2Y81 B;  1F0S B;  1HT8 A;  4COX A;  4YT6 L;  3N8V A;  2BQW A;  3OLU A;  2RHP A;  3MDL A;  3POY A;  1IQM L;  4Y71 B;  4ISI L;  1JV2 B;  4BDW A;  5JBB E;  4X8T L;  1DDX A;  2EI6 B;  1G1R A;  2Y5F L;  4Y6D B;  2W2P E;  1IQE L;  2B7D L;  5COX A;  1PFX L;  3NTG A;  5EGM B;  1PTH A;  2VWO L;  2BOH A;  2YGQ A;  2G00 L;  5CKN A;  2BOX A;  1JBU L;  5F1A A;  4X8S L;  3TH3 L;  4D90 A;  2Y82 B;  4RUT A;  3GIS X;  3NT1 A;  4BXS A;  4TGF A;  1U8C B;  3QCW A;  2UWP B;  1MQ5 L;  4BDX A;  3SOB B;  1MOX C;  1IGX A;  5L2Z L;  1P9J A;  3HS5 A;  1LMM A;  3ZYI B;  5L2Y L;  2YGO A;  1X7A L;  1FE2 A;  3Q3K B;  1URK A;  3Q7D A;  4Z0K B;  1A3P A;  2CJI B;  3BPS E;  4X8V L;  1G1T A;  1YO8 A;  2XC5 L;  2VWL L;  4BTU A;  2ADX A;  3BT1 A;  2D1J B;  3LIW B;  4NG9 L;  1EPI A;  2KV4 A;  4D0E A;  2BQ7 A;  1KSN B;  2MHP A;  2FLG A;  1FSB A;  2F9B L;  4ZAE B;  2VVC K;  1LPG A;  3F1S B;  3V64 C;  3ENS A;  1FJS L;  1CCF A;  4RRX A;  2J38 B;  1ATB A;  2TGF A;  1YUK B;  1XKA L;  5L30 L;  4ISH L;  3N8X A;  1O5D L;  1ATD A;  5CKQ A;  4A7I A;  2P3T A;  1LQD A;  2P3F L;  1NQL B;  1LMJ A;  3TK5 B;  2P16 L;  1G2M B;  3KQC L;  1FF7 A;  1G2L B;  1W8B L;  3IIT B;  3S6X A;  6COX A;  1EPJ A;  2WPI E;  2VVV L;  1CEJ A;  4AQT A;  4O02 B;  2VJ3 A;  1DQB A;  1EPH A;  2K2S B;  4NGA L;  1FAX L;  2P93 L;  1LPK A;  5IKR A;  3KQB L;  3HO5 A;  3LN0 A;  1NFW B;  4ZXX L;  2W2O E;  3RR3 A;  1P0S L;  1COU A;  1IP0 A;  1IVO C;  4CUE A;  1Z6E L;  2Y80 B;  1F7E A;  4RRY A;  4CSY A;  1LPZ A;  3PGH A;  1KLO A;  4BTT A;  2BOU A;  1K36 A;  1UZJ A;  3HO4 A;  1CVU A;  2VH0 B;  3TBD A;  3P5B L;  4JYV L;  4M11 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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