2XBWL

Factor xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor
Total Genus 10
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
50
structure length
50
Chain Sequence
CSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
source organism Homo sapiens
publication title Discovery of a Factor Xa Inhibitor (3R,4R)-1-(2,2-Difluoro-Ethyl)-Pyrrolidine-3,4-Dicarboxylic Acid 3-[(5-Chloro-Pyridin-2-Yl)-Amide] 4-{[2-Fluoro-4-(2-Oxo-2H-Pyridin-1-Yl)-Phenyl]-Amide} as a Clinical Candidate.
pubmed doi rcsb
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 10
structure length 50
sequence length 50
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2010-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2xbwL00
2FD6A 1W7XL 1FSBA 1Z6CA 1EPHA 5JB9E 2VVCK 1EZQB 2WYJB 4M11A 4Z6AL 1J9CL 1CQEA 3LIWB 4ZH8B 5IKTA 4O1ZA 1C5MF 5CKNA 2RHPA 2K2TA 2VH0B 1YO8A 2BQ6A 4D0EA 3SOQA 1IQML 4BTTA 5E8DA 1UZQA 5JVZA 3U73A 2FLBL 3TZIA 4ZHAB 1EAIC 1HX2A 1I0UA 1UZJA 1TOZA 4JYUL 3N8YB 3H5CB 4BXSA 1NFXB 1CVWL 2AYLA 5JB8E 4G1MB 4MMYB 2K2SB 3N8XA 1P9JA 4X8TL 3V64C 1IQIL 2EI8B 1U67A 3CS7L 3LTFB 1EPJA 1EQHA 2H9EL 2W2PE 4MMZB 1JL9A 1K36A 1ATAA 4E1GA 1IQLL 2XBVL 1A3PA 4YZUB 2XBYL 3POYA 4ZAEB 3MQEA 3BPSE 2MGPA 1L3YA 3NTBA 1FAXL 2ADXA 1MOXC 1LMJA 2BZ6L 3ASIA 3LAQA 3LC5B 1F7MA 1EQGA 2P28B 2WFXB 3Q7DA 1X7AL 1UZPA 2UWOB 2P3UA 1OB1C 5CKQA 4LMFA 2PUQL 2EI6B 1U8CB 3HO4A 3FBYA 2J95B 3HO5A 3IITB 3M36L 4AQTA 3V65B 1ADXA 5F19A 1EPGA 5CISA 2Y5GL 2KB9A 1FE2A 2J94B 2BQWA 1IQGL 2P95L 1N7DA 4NG9L 2M74A 1EPIA 1F0RB 2MHPA 2W2NE 2Y7ZB 3R05A 4Y7AB 1IGXA 3N8WA 3SOBB 1IQKL 2GD4A 2WYGB 3QCWA 2J4IB 2WFTA 1IOXA 4RS0A 1KSNB 3NJPC 1PTHA 4X8UL 3F1SB 2WPKE 3M37L 1NFUB 4TGFA 1TLEA 2W2ME 3GISX 3QMOA 3FCSB 2P94L 2W26B 2JKHL 2I9AA 3NTGA 5L30L 4M10A 2W3KB 2Y5FL 2BQ7A 3BT1A 1YGCL 4Y71B 1NT0A 1IP0A 3KCGL 2B7DL 2PR3B 4COXA 2RA0L 1HAFA 1PRHA 1IOEL 5JBBE 2BOUA 1LPKA 6COXA 2Y7XB 4C16A 3KQDL 3IJEB 3N8YA 1DDXA 3RR3A 1G2LB 4Z0KB 4BTUA 3SOVA 4YT6L 1NFYB 2F9BL 1GK5A 2DDUA 1M1XB 2BO2A 3TBDA 3BT2A 1KLJL 3LN1A 4JZEL 1F7EA 1YUFA 2W3IB 3HS6A 1JV2B 1Q4GA 4Y79B 2W2OE 2FLGA 2PHBB 3HPTA 1DQBA 5JBCE 1YUGA 1FF7A 4XLWA 2NPRA 2XBXL 4RRWA 2MGRA 1FJSL 2W2QE 1COUA 2WPJE 1IQHL 2D1JB 5L2YL 5KIRA 1DVAL 2XC4L 1BF9A 2VH6B 1EBVA 4CUDA 3KQCL 1F0SB 2P3FL 1KLIL 5CKMA 4BTIA 5I46L 4Z0LA 1O5DL 1MQ6L 2VVUL 1XFEA 2Y81B 1ATDA 5IKVA 4RRXA 1TPGA 2W86A 1KLOA 2VJ3A 4OTJA 3F6UL 2XBWL 2Y5HL 3ZYGA 2BOXA 5IKRA 2P3TA 1CCFA 1AUTL 1HJ7A 1IQJL 1G2MB 1KIGL 1FAKL 3GCWE 3ENSA 4CSYA 5FDQA 3SW2A 1ATEA 1QFKL 4NGAL 2FLRL 4OTYA 1LQDA 2BMGA 1WHFA 2Y38A 1L5GB 3KQEL 5F1AA 2VWMK 5L2ZL 3TK6B 1ATBA 5EGMB 3FFGL 2OYEP 1HREA 2P3FN 3K9XA 4X8VL 3QH0A 1G1TA 3MDLA 5IKQA 4BXWA 3CENL 1IJQA 2P93L 4MMXB 3EGFA 2BOHA 3KRKA 4CUEA 1WU1B 1B9WA 1PXXA 1HZ8A 1LPGA 4JZDL 1EMOA 2I9BA 1YUKB 1PGEA 1CX2A 2J2UB 3KQBL 4BDXA 2WPHE 1APQA 1CCVA 2TGFA 4X8SL 4PH9A 3KK6A 1DX5I 1NZIA 2VWNL 1IQFL 3N8ZA 1K37A 4A7IA 3CA7A 1WHEA 2VVVL 1UZKA 4Y7BB 4RRYA 2Y82B 3TK5B 2WG4B 5KN5C 1NFWB 1HT5A 1PFXL 1HRFA 3P5BL 4LORA 2FZZL 3HS7A 1RFNB 3ELAL 3CFWA 3LTGD 4Y6DB 1SZBA 3GCXE 3HS5A 5K0HB 5JW1A 1Z6EL 4O02B 4ZXYL 4JYVL 2XC5L 3HO3A 1NPEB 3KL6B 1URKA 1LPZA 1HCGB 2Y80B 1ZAQA 3OLUA 4XBMA 1XKAL 2YGOA 4CUFA 3NT1A 1G1RA 4ZXXL 1JBUL 1HT8A 2OYUP 2YGPA 4Y76B 4BDWA 2CJIB 3ZYJB 1IGZA 2P16L 2VWLL 1IQEL 2WPME 1CVUA 2WG3C 4RRZA 1N1IA 1NQLB 1P0SL 4YT7L 3C9AC 1CEJA 2VWOL 3LC3B 2P26A 1XKBA 4D90A 1IQNL 2WPLE 1DIYA 1EMNA 3OLTA 3DEMA 1HAEA 2G00L 5COXA 4D0FA 4NA9L 2UWLB 5JVYA 2Q1JB 2EI7B 2KL7A 1G1QA 4FM5A 2BOKL 4JZFL 2XC0L 1EGFA 1FFMA 1IVOC 4RUTA 3N8WB 4ISHL 4XL1A 1G1SA 3TH3L 3TGFA 3PGHA 3U7UG 1W8BL 1XDTR 2KV4A 3Q3KB 3ZYIB 4ISIL 3LN0A 2RNLA 1APOA 1MQ5L 2WPIE 3N8VA 5JBAE 2J34B 2J38B 1V3XB 2UWPB
chains in the Genus database with same CATH superfamily
2FD6A 1W7XL 1FSBA 1Z6CA 1EPHA 5JB9E 2VVCK 1EZQB 2WYJB 4M11A 1LMMA 4Z6AL 1J9CL 1V1HA 1CQEA 3LIWB 4ZH8B 5IKTA 4O1ZA 1C5MF 5CKNA 2RHPA 2K2TA 2VH0B 1YO8A 2BQ6A 4D0EA 3SOQA 1IQML 4BTTA 2HORA 5E8DA 1UZQA 5JVZA 3U73A 2FLBL 3TZIA 4ZHAB 1EAIC 1HX2A 1I0UA 1UZJA 1TOZA 4JYUL 3N8YB 3H5CB 4BXSA 1NFXB 1CVWL 2AYLA 5JB8E 4G1MB 4MMYB 2K2SB 3N8XA 1P9JA 1V1IA 4X8TL 3V64C 1IQIL 2EI8B 1U67A 3CS7L 3LTFB 1EPJA 1EQHA 2H9EL 2W2PE 4MMZB 1JL9A 1K36A 1ATAA 4E1GA 1IQLL 2XBVL 1A3PA 4YZUB 2XBYL 3POYA 4ZAEB 3MQEA 3BPSE 2MGPA 1L3YA 3NTBA 1FAXL 2ADXA 1MOXC 1LMJA 2BZ6L 3ASIA 3LAQA 3LC5B 1F7MA 1EQGA 2P28B 2WFXB 2KNIA 3Q7DA 1X7AL 1UZPA 2UWOB 2P3UA 1OB1C 5CKQA 4LMFA 2PUQL 2EI6B 1U8CB 3HO4A 3FBYA 2J95B 3HO5A 3IITB 3M36L 4AQTA 3V65B 1ADXA 5F19A 1EPGA 5CISA 2Y5GL 2KB9A 1FE2A 2J94B 2BQWA 1IQGL 2P95L 1N7DA 4NG9L 2M74A 1EPIA 1F0RB 2MHPA 2W2NE 2Y7ZB 3R05A 4Y7AB 1IGXA 2JJLA 3N8WA 3SOBB 1IQKL 2GD4A 2WYGB 3QCWA 2J4IB 2WFTA 1IOXA 4RS0A 1KSNB 3NJPC 2WZPP 1PTHA 4X8UL 3F1SB 2WPKE 3M37L 2H9EC 1NFUB 4TGFA 1TLEA 2W2ME 3GISX 3QMOA 3FCSB 2P94L 2W26B 2JKHL 2I9AA 3NTGA 5L30L 4M10A 2W3KB 2Y5FL 2BQ7A 1KKEA 3BT1A 1YGCL 4Y71B 1NT0A 1IP0A 3KCGL 2B7DL 2PR3B 4COXA 2RA0L 1HAFA 1PRHA 1IOEL 5JBBE 2BOUA 1LPKA 6COXA 2BT7A 2Y7XB 4C16A 3KQDL 3IJEB 3N8YA 1DDXA 3RR3A 1G2LB 4Z0KB 4BTUA 3SOVA 4YT6L 1NFYB 2F9BL 1GK5A 2DDUA 1LK9A 1M1XB 2BO2A 3TBDA 3BT2A 1KLJL 3LN1A 4JZEL 1F7EA 1YUFA 2W3IB 4GU3A 3HS6A 1JV2B 1Q4GA 4Y79B 2W2OE 2FLGA 2PHBB 3HPTA 1DQBA 5JBCE 1YUGA 1FF7A 4XLWA 2NPRA 2XBXL 4RRWA 2MGRA 1FJSL 2W2QE 1COUA 2WPJE 1IQHL 2D1JB 5L2YL 5KIRA 1DVAL 2XC4L 1BF9A 2VH6B 1EBVA 4CUDA 3KQCL 1F0SB 2P3FL 1KLIL 5CKMA 4BTIA 5I46L 4Z0LA 1O5DL 1MQ6L 2VVUL 1XFEA 2Y81B 1ATDA 5IKVA 4RRXA 2HOXA 1TPGA 2W86A 1KLOA 2VJ3A 4OTJA 3F6UL 2XBWL 2Y5HL 3ZYGA 2BOXA 5IKRA 2P3TA 1CCFA 1AUTL 1HJ7A 1IQJL 1G2MB 1KIGL 1FAKL 3GCWE 3ENSA 4CSYA 5FDQA 3SW2A 2BT8A 1ATEA 1QFKL 4NGAL 2FLRL 4OTYA 1LQDA 2BMGA 1WHFA 2Y38A 1L5GB 3KQEL 5F1AA 2VWMK 5L2ZL 3TK6B 1ATBA 5EGMB 3FFGL 2VRSA 2OYEP 1HREA 2P3FN 1QIUA 3K9XA 4X8VL 3QH0A 1G1TA 3MDLA 5IKQA 2YGQA 4BXWA 3CENL 1IJQA 2P93L 4MMXB 3EGFA 2BOHA 3KRKA 4CUEA 1WU1B 1B9WA 1PXXA 1HZ8A 1LPGA 4JZDL 1EMOA 2I9BA 1YUKB 1PGEA 1CX2A 2J2UB 3KQBL 4BDXA 2WPHE 1APQA 1CCVA 2TGFA 4X8SL 4PH9A 3KK6A 1DX5I 1NZIA 2VWNL 1IQFL 3N8ZA 1K37A 4A7IA 3CA7A 1WHEA 2VVVL 1UZKA 4Y7BB 4RRYA 2Y82B 3TK5B 2WG4B 5KN5C 1NFWB 1HT5A 1PFXL 1HRFA 3P5BL 4LORA 2FZZL 3HS7A 1RFNB 3ELAL 3CFWA 3LTGD 4Y6DB 1SZBA 3GCXE 3HS5A 5K0HB 5JW1A 1Z6EL 4O02B 4ZXYL 4JYVL 2XC5L 3HO3A 1NPEB 3KL6B 3S6XA 1URKA 1LPZA 1HCGB 2Y80B 1ZAQA 3OLUA 4XBMA 1XKAL 2YGOA 4CUFA 3NT1A 1G1RA 4ZXXL 1JBUL 1HT8A 2OYUP 2YGPA 4Y76B 4BDWA 2CJIB 3ZYJB 1IGZA 2P16L 2VWLL 1IQEL 2WPME 1CVUA 2WG3C 4RRZA 1N1IA 1NQLB 1P0SL 4YT7L 3C9AC 1CEJA 2VWOL 3LC3B 2P26A 1XKBA 4D90A 1IQNL 2WPLE 1DIYA 1EMNA 3OLTA 3DEMA 1HAEA 4GU4A 2G00L 5COXA 4D0FA 4NA9L 2UWLB 5JVYA 4A94C 2Q1JB 2EI7B 2KL7A 1G1QA 4FM5A 2BOKL 4JZFL 2XC0L 1EGFA 1FFMA 1IVOC 4RUTA 3N8WB 4ISHL 4XL1A 1G1SA 2BSFA 3TH3L 3TGFA 3PGHA 3U7UG 1W8BL 1XDTR 2KV4A 3Q3KB 3ZYIB 4ISIL 3LN0A 2RNLA 1APOA 1MQ5L 2WPIE 3N8VA 5JBAE 2J34B 2J38B 1V3XB 2UWPB
chains in the Genus database with same CATH topology
2FD6A 1W7XL 1FSBA 1Z6CA 1EPHA 5JB9E 2VVCK 1EZQB 2WYJB 4M11A 1LMMA 4Z6AL 1J9CL 1CQEA 3LIWB 4ZH8B 5IKTA 4O1ZA 1C5MF 5CKNA 2RHPA 2K2TA 2VH0B 1YO8A 2BQ6A 4D0EA 3SOQA 1IQML 4BTTA 5E8DA 1UZQA 5JVZA 3U73A 2FLBL 3TZIA 4ZHAB 1EAIC 1HX2A 1I0UA 1UZJA 1TOZA 4JYUL 3N8YB 3H5CB 4BXSA 1NFXB 1CVWL 2AYLA 5JB8E 4G1MB 4MMYB 2K2SB 3N8XA 1P9JA 4X8TL 3V64C 1IQIL 2EI8B 1U67A 3CS7L 3LTFB 1EPJA 1EQHA 2H9EL 2W2PE 4MMZB 1JL9A 1K36A 1ATAA 4E1GA 1IQLL 2XBVL 1A3PA 4YZUB 2XBYL 3POYA 4ZAEB 3MQEA 3BPSE 2MGPA 1L3YA 3NTBA 1FAXL 2ADXA 1MOXC 1LMJA 2BZ6L 3ASIA 3LAQA 3LC5B 1F7MA 1EQGA 2P28B 2WFXB 2KNIA 3Q7DA 1X7AL 1UZPA 2UWOB 2P3UA 1OB1C 5CKQA 4LMFA 2PUQL 2EI6B 1U8CB 3HO4A 3FBYA 2J95B 3HO5A 3IITB 3M36L 4AQTA 3V65B 1ADXA 5F19A 1EPGA 5CISA 2Y5GL 2KB9A 1FE2A 2J94B 2BQWA 1IQGL 2P95L 1N7DA 4NG9L 2M74A 1EPIA 1F0RB 2MHPA 2W2NE 2Y7ZB 3R05A 4Y7AB 1IGXA 3N8WA 3SOBB 1IQKL 2GD4A 2WYGB 3QCWA 2J4IB 2WFTA 1IOXA 4RS0A 1KSNB 3NJPC 2WZPP 1PTHA 4X8UL 3F1SB 2WPKE 3M37L 2H9EC 1NFUB 4TGFA 1TLEA 2W2ME 3GISX 3QMOA 3FCSB 2P94L 2W26B 2JKHL 2I9AA 3NTGA 5L30L 4M10A 2W3KB 2Y5FL 2BQ7A 3BT1A 1YGCL 4Y71B 1NT0A 1IP0A 3KCGL 2B7DL 2PR3B 4COXA 2RA0L 1HAFA 1PRHA 1IOEL 5JBBE 2BOUA 1LPKA 6COXA 2Y7XB 4C16A 3KQDL 3IJEB 3N8YA 1DDXA 3RR3A 1G2LB 4Z0KB 4BTUA 3SOVA 4YT6L 1NFYB 2F9BL 1GK5A 2DDUA 1M1XB 2BO2A 3TBDA 3BT2A 1KLJL 3LN1A 4JZEL 1F7EA 1YUFA 2W3IB 3HS6A 1JV2B 1Q4GA 4Y79B 2W2OE 2FLGA 2PHBB 3HPTA 1DQBA 5JBCE 1YUGA 1FF7A 4XLWA 2NPRA 2XBXL 4RRWA 2MGRA 1FJSL 2W2QE 1COUA 2WPJE 1IQHL 2D1JB 5L2YL 5KIRA 1DVAL 2XC4L 1BF9A 2VH6B 1EBVA 4CUDA 3KQCL 1F0SB 2P3FL 1KLIL 5CKMA 4BTIA 5I46L 4Z0LA 1O5DL 1MQ6L 2VVUL 1XFEA 2Y81B 1ATDA 5IKVA 4RRXA 1TPGA 2W86A 1KLOA 2VJ3A 4OTJA 3F6UL 2XBWL 2Y5HL 3ZYGA 2BOXA 5IKRA 2P3TA 1CCFA 1AUTL 1HJ7A 1IQJL 1G2MB 1KIGL 1FAKL 3GCWE 3ENSA 4CSYA 5FDQA 3SW2A 1ATEA 1QFKL 4NGAL 2FLRL 4OTYA 1LQDA 2BMGA 1WHFA 2Y38A 1L5GB 3KQEL 5F1AA 2VWMK 5L2ZL 3TK6B 1ATBA 5EGMB 3FFGL 2OYEP 1HREA 2P3FN 3K9XA 4X8VL 3QH0A 1G1TA 3MDLA 5IKQA 2YGQA 4BXWA 3CENL 1IJQA 2P93L 4MMXB 3EGFA 2BOHA 3KRKA 4CUEA 1WU1B 1B9WA 1PXXA 1HZ8A 1LPGA 4JZDL 1EMOA 2I9BA 1YUKB 1PGEA 1CX2A 2J2UB 3KQBL 4BDXA 2WPHE 1APQA 1CCVA 2TGFA 4X8SL 4PH9A 3KK6A 1DX5I 1NZIA 2VWNL 1IQFL 3N8ZA 1K37A 4A7IA 3CA7A 1WHEA 2VVVL 1UZKA 4Y7BB 4RRYA 2Y82B 3TK5B 2WG4B 5KN5C 1NFWB 1HT5A 1PFXL 1HRFA 3P5BL 4LORA 2FZZL 3HS7A 1RFNB 3ELAL 3CFWA 3LTGD 4Y6DB 1SZBA 3GCXE 3HS5A 5K0HB 5JW1A 1Z6EL 4O02B 4ZXYL 4JYVL 2XC5L 3HO3A 1NPEB 3KL6B 3S6XA 1URKA 1LPZA 1HCGB 2Y80B 1ZAQA 3OLUA 4XBMA 1XKAL 2YGOA 4CUFA 3NT1A 1G1RA 4ZXXL 1JBUL 1HT8A 2OYUP 2YGPA 4Y76B 4BDWA 2CJIB 3ZYJB 1IGZA 2P16L 2VWLL 1IQEL 2WPME 1CVUA 2WG3C 4RRZA 1N1IA 1NQLB 1P0SL 4YT7L 3C9AC 1CEJA 2VWOL 3LC3B 2P26A 1XKBA 4D90A 1IQNL 2WPLE 1DIYA 1EMNA 3OLTA 3DEMA 1HAEA 2G00L 5COXA 4D0FA 4NA9L 2UWLB 5JVYA 4A94C 2Q1JB 2EI7B 2KL7A 1G1QA 4FM5A 2BOKL 4JZFL 2XC0L 1EGFA 1FFMA 1IVOC 4RUTA 3N8WB 4ISHL 4XL1A 1G1SA 3TH3L 3TGFA 3PGHA 3U7UG 1W8BL 1XDTR 2KV4A 3Q3KB 3ZYIB 4ISIL 3LN0A 2RNLA 1APOA 1MQ5L 2WPIE 3N8VA 5JBAE 2J34B 2J38B 1V3XB 2UWPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FD6 A;  1W7X L;  1FSB A;  1Z6C A;  1EPH A;  5JB9 E;  2VVC K;  1EZQ B;  2WYJ B;  4M11 A;  4Z6A L;  1J9C L;  1CQE A;  3LIW B;  4ZH8 B;  5IKT A;  4O1Z A;  1C5M F;  5CKN A;  2RHP A;  2K2T A;  2VH0 B;  1YO8 A;  2BQ6 A;  4D0E A;  3SOQ A;  1IQM L;  4BTT A;  5E8D A;  1UZQ A;  5JVZ A;  3U73 A;  2FLB L;  3TZI A;  4ZHA B;  1EAI C;  1HX2 A;  1I0U A;  1UZJ A;  1TOZ A;  4JYU L;  3N8Y B;  3H5C B;  4BXS A;  1NFX B;  1CVW L;  2AYL A;  5JB8 E;  4G1M B;  4MMY B;  2K2S B;  3N8X A;  1P9J A;  4X8T L;  3V64 C;  1IQI L;  2EI8 B;  1U67 A;  3CS7 L;  3LTF B;  1EPJ A;  1EQH A;  2H9E L;  2W2P E;  4MMZ B;  1JL9 A;  1K36 A;  1ATA A;  4E1G A;  1IQL L;  2XBV L;  1A3P A;  4YZU B;  2XBY L;  3POY A;  4ZAE B;  3MQE A;  3BPS E;  2MGP A;  1L3Y A;  3NTB A;  1FAX L;  2ADX A;  1MOX C;  1LMJ A;  2BZ6 L;  3ASI A;  3LAQ A;  3LC5 B;  1F7M A;  1EQG A;  2P28 B;  2WFX B;  3Q7D A;  1X7A L;  1UZP A;  2UWO B;  2P3U A;  1OB1 C;  5CKQ A;  4LMF A;  2PUQ L;  2EI6 B;  1U8C B;  3HO4 A;  3FBY A;  2J95 B;  3HO5 A;  3IIT B;  3M36 L;  4AQT A;  3V65 B;  1ADX A;  5F19 A;  1EPG A;  5CIS A;  2Y5G L;  2KB9 A;  1FE2 A;  2J94 B;  2BQW A;  1IQG L;  2P95 L;  1N7D A;  4NG9 L;  2M74 A;  1EPI A;  1F0R B;  2MHP A;  2W2N E;  2Y7Z B;  3R05 A;  4Y7A B;  1IGX A;  3N8W A;  3SOB B;  1IQK L;  2GD4 A;  2WYG B;  3QCW A;  2J4I B;  2WFT A;  1IOX A;  4RS0 A;  1KSN B;  3NJP C;  1PTH A;  4X8U L;  3F1S B;  2WPK E;  3M37 L;  1NFU B;  4TGF A;  1TLE A;  2W2M E;  3GIS X;  3QMO A;  3FCS B;  2P94 L;  2W26 B;  2JKH L;  2I9A A;  3NTG A;  5L30 L;  4M10 A;  2W3K B;  2Y5F L;  2BQ7 A;  3BT1 A;  1YGC L;  4Y71 B;  1NT0 A;  1IP0 A;  3KCG L;  2B7D L;  2PR3 B;  4COX A;  2RA0 L;  1HAF A;  1PRH A;  1IOE L;  5JBB E;  2BOU A;  1LPK A;  6COX A;  2Y7X B;  4C16 A;  3KQD L;  3IJE B;  3N8Y A;  1DDX A;  3RR3 A;  1G2L B;  4Z0K B;  4BTU A;  3SOV A;  4YT6 L;  1NFY B;  2F9B L;  1GK5 A;  2DDU A;  1M1X B;  2BO2 A;  3TBD A;  3BT2 A;  1KLJ L;  3LN1 A;  4JZE L;  1F7E A;  1YUF A;  2W3I B;  3HS6 A;  1JV2 B;  1Q4G A;  4Y79 B;  2W2O E;  2FLG A;  2PHB B;  3HPT A;  1DQB A;  5JBC E;  1YUG A;  1FF7 A;  4XLW A;  2NPR A;  2XBX L;  4RRW A;  2MGR A;  1FJS L;  2W2Q E;  1COU A;  2WPJ E;  1IQH L;  2D1J B;  5L2Y L;  5KIR A;  1DVA L;  2XC4 L;  1BF9 A;  2VH6 B;  1EBV A;  4CUD A;  3KQC L;  1F0S B;  2P3F L;  1KLI L;  5CKM A;  4BTI A;  5I46 L;  4Z0L A;  1O5D L;  1MQ6 L;  2VVU L;  1XFE A;  2Y81 B;  1ATD A;  5IKV A;  4RRX A;  1TPG A;  2W86 A;  1KLO A;  2VJ3 A;  4OTJ A;  3F6U L;  2XBW L;  2Y5H L;  3ZYG A;  2BOX A;  5IKR A;  2P3T A;  1CCF A;  1AUT L;  1HJ7 A;  1IQJ L;  1G2M B;  1KIG L;  1FAK L;  3GCW E;  3ENS A;  4CSY A;  5FDQ A;  3SW2 A;  1ATE A;  1QFK L;  4NGA L;  2FLR L;  4OTY A;  1LQD A;  2BMG A;  1WHF A;  2Y38 A;  1L5G B;  3KQE L;  5F1A A;  2VWM K;  5L2Z L;  3TK6 B;  1ATB A;  5EGM B;  3FFG L;  2OYE P;  1HRE A;  2P3F N;  3K9X A;  4X8V L;  3QH0 A;  1G1T A;  3MDL A;  5IKQ A;  4BXW A;  3CEN L;  1IJQ A;  2P93 L;  4MMX B;  3EGF A;  2BOH A;  3KRK A;  4CUE A;  1WU1 B;  1B9W A;  1PXX A;  1HZ8 A;  1LPG A;  4JZD L;  1EMO A;  2I9B A;  1YUK B;  1PGE A;  1CX2 A;  2J2U B;  3KQB L;  4BDX A;  2WPH E;  1APQ A;  1CCV A;  2TGF A;  4X8S L;  4PH9 A;  3KK6 A;  1DX5 I;  1NZI A;  2VWN L;  1IQF L;  3N8Z A;  1K37 A;  4A7I A;  3CA7 A;  1WHE A;  2VVV L;  1UZK A;  4Y7B B;  4RRY A;  2Y82 B;  3TK5 B;  2WG4 B;  5KN5 C;  1NFW B;  1HT5 A;  1PFX L;  1HRF A;  3P5B L;  4LOR A;  2FZZ L;  3HS7 A;  1RFN B;  3ELA L;  3CFW A;  3LTG D;  4Y6D B;  1SZB A;  3GCX E;  3HS5 A;  5K0H B;  5JW1 A;  1Z6E L;  4O02 B;  4ZXY L;  4JYV L;  2XC5 L;  3HO3 A;  1NPE B;  3KL6 B;  1URK A;  1LPZ A;  1HCG B;  2Y80 B;  1ZAQ A;  3OLU A;  4XBM A;  1XKA L;  2YGO A;  4CUF A;  3NT1 A;  1G1R A;  4ZXX L;  1JBU L;  1HT8 A;  2OYU P;  2YGP A;  4Y76 B;  4BDW A;  2CJI B;  3ZYJ B;  1IGZ A;  2P16 L;  2VWL L;  1IQE L;  2WPM E;  1CVU A;  2WG3 C;  4RRZ A;  1N1I A;  1NQL B;  1P0S L;  4YT7 L;  3C9A C;  1CEJ A;  2VWO L;  3LC3 B;  2P26 A;  1XKB A;  4D90 A;  1IQN L;  2WPL E;  1DIY A;  1EMN A;  3OLT A;  3DEM A;  1HAE A;  2G00 L;  5COX A;  4D0F A;  4NA9 L;  2UWL B;  5JVY A;  2Q1J B;  2EI7 B;  2KL7 A;  1G1Q A;  4FM5 A;  2BOK L;  4JZF L;  2XC0 L;  1EGF A;  1FFM A;  1IVO C;  4RUT A;  3N8W B;  4ISH L;  4XL1 A;  1G1S A;  3TH3 L;  3TGF A;  3PGH A;  3U7U G;  1W8B L;  1XDT R;  2KV4 A;  3Q3K B;  3ZYI B;  4ISI L;  3LN0 A;  2RNL A;  1APO A;  1MQ5 L;  2WPI E;  3N8V A;  5JBA E;  2J34 B;  2J38 B;  1V3X B;  2UWP B; 
#chains in the Genus database with same CATH topology
 2FD6 A;  1W7X L;  1FSB A;  1Z6C A;  1EPH A;  5JB9 E;  2VVC K;  1EZQ B;  2WYJ B;  4M11 A;  1LMM A;  4Z6A L;  1J9C L;  1V1H A;  1CQE A;  3LIW B;  4ZH8 B;  5IKT A;  4O1Z A;  1C5M F;  5CKN A;  2RHP A;  2K2T A;  2VH0 B;  1YO8 A;  2BQ6 A;  4D0E A;  3SOQ A;  1IQM L;  4BTT A;  2HOR A;  5E8D A;  1UZQ A;  5JVZ A;  3U73 A;  2FLB L;  3TZI A;  4ZHA B;  1EAI C;  1HX2 A;  1I0U A;  1UZJ A;  1TOZ A;  4JYU L;  3N8Y B;  3H5C B;  4BXS A;  1NFX B;  1CVW L;  2AYL A;  5JB8 E;  4G1M B;  4MMY B;  2K2S B;  3N8X A;  1P9J A;  1V1I A;  4X8T L;  3V64 C;  1IQI L;  2EI8 B;  1U67 A;  3CS7 L;  3LTF B;  1EPJ A;  1EQH A;  2H9E L;  2W2P E;  4MMZ B;  1JL9 A;  1K36 A;  1ATA A;  4E1G A;  1IQL L;  2XBV L;  1A3P A;  4YZU B;  2XBY L;  3POY A;  4ZAE B;  3MQE A;  3BPS E;  2MGP A;  1L3Y A;  3NTB A;  1FAX L;  2ADX A;  1MOX C;  1LMJ A;  2BZ6 L;  3ASI A;  3LAQ A;  3LC5 B;  1F7M A;  1EQG A;  2P28 B;  2WFX B;  2KNI A;  3Q7D A;  1X7A L;  1UZP A;  2UWO B;  2P3U A;  1OB1 C;  5CKQ A;  4LMF A;  2PUQ L;  2EI6 B;  1U8C B;  3HO4 A;  3FBY A;  2J95 B;  3HO5 A;  3IIT B;  3M36 L;  4AQT A;  3V65 B;  1ADX A;  5F19 A;  1EPG A;  5CIS A;  2Y5G L;  2KB9 A;  1FE2 A;  2J94 B;  2BQW A;  1IQG L;  2P95 L;  1N7D A;  4NG9 L;  2M74 A;  1EPI A;  1F0R B;  2MHP A;  2W2N E;  2Y7Z B;  3R05 A;  4Y7A B;  1IGX A;  2JJL A;  3N8W A;  3SOB B;  1IQK L;  2GD4 A;  2WYG B;  3QCW A;  2J4I B;  2WFT A;  1IOX A;  4RS0 A;  1KSN B;  3NJP C;  2WZP P;  1PTH A;  4X8U L;  3F1S B;  2WPK E;  3M37 L;  2H9E C;  1NFU B;  4TGF A;  1TLE A;  2W2M E;  3GIS X;  3QMO A;  3FCS B;  2P94 L;  2W26 B;  2JKH L;  2I9A A;  3NTG A;  5L30 L;  4M10 A;  2W3K B;  2Y5F L;  2BQ7 A;  1KKE A;  3BT1 A;  1YGC L;  4Y71 B;  1NT0 A;  1IP0 A;  3KCG L;  2B7D L;  2PR3 B;  4COX A;  2RA0 L;  1HAF A;  1PRH A;  1IOE L;  5JBB E;  2BOU A;  1LPK A;  6COX A;  2BT7 A;  2Y7X B;  4C16 A;  3KQD L;  3IJE B;  3N8Y A;  1DDX A;  3RR3 A;  1G2L B;  4Z0K B;  4BTU A;  3SOV A;  4YT6 L;  1NFY B;  2F9B L;  1GK5 A;  2DDU A;  1LK9 A;  1M1X B;  2BO2 A;  3TBD A;  3BT2 A;  1KLJ L;  3LN1 A;  4JZE L;  1F7E A;  1YUF A;  2W3I B;  4GU3 A;  3HS6 A;  1JV2 B;  1Q4G A;  4Y79 B;  2W2O E;  2FLG A;  2PHB B;  3HPT A;  1DQB A;  5JBC E;  1YUG A;  1FF7 A;  4XLW A;  2NPR A;  2XBX L;  4RRW A;  2MGR A;  1FJS L;  2W2Q E;  1COU A;  2WPJ E;  1IQH L;  2D1J B;  5L2Y L;  5KIR A;  1DVA L;  2XC4 L;  1BF9 A;  2VH6 B;  1EBV A;  4CUD A;  3KQC L;  1F0S B;  2P3F L;  1KLI L;  5CKM A;  4BTI A;  5I46 L;  4Z0L A;  1O5D L;  1MQ6 L;  2VVU L;  1XFE A;  2Y81 B;  1ATD A;  5IKV A;  4RRX A;  2HOX A;  1TPG A;  2W86 A;  1KLO A;  2VJ3 A;  4OTJ A;  3F6U L;  2XBW L;  2Y5H L;  3ZYG A;  2BOX A;  5IKR A;  2P3T A;  1CCF A;  1AUT L;  1HJ7 A;  1IQJ L;  1G2M B;  1KIG L;  1FAK L;  3GCW E;  3ENS A;  4CSY A;  5FDQ A;  3SW2 A;  2BT8 A;  1ATE A;  1QFK L;  4NGA L;  2FLR L;  4OTY A;  1LQD A;  2BMG A;  1WHF A;  2Y38 A;  1L5G B;  3KQE L;  5F1A A;  2VWM K;  5L2Z L;  3TK6 B;  1ATB A;  5EGM B;  3FFG L;  2VRS A;  2OYE P;  1HRE A;  2P3F N;  1QIU A;  3K9X A;  4X8V L;  3QH0 A;  1G1T A;  3MDL A;  5IKQ A;  2YGQ A;  4BXW A;  3CEN L;  1IJQ A;  2P93 L;  4MMX B;  3EGF A;  2BOH A;  3KRK A;  4CUE A;  1WU1 B;  1B9W A;  1PXX A;  1HZ8 A;  1LPG A;  4JZD L;  1EMO A;  2I9B A;  1YUK B;  1PGE A;  1CX2 A;  2J2U B;  3KQB L;  4BDX A;  2WPH E;  1APQ A;  1CCV A;  2TGF A;  4X8S L;  4PH9 A;  3KK6 A;  1DX5 I;  1NZI A;  2VWN L;  1IQF L;  3N8Z A;  1K37 A;  4A7I A;  3CA7 A;  1WHE A;  2VVV L;  1UZK A;  4Y7B B;  4RRY A;  2Y82 B;  3TK5 B;  2WG4 B;  5KN5 C;  1NFW B;  1HT5 A;  1PFX L;  1HRF A;  3P5B L;  4LOR A;  2FZZ L;  3HS7 A;  1RFN B;  3ELA L;  3CFW A;  3LTG D;  4Y6D B;  1SZB A;  3GCX E;  3HS5 A;  5K0H B;  5JW1 A;  1Z6E L;  4O02 B;  4ZXY L;  4JYV L;  2XC5 L;  3HO3 A;  1NPE B;  3KL6 B;  3S6X A;  1URK A;  1LPZ A;  1HCG B;  2Y80 B;  1ZAQ A;  3OLU A;  4XBM A;  1XKA L;  2YGO A;  4CUF A;  3NT1 A;  1G1R A;  4ZXX L;  1JBU L;  1HT8 A;  2OYU P;  2YGP A;  4Y76 B;  4BDW A;  2CJI B;  3ZYJ B;  1IGZ A;  2P16 L;  2VWL L;  1IQE L;  2WPM E;  1CVU A;  2WG3 C;  4RRZ A;  1N1I A;  1NQL B;  1P0S L;  4YT7 L;  3C9A C;  1CEJ A;  2VWO L;  3LC3 B;  2P26 A;  1XKB A;  4D90 A;  1IQN L;  2WPL E;  1DIY A;  1EMN A;  3OLT A;  3DEM A;  1HAE A;  4GU4 A;  2G00 L;  5COX A;  4D0F A;  4NA9 L;  2UWL B;  5JVY A;  4A94 C;  2Q1J B;  2EI7 B;  2KL7 A;  1G1Q A;  4FM5 A;  2BOK L;  4JZF L;  2XC0 L;  1EGF A;  1FFM A;  1IVO C;  4RUT A;  3N8W B;  4ISH L;  4XL1 A;  1G1S A;  2BSF A;  3TH3 L;  3TGF A;  3PGH A;  3U7U G;  1W8B L;  1XDT R;  2KV4 A;  3Q3K B;  3ZYI B;  4ISI L;  3LN0 A;  2RNL A;  1APO A;  1MQ5 L;  2WPI E;  3N8V A;  5JBA E;  2J34 B;  2J38 B;  1V3X B;  2UWP B; 
#chains in the Genus database with same CATH homology
 2FD6 A;  1W7X L;  1FSB A;  1Z6C A;  1EPH A;  5JB9 E;  2VVC K;  1EZQ B;  2WYJ B;  4M11 A;  1LMM A;  4Z6A L;  1J9C L;  1CQE A;  3LIW B;  4ZH8 B;  5IKT A;  4O1Z A;  1C5M F;  5CKN A;  2RHP A;  2K2T A;  2VH0 B;  1YO8 A;  2BQ6 A;  4D0E A;  3SOQ A;  1IQM L;  4BTT A;  5E8D A;  1UZQ A;  5JVZ A;  3U73 A;  2FLB L;  3TZI A;  4ZHA B;  1EAI C;  1HX2 A;  1I0U A;  1UZJ A;  1TOZ A;  4JYU L;  3N8Y B;  3H5C B;  4BXS A;  1NFX B;  1CVW L;  2AYL A;  5JB8 E;  4G1M B;  4MMY B;  2K2S B;  3N8X A;  1P9J A;  4X8T L;  3V64 C;  1IQI L;  2EI8 B;  1U67 A;  3CS7 L;  3LTF B;  1EPJ A;  1EQH A;  2H9E L;  2W2P E;  4MMZ B;  1JL9 A;  1K36 A;  1ATA A;  4E1G A;  1IQL L;  2XBV L;  1A3P A;  4YZU B;  2XBY L;  3POY A;  4ZAE B;  3MQE A;  3BPS E;  2MGP A;  1L3Y A;  3NTB A;  1FAX L;  2ADX A;  1MOX C;  1LMJ A;  2BZ6 L;  3ASI A;  3LAQ A;  3LC5 B;  1F7M A;  1EQG A;  2P28 B;  2WFX B;  2KNI A;  3Q7D A;  1X7A L;  1UZP A;  2UWO B;  2P3U A;  1OB1 C;  5CKQ A;  4LMF A;  2PUQ L;  2EI6 B;  1U8C B;  3HO4 A;  3FBY A;  2J95 B;  3HO5 A;  3IIT B;  3M36 L;  4AQT A;  3V65 B;  1ADX A;  5F19 A;  1EPG A;  5CIS A;  2Y5G L;  2KB9 A;  1FE2 A;  2J94 B;  2BQW A;  1IQG L;  2P95 L;  1N7D A;  4NG9 L;  2M74 A;  1EPI A;  1F0R B;  2MHP A;  2W2N E;  2Y7Z B;  3R05 A;  4Y7A B;  1IGX A;  3N8W A;  3SOB B;  1IQK L;  2GD4 A;  2WYG B;  3QCW A;  2J4I B;  2WFT A;  1IOX A;  4RS0 A;  1KSN B;  3NJP C;  2WZP P;  1PTH A;  4X8U L;  3F1S B;  2WPK E;  3M37 L;  2H9E C;  1NFU B;  4TGF A;  1TLE A;  2W2M E;  3GIS X;  3QMO A;  3FCS B;  2P94 L;  2W26 B;  2JKH L;  2I9A A;  3NTG A;  5L30 L;  4M10 A;  2W3K B;  2Y5F L;  2BQ7 A;  3BT1 A;  1YGC L;  4Y71 B;  1NT0 A;  1IP0 A;  3KCG L;  2B7D L;  2PR3 B;  4COX A;  2RA0 L;  1HAF A;  1PRH A;  1IOE L;  5JBB E;  2BOU A;  1LPK A;  6COX A;  2Y7X B;  4C16 A;  3KQD L;  3IJE B;  3N8Y A;  1DDX A;  3RR3 A;  1G2L B;  4Z0K B;  4BTU A;  3SOV A;  4YT6 L;  1NFY B;  2F9B L;  1GK5 A;  2DDU A;  1M1X B;  2BO2 A;  3TBD A;  3BT2 A;  1KLJ L;  3LN1 A;  4JZE L;  1F7E A;  1YUF A;  2W3I B;  3HS6 A;  1JV2 B;  1Q4G A;  4Y79 B;  2W2O E;  2FLG A;  2PHB B;  3HPT A;  1DQB A;  5JBC E;  1YUG A;  1FF7 A;  4XLW A;  2NPR A;  2XBX L;  4RRW A;  2MGR A;  1FJS L;  2W2Q E;  1COU A;  2WPJ E;  1IQH L;  2D1J B;  5L2Y L;  5KIR A;  1DVA L;  2XC4 L;  1BF9 A;  2VH6 B;  1EBV A;  4CUD A;  3KQC L;  1F0S B;  2P3F L;  1KLI L;  5CKM A;  4BTI A;  5I46 L;  4Z0L A;  1O5D L;  1MQ6 L;  2VVU L;  1XFE A;  2Y81 B;  1ATD A;  5IKV A;  4RRX A;  1TPG A;  2W86 A;  1KLO A;  2VJ3 A;  4OTJ A;  3F6U L;  2XBW L;  2Y5H L;  3ZYG A;  2BOX A;  5IKR A;  2P3T A;  1CCF A;  1AUT L;  1HJ7 A;  1IQJ L;  1G2M B;  1KIG L;  1FAK L;  3GCW E;  3ENS A;  4CSY A;  5FDQ A;  3SW2 A;  1ATE A;  1QFK L;  4NGA L;  2FLR L;  4OTY A;  1LQD A;  2BMG A;  1WHF A;  2Y38 A;  1L5G B;  3KQE L;  5F1A A;  2VWM K;  5L2Z L;  3TK6 B;  1ATB A;  5EGM B;  3FFG L;  2OYE P;  1HRE A;  2P3F N;  3K9X A;  4X8V L;  3QH0 A;  1G1T A;  3MDL A;  5IKQ A;  2YGQ A;  4BXW A;  3CEN L;  1IJQ A;  2P93 L;  4MMX B;  3EGF A;  2BOH A;  3KRK A;  4CUE A;  1WU1 B;  1B9W A;  1PXX A;  1HZ8 A;  1LPG A;  4JZD L;  1EMO A;  2I9B A;  1YUK B;  1PGE A;  1CX2 A;  2J2U B;  3KQB L;  4BDX A;  2WPH E;  1APQ A;  1CCV A;  2TGF A;  4X8S L;  4PH9 A;  3KK6 A;  1DX5 I;  1NZI A;  2VWN L;  1IQF L;  3N8Z A;  1K37 A;  4A7I A;  3CA7 A;  1WHE A;  2VVV L;  1UZK A;  4Y7B B;  4RRY A;  2Y82 B;  3TK5 B;  2WG4 B;  5KN5 C;  1NFW B;  1HT5 A;  1PFX L;  1HRF A;  3P5B L;  4LOR A;  2FZZ L;  3HS7 A;  1RFN B;  3ELA L;  3CFW A;  3LTG D;  4Y6D B;  1SZB A;  3GCX E;  3HS5 A;  5K0H B;  5JW1 A;  1Z6E L;  4O02 B;  4ZXY L;  4JYV L;  2XC5 L;  3HO3 A;  1NPE B;  3KL6 B;  3S6X A;  1URK A;  1LPZ A;  1HCG B;  2Y80 B;  1ZAQ A;  3OLU A;  4XBM A;  1XKA L;  2YGO A;  4CUF A;  3NT1 A;  1G1R A;  4ZXX L;  1JBU L;  1HT8 A;  2OYU P;  2YGP A;  4Y76 B;  4BDW A;  2CJI B;  3ZYJ B;  1IGZ A;  2P16 L;  2VWL L;  1IQE L;  2WPM E;  1CVU A;  2WG3 C;  4RRZ A;  1N1I A;  1NQL B;  1P0S L;  4YT7 L;  3C9A C;  1CEJ A;  2VWO L;  3LC3 B;  2P26 A;  1XKB A;  4D90 A;  1IQN L;  2WPL E;  1DIY A;  1EMN A;  3OLT A;  3DEM A;  1HAE A;  2G00 L;  5COX A;  4D0F A;  4NA9 L;  2UWL B;  5JVY A;  4A94 C;  2Q1J B;  2EI7 B;  2KL7 A;  1G1Q A;  4FM5 A;  2BOK L;  4JZF L;  2XC0 L;  1EGF A;  1FFM A;  1IVO C;  4RUT A;  3N8W B;  4ISH L;  4XL1 A;  1G1S A;  3TH3 L;  3TGF A;  3PGH A;  3U7U G;  1W8B L;  1XDT R;  2KV4 A;  3Q3K B;  3ZYI B;  4ISI L;  3LN0 A;  2RNL A;  1APO A;  1MQ5 L;  2WPI E;  3N8V A;  5JBA E;  2J34 B;  2J38 B;  1V3X B;  2UWP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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