2BQWA

Crystal structure of factor xa in complex with compound 45
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold: A Study Combining Structure-Activity Relationship and X-Ray Crystallography.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords COAGULATION FACTOR X
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2005-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2bqwA00
1IQEL 4BDWA 1TPGA 2BQ6A 1ATEA 2VJ3A 1K36A 1EQHA 2KL7A 1EGFA 2FZZL 5F19A 5CKNA 1F0SB 2BMGA 1PGEA 1MQ6L 2XC4L 1EPHA 3LAQA 3N8WB 4OTYA 2BOUA 1FAXL 4CUDA 5COXA 5FDQA 2D1JB 1W8BL 1IQML 1DVAL 5CKQA 2W2ME 2VVCK 2PUQL 3HS6A 1EBVA 1G2MB 3KQDL 1Z6EL 4ZXYL 1CCFA 2EI8B 2J38B 4NA9L 2W2PE 1FFMA 1KLJL 5F1AA 2Y7XB 1G1RA 2WPLE 1UZQA 3CA7A 1X7AL 6COXA 1QFKL 2Y81B 3R05A 5KN5C 1COUA 1HZ8A 1LPGA 2Y5GL 3LN1A 1SZBA 1M1XB 1RFNB 3HO5A 3HS5A 5K0HB 1UZPA 1JV2B 1IQGL 1IQFL 3KL6B 1EPJA 1IOXA 4O1ZA 1CQEA 3QCWA 1IQIL 5JBAE 2W26B 1DQBA 1WHFA 4X8TL 4Y76B 2P94L 3IJEB 5JW1A 1ATAA 4Y71B 1EPGA 3NTGA 4E1GA 3U73A 2UWLB 1HX2A 2BOKL 2G00L 4X8UL 1XFEA 4MMYB 1W7XL 3CENL 2KB9A 4RRXA 3FCSB 1LPZA 3TGFA 4D0EA 3KCGL 4D90A 2I9AA 2M74A 2VH0B 3M37L 3ELAL 1G2LB 1UZJA 2XBWL 3EGFA 1I0UA 1ATBA 1NFXB 1P9JA 1EAIC 2BQWA 1YGCL 2ADXA 2UWPB 1IP0A 2B7DL 3GCXE 4CUFA 1LMJA 5JVYA 1L5GB 1F0RB 5CISA 3V65B 3Q7DA 1EPIA 3BT2A 2KV4A 2YGPA 1HJ7A 1XDTR 3QH0A 3NTBA 3DEMA 4TGFA 1EQGA 1NQLB 3LTFB 4Z0LA 4O02B 3SOVA 1MQ5L 1XKAL 1IQJL 1JBUL 5KIRA 2WYGB 2W2QE 1EMNA 2W3IB 5JVZA 2YGOA 3P5BL 4ZXXL 1KLOA 2PHBB 1LQDA 3CFWA 2WYJB 1IQNL 2OYUP 1F7EA 2TGFA 1V3XB 1YUKB 3NT1A 2BQ7A 4COXA 3RR3A 4M10A 4JZDL 4AQTA 2WG3C 2FLGA 3PGHA 3SOQA 1FE2A 3H5CB 3C9AC 1EMOA 2XC5L 1PFXL 2VVVL 1CCVA 1IQKL 2VWOL 2Y7ZB 4BXWA 1HT5A 1ZAQA 4MMZB 4X8SL 3N8YA 1U67A 1L3YA 2P3UA 2BO2A 2RHPA 2WPKE 5L2ZL 2J34B 3LC5B 4YZUB 3LC3B 5L30L 3K9XA 1WHEA 1NZIA 3FBYA 3N8ZA 2Q1JB 2RA0L 3N8VA 3HPTA 3N8XA 1DX5I 2BOHA 3HO4A 1B9WA 4X8VL 4D0FA 4Y7BB 3TBDA 2XBYL 2P3TA 3TZIA 1F7MA 3N8YB 3LIWB 1EZQB 2OYEP 3POYA 1BF9A 1OB1C 3F1SB 4JZFL 2EI7B 4CSYA 3V64C 4PH9A 3Q3KB 3GCWE 2P93L 5IKRA 4BTTA 2VH6B 1NPEB 4Y7AB 1ATDA 3IITB 4BXSA 1TOZA 5IKVA 2P26A 2P95L 4NGAL 4XLWA 3ASIA 4Z0KB 1C5MF 1HCGB 2JKHL 2EI6B 4Y79B 2RNLA 1PRHA 4ZAEB 4BTUA 1YUFA 2WPME 1FF7A 1KIGL 4ZHAB 2K2TA 2UWOB 1APOA 2PR3B 4NG9L 5IKTA 4RRWA 1TLEA 3KK6A 4BTIA 1CX2A 2Y38A 1CEJA 2P16L 5JBBE 1NFUB 1FJSL 2XBXL 4ZH8B 1HAEA 2VVUL 1NT0A 4XL1A 1G1SA 2GD4A 4Y6DB 5JB8E 3TH3L 1DIYA 4G1MB 1IVOC 4MMXB 2H9EL 4C16A 3GISX 2FD6A 1J9CL 1FSBA 3HS7A 2XBVL 3M36L 1O5DL 3NJPC 2W2OE 3MDLA 2NPRA 2J2UB 4OTJA 1G1QA 1IOEL 3TK6B 3KRKA 1HREA 1YO8A 1HAFA 1PTHA 1CVWL 1HRFA 1DDXA 1FAKL 1NFWB 4JYVL 1K37A 5IKQA 1G1TA 1IQHL 2BOXA 2Y82B 2VWNL 2AYLA 2J4IB 4FM5A 4JZEL 1KSNB 3ZYGA 4RRZA 1AUTL 2P3FN 1CVUA 1GK5A 4JYUL 5L2YL 4RRYA 2WPHE 2WFTA 1WU1B 4XBMA 1UZKA 5JB9E 2J95B 1HT8A 3U7UG 4M11A 3ZYIB 3KQBL 2F9BL 1IGXA 2WG4B 4RUTA 2P3FL 1IGZA 3F6UL 4BDXA 1NFYB 3SOBB 2VWMK 1APQA 2XC0L 2FLRL 2Y80B 2WFXB 3SW2A 1Z6CA 2DDUA 3ENSA 1P0SL 2P28B 3KQEL 2K2SB 3BPSE 1N7DA 4ISIL 4Z6AL 1YUGA 1JL9A 3KQCL 2J94B 2VWLL 1IQLL 2W2NE 2MHPA 4ISHL 5CKMA 2WPIE 5E8DA 1KLIL 2WPJE 1IJQA 3MQEA 5EGMB 1A3PA 3OLTA 3FFGL 2FLBL 2W3KB 1LPKA 4YT6L 1XKBA 4CUEA 2CJIB 3LTGD 4A7IA 2I9BA 3LN0A 5I46L 3BT1A 4LMFA 1N1IA 3OLUA 4LORA 3TK5B 4YT7L 5JBCE 2W86A 2Y5HL 1URKA 2Y5FL 3ZYJB 2MGRA 1MOXC 1Q4GA 3N8WA 1U8CB 2MGPA 3CS7L 2BZ6L 4RS0A 3QMOA 3HO3A 1PXXA 1ADXA
chains in the Genus database with same CATH superfamily
1IQEL 4BDWA 1TPGA 2BQ6A 1ATEA 2VJ3A 1K36A 1EQHA 2KL7A 1EGFA 2FZZL 5F19A 5CKNA 1F0SB 2BMGA 1PGEA 1MQ6L 2XC4L 1EPHA 3LAQA 3N8WB 4OTYA 2BOUA 1FAXL 4CUDA 5COXA 5FDQA 2D1JB 1V1HA 1W8BL 1IQML 1DVAL 5CKQA 2W2ME 2VVCK 2PUQL 3HS6A 1EBVA 1G2MB 3KQDL 1Z6EL 4ZXYL 1CCFA 2EI8B 2J38B 4NA9L 2W2PE 1FFMA 1KLJL 5F1AA 2Y7XB 1G1RA 2WPLE 1UZQA 3CA7A 1X7AL 6COXA 1QFKL 2Y81B 2H9EC 3R05A 5KN5C 1COUA 1HZ8A 1LPGA 2Y5GL 3LN1A 1SZBA 1M1XB 1RFNB 3HO5A 3HS5A 5K0HB 1UZPA 1JV2B 2BT8A 1IQGL 1IQFL 3KL6B 1EPJA 1IOXA 4O1ZA 1CQEA 3QCWA 1IQIL 5JBAE 2W26B 1DQBA 1WHFA 4X8TL 4Y76B 2P94L 3IJEB 5JW1A 1ATAA 4Y71B 1EPGA 3NTGA 4E1GA 3U73A 2UWLB 1HX2A 2BOKL 2G00L 4X8UL 1XFEA 2YGQA 4MMYB 1W7XL 3CENL 2KB9A 4RRXA 3FCSB 1LPZA 1QIUA 3TGFA 4D0EA 3KCGL 4D90A 2I9AA 2M74A 2VH0B 3M37L 3ELAL 1G2LB 1UZJA 2XBWL 3EGFA 1I0UA 1ATBA 1NFXB 1P9JA 1EAIC 2BQWA 1YGCL 2ADXA 2UWPB 1IP0A 2B7DL 3GCXE 4CUFA 1LMJA 5JVYA 1L5GB 1F0RB 5CISA 3V65B 3Q7DA 4GU4A 1EPIA 3BT2A 2KV4A 2YGPA 1HJ7A 1XDTR 3QH0A 3NTBA 3DEMA 4TGFA 1EQGA 1NQLB 3LTFB 4Z0LA 4O02B 3SOVA 4A94C 1MQ5L 1XKAL 1IQJL 1JBUL 5KIRA 2WYGB 2W2QE 1EMNA 2W3IB 5JVZA 2YGOA 3P5BL 4ZXXL 1KLOA 2PHBB 1LQDA 3CFWA 2WYJB 1IQNL 2OYUP 1F7EA 2TGFA 1V3XB 1YUKB 3NT1A 2BQ7A 4COXA 3RR3A 2BT7A 4M10A 4JZDL 4AQTA 2WG3C 4GU3A 1KKEA 2FLGA 3PGHA 1FE2A 3SOQA 3H5CB 3C9AC 1EMOA 2XC5L 1PFXL 2VVVL 1CCVA 1IQKL 2VWOL 2Y7ZB 4BXWA 1HT5A 1ZAQA 4MMZB 4X8SL 3N8YA 1U67A 1L3YA 2P3UA 2BO2A 2RHPA 2WPKE 5L2ZL 2J34B 3LC5B 4YZUB 3LC3B 5L30L 3K9XA 1WHEA 1NZIA 3FBYA 3N8ZA 2Q1JB 2RA0L 3N8VA 3HPTA 3N8XA 1DX5I 2BOHA 3HO4A 1B9WA 4X8VL 4D0FA 4Y7BB 2HORA 3TBDA 2XBYL 2P3TA 3TZIA 1F7MA 3N8YB 3LIWB 1EZQB 2OYEP 3POYA 1BF9A 1V1IA 1OB1C 3F1SB 4JZFL 2EI7B 4CSYA 3V64C 2WZPP 4PH9A 3Q3KB 3GCWE 2P93L 5IKRA 4BTTA 2VH6B 1NPEB 4Y7AB 1ATDA 3IITB 4BXSA 1TOZA 5IKVA 2P26A 2P95L 4NGAL 4XLWA 3ASIA 4Z0KB 1C5MF 1HCGB 2JKHL 2EI6B 4Y79B 2RNLA 1PRHA 4ZAEB 4BTUA 1YUFA 2WPME 1FF7A 1KIGL 4ZHAB 2K2TA 2UWOB 1APOA 2PR3B 4NG9L 5IKTA 1LK9A 4RRWA 1TLEA 3KK6A 4BTIA 1CX2A 2Y38A 1CEJA 2P16L 5JBBE 1NFUB 1FJSL 2XBXL 4ZH8B 1HAEA 1LMMA 2VVUL 1NT0A 4XL1A 1G1SA 2GD4A 4Y6DB 5JB8E 3TH3L 1DIYA 4G1MB 1IVOC 4MMXB 2H9EL 4C16A 3GISX 2FD6A 1J9CL 1FSBA 3HS7A 2KNIA 2XBVL 3M36L 1O5DL 3NJPC 2W2OE 3MDLA 2NPRA 2J2UB 4OTJA 1G1QA 1IOEL 3TK6B 3KRKA 1HREA 1YO8A 1HAFA 1PTHA 1CVWL 1HRFA 1DDXA 1FAKL 1NFWB 2HOXA 1K37A 4JYVL 5IKQA 1G1TA 1IQHL 2BOXA 2Y82B 2VWNL 2AYLA 2J4IB 4FM5A 4JZEL 1KSNB 3ZYGA 4RRZA 1AUTL 2P3FN 1CVUA 1GK5A 4JYUL 5L2YL 2BSFA 4RRYA 2WPHE 2WFTA 1WU1B 4XBMA 1UZKA 5JB9E 2J95B 1HT8A 3U7UG 4M11A 3ZYIB 3KQBL 2F9BL 1IGXA 2WG4B 4RUTA 2P3FL 1IGZA 3F6UL 4BDXA 1NFYB 3SOBB 2VWMK 1APQA 2XC0L 2FLRL 2Y80B 2JJLA 2WFXB 3SW2A 1Z6CA 2DDUA 3ENSA 1P0SL 2P28B 3KQEL 2K2SB 3BPSE 1N7DA 3S6XA 4ISIL 4Z6AL 1YUGA 1JL9A 3KQCL 2J94B 2VWLL 1IQLL 2W2NE 2MHPA 4ISHL 5CKMA 2VRSA 2WPIE 5E8DA 1KLIL 2WPJE 1IJQA 3MQEA 5EGMB 1A3PA 3OLTA 3FFGL 2FLBL 2W3KB 1LPKA 4YT6L 1XKBA 4CUEA 2CJIB 3LTGD 4A7IA 2I9BA 3LN0A 5I46L 3BT1A 4LMFA 1N1IA 3OLUA 4LORA 3TK5B 4YT7L 5JBCE 2W86A 2Y5HL 1URKA 2Y5FL 3ZYJB 2MGRA 1MOXC 1Q4GA 3N8WA 1U8CB 2MGPA 3CS7L 2BZ6L 4RS0A 3QMOA 3HO3A 1PXXA 1ADXA
chains in the Genus database with same CATH topology
1IQEL 4BDWA 1TPGA 2BQ6A 1ATEA 2VJ3A 1K36A 1EQHA 2KL7A 1EGFA 2FZZL 5F19A 5CKNA 1F0SB 2BMGA 1PGEA 1MQ6L 2XC4L 1EPHA 3LAQA 3N8WB 4OTYA 2BOUA 1FAXL 4CUDA 5COXA 5FDQA 2D1JB 1W8BL 1IQML 1DVAL 5CKQA 2W2ME 2VVCK 2PUQL 3HS6A 1EBVA 1G2MB 3KQDL 1Z6EL 4ZXYL 1CCFA 2EI8B 2J38B 4NA9L 2W2PE 1FFMA 1KLJL 5F1AA 2Y7XB 1G1RA 2WPLE 1UZQA 3CA7A 1X7AL 6COXA 1QFKL 2Y81B 2H9EC 3R05A 5KN5C 1COUA 1HZ8A 1LPGA 2Y5GL 3LN1A 1SZBA 1M1XB 1RFNB 3HO5A 3HS5A 5K0HB 1UZPA 1JV2B 1IQGL 1IQFL 3KL6B 1EPJA 1IOXA 4O1ZA 1CQEA 3QCWA 1IQIL 5JBAE 2W26B 1DQBA 1WHFA 4X8TL 4Y76B 2P94L 3IJEB 5JW1A 1ATAA 4Y71B 1EPGA 3NTGA 4E1GA 3U73A 2UWLB 1HX2A 2BOKL 2G00L 4X8UL 1XFEA 2YGQA 4MMYB 1W7XL 3CENL 2KB9A 4RRXA 3FCSB 1LPZA 3TGFA 4D0EA 3KCGL 4D90A 2I9AA 2M74A 2VH0B 3M37L 3ELAL 1G2LB 1UZJA 2XBWL 3EGFA 1I0UA 1ATBA 1NFXB 1P9JA 1EAIC 2BQWA 1YGCL 2ADXA 2UWPB 1IP0A 2B7DL 3GCXE 4CUFA 1LMJA 5JVYA 1L5GB 1F0RB 5CISA 3V65B 3Q7DA 1EPIA 3BT2A 2KV4A 2YGPA 1HJ7A 1XDTR 3QH0A 3NTBA 3DEMA 4TGFA 1EQGA 1NQLB 3LTFB 4Z0LA 4O02B 3SOVA 4A94C 1MQ5L 1XKAL 1IQJL 1JBUL 5KIRA 2WYGB 2W2QE 1EMNA 2W3IB 5JVZA 2YGOA 3P5BL 4ZXXL 1KLOA 2PHBB 1LQDA 3CFWA 2WYJB 1IQNL 2OYUP 1F7EA 2TGFA 1V3XB 1YUKB 3NT1A 2BQ7A 4COXA 3RR3A 4M10A 4JZDL 4AQTA 2WG3C 2FLGA 3PGHA 3SOQA 1FE2A 3H5CB 3C9AC 1EMOA 2XC5L 1PFXL 2VVVL 1CCVA 1IQKL 2VWOL 2Y7ZB 4BXWA 1HT5A 1ZAQA 4MMZB 4X8SL 3N8YA 1U67A 1L3YA 2P3UA 2BO2A 2RHPA 2WPKE 5L2ZL 2J34B 3LC5B 4YZUB 3LC3B 5L30L 3K9XA 1WHEA 1NZIA 3FBYA 3N8ZA 2Q1JB 2RA0L 3N8VA 3HPTA 3N8XA 1DX5I 2BOHA 3HO4A 1B9WA 4X8VL 4D0FA 4Y7BB 3TBDA 2XBYL 2P3TA 3TZIA 1F7MA 3N8YB 3LIWB 1EZQB 2OYEP 3POYA 1BF9A 1OB1C 3F1SB 4JZFL 2EI7B 4CSYA 3V64C 2WZPP 4PH9A 3Q3KB 3GCWE 2P93L 5IKRA 4BTTA 2VH6B 1NPEB 4Y7AB 1ATDA 3IITB 4BXSA 1TOZA 5IKVA 2P26A 2P95L 4NGAL 4XLWA 3ASIA 4Z0KB 1C5MF 1HCGB 2JKHL 2EI6B 4Y79B 2RNLA 1PRHA 4ZAEB 4BTUA 1YUFA 2WPME 1FF7A 1KIGL 4ZHAB 2K2TA 2UWOB 1APOA 2PR3B 4NG9L 5IKTA 4RRWA 1TLEA 3KK6A 4BTIA 1CX2A 2Y38A 1CEJA 2P16L 5JBBE 1NFUB 1FJSL 2XBXL 4ZH8B 1HAEA 1LMMA 2VVUL 1NT0A 4XL1A 1G1SA 2GD4A 4Y6DB 5JB8E 3TH3L 1DIYA 4G1MB 1IVOC 4MMXB 2H9EL 4C16A 3GISX 2FD6A 1J9CL 1FSBA 3HS7A 2KNIA 2XBVL 3M36L 1O5DL 3NJPC 2W2OE 3MDLA 2NPRA 2J2UB 4OTJA 1G1QA 1IOEL 3TK6B 3KRKA 1HREA 1YO8A 1HAFA 1PTHA 1CVWL 1HRFA 1DDXA 1FAKL 1NFWB 4JYVL 1K37A 5IKQA 1G1TA 1IQHL 2BOXA 2Y82B 2VWNL 2AYLA 2J4IB 4FM5A 4JZEL 1KSNB 3ZYGA 4RRZA 1AUTL 2P3FN 1CVUA 1GK5A 4JYUL 5L2YL 4RRYA 2WPHE 2WFTA 1WU1B 4XBMA 1UZKA 5JB9E 2J95B 1HT8A 3U7UG 4M11A 3ZYIB 3KQBL 2F9BL 1IGXA 2WG4B 4RUTA 2P3FL 1IGZA 3F6UL 4BDXA 1NFYB 3SOBB 2VWMK 1APQA 2XC0L 2FLRL 2Y80B 2WFXB 3SW2A 1Z6CA 2DDUA 3ENSA 1P0SL 2P28B 3KQEL 2K2SB 3BPSE 1N7DA 3S6XA 4ISIL 4Z6AL 1YUGA 1JL9A 3KQCL 2J94B 2VWLL 1IQLL 2W2NE 2MHPA 4ISHL 5CKMA 2WPIE 5E8DA 1KLIL 2WPJE 1IJQA 3MQEA 5EGMB 1A3PA 3OLTA 3FFGL 2FLBL 2W3KB 1LPKA 4YT6L 1XKBA 4CUEA 2CJIB 3LTGD 4A7IA 2I9BA 3LN0A 5I46L 3BT1A 4LMFA 1N1IA 3OLUA 4LORA 3TK5B 4YT7L 5JBCE 2W86A 2Y5HL 1URKA 2Y5FL 3ZYJB 2MGRA 1MOXC 1Q4GA 3N8WA 1U8CB 2MGPA 3CS7L 2BZ6L 4RS0A 3QMOA 3HO3A 1PXXA 1ADXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IQE L;  4BDW A;  1TPG A;  2BQ6 A;  1ATE A;  2VJ3 A;  1K36 A;  1EQH A;  2KL7 A;  1EGF A;  2FZZ L;  5F19 A;  5CKN A;  1F0S B;  2BMG A;  1PGE A;  1MQ6 L;  2XC4 L;  1EPH A;  3LAQ A;  3N8W B;  4OTY A;  2BOU A;  1FAX L;  4CUD A;  5COX A;  5FDQ A;  2D1J B;  1W8B L;  1IQM L;  1DVA L;  5CKQ A;  2W2M E;  2VVC K;  2PUQ L;  3HS6 A;  1EBV A;  1G2M B;  3KQD L;  1Z6E L;  4ZXY L;  1CCF A;  2EI8 B;  2J38 B;  4NA9 L;  2W2P E;  1FFM A;  1KLJ L;  5F1A A;  2Y7X B;  1G1R A;  2WPL E;  1UZQ A;  3CA7 A;  1X7A L;  6COX A;  1QFK L;  2Y81 B;  3R05 A;  5KN5 C;  1COU A;  1HZ8 A;  1LPG A;  2Y5G L;  3LN1 A;  1SZB A;  1M1X B;  1RFN B;  3HO5 A;  3HS5 A;  5K0H B;  1UZP A;  1JV2 B;  1IQG L;  1IQF L;  3KL6 B;  1EPJ A;  1IOX A;  4O1Z A;  1CQE A;  3QCW A;  1IQI L;  5JBA E;  2W26 B;  1DQB A;  1WHF A;  4X8T L;  4Y76 B;  2P94 L;  3IJE B;  5JW1 A;  1ATA A;  4Y71 B;  1EPG A;  3NTG A;  4E1G A;  3U73 A;  2UWL B;  1HX2 A;  2BOK L;  2G00 L;  4X8U L;  1XFE A;  4MMY B;  1W7X L;  3CEN L;  2KB9 A;  4RRX A;  3FCS B;  1LPZ A;  3TGF A;  4D0E A;  3KCG L;  4D90 A;  2I9A A;  2M74 A;  2VH0 B;  3M37 L;  3ELA L;  1G2L B;  1UZJ A;  2XBW L;  3EGF A;  1I0U A;  1ATB A;  1NFX B;  1P9J A;  1EAI C;  2BQW A;  1YGC L;  2ADX A;  2UWP B;  1IP0 A;  2B7D L;  3GCX E;  4CUF A;  1LMJ A;  5JVY A;  1L5G B;  1F0R B;  5CIS A;  3V65 B;  3Q7D A;  1EPI A;  3BT2 A;  2KV4 A;  2YGP A;  1HJ7 A;  1XDT R;  3QH0 A;  3NTB A;  3DEM A;  4TGF A;  1EQG A;  1NQL B;  3LTF B;  4Z0L A;  4O02 B;  3SOV A;  1MQ5 L;  1XKA L;  1IQJ L;  1JBU L;  5KIR A;  2WYG B;  2W2Q E;  1EMN A;  2W3I B;  5JVZ A;  2YGO A;  3P5B L;  4ZXX L;  1KLO A;  2PHB B;  1LQD A;  3CFW A;  2WYJ B;  1IQN L;  2OYU P;  1F7E A;  2TGF A;  1V3X B;  1YUK B;  3NT1 A;  2BQ7 A;  4COX A;  3RR3 A;  4M10 A;  4JZD L;  4AQT A;  2WG3 C;  2FLG A;  3PGH A;  3SOQ A;  1FE2 A;  3H5C B;  3C9A C;  1EMO A;  2XC5 L;  1PFX L;  2VVV L;  1CCV A;  1IQK L;  2VWO L;  2Y7Z B;  4BXW A;  1HT5 A;  1ZAQ A;  4MMZ B;  4X8S L;  3N8Y A;  1U67 A;  1L3Y A;  2P3U A;  2BO2 A;  2RHP A;  2WPK E;  5L2Z L;  2J34 B;  3LC5 B;  4YZU B;  3LC3 B;  5L30 L;  3K9X A;  1WHE A;  1NZI A;  3FBY A;  3N8Z A;  2Q1J B;  2RA0 L;  3N8V A;  3HPT A;  3N8X A;  1DX5 I;  2BOH A;  3HO4 A;  1B9W A;  4X8V L;  4D0F A;  4Y7B B;  3TBD A;  2XBY L;  2P3T A;  3TZI A;  1F7M A;  3N8Y B;  3LIW B;  1EZQ B;  2OYE P;  3POY A;  1BF9 A;  1OB1 C;  3F1S B;  4JZF L;  2EI7 B;  4CSY A;  3V64 C;  4PH9 A;  3Q3K B;  3GCW E;  2P93 L;  5IKR A;  4BTT A;  2VH6 B;  1NPE B;  4Y7A B;  1ATD A;  3IIT B;  4BXS A;  1TOZ A;  5IKV A;  2P26 A;  2P95 L;  4NGA L;  4XLW A;  3ASI A;  4Z0K B;  1C5M F;  1HCG B;  2JKH L;  2EI6 B;  4Y79 B;  2RNL A;  1PRH A;  4ZAE B;  4BTU A;  1YUF A;  2WPM E;  1FF7 A;  1KIG L;  4ZHA B;  2K2T A;  2UWO B;  1APO A;  2PR3 B;  4NG9 L;  5IKT A;  4RRW A;  1TLE A;  3KK6 A;  4BTI A;  1CX2 A;  2Y38 A;  1CEJ A;  2P16 L;  5JBB E;  1NFU B;  1FJS L;  2XBX L;  4ZH8 B;  1HAE A;  2VVU L;  1NT0 A;  4XL1 A;  1G1S A;  2GD4 A;  4Y6D B;  5JB8 E;  3TH3 L;  1DIY A;  4G1M B;  1IVO C;  4MMX B;  2H9E L;  4C16 A;  3GIS X;  2FD6 A;  1J9C L;  1FSB A;  3HS7 A;  2XBV L;  3M36 L;  1O5D L;  3NJP C;  2W2O E;  3MDL A;  2NPR A;  2J2U B;  4OTJ A;  1G1Q A;  1IOE L;  3TK6 B;  3KRK A;  1HRE A;  1YO8 A;  1HAF A;  1PTH A;  1CVW L;  1HRF A;  1DDX A;  1FAK L;  1NFW B;  4JYV L;  1K37 A;  5IKQ A;  1G1T A;  1IQH L;  2BOX A;  2Y82 B;  2VWN L;  2AYL A;  2J4I B;  4FM5 A;  4JZE L;  1KSN B;  3ZYG A;  4RRZ A;  1AUT L;  2P3F N;  1CVU A;  1GK5 A;  4JYU L;  5L2Y L;  4RRY A;  2WPH E;  2WFT A;  1WU1 B;  4XBM A;  1UZK A;  5JB9 E;  2J95 B;  1HT8 A;  3U7U G;  4M11 A;  3ZYI B;  3KQB L;  2F9B L;  1IGX A;  2WG4 B;  4RUT A;  2P3F L;  1IGZ A;  3F6U L;  4BDX A;  1NFY B;  3SOB B;  2VWM K;  1APQ A;  2XC0 L;  2FLR L;  2Y80 B;  2WFX B;  3SW2 A;  1Z6C A;  2DDU A;  3ENS A;  1P0S L;  2P28 B;  3KQE L;  2K2S B;  3BPS E;  1N7D A;  4ISI L;  4Z6A L;  1YUG A;  1JL9 A;  3KQC L;  2J94 B;  2VWL L;  1IQL L;  2W2N E;  2MHP A;  4ISH L;  5CKM A;  2WPI E;  5E8D A;  1KLI L;  2WPJ E;  1IJQ A;  3MQE A;  5EGM B;  1A3P A;  3OLT A;  3FFG L;  2FLB L;  2W3K B;  1LPK A;  4YT6 L;  1XKB A;  4CUE A;  2CJI B;  3LTG D;  4A7I A;  2I9B A;  3LN0 A;  5I46 L;  3BT1 A;  4LMF A;  1N1I A;  3OLU A;  4LOR A;  3TK5 B;  4YT7 L;  5JBC E;  2W86 A;  2Y5H L;  1URK A;  2Y5F L;  3ZYJ B;  2MGR A;  1MOX C;  1Q4G A;  3N8W A;  1U8C B;  2MGP A;  3CS7 L;  2BZ6 L;  4RS0 A;  3QMO A;  3HO3 A;  1PXX A;  1ADX A; 
#chains in the Genus database with same CATH topology
 1IQE L;  4BDW A;  1TPG A;  2BQ6 A;  1ATE A;  2VJ3 A;  1K36 A;  1EQH A;  2KL7 A;  1EGF A;  2FZZ L;  5F19 A;  5CKN A;  1F0S B;  2BMG A;  1PGE A;  1MQ6 L;  2XC4 L;  1EPH A;  3LAQ A;  3N8W B;  4OTY A;  2BOU A;  1FAX L;  4CUD A;  5COX A;  5FDQ A;  2D1J B;  1V1H A;  1W8B L;  1IQM L;  1DVA L;  5CKQ A;  2W2M E;  2VVC K;  2PUQ L;  3HS6 A;  1EBV A;  1G2M B;  3KQD L;  1Z6E L;  4ZXY L;  1CCF A;  2EI8 B;  2J38 B;  4NA9 L;  2W2P E;  1FFM A;  1KLJ L;  5F1A A;  2Y7X B;  1G1R A;  2WPL E;  1UZQ A;  3CA7 A;  1X7A L;  6COX A;  1QFK L;  2Y81 B;  2H9E C;  3R05 A;  5KN5 C;  1COU A;  1HZ8 A;  1LPG A;  2Y5G L;  3LN1 A;  1SZB A;  1M1X B;  1RFN B;  3HO5 A;  3HS5 A;  5K0H B;  1UZP A;  1JV2 B;  2BT8 A;  1IQG L;  1IQF L;  3KL6 B;  1EPJ A;  1IOX A;  4O1Z A;  1CQE A;  3QCW A;  1IQI L;  5JBA E;  2W26 B;  1DQB A;  1WHF A;  4X8T L;  4Y76 B;  2P94 L;  3IJE B;  5JW1 A;  1ATA A;  4Y71 B;  1EPG A;  3NTG A;  4E1G A;  3U73 A;  2UWL B;  1HX2 A;  2BOK L;  2G00 L;  4X8U L;  1XFE A;  2YGQ A;  4MMY B;  1W7X L;  3CEN L;  2KB9 A;  4RRX A;  3FCS B;  1LPZ A;  1QIU A;  3TGF A;  4D0E A;  3KCG L;  4D90 A;  2I9A A;  2M74 A;  2VH0 B;  3M37 L;  3ELA L;  1G2L B;  1UZJ A;  2XBW L;  3EGF A;  1I0U A;  1ATB A;  1NFX B;  1P9J A;  1EAI C;  2BQW A;  1YGC L;  2ADX A;  2UWP B;  1IP0 A;  2B7D L;  3GCX E;  4CUF A;  1LMJ A;  5JVY A;  1L5G B;  1F0R B;  5CIS A;  3V65 B;  3Q7D A;  4GU4 A;  1EPI A;  3BT2 A;  2KV4 A;  2YGP A;  1HJ7 A;  1XDT R;  3QH0 A;  3NTB A;  3DEM A;  4TGF A;  1EQG A;  1NQL B;  3LTF B;  4Z0L A;  4O02 B;  3SOV A;  4A94 C;  1MQ5 L;  1XKA L;  1IQJ L;  1JBU L;  5KIR A;  2WYG B;  2W2Q E;  1EMN A;  2W3I B;  5JVZ A;  2YGO A;  3P5B L;  4ZXX L;  1KLO A;  2PHB B;  1LQD A;  3CFW A;  2WYJ B;  1IQN L;  2OYU P;  1F7E A;  2TGF A;  1V3X B;  1YUK B;  3NT1 A;  2BQ7 A;  4COX A;  3RR3 A;  2BT7 A;  4M10 A;  4JZD L;  4AQT A;  2WG3 C;  4GU3 A;  1KKE A;  2FLG A;  3PGH A;  1FE2 A;  3SOQ A;  3H5C B;  3C9A C;  1EMO A;  2XC5 L;  1PFX L;  2VVV L;  1CCV A;  1IQK L;  2VWO L;  2Y7Z B;  4BXW A;  1HT5 A;  1ZAQ A;  4MMZ B;  4X8S L;  3N8Y A;  1U67 A;  1L3Y A;  2P3U A;  2BO2 A;  2RHP A;  2WPK E;  5L2Z L;  2J34 B;  3LC5 B;  4YZU B;  3LC3 B;  5L30 L;  3K9X A;  1WHE A;  1NZI A;  3FBY A;  3N8Z A;  2Q1J B;  2RA0 L;  3N8V A;  3HPT A;  3N8X A;  1DX5 I;  2BOH A;  3HO4 A;  1B9W A;  4X8V L;  4D0F A;  4Y7B B;  2HOR A;  3TBD A;  2XBY L;  2P3T A;  3TZI A;  1F7M A;  3N8Y B;  3LIW B;  1EZQ B;  2OYE P;  3POY A;  1BF9 A;  1V1I A;  1OB1 C;  3F1S B;  4JZF L;  2EI7 B;  4CSY A;  3V64 C;  2WZP P;  4PH9 A;  3Q3K B;  3GCW E;  2P93 L;  5IKR A;  4BTT A;  2VH6 B;  1NPE B;  4Y7A B;  1ATD A;  3IIT B;  4BXS A;  1TOZ A;  5IKV A;  2P26 A;  2P95 L;  4NGA L;  4XLW A;  3ASI A;  4Z0K B;  1C5M F;  1HCG B;  2JKH L;  2EI6 B;  4Y79 B;  2RNL A;  1PRH A;  4ZAE B;  4BTU A;  1YUF A;  2WPM E;  1FF7 A;  1KIG L;  4ZHA B;  2K2T A;  2UWO B;  1APO A;  2PR3 B;  4NG9 L;  5IKT A;  1LK9 A;  4RRW A;  1TLE A;  3KK6 A;  4BTI A;  1CX2 A;  2Y38 A;  1CEJ A;  2P16 L;  5JBB E;  1NFU B;  1FJS L;  2XBX L;  4ZH8 B;  1HAE A;  1LMM A;  2VVU L;  1NT0 A;  4XL1 A;  1G1S A;  2GD4 A;  4Y6D B;  5JB8 E;  3TH3 L;  1DIY A;  4G1M B;  1IVO C;  4MMX B;  2H9E L;  4C16 A;  3GIS X;  2FD6 A;  1J9C L;  1FSB A;  3HS7 A;  2KNI A;  2XBV L;  3M36 L;  1O5D L;  3NJP C;  2W2O E;  3MDL A;  2NPR A;  2J2U B;  4OTJ A;  1G1Q A;  1IOE L;  3TK6 B;  3KRK A;  1HRE A;  1YO8 A;  1HAF A;  1PTH A;  1CVW L;  1HRF A;  1DDX A;  1FAK L;  1NFW B;  2HOX A;  1K37 A;  4JYV L;  5IKQ A;  1G1T A;  1IQH L;  2BOX A;  2Y82 B;  2VWN L;  2AYL A;  2J4I B;  4FM5 A;  4JZE L;  1KSN B;  3ZYG A;  4RRZ A;  1AUT L;  2P3F N;  1CVU A;  1GK5 A;  4JYU L;  5L2Y L;  2BSF A;  4RRY A;  2WPH E;  2WFT A;  1WU1 B;  4XBM A;  1UZK A;  5JB9 E;  2J95 B;  1HT8 A;  3U7U G;  4M11 A;  3ZYI B;  3KQB L;  2F9B L;  1IGX A;  2WG4 B;  4RUT A;  2P3F L;  1IGZ A;  3F6U L;  4BDX A;  1NFY B;  3SOB B;  2VWM K;  1APQ A;  2XC0 L;  2FLR L;  2Y80 B;  2JJL A;  2WFX B;  3SW2 A;  1Z6C A;  2DDU A;  3ENS A;  1P0S L;  2P28 B;  3KQE L;  2K2S B;  3BPS E;  1N7D A;  3S6X A;  4ISI L;  4Z6A L;  1YUG A;  1JL9 A;  3KQC L;  2J94 B;  2VWL L;  1IQL L;  2W2N E;  2MHP A;  4ISH L;  5CKM A;  2VRS A;  2WPI E;  5E8D A;  1KLI L;  2WPJ E;  1IJQ A;  3MQE A;  5EGM B;  1A3P A;  3OLT A;  3FFG L;  2FLB L;  2W3K B;  1LPK A;  4YT6 L;  1XKB A;  4CUE A;  2CJI B;  3LTG D;  4A7I A;  2I9B A;  3LN0 A;  5I46 L;  3BT1 A;  4LMF A;  1N1I A;  3OLU A;  4LOR A;  3TK5 B;  4YT7 L;  5JBC E;  2W86 A;  2Y5H L;  1URK A;  2Y5F L;  3ZYJ B;  2MGR A;  1MOX C;  1Q4G A;  3N8W A;  1U8C B;  2MGP A;  3CS7 L;  2BZ6 L;  4RS0 A;  3QMO A;  3HO3 A;  1PXX A;  1ADX A; 
#chains in the Genus database with same CATH homology
 1IQE L;  4BDW A;  1TPG A;  2BQ6 A;  1ATE A;  2VJ3 A;  1K36 A;  1EQH A;  2KL7 A;  1EGF A;  2FZZ L;  5F19 A;  5CKN A;  1F0S B;  2BMG A;  1PGE A;  1MQ6 L;  2XC4 L;  1EPH A;  3LAQ A;  3N8W B;  4OTY A;  2BOU A;  1FAX L;  4CUD A;  5COX A;  5FDQ A;  2D1J B;  1W8B L;  1IQM L;  1DVA L;  5CKQ A;  2W2M E;  2VVC K;  2PUQ L;  3HS6 A;  1EBV A;  1G2M B;  3KQD L;  1Z6E L;  4ZXY L;  1CCF A;  2EI8 B;  2J38 B;  4NA9 L;  2W2P E;  1FFM A;  1KLJ L;  5F1A A;  2Y7X B;  1G1R A;  2WPL E;  1UZQ A;  3CA7 A;  1X7A L;  6COX A;  1QFK L;  2Y81 B;  2H9E C;  3R05 A;  5KN5 C;  1COU A;  1HZ8 A;  1LPG A;  2Y5G L;  3LN1 A;  1SZB A;  1M1X B;  1RFN B;  3HO5 A;  3HS5 A;  5K0H B;  1UZP A;  1JV2 B;  1IQG L;  1IQF L;  3KL6 B;  1EPJ A;  1IOX A;  4O1Z A;  1CQE A;  3QCW A;  1IQI L;  5JBA E;  2W26 B;  1DQB A;  1WHF A;  4X8T L;  4Y76 B;  2P94 L;  3IJE B;  5JW1 A;  1ATA A;  4Y71 B;  1EPG A;  3NTG A;  4E1G A;  3U73 A;  2UWL B;  1HX2 A;  2BOK L;  2G00 L;  4X8U L;  1XFE A;  2YGQ A;  4MMY B;  1W7X L;  3CEN L;  2KB9 A;  4RRX A;  3FCS B;  1LPZ A;  3TGF A;  4D0E A;  3KCG L;  4D90 A;  2I9A A;  2M74 A;  2VH0 B;  3M37 L;  3ELA L;  1G2L B;  1UZJ A;  2XBW L;  3EGF A;  1I0U A;  1ATB A;  1NFX B;  1P9J A;  1EAI C;  2BQW A;  1YGC L;  2ADX A;  2UWP B;  1IP0 A;  2B7D L;  3GCX E;  4CUF A;  1LMJ A;  5JVY A;  1L5G B;  1F0R B;  5CIS A;  3V65 B;  3Q7D A;  1EPI A;  3BT2 A;  2KV4 A;  2YGP A;  1HJ7 A;  1XDT R;  3QH0 A;  3NTB A;  3DEM A;  4TGF A;  1EQG A;  1NQL B;  3LTF B;  4Z0L A;  4O02 B;  3SOV A;  4A94 C;  1MQ5 L;  1XKA L;  1IQJ L;  1JBU L;  5KIR A;  2WYG B;  2W2Q E;  1EMN A;  2W3I B;  5JVZ A;  2YGO A;  3P5B L;  4ZXX L;  1KLO A;  2PHB B;  1LQD A;  3CFW A;  2WYJ B;  1IQN L;  2OYU P;  1F7E A;  2TGF A;  1V3X B;  1YUK B;  3NT1 A;  2BQ7 A;  4COX A;  3RR3 A;  4M10 A;  4JZD L;  4AQT A;  2WG3 C;  2FLG A;  3PGH A;  3SOQ A;  1FE2 A;  3H5C B;  3C9A C;  1EMO A;  2XC5 L;  1PFX L;  2VVV L;  1CCV A;  1IQK L;  2VWO L;  2Y7Z B;  4BXW A;  1HT5 A;  1ZAQ A;  4MMZ B;  4X8S L;  3N8Y A;  1U67 A;  1L3Y A;  2P3U A;  2BO2 A;  2RHP A;  2WPK E;  5L2Z L;  2J34 B;  3LC5 B;  4YZU B;  3LC3 B;  5L30 L;  3K9X A;  1WHE A;  1NZI A;  3FBY A;  3N8Z A;  2Q1J B;  2RA0 L;  3N8V A;  3HPT A;  3N8X A;  1DX5 I;  2BOH A;  3HO4 A;  1B9W A;  4X8V L;  4D0F A;  4Y7B B;  3TBD A;  2XBY L;  2P3T A;  3TZI A;  1F7M A;  3N8Y B;  3LIW B;  1EZQ B;  2OYE P;  3POY A;  1BF9 A;  1OB1 C;  3F1S B;  4JZF L;  2EI7 B;  4CSY A;  3V64 C;  2WZP P;  4PH9 A;  3Q3K B;  3GCW E;  2P93 L;  5IKR A;  4BTT A;  2VH6 B;  1NPE B;  4Y7A B;  1ATD A;  3IIT B;  4BXS A;  1TOZ A;  5IKV A;  2P26 A;  2P95 L;  4NGA L;  4XLW A;  3ASI A;  4Z0K B;  1C5M F;  1HCG B;  2JKH L;  2EI6 B;  4Y79 B;  2RNL A;  1PRH A;  4ZAE B;  4BTU A;  1YUF A;  2WPM E;  1FF7 A;  1KIG L;  4ZHA B;  2K2T A;  2UWO B;  1APO A;  2PR3 B;  4NG9 L;  5IKT A;  4RRW A;  1TLE A;  3KK6 A;  4BTI A;  1CX2 A;  2Y38 A;  1CEJ A;  2P16 L;  5JBB E;  1NFU B;  1FJS L;  2XBX L;  4ZH8 B;  1HAE A;  1LMM A;  2VVU L;  1NT0 A;  4XL1 A;  1G1S A;  2GD4 A;  4Y6D B;  5JB8 E;  3TH3 L;  1DIY A;  4G1M B;  1IVO C;  4MMX B;  2H9E L;  4C16 A;  3GIS X;  2FD6 A;  1J9C L;  1FSB A;  3HS7 A;  2KNI A;  2XBV L;  3M36 L;  1O5D L;  3NJP C;  2W2O E;  3MDL A;  2NPR A;  2J2U B;  4OTJ A;  1G1Q A;  1IOE L;  3TK6 B;  3KRK A;  1HRE A;  1YO8 A;  1HAF A;  1PTH A;  1CVW L;  1HRF A;  1DDX A;  1FAK L;  1NFW B;  4JYV L;  1K37 A;  5IKQ A;  1G1T A;  1IQH L;  2BOX A;  2Y82 B;  2VWN L;  2AYL A;  2J4I B;  4FM5 A;  4JZE L;  1KSN B;  3ZYG A;  4RRZ A;  1AUT L;  2P3F N;  1CVU A;  1GK5 A;  4JYU L;  5L2Y L;  4RRY A;  2WPH E;  2WFT A;  1WU1 B;  4XBM A;  1UZK A;  5JB9 E;  2J95 B;  1HT8 A;  3U7U G;  4M11 A;  3ZYI B;  3KQB L;  2F9B L;  1IGX A;  2WG4 B;  4RUT A;  2P3F L;  1IGZ A;  3F6U L;  4BDX A;  1NFY B;  3SOB B;  2VWM K;  1APQ A;  2XC0 L;  2FLR L;  2Y80 B;  2WFX B;  3SW2 A;  1Z6C A;  2DDU A;  3ENS A;  1P0S L;  2P28 B;  3KQE L;  2K2S B;  3BPS E;  1N7D A;  3S6X A;  4ISI L;  4Z6A L;  1YUG A;  1JL9 A;  3KQC L;  2J94 B;  2VWL L;  1IQL L;  2W2N E;  2MHP A;  4ISH L;  5CKM A;  2WPI E;  5E8D A;  1KLI L;  2WPJ E;  1IJQ A;  3MQE A;  5EGM B;  1A3P A;  3OLT A;  3FFG L;  2FLB L;  2W3K B;  1LPK A;  4YT6 L;  1XKB A;  4CUE A;  2CJI B;  3LTG D;  4A7I A;  2I9B A;  3LN0 A;  5I46 L;  3BT1 A;  4LMF A;  1N1I A;  3OLU A;  4LOR A;  3TK5 B;  4YT7 L;  5JBC E;  2W86 A;  2Y5H L;  1URK A;  2Y5F L;  3ZYJ B;  2MGR A;  1MOX C;  1Q4G A;  3N8W A;  1U8C B;  2MGP A;  3CS7 L;  2BZ6 L;  4RS0 A;  3QMO A;  3HO3 A;  1PXX A;  1ADX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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