2C45A

Native precursor of pyruvoyl dependent aspartate decarboxylase
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
113
structure length
113
Chain Sequence
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of uncleaved L-aspartate-alpha-decarboxylase from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule tags Lyase
source organism Mycobacterium tuberculosis
molecule keywords Aspartate 1-decarboxylase
total genus 27
structure length 113
sequence length 113
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2005-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2c45A00
3TIWA 5C1BA 3QQ8A 2JA5A 1SFOA 1I50A 2R92A 3GTQA 1CZ5A 4KDLA 1I3QA 1CR5A 1TWAA 2V45A 3FKIA 3GTKA 1DMSA 4KDIA 5FTLA 3GTJA 2JIRA 3HU2A 2R93A 2NYAA 2B63A 1QCSA 4CS0A 4AZDA 2Y0SA 2NAPA 4GA6A 1AA6A 1SIWA 2IV2X 1Y1VA 1E32A 1E60A 4KODA 3CF2A 1FDOA 1UHEA 1PT1A 1PT0A 3PLXB 1TWHA 2R7ZA 2EEOB 1H0HA 1TWFA 1PQEA 2JIOA 2JIQA 4CRZA 1KQGA 3GTMA 1Y5IA 2JIMA 3QWZA 4DMRA 2WB1A 1R7RA 1KQFA 4QIWA 4RV0A 3GTPA 1FDIA 5GLFA 2VPYA 1H5NA 2JA6A 5FTJA 4KLNA 1TMOA 3ML1A 3DMRA 5FTMA 1PQHA 3GTOA 1G8KA 3IR5A 3TM7B 4GA5A 4KO8A 5FTKA 4CRYG 1E5VA 3IR6A 1IW7D 1TWCA 4AYBA 3IR7A 2E2IA 5DYGA 4AAYA 1YLEA 1Y1WA 3OUGA 5B6CA 4D7ZB 1R27A 1PPYA 2YU9A 1QDNA 2DMRA 1AW8B 4AONB 1VC3B 2WAQA 1Y4ZA 5T5ID 1K83A 2NVYA 1DMRA 5EPPA 3CQZA 1PYQA 3GTLA 3GTGA 2E2HA 2JIPA 2VPXA 1UHDA 2C45A 3O5AA 5C18A 1R9TA 5FTNA 2PJHB 2NVXA 1E18A 2VPWA 1EU1A 1WLFA 3HKZA 1S3SA 1Q16A 3HU3A 3QC8A 1E61A 1TWGA 4C2MA 2PMZA 2JA7A 3QQ7A 2E7ZA 2V3VA 3HU1A 2VPZA 3H0GA 2VUMA 1G8JA 2KI8A 1CZ4A 1WCMA 1PYUB 1PQFA 1OGYA 5T5MD 5DYIA 4AOKB
chains in the Genus database with same CATH superfamily
3TIWA 5C1BA 3QQ8A 2JA5A 1SFOA 1I50A 2R92A 3GTQA 3SUJA 1CZ5A 4KDLA 1I3QA 1CR5A 1TWAA 2V45A 1ZYRD 2A69D 3FKIA 2G6GA 3GTKA 2PNWA 3ENGA 3X2GA 1DMSA 4KDIA 5GM9A 5FTLA 3GTJA 3X2JA 2G5DA 2JIRA 3HU2A 2CW0D 4FFTA 3X2NA 4JJOA 3SUMA 2R93A 2NYAA 2BH0A 2B63A 1QCSA 4CS0A 4AZDA 2Y0SA 2NAPA 4GA6A 1AA6A 1SIWA 2IV2X 1Y1VA 1HD5A 1E32A 4NOHA 4ENGA 1E60A 4KODA 4FG2A 2PICA 1FDOA 3CF2A 2BE5D 1UHEA 1PT1A 1ZC1A 3X2LA 4L48A 1PT0A 5H4UA 3PLXB 1TWHA 2A68D 2R7ZA 2EEOB 1H0HA 1TWFA 1PQEA 1N10A 2JIOA 2JIQA 2PJJA 4CRZA 1KQGA 3SUKA 3GTMA 1Y5IA 1OA9A 1L8FA 2JIMA 3QWZA 3X2OA 2YUJA 3X2HA 4DMRA 2WB1A 1R7RA 4JP7A 3D30A 1KQFA 4QIWA 4RV0A 3GTPA 1FDIA 5GLFA 2VPYA 1WC2A 1H5NA 2JA6A 5FTJA 4KLNA 1TMOA 3ML1A 3DMRA 5FTMA 1PQHA 3GTOA 1G8KA 1OA7A 3IR5A 3TM7B 4GA5A 4KO8A 5FTKA 4JP6A 4CRYG 3SULA 1E5VA 1YNJD 3CZBA 2AE0X 3IR6A 1IW7D 1TWCA 4AYBA 3IR7A 2E2IA 2HCZX 5DYGA 4AAYA 5GLYA 4ZM7A 1YLEA 1Y1WA 1BW4A 3OUGA 5B6CA 3X2PA 4D7ZB 1R27A 1SMYD 1PPYA 2YU9A 1QDNA 2DMRA 1AW8B 2ENGA 4AONB 1VC3B 1Y4ZA 2WAQA 5T5ID 1K83A 2NVYA 1DMRA 5EPPA 3CQZA 1PYQA 3GTLA 3GTGA 2E2HA 2JIPA 2VPXA 1UHDA 2C45A 2GAEA 3X2MA 3O5AA 5C18A 1R9TA 5FTNA 2PJHB 4FG4A 2NVXA 1E18A 2VPWA 1EU1A 4JS7A 1WLFA 3X2KA 3HKZA 1S3SA 1Q16A 1YNND 3HU3A 3QC8A 5GLXA 4JCWA 1E61A 1TWGA 4C2MA 2A6ED 2PMZA 4AVRA 2JA7A 3QQ7A 2E7ZA 2V3VA 3HU1A 2VPZA 3H0GA 3X2IA 2PI8A 3M3GA 2VUMA 1G8JA 4FERA 2KQAA 2KI8A 1CZ4A 1WCMA 1PYUB 1PQFA 1BW3A 1OGYA 2O5JD 5T5MD 5DYIA 2A6HD 4AOKB
chains in the Genus database with same CATH topology
3TIWA 5C1BA 3QQ8A 2JA5A 1SFOA 1I50A 2R92A 3GTQA 1CZ5A 4KDLA 1I3QA 1CR5A 1TWAA 2V45A 1ZYRD 2A69D 3FKIA 2G6GA 3GTKA 2PNWA 1DMSA 4KDIA 5FTLA 3GTJA 2G5DA 2JIRA 3HU2A 2CW0D 2R93A 2NYAA 2B63A 1QCSA 4CS0A 4AZDA 2Y0SA 2NAPA 4GA6A 1AA6A 1SIWA 2IV2X 1Y1VA 1E32A 4NOHA 1E60A 4KODA 2PICA 1FDOA 3CF2A 2BE5D 1UHEA 1PT1A 1ZC1A 1PT0A 3PLXB 1TWHA 2A68D 2R7ZA 2EEOB 1H0HA 1TWFA 1PQEA 2JIOA 2JIQA 2PJJA 4CRZA 1KQGA 3GTMA 1Y5IA 2JIMA 3QWZA 2YUJA 4DMRA 2WB1A 1R7RA 1KQFA 4QIWA 4RV0A 3GTPA 1FDIA 5GLFA 2VPYA 1H5NA 2JA6A 5FTJA 4KLNA 1TMOA 3ML1A 3DMRA 5FTMA 1PQHA 3GTOA 1G8KA 3IR5A 3TM7B 4GA5A 4KO8A 5FTKA 4CRYG 1E5VA 1YNJD 3CZBA 2AE0X 3IR6A 1IW7D 1TWCA 4AYBA 3IR7A 2E2IA 5DYGA 4AAYA 1YLEA 1Y1WA 3OUGA 5B6CA 4D7ZB 1R27A 1SMYD 1PPYA 2YU9A 1QDNA 2DMRA 1AW8B 4AONB 1VC3B 1Y4ZA 2WAQA 5T5ID 1K83A 2NVYA 1DMRA 5EPPA 3CQZA 1PYQA 3GTLA 3GTGA 2E2HA 2JIPA 2VPXA 1UHDA 2C45A 2GAEA 3O5AA 5C18A 1R9TA 5FTNA 2PJHB 2NVXA 1E18A 2VPWA 1EU1A 1WLFA 3HKZA 1S3SA 1Q16A 1YNND 3HU3A 3QC8A 1E61A 1TWGA 4C2MA 2A6ED 2PMZA 2JA7A 3QQ7A 2E7ZA 2V3VA 3HU1A 2VPZA 3H0GA 2PI8A 2VUMA 1G8JA 2KI8A 1CZ4A 1WCMA 1PYUB 1PQFA 1OGYA 2O5JD 5T5MD 5DYIA 2A6HD 4AOKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TIW A;  5C1B A;  3QQ8 A;  2JA5 A;  1SFO A;  1I50 A;  2R92 A;  3GTQ A;  1CZ5 A;  4KDL A;  1I3Q A;  1CR5 A;  1TWA A;  2V45 A;  3FKI A;  3GTK A;  1DMS A;  4KDI A;  5FTL A;  3GTJ A;  2JIR A;  3HU2 A;  2R93 A;  2NYA A;  2B63 A;  1QCS A;  4CS0 A;  4AZD A;  2Y0S A;  2NAP A;  4GA6 A;  1AA6 A;  1SIW A;  2IV2 X;  1Y1V A;  1E32 A;  1E60 A;  4KOD A;  3CF2 A;  1FDO A;  1UHE A;  1PT1 A;  1PT0 A;  3PLX B;  1TWH A;  2R7Z A;  2EEO B;  1H0H A;  1TWF A;  1PQE A;  2JIO A;  2JIQ A;  4CRZ A;  1KQG A;  3GTM A;  1Y5I A;  2JIM A;  3QWZ A;  4DMR A;  2WB1 A;  1R7R A;  1KQF A;  4QIW A;  4RV0 A;  3GTP A;  1FDI A;  5GLF A;  2VPY A;  1H5N A;  2JA6 A;  5FTJ A;  4KLN A;  1TMO A;  3ML1 A;  3DMR A;  5FTM A;  1PQH A;  3GTO A;  1G8K A;  3IR5 A;  3TM7 B;  4GA5 A;  4KO8 A;  5FTK A;  4CRY G;  1E5V A;  3IR6 A;  1IW7 D;  1TWC A;  4AYB A;  3IR7 A;  2E2I A;  5DYG A;  4AAY A;  1YLE A;  1Y1W A;  3OUG A;  5B6C A;  4D7Z B;  1R27 A;  1PPY A;  2YU9 A;  1QDN A;  2DMR A;  1AW8 B;  4AON B;  1VC3 B;  2WAQ A;  1Y4Z A;  5T5I D;  1K83 A;  2NVY A;  1DMR A;  5EPP A;  3CQZ A;  1PYQ A;  3GTL A;  3GTG A;  2E2H A;  2JIP A;  2VPX A;  1UHD A;  2C45 A;  3O5A A;  5C18 A;  1R9T A;  5FTN A;  2PJH B;  2NVX A;  1E18 A;  2VPW A;  1EU1 A;  1WLF A;  3HKZ A;  1S3S A;  1Q16 A;  3HU3 A;  3QC8 A;  1E61 A;  1TWG A;  4C2M A;  2PMZ A;  2JA7 A;  3QQ7 A;  2E7Z A;  2V3V A;  3HU1 A;  2VPZ A;  3H0G A;  2VUM A;  1G8J A;  2KI8 A;  1CZ4 A;  1WCM A;  1PYU B;  1PQF A;  1OGY A;  5T5M D;  5DYI A;  4AOK B; 
#chains in the Genus database with same CATH topology
 3TIW A;  5C1B A;  3QQ8 A;  2JA5 A;  1SFO A;  1I50 A;  2R92 A;  3GTQ A;  3SUJ A;  1CZ5 A;  4KDL A;  1I3Q A;  1CR5 A;  1TWA A;  2V45 A;  1ZYR D;  2A69 D;  3FKI A;  2G6G A;  3GTK A;  2PNW A;  3ENG A;  3X2G A;  1DMS A;  4KDI A;  5GM9 A;  5FTL A;  3GTJ A;  3X2J A;  2G5D A;  2JIR A;  3HU2 A;  2CW0 D;  4FFT A;  3X2N A;  4JJO A;  3SUM A;  2R93 A;  2NYA A;  2BH0 A;  2B63 A;  1QCS A;  4CS0 A;  4AZD A;  2Y0S A;  2NAP A;  4GA6 A;  1AA6 A;  1SIW A;  2IV2 X;  1Y1V A;  1HD5 A;  1E32 A;  4NOH A;  4ENG A;  1E60 A;  4KOD A;  4FG2 A;  2PIC A;  1FDO A;  3CF2 A;  2BE5 D;  1UHE A;  1PT1 A;  1ZC1 A;  3X2L A;  4L48 A;  1PT0 A;  5H4U A;  3PLX B;  1TWH A;  2A68 D;  2R7Z A;  2EEO B;  1H0H A;  1TWF A;  1PQE A;  1N10 A;  2JIO A;  2JIQ A;  2PJJ A;  4CRZ A;  1KQG A;  3SUK A;  3GTM A;  1Y5I A;  1OA9 A;  1L8F A;  2JIM A;  3QWZ A;  3X2O A;  2YUJ A;  3X2H A;  4DMR A;  2WB1 A;  1R7R A;  4JP7 A;  3D30 A;  1KQF A;  4QIW A;  4RV0 A;  3GTP A;  1FDI A;  5GLF A;  2VPY A;  1WC2 A;  1H5N A;  2JA6 A;  5FTJ A;  4KLN A;  1TMO A;  3ML1 A;  3DMR A;  5FTM A;  1PQH A;  3GTO A;  1G8K A;  1OA7 A;  3IR5 A;  3TM7 B;  4GA5 A;  4KO8 A;  5FTK A;  4JP6 A;  4CRY G;  3SUL A;  1E5V A;  1YNJ D;  3CZB A;  2AE0 X;  3IR6 A;  1IW7 D;  1TWC A;  4AYB A;  3IR7 A;  2E2I A;  2HCZ X;  5DYG A;  4AAY A;  5GLY A;  4ZM7 A;  1YLE A;  1Y1W A;  1BW4 A;  3OUG A;  5B6C A;  3X2P A;  4D7Z B;  1R27 A;  1SMY D;  1PPY A;  2YU9 A;  1QDN A;  2DMR A;  1AW8 B;  2ENG A;  4AON B;  1VC3 B;  1Y4Z A;  2WAQ A;  5T5I D;  1K83 A;  2NVY A;  1DMR A;  5EPP A;  3CQZ A;  1PYQ A;  3GTL A;  3GTG A;  2E2H A;  2JIP A;  2VPX A;  1UHD A;  2C45 A;  2GAE A;  3X2M A;  3O5A A;  5C18 A;  1R9T A;  5FTN A;  2PJH B;  4FG4 A;  2NVX A;  1E18 A;  2VPW A;  1EU1 A;  4JS7 A;  1WLF A;  3X2K A;  3HKZ A;  1S3S A;  1Q16 A;  1YNN D;  3HU3 A;  3QC8 A;  5GLX A;  4JCW A;  1E61 A;  1TWG A;  4C2M A;  2A6E D;  2PMZ A;  4AVR A;  2JA7 A;  3QQ7 A;  2E7Z A;  2V3V A;  3HU1 A;  2VPZ A;  3H0G A;  3X2I A;  2PI8 A;  3M3G A;  2VUM A;  1G8J A;  4FER A;  2KQA A;  2KI8 A;  1CZ4 A;  1WCM A;  1PYU B;  1PQF A;  1BW3 A;  1OGY A;  2O5J D;  5T5M D;  5DYI A;  2A6H D;  4AOK B; 
#chains in the Genus database with same CATH homology
 3TIW A;  5C1B A;  3QQ8 A;  2JA5 A;  1SFO A;  1I50 A;  2R92 A;  3GTQ A;  1CZ5 A;  4KDL A;  1I3Q A;  1CR5 A;  1TWA A;  2V45 A;  1ZYR D;  2A69 D;  3FKI A;  2G6G A;  3GTK A;  2PNW A;  1DMS A;  4KDI A;  5FTL A;  3GTJ A;  2G5D A;  2JIR A;  3HU2 A;  2CW0 D;  2R93 A;  2NYA A;  2B63 A;  1QCS A;  4CS0 A;  4AZD A;  2Y0S A;  2NAP A;  4GA6 A;  1AA6 A;  1SIW A;  2IV2 X;  1Y1V A;  1E32 A;  4NOH A;  1E60 A;  4KOD A;  2PIC A;  1FDO A;  3CF2 A;  2BE5 D;  1UHE A;  1PT1 A;  1ZC1 A;  1PT0 A;  3PLX B;  1TWH A;  2A68 D;  2R7Z A;  2EEO B;  1H0H A;  1TWF A;  1PQE A;  2JIO A;  2JIQ A;  2PJJ A;  4CRZ A;  1KQG A;  3GTM A;  1Y5I A;  2JIM A;  3QWZ A;  2YUJ A;  4DMR A;  2WB1 A;  1R7R A;  1KQF A;  4QIW A;  4RV0 A;  3GTP A;  1FDI A;  5GLF A;  2VPY A;  1H5N A;  2JA6 A;  5FTJ A;  4KLN A;  1TMO A;  3ML1 A;  3DMR A;  5FTM A;  1PQH A;  3GTO A;  1G8K A;  3IR5 A;  3TM7 B;  4GA5 A;  4KO8 A;  5FTK A;  4CRY G;  1E5V A;  1YNJ D;  3CZB A;  2AE0 X;  3IR6 A;  1IW7 D;  1TWC A;  4AYB A;  3IR7 A;  2E2I A;  5DYG A;  4AAY A;  1YLE A;  1Y1W A;  3OUG A;  5B6C A;  4D7Z B;  1R27 A;  1SMY D;  1PPY A;  2YU9 A;  1QDN A;  2DMR A;  1AW8 B;  4AON B;  1VC3 B;  1Y4Z A;  2WAQ A;  5T5I D;  1K83 A;  2NVY A;  1DMR A;  5EPP A;  3CQZ A;  1PYQ A;  3GTL A;  3GTG A;  2E2H A;  2JIP A;  2VPX A;  1UHD A;  2C45 A;  2GAE A;  3O5A A;  5C18 A;  1R9T A;  5FTN A;  2PJH B;  2NVX A;  1E18 A;  2VPW A;  1EU1 A;  1WLF A;  3HKZ A;  1S3S A;  1Q16 A;  1YNN D;  3HU3 A;  3QC8 A;  1E61 A;  1TWG A;  4C2M A;  2A6E D;  2PMZ A;  2JA7 A;  3QQ7 A;  2E7Z A;  2V3V A;  3HU1 A;  2VPZ A;  3H0G A;  2PI8 A;  2VUM A;  1G8J A;  2KI8 A;  1CZ4 A;  1WCM A;  1PYU B;  1PQF A;  1OGY A;  2O5J D;  5T5M D;  5DYI A;  2A6H D;  4AOK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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