2D1JB

Factor xa in complex with the inhibitor 2-[[4-[(5-chloroindol-2-yl)sulfonyl]piperazin-1-yl] carbonyl]thieno[3,2-b]pyridine n-oxide
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
54
structure length
54
Chain Sequence
TRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Coagulation factor X, heavy chain
total genus 12
structure length 54
sequence length 54
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2005-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2d1jB00
4CUEA 2PHBB 4XBMA 4X8SL 4YT6L 1TLEA 2FD6A 5F19A 1EMOA 4X8VL 3TH3L 2F9BL 4A7IA 2WPHE 1WHEA 2W26B 2J4IB 2EI7B 1NFUB 3M37L 4BDXA 5K0HB 1KLJL 3IITB 4XL1A 1HJ7A 2WFXB 1FAKL 3U7UG 3NT1A 4JZEL 2YGOA 1EPGA 3LN0A 2FLBL 2Y80B 1CVUA 1NZIA 1G2LB 2VWMK 4LMFA 3FCSB 2BZ6L 1GK5A 4YT7L 1JV2B 2UWPB 2Q1JB 3GCWE 1MQ5L 1XKBA 3ZYIB 2NPRA 3HS5A 1PGEA 4COXA 3LN1A 1DVAL 1UZPA 4M10A 1IQJL 1HCGB 3QMOA 4CUDA 1ATAA 1V3XB 1P0SL 3K9XA 2XBWL 3M36L 4G1MB 1FF7A 2P16L 3HS7A 1CQEA 3P5BL 3KL6B 4JZDL 1ATBA 5IKVA 2Y7XB 1KSNB 1DIYA 1IQLL 1HT5A 3N8VA 1JL9A 2MGPA 1IGXA 3Q7DA 1APOA 1P9JA 3HPTA 1W8BL 3KK6A 3FBYA 4BTTA 3FFGL 3LTFB 1W7XL 5EGMB 4Y7AB 1HT8A 4RRZA 4ZAEB 2PUQL 4JYVL 1OB1C 2Y7ZB 2J94B 4BXSA 3RR3A 2WG4B 1NFYB 1EMNA 1WU1B 1PRHA 5CKQA 1Q4GA 4MMZB 4TGFA 4RRYA 1IGZA 1DQBA 2WPLE 4YZUB 1IQIL 2P93L 1IJQA 5L2ZL 5L30L 1ZAQA 1IVOC 1IQKL 1HREA 2OYUP 5FDQA 2W3IB 3GCXE 2KV4A 3NJPC 4ZHAB 1UZQA 1G2MB 3HO3A 3ENSA 2W86A 5JVZA 2Y5HL 4AQTA 4Z6AL 2PR3B 3CS7L 3KRKA 2WYJB 2OYEP 1EPIA 1N7DA 2WFTA 3N8YB 4ZH8B 5COXA 1IP0A 3C9AC 1YGCL 1JBUL 3V64C 1NPEB 4M11A 4CUFA 5JBBE 2EI6B 4BTUA 4NA9L 3V65B 2H9EL 2ADXA 3KQDL 2XBVL 3N8YA 5IKRA 3H5CB 5F1AA 2YGPA 2EI8B 5JVYA 3BT2A 2VWLL 4D90A 2J95B 4Y7BB 2RNLA 1U8CB 3SOQA 1G1SA 3HO4A 3DEMA 1ADXA 4OTJA 3SOBB 1YUGA 3TK5B 6COXA 1FE2A 1M1XB 2I9AA 3KQBL 2WYGB 2W3KB 1PFXL 3ASIA 1SZBA 1IOXA 2W2QE 1QFKL 3GISX 3ZYJB 1IQML 4RRWA 1NFWB 1URKA 2BOHA 3ELAL 1N1IA 1AUTL 2XC4L 2P95L 3N8XA 3CFWA 2KB9A 5JBCE 2W2PE 2Y81B 1EGFA 2J38B 2UWOB 3SOVA 2FLRL 2MHPA 5JBAE 5CISA 4BTIA 2WG3C 4CSYA 1CX2A 1IQNL 1PXXA 2DDUA 2J34B 1DDXA 2UWLB 1LPGA 1XKAL 1C5MF 1KLOA 4PH9A 1B9WA 5L2YL 1ATDA 3TGFA 1UZJA 2K2SB 3QH0A 1FFMA 1EBVA 2P26A 1L5GB 1HX2A 2W2NE 1BF9A 1XFEA 1FSBA 1J9CL 4D0EA 2P3FL 1Z6EL 4X8TL 1HZ8A 4Z0KB 2P3UA 4OTYA 2P94L 3OLUA 4O02B 1NQLB 3QCWA 1YO8A 3U73A 2I9BA 1RFNB 3HO5A 1MQ6L 2GD4A 3BT1A 2WPME 2BO2A 5I46L 3LAQA 1UZKA 1CEJA 2BOUA 1WHFA 1COUA 1DX5I 1TOZA 2XC0L 1F0RB 3N8ZA 1EQHA 1FAXL 2WPIE 1LPZA 3KQCL 2W2OE 2BQ6A 2FLGA 4Y79B 4JZFL 1F0SB 3OLTA 1EPHA 2W2ME 1NFXB 4JYUL 4E1GA 5IKTA 1HAEA 1EPJA 3EGFA 5JW1A 1X7AL 3NTGA 5CKNA 1K36A 4X8UL 3MQEA 3POYA 4NGAL 2XBYL 2VVVL 2MGRA 1LQDA 2CJIB 3CA7A 4XLWA 3R05A 2WPJE 3N8WB 4BDWA 3KQEL 3TK6B 2BOKL 2J2UB 1KIGL 1HAFA 2VH0B 2P3TA 1FJSL 3BPSE 1F7MA 2Y5FL 3PGHA 3F6UL 2BMGA 3N8WA 5JB8E 2Y38A 1YUFA 1IOEL 4FM5A 4Y76B 4C16A 2D1JB 1PTHA 1CCVA 1NT0A 3LC5B 3IJEB 1G1QA 2JKHL 2AYLA 1ATEA 2VH6B 4NG9L 3LIWB 1IQGL 1O5DL 2P3FN 4ISHL 2RA0L 4MMYB 3NTBA 4ZXXL 3TBDA 4D0FA 5JB9E 3TZIA 1L3YA 1YUKB 5IKQA 1CCFA 2P28B 2TGFA 2FZZL 2WPKE 5KIRA 1APQA 4LORA 3LC3B 2K2TA 4Z0LA 1LPKA 4O1ZA 2BQ7A 1F7EA 1XDTR 1IQEL 1G1TA 1G1RA 4Y6DB 2Y5GL 1A3PA 2XC5L 2G00L 1KLIL 2KL7A 1LMJA 2M74A 1MOXC 2VJ3A 1IQHL 4ZXYL 3ZYGA 4Y71B 1EAIC 2BQWA 1EZQB 2VVCK 3SW2A 1HRFA 5KN5C 3MDLA 1I0UA 3CENL 4MMXB 4RUTA 3HS6A 2VWOL 3LTGD 1U67A 3Q3KB 2Y82B 2BOXA 2XBXL 3F1SB 5CKMA 1IQFL 1CVWL 2VVUL 4BXWA 1Z6CA 1TPGA 1EQGA 4RRXA 2VWNL 4ISIL 2RHPA 1K37A 3KCGL 4RS0A 2B7DL 5E8DA
chains in the Genus database with same CATH superfamily
4CUEA 2PHBB 4XBMA 4X8SL 4YT6L 1TLEA 2FD6A 5F19A 1EMOA 4X8VL 3TH3L 2F9BL 4A7IA 2WPHE 1WHEA 2W26B 2J4IB 2EI7B 1LK9A 1NFUB 3M37L 4BDXA 5K0HB 1KLJL 3IITB 4XL1A 1HJ7A 2WFXB 1FAKL 3U7UG 3NT1A 4JZEL 2YGOA 1EPGA 3LN0A 2FLBL 2Y80B 1CVUA 1NZIA 1G2LB 2VWMK 4LMFA 3FCSB 2BZ6L 1GK5A 4YT7L 1JV2B 2UWPB 2Q1JB 3GCWE 1MQ5L 1XKBA 3ZYIB 2NPRA 3HS5A 1PGEA 4COXA 3LN1A 1DVAL 1UZPA 4M10A 1IQJL 1HCGB 3QMOA 4CUDA 1ATAA 1V3XB 1P0SL 3K9XA 2XBWL 3M36L 4G1MB 1FF7A 2P16L 3HS7A 1CQEA 3P5BL 3KL6B 4JZDL 1ATBA 5IKVA 2Y7XB 1KSNB 1DIYA 1IQLL 1HT5A 3N8VA 1JL9A 2MGPA 1IGXA 3Q7DA 1APOA 1P9JA 3HPTA 1W8BL 3KK6A 3FBYA 4BTTA 3FFGL 3LTFB 1W7XL 5EGMB 4Y7AB 1HT8A 4RRZA 4ZAEB 2PUQL 4JYVL 1OB1C 2Y7ZB 2J94B 4BXSA 3RR3A 2WG4B 1NFYB 1EMNA 1WU1B 1PRHA 5CKQA 1Q4GA 4MMZB 4TGFA 2JJLA 4RRYA 1IGZA 1DQBA 2WPLE 4YZUB 1IQIL 2P93L 1IJQA 5L2ZL 5L30L 1ZAQA 1IVOC 1IQKL 1HREA 2OYUP 5FDQA 2W3IB 3GCXE 2KV4A 3NJPC 4ZHAB 1UZQA 1G2MB 3HO3A 3ENSA 2W86A 5JVZA 2Y5HL 4AQTA 4Z6AL 2PR3B 3CS7L 3KRKA 2WYJB 2OYEP 1EPIA 1N7DA 2WFTA 3N8YB 4ZH8B 5COXA 1IP0A 3C9AC 1YGCL 1JBUL 3V64C 1NPEB 4M11A 4CUFA 5JBBE 2EI6B 4BTUA 1KKEA 4NA9L 3V65B 2H9EL 2ADXA 3KQDL 2XBVL 3N8YA 5IKRA 3H5CB 5F1AA 2YGPA 2EI8B 5JVYA 3BT2A 2VWLL 4D90A 2J95B 4Y7BB 2RNLA 1U8CB 3SOQA 1G1SA 3HO4A 2HOXA 3DEMA 1ADXA 4OTJA 3SOBB 1YUGA 3TK5B 6COXA 1FE2A 1M1XB 2I9AA 3KQBL 2WYGB 2W3KB 1PFXL 3ASIA 1SZBA 2VRSA 1IOXA 2W2QE 1QFKL 3GISX 3ZYJB 1IQML 4RRWA 1NFWB 1URKA 2BOHA 3ELAL 1N1IA 1AUTL 2XC4L 2P95L 3N8XA 3CFWA 2KB9A 5JBCE 2W2PE 2Y81B 1EGFA 2J38B 2UWOB 3SOVA 2FLRL 2MHPA 5JBAE 5CISA 4BTIA 2WG3C 4CSYA 1CX2A 1IQNL 1PXXA 2DDUA 2J34B 1DDXA 2UWLB 1LPGA 1XKAL 1C5MF 1KLOA 4PH9A 1B9WA 5L2YL 1ATDA 3TGFA 1UZJA 2K2SB 3QH0A 1FFMA 1EBVA 2P26A 1L5GB 1HX2A 2W2NE 1BF9A 1XFEA 1FSBA 1J9CL 4D0EA 2P3FL 1Z6EL 4X8TL 1HZ8A 4Z0KB 2P3UA 4OTYA 2P94L 3OLUA 4O02B 1NQLB 3QCWA 1YO8A 3U73A 2I9BA 1RFNB 4A94C 3HO5A 1MQ6L 2GD4A 3BT1A 2WPME 2BO2A 5I46L 3LAQA 1UZKA 1CEJA 1V1HA 2BOUA 1WHFA 1COUA 2BSFA 1DX5I 1TOZA 2XC0L 1F0RB 3N8ZA 1EQHA 1FAXL 2WPIE 1LPZA 3KQCL 2W2OE 2BQ6A 2FLGA 4Y79B 4JZFL 1F0SB 3OLTA 1EPHA 2W2ME 1NFXB 4JYUL 4E1GA 5IKTA 1HAEA 1EPJA 3EGFA 5JW1A 1X7AL 3NTGA 5CKNA 1K36A 4X8UL 3MQEA 3POYA 4NGAL 2XBYL 2VVVL 2MGRA 1LQDA 2CJIB 3CA7A 4XLWA 3R05A 2WPJE 3N8WB 4BDWA 3KQEL 3TK6B 2BOKL 2J2UB 1KIGL 1HAFA 2VH0B 2P3TA 1FJSL 3BPSE 1F7MA 2Y5FL 3PGHA 3F6UL 2BMGA 3N8WA 5JB8E 2Y38A 1YUFA 1IOEL 4FM5A 4Y76B 4C16A 2D1JB 3S6XA 1PTHA 1CCVA 1NT0A 3LC5B 3IJEB 1G1QA 2JKHL 2AYLA 1ATEA 2VH6B 4NG9L 3LIWB 1IQGL 1O5DL 2P3FN 4ISHL 2YGQA 2RA0L 4MMYB 3NTBA 4ZXXL 3TBDA 4D0FA 5JB9E 3TZIA 1L3YA 1YUKB 5IKQA 1CCFA 2HORA 2P28B 2TGFA 2FZZL 2WPKE 5KIRA 1APQA 4LORA 3LC3B 2K2TA 4Z0LA 2BT7A 1LPKA 1LMMA 4O1ZA 2BQ7A 1F7EA 1XDTR 1IQEL 1G1TA 1G1RA 4GU3A 2Y5GL 4Y6DB 2XC5L 1A3PA 2G00L 1KLIL 2KL7A 1LMJA 2M74A 1MOXC 2VJ3A 2H9EC 2WZPP 1IQHL 4ZXYL 2BT8A 3ZYGA 4Y71B 1EAIC 2BQWA 1EZQB 2VVCK 3SW2A 2KNIA 1HRFA 5KN5C 3MDLA 1I0UA 3CENL 4MMXB 4RUTA 3HS6A 2VWOL 3LTGD 1U67A 3Q3KB 2Y82B 2BOXA 2XBXL 3F1SB 5CKMA 1IQFL 1CVWL 2VVUL 1V1IA 4BXWA 1QIUA 1Z6CA 1TPGA 1EQGA 4RRXA 2VWNL 4GU4A 4ISIL 2RHPA 1K37A 3KCGL 4RS0A 2B7DL 5E8DA
chains in the Genus database with same CATH topology
4CUEA 2PHBB 4XBMA 4X8SL 4YT6L 1TLEA 2FD6A 5F19A 1EMOA 4X8VL 3TH3L 2F9BL 4A7IA 2WPHE 1WHEA 2W26B 2J4IB 2EI7B 1NFUB 3M37L 4BDXA 5K0HB 1KLJL 3IITB 4XL1A 1HJ7A 2WFXB 1FAKL 3U7UG 3NT1A 4JZEL 2YGOA 1EPGA 3LN0A 2FLBL 2Y80B 1CVUA 1NZIA 1G2LB 2VWMK 4LMFA 3FCSB 2BZ6L 1GK5A 4YT7L 1JV2B 2UWPB 2Q1JB 3GCWE 1MQ5L 1XKBA 3ZYIB 2NPRA 3HS5A 1PGEA 4COXA 3LN1A 1DVAL 1UZPA 4M10A 1IQJL 1HCGB 3QMOA 4CUDA 1ATAA 1V3XB 1P0SL 3K9XA 2XBWL 3M36L 4G1MB 1FF7A 2P16L 3HS7A 1CQEA 3P5BL 3KL6B 4JZDL 1ATBA 5IKVA 2Y7XB 1KSNB 1DIYA 1IQLL 1HT5A 3N8VA 1JL9A 2MGPA 1IGXA 3Q7DA 1APOA 1P9JA 3HPTA 1W8BL 3KK6A 3FBYA 4BTTA 3FFGL 3LTFB 1W7XL 5EGMB 4Y7AB 1HT8A 4RRZA 4ZAEB 2PUQL 4JYVL 1OB1C 2Y7ZB 2J94B 4BXSA 3RR3A 2WG4B 1NFYB 1EMNA 1WU1B 1PRHA 5CKQA 1Q4GA 4MMZB 4TGFA 4RRYA 1IGZA 1DQBA 2WPLE 4YZUB 1IQIL 2P93L 1IJQA 5L2ZL 5L30L 1ZAQA 1IVOC 1IQKL 1HREA 2OYUP 5FDQA 2W3IB 3GCXE 2KV4A 3NJPC 4ZHAB 1UZQA 1G2MB 3HO3A 3ENSA 2W86A 5JVZA 2Y5HL 4AQTA 4Z6AL 2PR3B 3CS7L 3KRKA 2WYJB 2OYEP 1EPIA 1N7DA 2WFTA 3N8YB 4ZH8B 5COXA 1IP0A 3C9AC 1YGCL 1JBUL 3V64C 1NPEB 4M11A 4CUFA 5JBBE 2EI6B 4BTUA 4NA9L 3V65B 2H9EL 2ADXA 3KQDL 2XBVL 3N8YA 5IKRA 3H5CB 5F1AA 2YGPA 2EI8B 5JVYA 3BT2A 2VWLL 4D90A 2J95B 4Y7BB 2RNLA 1U8CB 3SOQA 1G1SA 3HO4A 3DEMA 1ADXA 4OTJA 3SOBB 1YUGA 3TK5B 6COXA 1FE2A 1M1XB 2I9AA 3KQBL 2WYGB 2W3KB 1PFXL 3ASIA 1SZBA 1IOXA 2W2QE 1QFKL 3GISX 3ZYJB 1IQML 4RRWA 1NFWB 1URKA 2BOHA 3ELAL 1N1IA 1AUTL 2XC4L 2P95L 3N8XA 3CFWA 2KB9A 5JBCE 2W2PE 2Y81B 1EGFA 2J38B 2UWOB 3SOVA 2FLRL 2MHPA 5JBAE 5CISA 4BTIA 2WG3C 4CSYA 1CX2A 1IQNL 1PXXA 2DDUA 2J34B 1DDXA 2UWLB 1LPGA 1XKAL 1C5MF 1KLOA 4PH9A 1B9WA 5L2YL 1ATDA 3TGFA 1UZJA 2K2SB 3QH0A 1FFMA 1EBVA 2P26A 1L5GB 1HX2A 2W2NE 1BF9A 1XFEA 1FSBA 1J9CL 4D0EA 2P3FL 1Z6EL 4X8TL 1HZ8A 4Z0KB 2P3UA 4OTYA 2P94L 3OLUA 4O02B 1NQLB 3QCWA 1YO8A 3U73A 2I9BA 1RFNB 4A94C 3HO5A 1MQ6L 2GD4A 3BT1A 2WPME 2BO2A 5I46L 3LAQA 1UZKA 1CEJA 2BOUA 1WHFA 1COUA 1DX5I 1TOZA 2XC0L 1F0RB 3N8ZA 1EQHA 1FAXL 2WPIE 1LPZA 3KQCL 2W2OE 2BQ6A 2FLGA 4Y79B 4JZFL 1F0SB 3OLTA 1EPHA 2W2ME 1NFXB 4JYUL 4E1GA 5IKTA 1HAEA 1EPJA 3EGFA 5JW1A 1X7AL 3NTGA 5CKNA 1K36A 4X8UL 3MQEA 3POYA 4NGAL 2XBYL 2VVVL 2MGRA 1LQDA 2CJIB 3CA7A 4XLWA 3R05A 2WPJE 3N8WB 4BDWA 3KQEL 3TK6B 2BOKL 2J2UB 1KIGL 1HAFA 2VH0B 2P3TA 1FJSL 3BPSE 1F7MA 2Y5FL 3PGHA 3F6UL 2BMGA 3N8WA 5JB8E 2Y38A 1YUFA 1IOEL 4FM5A 4Y76B 4C16A 2D1JB 3S6XA 1PTHA 1CCVA 1NT0A 3LC5B 3IJEB 1G1QA 2JKHL 2AYLA 1ATEA 2VH6B 4NG9L 3LIWB 1IQGL 1O5DL 2P3FN 4ISHL 2YGQA 2RA0L 4MMYB 3NTBA 4ZXXL 3TBDA 4D0FA 5JB9E 3TZIA 1L3YA 1YUKB 5IKQA 1CCFA 2P28B 2TGFA 2FZZL 2WPKE 5KIRA 1APQA 4LORA 3LC3B 2K2TA 4Z0LA 1LPKA 1LMMA 4O1ZA 2BQ7A 1F7EA 1XDTR 1IQEL 1G1TA 1G1RA 4Y6DB 2Y5GL 1A3PA 2XC5L 2G00L 1KLIL 2KL7A 1LMJA 2M74A 1MOXC 2VJ3A 2H9EC 2WZPP 1IQHL 4ZXYL 3ZYGA 4Y71B 1EAIC 2BQWA 1EZQB 2VVCK 3SW2A 2KNIA 1HRFA 5KN5C 3MDLA 1I0UA 3CENL 4MMXB 4RUTA 3HS6A 2VWOL 3LTGD 1U67A 3Q3KB 2Y82B 2BOXA 2XBXL 3F1SB 5CKMA 1IQFL 1CVWL 2VVUL 4BXWA 1Z6CA 1TPGA 1EQGA 4RRXA 2VWNL 4ISIL 2RHPA 1K37A 3KCGL 4RS0A 2B7DL 5E8DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CUE A;  2PHB B;  4XBM A;  4X8S L;  4YT6 L;  1TLE A;  2FD6 A;  5F19 A;  1EMO A;  4X8V L;  3TH3 L;  2F9B L;  4A7I A;  2WPH E;  1WHE A;  2W26 B;  2J4I B;  2EI7 B;  1NFU B;  3M37 L;  4BDX A;  5K0H B;  1KLJ L;  3IIT B;  4XL1 A;  1HJ7 A;  2WFX B;  1FAK L;  3U7U G;  3NT1 A;  4JZE L;  2YGO A;  1EPG A;  3LN0 A;  2FLB L;  2Y80 B;  1CVU A;  1NZI A;  1G2L B;  2VWM K;  4LMF A;  3FCS B;  2BZ6 L;  1GK5 A;  4YT7 L;  1JV2 B;  2UWP B;  2Q1J B;  3GCW E;  1MQ5 L;  1XKB A;  3ZYI B;  2NPR A;  3HS5 A;  1PGE A;  4COX A;  3LN1 A;  1DVA L;  1UZP A;  4M10 A;  1IQJ L;  1HCG B;  3QMO A;  4CUD A;  1ATA A;  1V3X B;  1P0S L;  3K9X A;  2XBW L;  3M36 L;  4G1M B;  1FF7 A;  2P16 L;  3HS7 A;  1CQE A;  3P5B L;  3KL6 B;  4JZD L;  1ATB A;  5IKV A;  2Y7X B;  1KSN B;  1DIY A;  1IQL L;  1HT5 A;  3N8V A;  1JL9 A;  2MGP A;  1IGX A;  3Q7D A;  1APO A;  1P9J A;  3HPT A;  1W8B L;  3KK6 A;  3FBY A;  4BTT A;  3FFG L;  3LTF B;  1W7X L;  5EGM B;  4Y7A B;  1HT8 A;  4RRZ A;  4ZAE B;  2PUQ L;  4JYV L;  1OB1 C;  2Y7Z B;  2J94 B;  4BXS A;  3RR3 A;  2WG4 B;  1NFY B;  1EMN A;  1WU1 B;  1PRH A;  5CKQ A;  1Q4G A;  4MMZ B;  4TGF A;  4RRY A;  1IGZ A;  1DQB A;  2WPL E;  4YZU B;  1IQI L;  2P93 L;  1IJQ A;  5L2Z L;  5L30 L;  1ZAQ A;  1IVO C;  1IQK L;  1HRE A;  2OYU P;  5FDQ A;  2W3I B;  3GCX E;  2KV4 A;  3NJP C;  4ZHA B;  1UZQ A;  1G2M B;  3HO3 A;  3ENS A;  2W86 A;  5JVZ A;  2Y5H L;  4AQT A;  4Z6A L;  2PR3 B;  3CS7 L;  3KRK A;  2WYJ B;  2OYE P;  1EPI A;  1N7D A;  2WFT A;  3N8Y B;  4ZH8 B;  5COX A;  1IP0 A;  3C9A C;  1YGC L;  1JBU L;  3V64 C;  1NPE B;  4M11 A;  4CUF A;  5JBB E;  2EI6 B;  4BTU A;  4NA9 L;  3V65 B;  2H9E L;  2ADX A;  3KQD L;  2XBV L;  3N8Y A;  5IKR A;  3H5C B;  5F1A A;  2YGP A;  2EI8 B;  5JVY A;  3BT2 A;  2VWL L;  4D90 A;  2J95 B;  4Y7B B;  2RNL A;  1U8C B;  3SOQ A;  1G1S A;  3HO4 A;  3DEM A;  1ADX A;  4OTJ A;  3SOB B;  1YUG A;  3TK5 B;  6COX A;  1FE2 A;  1M1X B;  2I9A A;  3KQB L;  2WYG B;  2W3K B;  1PFX L;  3ASI A;  1SZB A;  1IOX A;  2W2Q E;  1QFK L;  3GIS X;  3ZYJ B;  1IQM L;  4RRW A;  1NFW B;  1URK A;  2BOH A;  3ELA L;  1N1I A;  1AUT L;  2XC4 L;  2P95 L;  3N8X A;  3CFW A;  2KB9 A;  5JBC E;  2W2P E;  2Y81 B;  1EGF A;  2J38 B;  2UWO B;  3SOV A;  2FLR L;  2MHP A;  5JBA E;  5CIS A;  4BTI A;  2WG3 C;  4CSY A;  1CX2 A;  1IQN L;  1PXX A;  2DDU A;  2J34 B;  1DDX A;  2UWL B;  1LPG A;  1XKA L;  1C5M F;  1KLO A;  4PH9 A;  1B9W A;  5L2Y L;  1ATD A;  3TGF A;  1UZJ A;  2K2S B;  3QH0 A;  1FFM A;  1EBV A;  2P26 A;  1L5G B;  1HX2 A;  2W2N E;  1BF9 A;  1XFE A;  1FSB A;  1J9C L;  4D0E A;  2P3F L;  1Z6E L;  4X8T L;  1HZ8 A;  4Z0K B;  2P3U A;  4OTY A;  2P94 L;  3OLU A;  4O02 B;  1NQL B;  3QCW A;  1YO8 A;  3U73 A;  2I9B A;  1RFN B;  3HO5 A;  1MQ6 L;  2GD4 A;  3BT1 A;  2WPM E;  2BO2 A;  5I46 L;  3LAQ A;  1UZK A;  1CEJ A;  2BOU A;  1WHF A;  1COU A;  1DX5 I;  1TOZ A;  2XC0 L;  1F0R B;  3N8Z A;  1EQH A;  1FAX L;  2WPI E;  1LPZ A;  3KQC L;  2W2O E;  2BQ6 A;  2FLG A;  4Y79 B;  4JZF L;  1F0S B;  3OLT A;  1EPH A;  2W2M E;  1NFX B;  4JYU L;  4E1G A;  5IKT A;  1HAE A;  1EPJ A;  3EGF A;  5JW1 A;  1X7A L;  3NTG A;  5CKN A;  1K36 A;  4X8U L;  3MQE A;  3POY A;  4NGA L;  2XBY L;  2VVV L;  2MGR A;  1LQD A;  2CJI B;  3CA7 A;  4XLW A;  3R05 A;  2WPJ E;  3N8W B;  4BDW A;  3KQE L;  3TK6 B;  2BOK L;  2J2U B;  1KIG L;  1HAF A;  2VH0 B;  2P3T A;  1FJS L;  3BPS E;  1F7M A;  2Y5F L;  3PGH A;  3F6U L;  2BMG A;  3N8W A;  5JB8 E;  2Y38 A;  1YUF A;  1IOE L;  4FM5 A;  4Y76 B;  4C16 A;  2D1J B;  1PTH A;  1CCV A;  1NT0 A;  3LC5 B;  3IJE B;  1G1Q A;  2JKH L;  2AYL A;  1ATE A;  2VH6 B;  4NG9 L;  3LIW B;  1IQG L;  1O5D L;  2P3F N;  4ISH L;  2RA0 L;  4MMY B;  3NTB A;  4ZXX L;  3TBD A;  4D0F A;  5JB9 E;  3TZI A;  1L3Y A;  1YUK B;  5IKQ A;  1CCF A;  2P28 B;  2TGF A;  2FZZ L;  2WPK E;  5KIR A;  1APQ A;  4LOR A;  3LC3 B;  2K2T A;  4Z0L A;  1LPK A;  4O1Z A;  2BQ7 A;  1F7E A;  1XDT R;  1IQE L;  1G1T A;  1G1R A;  4Y6D B;  2Y5G L;  1A3P A;  2XC5 L;  2G00 L;  1KLI L;  2KL7 A;  1LMJ A;  2M74 A;  1MOX C;  2VJ3 A;  1IQH L;  4ZXY L;  3ZYG A;  4Y71 B;  1EAI C;  2BQW A;  1EZQ B;  2VVC K;  3SW2 A;  1HRF A;  5KN5 C;  3MDL A;  1I0U A;  3CEN L;  4MMX B;  4RUT A;  3HS6 A;  2VWO L;  3LTG D;  1U67 A;  3Q3K B;  2Y82 B;  2BOX A;  2XBX L;  3F1S B;  5CKM A;  1IQF L;  1CVW L;  2VVU L;  4BXW A;  1Z6C A;  1TPG A;  1EQG A;  4RRX A;  2VWN L;  4ISI L;  2RHP A;  1K37 A;  3KCG L;  4RS0 A;  2B7D L;  5E8D A; 
#chains in the Genus database with same CATH topology
 4CUE A;  2PHB B;  4XBM A;  4X8S L;  4YT6 L;  1TLE A;  2FD6 A;  5F19 A;  1EMO A;  4X8V L;  3TH3 L;  2F9B L;  4A7I A;  2WPH E;  1WHE A;  2W26 B;  2J4I B;  2EI7 B;  1LK9 A;  1NFU B;  3M37 L;  4BDX A;  5K0H B;  1KLJ L;  3IIT B;  4XL1 A;  1HJ7 A;  2WFX B;  1FAK L;  3U7U G;  3NT1 A;  4JZE L;  2YGO A;  1EPG A;  3LN0 A;  2FLB L;  2Y80 B;  1CVU A;  1NZI A;  1G2L B;  2VWM K;  4LMF A;  3FCS B;  2BZ6 L;  1GK5 A;  4YT7 L;  1JV2 B;  2UWP B;  2Q1J B;  3GCW E;  1MQ5 L;  1XKB A;  3ZYI B;  2NPR A;  3HS5 A;  1PGE A;  4COX A;  3LN1 A;  1DVA L;  1UZP A;  4M10 A;  1IQJ L;  1HCG B;  3QMO A;  4CUD A;  1ATA A;  1V3X B;  1P0S L;  3K9X A;  2XBW L;  3M36 L;  4G1M B;  1FF7 A;  2P16 L;  3HS7 A;  1CQE A;  3P5B L;  3KL6 B;  4JZD L;  1ATB A;  5IKV A;  2Y7X B;  1KSN B;  1DIY A;  1IQL L;  1HT5 A;  3N8V A;  1JL9 A;  2MGP A;  1IGX A;  3Q7D A;  1APO A;  1P9J A;  3HPT A;  1W8B L;  3KK6 A;  3FBY A;  4BTT A;  3FFG L;  3LTF B;  1W7X L;  5EGM B;  4Y7A B;  1HT8 A;  4RRZ A;  4ZAE B;  2PUQ L;  4JYV L;  1OB1 C;  2Y7Z B;  2J94 B;  4BXS A;  3RR3 A;  2WG4 B;  1NFY B;  1EMN A;  1WU1 B;  1PRH A;  5CKQ A;  1Q4G A;  4MMZ B;  4TGF A;  2JJL A;  4RRY A;  1IGZ A;  1DQB A;  2WPL E;  4YZU B;  1IQI L;  2P93 L;  1IJQ A;  5L2Z L;  5L30 L;  1ZAQ A;  1IVO C;  1IQK L;  1HRE A;  2OYU P;  5FDQ A;  2W3I B;  3GCX E;  2KV4 A;  3NJP C;  4ZHA B;  1UZQ A;  1G2M B;  3HO3 A;  3ENS A;  2W86 A;  5JVZ A;  2Y5H L;  4AQT A;  4Z6A L;  2PR3 B;  3CS7 L;  3KRK A;  2WYJ B;  2OYE P;  1EPI A;  1N7D A;  2WFT A;  3N8Y B;  4ZH8 B;  5COX A;  1IP0 A;  3C9A C;  1YGC L;  1JBU L;  3V64 C;  1NPE B;  4M11 A;  4CUF A;  5JBB E;  2EI6 B;  4BTU A;  1KKE A;  4NA9 L;  3V65 B;  2H9E L;  2ADX A;  3KQD L;  2XBV L;  3N8Y A;  5IKR A;  3H5C B;  5F1A A;  2YGP A;  2EI8 B;  5JVY A;  3BT2 A;  2VWL L;  4D90 A;  2J95 B;  4Y7B B;  2RNL A;  1U8C B;  3SOQ A;  1G1S A;  3HO4 A;  2HOX A;  3DEM A;  1ADX A;  4OTJ A;  3SOB B;  1YUG A;  3TK5 B;  6COX A;  1FE2 A;  1M1X B;  2I9A A;  3KQB L;  2WYG B;  2W3K B;  1PFX L;  3ASI A;  1SZB A;  2VRS A;  1IOX A;  2W2Q E;  1QFK L;  3GIS X;  3ZYJ B;  1IQM L;  4RRW A;  1NFW B;  1URK A;  2BOH A;  3ELA L;  1N1I A;  1AUT L;  2XC4 L;  2P95 L;  3N8X A;  3CFW A;  2KB9 A;  5JBC E;  2W2P E;  2Y81 B;  1EGF A;  2J38 B;  2UWO B;  3SOV A;  2FLR L;  2MHP A;  5JBA E;  5CIS A;  4BTI A;  2WG3 C;  4CSY A;  1CX2 A;  1IQN L;  1PXX A;  2DDU A;  2J34 B;  1DDX A;  2UWL B;  1LPG A;  1XKA L;  1C5M F;  1KLO A;  4PH9 A;  1B9W A;  5L2Y L;  1ATD A;  3TGF A;  1UZJ A;  2K2S B;  3QH0 A;  1FFM A;  1EBV A;  2P26 A;  1L5G B;  1HX2 A;  2W2N E;  1BF9 A;  1XFE A;  1FSB A;  1J9C L;  4D0E A;  2P3F L;  1Z6E L;  4X8T L;  1HZ8 A;  4Z0K B;  2P3U A;  4OTY A;  2P94 L;  3OLU A;  4O02 B;  1NQL B;  3QCW A;  1YO8 A;  3U73 A;  2I9B A;  1RFN B;  4A94 C;  3HO5 A;  1MQ6 L;  2GD4 A;  3BT1 A;  2WPM E;  2BO2 A;  5I46 L;  3LAQ A;  1UZK A;  1CEJ A;  1V1H A;  2BOU A;  1WHF A;  1COU A;  2BSF A;  1DX5 I;  1TOZ A;  2XC0 L;  1F0R B;  3N8Z A;  1EQH A;  1FAX L;  2WPI E;  1LPZ A;  3KQC L;  2W2O E;  2BQ6 A;  2FLG A;  4Y79 B;  4JZF L;  1F0S B;  3OLT A;  1EPH A;  2W2M E;  1NFX B;  4JYU L;  4E1G A;  5IKT A;  1HAE A;  1EPJ A;  3EGF A;  5JW1 A;  1X7A L;  3NTG A;  5CKN A;  1K36 A;  4X8U L;  3MQE A;  3POY A;  4NGA L;  2XBY L;  2VVV L;  2MGR A;  1LQD A;  2CJI B;  3CA7 A;  4XLW A;  3R05 A;  2WPJ E;  3N8W B;  4BDW A;  3KQE L;  3TK6 B;  2BOK L;  2J2U B;  1KIG L;  1HAF A;  2VH0 B;  2P3T A;  1FJS L;  3BPS E;  1F7M A;  2Y5F L;  3PGH A;  3F6U L;  2BMG A;  3N8W A;  5JB8 E;  2Y38 A;  1YUF A;  1IOE L;  4FM5 A;  4Y76 B;  4C16 A;  2D1J B;  3S6X A;  1PTH A;  1CCV A;  1NT0 A;  3LC5 B;  3IJE B;  1G1Q A;  2JKH L;  2AYL A;  1ATE A;  2VH6 B;  4NG9 L;  3LIW B;  1IQG L;  1O5D L;  2P3F N;  4ISH L;  2YGQ A;  2RA0 L;  4MMY B;  3NTB A;  4ZXX L;  3TBD A;  4D0F A;  5JB9 E;  3TZI A;  1L3Y A;  1YUK B;  5IKQ A;  1CCF A;  2HOR A;  2P28 B;  2TGF A;  2FZZ L;  2WPK E;  5KIR A;  1APQ A;  4LOR A;  3LC3 B;  2K2T A;  4Z0L A;  2BT7 A;  1LPK A;  1LMM A;  4O1Z A;  2BQ7 A;  1F7E A;  1XDT R;  1IQE L;  1G1T A;  1G1R A;  4GU3 A;  2Y5G L;  4Y6D B;  2XC5 L;  1A3P A;  2G00 L;  1KLI L;  2KL7 A;  1LMJ A;  2M74 A;  1MOX C;  2VJ3 A;  2H9E C;  2WZP P;  1IQH L;  4ZXY L;  2BT8 A;  3ZYG A;  4Y71 B;  1EAI C;  2BQW A;  1EZQ B;  2VVC K;  3SW2 A;  2KNI A;  1HRF A;  5KN5 C;  3MDL A;  1I0U A;  3CEN L;  4MMX B;  4RUT A;  3HS6 A;  2VWO L;  3LTG D;  1U67 A;  3Q3K B;  2Y82 B;  2BOX A;  2XBX L;  3F1S B;  5CKM A;  1IQF L;  1CVW L;  2VVU L;  1V1I A;  4BXW A;  1QIU A;  1Z6C A;  1TPG A;  1EQG A;  4RRX A;  2VWN L;  4GU4 A;  4ISI L;  2RHP A;  1K37 A;  3KCG L;  4RS0 A;  2B7D L;  5E8D A; 
#chains in the Genus database with same CATH homology
 4CUE A;  2PHB B;  4XBM A;  4X8S L;  4YT6 L;  1TLE A;  2FD6 A;  5F19 A;  1EMO A;  4X8V L;  3TH3 L;  2F9B L;  4A7I A;  2WPH E;  1WHE A;  2W26 B;  2J4I B;  2EI7 B;  1NFU B;  3M37 L;  4BDX A;  5K0H B;  1KLJ L;  3IIT B;  4XL1 A;  1HJ7 A;  2WFX B;  1FAK L;  3U7U G;  3NT1 A;  4JZE L;  2YGO A;  1EPG A;  3LN0 A;  2FLB L;  2Y80 B;  1CVU A;  1NZI A;  1G2L B;  2VWM K;  4LMF A;  3FCS B;  2BZ6 L;  1GK5 A;  4YT7 L;  1JV2 B;  2UWP B;  2Q1J B;  3GCW E;  1MQ5 L;  1XKB A;  3ZYI B;  2NPR A;  3HS5 A;  1PGE A;  4COX A;  3LN1 A;  1DVA L;  1UZP A;  4M10 A;  1IQJ L;  1HCG B;  3QMO A;  4CUD A;  1ATA A;  1V3X B;  1P0S L;  3K9X A;  2XBW L;  3M36 L;  4G1M B;  1FF7 A;  2P16 L;  3HS7 A;  1CQE A;  3P5B L;  3KL6 B;  4JZD L;  1ATB A;  5IKV A;  2Y7X B;  1KSN B;  1DIY A;  1IQL L;  1HT5 A;  3N8V A;  1JL9 A;  2MGP A;  1IGX A;  3Q7D A;  1APO A;  1P9J A;  3HPT A;  1W8B L;  3KK6 A;  3FBY A;  4BTT A;  3FFG L;  3LTF B;  1W7X L;  5EGM B;  4Y7A B;  1HT8 A;  4RRZ A;  4ZAE B;  2PUQ L;  4JYV L;  1OB1 C;  2Y7Z B;  2J94 B;  4BXS A;  3RR3 A;  2WG4 B;  1NFY B;  1EMN A;  1WU1 B;  1PRH A;  5CKQ A;  1Q4G A;  4MMZ B;  4TGF A;  4RRY A;  1IGZ A;  1DQB A;  2WPL E;  4YZU B;  1IQI L;  2P93 L;  1IJQ A;  5L2Z L;  5L30 L;  1ZAQ A;  1IVO C;  1IQK L;  1HRE A;  2OYU P;  5FDQ A;  2W3I B;  3GCX E;  2KV4 A;  3NJP C;  4ZHA B;  1UZQ A;  1G2M B;  3HO3 A;  3ENS A;  2W86 A;  5JVZ A;  2Y5H L;  4AQT A;  4Z6A L;  2PR3 B;  3CS7 L;  3KRK A;  2WYJ B;  2OYE P;  1EPI A;  1N7D A;  2WFT A;  3N8Y B;  4ZH8 B;  5COX A;  1IP0 A;  3C9A C;  1YGC L;  1JBU L;  3V64 C;  1NPE B;  4M11 A;  4CUF A;  5JBB E;  2EI6 B;  4BTU A;  4NA9 L;  3V65 B;  2H9E L;  2ADX A;  3KQD L;  2XBV L;  3N8Y A;  5IKR A;  3H5C B;  5F1A A;  2YGP A;  2EI8 B;  5JVY A;  3BT2 A;  2VWL L;  4D90 A;  2J95 B;  4Y7B B;  2RNL A;  1U8C B;  3SOQ A;  1G1S A;  3HO4 A;  3DEM A;  1ADX A;  4OTJ A;  3SOB B;  1YUG A;  3TK5 B;  6COX A;  1FE2 A;  1M1X B;  2I9A A;  3KQB L;  2WYG B;  2W3K B;  1PFX L;  3ASI A;  1SZB A;  1IOX A;  2W2Q E;  1QFK L;  3GIS X;  3ZYJ B;  1IQM L;  4RRW A;  1NFW B;  1URK A;  2BOH A;  3ELA L;  1N1I A;  1AUT L;  2XC4 L;  2P95 L;  3N8X A;  3CFW A;  2KB9 A;  5JBC E;  2W2P E;  2Y81 B;  1EGF A;  2J38 B;  2UWO B;  3SOV A;  2FLR L;  2MHP A;  5JBA E;  5CIS A;  4BTI A;  2WG3 C;  4CSY A;  1CX2 A;  1IQN L;  1PXX A;  2DDU A;  2J34 B;  1DDX A;  2UWL B;  1LPG A;  1XKA L;  1C5M F;  1KLO A;  4PH9 A;  1B9W A;  5L2Y L;  1ATD A;  3TGF A;  1UZJ A;  2K2S B;  3QH0 A;  1FFM A;  1EBV A;  2P26 A;  1L5G B;  1HX2 A;  2W2N E;  1BF9 A;  1XFE A;  1FSB A;  1J9C L;  4D0E A;  2P3F L;  1Z6E L;  4X8T L;  1HZ8 A;  4Z0K B;  2P3U A;  4OTY A;  2P94 L;  3OLU A;  4O02 B;  1NQL B;  3QCW A;  1YO8 A;  3U73 A;  2I9B A;  1RFN B;  4A94 C;  3HO5 A;  1MQ6 L;  2GD4 A;  3BT1 A;  2WPM E;  2BO2 A;  5I46 L;  3LAQ A;  1UZK A;  1CEJ A;  2BOU A;  1WHF A;  1COU A;  1DX5 I;  1TOZ A;  2XC0 L;  1F0R B;  3N8Z A;  1EQH A;  1FAX L;  2WPI E;  1LPZ A;  3KQC L;  2W2O E;  2BQ6 A;  2FLG A;  4Y79 B;  4JZF L;  1F0S B;  3OLT A;  1EPH A;  2W2M E;  1NFX B;  4JYU L;  4E1G A;  5IKT A;  1HAE A;  1EPJ A;  3EGF A;  5JW1 A;  1X7A L;  3NTG A;  5CKN A;  1K36 A;  4X8U L;  3MQE A;  3POY A;  4NGA L;  2XBY L;  2VVV L;  2MGR A;  1LQD A;  2CJI B;  3CA7 A;  4XLW A;  3R05 A;  2WPJ E;  3N8W B;  4BDW A;  3KQE L;  3TK6 B;  2BOK L;  2J2U B;  1KIG L;  1HAF A;  2VH0 B;  2P3T A;  1FJS L;  3BPS E;  1F7M A;  2Y5F L;  3PGH A;  3F6U L;  2BMG A;  3N8W A;  5JB8 E;  2Y38 A;  1YUF A;  1IOE L;  4FM5 A;  4Y76 B;  4C16 A;  2D1J B;  3S6X A;  1PTH A;  1CCV A;  1NT0 A;  3LC5 B;  3IJE B;  1G1Q A;  2JKH L;  2AYL A;  1ATE A;  2VH6 B;  4NG9 L;  3LIW B;  1IQG L;  1O5D L;  2P3F N;  4ISH L;  2YGQ A;  2RA0 L;  4MMY B;  3NTB A;  4ZXX L;  3TBD A;  4D0F A;  5JB9 E;  3TZI A;  1L3Y A;  1YUK B;  5IKQ A;  1CCF A;  2P28 B;  2TGF A;  2FZZ L;  2WPK E;  5KIR A;  1APQ A;  4LOR A;  3LC3 B;  2K2T A;  4Z0L A;  1LPK A;  1LMM A;  4O1Z A;  2BQ7 A;  1F7E A;  1XDT R;  1IQE L;  1G1T A;  1G1R A;  4Y6D B;  2Y5G L;  1A3P A;  2XC5 L;  2G00 L;  1KLI L;  2KL7 A;  1LMJ A;  2M74 A;  1MOX C;  2VJ3 A;  2H9E C;  2WZP P;  1IQH L;  4ZXY L;  3ZYG A;  4Y71 B;  1EAI C;  2BQW A;  1EZQ B;  2VVC K;  3SW2 A;  2KNI A;  1HRF A;  5KN5 C;  3MDL A;  1I0U A;  3CEN L;  4MMX B;  4RUT A;  3HS6 A;  2VWO L;  3LTG D;  1U67 A;  3Q3K B;  2Y82 B;  2BOX A;  2XBX L;  3F1S B;  5CKM A;  1IQF L;  1CVW L;  2VVU L;  4BXW A;  1Z6C A;  1TPG A;  1EQG A;  4RRX A;  2VWN L;  4ISI L;  2RHP A;  1K37 A;  3KCG L;  4RS0 A;  2B7D L;  5E8D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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