2F9BL

Discovery of novel heterocyclic factor viia inhibitors
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
94
structure length
94
Chain Sequence
QCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of novel heterocyclic factor VIIa inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/blood clotting
source organism Homo sapiens
molecule keywords Coagulation factor VII
total genus 18
structure length 94
sequence length 94
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2005-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF00008 EGF EGF-like domain
L PF00594 Gla Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2f9bL02
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2f9bL01
4M11A 1DX5I 5JVYA 1IQNL 3HO4A 1DDXA 5JW1A 1LPKA 3HS7A 3KQEL 2W2OE 4MMYB 2Y80B 3GCWE 3LIWB 1N7DA 2FLGA 2P3TA 1KSNB 1HZ8A 2P94L 3LTFB 2BQ7A 4COXA 4X8VL 5JVZA 4ZH8B 2RHPA 1KIGL 1G1TA 3LTGD 5JB9E 4YT6L 1XKBA 4X8TL 1EMOA 5L2YL 2PHBB 2K2TA 4AQTA 3PGHA 5EGMB 6COXA 4LMFA 2VJ3A 2WFTA 5IKRA 1LMJA 1FAKL 1HJ7A 4ZAEB 4X8SL 2XC4L 3KK6A 2J34B 1PFXL 2Y7ZB 4MMZB 3KQCL 1WHFA 1G1SA 1O5DL 1Z6EL 2WPJE 4Y71B 2Y38A 1J9CL 1ADXA 2BOKL 1DQBA 2P16L 1NPEB 2WPLE 2YGPA 3HS5A 1FF7A 2J94B 4BDWA 2Y7XB 4MMXB 2VH0B 1MOXC 5FDQA 2J4IB 1HT5A 3KQDL 2K2SB 3GCXE 5L2ZL 1Z6CA 2KL7A 4YT7L 4BTIA 3HO5A 3POYA 2MHPA 2BOHA 2W3KB 1UZQA 1F0RB 3GISX 3V64C 4TGFA 3N8YB 1HREA 2WG4B 5IKQA 2YGOA 2RA0L 1EGFA 2W2NE 4O1ZA 4ISIL 1CVUA 4XLWA 4A7IA 3ELAL 3EGFA 5IKTA 3IITB 1IQKL 2WG3C 4NG9L 1PGEA 2BQ6A 3N8WA 1URKA 3SW2A 1K36A 1CVWL 5CKQA 4JZFL 2MGRA 2Y5FL 1ATAA 1ZAQA 1JL9A 2GD4A 4Z0LA 3LAQA 2XC0L 3CENL 1U67A 3TGFA 5IKVA 3CS7L 5F19A 1PXXA 1MQ5L 4Y7AB 3SOVA 2RNLA 1HCGB 5CKNA 1LPZA 3BT2A 1G2MB 3NJPC 1Q4GA 1IOXA 1TOZA 2WPME 3KL6B 1L5GB 1G2LB 3LN0A 4CUFA 3ASIA 3KCGL 1EPIA 1V3XB 2XBVL 2W3IB 2W26B 4LORA 1F0SB 1F7EA 1YGCL 3HO3A 3M36L 1IQJL 1NFWB 1TLEA 1B9WA 1EPGA 4NA9L 1YUGA 2EI8B 2VWLL 4JYUL 3N8WB 2D1JB 3N8YA 2KV4A 1GK5A 4JZDL 3H5CB 1EPHA 2NPRA 2WPHE 1AUTL 2FLBL 3NTBA 3QH0A 3Q3KB 1HT8A 5JB8E 3OLTA 3BPSE 1HAEA 3HS6A 1IGZA 1PTHA 1FSBA 4RRXA 5E8DA 1IQFL 3FCSB 5JBCE 3DEMA 2BOXA 1KLIL 1BF9A 2XBXL 1OB1C 4PH9A 5KIRA 2OYEP 1XFEA 1TPGA 1P9JA 3P5BL 1APOA 1M1XB 1ATBA 1MQ6L 1A3PA 1ATDA 1KLJL 2W2ME 2M74A 4ZXYL 4RRYA 4CUEA 4OTJA 3R05A 1K37A 2P95L 2VVUL 2Q1JB 4D90A 5COXA 3LN1A 1I0UA 1CQEA 1YUKB 3QMOA 4RRWA 4BTUA 2JKHL 3SOBB 1NFUB 5I46L 2VWNL 3N8ZA 3MQEA 1IQGL 2UWOB 5CKMA 3LC5B 3HPTA 4ZXXL 2AYLA 4Y76B 3SOQA 4JYVL 1NT0A 2W86A 1NFYB 2Y5GL 2Y81B 2J38B 2H9EL 1LQDA 1C5MF 3F1SB 1HAFA 1W8BL 2I9BA 4Z0KB 1NZIA 2J2UB 3M37L 3QCWA 1HX2A 1UZKA 3CA7A 4RS0A 2EI6B 2XC5L 5F1AA 4BXWA 3KRKA 4M10A 3IJEB 4E1GA 1CCVA 2UWLB 2B7DL 1IQLL 2Y82B 2CJIB 2ADXA 2FLRL 2WYGB 1IQIL 1CEJA 1YO8A 1F7MA 4JZEL 2BO2A 2J95B 2MGPA 1IJQA 3ZYJB 4FM5A 3RR3A 2OYUP 2VWOL 3NTGA 1EQGA 3V65B 1DIYA 3ENSA 5KN5C 1EPJA 4XBMA 4BTTA 1KLOA 4G1MB 1P0SL 4Z6AL 2VWMK 4D0FA 4RUTA 1JV2B 2VH6B 2VVCK 2P3FN 3F6UL 1WHEA 2W2PE 1DVAL 1UZPA 2WFXB 1SZBA 3TZIA 1IGXA 1CCFA 4ZHAB 1IQHL 1EZQB 3LC3B 3N8XA 2P28B 2XBYL 1PRHA 3MDLA 2PUQL 2FZZL 2WPKE 3U7UG 2W2QE 1NFXB 1QFKL 3Q7DA 2WYJB 4ISHL 1IQML 1JBUL 4BXSA 1CX2A 2F9BL 2VVVL 2TGFA 2P93L 3NT1A 1APQA 3FBYA 2P3UA 1U8CB 1XDTR 4D0EA 4BDXA 2BOUA 5JBAE 3TH3L 2EI7B 3BT1A 1EBVA 3K9XA 2UWPB 5K0HB 1FAXL 1W7XL 1FFMA 4Y7BB 2BMGA 1N1IA 2I9AA 1IOEL 3OLUA 1IP0A 4RRZA 1LPGA 2P3FL 2DDUA 4CUDA 1UZJA 1G1RA 1COUA 4XL1A 2G00L 1HRFA 4CSYA 5L30L 3N8VA 1FJSL 2PR3B 1IQEL 1YUFA 1EMNA 3KQBL 1G1QA 1EQHA 3CFWA 2Y5HL 4C16A 5JBBE 1NQLB 3C9AC 3TK6B 4OTYA 3TBDA 3U73A 1RFNB 1L3YA 4X8UL 4Y79B 3ZYGA 4O02B 1IVOC 1X7AL 3TK5B 5CISA 4YZUB 2FD6A 2P26A 2BQWA 1ATEA 2XBWL 1FE2A 3FFGL 1WU1B 4NGAL 3ZYIB 1XKAL 4Y6DB 2KB9A 2BZ6L 1EAIC 2WPIE
chains in the Genus database with same CATH superfamily
1LMMA 4M11A 1DX5I 5JVYA 1IQNL 3HO4A 1DDXA 5JW1A 1LPKA 3HS7A 3KQEL 2W2OE 4MMYB 4GU4A 2Y80B 3GCWE 3LIWB 1N7DA 2FLGA 2P3TA 1KSNB 1HZ8A 2P94L 3LTFB 2BQ7A 4COXA 4X8VL 5JVZA 4ZH8B 2RHPA 1KIGL 1G1TA 3LTGD 5JB9E 4YT6L 1XKBA 4X8TL 1EMOA 5L2YL 2YGQA 2PHBB 2K2TA 4AQTA 3PGHA 5EGMB 6COXA 4LMFA 2VJ3A 2WFTA 5IKRA 1LMJA 1FAKL 1HJ7A 4ZAEB 4X8SL 2XC4L 3KK6A 2J34B 1PFXL 2Y7ZB 4MMZB 3KQCL 1WHFA 1G1SA 1O5DL 1Z6EL 2WPJE 4Y71B 2Y38A 1J9CL 1ADXA 2BOKL 1DQBA 2P16L 1NPEB 2WPLE 2YGPA 3HS5A 1FF7A 2J94B 4BDWA 2Y7XB 4MMXB 2VH0B 1MOXC 5FDQA 2J4IB 1HT5A 3KQDL 2K2SB 3GCXE 5L2ZL 1Z6CA 2KL7A 4YT7L 4BTIA 3HO5A 3POYA 2MHPA 2BOHA 2W3KB 1UZQA 1F0RB 3GISX 3V64C 4TGFA 3N8YB 1HREA 2WG4B 5IKQA 1LK9A 2YGOA 2RA0L 1EGFA 2W2NE 4O1ZA 4ISIL 1CVUA 4XLWA 4A7IA 3ELAL 3EGFA 1V1HA 5IKTA 3IITB 1IQKL 2WG3C 4NG9L 1PGEA 3S6XA 2BQ6A 3N8WA 1URKA 3SW2A 1K36A 1CVWL 5CKQA 4JZFL 2MGRA 2Y5FL 1ATAA 1ZAQA 1JL9A 2GD4A 4Z0LA 3LAQA 2XC0L 3CENL 1U67A 1KKEA 3TGFA 5IKVA 3CS7L 5F19A 2HOXA 1PXXA 1MQ5L 4Y7AB 3SOVA 2RNLA 1HCGB 5CKNA 1LPZA 3BT2A 1G2MB 3NJPC 1Q4GA 1IOXA 1TOZA 2WPME 3KL6B 2BSFA 1L5GB 1G2LB 3LN0A 4CUFA 3ASIA 3KCGL 1EPIA 1V3XB 2XBVL 2W3IB 2W26B 4LORA 1F0SB 1F7EA 1YGCL 3HO3A 3M36L 1IQJL 1NFWB 1TLEA 1B9WA 1EPGA 4NA9L 1YUGA 2EI8B 2VWLL 4JYUL 3N8WB 2D1JB 3N8YA 2KV4A 1GK5A 4JZDL 3H5CB 1EPHA 2NPRA 2WPHE 1AUTL 2FLBL 3NTBA 3QH0A 3Q3KB 1HT8A 4A94C 5JB8E 3OLTA 3BPSE 1HAEA 3HS6A 1IGZA 1PTHA 1FSBA 4RRXA 5E8DA 1IQFL 3FCSB 5JBCE 3DEMA 2BOXA 1KLIL 1BF9A 2XBXL 1OB1C 4PH9A 5KIRA 2OYEP 1XFEA 1TPGA 1P9JA 3P5BL 1APOA 1M1XB 1ATBA 1MQ6L 1A3PA 1ATDA 1KLJL 2W2ME 2M74A 4ZXYL 4RRYA 4CUEA 4OTJA 3R05A 1K37A 2BT7A 2P95L 2VVUL 2Q1JB 4D90A 5COXA 3LN1A 1I0UA 1CQEA 2WZPP 1YUKB 3QMOA 4RRWA 1QIUA 4BTUA 2JKHL 3SOBB 1NFUB 5I46L 2VWNL 3N8ZA 3MQEA 1IQGL 2UWOB 5CKMA 3LC5B 3HPTA 4ZXXL 2AYLA 4Y76B 3SOQA 4JYVL 1NT0A 2W86A 1NFYB 2Y5GL 2Y81B 2J38B 2H9EL 1LQDA 1C5MF 3F1SB 1HAFA 1W8BL 2HORA 2I9BA 4Z0KB 1NZIA 2J2UB 3M37L 3QCWA 1HX2A 1UZKA 3CA7A 4RS0A 2EI6B 2XC5L 5F1AA 4BXWA 3KRKA 4M10A 3IJEB 4E1GA 1CCVA 2UWLB 2B7DL 1IQLL 2Y82B 2CJIB 2VRSA 2ADXA 2FLRL 2WYGB 1IQIL 1CEJA 1YO8A 1F7MA 2BT8A 2BO2A 4JZEL 2J95B 2MGPA 1IJQA 3ZYJB 4FM5A 3RR3A 2OYUP 2VWOL 3NTGA 1EQGA 3V65B 1DIYA 3ENSA 5KN5C 1EPJA 4XBMA 4BTTA 1KLOA 4G1MB 1P0SL 4Z6AL 2VWMK 4D0FA 4RUTA 1JV2B 2VH6B 2VVCK 2P3FN 3F6UL 1WHEA 2W2PE 1DVAL 1UZPA 2WFXB 1SZBA 3TZIA 1IGXA 1CCFA 4ZHAB 1IQHL 1EZQB 3LC3B 3N8XA 2P28B 2XBYL 1PRHA 3MDLA 2PUQL 2FZZL 2WPKE 2KNIA 3U7UG 2W2QE 1NFXB 1QFKL 2JJLA 3Q7DA 2WYJB 4ISHL 1IQML 1JBUL 4BXSA 1CX2A 2F9BL 2VVVL 2TGFA 2P93L 3NT1A 1APQA 3FBYA 2P3UA 1U8CB 1XDTR 4D0EA 4BDXA 2BOUA 5JBAE 3TH3L 2EI7B 3BT1A 1EBVA 3K9XA 2UWPB 5K0HB 1FAXL 1W7XL 1FFMA 4Y7BB 2BMGA 1N1IA 2I9AA 1IOEL 3OLUA 1IP0A 2H9EC 4RRZA 1LPGA 2P3FL 2DDUA 4CUDA 1UZJA 1G1RA 1COUA 4XL1A 2G00L 1HRFA 4CSYA 5L30L 3N8VA 1FJSL 2PR3B 4GU3A 1IQEL 1YUFA 1EMNA 3KQBL 1G1QA 1EQHA 3CFWA 2Y5HL 4C16A 5JBBE 1V1IA 1NQLB 3C9AC 3TK6B 4OTYA 3TBDA 3U73A 1RFNB 1L3YA 4X8UL 4Y79B 3ZYGA 4O02B 1IVOC 1X7AL 3TK5B 5CISA 4YZUB 2FD6A 2P26A 2BQWA 1ATEA 2XBWL 1FE2A 3FFGL 1WU1B 4NGAL 3ZYIB 1XKAL 4Y6DB 2KB9A 2BZ6L 1EAIC 2WPIE
chains in the Genus database with same CATH topology
1LMMA 4M11A 1DX5I 5JVYA 1IQNL 3HO4A 1DDXA 5JW1A 1LPKA 3HS7A 3KQEL 2W2OE 4MMYB 2Y80B 3GCWE 3LIWB 1N7DA 2FLGA 2P3TA 1KSNB 1HZ8A 2P94L 3LTFB 2BQ7A 4COXA 4X8VL 5JVZA 4ZH8B 2RHPA 1KIGL 1G1TA 3LTGD 5JB9E 4YT6L 1XKBA 4X8TL 1EMOA 5L2YL 2YGQA 2PHBB 2K2TA 4AQTA 3PGHA 5EGMB 6COXA 4LMFA 2VJ3A 2WFTA 5IKRA 1LMJA 1FAKL 1HJ7A 4ZAEB 4X8SL 2XC4L 3KK6A 2J34B 1PFXL 2Y7ZB 4MMZB 3KQCL 1WHFA 1G1SA 1O5DL 1Z6EL 2WPJE 4Y71B 2Y38A 1J9CL 1ADXA 2BOKL 1DQBA 2P16L 1NPEB 2WPLE 2YGPA 3HS5A 1FF7A 2J94B 4BDWA 2Y7XB 4MMXB 2VH0B 1MOXC 5FDQA 2J4IB 1HT5A 3KQDL 2K2SB 3GCXE 5L2ZL 1Z6CA 2KL7A 4YT7L 4BTIA 3HO5A 3POYA 2MHPA 2BOHA 2W3KB 1UZQA 1F0RB 3GISX 3V64C 4TGFA 3N8YB 1HREA 2WG4B 5IKQA 2YGOA 2RA0L 1EGFA 2W2NE 4O1ZA 4ISIL 1CVUA 4XLWA 4A7IA 3ELAL 3EGFA 5IKTA 3IITB 1IQKL 2WG3C 4NG9L 1PGEA 3S6XA 2BQ6A 3N8WA 1URKA 3SW2A 1K36A 1CVWL 5CKQA 4JZFL 2MGRA 2Y5FL 1ATAA 1ZAQA 1JL9A 2GD4A 4Z0LA 3LAQA 2XC0L 3CENL 1U67A 3TGFA 5IKVA 3CS7L 5F19A 1PXXA 1MQ5L 4Y7AB 3SOVA 2RNLA 1HCGB 5CKNA 1LPZA 3BT2A 1G2MB 3NJPC 1Q4GA 1IOXA 1TOZA 2WPME 3KL6B 1L5GB 1G2LB 3LN0A 4CUFA 3ASIA 3KCGL 1EPIA 1V3XB 2XBVL 2W3IB 2W26B 4LORA 1F0SB 1F7EA 1YGCL 3HO3A 3M36L 1IQJL 1NFWB 1TLEA 1B9WA 1EPGA 4NA9L 1YUGA 2EI8B 2VWLL 4JYUL 3N8WB 2D1JB 3N8YA 2KV4A 1GK5A 4JZDL 3H5CB 1EPHA 2NPRA 2WPHE 1AUTL 2FLBL 3NTBA 3QH0A 3Q3KB 1HT8A 4A94C 5JB8E 3OLTA 3BPSE 1HAEA 3HS6A 1IGZA 1PTHA 1FSBA 4RRXA 5E8DA 1IQFL 3FCSB 5JBCE 3DEMA 2BOXA 1KLIL 1BF9A 2XBXL 1OB1C 4PH9A 5KIRA 2OYEP 1XFEA 1TPGA 1P9JA 3P5BL 1APOA 1M1XB 1ATBA 1MQ6L 1A3PA 1ATDA 1KLJL 2W2ME 2M74A 4ZXYL 4RRYA 4CUEA 4OTJA 3R05A 1K37A 2P95L 2VVUL 2Q1JB 4D90A 5COXA 3LN1A 1I0UA 1CQEA 2WZPP 1YUKB 3QMOA 4RRWA 4BTUA 2JKHL 3SOBB 1NFUB 5I46L 2VWNL 3N8ZA 3MQEA 1IQGL 2UWOB 5CKMA 3LC5B 3HPTA 4ZXXL 2AYLA 4Y76B 3SOQA 4JYVL 1NT0A 2W86A 1NFYB 2Y5GL 2Y81B 2J38B 2H9EL 1LQDA 1C5MF 3F1SB 1HAFA 1W8BL 2I9BA 4Z0KB 1NZIA 2J2UB 3M37L 3QCWA 1HX2A 1UZKA 3CA7A 4RS0A 2EI6B 2XC5L 5F1AA 4BXWA 3KRKA 4M10A 3IJEB 4E1GA 1CCVA 2UWLB 2B7DL 1IQLL 2Y82B 2CJIB 2ADXA 2FLRL 2WYGB 1IQIL 1CEJA 1YO8A 1F7MA 4JZEL 2BO2A 2J95B 2MGPA 1IJQA 3ZYJB 4FM5A 3RR3A 2OYUP 2VWOL 3NTGA 1EQGA 3V65B 1DIYA 3ENSA 5KN5C 1EPJA 4XBMA 4BTTA 1KLOA 4G1MB 1P0SL 4Z6AL 2VWMK 4D0FA 4RUTA 1JV2B 2VH6B 2VVCK 2P3FN 3F6UL 1WHEA 2W2PE 1DVAL 1UZPA 2WFXB 1SZBA 3TZIA 1IGXA 1CCFA 4ZHAB 1IQHL 1EZQB 3LC3B 3N8XA 2P28B 2XBYL 1PRHA 3MDLA 2PUQL 2FZZL 2WPKE 2KNIA 3U7UG 2W2QE 1NFXB 1QFKL 3Q7DA 2WYJB 4ISHL 1IQML 1JBUL 4BXSA 1CX2A 2F9BL 2VVVL 2TGFA 2P93L 3NT1A 1APQA 3FBYA 2P3UA 1U8CB 1XDTR 4D0EA 4BDXA 2BOUA 5JBAE 3TH3L 2EI7B 3BT1A 1EBVA 3K9XA 2UWPB 5K0HB 1FAXL 1W7XL 1FFMA 4Y7BB 2BMGA 1N1IA 2I9AA 1IOEL 3OLUA 1IP0A 2H9EC 4RRZA 1LPGA 2P3FL 2DDUA 4CUDA 1UZJA 1G1RA 1COUA 4XL1A 2G00L 1HRFA 4CSYA 5L30L 3N8VA 1FJSL 2PR3B 1IQEL 1YUFA 1EMNA 3KQBL 1G1QA 1EQHA 3CFWA 2Y5HL 4C16A 5JBBE 1NQLB 3C9AC 3TK6B 4OTYA 3TBDA 3U73A 1RFNB 1L3YA 4X8UL 4Y79B 3ZYGA 4O02B 1IVOC 1X7AL 3TK5B 5CISA 4YZUB 2FD6A 2P26A 2BQWA 1ATEA 2XBWL 1FE2A 3FFGL 1WU1B 4NGAL 3ZYIB 1XKAL 4Y6DB 2KB9A 2BZ6L 1EAIC 2WPIE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4M11 A;  1DX5 I;  5JVY A;  1IQN L;  3HO4 A;  1DDX A;  5JW1 A;  1LPK A;  3HS7 A;  3KQE L;  2W2O E;  4MMY B;  2Y80 B;  3GCW E;  3LIW B;  1N7D A;  2FLG A;  2P3T A;  1KSN B;  1HZ8 A;  2P94 L;  3LTF B;  2BQ7 A;  4COX A;  4X8V L;  5JVZ A;  4ZH8 B;  2RHP A;  1KIG L;  1G1T A;  3LTG D;  5JB9 E;  4YT6 L;  1XKB A;  4X8T L;  1EMO A;  5L2Y L;  2PHB B;  2K2T A;  4AQT A;  3PGH A;  5EGM B;  6COX A;  4LMF A;  2VJ3 A;  2WFT A;  5IKR A;  1LMJ A;  1FAK L;  1HJ7 A;  4ZAE B;  4X8S L;  2XC4 L;  3KK6 A;  2J34 B;  1PFX L;  2Y7Z B;  4MMZ B;  3KQC L;  1WHF A;  1G1S A;  1O5D L;  1Z6E L;  2WPJ E;  4Y71 B;  2Y38 A;  1J9C L;  1ADX A;  2BOK L;  1DQB A;  2P16 L;  1NPE B;  2WPL E;  2YGP A;  3HS5 A;  1FF7 A;  2J94 B;  4BDW A;  2Y7X B;  4MMX B;  2VH0 B;  1MOX C;  5FDQ A;  2J4I B;  1HT5 A;  3KQD L;  2K2S B;  3GCX E;  5L2Z L;  1Z6C A;  2KL7 A;  4YT7 L;  4BTI A;  3HO5 A;  3POY A;  2MHP A;  2BOH A;  2W3K B;  1UZQ A;  1F0R B;  3GIS X;  3V64 C;  4TGF A;  3N8Y B;  1HRE A;  2WG4 B;  5IKQ A;  2YGO A;  2RA0 L;  1EGF A;  2W2N E;  4O1Z A;  4ISI L;  1CVU A;  4XLW A;  4A7I A;  3ELA L;  3EGF A;  5IKT A;  3IIT B;  1IQK L;  2WG3 C;  4NG9 L;  1PGE A;  2BQ6 A;  3N8W A;  1URK A;  3SW2 A;  1K36 A;  1CVW L;  5CKQ A;  4JZF L;  2MGR A;  2Y5F L;  1ATA A;  1ZAQ A;  1JL9 A;  2GD4 A;  4Z0L A;  3LAQ A;  2XC0 L;  3CEN L;  1U67 A;  3TGF A;  5IKV A;  3CS7 L;  5F19 A;  1PXX A;  1MQ5 L;  4Y7A B;  3SOV A;  2RNL A;  1HCG B;  5CKN A;  1LPZ A;  3BT2 A;  1G2M B;  3NJP C;  1Q4G A;  1IOX A;  1TOZ A;  2WPM E;  3KL6 B;  1L5G B;  1G2L B;  3LN0 A;  4CUF A;  3ASI A;  3KCG L;  1EPI A;  1V3X B;  2XBV L;  2W3I B;  2W26 B;  4LOR A;  1F0S B;  1F7E A;  1YGC L;  3HO3 A;  3M36 L;  1IQJ L;  1NFW B;  1TLE A;  1B9W A;  1EPG A;  4NA9 L;  1YUG A;  2EI8 B;  2VWL L;  4JYU L;  3N8W B;  2D1J B;  3N8Y A;  2KV4 A;  1GK5 A;  4JZD L;  3H5C B;  1EPH A;  2NPR A;  2WPH E;  1AUT L;  2FLB L;  3NTB A;  3QH0 A;  3Q3K B;  1HT8 A;  5JB8 E;  3OLT A;  3BPS E;  1HAE A;  3HS6 A;  1IGZ A;  1PTH A;  1FSB A;  4RRX A;  5E8D A;  1IQF L;  3FCS B;  5JBC E;  3DEM A;  2BOX A;  1KLI L;  1BF9 A;  2XBX L;  1OB1 C;  4PH9 A;  5KIR A;  2OYE P;  1XFE A;  1TPG A;  1P9J A;  3P5B L;  1APO A;  1M1X B;  1ATB A;  1MQ6 L;  1A3P A;  1ATD A;  1KLJ L;  2W2M E;  2M74 A;  4ZXY L;  4RRY A;  4CUE A;  4OTJ A;  3R05 A;  1K37 A;  2P95 L;  2VVU L;  2Q1J B;  4D90 A;  5COX A;  3LN1 A;  1I0U A;  1CQE A;  1YUK B;  3QMO A;  4RRW A;  4BTU A;  2JKH L;  3SOB B;  1NFU B;  5I46 L;  2VWN L;  3N8Z A;  3MQE A;  1IQG L;  2UWO B;  5CKM A;  3LC5 B;  3HPT A;  4ZXX L;  2AYL A;  4Y76 B;  3SOQ A;  4JYV L;  1NT0 A;  2W86 A;  1NFY B;  2Y5G L;  2Y81 B;  2J38 B;  2H9E L;  1LQD A;  1C5M F;  3F1S B;  1HAF A;  1W8B L;  2I9B A;  4Z0K B;  1NZI A;  2J2U B;  3M37 L;  3QCW A;  1HX2 A;  1UZK A;  3CA7 A;  4RS0 A;  2EI6 B;  2XC5 L;  5F1A A;  4BXW A;  3KRK A;  4M10 A;  3IJE B;  4E1G A;  1CCV A;  2UWL B;  2B7D L;  1IQL L;  2Y82 B;  2CJI B;  2ADX A;  2FLR L;  2WYG B;  1IQI L;  1CEJ A;  1YO8 A;  1F7M A;  4JZE L;  2BO2 A;  2J95 B;  2MGP A;  1IJQ A;  3ZYJ B;  4FM5 A;  3RR3 A;  2OYU P;  2VWO L;  3NTG A;  1EQG A;  3V65 B;  1DIY A;  3ENS A;  5KN5 C;  1EPJ A;  4XBM A;  4BTT A;  1KLO A;  4G1M B;  1P0S L;  4Z6A L;  2VWM K;  4D0F A;  4RUT A;  1JV2 B;  2VH6 B;  2VVC K;  2P3F N;  3F6U L;  1WHE A;  2W2P E;  1DVA L;  1UZP A;  2WFX B;  1SZB A;  3TZI A;  1IGX A;  1CCF A;  4ZHA B;  1IQH L;  1EZQ B;  3LC3 B;  3N8X A;  2P28 B;  2XBY L;  1PRH A;  3MDL A;  2PUQ L;  2FZZ L;  2WPK E;  3U7U G;  2W2Q E;  1NFX B;  1QFK L;  3Q7D A;  2WYJ B;  4ISH L;  1IQM L;  1JBU L;  4BXS A;  1CX2 A;  2F9B L;  2VVV L;  2TGF A;  2P93 L;  3NT1 A;  1APQ A;  3FBY A;  2P3U A;  1U8C B;  1XDT R;  4D0E A;  4BDX A;  2BOU A;  5JBA E;  3TH3 L;  2EI7 B;  3BT1 A;  1EBV A;  3K9X A;  2UWP B;  5K0H B;  1FAX L;  1W7X L;  1FFM A;  4Y7B B;  2BMG A;  1N1I A;  2I9A A;  1IOE L;  3OLU A;  1IP0 A;  4RRZ A;  1LPG A;  2P3F L;  2DDU A;  4CUD A;  1UZJ A;  1G1R A;  1COU A;  4XL1 A;  2G00 L;  1HRF A;  4CSY A;  5L30 L;  3N8V A;  1FJS L;  2PR3 B;  1IQE L;  1YUF A;  1EMN A;  3KQB L;  1G1Q A;  1EQH A;  3CFW A;  2Y5H L;  4C16 A;  5JBB E;  1NQL B;  3C9A C;  3TK6 B;  4OTY A;  3TBD A;  3U73 A;  1RFN B;  1L3Y A;  4X8U L;  4Y79 B;  3ZYG A;  4O02 B;  1IVO C;  1X7A L;  3TK5 B;  5CIS A;  4YZU B;  2FD6 A;  2P26 A;  2BQW A;  1ATE A;  2XBW L;  1FE2 A;  3FFG L;  1WU1 B;  4NGA L;  3ZYI B;  1XKA L;  4Y6D B;  2KB9 A;  2BZ6 L;  1EAI C;  2WPI E; 
#chains in the Genus database with same CATH topology
 1LMM A;  4M11 A;  1DX5 I;  5JVY A;  1IQN L;  3HO4 A;  1DDX A;  5JW1 A;  1LPK A;  3HS7 A;  3KQE L;  2W2O E;  4MMY B;  4GU4 A;  2Y80 B;  3GCW E;  3LIW B;  1N7D A;  2FLG A;  2P3T A;  1KSN B;  1HZ8 A;  2P94 L;  3LTF B;  2BQ7 A;  4COX A;  4X8V L;  5JVZ A;  4ZH8 B;  2RHP A;  1KIG L;  1G1T A;  3LTG D;  5JB9 E;  4YT6 L;  1XKB A;  4X8T L;  1EMO A;  5L2Y L;  2YGQ A;  2PHB B;  2K2T A;  4AQT A;  3PGH A;  5EGM B;  6COX A;  4LMF A;  2VJ3 A;  2WFT A;  5IKR A;  1LMJ A;  1FAK L;  1HJ7 A;  4ZAE B;  4X8S L;  2XC4 L;  3KK6 A;  2J34 B;  1PFX L;  2Y7Z B;  4MMZ B;  3KQC L;  1WHF A;  1G1S A;  1O5D L;  1Z6E L;  2WPJ E;  4Y71 B;  2Y38 A;  1J9C L;  1ADX A;  2BOK L;  1DQB A;  2P16 L;  1NPE B;  2WPL E;  2YGP A;  3HS5 A;  1FF7 A;  2J94 B;  4BDW A;  2Y7X B;  4MMX B;  2VH0 B;  1MOX C;  5FDQ A;  2J4I B;  1HT5 A;  3KQD L;  2K2S B;  3GCX E;  5L2Z L;  1Z6C A;  2KL7 A;  4YT7 L;  4BTI A;  3HO5 A;  3POY A;  2MHP A;  2BOH A;  2W3K B;  1UZQ A;  1F0R B;  3GIS X;  3V64 C;  4TGF A;  3N8Y B;  1HRE A;  2WG4 B;  5IKQ A;  1LK9 A;  2YGO A;  2RA0 L;  1EGF A;  2W2N E;  4O1Z A;  4ISI L;  1CVU A;  4XLW A;  4A7I A;  3ELA L;  3EGF A;  1V1H A;  5IKT A;  3IIT B;  1IQK L;  2WG3 C;  4NG9 L;  1PGE A;  3S6X A;  2BQ6 A;  3N8W A;  1URK A;  3SW2 A;  1K36 A;  1CVW L;  5CKQ A;  4JZF L;  2MGR A;  2Y5F L;  1ATA A;  1ZAQ A;  1JL9 A;  2GD4 A;  4Z0L A;  3LAQ A;  2XC0 L;  3CEN L;  1U67 A;  1KKE A;  3TGF A;  5IKV A;  3CS7 L;  5F19 A;  2HOX A;  1PXX A;  1MQ5 L;  4Y7A B;  3SOV A;  2RNL A;  1HCG B;  5CKN A;  1LPZ A;  3BT2 A;  1G2M B;  3NJP C;  1Q4G A;  1IOX A;  1TOZ A;  2WPM E;  3KL6 B;  2BSF A;  1L5G B;  1G2L B;  3LN0 A;  4CUF A;  3ASI A;  3KCG L;  1EPI A;  1V3X B;  2XBV L;  2W3I B;  2W26 B;  4LOR A;  1F0S B;  1F7E A;  1YGC L;  3HO3 A;  3M36 L;  1IQJ L;  1NFW B;  1TLE A;  1B9W A;  1EPG A;  4NA9 L;  1YUG A;  2EI8 B;  2VWL L;  4JYU L;  3N8W B;  2D1J B;  3N8Y A;  2KV4 A;  1GK5 A;  4JZD L;  3H5C B;  1EPH A;  2NPR A;  2WPH E;  1AUT L;  2FLB L;  3NTB A;  3QH0 A;  3Q3K B;  1HT8 A;  4A94 C;  5JB8 E;  3OLT A;  3BPS E;  1HAE A;  3HS6 A;  1IGZ A;  1PTH A;  1FSB A;  4RRX A;  5E8D A;  1IQF L;  3FCS B;  5JBC E;  3DEM A;  2BOX A;  1KLI L;  1BF9 A;  2XBX L;  1OB1 C;  4PH9 A;  5KIR A;  2OYE P;  1XFE A;  1TPG A;  1P9J A;  3P5B L;  1APO A;  1M1X B;  1ATB A;  1MQ6 L;  1A3P A;  1ATD A;  1KLJ L;  2W2M E;  2M74 A;  4ZXY L;  4RRY A;  4CUE A;  4OTJ A;  3R05 A;  1K37 A;  2BT7 A;  2P95 L;  2VVU L;  2Q1J B;  4D90 A;  5COX A;  3LN1 A;  1I0U A;  1CQE A;  2WZP P;  1YUK B;  3QMO A;  4RRW A;  1QIU A;  4BTU A;  2JKH L;  3SOB B;  1NFU B;  5I46 L;  2VWN L;  3N8Z A;  3MQE A;  1IQG L;  2UWO B;  5CKM A;  3LC5 B;  3HPT A;  4ZXX L;  2AYL A;  4Y76 B;  3SOQ A;  4JYV L;  1NT0 A;  2W86 A;  1NFY B;  2Y5G L;  2Y81 B;  2J38 B;  2H9E L;  1LQD A;  1C5M F;  3F1S B;  1HAF A;  1W8B L;  2HOR A;  2I9B A;  4Z0K B;  1NZI A;  2J2U B;  3M37 L;  3QCW A;  1HX2 A;  1UZK A;  3CA7 A;  4RS0 A;  2EI6 B;  2XC5 L;  5F1A A;  4BXW A;  3KRK A;  4M10 A;  3IJE B;  4E1G A;  1CCV A;  2UWL B;  2B7D L;  1IQL L;  2Y82 B;  2CJI B;  2VRS A;  2ADX A;  2FLR L;  2WYG B;  1IQI L;  1CEJ A;  1YO8 A;  1F7M A;  2BT8 A;  2BO2 A;  4JZE L;  2J95 B;  2MGP A;  1IJQ A;  3ZYJ B;  4FM5 A;  3RR3 A;  2OYU P;  2VWO L;  3NTG A;  1EQG A;  3V65 B;  1DIY A;  3ENS A;  5KN5 C;  1EPJ A;  4XBM A;  4BTT A;  1KLO A;  4G1M B;  1P0S L;  4Z6A L;  2VWM K;  4D0F A;  4RUT A;  1JV2 B;  2VH6 B;  2VVC K;  2P3F N;  3F6U L;  1WHE A;  2W2P E;  1DVA L;  1UZP A;  2WFX B;  1SZB A;  3TZI A;  1IGX A;  1CCF A;  4ZHA B;  1IQH L;  1EZQ B;  3LC3 B;  3N8X A;  2P28 B;  2XBY L;  1PRH A;  3MDL A;  2PUQ L;  2FZZ L;  2WPK E;  2KNI A;  3U7U G;  2W2Q E;  1NFX B;  1QFK L;  2JJL A;  3Q7D A;  2WYJ B;  4ISH L;  1IQM L;  1JBU L;  4BXS A;  1CX2 A;  2F9B L;  2VVV L;  2TGF A;  2P93 L;  3NT1 A;  1APQ A;  3FBY A;  2P3U A;  1U8C B;  1XDT R;  4D0E A;  4BDX A;  2BOU A;  5JBA E;  3TH3 L;  2EI7 B;  3BT1 A;  1EBV A;  3K9X A;  2UWP B;  5K0H B;  1FAX L;  1W7X L;  1FFM A;  4Y7B B;  2BMG A;  1N1I A;  2I9A A;  1IOE L;  3OLU A;  1IP0 A;  2H9E C;  4RRZ A;  1LPG A;  2P3F L;  2DDU A;  4CUD A;  1UZJ A;  1G1R A;  1COU A;  4XL1 A;  2G00 L;  1HRF A;  4CSY A;  5L30 L;  3N8V A;  1FJS L;  2PR3 B;  4GU3 A;  1IQE L;  1YUF A;  1EMN A;  3KQB L;  1G1Q A;  1EQH A;  3CFW A;  2Y5H L;  4C16 A;  5JBB E;  1V1I A;  1NQL B;  3C9A C;  3TK6 B;  4OTY A;  3TBD A;  3U73 A;  1RFN B;  1L3Y A;  4X8U L;  4Y79 B;  3ZYG A;  4O02 B;  1IVO C;  1X7A L;  3TK5 B;  5CIS A;  4YZU B;  2FD6 A;  2P26 A;  2BQW A;  1ATE A;  2XBW L;  1FE2 A;  3FFG L;  1WU1 B;  4NGA L;  3ZYI B;  1XKA L;  4Y6D B;  2KB9 A;  2BZ6 L;  1EAI C;  2WPI E; 
#chains in the Genus database with same CATH homology
 1LMM A;  4M11 A;  1DX5 I;  5JVY A;  1IQN L;  3HO4 A;  1DDX A;  5JW1 A;  1LPK A;  3HS7 A;  3KQE L;  2W2O E;  4MMY B;  2Y80 B;  3GCW E;  3LIW B;  1N7D A;  2FLG A;  2P3T A;  1KSN B;  1HZ8 A;  2P94 L;  3LTF B;  2BQ7 A;  4COX A;  4X8V L;  5JVZ A;  4ZH8 B;  2RHP A;  1KIG L;  1G1T A;  3LTG D;  5JB9 E;  4YT6 L;  1XKB A;  4X8T L;  1EMO A;  5L2Y L;  2YGQ A;  2PHB B;  2K2T A;  4AQT A;  3PGH A;  5EGM B;  6COX A;  4LMF A;  2VJ3 A;  2WFT A;  5IKR A;  1LMJ A;  1FAK L;  1HJ7 A;  4ZAE B;  4X8S L;  2XC4 L;  3KK6 A;  2J34 B;  1PFX L;  2Y7Z B;  4MMZ B;  3KQC L;  1WHF A;  1G1S A;  1O5D L;  1Z6E L;  2WPJ E;  4Y71 B;  2Y38 A;  1J9C L;  1ADX A;  2BOK L;  1DQB A;  2P16 L;  1NPE B;  2WPL E;  2YGP A;  3HS5 A;  1FF7 A;  2J94 B;  4BDW A;  2Y7X B;  4MMX B;  2VH0 B;  1MOX C;  5FDQ A;  2J4I B;  1HT5 A;  3KQD L;  2K2S B;  3GCX E;  5L2Z L;  1Z6C A;  2KL7 A;  4YT7 L;  4BTI A;  3HO5 A;  3POY A;  2MHP A;  2BOH A;  2W3K B;  1UZQ A;  1F0R B;  3GIS X;  3V64 C;  4TGF A;  3N8Y B;  1HRE A;  2WG4 B;  5IKQ A;  2YGO A;  2RA0 L;  1EGF A;  2W2N E;  4O1Z A;  4ISI L;  1CVU A;  4XLW A;  4A7I A;  3ELA L;  3EGF A;  5IKT A;  3IIT B;  1IQK L;  2WG3 C;  4NG9 L;  1PGE A;  3S6X A;  2BQ6 A;  3N8W A;  1URK A;  3SW2 A;  1K36 A;  1CVW L;  5CKQ A;  4JZF L;  2MGR A;  2Y5F L;  1ATA A;  1ZAQ A;  1JL9 A;  2GD4 A;  4Z0L A;  3LAQ A;  2XC0 L;  3CEN L;  1U67 A;  3TGF A;  5IKV A;  3CS7 L;  5F19 A;  1PXX A;  1MQ5 L;  4Y7A B;  3SOV A;  2RNL A;  1HCG B;  5CKN A;  1LPZ A;  3BT2 A;  1G2M B;  3NJP C;  1Q4G A;  1IOX A;  1TOZ A;  2WPM E;  3KL6 B;  1L5G B;  1G2L B;  3LN0 A;  4CUF A;  3ASI A;  3KCG L;  1EPI A;  1V3X B;  2XBV L;  2W3I B;  2W26 B;  4LOR A;  1F0S B;  1F7E A;  1YGC L;  3HO3 A;  3M36 L;  1IQJ L;  1NFW B;  1TLE A;  1B9W A;  1EPG A;  4NA9 L;  1YUG A;  2EI8 B;  2VWL L;  4JYU L;  3N8W B;  2D1J B;  3N8Y A;  2KV4 A;  1GK5 A;  4JZD L;  3H5C B;  1EPH A;  2NPR A;  2WPH E;  1AUT L;  2FLB L;  3NTB A;  3QH0 A;  3Q3K B;  1HT8 A;  4A94 C;  5JB8 E;  3OLT A;  3BPS E;  1HAE A;  3HS6 A;  1IGZ A;  1PTH A;  1FSB A;  4RRX A;  5E8D A;  1IQF L;  3FCS B;  5JBC E;  3DEM A;  2BOX A;  1KLI L;  1BF9 A;  2XBX L;  1OB1 C;  4PH9 A;  5KIR A;  2OYE P;  1XFE A;  1TPG A;  1P9J A;  3P5B L;  1APO A;  1M1X B;  1ATB A;  1MQ6 L;  1A3P A;  1ATD A;  1KLJ L;  2W2M E;  2M74 A;  4ZXY L;  4RRY A;  4CUE A;  4OTJ A;  3R05 A;  1K37 A;  2P95 L;  2VVU L;  2Q1J B;  4D90 A;  5COX A;  3LN1 A;  1I0U A;  1CQE A;  2WZP P;  1YUK B;  3QMO A;  4RRW A;  4BTU A;  2JKH L;  3SOB B;  1NFU B;  5I46 L;  2VWN L;  3N8Z A;  3MQE A;  1IQG L;  2UWO B;  5CKM A;  3LC5 B;  3HPT A;  4ZXX L;  2AYL A;  4Y76 B;  3SOQ A;  4JYV L;  1NT0 A;  2W86 A;  1NFY B;  2Y5G L;  2Y81 B;  2J38 B;  2H9E L;  1LQD A;  1C5M F;  3F1S B;  1HAF A;  1W8B L;  2I9B A;  4Z0K B;  1NZI A;  2J2U B;  3M37 L;  3QCW A;  1HX2 A;  1UZK A;  3CA7 A;  4RS0 A;  2EI6 B;  2XC5 L;  5F1A A;  4BXW A;  3KRK A;  4M10 A;  3IJE B;  4E1G A;  1CCV A;  2UWL B;  2B7D L;  1IQL L;  2Y82 B;  2CJI B;  2ADX A;  2FLR L;  2WYG B;  1IQI L;  1CEJ A;  1YO8 A;  1F7M A;  4JZE L;  2BO2 A;  2J95 B;  2MGP A;  1IJQ A;  3ZYJ B;  4FM5 A;  3RR3 A;  2OYU P;  2VWO L;  3NTG A;  1EQG A;  3V65 B;  1DIY A;  3ENS A;  5KN5 C;  1EPJ A;  4XBM A;  4BTT A;  1KLO A;  4G1M B;  1P0S L;  4Z6A L;  2VWM K;  4D0F A;  4RUT A;  1JV2 B;  2VH6 B;  2VVC K;  2P3F N;  3F6U L;  1WHE A;  2W2P E;  1DVA L;  1UZP A;  2WFX B;  1SZB A;  3TZI A;  1IGX A;  1CCF A;  4ZHA B;  1IQH L;  1EZQ B;  3LC3 B;  3N8X A;  2P28 B;  2XBY L;  1PRH A;  3MDL A;  2PUQ L;  2FZZ L;  2WPK E;  2KNI A;  3U7U G;  2W2Q E;  1NFX B;  1QFK L;  3Q7D A;  2WYJ B;  4ISH L;  1IQM L;  1JBU L;  4BXS A;  1CX2 A;  2F9B L;  2VVV L;  2TGF A;  2P93 L;  3NT1 A;  1APQ A;  3FBY A;  2P3U A;  1U8C B;  1XDT R;  4D0E A;  4BDX A;  2BOU A;  5JBA E;  3TH3 L;  2EI7 B;  3BT1 A;  1EBV A;  3K9X A;  2UWP B;  5K0H B;  1FAX L;  1W7X L;  1FFM A;  4Y7B B;  2BMG A;  1N1I A;  2I9A A;  1IOE L;  3OLU A;  1IP0 A;  2H9E C;  4RRZ A;  1LPG A;  2P3F L;  2DDU A;  4CUD A;  1UZJ A;  1G1R A;  1COU A;  4XL1 A;  2G00 L;  1HRF A;  4CSY A;  5L30 L;  3N8V A;  1FJS L;  2PR3 B;  1IQE L;  1YUF A;  1EMN A;  3KQB L;  1G1Q A;  1EQH A;  3CFW A;  2Y5H L;  4C16 A;  5JBB E;  1NQL B;  3C9A C;  3TK6 B;  4OTY A;  3TBD A;  3U73 A;  1RFN B;  1L3Y A;  4X8U L;  4Y79 B;  3ZYG A;  4O02 B;  1IVO C;  1X7A L;  3TK5 B;  5CIS A;  4YZU B;  2FD6 A;  2P26 A;  2BQW A;  1ATE A;  2XBW L;  1FE2 A;  3FFG L;  1WU1 B;  4NGA L;  3ZYI B;  1XKA L;  4Y6D B;  2KB9 A;  2BZ6 L;  1EAI C;  2WPI E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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