2FZZL

Factor xa in complex with the inhibitor 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(2'-(((3r)-3-hydroxy-1-pyrrolidinyl)methyl)-4-biphenylyl)-3-(trifluoromethyl)-1,4,5,6-tetrahydro-7h-pyrazolo[3,4-c]pyridin-7-one
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title 1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Coagulation factor X
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2006-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2fzzL00
1W7XL 1K37A 3CA7A 1EPGA 5IKQA 4CUEA 4OTYA 5CKMA 3F1SB 2VWMK 2RA0L 2VJ3A 3ZYJB 3RR3A 2YGPA 2W26B 1TLEA 2WFTA 4XL1A 3MDLA 2Y7ZB 3DEMA 2TGFA 4XBMA 1XKBA 1U67A 1CQEA 1CX2A 1FAKL 1YO8A 1UZKA 1CVUA 4X8UL 2YGOA 3M37L 2W2OE 1NZIA 2XC4L 2VWLL 1DDXA 1KIGL 1IGXA 1IQML 4G1MB 1IP0A 2WPME 3QH0A 3BT2A 2BOXA 3KQEL 2UWLB 3SOQA 1N7DA 1Z6CA 1XDTR 2W2ME 4ISHL 1CEJA 1P9JA 1XKAL 2VH6B 3K9XA 3KL6B 1KLOA 1IQJL 2J38B 1G2LB 2P3FL 4Z6AL 3EGFA 1G1SA 5COXA 1HT8A 2B7DL 1URKA 2UWPB 2VWOL 2BOUA 1DQBA 4O1ZA 2J95B 1BF9A 3CS7L 1F7EA 5L2YL 1DVAL 2Q1JB 3ENSA 4YZUB 1UZPA 1V3XB 3TGFA 1G1TA 4NA9L 1FF7A 3SW2A 3HPTA 4Y7AB 1ATAA 1SZBA 2Y38A 1WU1B 4YT6L 2PHBB 2P26A 2F9BL 1Z6EL 4A7IA 2VVVL 3MQEA 1HJ7A 3F6UL 1YUKB 1PRHA 1PGEA 2P93L 1NFWB 4C16A 2K2SB 1B9WA 2MGRA 4E1GA 2Y80B 1EMOA 3M36L 2OYEP 3N8YB 1HAEA 1LQDA 3Q3KB 1OB1C 2GD4A 1IOEL 5KIRA 3KRKA 2Y5FL 3TBDA 1G1QA 1HX2A 1IGZA 4D90A 1MQ6L 1F0SB 3GCXE 3LC5B 3HO4A 1IQIL 1YGCL 4Y79B 1CCFA 3OLUA 4ISIL 1TOZA 4OTJA 1HCGB 2XC5L 2J2UB 1C5MF 5CISA 4RRXA 2FLRL 1EGFA 4MMZB 2XC0L 5I46L 1CVWL 1J9CL 2VVUL 1YUFA 2I9AA 1IQEL 4M11A 1NT0A 1NFYB 1LMJA 4Z0KB 5JBCE 2NPRA 3QMOA 5IKTA 1WHEA 3NTGA 2W86A 3N8WA 4D0EA 5F19A 2KV4A 2KL7A 5IKVA 5JW1A 3C9AC 1IVOC 2WPIE 1HRFA 4ZH8B 4FM5A 3U7UG 2G00L 2XBWL 3KQDL 1LPGA 5L2ZL 2RHPA 4BXWA 4JYUL 2BQWA 2EI6B 1G2MB 3TH3L 1Q4GA 2WPLE 5EGMB 2WPJE 4X8TL 5K0HB 3IITB 1N1IA 1DX5I 1NPEB 1PFXL 1FSBA 4NGAL 1MOXC 1EBVA 3QCWA 1EAIC 3P5BL 3V64C 1IJQA 1EMNA 6COXA 2WYGB 3LN1A 1TPGA 3HS6A 5JB9E 2XBXL 1ZAQA 1EQHA 3Q7DA 4Y76B 3R05A 1O5DL 1KSNB 3N8YA 1W8BL 1QFKL 5CKQA 2P28B 2FZZL 4NG9L 4ZXXL 3HO5A 2VWNL 3KCGL 2WYJB 2BO2A 4JYVL 1NFUB 1NQLB 2JKHL 1IQKL 1I0UA 2CJIB 2P3TA 4JZDL 4X8SL 1ATBA 4D0FA 4JZEL 2KB9A 2P3FN 2P95L 4Y7BB 3N8VA 1FAXL 2BMGA 2DDUA 4Y6DB 3U73A 4ZHAB 1HZ8A 2H9EL 2BQ7A 2ADXA 1IQHL 5F1AA 3SOBB 4CUDA 3POYA 1RFNB 1UZQA 1IQLL 1U8CB 1JBUL 1ATEA 3N8ZA 4JZFL 3TK5B 5FDQA 2J4IB 3KQCL 3ZYIB 5JBBE 1P0SL 3LC3B 5JBAE 3LAQA 4BDWA 3LN0A 2XBYL 4O02B 1EPJA 3V65B 4RRYA 1WHFA 1F0RB 2BZ6L 4MMYB 5JB8E 4LORA 2M74A 1LPKA 3KQBL 1APOA 3CENL 2W3KB 2RNLA 2Y81B 3N8XA 1EPIA 5CKNA 1KLIL 3BPSE 4CUFA 3HS7A 1M1XB 1HT5A 1F7MA 3ZYGA 3SOVA 4BXSA 3OLTA 4CSYA 4MMXB 1FE2A 2BOKL 4ZAEB 2J34B 5JVZA 4TGFA 2BOHA 1GK5A 1ADXA 3NJPC 1EZQB 3NT1A 2OYUP 2FLBL 3HO3A 2P94L 5KN5C 3LTFB 3TZIA 4BTTA 1ATDA 4COXA 2EI8B 1FFMA 3FFGL 1PTHA 2EI7B 3IJEB 1FJSL 5IKRA 4X8VL 2I9BA 2MGPA 2UWOB 4M10A 3N8WB 4ZXYL 3KK6A 5L30L 1UZJA 3BT1A 1CCVA 2WG4B 1NFXB 4BTUA 4RRZA 2VVCK 2MHPA 1COUA 1AUTL 2FD6A 1JV2B 2PR3B 2WPKE 1DIYA 4Y71B 4BDXA 1EQGA 2AYLA 3FCSB 1L3YA 2XBVL 1X7AL 1IQNL 1HAFA 2D1JB 4PH9A 4Z0LA 2Y5HL 3GISX 2W2PE 1HREA 3FBYA 2WG3C 1KLJL 3ASIA 2P16L 5JVYA 3PGHA 5E8DA 2K2TA 4AQTA 2J94B 3LTGD 1EPHA 2PUQL 1G1RA 4BTIA 1K36A 2Y82B 2W2NE 3NTBA 1PXXA 3CFWA 3H5CB 3LIWB 3HS5A 1YUGA 2P3UA 3TK6B 4YT7L 2Y5GL 4RRWA 3GCWE 2Y7XB 4RS0A 2VH0B 1APQA 4RUTA 1IQFL 2BQ6A 1JL9A 1A3PA 2WPHE 4XLWA 2W2QE 1LPZA 1XFEA 4LMFA 1IOXA 1L5GB 2WFXB 2W3IB 3ELAL 2FLGA 1MQ5L 1IQGL
chains in the Genus database with same CATH superfamily
1W7XL 1K37A 3CA7A 1EPGA 5IKQA 4CUEA 4OTYA 5CKMA 3F1SB 2VWMK 2YGQA 2RA0L 2VJ3A 3ZYJB 3RR3A 2YGPA 2W26B 1TLEA 2WFTA 4XL1A 3MDLA 2BSFA 2Y7ZB 3DEMA 2TGFA 4XBMA 1XKBA 1U67A 1CQEA 1CX2A 1FAKL 1YO8A 1UZKA 1CVUA 4X8UL 2YGOA 3M37L 2W2OE 1NZIA 2XC4L 2VWLL 1DDXA 1KIGL 1IGXA 1IQML 4G1MB 1IP0A 2WPME 3QH0A 3BT2A 2BOXA 3KQEL 2UWLB 3SOQA 1N7DA 1Z6CA 1XDTR 2W2ME 4ISHL 1CEJA 1P9JA 1XKAL 2VH6B 3K9XA 3KL6B 1KLOA 1IQJL 2J38B 1G2LB 2P3FL 4Z6AL 3EGFA 1G1SA 5COXA 1HT8A 2B7DL 1URKA 2UWPB 2VWOL 2BOUA 1DQBA 4O1ZA 2J95B 1BF9A 3CS7L 1F7EA 5L2YL 1DVAL 2Q1JB 3ENSA 4YZUB 1UZPA 1V3XB 3TGFA 1G1TA 4NA9L 1FF7A 3SW2A 3HPTA 4Y7AB 1ATAA 1SZBA 2WZPP 2Y38A 1WU1B 4YT6L 2PHBB 2P26A 2F9BL 1Z6EL 4A7IA 2VVVL 3MQEA 1V1IA 1HJ7A 3F6UL 1YUKB 1PRHA 1PGEA 2P93L 1NFWB 4C16A 2K2SB 1B9WA 2MGRA 4E1GA 2Y80B 1EMOA 3M36L 2OYEP 3N8YB 1HAEA 1QIUA 1LQDA 3Q3KB 1OB1C 2GD4A 1IOEL 5KIRA 3KRKA 2Y5FL 3TBDA 1G1QA 1HX2A 2BT8A 1IGZA 4D90A 1MQ6L 1F0SB 3GCXE 3LC5B 3HO4A 1IQIL 1YGCL 4Y79B 1CCFA 3OLUA 4ISIL 1TOZA 4OTJA 1HCGB 2XC5L 2J2UB 1C5MF 5CISA 4RRXA 2FLRL 1EGFA 4MMZB 2XC0L 5I46L 1CVWL 1J9CL 2VVUL 1YUFA 2I9AA 1IQEL 4M11A 1NT0A 1NFYB 1LMJA 4Z0KB 5JBCE 1LK9A 2NPRA 3QMOA 5IKTA 1WHEA 3NTGA 2W86A 3N8WA 4D0EA 5F19A 2KV4A 2KL7A 5IKVA 2VRSA 5JW1A 3C9AC 1IVOC 2WPIE 4A94C 1HRFA 4ZH8B 2KNIA 4FM5A 3U7UG 2G00L 2XBWL 3KQDL 1LPGA 5L2ZL 2RHPA 4BXWA 4JYUL 2BQWA 2EI6B 1G2MB 3TH3L 1V1HA 1Q4GA 2WPLE 5EGMB 2WPJE 4X8TL 5K0HB 2BT7A 3IITB 1N1IA 1DX5I 1NPEB 1PFXL 1FSBA 4NGAL 1MOXC 1EBVA 3QCWA 1EAIC 3P5BL 3V64C 1IJQA 1EMNA 6COXA 2WYGB 3LN1A 1TPGA 3HS6A 5JB9E 2XBXL 1ZAQA 1EQHA 3Q7DA 4Y76B 3R05A 1O5DL 1KSNB 3N8YA 1W8BL 1QFKL 5CKQA 2P28B 2FZZL 4NG9L 4ZXXL 3HO5A 2VWNL 3KCGL 2WYJB 2BO2A 4JYVL 1NFUB 1NQLB 2JKHL 1IQKL 1I0UA 2CJIB 2P3TA 4JZDL 4X8SL 1ATBA 4D0FA 3S6XA 4JZEL 2KB9A 2P3FN 2P95L 4Y7BB 3N8VA 1FAXL 2BMGA 2DDUA 4Y6DB 3U73A 4ZHAB 1HZ8A 2H9EL 1LMMA 2BQ7A 2ADXA 1IQHL 5F1AA 3SOBB 4CUDA 3POYA 1RFNB 1UZQA 1IQLL 1U8CB 1JBUL 1ATEA 3N8ZA 4JZFL 3TK5B 5FDQA 2J4IB 3KQCL 3ZYIB 2HOXA 5JBBE 1P0SL 3LC3B 5JBAE 3LAQA 4BDWA 3LN0A 2XBYL 4O02B 1EPJA 3V65B 4RRYA 1WHFA 1F0RB 2BZ6L 4MMYB 5JB8E 4LORA 2M74A 1LPKA 3KQBL 1APOA 3CENL 2W3KB 2RNLA 2Y81B 3N8XA 1EPIA 5CKNA 4GU3A 1KLIL 3BPSE 4CUFA 3HS7A 1M1XB 1HT5A 1F7MA 3ZYGA 2JJLA 3SOVA 4BXSA 3OLTA 4CSYA 4MMXB 1FE2A 2BOKL 4ZAEB 2J34B 5JVZA 4TGFA 2BOHA 2HORA 1GK5A 1ADXA 3NJPC 1EZQB 3NT1A 2OYUP 2FLBL 3HO3A 2P94L 5KN5C 3LTFB 3TZIA 4BTTA 1ATDA 4COXA 2EI8B 1FFMA 3FFGL 1PTHA 2EI7B 3IJEB 1FJSL 5IKRA 4X8VL 2I9BA 2MGPA 2UWOB 4M10A 3N8WB 4ZXYL 3KK6A 5L30L 1UZJA 3BT1A 1CCVA 2WG4B 1NFXB 4BTUA 4RRZA 2VVCK 2MHPA 1COUA 1AUTL 2FD6A 1JV2B 2PR3B 2WPKE 1DIYA 4Y71B 4GU4A 1EQGA 2AYLA 4BDXA 3FCSB 1L3YA 2XBVL 1X7AL 1IQNL 1HAFA 2D1JB 4PH9A 4Z0LA 2Y5HL 3GISX 2W2PE 1HREA 3FBYA 2WG3C 1KLJL 3ASIA 2P16L 5JVYA 3PGHA 5E8DA 2K2TA 4AQTA 2J94B 3LTGD 1EPHA 2PUQL 1G1RA 4BTIA 1K36A 2Y82B 2W2NE 3NTBA 1PXXA 3CFWA 3H5CB 2H9EC 3LIWB 3HS5A 1YUGA 2P3UA 3TK6B 4YT7L 2Y5GL 4RRWA 3GCWE 2Y7XB 4RS0A 2VH0B 1APQA 4RUTA 1IQFL 2BQ6A 1JL9A 1A3PA 2WPHE 4XLWA 2W2QE 1LPZA 1KKEA 1XFEA 4LMFA 1IOXA 1L5GB 2WFXB 2W3IB 3ELAL 2FLGA 1MQ5L 1IQGL
chains in the Genus database with same CATH topology
1W7XL 1K37A 3CA7A 1EPGA 5IKQA 4CUEA 4OTYA 5CKMA 3F1SB 2VWMK 2YGQA 2RA0L 2VJ3A 3ZYJB 3RR3A 2YGPA 2W26B 1TLEA 2WFTA 4XL1A 3MDLA 2Y7ZB 3DEMA 2TGFA 4XBMA 1XKBA 1U67A 1CQEA 1CX2A 1FAKL 1YO8A 1UZKA 1CVUA 4X8UL 2YGOA 3M37L 2W2OE 1NZIA 2XC4L 2VWLL 1DDXA 1KIGL 1IGXA 1IQML 4G1MB 1IP0A 2WPME 3QH0A 3BT2A 2BOXA 3KQEL 2UWLB 3SOQA 1N7DA 1Z6CA 1XDTR 2W2ME 4ISHL 1CEJA 1P9JA 1XKAL 2VH6B 3K9XA 3KL6B 1KLOA 1IQJL 2J38B 1G2LB 2P3FL 4Z6AL 3EGFA 1G1SA 5COXA 1HT8A 2B7DL 1URKA 2UWPB 2VWOL 2BOUA 1DQBA 4O1ZA 2J95B 1BF9A 3CS7L 1F7EA 5L2YL 1DVAL 2Q1JB 3ENSA 4YZUB 1UZPA 1V3XB 3TGFA 1G1TA 4NA9L 1FF7A 3SW2A 3HPTA 4Y7AB 1ATAA 1SZBA 2WZPP 2Y38A 1WU1B 4YT6L 2PHBB 2P26A 2F9BL 1Z6EL 4A7IA 2VVVL 3MQEA 1HJ7A 3F6UL 1YUKB 1PRHA 1PGEA 2P93L 1NFWB 4C16A 2K2SB 1B9WA 2MGRA 4E1GA 2Y80B 1EMOA 3M36L 2OYEP 3N8YB 1HAEA 1LQDA 3Q3KB 1OB1C 2GD4A 1IOEL 5KIRA 3KRKA 2Y5FL 3TBDA 1G1QA 1HX2A 1IGZA 4D90A 1MQ6L 1F0SB 3GCXE 3LC5B 3HO4A 1IQIL 1YGCL 4Y79B 1CCFA 3OLUA 4ISIL 1TOZA 4OTJA 1HCGB 2XC5L 2J2UB 1C5MF 5CISA 4RRXA 2FLRL 1EGFA 4MMZB 2XC0L 5I46L 1CVWL 1J9CL 2VVUL 1YUFA 2I9AA 1IQEL 4M11A 1NT0A 1NFYB 1LMJA 4Z0KB 5JBCE 2NPRA 3QMOA 5IKTA 1WHEA 3NTGA 2W86A 3N8WA 4D0EA 5F19A 2KV4A 2KL7A 5IKVA 5JW1A 3C9AC 1IVOC 2WPIE 4A94C 1HRFA 4ZH8B 2KNIA 4FM5A 3U7UG 2G00L 2XBWL 3KQDL 1LPGA 5L2ZL 2RHPA 4BXWA 4JYUL 2BQWA 2EI6B 1G2MB 3TH3L 1Q4GA 2WPLE 5EGMB 2WPJE 4X8TL 5K0HB 3IITB 1N1IA 1DX5I 1NPEB 1PFXL 1FSBA 4NGAL 1MOXC 1EBVA 3QCWA 1EAIC 3P5BL 3V64C 1IJQA 1EMNA 6COXA 2WYGB 3LN1A 1TPGA 3HS6A 5JB9E 2XBXL 1ZAQA 1EQHA 3Q7DA 4Y76B 3R05A 1O5DL 1KSNB 3N8YA 1W8BL 1QFKL 5CKQA 2P28B 2FZZL 4NG9L 4ZXXL 3HO5A 2VWNL 3KCGL 2WYJB 2BO2A 4JYVL 1NFUB 1NQLB 2JKHL 1IQKL 1I0UA 2CJIB 2P3TA 4JZDL 4X8SL 1ATBA 4D0FA 3S6XA 4JZEL 2KB9A 2P3FN 2P95L 4Y7BB 3N8VA 1FAXL 2BMGA 2DDUA 4Y6DB 3U73A 4ZHAB 1HZ8A 2H9EL 1LMMA 2BQ7A 2ADXA 1IQHL 5F1AA 3SOBB 4CUDA 3POYA 1RFNB 1UZQA 1IQLL 1U8CB 1JBUL 1ATEA 3N8ZA 4JZFL 3TK5B 5FDQA 2J4IB 3KQCL 3ZYIB 5JBBE 1P0SL 3LC3B 5JBAE 3LAQA 4BDWA 3LN0A 2XBYL 4O02B 1EPJA 3V65B 4RRYA 1WHFA 1F0RB 2BZ6L 4MMYB 5JB8E 4LORA 2M74A 1LPKA 3KQBL 1APOA 3CENL 2W3KB 2RNLA 2Y81B 3N8XA 1EPIA 5CKNA 1KLIL 3BPSE 4CUFA 3HS7A 1M1XB 1HT5A 1F7MA 3ZYGA 3SOVA 4BXSA 3OLTA 4CSYA 4MMXB 1FE2A 2BOKL 4ZAEB 2J34B 5JVZA 4TGFA 2BOHA 1GK5A 1ADXA 3NJPC 1EZQB 3NT1A 2OYUP 2FLBL 3HO3A 2P94L 5KN5C 3LTFB 3TZIA 4BTTA 1ATDA 4COXA 2EI8B 1FFMA 3FFGL 1PTHA 2EI7B 3IJEB 1FJSL 5IKRA 4X8VL 2I9BA 2MGPA 2UWOB 4M10A 3N8WB 4ZXYL 3KK6A 5L30L 1UZJA 3BT1A 1CCVA 2WG4B 1NFXB 4BTUA 4RRZA 2VVCK 2MHPA 1COUA 1AUTL 2FD6A 1JV2B 2PR3B 2WPKE 1DIYA 4Y71B 4BDXA 1EQGA 2AYLA 3FCSB 1L3YA 2XBVL 1X7AL 1IQNL 1HAFA 2D1JB 4PH9A 4Z0LA 2Y5HL 3GISX 2W2PE 1HREA 3FBYA 2WG3C 1KLJL 3ASIA 2P16L 5JVYA 3PGHA 5E8DA 2K2TA 4AQTA 2J94B 3LTGD 1EPHA 2PUQL 1G1RA 4BTIA 1K36A 2Y82B 2W2NE 3NTBA 1PXXA 3CFWA 3H5CB 2H9EC 3LIWB 3HS5A 1YUGA 2P3UA 3TK6B 4YT7L 2Y5GL 4RRWA 3GCWE 2Y7XB 4RS0A 2VH0B 1APQA 4RUTA 1IQFL 2BQ6A 1JL9A 1A3PA 2WPHE 4XLWA 2W2QE 1LPZA 1XFEA 4LMFA 1IOXA 1L5GB 2WFXB 2W3IB 3ELAL 2FLGA 1MQ5L 1IQGL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W7X L;  1K37 A;  3CA7 A;  1EPG A;  5IKQ A;  4CUE A;  4OTY A;  5CKM A;  3F1S B;  2VWM K;  2RA0 L;  2VJ3 A;  3ZYJ B;  3RR3 A;  2YGP A;  2W26 B;  1TLE A;  2WFT A;  4XL1 A;  3MDL A;  2Y7Z B;  3DEM A;  2TGF A;  4XBM A;  1XKB A;  1U67 A;  1CQE A;  1CX2 A;  1FAK L;  1YO8 A;  1UZK A;  1CVU A;  4X8U L;  2YGO A;  3M37 L;  2W2O E;  1NZI A;  2XC4 L;  2VWL L;  1DDX A;  1KIG L;  1IGX A;  1IQM L;  4G1M B;  1IP0 A;  2WPM E;  3QH0 A;  3BT2 A;  2BOX A;  3KQE L;  2UWL B;  3SOQ A;  1N7D A;  1Z6C A;  1XDT R;  2W2M E;  4ISH L;  1CEJ A;  1P9J A;  1XKA L;  2VH6 B;  3K9X A;  3KL6 B;  1KLO A;  1IQJ L;  2J38 B;  1G2L B;  2P3F L;  4Z6A L;  3EGF A;  1G1S A;  5COX A;  1HT8 A;  2B7D L;  1URK A;  2UWP B;  2VWO L;  2BOU A;  1DQB A;  4O1Z A;  2J95 B;  1BF9 A;  3CS7 L;  1F7E A;  5L2Y L;  1DVA L;  2Q1J B;  3ENS A;  4YZU B;  1UZP A;  1V3X B;  3TGF A;  1G1T A;  4NA9 L;  1FF7 A;  3SW2 A;  3HPT A;  4Y7A B;  1ATA A;  1SZB A;  2Y38 A;  1WU1 B;  4YT6 L;  2PHB B;  2P26 A;  2F9B L;  1Z6E L;  4A7I A;  2VVV L;  3MQE A;  1HJ7 A;  3F6U L;  1YUK B;  1PRH A;  1PGE A;  2P93 L;  1NFW B;  4C16 A;  2K2S B;  1B9W A;  2MGR A;  4E1G A;  2Y80 B;  1EMO A;  3M36 L;  2OYE P;  3N8Y B;  1HAE A;  1LQD A;  3Q3K B;  1OB1 C;  2GD4 A;  1IOE L;  5KIR A;  3KRK A;  2Y5F L;  3TBD A;  1G1Q A;  1HX2 A;  1IGZ A;  4D90 A;  1MQ6 L;  1F0S B;  3GCX E;  3LC5 B;  3HO4 A;  1IQI L;  1YGC L;  4Y79 B;  1CCF A;  3OLU A;  4ISI L;  1TOZ A;  4OTJ A;  1HCG B;  2XC5 L;  2J2U B;  1C5M F;  5CIS A;  4RRX A;  2FLR L;  1EGF A;  4MMZ B;  2XC0 L;  5I46 L;  1CVW L;  1J9C L;  2VVU L;  1YUF A;  2I9A A;  1IQE L;  4M11 A;  1NT0 A;  1NFY B;  1LMJ A;  4Z0K B;  5JBC E;  2NPR A;  3QMO A;  5IKT A;  1WHE A;  3NTG A;  2W86 A;  3N8W A;  4D0E A;  5F19 A;  2KV4 A;  2KL7 A;  5IKV A;  5JW1 A;  3C9A C;  1IVO C;  2WPI E;  1HRF A;  4ZH8 B;  4FM5 A;  3U7U G;  2G00 L;  2XBW L;  3KQD L;  1LPG A;  5L2Z L;  2RHP A;  4BXW A;  4JYU L;  2BQW A;  2EI6 B;  1G2M B;  3TH3 L;  1Q4G A;  2WPL E;  5EGM B;  2WPJ E;  4X8T L;  5K0H B;  3IIT B;  1N1I A;  1DX5 I;  1NPE B;  1PFX L;  1FSB A;  4NGA L;  1MOX C;  1EBV A;  3QCW A;  1EAI C;  3P5B L;  3V64 C;  1IJQ A;  1EMN A;  6COX A;  2WYG B;  3LN1 A;  1TPG A;  3HS6 A;  5JB9 E;  2XBX L;  1ZAQ A;  1EQH A;  3Q7D A;  4Y76 B;  3R05 A;  1O5D L;  1KSN B;  3N8Y A;  1W8B L;  1QFK L;  5CKQ A;  2P28 B;  2FZZ L;  4NG9 L;  4ZXX L;  3HO5 A;  2VWN L;  3KCG L;  2WYJ B;  2BO2 A;  4JYV L;  1NFU B;  1NQL B;  2JKH L;  1IQK L;  1I0U A;  2CJI B;  2P3T A;  4JZD L;  4X8S L;  1ATB A;  4D0F A;  4JZE L;  2KB9 A;  2P3F N;  2P95 L;  4Y7B B;  3N8V A;  1FAX L;  2BMG A;  2DDU A;  4Y6D B;  3U73 A;  4ZHA B;  1HZ8 A;  2H9E L;  2BQ7 A;  2ADX A;  1IQH L;  5F1A A;  3SOB B;  4CUD A;  3POY A;  1RFN B;  1UZQ A;  1IQL L;  1U8C B;  1JBU L;  1ATE A;  3N8Z A;  4JZF L;  3TK5 B;  5FDQ A;  2J4I B;  3KQC L;  3ZYI B;  5JBB E;  1P0S L;  3LC3 B;  5JBA E;  3LAQ A;  4BDW A;  3LN0 A;  2XBY L;  4O02 B;  1EPJ A;  3V65 B;  4RRY A;  1WHF A;  1F0R B;  2BZ6 L;  4MMY B;  5JB8 E;  4LOR A;  2M74 A;  1LPK A;  3KQB L;  1APO A;  3CEN L;  2W3K B;  2RNL A;  2Y81 B;  3N8X A;  1EPI A;  5CKN A;  1KLI L;  3BPS E;  4CUF A;  3HS7 A;  1M1X B;  1HT5 A;  1F7M A;  3ZYG A;  3SOV A;  4BXS A;  3OLT A;  4CSY A;  4MMX B;  1FE2 A;  2BOK L;  4ZAE B;  2J34 B;  5JVZ A;  4TGF A;  2BOH A;  1GK5 A;  1ADX A;  3NJP C;  1EZQ B;  3NT1 A;  2OYU P;  2FLB L;  3HO3 A;  2P94 L;  5KN5 C;  3LTF B;  3TZI A;  4BTT A;  1ATD A;  4COX A;  2EI8 B;  1FFM A;  3FFG L;  1PTH A;  2EI7 B;  3IJE B;  1FJS L;  5IKR A;  4X8V L;  2I9B A;  2MGP A;  2UWO B;  4M10 A;  3N8W B;  4ZXY L;  3KK6 A;  5L30 L;  1UZJ A;  3BT1 A;  1CCV A;  2WG4 B;  1NFX B;  4BTU A;  4RRZ A;  2VVC K;  2MHP A;  1COU A;  1AUT L;  2FD6 A;  1JV2 B;  2PR3 B;  2WPK E;  1DIY A;  4Y71 B;  4BDX A;  1EQG A;  2AYL A;  3FCS B;  1L3Y A;  2XBV L;  1X7A L;  1IQN L;  1HAF A;  2D1J B;  4PH9 A;  4Z0L A;  2Y5H L;  3GIS X;  2W2P E;  1HRE A;  3FBY A;  2WG3 C;  1KLJ L;  3ASI A;  2P16 L;  5JVY A;  3PGH A;  5E8D A;  2K2T A;  4AQT A;  2J94 B;  3LTG D;  1EPH A;  2PUQ L;  1G1R A;  4BTI A;  1K36 A;  2Y82 B;  2W2N E;  3NTB A;  1PXX A;  3CFW A;  3H5C B;  3LIW B;  3HS5 A;  1YUG A;  2P3U A;  3TK6 B;  4YT7 L;  2Y5G L;  4RRW A;  3GCW E;  2Y7X B;  4RS0 A;  2VH0 B;  1APQ A;  4RUT A;  1IQF L;  2BQ6 A;  1JL9 A;  1A3P A;  2WPH E;  4XLW A;  2W2Q E;  1LPZ A;  1XFE A;  4LMF A;  1IOX A;  1L5G B;  2WFX B;  2W3I B;  3ELA L;  2FLG A;  1MQ5 L;  1IQG L; 
#chains in the Genus database with same CATH topology
 1W7X L;  1K37 A;  3CA7 A;  1EPG A;  5IKQ A;  4CUE A;  4OTY A;  5CKM A;  3F1S B;  2VWM K;  2YGQ A;  2RA0 L;  2VJ3 A;  3ZYJ B;  3RR3 A;  2YGP A;  2W26 B;  1TLE A;  2WFT A;  4XL1 A;  3MDL A;  2BSF A;  2Y7Z B;  3DEM A;  2TGF A;  4XBM A;  1XKB A;  1U67 A;  1CQE A;  1CX2 A;  1FAK L;  1YO8 A;  1UZK A;  1CVU A;  4X8U L;  2YGO A;  3M37 L;  2W2O E;  1NZI A;  2XC4 L;  2VWL L;  1DDX A;  1KIG L;  1IGX A;  1IQM L;  4G1M B;  1IP0 A;  2WPM E;  3QH0 A;  3BT2 A;  2BOX A;  3KQE L;  2UWL B;  3SOQ A;  1N7D A;  1Z6C A;  1XDT R;  2W2M E;  4ISH L;  1CEJ A;  1P9J A;  1XKA L;  2VH6 B;  3K9X A;  3KL6 B;  1KLO A;  1IQJ L;  2J38 B;  1G2L B;  2P3F L;  4Z6A L;  3EGF A;  1G1S A;  5COX A;  1HT8 A;  2B7D L;  1URK A;  2UWP B;  2VWO L;  2BOU A;  1DQB A;  4O1Z A;  2J95 B;  1BF9 A;  3CS7 L;  1F7E A;  5L2Y L;  1DVA L;  2Q1J B;  3ENS A;  4YZU B;  1UZP A;  1V3X B;  3TGF A;  1G1T A;  4NA9 L;  1FF7 A;  3SW2 A;  3HPT A;  4Y7A B;  1ATA A;  1SZB A;  2WZP P;  2Y38 A;  1WU1 B;  4YT6 L;  2PHB B;  2P26 A;  2F9B L;  1Z6E L;  4A7I A;  2VVV L;  3MQE A;  1V1I A;  1HJ7 A;  3F6U L;  1YUK B;  1PRH A;  1PGE A;  2P93 L;  1NFW B;  4C16 A;  2K2S B;  1B9W A;  2MGR A;  4E1G A;  2Y80 B;  1EMO A;  3M36 L;  2OYE P;  3N8Y B;  1HAE A;  1QIU A;  1LQD A;  3Q3K B;  1OB1 C;  2GD4 A;  1IOE L;  5KIR A;  3KRK A;  2Y5F L;  3TBD A;  1G1Q A;  1HX2 A;  2BT8 A;  1IGZ A;  4D90 A;  1MQ6 L;  1F0S B;  3GCX E;  3LC5 B;  3HO4 A;  1IQI L;  1YGC L;  4Y79 B;  1CCF A;  3OLU A;  4ISI L;  1TOZ A;  4OTJ A;  1HCG B;  2XC5 L;  2J2U B;  1C5M F;  5CIS A;  4RRX A;  2FLR L;  1EGF A;  4MMZ B;  2XC0 L;  5I46 L;  1CVW L;  1J9C L;  2VVU L;  1YUF A;  2I9A A;  1IQE L;  4M11 A;  1NT0 A;  1NFY B;  1LMJ A;  4Z0K B;  5JBC E;  1LK9 A;  2NPR A;  3QMO A;  5IKT A;  1WHE A;  3NTG A;  2W86 A;  3N8W A;  4D0E A;  5F19 A;  2KV4 A;  2KL7 A;  5IKV A;  2VRS A;  5JW1 A;  3C9A C;  1IVO C;  2WPI E;  4A94 C;  1HRF A;  4ZH8 B;  2KNI A;  4FM5 A;  3U7U G;  2G00 L;  2XBW L;  3KQD L;  1LPG A;  5L2Z L;  2RHP A;  4BXW A;  4JYU L;  2BQW A;  2EI6 B;  1G2M B;  3TH3 L;  1V1H A;  1Q4G A;  2WPL E;  5EGM B;  2WPJ E;  4X8T L;  5K0H B;  2BT7 A;  3IIT B;  1N1I A;  1DX5 I;  1NPE B;  1PFX L;  1FSB A;  4NGA L;  1MOX C;  1EBV A;  3QCW A;  1EAI C;  3P5B L;  3V64 C;  1IJQ A;  1EMN A;  6COX A;  2WYG B;  3LN1 A;  1TPG A;  3HS6 A;  5JB9 E;  2XBX L;  1ZAQ A;  1EQH A;  3Q7D A;  4Y76 B;  3R05 A;  1O5D L;  1KSN B;  3N8Y A;  1W8B L;  1QFK L;  5CKQ A;  2P28 B;  2FZZ L;  4NG9 L;  4ZXX L;  3HO5 A;  2VWN L;  3KCG L;  2WYJ B;  2BO2 A;  4JYV L;  1NFU B;  1NQL B;  2JKH L;  1IQK L;  1I0U A;  2CJI B;  2P3T A;  4JZD L;  4X8S L;  1ATB A;  4D0F A;  3S6X A;  4JZE L;  2KB9 A;  2P3F N;  2P95 L;  4Y7B B;  3N8V A;  1FAX L;  2BMG A;  2DDU A;  4Y6D B;  3U73 A;  4ZHA B;  1HZ8 A;  2H9E L;  1LMM A;  2BQ7 A;  2ADX A;  1IQH L;  5F1A A;  3SOB B;  4CUD A;  3POY A;  1RFN B;  1UZQ A;  1IQL L;  1U8C B;  1JBU L;  1ATE A;  3N8Z A;  4JZF L;  3TK5 B;  5FDQ A;  2J4I B;  3KQC L;  3ZYI B;  2HOX A;  5JBB E;  1P0S L;  3LC3 B;  5JBA E;  3LAQ A;  4BDW A;  3LN0 A;  2XBY L;  4O02 B;  1EPJ A;  3V65 B;  4RRY A;  1WHF A;  1F0R B;  2BZ6 L;  4MMY B;  5JB8 E;  4LOR A;  2M74 A;  1LPK A;  3KQB L;  1APO A;  3CEN L;  2W3K B;  2RNL A;  2Y81 B;  3N8X A;  1EPI A;  5CKN A;  4GU3 A;  1KLI L;  3BPS E;  4CUF A;  3HS7 A;  1M1X B;  1HT5 A;  1F7M A;  3ZYG A;  2JJL A;  3SOV A;  4BXS A;  3OLT A;  4CSY A;  4MMX B;  1FE2 A;  2BOK L;  4ZAE B;  2J34 B;  5JVZ A;  4TGF A;  2BOH A;  2HOR A;  1GK5 A;  1ADX A;  3NJP C;  1EZQ B;  3NT1 A;  2OYU P;  2FLB L;  3HO3 A;  2P94 L;  5KN5 C;  3LTF B;  3TZI A;  4BTT A;  1ATD A;  4COX A;  2EI8 B;  1FFM A;  3FFG L;  1PTH A;  2EI7 B;  3IJE B;  1FJS L;  5IKR A;  4X8V L;  2I9B A;  2MGP A;  2UWO B;  4M10 A;  3N8W B;  4ZXY L;  3KK6 A;  5L30 L;  1UZJ A;  3BT1 A;  1CCV A;  2WG4 B;  1NFX B;  4BTU A;  4RRZ A;  2VVC K;  2MHP A;  1COU A;  1AUT L;  2FD6 A;  1JV2 B;  2PR3 B;  2WPK E;  1DIY A;  4Y71 B;  4GU4 A;  1EQG A;  2AYL A;  4BDX A;  3FCS B;  1L3Y A;  2XBV L;  1X7A L;  1IQN L;  1HAF A;  2D1J B;  4PH9 A;  4Z0L A;  2Y5H L;  3GIS X;  2W2P E;  1HRE A;  3FBY A;  2WG3 C;  1KLJ L;  3ASI A;  2P16 L;  5JVY A;  3PGH A;  5E8D A;  2K2T A;  4AQT A;  2J94 B;  3LTG D;  1EPH A;  2PUQ L;  1G1R A;  4BTI A;  1K36 A;  2Y82 B;  2W2N E;  3NTB A;  1PXX A;  3CFW A;  3H5C B;  2H9E C;  3LIW B;  3HS5 A;  1YUG A;  2P3U A;  3TK6 B;  4YT7 L;  2Y5G L;  4RRW A;  3GCW E;  2Y7X B;  4RS0 A;  2VH0 B;  1APQ A;  4RUT A;  1IQF L;  2BQ6 A;  1JL9 A;  1A3P A;  2WPH E;  4XLW A;  2W2Q E;  1LPZ A;  1KKE A;  1XFE A;  4LMF A;  1IOX A;  1L5G B;  2WFX B;  2W3I B;  3ELA L;  2FLG A;  1MQ5 L;  1IQG L; 
#chains in the Genus database with same CATH homology
 1W7X L;  1K37 A;  3CA7 A;  1EPG A;  5IKQ A;  4CUE A;  4OTY A;  5CKM A;  3F1S B;  2VWM K;  2YGQ A;  2RA0 L;  2VJ3 A;  3ZYJ B;  3RR3 A;  2YGP A;  2W26 B;  1TLE A;  2WFT A;  4XL1 A;  3MDL A;  2Y7Z B;  3DEM A;  2TGF A;  4XBM A;  1XKB A;  1U67 A;  1CQE A;  1CX2 A;  1FAK L;  1YO8 A;  1UZK A;  1CVU A;  4X8U L;  2YGO A;  3M37 L;  2W2O E;  1NZI A;  2XC4 L;  2VWL L;  1DDX A;  1KIG L;  1IGX A;  1IQM L;  4G1M B;  1IP0 A;  2WPM E;  3QH0 A;  3BT2 A;  2BOX A;  3KQE L;  2UWL B;  3SOQ A;  1N7D A;  1Z6C A;  1XDT R;  2W2M E;  4ISH L;  1CEJ A;  1P9J A;  1XKA L;  2VH6 B;  3K9X A;  3KL6 B;  1KLO A;  1IQJ L;  2J38 B;  1G2L B;  2P3F L;  4Z6A L;  3EGF A;  1G1S A;  5COX A;  1HT8 A;  2B7D L;  1URK A;  2UWP B;  2VWO L;  2BOU A;  1DQB A;  4O1Z A;  2J95 B;  1BF9 A;  3CS7 L;  1F7E A;  5L2Y L;  1DVA L;  2Q1J B;  3ENS A;  4YZU B;  1UZP A;  1V3X B;  3TGF A;  1G1T A;  4NA9 L;  1FF7 A;  3SW2 A;  3HPT A;  4Y7A B;  1ATA A;  1SZB A;  2WZP P;  2Y38 A;  1WU1 B;  4YT6 L;  2PHB B;  2P26 A;  2F9B L;  1Z6E L;  4A7I A;  2VVV L;  3MQE A;  1HJ7 A;  3F6U L;  1YUK B;  1PRH A;  1PGE A;  2P93 L;  1NFW B;  4C16 A;  2K2S B;  1B9W A;  2MGR A;  4E1G A;  2Y80 B;  1EMO A;  3M36 L;  2OYE P;  3N8Y B;  1HAE A;  1LQD A;  3Q3K B;  1OB1 C;  2GD4 A;  1IOE L;  5KIR A;  3KRK A;  2Y5F L;  3TBD A;  1G1Q A;  1HX2 A;  1IGZ A;  4D90 A;  1MQ6 L;  1F0S B;  3GCX E;  3LC5 B;  3HO4 A;  1IQI L;  1YGC L;  4Y79 B;  1CCF A;  3OLU A;  4ISI L;  1TOZ A;  4OTJ A;  1HCG B;  2XC5 L;  2J2U B;  1C5M F;  5CIS A;  4RRX A;  2FLR L;  1EGF A;  4MMZ B;  2XC0 L;  5I46 L;  1CVW L;  1J9C L;  2VVU L;  1YUF A;  2I9A A;  1IQE L;  4M11 A;  1NT0 A;  1NFY B;  1LMJ A;  4Z0K B;  5JBC E;  2NPR A;  3QMO A;  5IKT A;  1WHE A;  3NTG A;  2W86 A;  3N8W A;  4D0E A;  5F19 A;  2KV4 A;  2KL7 A;  5IKV A;  5JW1 A;  3C9A C;  1IVO C;  2WPI E;  4A94 C;  1HRF A;  4ZH8 B;  2KNI A;  4FM5 A;  3U7U G;  2G00 L;  2XBW L;  3KQD L;  1LPG A;  5L2Z L;  2RHP A;  4BXW A;  4JYU L;  2BQW A;  2EI6 B;  1G2M B;  3TH3 L;  1Q4G A;  2WPL E;  5EGM B;  2WPJ E;  4X8T L;  5K0H B;  3IIT B;  1N1I A;  1DX5 I;  1NPE B;  1PFX L;  1FSB A;  4NGA L;  1MOX C;  1EBV A;  3QCW A;  1EAI C;  3P5B L;  3V64 C;  1IJQ A;  1EMN A;  6COX A;  2WYG B;  3LN1 A;  1TPG A;  3HS6 A;  5JB9 E;  2XBX L;  1ZAQ A;  1EQH A;  3Q7D A;  4Y76 B;  3R05 A;  1O5D L;  1KSN B;  3N8Y A;  1W8B L;  1QFK L;  5CKQ A;  2P28 B;  2FZZ L;  4NG9 L;  4ZXX L;  3HO5 A;  2VWN L;  3KCG L;  2WYJ B;  2BO2 A;  4JYV L;  1NFU B;  1NQL B;  2JKH L;  1IQK L;  1I0U A;  2CJI B;  2P3T A;  4JZD L;  4X8S L;  1ATB A;  4D0F A;  3S6X A;  4JZE L;  2KB9 A;  2P3F N;  2P95 L;  4Y7B B;  3N8V A;  1FAX L;  2BMG A;  2DDU A;  4Y6D B;  3U73 A;  4ZHA B;  1HZ8 A;  2H9E L;  1LMM A;  2BQ7 A;  2ADX A;  1IQH L;  5F1A A;  3SOB B;  4CUD A;  3POY A;  1RFN B;  1UZQ A;  1IQL L;  1U8C B;  1JBU L;  1ATE A;  3N8Z A;  4JZF L;  3TK5 B;  5FDQ A;  2J4I B;  3KQC L;  3ZYI B;  5JBB E;  1P0S L;  3LC3 B;  5JBA E;  3LAQ A;  4BDW A;  3LN0 A;  2XBY L;  4O02 B;  1EPJ A;  3V65 B;  4RRY A;  1WHF A;  1F0R B;  2BZ6 L;  4MMY B;  5JB8 E;  4LOR A;  2M74 A;  1LPK A;  3KQB L;  1APO A;  3CEN L;  2W3K B;  2RNL A;  2Y81 B;  3N8X A;  1EPI A;  5CKN A;  1KLI L;  3BPS E;  4CUF A;  3HS7 A;  1M1X B;  1HT5 A;  1F7M A;  3ZYG A;  3SOV A;  4BXS A;  3OLT A;  4CSY A;  4MMX B;  1FE2 A;  2BOK L;  4ZAE B;  2J34 B;  5JVZ A;  4TGF A;  2BOH A;  1GK5 A;  1ADX A;  3NJP C;  1EZQ B;  3NT1 A;  2OYU P;  2FLB L;  3HO3 A;  2P94 L;  5KN5 C;  3LTF B;  3TZI A;  4BTT A;  1ATD A;  4COX A;  2EI8 B;  1FFM A;  3FFG L;  1PTH A;  2EI7 B;  3IJE B;  1FJS L;  5IKR A;  4X8V L;  2I9B A;  2MGP A;  2UWO B;  4M10 A;  3N8W B;  4ZXY L;  3KK6 A;  5L30 L;  1UZJ A;  3BT1 A;  1CCV A;  2WG4 B;  1NFX B;  4BTU A;  4RRZ A;  2VVC K;  2MHP A;  1COU A;  1AUT L;  2FD6 A;  1JV2 B;  2PR3 B;  2WPK E;  1DIY A;  4Y71 B;  4BDX A;  1EQG A;  2AYL A;  3FCS B;  1L3Y A;  2XBV L;  1X7A L;  1IQN L;  1HAF A;  2D1J B;  4PH9 A;  4Z0L A;  2Y5H L;  3GIS X;  2W2P E;  1HRE A;  3FBY A;  2WG3 C;  1KLJ L;  3ASI A;  2P16 L;  5JVY A;  3PGH A;  5E8D A;  2K2T A;  4AQT A;  2J94 B;  3LTG D;  1EPH A;  2PUQ L;  1G1R A;  4BTI A;  1K36 A;  2Y82 B;  2W2N E;  3NTB A;  1PXX A;  3CFW A;  3H5C B;  2H9E C;  3LIW B;  3HS5 A;  1YUG A;  2P3U A;  3TK6 B;  4YT7 L;  2Y5G L;  4RRW A;  3GCW E;  2Y7X B;  4RS0 A;  2VH0 B;  1APQ A;  4RUT A;  1IQF L;  2BQ6 A;  1JL9 A;  1A3P A;  2WPH E;  4XLW A;  2W2Q E;  1LPZ A;  1XFE A;  4LMF A;  1IOX A;  1L5G B;  2WFX B;  2W3I B;  3ELA L;  2FLG A;  1MQ5 L;  1IQG L; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...