2G00L

Factor xa in complex with the inhibitor 3-(6-(2'-((dimethylamino)methyl)-4-biphenylyl)-7-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1h-pyrazolo[3,4-c]pyridin-1-yl)benzamide
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Coagulation factor X
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2006-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2g00L00
1JL9A 2Y5HL 3GCWE 2D1JB 1LPGA 2P16L 4YZUB 2J94B 4COXA 1NFXB 2Y5FL 1IQEL 4MMXB 1P0SL 1CQEA 3LTFB 1YUGA 3N8XA 3LN1A 3CENL 3PGHA 3TK5B 1ATEA 4A7IA 2KL7A 4X8VL 2H9EL 5L2ZL 1NZIA 4ZXYL 5CKQA 1UZQA 1XDTR 2W2PE 5L2YL 3HO3A 1F7MA 3V64C 2XBVL 2FLBL 2WYJB 1HT8A 1CVWL 1W8BL 2WG3C 2ADXA 2BZ6L 1DQBA 4ZAEB 3F6UL 5IKTA 1KLOA 4RRZA 1G1SA 1IQNL 5K0HB 1EMNA 1EPIA 1A3PA 1FFMA 3N8VA 2XC4L 1U67A 1B9WA 1HT5A 1WHFA 1KIGL 3NTGA 4X8SL 1OB1C 2P28B 5JBAE 4E1GA 1IQLL 3M36L 1Z6CA 3QH0A 3K9XA 4M11A 1EPHA 3ZYGA 1L3YA 2K2SB 4Z0LA 2P94L 3KL6B 1IGZA 2WYGB 5JVYA 1COUA 1NFYB 2UWOB 2I9BA 4Z0KB 1L5GB 3N8YB 3ASIA 4X8TL 4ZHAB 4RUTA 3SOBB 5IKVA 2I9AA 4OTJA 1PXXA 4Y76B 3ZYIB 2W2OE 1EPGA 1LQDA 1IQGL 3SW2A 4RRWA 2W3IB 3F1SB 1XKBA 2P93L 5CISA 1IOXA 2XBYL 1LMJA 2WPLE 4Z6AL 4TGFA 4RRXA 3TZIA 1NPEB 3N8WA 3SOQA 1QFKL 1W7XL 3BPSE 2Y7XB 1F0RB 3KQCL 3IJEB 2B7DL 5IKQA 1NT0A 3M37L 1KSNB 3DEMA 5FDQA 2G00L 2NPRA 1KLJL 1CX2A 2WPJE 1DX5I 3HS5A 2W26B 1CEJA 1RFNB 2FZZL 3CA7A 2BQ6A 1WU1B 3GCXE 4Y6DB 5L30L 1PFXL 2BOXA 5I46L 1ADXA 3LC5B 2VWMK 3FFGL 1DVAL 1EQGA 2EI8B 2P3UA 4Y7BB 4BTIA 4RS0A 3HS6A 4YT6L 1HZ8A 1K36A 1HX2A 3TH3L 3P5BL 3HO4A 4D90A 1F0SB 2PR3B 3C9AC 3GISX 5E8DA 3H5CB 4XL1A 2RA0L 4O02B 3KK6A 5F19A 3NTBA 4BXSA 1EMOA 1G2LB 3CFWA 2BQWA 2P95L 2VH6B 1LPKA 4O1ZA 1XKAL 1IQHL 3LTGD 1HJ7A 2MGPA 2VWOL 2OYUP 4CUEA 1URKA 4BXWA 1X7AL 3MDLA 3R05A 1JBUL 3U7UG 2Q1JB 2W86A 3N8YA 2MGRA 1DDXA 4JZFL 4BTTA 1CCVA 2M74A 2TGFA 2VWLL 1PRHA 2WPIE 1PGEA 2CJIB 1SZBA 1HAFA 2WFTA 5CKNA 3ZYJB 4RRYA 2FLGA 2P3FL 4BDWA 1FAKL 2FLRL 4D0EA 1WHEA 3FCSB 1IQIL 1J9CL 4JZEL 3KQBL 2W2ME 2BOHA 2Y81B 4BDXA 4LORA 2J2UB 4G1MB 3ELAL 1YUKB 2BOUA 3TGFA 2YGPA 4ZXXL 3TK6B 1ATDA 5JBBE 2BMGA 1PTHA 3LN0A 3LC3B 2P3FN 1TPGA 4CUFA 1EAIC 1FJSL 1U8CB 4Y79B 1NFUB 2UWLB 4X8UL 6COXA 1IOEL 2Y5GL 3TBDA 2WFXB 4JYVL 4FM5A 1IQJL 2AYLA 1UZKA 3N8WB 3N8ZA 2WG4B 1APOA 3KQDL 4MMYB 4C16A 1IGXA 1TOZA 1ATAA 2J38B 3HO5A 3OLTA 1NQLB 5JB8E 4ISHL 3LIWB 1K37A 3Q3KB 3KCGL 2XBWL 1TLEA 4JZDL 1APQA 3NJPC 3IITB 5JW1A 3OLUA 2W2QE 3KRKA 1AUTL 2VVUL 1G2MB 1Q4GA 1LPZA 1FAXL 3ENSA 1JV2B 2XBXL 1KLIL 1G1TA 4LMFA 2VWNL 2MHPA 2F9BL 2J34B 4ZH8B 1FF7A 1EGFA 5KN5C 1CCFA 4PH9A 2UWPB 3CS7L 1IVOC 1IQML 2VVCK 4Y71B 2WPKE 1FE2A 1YO8A 3V65B 2JKHL 4NA9L 4NG9L 3BT2A 2P3TA 2BQ7A 2W2NE 3Q7DA 4MMZB 4Y7AB 1FSBA 1IQKL 1ATBA 3FBYA 4M10A 1YUFA 2EI7B 3QCWA 4XBMA 1IQFL 1ZAQA 5F1AA 1HRFA 5EGMB 4YT7L 2EI6B 2P26A 4D0FA 1V3XB 2VH0B 2Y82B 1G1QA 2W3KB 2XC0L 2YGOA 4CSYA 1C5MF 2WPHE 1F7EA 3KQEL 3HPTA 1I0UA 1M1XB 3SOVA 1XFEA 2KV4A 2WPME 3QMOA 5IKRA 1UZJA 4ISIL 2XC5L 5JBCE 3EGFA 1EPJA 1YGCL 1N1IA 1MOXC 1UZPA 4BTUA 3U73A 1GK5A 2DDUA 4CUDA 1BF9A 3NT1A 2PUQL 2OYEP 2VVVL 2BOKL 5JVZA 3POYA 2J95B 2Y7ZB 1MQ5L 1N7DA 5JB9E 4XLWA 1HCGB 1DIYA 5KIRA 2Y80B 1EBVA 3MQEA 1EZQB 3BT1A 1CVUA 2BO2A 2Y38A 2FD6A 4NGAL 2KB9A 4OTYA 1O5DL 2VJ3A 1HAEA 1NFWB 3HS7A 1Z6EL 2RHPA 1EQHA 1P9JA 2K2TA 3RR3A 5CKMA 1G1RA 2RNLA 1IJQA 4AQTA 2GD4A 3LAQA 1MQ6L 2J4IB 4JYUL 2PHBB 5COXA 1HREA 1IP0A
chains in the Genus database with same CATH superfamily
1JL9A 2Y5HL 3GCWE 2D1JB 1LPGA 2P16L 4YZUB 2J94B 4COXA 1NFXB 2HOXA 2Y5FL 1IQEL 4MMXB 1P0SL 1CQEA 3LTFB 1YUGA 3N8XA 3LN1A 2BT7A 3CENL 3PGHA 3TK5B 1ATEA 4A7IA 2KL7A 4X8VL 2H9EL 5L2ZL 1NZIA 4ZXYL 5CKQA 1UZQA 1XDTR 2W2PE 5L2YL 3HO3A 1F7MA 3V64C 2XBVL 2FLBL 2WYJB 1HT8A 1CVWL 1W8BL 2WG3C 2ADXA 2BZ6L 1DQBA 4ZAEB 3F6UL 5IKTA 1KLOA 4RRZA 1G1SA 1IQNL 5K0HB 1EMNA 1EPIA 1A3PA 1FFMA 3N8VA 2XC4L 1U67A 1B9WA 1HT5A 1WHFA 1KIGL 3NTGA 4X8SL 1OB1C 2P28B 5JBAE 4E1GA 1IQLL 3M36L 1Z6CA 3QH0A 3K9XA 4M11A 1EPHA 3ZYGA 1LMMA 1L3YA 2K2SB 4GU4A 4Z0LA 2HORA 2P94L 3KL6B 1IGZA 2WYGB 5JVYA 1COUA 1NFYB 2UWOB 2I9BA 4Z0KB 1L5GB 3N8YB 3ASIA 4X8TL 4ZHAB 4RUTA 3SOBB 5IKVA 2BSFA 2I9AA 4OTJA 1PXXA 4Y76B 3ZYIB 2W2OE 1EPGA 1LQDA 1IQGL 3SW2A 4RRWA 2W3IB 3F1SB 1XKBA 2P93L 5CISA 1IOXA 2XBYL 1LMJA 2WPLE 4Z6AL 4TGFA 4RRXA 3TZIA 1NPEB 2JJLA 3N8WA 3SOQA 2H9EC 1QFKL 1W7XL 3BPSE 2Y7XB 1F0RB 3KQCL 3IJEB 2B7DL 5IKQA 1NT0A 3M37L 1KSNB 3DEMA 5FDQA 2WZPP 2G00L 2NPRA 1KLJL 1CX2A 2WPJE 1DX5I 3HS5A 2W26B 1CEJA 1RFNB 2FZZL 3CA7A 2BQ6A 1WU1B 3GCXE 4Y6DB 5L30L 1PFXL 2BOXA 5I46L 1ADXA 3LC5B 2VWMK 1LK9A 3FFGL 1DVAL 1EQGA 2EI8B 2P3UA 4Y7BB 4BTIA 4RS0A 3HS6A 4YT6L 1HZ8A 1K36A 1HX2A 3TH3L 3P5BL 3HO4A 4D90A 1F0SB 2PR3B 3C9AC 3GISX 5E8DA 3H5CB 4XL1A 2RA0L 4O02B 3KK6A 5F19A 3NTBA 4BXSA 1EMOA 1G2LB 3CFWA 2BQWA 2P95L 2VH6B 1LPKA 4O1ZA 1XKAL 1IQHL 3LTGD 1HJ7A 2MGPA 2VWOL 2OYUP 4CUEA 1URKA 4BXWA 1X7AL 3MDLA 3R05A 1JBUL 3U7UG 4A94C 2Q1JB 2W86A 3N8YA 2MGRA 1DDXA 4JZFL 4BTTA 1CCVA 2M74A 2VRSA 2TGFA 2VWLL 1PRHA 2WPIE 1PGEA 2CJIB 1SZBA 1HAFA 2WFTA 5CKNA 3ZYJB 4RRYA 2FLGA 2P3FL 2YGQA 4BDWA 1FAKL 2FLRL 4D0EA 2KNIA 1WHEA 3FCSB 1IQIL 1J9CL 4JZEL 3KQBL 2W2ME 2BOHA 2Y81B 4BDXA 4LORA 2J2UB 4G1MB 3ELAL 1YUKB 2BOUA 3TGFA 2YGPA 4ZXXL 3TK6B 1ATDA 5JBBE 2BMGA 1PTHA 3LN0A 3LC3B 2P3FN 1TPGA 4CUFA 1EAIC 1FJSL 1U8CB 4Y79B 1NFUB 2UWLB 4X8UL 6COXA 1IOEL 2Y5GL 3TBDA 2WFXB 4JYVL 4FM5A 1IQJL 2AYLA 1UZKA 3N8WB 3N8ZA 2WG4B 1APOA 3KQDL 4MMYB 4C16A 1IGXA 1KKEA 1TOZA 1ATAA 2J38B 3HO5A 3OLTA 1NQLB 5JB8E 4ISHL 1V1IA 3LIWB 1K37A 3Q3KB 3KCGL 2XBWL 1TLEA 4JZDL 1APQA 3NJPC 3IITB 5JW1A 3OLUA 2W2QE 3KRKA 1AUTL 4GU3A 2VVUL 1G2MB 1Q4GA 1LPZA 1FAXL 3ENSA 1JV2B 2XBXL 1KLIL 1G1TA 4LMFA 3S6XA 2VWNL 2MHPA 2F9BL 2J34B 4ZH8B 1FF7A 1EGFA 5KN5C 1CCFA 4PH9A 2UWPB 3CS7L 1IVOC 1IQML 2VVCK 4Y71B 2WPKE 1FE2A 1YO8A 3V65B 2JKHL 4NA9L 4NG9L 3BT2A 2P3TA 2BQ7A 2W2NE 3Q7DA 4MMZB 4Y7AB 1FSBA 1IQKL 1ATBA 3FBYA 4M10A 1YUFA 2EI7B 3QCWA 4XBMA 1IQFL 1ZAQA 5F1AA 1HRFA 5EGMB 4YT7L 2EI6B 2P26A 4D0FA 1V3XB 2VH0B 2Y82B 1G1QA 2W3KB 2XC0L 2YGOA 4CSYA 1C5MF 2WPHE 1F7EA 3KQEL 3HPTA 1I0UA 1M1XB 3SOVA 1XFEA 2KV4A 1V1HA 2WPME 3QMOA 5IKRA 1UZJA 4ISIL 2XC5L 5JBCE 3EGFA 1EPJA 1YGCL 1N1IA 1MOXC 1UZPA 4BTUA 3U73A 1GK5A 2DDUA 4CUDA 1BF9A 3NT1A 2PUQL 2OYEP 2VVVL 2BT8A 2BOKL 5JVZA 3POYA 2J95B 2Y7ZB 1MQ5L 1N7DA 5JB9E 4XLWA 1HCGB 1DIYA 5KIRA 2Y80B 1EBVA 3MQEA 1EZQB 3BT1A 1CVUA 2BO2A 2Y38A 2FD6A 4NGAL 2KB9A 4OTYA 1O5DL 2VJ3A 1HAEA 1NFWB 3HS7A 1Z6EL 2RHPA 1EQHA 1P9JA 2K2TA 3RR3A 5CKMA 1G1RA 2RNLA 1IJQA 4AQTA 2GD4A 1QIUA 3LAQA 1MQ6L 2J4IB 4JYUL 2PHBB 5COXA 1HREA 1IP0A
chains in the Genus database with same CATH topology
1JL9A 2Y5HL 3GCWE 2D1JB 1LPGA 2P16L 4YZUB 2J94B 4COXA 1NFXB 2Y5FL 1IQEL 4MMXB 1P0SL 1CQEA 3LTFB 1YUGA 3N8XA 3LN1A 3CENL 3PGHA 3TK5B 1ATEA 4A7IA 2KL7A 4X8VL 2H9EL 5L2ZL 1NZIA 4ZXYL 5CKQA 1UZQA 1XDTR 2W2PE 5L2YL 3HO3A 1F7MA 3V64C 2XBVL 2FLBL 2WYJB 1HT8A 1CVWL 1W8BL 2WG3C 2ADXA 2BZ6L 1DQBA 4ZAEB 3F6UL 5IKTA 1KLOA 4RRZA 1G1SA 1IQNL 5K0HB 1EMNA 1EPIA 1A3PA 1FFMA 3N8VA 2XC4L 1U67A 1B9WA 1HT5A 1WHFA 1KIGL 3NTGA 4X8SL 1OB1C 2P28B 5JBAE 4E1GA 1IQLL 3M36L 1Z6CA 3QH0A 3K9XA 4M11A 1EPHA 3ZYGA 1LMMA 1L3YA 2K2SB 4Z0LA 2P94L 3KL6B 1IGZA 2WYGB 5JVYA 1COUA 1NFYB 2UWOB 2I9BA 4Z0KB 1L5GB 3N8YB 3ASIA 4X8TL 4ZHAB 4RUTA 3SOBB 5IKVA 2I9AA 4OTJA 1PXXA 4Y76B 3ZYIB 2W2OE 1EPGA 1LQDA 1IQGL 3SW2A 4RRWA 2W3IB 3F1SB 1XKBA 2P93L 5CISA 1IOXA 2XBYL 1LMJA 2WPLE 4Z6AL 4TGFA 4RRXA 3TZIA 1NPEB 3N8WA 3SOQA 2H9EC 1QFKL 1W7XL 3BPSE 2Y7XB 1F0RB 3KQCL 3IJEB 2B7DL 5IKQA 1NT0A 3M37L 1KSNB 3DEMA 5FDQA 2WZPP 2G00L 2NPRA 1KLJL 1CX2A 2WPJE 1DX5I 3HS5A 2W26B 1CEJA 1RFNB 2FZZL 3CA7A 2BQ6A 1WU1B 3GCXE 4Y6DB 5L30L 1PFXL 2BOXA 5I46L 1ADXA 3LC5B 2VWMK 3FFGL 1DVAL 1EQGA 2EI8B 2P3UA 4Y7BB 4BTIA 4RS0A 3HS6A 4YT6L 1HZ8A 1K36A 1HX2A 3TH3L 3P5BL 3HO4A 4D90A 1F0SB 2PR3B 3C9AC 3GISX 5E8DA 3H5CB 4XL1A 2RA0L 4O02B 3KK6A 5F19A 3NTBA 4BXSA 1EMOA 1G2LB 3CFWA 2BQWA 2P95L 2VH6B 1LPKA 4O1ZA 1XKAL 1IQHL 3LTGD 1HJ7A 2MGPA 2VWOL 2OYUP 4CUEA 1URKA 4BXWA 1X7AL 3MDLA 3R05A 1JBUL 3U7UG 4A94C 2Q1JB 2W86A 3N8YA 2MGRA 1DDXA 4JZFL 4BTTA 1CCVA 2M74A 2TGFA 2VWLL 1PRHA 2WPIE 1PGEA 2CJIB 1SZBA 1HAFA 2WFTA 5CKNA 3ZYJB 4RRYA 2FLGA 2P3FL 2YGQA 4BDWA 1FAKL 2FLRL 4D0EA 2KNIA 1WHEA 3FCSB 1IQIL 1J9CL 4JZEL 3KQBL 2W2ME 2BOHA 2Y81B 4BDXA 4LORA 2J2UB 4G1MB 3ELAL 1YUKB 2BOUA 3TGFA 2YGPA 4ZXXL 3TK6B 1ATDA 5JBBE 2BMGA 1PTHA 3LN0A 3LC3B 2P3FN 1TPGA 4CUFA 1EAIC 1FJSL 1U8CB 4Y79B 1NFUB 2UWLB 4X8UL 6COXA 1IOEL 2Y5GL 3TBDA 2WFXB 4JYVL 4FM5A 1IQJL 2AYLA 1UZKA 3N8WB 3N8ZA 2WG4B 1APOA 3KQDL 4MMYB 4C16A 1IGXA 1TOZA 1ATAA 2J38B 3HO5A 3OLTA 1NQLB 5JB8E 4ISHL 3LIWB 1K37A 3Q3KB 3KCGL 2XBWL 1TLEA 4JZDL 1APQA 3NJPC 3IITB 5JW1A 3OLUA 2W2QE 3KRKA 1AUTL 2VVUL 1G2MB 1Q4GA 1LPZA 1FAXL 3ENSA 1JV2B 2XBXL 1KLIL 1G1TA 4LMFA 3S6XA 2VWNL 2MHPA 2F9BL 2J34B 4ZH8B 1FF7A 1EGFA 5KN5C 1CCFA 4PH9A 2UWPB 3CS7L 1IVOC 1IQML 2VVCK 4Y71B 2WPKE 1FE2A 1YO8A 3V65B 2JKHL 4NA9L 4NG9L 3BT2A 2P3TA 2BQ7A 2W2NE 3Q7DA 4MMZB 4Y7AB 1FSBA 1IQKL 1ATBA 3FBYA 4M10A 1YUFA 2EI7B 3QCWA 4XBMA 1IQFL 1ZAQA 5F1AA 1HRFA 5EGMB 4YT7L 2EI6B 2P26A 4D0FA 1V3XB 2VH0B 2Y82B 1G1QA 2W3KB 2XC0L 2YGOA 4CSYA 1C5MF 2WPHE 1F7EA 3KQEL 3HPTA 1I0UA 1M1XB 3SOVA 1XFEA 2KV4A 2WPME 3QMOA 5IKRA 1UZJA 4ISIL 2XC5L 5JBCE 3EGFA 1EPJA 1YGCL 1N1IA 1MOXC 1UZPA 4BTUA 3U73A 1GK5A 2DDUA 4CUDA 1BF9A 3NT1A 2PUQL 2OYEP 2VVVL 2BOKL 5JVZA 3POYA 2J95B 2Y7ZB 1MQ5L 1N7DA 5JB9E 4XLWA 1HCGB 1DIYA 5KIRA 2Y80B 1EBVA 3MQEA 1EZQB 3BT1A 1CVUA 2BO2A 2Y38A 2FD6A 4NGAL 2KB9A 4OTYA 1O5DL 2VJ3A 1HAEA 1NFWB 3HS7A 1Z6EL 2RHPA 1EQHA 1P9JA 2K2TA 3RR3A 5CKMA 1G1RA 2RNLA 1IJQA 4AQTA 2GD4A 3LAQA 1MQ6L 2J4IB 4JYUL 2PHBB 5COXA 1HREA 1IP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JL9 A;  2Y5H L;  3GCW E;  2D1J B;  1LPG A;  2P16 L;  4YZU B;  2J94 B;  4COX A;  1NFX B;  2Y5F L;  1IQE L;  4MMX B;  1P0S L;  1CQE A;  3LTF B;  1YUG A;  3N8X A;  3LN1 A;  3CEN L;  3PGH A;  3TK5 B;  1ATE A;  4A7I A;  2KL7 A;  4X8V L;  2H9E L;  5L2Z L;  1NZI A;  4ZXY L;  5CKQ A;  1UZQ A;  1XDT R;  2W2P E;  5L2Y L;  3HO3 A;  1F7M A;  3V64 C;  2XBV L;  2FLB L;  2WYJ B;  1HT8 A;  1CVW L;  1W8B L;  2WG3 C;  2ADX A;  2BZ6 L;  1DQB A;  4ZAE B;  3F6U L;  5IKT A;  1KLO A;  4RRZ A;  1G1S A;  1IQN L;  5K0H B;  1EMN A;  1EPI A;  1A3P A;  1FFM A;  3N8V A;  2XC4 L;  1U67 A;  1B9W A;  1HT5 A;  1WHF A;  1KIG L;  3NTG A;  4X8S L;  1OB1 C;  2P28 B;  5JBA E;  4E1G A;  1IQL L;  3M36 L;  1Z6C A;  3QH0 A;  3K9X A;  4M11 A;  1EPH A;  3ZYG A;  1L3Y A;  2K2S B;  4Z0L A;  2P94 L;  3KL6 B;  1IGZ A;  2WYG B;  5JVY A;  1COU A;  1NFY B;  2UWO B;  2I9B A;  4Z0K B;  1L5G B;  3N8Y B;  3ASI A;  4X8T L;  4ZHA B;  4RUT A;  3SOB B;  5IKV A;  2I9A A;  4OTJ A;  1PXX A;  4Y76 B;  3ZYI B;  2W2O E;  1EPG A;  1LQD A;  1IQG L;  3SW2 A;  4RRW A;  2W3I B;  3F1S B;  1XKB A;  2P93 L;  5CIS A;  1IOX A;  2XBY L;  1LMJ A;  2WPL E;  4Z6A L;  4TGF A;  4RRX A;  3TZI A;  1NPE B;  3N8W A;  3SOQ A;  1QFK L;  1W7X L;  3BPS E;  2Y7X B;  1F0R B;  3KQC L;  3IJE B;  2B7D L;  5IKQ A;  1NT0 A;  3M37 L;  1KSN B;  3DEM A;  5FDQ A;  2G00 L;  2NPR A;  1KLJ L;  1CX2 A;  2WPJ E;  1DX5 I;  3HS5 A;  2W26 B;  1CEJ A;  1RFN B;  2FZZ L;  3CA7 A;  2BQ6 A;  1WU1 B;  3GCX E;  4Y6D B;  5L30 L;  1PFX L;  2BOX A;  5I46 L;  1ADX A;  3LC5 B;  2VWM K;  3FFG L;  1DVA L;  1EQG A;  2EI8 B;  2P3U A;  4Y7B B;  4BTI A;  4RS0 A;  3HS6 A;  4YT6 L;  1HZ8 A;  1K36 A;  1HX2 A;  3TH3 L;  3P5B L;  3HO4 A;  4D90 A;  1F0S B;  2PR3 B;  3C9A C;  3GIS X;  5E8D A;  3H5C B;  4XL1 A;  2RA0 L;  4O02 B;  3KK6 A;  5F19 A;  3NTB A;  4BXS A;  1EMO A;  1G2L B;  3CFW A;  2BQW A;  2P95 L;  2VH6 B;  1LPK A;  4O1Z A;  1XKA L;  1IQH L;  3LTG D;  1HJ7 A;  2MGP A;  2VWO L;  2OYU P;  4CUE A;  1URK A;  4BXW A;  1X7A L;  3MDL A;  3R05 A;  1JBU L;  3U7U G;  2Q1J B;  2W86 A;  3N8Y A;  2MGR A;  1DDX A;  4JZF L;  4BTT A;  1CCV A;  2M74 A;  2TGF A;  2VWL L;  1PRH A;  2WPI E;  1PGE A;  2CJI B;  1SZB A;  1HAF A;  2WFT A;  5CKN A;  3ZYJ B;  4RRY A;  2FLG A;  2P3F L;  4BDW A;  1FAK L;  2FLR L;  4D0E A;  1WHE A;  3FCS B;  1IQI L;  1J9C L;  4JZE L;  3KQB L;  2W2M E;  2BOH A;  2Y81 B;  4BDX A;  4LOR A;  2J2U B;  4G1M B;  3ELA L;  1YUK B;  2BOU A;  3TGF A;  2YGP A;  4ZXX L;  3TK6 B;  1ATD A;  5JBB E;  2BMG A;  1PTH A;  3LN0 A;  3LC3 B;  2P3F N;  1TPG A;  4CUF A;  1EAI C;  1FJS L;  1U8C B;  4Y79 B;  1NFU B;  2UWL B;  4X8U L;  6COX A;  1IOE L;  2Y5G L;  3TBD A;  2WFX B;  4JYV L;  4FM5 A;  1IQJ L;  2AYL A;  1UZK A;  3N8W B;  3N8Z A;  2WG4 B;  1APO A;  3KQD L;  4MMY B;  4C16 A;  1IGX A;  1TOZ A;  1ATA A;  2J38 B;  3HO5 A;  3OLT A;  1NQL B;  5JB8 E;  4ISH L;  3LIW B;  1K37 A;  3Q3K B;  3KCG L;  2XBW L;  1TLE A;  4JZD L;  1APQ A;  3NJP C;  3IIT B;  5JW1 A;  3OLU A;  2W2Q E;  3KRK A;  1AUT L;  2VVU L;  1G2M B;  1Q4G A;  1LPZ A;  1FAX L;  3ENS A;  1JV2 B;  2XBX L;  1KLI L;  1G1T A;  4LMF A;  2VWN L;  2MHP A;  2F9B L;  2J34 B;  4ZH8 B;  1FF7 A;  1EGF A;  5KN5 C;  1CCF A;  4PH9 A;  2UWP B;  3CS7 L;  1IVO C;  1IQM L;  2VVC K;  4Y71 B;  2WPK E;  1FE2 A;  1YO8 A;  3V65 B;  2JKH L;  4NA9 L;  4NG9 L;  3BT2 A;  2P3T A;  2BQ7 A;  2W2N E;  3Q7D A;  4MMZ B;  4Y7A B;  1FSB A;  1IQK L;  1ATB A;  3FBY A;  4M10 A;  1YUF A;  2EI7 B;  3QCW A;  4XBM A;  1IQF L;  1ZAQ A;  5F1A A;  1HRF A;  5EGM B;  4YT7 L;  2EI6 B;  2P26 A;  4D0F A;  1V3X B;  2VH0 B;  2Y82 B;  1G1Q A;  2W3K B;  2XC0 L;  2YGO A;  4CSY A;  1C5M F;  2WPH E;  1F7E A;  3KQE L;  3HPT A;  1I0U A;  1M1X B;  3SOV A;  1XFE A;  2KV4 A;  2WPM E;  3QMO A;  5IKR A;  1UZJ A;  4ISI L;  2XC5 L;  5JBC E;  3EGF A;  1EPJ A;  1YGC L;  1N1I A;  1MOX C;  1UZP A;  4BTU A;  3U73 A;  1GK5 A;  2DDU A;  4CUD A;  1BF9 A;  3NT1 A;  2PUQ L;  2OYE P;  2VVV L;  2BOK L;  5JVZ A;  3POY A;  2J95 B;  2Y7Z B;  1MQ5 L;  1N7D A;  5JB9 E;  4XLW A;  1HCG B;  1DIY A;  5KIR A;  2Y80 B;  1EBV A;  3MQE A;  1EZQ B;  3BT1 A;  1CVU A;  2BO2 A;  2Y38 A;  2FD6 A;  4NGA L;  2KB9 A;  4OTY A;  1O5D L;  2VJ3 A;  1HAE A;  1NFW B;  3HS7 A;  1Z6E L;  2RHP A;  1EQH A;  1P9J A;  2K2T A;  3RR3 A;  5CKM A;  1G1R A;  2RNL A;  1IJQ A;  4AQT A;  2GD4 A;  3LAQ A;  1MQ6 L;  2J4I B;  4JYU L;  2PHB B;  5COX A;  1HRE A;  1IP0 A; 
#chains in the Genus database with same CATH topology
 1JL9 A;  2Y5H L;  3GCW E;  2D1J B;  1LPG A;  2P16 L;  4YZU B;  2J94 B;  4COX A;  1NFX B;  2HOX A;  2Y5F L;  1IQE L;  4MMX B;  1P0S L;  1CQE A;  3LTF B;  1YUG A;  3N8X A;  3LN1 A;  2BT7 A;  3CEN L;  3PGH A;  3TK5 B;  1ATE A;  4A7I A;  2KL7 A;  4X8V L;  2H9E L;  5L2Z L;  1NZI A;  4ZXY L;  5CKQ A;  1UZQ A;  1XDT R;  2W2P E;  5L2Y L;  3HO3 A;  1F7M A;  3V64 C;  2XBV L;  2FLB L;  2WYJ B;  1HT8 A;  1CVW L;  1W8B L;  2WG3 C;  2ADX A;  2BZ6 L;  1DQB A;  4ZAE B;  3F6U L;  5IKT A;  1KLO A;  4RRZ A;  1G1S A;  1IQN L;  5K0H B;  1EMN A;  1EPI A;  1A3P A;  1FFM A;  3N8V A;  2XC4 L;  1U67 A;  1B9W A;  1HT5 A;  1WHF A;  1KIG L;  3NTG A;  4X8S L;  1OB1 C;  2P28 B;  5JBA E;  4E1G A;  1IQL L;  3M36 L;  1Z6C A;  3QH0 A;  3K9X A;  4M11 A;  1EPH A;  3ZYG A;  1LMM A;  1L3Y A;  2K2S B;  4GU4 A;  4Z0L A;  2HOR A;  2P94 L;  3KL6 B;  1IGZ A;  2WYG B;  5JVY A;  1COU A;  1NFY B;  2UWO B;  2I9B A;  4Z0K B;  1L5G B;  3N8Y B;  3ASI A;  4X8T L;  4ZHA B;  4RUT A;  3SOB B;  5IKV A;  2BSF A;  2I9A A;  4OTJ A;  1PXX A;  4Y76 B;  3ZYI B;  2W2O E;  1EPG A;  1LQD A;  1IQG L;  3SW2 A;  4RRW A;  2W3I B;  3F1S B;  1XKB A;  2P93 L;  5CIS A;  1IOX A;  2XBY L;  1LMJ A;  2WPL E;  4Z6A L;  4TGF A;  4RRX A;  3TZI A;  1NPE B;  2JJL A;  3N8W A;  3SOQ A;  2H9E C;  1QFK L;  1W7X L;  3BPS E;  2Y7X B;  1F0R B;  3KQC L;  3IJE B;  2B7D L;  5IKQ A;  1NT0 A;  3M37 L;  1KSN B;  3DEM A;  5FDQ A;  2WZP P;  2G00 L;  2NPR A;  1KLJ L;  1CX2 A;  2WPJ E;  1DX5 I;  3HS5 A;  2W26 B;  1CEJ A;  1RFN B;  2FZZ L;  3CA7 A;  2BQ6 A;  1WU1 B;  3GCX E;  4Y6D B;  5L30 L;  1PFX L;  2BOX A;  5I46 L;  1ADX A;  3LC5 B;  2VWM K;  1LK9 A;  3FFG L;  1DVA L;  1EQG A;  2EI8 B;  2P3U A;  4Y7B B;  4BTI A;  4RS0 A;  3HS6 A;  4YT6 L;  1HZ8 A;  1K36 A;  1HX2 A;  3TH3 L;  3P5B L;  3HO4 A;  4D90 A;  1F0S B;  2PR3 B;  3C9A C;  3GIS X;  5E8D A;  3H5C B;  4XL1 A;  2RA0 L;  4O02 B;  3KK6 A;  5F19 A;  3NTB A;  4BXS A;  1EMO A;  1G2L B;  3CFW A;  2BQW A;  2P95 L;  2VH6 B;  1LPK A;  4O1Z A;  1XKA L;  1IQH L;  3LTG D;  1HJ7 A;  2MGP A;  2VWO L;  2OYU P;  4CUE A;  1URK A;  4BXW A;  1X7A L;  3MDL A;  3R05 A;  1JBU L;  3U7U G;  4A94 C;  2Q1J B;  2W86 A;  3N8Y A;  2MGR A;  1DDX A;  4JZF L;  4BTT A;  1CCV A;  2M74 A;  2VRS A;  2TGF A;  2VWL L;  1PRH A;  2WPI E;  1PGE A;  2CJI B;  1SZB A;  1HAF A;  2WFT A;  5CKN A;  3ZYJ B;  4RRY A;  2FLG A;  2P3F L;  2YGQ A;  4BDW A;  1FAK L;  2FLR L;  4D0E A;  2KNI A;  1WHE A;  3FCS B;  1IQI L;  1J9C L;  4JZE L;  3KQB L;  2W2M E;  2BOH A;  2Y81 B;  4BDX A;  4LOR A;  2J2U B;  4G1M B;  3ELA L;  1YUK B;  2BOU A;  3TGF A;  2YGP A;  4ZXX L;  3TK6 B;  1ATD A;  5JBB E;  2BMG A;  1PTH A;  3LN0 A;  3LC3 B;  2P3F N;  1TPG A;  4CUF A;  1EAI C;  1FJS L;  1U8C B;  4Y79 B;  1NFU B;  2UWL B;  4X8U L;  6COX A;  1IOE L;  2Y5G L;  3TBD A;  2WFX B;  4JYV L;  4FM5 A;  1IQJ L;  2AYL A;  1UZK A;  3N8W B;  3N8Z A;  2WG4 B;  1APO A;  3KQD L;  4MMY B;  4C16 A;  1IGX A;  1KKE A;  1TOZ A;  1ATA A;  2J38 B;  3HO5 A;  3OLT A;  1NQL B;  5JB8 E;  4ISH L;  1V1I A;  3LIW B;  1K37 A;  3Q3K B;  3KCG L;  2XBW L;  1TLE A;  4JZD L;  1APQ A;  3NJP C;  3IIT B;  5JW1 A;  3OLU A;  2W2Q E;  3KRK A;  1AUT L;  4GU3 A;  2VVU L;  1G2M B;  1Q4G A;  1LPZ A;  1FAX L;  3ENS A;  1JV2 B;  2XBX L;  1KLI L;  1G1T A;  4LMF A;  3S6X A;  2VWN L;  2MHP A;  2F9B L;  2J34 B;  4ZH8 B;  1FF7 A;  1EGF A;  5KN5 C;  1CCF A;  4PH9 A;  2UWP B;  3CS7 L;  1IVO C;  1IQM L;  2VVC K;  4Y71 B;  2WPK E;  1FE2 A;  1YO8 A;  3V65 B;  2JKH L;  4NA9 L;  4NG9 L;  3BT2 A;  2P3T A;  2BQ7 A;  2W2N E;  3Q7D A;  4MMZ B;  4Y7A B;  1FSB A;  1IQK L;  1ATB A;  3FBY A;  4M10 A;  1YUF A;  2EI7 B;  3QCW A;  4XBM A;  1IQF L;  1ZAQ A;  5F1A A;  1HRF A;  5EGM B;  4YT7 L;  2EI6 B;  2P26 A;  4D0F A;  1V3X B;  2VH0 B;  2Y82 B;  1G1Q A;  2W3K B;  2XC0 L;  2YGO A;  4CSY A;  1C5M F;  2WPH E;  1F7E A;  3KQE L;  3HPT A;  1I0U A;  1M1X B;  3SOV A;  1XFE A;  2KV4 A;  1V1H A;  2WPM E;  3QMO A;  5IKR A;  1UZJ A;  4ISI L;  2XC5 L;  5JBC E;  3EGF A;  1EPJ A;  1YGC L;  1N1I A;  1MOX C;  1UZP A;  4BTU A;  3U73 A;  1GK5 A;  2DDU A;  4CUD A;  1BF9 A;  3NT1 A;  2PUQ L;  2OYE P;  2VVV L;  2BT8 A;  2BOK L;  5JVZ A;  3POY A;  2J95 B;  2Y7Z B;  1MQ5 L;  1N7D A;  5JB9 E;  4XLW A;  1HCG B;  1DIY A;  5KIR A;  2Y80 B;  1EBV A;  3MQE A;  1EZQ B;  3BT1 A;  1CVU A;  2BO2 A;  2Y38 A;  2FD6 A;  4NGA L;  2KB9 A;  4OTY A;  1O5D L;  2VJ3 A;  1HAE A;  1NFW B;  3HS7 A;  1Z6E L;  2RHP A;  1EQH A;  1P9J A;  2K2T A;  3RR3 A;  5CKM A;  1G1R A;  2RNL A;  1IJQ A;  4AQT A;  2GD4 A;  1QIU A;  3LAQ A;  1MQ6 L;  2J4I B;  4JYU L;  2PHB B;  5COX A;  1HRE A;  1IP0 A; 
#chains in the Genus database with same CATH homology
 1JL9 A;  2Y5H L;  3GCW E;  2D1J B;  1LPG A;  2P16 L;  4YZU B;  2J94 B;  4COX A;  1NFX B;  2Y5F L;  1IQE L;  4MMX B;  1P0S L;  1CQE A;  3LTF B;  1YUG A;  3N8X A;  3LN1 A;  3CEN L;  3PGH A;  3TK5 B;  1ATE A;  4A7I A;  2KL7 A;  4X8V L;  2H9E L;  5L2Z L;  1NZI A;  4ZXY L;  5CKQ A;  1UZQ A;  1XDT R;  2W2P E;  5L2Y L;  3HO3 A;  1F7M A;  3V64 C;  2XBV L;  2FLB L;  2WYJ B;  1HT8 A;  1CVW L;  1W8B L;  2WG3 C;  2ADX A;  2BZ6 L;  1DQB A;  4ZAE B;  3F6U L;  5IKT A;  1KLO A;  4RRZ A;  1G1S A;  1IQN L;  5K0H B;  1EMN A;  1EPI A;  1A3P A;  1FFM A;  3N8V A;  2XC4 L;  1U67 A;  1B9W A;  1HT5 A;  1WHF A;  1KIG L;  3NTG A;  4X8S L;  1OB1 C;  2P28 B;  5JBA E;  4E1G A;  1IQL L;  3M36 L;  1Z6C A;  3QH0 A;  3K9X A;  4M11 A;  1EPH A;  3ZYG A;  1LMM A;  1L3Y A;  2K2S B;  4Z0L A;  2P94 L;  3KL6 B;  1IGZ A;  2WYG B;  5JVY A;  1COU A;  1NFY B;  2UWO B;  2I9B A;  4Z0K B;  1L5G B;  3N8Y B;  3ASI A;  4X8T L;  4ZHA B;  4RUT A;  3SOB B;  5IKV A;  2I9A A;  4OTJ A;  1PXX A;  4Y76 B;  3ZYI B;  2W2O E;  1EPG A;  1LQD A;  1IQG L;  3SW2 A;  4RRW A;  2W3I B;  3F1S B;  1XKB A;  2P93 L;  5CIS A;  1IOX A;  2XBY L;  1LMJ A;  2WPL E;  4Z6A L;  4TGF A;  4RRX A;  3TZI A;  1NPE B;  3N8W A;  3SOQ A;  2H9E C;  1QFK L;  1W7X L;  3BPS E;  2Y7X B;  1F0R B;  3KQC L;  3IJE B;  2B7D L;  5IKQ A;  1NT0 A;  3M37 L;  1KSN B;  3DEM A;  5FDQ A;  2WZP P;  2G00 L;  2NPR A;  1KLJ L;  1CX2 A;  2WPJ E;  1DX5 I;  3HS5 A;  2W26 B;  1CEJ A;  1RFN B;  2FZZ L;  3CA7 A;  2BQ6 A;  1WU1 B;  3GCX E;  4Y6D B;  5L30 L;  1PFX L;  2BOX A;  5I46 L;  1ADX A;  3LC5 B;  2VWM K;  3FFG L;  1DVA L;  1EQG A;  2EI8 B;  2P3U A;  4Y7B B;  4BTI A;  4RS0 A;  3HS6 A;  4YT6 L;  1HZ8 A;  1K36 A;  1HX2 A;  3TH3 L;  3P5B L;  3HO4 A;  4D90 A;  1F0S B;  2PR3 B;  3C9A C;  3GIS X;  5E8D A;  3H5C B;  4XL1 A;  2RA0 L;  4O02 B;  3KK6 A;  5F19 A;  3NTB A;  4BXS A;  1EMO A;  1G2L B;  3CFW A;  2BQW A;  2P95 L;  2VH6 B;  1LPK A;  4O1Z A;  1XKA L;  1IQH L;  3LTG D;  1HJ7 A;  2MGP A;  2VWO L;  2OYU P;  4CUE A;  1URK A;  4BXW A;  1X7A L;  3MDL A;  3R05 A;  1JBU L;  3U7U G;  4A94 C;  2Q1J B;  2W86 A;  3N8Y A;  2MGR A;  1DDX A;  4JZF L;  4BTT A;  1CCV A;  2M74 A;  2TGF A;  2VWL L;  1PRH A;  2WPI E;  1PGE A;  2CJI B;  1SZB A;  1HAF A;  2WFT A;  5CKN A;  3ZYJ B;  4RRY A;  2FLG A;  2P3F L;  2YGQ A;  4BDW A;  1FAK L;  2FLR L;  4D0E A;  2KNI A;  1WHE A;  3FCS B;  1IQI L;  1J9C L;  4JZE L;  3KQB L;  2W2M E;  2BOH A;  2Y81 B;  4BDX A;  4LOR A;  2J2U B;  4G1M B;  3ELA L;  1YUK B;  2BOU A;  3TGF A;  2YGP A;  4ZXX L;  3TK6 B;  1ATD A;  5JBB E;  2BMG A;  1PTH A;  3LN0 A;  3LC3 B;  2P3F N;  1TPG A;  4CUF A;  1EAI C;  1FJS L;  1U8C B;  4Y79 B;  1NFU B;  2UWL B;  4X8U L;  6COX A;  1IOE L;  2Y5G L;  3TBD A;  2WFX B;  4JYV L;  4FM5 A;  1IQJ L;  2AYL A;  1UZK A;  3N8W B;  3N8Z A;  2WG4 B;  1APO A;  3KQD L;  4MMY B;  4C16 A;  1IGX A;  1TOZ A;  1ATA A;  2J38 B;  3HO5 A;  3OLT A;  1NQL B;  5JB8 E;  4ISH L;  3LIW B;  1K37 A;  3Q3K B;  3KCG L;  2XBW L;  1TLE A;  4JZD L;  1APQ A;  3NJP C;  3IIT B;  5JW1 A;  3OLU A;  2W2Q E;  3KRK A;  1AUT L;  2VVU L;  1G2M B;  1Q4G A;  1LPZ A;  1FAX L;  3ENS A;  1JV2 B;  2XBX L;  1KLI L;  1G1T A;  4LMF A;  3S6X A;  2VWN L;  2MHP A;  2F9B L;  2J34 B;  4ZH8 B;  1FF7 A;  1EGF A;  5KN5 C;  1CCF A;  4PH9 A;  2UWP B;  3CS7 L;  1IVO C;  1IQM L;  2VVC K;  4Y71 B;  2WPK E;  1FE2 A;  1YO8 A;  3V65 B;  2JKH L;  4NA9 L;  4NG9 L;  3BT2 A;  2P3T A;  2BQ7 A;  2W2N E;  3Q7D A;  4MMZ B;  4Y7A B;  1FSB A;  1IQK L;  1ATB A;  3FBY A;  4M10 A;  1YUF A;  2EI7 B;  3QCW A;  4XBM A;  1IQF L;  1ZAQ A;  5F1A A;  1HRF A;  5EGM B;  4YT7 L;  2EI6 B;  2P26 A;  4D0F A;  1V3X B;  2VH0 B;  2Y82 B;  1G1Q A;  2W3K B;  2XC0 L;  2YGO A;  4CSY A;  1C5M F;  2WPH E;  1F7E A;  3KQE L;  3HPT A;  1I0U A;  1M1X B;  3SOV A;  1XFE A;  2KV4 A;  2WPM E;  3QMO A;  5IKR A;  1UZJ A;  4ISI L;  2XC5 L;  5JBC E;  3EGF A;  1EPJ A;  1YGC L;  1N1I A;  1MOX C;  1UZP A;  4BTU A;  3U73 A;  1GK5 A;  2DDU A;  4CUD A;  1BF9 A;  3NT1 A;  2PUQ L;  2OYE P;  2VVV L;  2BOK L;  5JVZ A;  3POY A;  2J95 B;  2Y7Z B;  1MQ5 L;  1N7D A;  5JB9 E;  4XLW A;  1HCG B;  1DIY A;  5KIR A;  2Y80 B;  1EBV A;  3MQE A;  1EZQ B;  3BT1 A;  1CVU A;  2BO2 A;  2Y38 A;  2FD6 A;  4NGA L;  2KB9 A;  4OTY A;  1O5D L;  2VJ3 A;  1HAE A;  1NFW B;  3HS7 A;  1Z6E L;  2RHP A;  1EQH A;  1P9J A;  2K2T A;  3RR3 A;  5CKM A;  1G1R A;  2RNL A;  1IJQ A;  4AQT A;  2GD4 A;  3LAQ A;  1MQ6 L;  2J4I B;  4JYU L;  2PHB B;  5COX A;  1HRE A;  1IP0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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