2MHPA

Solution structure of the major factor viii binding region on von willebrand factor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
103
structure length
103
Chain Sequence
GAMGSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the major factor VIII binding region on von Willebrand factor
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords von Willebrand factor
total genus 9
structure length 103
sequence length 103
ec nomenclature
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01826 TIL Trypsin Inhibitor like cysteine rich domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2mhpA00
2YGOA 1DVAL 1M1XB 1EPGA 1PFXL 5EGMB 2XC0L 1YUFA 2Y7XB 3LAQA 3N8YA 2I9AA 1YO8A 3BPSE 3Q7DA 2W2ME 3ENSA 2RA0L 1EAIC 3SOBB 2Y7ZB 1G2LB 1IVOC 1EZQB 2VVUL 2FLGA 3N8VA 4OTYA 4RS0A 1G1TA 1PTHA 4M11A 3KQEL 4X8UL 3ZYJB 1BF9A 4JZFL 2M74A 1LQDA 2H9EL 2JKHL 1OB1C 1IOEL 2OYUP 4NGAL 1XKAL 2KV4A 1FAXL 4BDWA 3M36L 1ATEA 3RR3A 2Y81B 5E8DA 4D0EA 5CISA 3KRKA 1F7MA 3OLTA 3PGHA 2W26B 2WYJB 3R05A 4NA9L 1G1QA 2WPLE 3CA7A 1EPJA 1G1SA 3N8ZA 2D1JB 3N8WB 1TOZA 5IKRA 1ZAQA 4YT7L 1IQIL 1IJQA 4JZDL 3OLUA 3GCXE 1NPEB 1XDTR 4ZAEB 1LPGA 1CVWL 2J4IB 5F19A 1DX5I 2FLRL 4JZEL 4G1MB 1PRHA 1KSNB 2VWMK 1FE2A 1MQ6L 1DIYA 1IQNL 1WHFA 1UZQA 1EMNA 2KL7A 4ZH8B 4RRZA 3IITB 6COXA 1CVUA 1HRFA 3CS7L 1P9JA 2J95B 1SZBA 1APOA 3V65B 3Q3KB 3KQCL 3N8XA 4BTUA 1K36A 1YUGA 4YT6L 3M37L 5JB8E 2P94L 4AQTA 1COUA 1PGEA 1UZJA 1UZPA 1W8BL 4X8SL 3EGFA 4Y7AB 2Y82B 4Y79B 2XBVL 3BT2A 1EQGA 1HT5A 2WG3C 3LC3B 3F1SB 3LC5B 4ZXYL 3N8WA 1Q4GA 3H5CB 4OTJA 4LORA 5I46L 2W3IB 3KQDL 4JYUL 4ZXXL 5JW1A 2P3TA 2XBXL 4Z6AL 1HX2A 4FM5A 1HAFA 4Z0LA 3KK6A 1IQML 1F0RB 5JBAE 2EI7B 3CFWA 4TGFA 5CKNA 1NFYB 3QH0A 2K2SB 3K9XA 2RHPA 2BMGA 5CKQA 1JBUL 2WPIE 3HS7A 4M10A 4XLWA 2BOHA 2WFTA 3NT1A 4JYVL 2EI6B 4COXA 2MGPA 2UWLB 3ASIA 1EMOA 2KB9A 1K37A 1CCVA 1GK5A 1IQJL 5L2YL 5K0HB 1J9CL 2WG4B 1XKBA 3LN0A 4MMYB 1YUKB 2J38B 2CJIB 3NJPC 1V3XB 4Z0KB 1IQHL 5JBBE 1KLJL 2P26A 2BOUA 4CUEA 1QFKL 2PUQL 2WPHE 4D0FA 2W3KB 1LPZA 2WFXB 1NT0A 5COXA 1CX2A 3HPTA 2Y5FL 2BO2A 2FLBL 1HREA 3NTGA 2W2OE 1L5GB 4BTIA 2WYGB 1NFWB 3HO5A 2VWLL 2BZ6L 4CUDA 3U7UG 5FDQA 3KCGL 1FSBA 1IQLL 2W86A 4BXWA 1L3YA 2P93L 1O5DL 1A3PA 1KLOA 1URKA 4BDXA 1F7EA 2P28B 2J2UB 1ATAA 2DDUA 5F1AA 2J94B 3BT1A 1EQHA 1B9WA 3TK6B 2P3FL 3MQEA 1U67A 1JL9A 4Y71B 4XL1A 2B7DL 3ELAL 1U8CB 1W7XL 3SW2A 4O1ZA 1EPIA 2VVVL 5JVYA 1HCGB 4O02B 2MGRA 2XC5L 3TGFA 2RNLA 2WPKE 3FFGL 5JBCE 1CEJA 1FFMA 3LN1A 1ATBA 4ISHL 1NFUB 5JB9E 3KQBL 2BQ6A 2AYLA 2PR3B 3QMOA 2W2PE 3QCWA 3FBYA 3ZYGA 2UWOB 1WU1B 1CCFA 2Y38A 1KIGL 4ISIL 4RUTA 2VWOL 3ZYIB 2EI8B 2XBWL 1MOXC 4Y6DB 3TH3L 2BOXA 1LMJA 2XBYL 3POYA 4MMZB 1I0UA 1HAEA 3HS6A 2Y5HL 4RRYA 2BQWA 1HT8A 2Y80B 4RRWA 2J34B 1HZ8A 1YGCL 4BTTA 2K2TA 5IKTA 5L30L 2W2NE 1C5MF 1CQEA 3C9AC 5KIRA 2WPME 3TK5B 1XFEA 4LMFA 4Y7BB 4Y76B 1WHEA 1TPGA 1LPKA 2MHPA 4D90A 1F0SB 1IGZA 3F6UL 3LTFB 1IGXA 2NPRA 2FZZL 1NFXB 4CSYA 3CENL 3GCWE 1HJ7A 3TBDA 1NZIA 1TLEA 2PHBB 2VWNL 1P0SL 1IQFL 1PXXA 1IQGL 2UWPB 1Z6EL 3V64C 1KLIL 1APQA 2XC4L 1IP0A 2VH6B 3NTBA 1EBVA 3LTGD 1X7AL 1FJSL 1G1RA 2I9BA 3HO4A 4YZUB 3P5BL 1DQBA 2P95L 1IOXA 3KL6B 2Q1JB 5CKMA 1Z6CA 5L2ZL 3SOQA 1DDXA 1JV2B 4ZHAB 2P3UA 3LIWB 2BOKL 4NG9L 1IQKL 3N8YB 2W2QE 2GD4A 2TGFA 3HO3A 2VH0B 4E1GA 1ADXA 4X8VL 2VVCK 3U73A 4XBMA 4X8TL 2YGPA 3FCSB 1ATDA 4MMXB 2P3FN 2BQ7A 3IJEB 2F9BL 1AUTL 2ADXA 2G00L 5JVZA 1UZKA 5KN5C 1RFNB 5IKVA 4C16A 1G2MB 1EGFA 2P16L 5IKQA 3HS5A 3MDLA 1MQ5L 1FF7A 3DEMA 4RRXA 1EPHA 3GISX 2FD6A 2VJ3A 2Y5GL 3TZIA 1NQLB 4CUFA 1IQEL 4BXSA 1N1IA 4A7IA 4PH9A 1FAKL 2WPJE 1N7DA 3SOVA 2OYEP
chains in the Genus database with same CATH superfamily
2YGOA 1DVAL 1M1XB 1EPGA 1PFXL 5EGMB 2XC0L 1YUFA 2Y7XB 3LAQA 3N8YA 2I9AA 1YO8A 3BPSE 3Q7DA 2W2ME 3ENSA 2RA0L 1EAIC 3SOBB 2Y7ZB 1G2LB 1IVOC 1EZQB 1LK9A 2VVUL 2FLGA 3N8VA 4OTYA 4RS0A 1G1TA 1PTHA 4M11A 3KQEL 4X8UL 3ZYJB 1BF9A 4JZFL 2M74A 1LQDA 2BSFA 2H9EL 2JKHL 1OB1C 1IOEL 2OYUP 4NGAL 1XKAL 2KV4A 1FAXL 4BDWA 3M36L 1ATEA 3RR3A 2Y81B 5E8DA 4D0EA 5CISA 3KRKA 1F7MA 2BT8A 3OLTA 3PGHA 2W26B 2WYJB 3R05A 4NA9L 1G1QA 1V1IA 2WPLE 3CA7A 1EPJA 1G1SA 3N8ZA 2D1JB 3N8WB 1TOZA 5IKRA 1ZAQA 4YT7L 1IQIL 1IJQA 4JZDL 3OLUA 3GCXE 1NPEB 1XDTR 4ZAEB 1LPGA 1CVWL 2J4IB 5F19A 1DX5I 2FLRL 4JZEL 2BT7A 4G1MB 1PRHA 1KSNB 2VWMK 1FE2A 1MQ6L 1DIYA 1IQNL 1WHFA 1UZQA 1EMNA 2KL7A 4ZH8B 4RRZA 3IITB 6COXA 1CVUA 4GU4A 1HRFA 3CS7L 1P9JA 2J95B 1SZBA 1APOA 3V65B 3Q3KB 3KQCL 3N8XA 4BTUA 1LMMA 1K36A 1YUGA 4YT6L 3M37L 5JB8E 2P94L 4AQTA 1COUA 1PGEA 1UZJA 1UZPA 1W8BL 4X8SL 3EGFA 4Y7AB 2Y82B 4Y79B 2XBVL 3BT2A 1EQGA 1HT5A 2WG3C 3LC3B 3F1SB 3LC5B 4ZXYL 3N8WA 1Q4GA 3H5CB 4OTJA 4LORA 5I46L 2W3IB 1KKEA 3KQDL 4JYUL 4ZXXL 5JW1A 2P3TA 2XBXL 4Z6AL 1HX2A 4FM5A 1QIUA 1HAFA 4Z0LA 3KK6A 1IQML 1F0RB 5JBAE 2EI7B 3CFWA 4TGFA 5CKNA 1NFYB 3QH0A 2K2SB 3K9XA 2RHPA 2BMGA 5CKQA 1JBUL 2WPIE 3HS7A 4M10A 4A94C 4XLWA 2BOHA 2WFTA 3NT1A 4JYVL 2EI6B 4COXA 2MGPA 2UWLB 3ASIA 1EMOA 2KB9A 1K37A 1CCVA 1GK5A 1IQJL 5L2YL 5K0HB 1J9CL 2WG4B 1XKBA 3LN0A 4MMYB 1YUKB 2J38B 2CJIB 3NJPC 1V3XB 4Z0KB 1IQHL 5JBBE 1KLJL 2P26A 2BOUA 4CUEA 1QFKL 2PUQL 2WPHE 4D0FA 2W3KB 1LPZA 2WFXB 1NT0A 5COXA 1CX2A 3HPTA 2Y5FL 2BO2A 2FLBL 1HREA 3NTGA 2W2OE 1L5GB 4BTIA 2WYGB 1NFWB 3HO5A 2VWLL 2BZ6L 4CUDA 3U7UG 5FDQA 3KCGL 1FSBA 1IQLL 2W86A 4BXWA 1L3YA 2P93L 1O5DL 1A3PA 1KLOA 1URKA 4BDXA 1F7EA 2P28B 2J2UB 1ATAA 2DDUA 2VRSA 2J94B 5F1AA 3BT1A 1EQHA 1B9WA 3TK6B 2P3FL 3MQEA 1U67A 1JL9A 4Y71B 4XL1A 2B7DL 3ELAL 1U8CB 1W7XL 3SW2A 4O1ZA 1EPIA 2VVVL 5JVYA 1HCGB 4O02B 2MGRA 2XC5L 3TGFA 2RNLA 2WPKE 3FFGL 5JBCE 1CEJA 1FFMA 3LN1A 2JJLA 1ATBA 4ISHL 1NFUB 5JB9E 3KQBL 2BQ6A 2AYLA 2PR3B 3QMOA 2W2PE 3QCWA 3FBYA 3ZYGA 2UWOB 1WU1B 1CCFA 4GU3A 2Y38A 1KIGL 2YGQA 4ISIL 4RUTA 2VWOL 3ZYIB 2EI8B 2XBWL 1MOXC 4Y6DB 3TH3L 2BOXA 1LMJA 2XBYL 3POYA 2HORA 4MMZB 1I0UA 1HAEA 3HS6A 2Y5HL 4RRYA 2BQWA 1HT8A 2Y80B 4RRWA 2J34B 1HZ8A 1YGCL 4BTTA 3S6XA 2K2TA 5IKTA 5L30L 2W2NE 1C5MF 1CQEA 3C9AC 5KIRA 2WPME 3TK5B 1XFEA 4LMFA 4Y7BB 4Y76B 1WHEA 1TPGA 1LPKA 2MHPA 4D90A 1F0SB 1IGZA 3F6UL 3LTFB 1IGXA 2NPRA 2FZZL 1NFXB 4CSYA 3CENL 3GCWE 1HJ7A 3TBDA 1NZIA 1TLEA 2PHBB 2VWNL 1V1HA 2HOXA 1P0SL 1IQFL 1PXXA 1IQGL 2UWPB 1Z6EL 3V64C 1KLIL 1APQA 2XC4L 1IP0A 2VH6B 3NTBA 1EBVA 3LTGD 1X7AL 1FJSL 1G1RA 2I9BA 3HO4A 4YZUB 3P5BL 1DQBA 2P95L 1IOXA 3KL6B 2Q1JB 5CKMA 1Z6CA 2KNIA 5L2ZL 3SOQA 1DDXA 1JV2B 4ZHAB 2P3UA 3LIWB 2BOKL 4NG9L 1IQKL 3N8YB 2W2QE 2GD4A 2TGFA 3HO3A 2VH0B 4E1GA 1ADXA 4X8VL 2VVCK 3U73A 4XBMA 4X8TL 2YGPA 3FCSB 1ATDA 4MMXB 2P3FN 2BQ7A 3IJEB 2F9BL 1AUTL 2ADXA 2G00L 5JVZA 1UZKA 5KN5C 1RFNB 2H9EC 5IKVA 4C16A 2WZPP 1G2MB 1EGFA 2P16L 5IKQA 3HS5A 3MDLA 1MQ5L 1FF7A 3DEMA 4RRXA 1EPHA 3GISX 2FD6A 2VJ3A 2Y5GL 3TZIA 1NQLB 4CUFA 1IQEL 4BXSA 1N1IA 4A7IA 4PH9A 1FAKL 2WPJE 1N7DA 3SOVA 2OYEP
chains in the Genus database with same CATH topology
2YGOA 1DVAL 1M1XB 1EPGA 1PFXL 5EGMB 2XC0L 1YUFA 2Y7XB 3LAQA 3N8YA 2I9AA 1YO8A 3BPSE 3Q7DA 2W2ME 3ENSA 2RA0L 1EAIC 3SOBB 2Y7ZB 1G2LB 1IVOC 1EZQB 2VVUL 2FLGA 3N8VA 4OTYA 4RS0A 1G1TA 1PTHA 4M11A 3KQEL 4X8UL 3ZYJB 1BF9A 4JZFL 2M74A 1LQDA 2H9EL 2JKHL 1OB1C 1IOEL 2OYUP 4NGAL 1XKAL 2KV4A 1FAXL 4BDWA 3M36L 1ATEA 3RR3A 2Y81B 5E8DA 4D0EA 5CISA 3KRKA 1F7MA 3OLTA 3PGHA 2W26B 2WYJB 3R05A 4NA9L 1G1QA 2WPLE 3CA7A 1EPJA 1G1SA 3N8ZA 2D1JB 3N8WB 1TOZA 5IKRA 1ZAQA 4YT7L 1IQIL 1IJQA 4JZDL 3OLUA 3GCXE 1NPEB 1XDTR 4ZAEB 1LPGA 1CVWL 2J4IB 5F19A 1DX5I 2FLRL 4JZEL 4G1MB 1PRHA 1KSNB 2VWMK 1FE2A 1MQ6L 1DIYA 1IQNL 1WHFA 1UZQA 1EMNA 2KL7A 4ZH8B 4RRZA 3IITB 6COXA 1CVUA 1HRFA 3CS7L 1P9JA 2J95B 1SZBA 1APOA 3V65B 3Q3KB 3KQCL 3N8XA 4BTUA 1LMMA 1K36A 1YUGA 4YT6L 3M37L 5JB8E 2P94L 4AQTA 1COUA 1PGEA 1UZJA 1UZPA 1W8BL 4X8SL 3EGFA 4Y7AB 2Y82B 4Y79B 2XBVL 3BT2A 1EQGA 1HT5A 2WG3C 3LC3B 3F1SB 3LC5B 4ZXYL 3N8WA 1Q4GA 3H5CB 4OTJA 4LORA 5I46L 2W3IB 3KQDL 4JYUL 4ZXXL 5JW1A 2P3TA 2XBXL 4Z6AL 1HX2A 4FM5A 1HAFA 4Z0LA 3KK6A 1IQML 1F0RB 5JBAE 2EI7B 3CFWA 4TGFA 5CKNA 1NFYB 3QH0A 2K2SB 3K9XA 2RHPA 2BMGA 5CKQA 1JBUL 2WPIE 3HS7A 4M10A 4A94C 4XLWA 2BOHA 2WFTA 3NT1A 4JYVL 2EI6B 4COXA 2MGPA 2UWLB 3ASIA 1EMOA 2KB9A 1K37A 1CCVA 1GK5A 1IQJL 5L2YL 5K0HB 1J9CL 2WG4B 1XKBA 3LN0A 4MMYB 1YUKB 2J38B 2CJIB 3NJPC 1V3XB 4Z0KB 1IQHL 5JBBE 1KLJL 2P26A 2BOUA 4CUEA 1QFKL 2PUQL 2WPHE 4D0FA 2W3KB 1LPZA 2WFXB 1NT0A 5COXA 1CX2A 3HPTA 2Y5FL 2BO2A 2FLBL 1HREA 3NTGA 2W2OE 1L5GB 4BTIA 2WYGB 1NFWB 3HO5A 2VWLL 2BZ6L 4CUDA 3U7UG 5FDQA 3KCGL 1FSBA 1IQLL 2W86A 4BXWA 1L3YA 2P93L 1O5DL 1A3PA 1KLOA 1URKA 4BDXA 1F7EA 2P28B 2J2UB 1ATAA 2DDUA 5F1AA 2J94B 3BT1A 1EQHA 1B9WA 3TK6B 2P3FL 3MQEA 1U67A 1JL9A 4Y71B 4XL1A 2B7DL 3ELAL 1U8CB 1W7XL 3SW2A 4O1ZA 1EPIA 2VVVL 5JVYA 1HCGB 4O02B 2MGRA 2XC5L 3TGFA 2RNLA 2WPKE 3FFGL 5JBCE 1CEJA 1FFMA 3LN1A 1ATBA 4ISHL 1NFUB 5JB9E 3KQBL 2BQ6A 2AYLA 2PR3B 3QMOA 2W2PE 3QCWA 3FBYA 3ZYGA 2UWOB 1WU1B 1CCFA 2Y38A 1KIGL 2YGQA 4ISIL 4RUTA 2VWOL 3ZYIB 2EI8B 2XBWL 1MOXC 4Y6DB 3TH3L 2BOXA 1LMJA 2XBYL 3POYA 4MMZB 1I0UA 1HAEA 3HS6A 2Y5HL 4RRYA 2BQWA 1HT8A 2Y80B 4RRWA 2J34B 1HZ8A 1YGCL 4BTTA 3S6XA 2K2TA 5IKTA 5L30L 2W2NE 1C5MF 1CQEA 3C9AC 5KIRA 2WPME 3TK5B 1XFEA 4LMFA 4Y7BB 4Y76B 1WHEA 1TPGA 1LPKA 2MHPA 4D90A 1F0SB 1IGZA 3F6UL 3LTFB 1IGXA 2NPRA 2FZZL 1NFXB 4CSYA 3CENL 3GCWE 1HJ7A 3TBDA 1NZIA 1TLEA 2PHBB 2VWNL 1P0SL 1IQFL 1PXXA 1IQGL 2UWPB 1Z6EL 3V64C 1KLIL 1APQA 2XC4L 1IP0A 2VH6B 3NTBA 1EBVA 3LTGD 1X7AL 1FJSL 1G1RA 2I9BA 3HO4A 4YZUB 3P5BL 1DQBA 2P95L 1IOXA 3KL6B 2Q1JB 5CKMA 1Z6CA 2KNIA 5L2ZL 3SOQA 1DDXA 1JV2B 4ZHAB 2P3UA 3LIWB 2BOKL 4NG9L 1IQKL 3N8YB 2W2QE 2GD4A 2TGFA 3HO3A 2VH0B 4E1GA 1ADXA 4X8VL 2VVCK 3U73A 4XBMA 4X8TL 2YGPA 3FCSB 1ATDA 4MMXB 2P3FN 2BQ7A 3IJEB 2F9BL 1AUTL 2ADXA 2G00L 5JVZA 1UZKA 5KN5C 1RFNB 2H9EC 5IKVA 4C16A 2WZPP 1G2MB 1EGFA 2P16L 5IKQA 3HS5A 3MDLA 1MQ5L 1FF7A 3DEMA 4RRXA 1EPHA 3GISX 2FD6A 2VJ3A 2Y5GL 3TZIA 1NQLB 4CUFA 1IQEL 4BXSA 1N1IA 4A7IA 4PH9A 1FAKL 2WPJE 1N7DA 3SOVA 2OYEP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YGO A;  1DVA L;  1M1X B;  1EPG A;  1PFX L;  5EGM B;  2XC0 L;  1YUF A;  2Y7X B;  3LAQ A;  3N8Y A;  2I9A A;  1YO8 A;  3BPS E;  3Q7D A;  2W2M E;  3ENS A;  2RA0 L;  1EAI C;  3SOB B;  2Y7Z B;  1G2L B;  1IVO C;  1EZQ B;  2VVU L;  2FLG A;  3N8V A;  4OTY A;  4RS0 A;  1G1T A;  1PTH A;  4M11 A;  3KQE L;  4X8U L;  3ZYJ B;  1BF9 A;  4JZF L;  2M74 A;  1LQD A;  2H9E L;  2JKH L;  1OB1 C;  1IOE L;  2OYU P;  4NGA L;  1XKA L;  2KV4 A;  1FAX L;  4BDW A;  3M36 L;  1ATE A;  3RR3 A;  2Y81 B;  5E8D A;  4D0E A;  5CIS A;  3KRK A;  1F7M A;  3OLT A;  3PGH A;  2W26 B;  2WYJ B;  3R05 A;  4NA9 L;  1G1Q A;  2WPL E;  3CA7 A;  1EPJ A;  1G1S A;  3N8Z A;  2D1J B;  3N8W B;  1TOZ A;  5IKR A;  1ZAQ A;  4YT7 L;  1IQI L;  1IJQ A;  4JZD L;  3OLU A;  3GCX E;  1NPE B;  1XDT R;  4ZAE B;  1LPG A;  1CVW L;  2J4I B;  5F19 A;  1DX5 I;  2FLR L;  4JZE L;  4G1M B;  1PRH A;  1KSN B;  2VWM K;  1FE2 A;  1MQ6 L;  1DIY A;  1IQN L;  1WHF A;  1UZQ A;  1EMN A;  2KL7 A;  4ZH8 B;  4RRZ A;  3IIT B;  6COX A;  1CVU A;  1HRF A;  3CS7 L;  1P9J A;  2J95 B;  1SZB A;  1APO A;  3V65 B;  3Q3K B;  3KQC L;  3N8X A;  4BTU A;  1K36 A;  1YUG A;  4YT6 L;  3M37 L;  5JB8 E;  2P94 L;  4AQT A;  1COU A;  1PGE A;  1UZJ A;  1UZP A;  1W8B L;  4X8S L;  3EGF A;  4Y7A B;  2Y82 B;  4Y79 B;  2XBV L;  3BT2 A;  1EQG A;  1HT5 A;  2WG3 C;  3LC3 B;  3F1S B;  3LC5 B;  4ZXY L;  3N8W A;  1Q4G A;  3H5C B;  4OTJ A;  4LOR A;  5I46 L;  2W3I B;  3KQD L;  4JYU L;  4ZXX L;  5JW1 A;  2P3T A;  2XBX L;  4Z6A L;  1HX2 A;  4FM5 A;  1HAF A;  4Z0L A;  3KK6 A;  1IQM L;  1F0R B;  5JBA E;  2EI7 B;  3CFW A;  4TGF A;  5CKN A;  1NFY B;  3QH0 A;  2K2S B;  3K9X A;  2RHP A;  2BMG A;  5CKQ A;  1JBU L;  2WPI E;  3HS7 A;  4M10 A;  4XLW A;  2BOH A;  2WFT A;  3NT1 A;  4JYV L;  2EI6 B;  4COX A;  2MGP A;  2UWL B;  3ASI A;  1EMO A;  2KB9 A;  1K37 A;  1CCV A;  1GK5 A;  1IQJ L;  5L2Y L;  5K0H B;  1J9C L;  2WG4 B;  1XKB A;  3LN0 A;  4MMY B;  1YUK B;  2J38 B;  2CJI B;  3NJP C;  1V3X B;  4Z0K B;  1IQH L;  5JBB E;  1KLJ L;  2P26 A;  2BOU A;  4CUE A;  1QFK L;  2PUQ L;  2WPH E;  4D0F A;  2W3K B;  1LPZ A;  2WFX B;  1NT0 A;  5COX A;  1CX2 A;  3HPT A;  2Y5F L;  2BO2 A;  2FLB L;  1HRE A;  3NTG A;  2W2O E;  1L5G B;  4BTI A;  2WYG B;  1NFW B;  3HO5 A;  2VWL L;  2BZ6 L;  4CUD A;  3U7U G;  5FDQ A;  3KCG L;  1FSB A;  1IQL L;  2W86 A;  4BXW A;  1L3Y A;  2P93 L;  1O5D L;  1A3P A;  1KLO A;  1URK A;  4BDX A;  1F7E A;  2P28 B;  2J2U B;  1ATA A;  2DDU A;  5F1A A;  2J94 B;  3BT1 A;  1EQH A;  1B9W A;  3TK6 B;  2P3F L;  3MQE A;  1U67 A;  1JL9 A;  4Y71 B;  4XL1 A;  2B7D L;  3ELA L;  1U8C B;  1W7X L;  3SW2 A;  4O1Z A;  1EPI A;  2VVV L;  5JVY A;  1HCG B;  4O02 B;  2MGR A;  2XC5 L;  3TGF A;  2RNL A;  2WPK E;  3FFG L;  5JBC E;  1CEJ A;  1FFM A;  3LN1 A;  1ATB A;  4ISH L;  1NFU B;  5JB9 E;  3KQB L;  2BQ6 A;  2AYL A;  2PR3 B;  3QMO A;  2W2P E;  3QCW A;  3FBY A;  3ZYG A;  2UWO B;  1WU1 B;  1CCF A;  2Y38 A;  1KIG L;  4ISI L;  4RUT A;  2VWO L;  3ZYI B;  2EI8 B;  2XBW L;  1MOX C;  4Y6D B;  3TH3 L;  2BOX A;  1LMJ A;  2XBY L;  3POY A;  4MMZ B;  1I0U A;  1HAE A;  3HS6 A;  2Y5H L;  4RRY A;  2BQW A;  1HT8 A;  2Y80 B;  4RRW A;  2J34 B;  1HZ8 A;  1YGC L;  4BTT A;  2K2T A;  5IKT A;  5L30 L;  2W2N E;  1C5M F;  1CQE A;  3C9A C;  5KIR A;  2WPM E;  3TK5 B;  1XFE A;  4LMF A;  4Y7B B;  4Y76 B;  1WHE A;  1TPG A;  1LPK A;  2MHP A;  4D90 A;  1F0S B;  1IGZ A;  3F6U L;  3LTF B;  1IGX A;  2NPR A;  2FZZ L;  1NFX B;  4CSY A;  3CEN L;  3GCW E;  1HJ7 A;  3TBD A;  1NZI A;  1TLE A;  2PHB B;  2VWN L;  1P0S L;  1IQF L;  1PXX A;  1IQG L;  2UWP B;  1Z6E L;  3V64 C;  1KLI L;  1APQ A;  2XC4 L;  1IP0 A;  2VH6 B;  3NTB A;  1EBV A;  3LTG D;  1X7A L;  1FJS L;  1G1R A;  2I9B A;  3HO4 A;  4YZU B;  3P5B L;  1DQB A;  2P95 L;  1IOX A;  3KL6 B;  2Q1J B;  5CKM A;  1Z6C A;  5L2Z L;  3SOQ A;  1DDX A;  1JV2 B;  4ZHA B;  2P3U A;  3LIW B;  2BOK L;  4NG9 L;  1IQK L;  3N8Y B;  2W2Q E;  2GD4 A;  2TGF A;  3HO3 A;  2VH0 B;  4E1G A;  1ADX A;  4X8V L;  2VVC K;  3U73 A;  4XBM A;  4X8T L;  2YGP A;  3FCS B;  1ATD A;  4MMX B;  2P3F N;  2BQ7 A;  3IJE B;  2F9B L;  1AUT L;  2ADX A;  2G00 L;  5JVZ A;  1UZK A;  5KN5 C;  1RFN B;  5IKV A;  4C16 A;  1G2M B;  1EGF A;  2P16 L;  5IKQ A;  3HS5 A;  3MDL A;  1MQ5 L;  1FF7 A;  3DEM A;  4RRX A;  1EPH A;  3GIS X;  2FD6 A;  2VJ3 A;  2Y5G L;  3TZI A;  1NQL B;  4CUF A;  1IQE L;  4BXS A;  1N1I A;  4A7I A;  4PH9 A;  1FAK L;  2WPJ E;  1N7D A;  3SOV A;  2OYE P; 
#chains in the Genus database with same CATH topology
 2YGO A;  1DVA L;  1M1X B;  1EPG A;  1PFX L;  5EGM B;  2XC0 L;  1YUF A;  2Y7X B;  3LAQ A;  3N8Y A;  2I9A A;  1YO8 A;  3BPS E;  3Q7D A;  2W2M E;  3ENS A;  2RA0 L;  1EAI C;  3SOB B;  2Y7Z B;  1G2L B;  1IVO C;  1EZQ B;  1LK9 A;  2VVU L;  2FLG A;  3N8V A;  4OTY A;  4RS0 A;  1G1T A;  1PTH A;  4M11 A;  3KQE L;  4X8U L;  3ZYJ B;  1BF9 A;  4JZF L;  2M74 A;  1LQD A;  2BSF A;  2H9E L;  2JKH L;  1OB1 C;  1IOE L;  2OYU P;  4NGA L;  1XKA L;  2KV4 A;  1FAX L;  4BDW A;  3M36 L;  1ATE A;  3RR3 A;  2Y81 B;  5E8D A;  4D0E A;  5CIS A;  3KRK A;  1F7M A;  2BT8 A;  3OLT A;  3PGH A;  2W26 B;  2WYJ B;  3R05 A;  4NA9 L;  1G1Q A;  1V1I A;  2WPL E;  3CA7 A;  1EPJ A;  1G1S A;  3N8Z A;  2D1J B;  3N8W B;  1TOZ A;  5IKR A;  1ZAQ A;  4YT7 L;  1IQI L;  1IJQ A;  4JZD L;  3OLU A;  3GCX E;  1NPE B;  1XDT R;  4ZAE B;  1LPG A;  1CVW L;  2J4I B;  5F19 A;  1DX5 I;  2FLR L;  4JZE L;  2BT7 A;  4G1M B;  1PRH A;  1KSN B;  2VWM K;  1FE2 A;  1MQ6 L;  1DIY A;  1IQN L;  1WHF A;  1UZQ A;  1EMN A;  2KL7 A;  4ZH8 B;  4RRZ A;  3IIT B;  6COX A;  1CVU A;  4GU4 A;  1HRF A;  3CS7 L;  1P9J A;  2J95 B;  1SZB A;  1APO A;  3V65 B;  3Q3K B;  3KQC L;  3N8X A;  4BTU A;  1LMM A;  1K36 A;  1YUG A;  4YT6 L;  3M37 L;  5JB8 E;  2P94 L;  4AQT A;  1COU A;  1PGE A;  1UZJ A;  1UZP A;  1W8B L;  4X8S L;  3EGF A;  4Y7A B;  2Y82 B;  4Y79 B;  2XBV L;  3BT2 A;  1EQG A;  1HT5 A;  2WG3 C;  3LC3 B;  3F1S B;  3LC5 B;  4ZXY L;  3N8W A;  1Q4G A;  3H5C B;  4OTJ A;  4LOR A;  5I46 L;  2W3I B;  1KKE A;  3KQD L;  4JYU L;  4ZXX L;  5JW1 A;  2P3T A;  2XBX L;  4Z6A L;  1HX2 A;  4FM5 A;  1QIU A;  1HAF A;  4Z0L A;  3KK6 A;  1IQM L;  1F0R B;  5JBA E;  2EI7 B;  3CFW A;  4TGF A;  5CKN A;  1NFY B;  3QH0 A;  2K2S B;  3K9X A;  2RHP A;  2BMG A;  5CKQ A;  1JBU L;  2WPI E;  3HS7 A;  4M10 A;  4A94 C;  4XLW A;  2BOH A;  2WFT A;  3NT1 A;  4JYV L;  2EI6 B;  4COX A;  2MGP A;  2UWL B;  3ASI A;  1EMO A;  2KB9 A;  1K37 A;  1CCV A;  1GK5 A;  1IQJ L;  5L2Y L;  5K0H B;  1J9C L;  2WG4 B;  1XKB A;  3LN0 A;  4MMY B;  1YUK B;  2J38 B;  2CJI B;  3NJP C;  1V3X B;  4Z0K B;  1IQH L;  5JBB E;  1KLJ L;  2P26 A;  2BOU A;  4CUE A;  1QFK L;  2PUQ L;  2WPH E;  4D0F A;  2W3K B;  1LPZ A;  2WFX B;  1NT0 A;  5COX A;  1CX2 A;  3HPT A;  2Y5F L;  2BO2 A;  2FLB L;  1HRE A;  3NTG A;  2W2O E;  1L5G B;  4BTI A;  2WYG B;  1NFW B;  3HO5 A;  2VWL L;  2BZ6 L;  4CUD A;  3U7U G;  5FDQ A;  3KCG L;  1FSB A;  1IQL L;  2W86 A;  4BXW A;  1L3Y A;  2P93 L;  1O5D L;  1A3P A;  1KLO A;  1URK A;  4BDX A;  1F7E A;  2P28 B;  2J2U B;  1ATA A;  2DDU A;  2VRS A;  2J94 B;  5F1A A;  3BT1 A;  1EQH A;  1B9W A;  3TK6 B;  2P3F L;  3MQE A;  1U67 A;  1JL9 A;  4Y71 B;  4XL1 A;  2B7D L;  3ELA L;  1U8C B;  1W7X L;  3SW2 A;  4O1Z A;  1EPI A;  2VVV L;  5JVY A;  1HCG B;  4O02 B;  2MGR A;  2XC5 L;  3TGF A;  2RNL A;  2WPK E;  3FFG L;  5JBC E;  1CEJ A;  1FFM A;  3LN1 A;  2JJL A;  1ATB A;  4ISH L;  1NFU B;  5JB9 E;  3KQB L;  2BQ6 A;  2AYL A;  2PR3 B;  3QMO A;  2W2P E;  3QCW A;  3FBY A;  3ZYG A;  2UWO B;  1WU1 B;  1CCF A;  4GU3 A;  2Y38 A;  1KIG L;  2YGQ A;  4ISI L;  4RUT A;  2VWO L;  3ZYI B;  2EI8 B;  2XBW L;  1MOX C;  4Y6D B;  3TH3 L;  2BOX A;  1LMJ A;  2XBY L;  3POY A;  2HOR A;  4MMZ B;  1I0U A;  1HAE A;  3HS6 A;  2Y5H L;  4RRY A;  2BQW A;  1HT8 A;  2Y80 B;  4RRW A;  2J34 B;  1HZ8 A;  1YGC L;  4BTT A;  3S6X A;  2K2T A;  5IKT A;  5L30 L;  2W2N E;  1C5M F;  1CQE A;  3C9A C;  5KIR A;  2WPM E;  3TK5 B;  1XFE A;  4LMF A;  4Y7B B;  4Y76 B;  1WHE A;  1TPG A;  1LPK A;  2MHP A;  4D90 A;  1F0S B;  1IGZ A;  3F6U L;  3LTF B;  1IGX A;  2NPR A;  2FZZ L;  1NFX B;  4CSY A;  3CEN L;  3GCW E;  1HJ7 A;  3TBD A;  1NZI A;  1TLE A;  2PHB B;  2VWN L;  1V1H A;  2HOX A;  1P0S L;  1IQF L;  1PXX A;  1IQG L;  2UWP B;  1Z6E L;  3V64 C;  1KLI L;  1APQ A;  2XC4 L;  1IP0 A;  2VH6 B;  3NTB A;  1EBV A;  3LTG D;  1X7A L;  1FJS L;  1G1R A;  2I9B A;  3HO4 A;  4YZU B;  3P5B L;  1DQB A;  2P95 L;  1IOX A;  3KL6 B;  2Q1J B;  5CKM A;  1Z6C A;  2KNI A;  5L2Z L;  3SOQ A;  1DDX A;  1JV2 B;  4ZHA B;  2P3U A;  3LIW B;  2BOK L;  4NG9 L;  1IQK L;  3N8Y B;  2W2Q E;  2GD4 A;  2TGF A;  3HO3 A;  2VH0 B;  4E1G A;  1ADX A;  4X8V L;  2VVC K;  3U73 A;  4XBM A;  4X8T L;  2YGP A;  3FCS B;  1ATD A;  4MMX B;  2P3F N;  2BQ7 A;  3IJE B;  2F9B L;  1AUT L;  2ADX A;  2G00 L;  5JVZ A;  1UZK A;  5KN5 C;  1RFN B;  2H9E C;  5IKV A;  4C16 A;  2WZP P;  1G2M B;  1EGF A;  2P16 L;  5IKQ A;  3HS5 A;  3MDL A;  1MQ5 L;  1FF7 A;  3DEM A;  4RRX A;  1EPH A;  3GIS X;  2FD6 A;  2VJ3 A;  2Y5G L;  3TZI A;  1NQL B;  4CUF A;  1IQE L;  4BXS A;  1N1I A;  4A7I A;  4PH9 A;  1FAK L;  2WPJ E;  1N7D A;  3SOV A;  2OYE P; 
#chains in the Genus database with same CATH homology
 2YGO A;  1DVA L;  1M1X B;  1EPG A;  1PFX L;  5EGM B;  2XC0 L;  1YUF A;  2Y7X B;  3LAQ A;  3N8Y A;  2I9A A;  1YO8 A;  3BPS E;  3Q7D A;  2W2M E;  3ENS A;  2RA0 L;  1EAI C;  3SOB B;  2Y7Z B;  1G2L B;  1IVO C;  1EZQ B;  2VVU L;  2FLG A;  3N8V A;  4OTY A;  4RS0 A;  1G1T A;  1PTH A;  4M11 A;  3KQE L;  4X8U L;  3ZYJ B;  1BF9 A;  4JZF L;  2M74 A;  1LQD A;  2H9E L;  2JKH L;  1OB1 C;  1IOE L;  2OYU P;  4NGA L;  1XKA L;  2KV4 A;  1FAX L;  4BDW A;  3M36 L;  1ATE A;  3RR3 A;  2Y81 B;  5E8D A;  4D0E A;  5CIS A;  3KRK A;  1F7M A;  3OLT A;  3PGH A;  2W26 B;  2WYJ B;  3R05 A;  4NA9 L;  1G1Q A;  2WPL E;  3CA7 A;  1EPJ A;  1G1S A;  3N8Z A;  2D1J B;  3N8W B;  1TOZ A;  5IKR A;  1ZAQ A;  4YT7 L;  1IQI L;  1IJQ A;  4JZD L;  3OLU A;  3GCX E;  1NPE B;  1XDT R;  4ZAE B;  1LPG A;  1CVW L;  2J4I B;  5F19 A;  1DX5 I;  2FLR L;  4JZE L;  4G1M B;  1PRH A;  1KSN B;  2VWM K;  1FE2 A;  1MQ6 L;  1DIY A;  1IQN L;  1WHF A;  1UZQ A;  1EMN A;  2KL7 A;  4ZH8 B;  4RRZ A;  3IIT B;  6COX A;  1CVU A;  1HRF A;  3CS7 L;  1P9J A;  2J95 B;  1SZB A;  1APO A;  3V65 B;  3Q3K B;  3KQC L;  3N8X A;  4BTU A;  1LMM A;  1K36 A;  1YUG A;  4YT6 L;  3M37 L;  5JB8 E;  2P94 L;  4AQT A;  1COU A;  1PGE A;  1UZJ A;  1UZP A;  1W8B L;  4X8S L;  3EGF A;  4Y7A B;  2Y82 B;  4Y79 B;  2XBV L;  3BT2 A;  1EQG A;  1HT5 A;  2WG3 C;  3LC3 B;  3F1S B;  3LC5 B;  4ZXY L;  3N8W A;  1Q4G A;  3H5C B;  4OTJ A;  4LOR A;  5I46 L;  2W3I B;  3KQD L;  4JYU L;  4ZXX L;  5JW1 A;  2P3T A;  2XBX L;  4Z6A L;  1HX2 A;  4FM5 A;  1HAF A;  4Z0L A;  3KK6 A;  1IQM L;  1F0R B;  5JBA E;  2EI7 B;  3CFW A;  4TGF A;  5CKN A;  1NFY B;  3QH0 A;  2K2S B;  3K9X A;  2RHP A;  2BMG A;  5CKQ A;  1JBU L;  2WPI E;  3HS7 A;  4M10 A;  4A94 C;  4XLW A;  2BOH A;  2WFT A;  3NT1 A;  4JYV L;  2EI6 B;  4COX A;  2MGP A;  2UWL B;  3ASI A;  1EMO A;  2KB9 A;  1K37 A;  1CCV A;  1GK5 A;  1IQJ L;  5L2Y L;  5K0H B;  1J9C L;  2WG4 B;  1XKB A;  3LN0 A;  4MMY B;  1YUK B;  2J38 B;  2CJI B;  3NJP C;  1V3X B;  4Z0K B;  1IQH L;  5JBB E;  1KLJ L;  2P26 A;  2BOU A;  4CUE A;  1QFK L;  2PUQ L;  2WPH E;  4D0F A;  2W3K B;  1LPZ A;  2WFX B;  1NT0 A;  5COX A;  1CX2 A;  3HPT A;  2Y5F L;  2BO2 A;  2FLB L;  1HRE A;  3NTG A;  2W2O E;  1L5G B;  4BTI A;  2WYG B;  1NFW B;  3HO5 A;  2VWL L;  2BZ6 L;  4CUD A;  3U7U G;  5FDQ A;  3KCG L;  1FSB A;  1IQL L;  2W86 A;  4BXW A;  1L3Y A;  2P93 L;  1O5D L;  1A3P A;  1KLO A;  1URK A;  4BDX A;  1F7E A;  2P28 B;  2J2U B;  1ATA A;  2DDU A;  5F1A A;  2J94 B;  3BT1 A;  1EQH A;  1B9W A;  3TK6 B;  2P3F L;  3MQE A;  1U67 A;  1JL9 A;  4Y71 B;  4XL1 A;  2B7D L;  3ELA L;  1U8C B;  1W7X L;  3SW2 A;  4O1Z A;  1EPI A;  2VVV L;  5JVY A;  1HCG B;  4O02 B;  2MGR A;  2XC5 L;  3TGF A;  2RNL A;  2WPK E;  3FFG L;  5JBC E;  1CEJ A;  1FFM A;  3LN1 A;  1ATB A;  4ISH L;  1NFU B;  5JB9 E;  3KQB L;  2BQ6 A;  2AYL A;  2PR3 B;  3QMO A;  2W2P E;  3QCW A;  3FBY A;  3ZYG A;  2UWO B;  1WU1 B;  1CCF A;  2Y38 A;  1KIG L;  2YGQ A;  4ISI L;  4RUT A;  2VWO L;  3ZYI B;  2EI8 B;  2XBW L;  1MOX C;  4Y6D B;  3TH3 L;  2BOX A;  1LMJ A;  2XBY L;  3POY A;  4MMZ B;  1I0U A;  1HAE A;  3HS6 A;  2Y5H L;  4RRY A;  2BQW A;  1HT8 A;  2Y80 B;  4RRW A;  2J34 B;  1HZ8 A;  1YGC L;  4BTT A;  3S6X A;  2K2T A;  5IKT A;  5L30 L;  2W2N E;  1C5M F;  1CQE A;  3C9A C;  5KIR A;  2WPM E;  3TK5 B;  1XFE A;  4LMF A;  4Y7B B;  4Y76 B;  1WHE A;  1TPG A;  1LPK A;  2MHP A;  4D90 A;  1F0S B;  1IGZ A;  3F6U L;  3LTF B;  1IGX A;  2NPR A;  2FZZ L;  1NFX B;  4CSY A;  3CEN L;  3GCW E;  1HJ7 A;  3TBD A;  1NZI A;  1TLE A;  2PHB B;  2VWN L;  1P0S L;  1IQF L;  1PXX A;  1IQG L;  2UWP B;  1Z6E L;  3V64 C;  1KLI L;  1APQ A;  2XC4 L;  1IP0 A;  2VH6 B;  3NTB A;  1EBV A;  3LTG D;  1X7A L;  1FJS L;  1G1R A;  2I9B A;  3HO4 A;  4YZU B;  3P5B L;  1DQB A;  2P95 L;  1IOX A;  3KL6 B;  2Q1J B;  5CKM A;  1Z6C A;  2KNI A;  5L2Z L;  3SOQ A;  1DDX A;  1JV2 B;  4ZHA B;  2P3U A;  3LIW B;  2BOK L;  4NG9 L;  1IQK L;  3N8Y B;  2W2Q E;  2GD4 A;  2TGF A;  3HO3 A;  2VH0 B;  4E1G A;  1ADX A;  4X8V L;  2VVC K;  3U73 A;  4XBM A;  4X8T L;  2YGP A;  3FCS B;  1ATD A;  4MMX B;  2P3F N;  2BQ7 A;  3IJE B;  2F9B L;  1AUT L;  2ADX A;  2G00 L;  5JVZ A;  1UZK A;  5KN5 C;  1RFN B;  2H9E C;  5IKV A;  4C16 A;  2WZP P;  1G2M B;  1EGF A;  2P16 L;  5IKQ A;  3HS5 A;  3MDL A;  1MQ5 L;  1FF7 A;  3DEM A;  4RRX A;  1EPH A;  3GIS X;  2FD6 A;  2VJ3 A;  2Y5G L;  3TZI A;  1NQL B;  4CUF A;  1IQE L;  4BXS A;  1N1I A;  4A7I A;  4PH9 A;  1FAK L;  2WPJ E;  1N7D A;  3SOV A;  2OYE P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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