2P94L

Factor xa in complex with the inhibitor 3-chloro-n-((1r,2s)-2-(4-(2-oxopyridin-1(2h)-yl)benzamido)cyclohexyl)-1h-indole-6-carboxamide
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Factor Xa
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2p94L00
3N8XA 2WPHE 2I9AA 5I46L 2I9BA 3QH0A 1JL9A 3SOQA 1FAKL 1FSBA 1OB1C 1XDTR 1WU1B 3ZYJB 1B9WA 3N8YB 3TGFA 2VH0B 2J38B 2Y81B 4G1MB 1HT8A 3ELAL 3LTGD 3FBYA 1PGEA 2BQ6A 2OYUP 4O1ZA 1M1XB 4FM5A 3KQCL 6COXA 4RUTA 1IQIL 1EPIA 5JBAE 3QMOA 2PHBB 2B7DL 1JV2B 2BOUA 1IOEL 1PFXL 1MQ6L 4X8UL 3HO3A 1YUGA 1U67A 2BQWA 2VVVL 3U73A 5JB9E 1KSNB 3HS7A 3BPSE 1IJQA 1F7MA 4MMZB 3V65B 1FE2A 1LMJA 4Y76B 1UZPA 1J9CL 3IJEB 2H9EL 1WHEA 2XBVL 2WPJE 5IKVA 4BTUA 1EPJA 4COXA 5JW1A 3HO5A 3CENL 1AUTL 2BMGA 4D90A 2DDUA 3M37L 4E1GA 5CKMA 4TGFA 1XKAL 1IOXA 3QCWA 2XBYL 1HCGB 3C9AC 4PH9A 3LIWB 4JZEL 2XC4L 5KIRA 4XBMA 4AQTA 2WPME 3V64C 3ZYIB 3TZIA 1DVAL 3F6UL 1BF9A 1YO8A 4RRZA 5JBBE 4Y6DB 2KL7A 2MGRA 1N7DA 4JYVL 3KRKA 1TLEA 5JVYA 2VWOL 2VWNL 2BO2A 2W2NE 2Y5GL 4ZXYL 1HREA 2Y82B 3NT1A 4RRXA 1N1IA 4ZAEB 2KB9A 1ATDA 1HAEA 1CVWL 3N8WA 3NTBA 1KLJL 3KQBL 3GCXE 4ZHAB 1ATEA 1XFEA 3PGHA 1HJ7A 4YT6L 5JB8E 1IQLL 1HZ8A 3EGFA 1W8BL 1IQKL 1U8CB 2J34B 3LC5B 1IQEL 4CUDA 1PXXA 1EMNA 1G1TA 2CJIB 2WG4B 1V3XB 5IKTA 1MOXC 1Z6CA 3OLUA 2UWLB 2W2PE 2EI7B 3FCSB 2G00L 2P3TA 4YT7L 3ASIA 1W7XL 3LN1A 1COUA 4BDXA 3Q3KB 2FZZL 4CUFA 1URKA 3GISX 1IQNL 1LQDA 2XC5L 5IKRA 3H5CB 4NA9L 2K2TA 4X8SL 2WPIE 1IQGL 4CSYA 3N8ZA 2VWLL 5K0HB 2W2OE 1YUFA 2WPKE 1ADXA 1HAFA 2AYLA 1IQFL 2BOXA 3M36L 1NFUB 1F0SB 4ISIL 4BTIA 1IQML 4X8VL 1L5GB 3ZYGA 2WFXB 2M74A 3N8WB 2BOHA 3LTFB 3TH3L 2VVUL 1LPKA 1JBUL 3CA7A 1QFKL 3ENSA 2P93L 3R05A 3TK6B 1FAXL 4YZUB 1LPZA 5CKNA 1SZBA 2YGOA 3MQEA 4JYUL 3TBDA 3POYA 5F1AA 4ZH8B 3HPTA 4OTJA 4Y7AB 1IQJL 2J4IB 2P3UA 1IVOC 1K36A 1O5DL 2FLRL 1EQHA 1PTHA 1P9JA 3P5BL 4RRYA 3DEMA 2P26A 5F19A 5KN5C 2WFTA 3KQDL 3OLTA 4ISHL 4BDWA 2MHPA 4MMXB 3KL6B 1DIYA 1F0RB 1FFMA 2YGPA 2PUQL 5CKQA 4M11A 2Y38A 3FFGL 2J95B 2UWOB 2JKHL 1EPGA 2VH6B 1NZIA 3BT2A 1CCVA 4RRWA 1CQEA 5JBCE 4X8TL 4Y7BB 1NFYB 4JZDL 4BTTA 1X7AL 3KK6A 1EMOA 5EGMB 2UWPB 2P94L 3TK5B 5JVZA 1DQBA 5CISA 4Y71B 2W3IB 3KCGL 1Q4GA 4BXWA 1CEJA 2WYGB 4CUEA 3NTGA 4OTYA 2KV4A 1L3YA 2FD6A 3MDLA 2WPLE 3CFWA 3SOVA 2P16L 4XL1A 1IP0A 2F9BL 1CX2A 3F1SB 1UZKA 3HS5A 2RHPA 1ATBA 4Z6AL 1TOZA 3SOBB 2W2QE 2TGFA 2BQ7A 2VVCK 1MQ5L 2VWMK 1G1QA 1TPGA 1K37A 1PRHA 1HX2A 1G2LB 1UZJA 2BZ6L 1XKBA 1C5MF 2Y5FL 1FF7A 1IGXA 1EPHA 2W2ME 3LC3B 1IQHL 1UZQA 2OYEP 2W86A 2GD4A 3KQEL 1CCFA 1FJSL 3U7UG 1YUKB 4JZFL 3GCWE 4NGAL 1LPGA 2P3FN 1NPEB 2BOKL 1Z6EL 2Y5HL 4Z0KB 2P3FL 1KLOA 5L2YL 4M10A 4Z0LA 5FDQA 3N8VA 2P28B 1G2MB 2D1JB 1I0UA 3NJPC 1NFWB 3IITB 2XBWL 4BXSA 3HO4A 2Q1JB 2RA0L 1DX5I 2VJ3A 2J94B 1DDXA 3LN0A 5IKQA 1F7EA 1CVUA 2MGPA 4XLWA 1KIGL 1G1RA 2P95L 3N8YA 1WHFA 2WYJB 5COXA 1HT5A 2FLBL 2WG3C 1APQA 1G1SA 1GK5A 1NFXB 1P0SL 2PR3B 1ZAQA 2EI6B 5E8DA 3Q7DA 1APOA 5L30L 1RFNB 3LAQA 1EBVA 2XBXL 3SW2A 2W26B 1HRFA 1EQGA 4MMYB 4LORA 3BT1A 3CS7L 4A7IA 2Y7ZB 4O02B 2ADXA 2Y7XB 1EZQB 2Y80B 4LMFA 2EI8B 4NG9L 1EAIC 4Y79B 1IGZA 2RNLA 2XC0L 1EGFA 4D0FA 3HS6A 4RS0A 1ATAA 2K2SB 1NT0A 4ZXXL 4C16A 3RR3A 1YGCL 2FLGA 2J2UB 1KLIL 2W3KB 5L2ZL 1NQLB 2NPRA 4D0EA 3K9XA 1A3PA
chains in the Genus database with same CATH superfamily
1V1IA 3N8XA 2WPHE 2I9AA 5I46L 2I9BA 3QH0A 1JL9A 3SOQA 1FAKL 1FSBA 1OB1C 1XDTR 1WU1B 3ZYJB 1B9WA 3N8YB 3TGFA 2VH0B 2J38B 2Y81B 4G1MB 1HT8A 3ELAL 3LTGD 3FBYA 1PGEA 2BQ6A 2OYUP 4O1ZA 1M1XB 4FM5A 2HORA 3KQCL 6COXA 2BT8A 4RUTA 1IQIL 1EPIA 5JBAE 3QMOA 2PHBB 2B7DL 1JV2B 2BOUA 1IOEL 1PFXL 1MQ6L 4X8UL 3HO3A 1YUGA 1U67A 2BQWA 2VVVL 3U73A 5JB9E 1KSNB 3HS7A 3BPSE 1IJQA 1F7MA 4MMZB 3V65B 4GU3A 1FE2A 1LMJA 4Y76B 1UZPA 1J9CL 3IJEB 2H9EL 1WHEA 2XBVL 1LK9A 2WPJE 5IKVA 4BTUA 1EPJA 4COXA 5JW1A 3HO5A 3CENL 1AUTL 2BMGA 4D90A 2DDUA 3M37L 4E1GA 5CKMA 4TGFA 1XKAL 1IOXA 3QCWA 2XBYL 1HCGB 3C9AC 4PH9A 3LIWB 4JZEL 2XC4L 5KIRA 4XBMA 4AQTA 2WPME 3V64C 3ZYIB 3TZIA 1DVAL 3F6UL 1BF9A 1YO8A 4RRZA 5JBBE 4Y6DB 2WZPP 2KL7A 2MGRA 1N7DA 4JYVL 3KRKA 1TLEA 5JVYA 2VWOL 2VWNL 2BO2A 2W2NE 2Y5GL 4ZXYL 1HREA 2HOXA 2Y82B 3NT1A 4RRXA 1N1IA 4ZAEB 2KB9A 1ATDA 1HAEA 1CVWL 3N8WA 3NTBA 1KLJL 3KQBL 3GCXE 4ZHAB 1ATEA 1XFEA 3PGHA 1HJ7A 4YT6L 5JB8E 1IQLL 1HZ8A 3EGFA 1W8BL 1IQKL 1U8CB 2J34B 3LC5B 1IQEL 4CUDA 1PXXA 2BSFA 2KNIA 1EMNA 1G1TA 2CJIB 2WG4B 1V3XB 5IKTA 1MOXC 1Z6CA 3OLUA 2UWLB 2W2PE 2EI7B 3FCSB 2G00L 2P3TA 4YT7L 3ASIA 1W7XL 3LN1A 1COUA 4BDXA 3Q3KB 2FZZL 4CUFA 1URKA 3GISX 1IQNL 1LQDA 2XC5L 5IKRA 3H5CB 4NA9L 2K2TA 4X8SL 2WPIE 1IQGL 2VRSA 4CSYA 3N8ZA 2VWLL 5K0HB 2W2OE 1YUFA 2WPKE 1ADXA 1HAFA 1KKEA 2AYLA 1IQFL 2BOXA 3M36L 1NFUB 1F0SB 4ISIL 4BTIA 1IQML 4X8VL 1L5GB 3ZYGA 2WFXB 2M74A 3N8WB 2BOHA 3LTFB 3TH3L 2VVUL 1LPKA 4GU4A 1JBUL 3CA7A 1QFKL 3ENSA 2P93L 3R05A 3TK6B 1FAXL 4YZUB 1LPZA 5CKNA 1SZBA 2YGOA 3MQEA 4JYUL 3TBDA 3POYA 5F1AA 2H9EC 4ZH8B 3HPTA 4OTJA 4Y7AB 1IQJL 2J4IB 2P3UA 1IVOC 1K36A 1O5DL 2FLRL 1EQHA 1PTHA 1P9JA 3P5BL 4RRYA 3DEMA 2P26A 5F19A 5KN5C 2WFTA 3KQDL 3OLTA 4ISHL 1QIUA 4BDWA 2MHPA 4MMXB 3KL6B 1DIYA 1F0RB 1FFMA 2YGPA 2PUQL 5CKQA 4M11A 2Y38A 3FFGL 2J95B 2UWOB 2JKHL 1EPGA 2VH6B 1NZIA 3BT2A 1CCVA 4RRWA 1CQEA 5JBCE 4X8TL 4Y7BB 2BT7A 1NFYB 4JZDL 4BTTA 1X7AL 3KK6A 1EMOA 5EGMB 2UWPB 2P94L 3TK5B 5JVZA 1DQBA 5CISA 4Y71B 2W3IB 3KCGL 1Q4GA 2YGQA 4BXWA 1CEJA 2WYGB 4CUEA 3NTGA 4OTYA 2KV4A 3S6XA 1L3YA 2FD6A 3MDLA 2WPLE 3CFWA 3SOVA 2P16L 4XL1A 4A94C 1IP0A 2F9BL 1CX2A 3F1SB 1UZKA 3HS5A 2RHPA 1ATBA 4Z6AL 1TOZA 3SOBB 2W2QE 2TGFA 2BQ7A 2VVCK 1MQ5L 2VWMK 1G1QA 1TPGA 1K37A 1PRHA 1HX2A 1G2LB 1UZJA 2BZ6L 1XKBA 1C5MF 2Y5FL 1FF7A 1IGXA 1EPHA 2W2ME 1V1HA 3LC3B 1IQHL 1UZQA 1LMMA 2OYEP 2W86A 2GD4A 3KQEL 1CCFA 1FJSL 3U7UG 1YUKB 4JZFL 3GCWE 4NGAL 1LPGA 2P3FN 2JJLA 1NPEB 2BOKL 1Z6EL 2Y5HL 4Z0KB 2P3FL 1KLOA 5L2YL 4M10A 4Z0LA 5FDQA 3N8VA 2P28B 1G2MB 2D1JB 1I0UA 3NJPC 1NFWB 3IITB 2XBWL 4BXSA 3HO4A 2Q1JB 2RA0L 1DX5I 2VJ3A 2J94B 1DDXA 3LN0A 5IKQA 1F7EA 1CVUA 2MGPA 4XLWA 1KIGL 1G1RA 2P95L 3N8YA 1WHFA 2WYJB 5COXA 1HT5A 2FLBL 2WG3C 1APQA 1G1SA 1GK5A 1NFXB 1P0SL 2PR3B 1ZAQA 2EI6B 5E8DA 3Q7DA 1APOA 5L30L 1RFNB 3LAQA 1EBVA 2XBXL 3SW2A 2W26B 1HRFA 1EQGA 4MMYB 4LORA 3BT1A 3CS7L 4A7IA 2Y7ZB 4O02B 2ADXA 2Y7XB 1EZQB 2Y80B 4LMFA 2EI8B 4NG9L 1EAIC 4Y79B 1IGZA 2RNLA 2XC0L 1EGFA 4D0FA 3HS6A 4RS0A 1ATAA 2K2SB 1NT0A 4ZXXL 4C16A 3RR3A 1YGCL 2FLGA 2J2UB 1KLIL 2W3KB 5L2ZL 1NQLB 2NPRA 4D0EA 3K9XA 1A3PA
chains in the Genus database with same CATH topology
3N8XA 2WPHE 2I9AA 5I46L 2I9BA 3QH0A 1JL9A 3SOQA 1FAKL 1FSBA 1OB1C 1XDTR 1WU1B 3ZYJB 1B9WA 3N8YB 3TGFA 2VH0B 2J38B 2Y81B 4G1MB 1HT8A 3ELAL 3LTGD 3FBYA 1PGEA 2BQ6A 2OYUP 4O1ZA 1M1XB 4FM5A 3KQCL 6COXA 4RUTA 1IQIL 1EPIA 5JBAE 3QMOA 2PHBB 2B7DL 1JV2B 2BOUA 1IOEL 1PFXL 1MQ6L 4X8UL 3HO3A 1YUGA 1U67A 2BQWA 2VVVL 3U73A 5JB9E 1KSNB 3HS7A 3BPSE 1IJQA 1F7MA 4MMZB 3V65B 1FE2A 1LMJA 4Y76B 1UZPA 1J9CL 3IJEB 2H9EL 1WHEA 2XBVL 2WPJE 5IKVA 4BTUA 1EPJA 4COXA 5JW1A 3HO5A 3CENL 1AUTL 2BMGA 4D90A 2DDUA 3M37L 4E1GA 5CKMA 4TGFA 1XKAL 1IOXA 3QCWA 2XBYL 1HCGB 3C9AC 4PH9A 3LIWB 4JZEL 2XC4L 5KIRA 4XBMA 4AQTA 2WPME 3V64C 3ZYIB 3TZIA 1DVAL 3F6UL 1BF9A 1YO8A 4RRZA 5JBBE 4Y6DB 2WZPP 2KL7A 2MGRA 1N7DA 4JYVL 3KRKA 1TLEA 5JVYA 2VWOL 2VWNL 2BO2A 2W2NE 2Y5GL 4ZXYL 1HREA 2Y82B 3NT1A 4RRXA 1N1IA 4ZAEB 2KB9A 1ATDA 1HAEA 1CVWL 3N8WA 3NTBA 1KLJL 3KQBL 3GCXE 4ZHAB 1ATEA 1XFEA 3PGHA 1HJ7A 4YT6L 5JB8E 1IQLL 1HZ8A 3EGFA 1W8BL 1IQKL 1U8CB 2J34B 3LC5B 1IQEL 4CUDA 1PXXA 2KNIA 1EMNA 1G1TA 2CJIB 2WG4B 1V3XB 5IKTA 1MOXC 1Z6CA 3OLUA 2UWLB 2W2PE 2EI7B 3FCSB 2G00L 2P3TA 4YT7L 3ASIA 1W7XL 3LN1A 1COUA 4BDXA 3Q3KB 2FZZL 4CUFA 1URKA 3GISX 1IQNL 1LQDA 2XC5L 5IKRA 3H5CB 4NA9L 2K2TA 4X8SL 2WPIE 1IQGL 4CSYA 3N8ZA 2VWLL 5K0HB 2W2OE 1YUFA 2WPKE 1ADXA 1HAFA 2AYLA 1IQFL 2BOXA 3M36L 1NFUB 1F0SB 4ISIL 4BTIA 1IQML 4X8VL 1L5GB 3ZYGA 2WFXB 2M74A 3N8WB 2BOHA 3LTFB 3TH3L 2VVUL 1LPKA 1JBUL 3CA7A 1QFKL 3ENSA 2P93L 3R05A 3TK6B 1FAXL 4YZUB 1LPZA 5CKNA 1SZBA 2YGOA 3MQEA 4JYUL 3TBDA 3POYA 5F1AA 2H9EC 4ZH8B 3HPTA 4OTJA 4Y7AB 1IQJL 2J4IB 2P3UA 1IVOC 1K36A 1O5DL 2FLRL 1EQHA 1PTHA 1P9JA 3P5BL 4RRYA 3DEMA 2P26A 5F19A 5KN5C 2WFTA 3KQDL 3OLTA 4ISHL 4BDWA 2MHPA 4MMXB 3KL6B 1DIYA 1F0RB 1FFMA 2YGPA 2PUQL 5CKQA 4M11A 2Y38A 3FFGL 2J95B 2UWOB 2JKHL 1EPGA 2VH6B 1NZIA 3BT2A 1CCVA 4RRWA 1CQEA 5JBCE 4X8TL 4Y7BB 1NFYB 4JZDL 4BTTA 1X7AL 3KK6A 1EMOA 5EGMB 2UWPB 2P94L 3TK5B 5JVZA 1DQBA 5CISA 4Y71B 2W3IB 3KCGL 1Q4GA 2YGQA 4BXWA 1CEJA 2WYGB 4CUEA 3NTGA 4OTYA 2KV4A 3S6XA 1L3YA 2FD6A 3MDLA 2WPLE 3CFWA 3SOVA 2P16L 4XL1A 4A94C 1IP0A 2F9BL 1CX2A 3F1SB 1UZKA 3HS5A 2RHPA 1ATBA 4Z6AL 1TOZA 3SOBB 2W2QE 2TGFA 2BQ7A 2VVCK 1MQ5L 2VWMK 1G1QA 1TPGA 1K37A 1PRHA 1HX2A 1G2LB 1UZJA 2BZ6L 1XKBA 1C5MF 2Y5FL 1FF7A 1IGXA 1EPHA 2W2ME 3LC3B 1IQHL 1UZQA 1LMMA 2OYEP 2W86A 2GD4A 3KQEL 1CCFA 1FJSL 3U7UG 1YUKB 4JZFL 3GCWE 4NGAL 1LPGA 2P3FN 1NPEB 2BOKL 1Z6EL 2Y5HL 4Z0KB 2P3FL 1KLOA 5L2YL 4M10A 4Z0LA 5FDQA 3N8VA 2P28B 1G2MB 2D1JB 1I0UA 3NJPC 1NFWB 3IITB 2XBWL 4BXSA 3HO4A 2Q1JB 2RA0L 1DX5I 2VJ3A 2J94B 1DDXA 3LN0A 5IKQA 1F7EA 1CVUA 2MGPA 4XLWA 1KIGL 1G1RA 2P95L 3N8YA 1WHFA 2WYJB 5COXA 1HT5A 2FLBL 2WG3C 1APQA 1G1SA 1GK5A 1NFXB 1P0SL 2PR3B 1ZAQA 2EI6B 5E8DA 3Q7DA 1APOA 5L30L 1RFNB 3LAQA 1EBVA 2XBXL 3SW2A 2W26B 1HRFA 1EQGA 4MMYB 4LORA 3BT1A 3CS7L 4A7IA 2Y7ZB 4O02B 2ADXA 2Y7XB 1EZQB 2Y80B 4LMFA 2EI8B 4NG9L 1EAIC 4Y79B 1IGZA 2RNLA 2XC0L 1EGFA 4D0FA 3HS6A 4RS0A 1ATAA 2K2SB 1NT0A 4ZXXL 4C16A 3RR3A 1YGCL 2FLGA 2J2UB 1KLIL 2W3KB 5L2ZL 1NQLB 2NPRA 4D0EA 3K9XA 1A3PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N8X A;  2WPH E;  2I9A A;  5I46 L;  2I9B A;  3QH0 A;  1JL9 A;  3SOQ A;  1FAK L;  1FSB A;  1OB1 C;  1XDT R;  1WU1 B;  3ZYJ B;  1B9W A;  3N8Y B;  3TGF A;  2VH0 B;  2J38 B;  2Y81 B;  4G1M B;  1HT8 A;  3ELA L;  3LTG D;  3FBY A;  1PGE A;  2BQ6 A;  2OYU P;  4O1Z A;  1M1X B;  4FM5 A;  3KQC L;  6COX A;  4RUT A;  1IQI L;  1EPI A;  5JBA E;  3QMO A;  2PHB B;  2B7D L;  1JV2 B;  2BOU A;  1IOE L;  1PFX L;  1MQ6 L;  4X8U L;  3HO3 A;  1YUG A;  1U67 A;  2BQW A;  2VVV L;  3U73 A;  5JB9 E;  1KSN B;  3HS7 A;  3BPS E;  1IJQ A;  1F7M A;  4MMZ B;  3V65 B;  1FE2 A;  1LMJ A;  4Y76 B;  1UZP A;  1J9C L;  3IJE B;  2H9E L;  1WHE A;  2XBV L;  2WPJ E;  5IKV A;  4BTU A;  1EPJ A;  4COX A;  5JW1 A;  3HO5 A;  3CEN L;  1AUT L;  2BMG A;  4D90 A;  2DDU A;  3M37 L;  4E1G A;  5CKM A;  4TGF A;  1XKA L;  1IOX A;  3QCW A;  2XBY L;  1HCG B;  3C9A C;  4PH9 A;  3LIW B;  4JZE L;  2XC4 L;  5KIR A;  4XBM A;  4AQT A;  2WPM E;  3V64 C;  3ZYI B;  3TZI A;  1DVA L;  3F6U L;  1BF9 A;  1YO8 A;  4RRZ A;  5JBB E;  4Y6D B;  2KL7 A;  2MGR A;  1N7D A;  4JYV L;  3KRK A;  1TLE A;  5JVY A;  2VWO L;  2VWN L;  2BO2 A;  2W2N E;  2Y5G L;  4ZXY L;  1HRE A;  2Y82 B;  3NT1 A;  4RRX A;  1N1I A;  4ZAE B;  2KB9 A;  1ATD A;  1HAE A;  1CVW L;  3N8W A;  3NTB A;  1KLJ L;  3KQB L;  3GCX E;  4ZHA B;  1ATE A;  1XFE A;  3PGH A;  1HJ7 A;  4YT6 L;  5JB8 E;  1IQL L;  1HZ8 A;  3EGF A;  1W8B L;  1IQK L;  1U8C B;  2J34 B;  3LC5 B;  1IQE L;  4CUD A;  1PXX A;  1EMN A;  1G1T A;  2CJI B;  2WG4 B;  1V3X B;  5IKT A;  1MOX C;  1Z6C A;  3OLU A;  2UWL B;  2W2P E;  2EI7 B;  3FCS B;  2G00 L;  2P3T A;  4YT7 L;  3ASI A;  1W7X L;  3LN1 A;  1COU A;  4BDX A;  3Q3K B;  2FZZ L;  4CUF A;  1URK A;  3GIS X;  1IQN L;  1LQD A;  2XC5 L;  5IKR A;  3H5C B;  4NA9 L;  2K2T A;  4X8S L;  2WPI E;  1IQG L;  4CSY A;  3N8Z A;  2VWL L;  5K0H B;  2W2O E;  1YUF A;  2WPK E;  1ADX A;  1HAF A;  2AYL A;  1IQF L;  2BOX A;  3M36 L;  1NFU B;  1F0S B;  4ISI L;  4BTI A;  1IQM L;  4X8V L;  1L5G B;  3ZYG A;  2WFX B;  2M74 A;  3N8W B;  2BOH A;  3LTF B;  3TH3 L;  2VVU L;  1LPK A;  1JBU L;  3CA7 A;  1QFK L;  3ENS A;  2P93 L;  3R05 A;  3TK6 B;  1FAX L;  4YZU B;  1LPZ A;  5CKN A;  1SZB A;  2YGO A;  3MQE A;  4JYU L;  3TBD A;  3POY A;  5F1A A;  4ZH8 B;  3HPT A;  4OTJ A;  4Y7A B;  1IQJ L;  2J4I B;  2P3U A;  1IVO C;  1K36 A;  1O5D L;  2FLR L;  1EQH A;  1PTH A;  1P9J A;  3P5B L;  4RRY A;  3DEM A;  2P26 A;  5F19 A;  5KN5 C;  2WFT A;  3KQD L;  3OLT A;  4ISH L;  4BDW A;  2MHP A;  4MMX B;  3KL6 B;  1DIY A;  1F0R B;  1FFM A;  2YGP A;  2PUQ L;  5CKQ A;  4M11 A;  2Y38 A;  3FFG L;  2J95 B;  2UWO B;  2JKH L;  1EPG A;  2VH6 B;  1NZI A;  3BT2 A;  1CCV A;  4RRW A;  1CQE A;  5JBC E;  4X8T L;  4Y7B B;  1NFY B;  4JZD L;  4BTT A;  1X7A L;  3KK6 A;  1EMO A;  5EGM B;  2UWP B;  2P94 L;  3TK5 B;  5JVZ A;  1DQB A;  5CIS A;  4Y71 B;  2W3I B;  3KCG L;  1Q4G A;  4BXW A;  1CEJ A;  2WYG B;  4CUE A;  3NTG A;  4OTY A;  2KV4 A;  1L3Y A;  2FD6 A;  3MDL A;  2WPL E;  3CFW A;  3SOV A;  2P16 L;  4XL1 A;  1IP0 A;  2F9B L;  1CX2 A;  3F1S B;  1UZK A;  3HS5 A;  2RHP A;  1ATB A;  4Z6A L;  1TOZ A;  3SOB B;  2W2Q E;  2TGF A;  2BQ7 A;  2VVC K;  1MQ5 L;  2VWM K;  1G1Q A;  1TPG A;  1K37 A;  1PRH A;  1HX2 A;  1G2L B;  1UZJ A;  2BZ6 L;  1XKB A;  1C5M F;  2Y5F L;  1FF7 A;  1IGX A;  1EPH A;  2W2M E;  3LC3 B;  1IQH L;  1UZQ A;  2OYE P;  2W86 A;  2GD4 A;  3KQE L;  1CCF A;  1FJS L;  3U7U G;  1YUK B;  4JZF L;  3GCW E;  4NGA L;  1LPG A;  2P3F N;  1NPE B;  2BOK L;  1Z6E L;  2Y5H L;  4Z0K B;  2P3F L;  1KLO A;  5L2Y L;  4M10 A;  4Z0L A;  5FDQ A;  3N8V A;  2P28 B;  1G2M B;  2D1J B;  1I0U A;  3NJP C;  1NFW B;  3IIT B;  2XBW L;  4BXS A;  3HO4 A;  2Q1J B;  2RA0 L;  1DX5 I;  2VJ3 A;  2J94 B;  1DDX A;  3LN0 A;  5IKQ A;  1F7E A;  1CVU A;  2MGP A;  4XLW A;  1KIG L;  1G1R A;  2P95 L;  3N8Y A;  1WHF A;  2WYJ B;  5COX A;  1HT5 A;  2FLB L;  2WG3 C;  1APQ A;  1G1S A;  1GK5 A;  1NFX B;  1P0S L;  2PR3 B;  1ZAQ A;  2EI6 B;  5E8D A;  3Q7D A;  1APO A;  5L30 L;  1RFN B;  3LAQ A;  1EBV A;  2XBX L;  3SW2 A;  2W26 B;  1HRF A;  1EQG A;  4MMY B;  4LOR A;  3BT1 A;  3CS7 L;  4A7I A;  2Y7Z B;  4O02 B;  2ADX A;  2Y7X B;  1EZQ B;  2Y80 B;  4LMF A;  2EI8 B;  4NG9 L;  1EAI C;  4Y79 B;  1IGZ A;  2RNL A;  2XC0 L;  1EGF A;  4D0F A;  3HS6 A;  4RS0 A;  1ATA A;  2K2S B;  1NT0 A;  4ZXX L;  4C16 A;  3RR3 A;  1YGC L;  2FLG A;  2J2U B;  1KLI L;  2W3K B;  5L2Z L;  1NQL B;  2NPR A;  4D0E A;  3K9X A;  1A3P A; 
#chains in the Genus database with same CATH topology
 1V1I A;  3N8X A;  2WPH E;  2I9A A;  5I46 L;  2I9B A;  3QH0 A;  1JL9 A;  3SOQ A;  1FAK L;  1FSB A;  1OB1 C;  1XDT R;  1WU1 B;  3ZYJ B;  1B9W A;  3N8Y B;  3TGF A;  2VH0 B;  2J38 B;  2Y81 B;  4G1M B;  1HT8 A;  3ELA L;  3LTG D;  3FBY A;  1PGE A;  2BQ6 A;  2OYU P;  4O1Z A;  1M1X B;  4FM5 A;  2HOR A;  3KQC L;  6COX A;  2BT8 A;  4RUT A;  1IQI L;  1EPI A;  5JBA E;  3QMO A;  2PHB B;  2B7D L;  1JV2 B;  2BOU A;  1IOE L;  1PFX L;  1MQ6 L;  4X8U L;  3HO3 A;  1YUG A;  1U67 A;  2BQW A;  2VVV L;  3U73 A;  5JB9 E;  1KSN B;  3HS7 A;  3BPS E;  1IJQ A;  1F7M A;  4MMZ B;  3V65 B;  4GU3 A;  1FE2 A;  1LMJ A;  4Y76 B;  1UZP A;  1J9C L;  3IJE B;  2H9E L;  1WHE A;  2XBV L;  1LK9 A;  2WPJ E;  5IKV A;  4BTU A;  1EPJ A;  4COX A;  5JW1 A;  3HO5 A;  3CEN L;  1AUT L;  2BMG A;  4D90 A;  2DDU A;  3M37 L;  4E1G A;  5CKM A;  4TGF A;  1XKA L;  1IOX A;  3QCW A;  2XBY L;  1HCG B;  3C9A C;  4PH9 A;  3LIW B;  4JZE L;  2XC4 L;  5KIR A;  4XBM A;  4AQT A;  2WPM E;  3V64 C;  3ZYI B;  3TZI A;  1DVA L;  3F6U L;  1BF9 A;  1YO8 A;  4RRZ A;  5JBB E;  4Y6D B;  2WZP P;  2KL7 A;  2MGR A;  1N7D A;  4JYV L;  3KRK A;  1TLE A;  5JVY A;  2VWO L;  2VWN L;  2BO2 A;  2W2N E;  2Y5G L;  4ZXY L;  1HRE A;  2HOX A;  2Y82 B;  3NT1 A;  4RRX A;  1N1I A;  4ZAE B;  2KB9 A;  1ATD A;  1HAE A;  1CVW L;  3N8W A;  3NTB A;  1KLJ L;  3KQB L;  3GCX E;  4ZHA B;  1ATE A;  1XFE A;  3PGH A;  1HJ7 A;  4YT6 L;  5JB8 E;  1IQL L;  1HZ8 A;  3EGF A;  1W8B L;  1IQK L;  1U8C B;  2J34 B;  3LC5 B;  1IQE L;  4CUD A;  1PXX A;  2BSF A;  2KNI A;  1EMN A;  1G1T A;  2CJI B;  2WG4 B;  1V3X B;  5IKT A;  1MOX C;  1Z6C A;  3OLU A;  2UWL B;  2W2P E;  2EI7 B;  3FCS B;  2G00 L;  2P3T A;  4YT7 L;  3ASI A;  1W7X L;  3LN1 A;  1COU A;  4BDX A;  3Q3K B;  2FZZ L;  4CUF A;  1URK A;  3GIS X;  1IQN L;  1LQD A;  2XC5 L;  5IKR A;  3H5C B;  4NA9 L;  2K2T A;  4X8S L;  2WPI E;  1IQG L;  2VRS A;  4CSY A;  3N8Z A;  2VWL L;  5K0H B;  2W2O E;  1YUF A;  2WPK E;  1ADX A;  1HAF A;  1KKE A;  2AYL A;  1IQF L;  2BOX A;  3M36 L;  1NFU B;  1F0S B;  4ISI L;  4BTI A;  1IQM L;  4X8V L;  1L5G B;  3ZYG A;  2WFX B;  2M74 A;  3N8W B;  2BOH A;  3LTF B;  3TH3 L;  2VVU L;  1LPK A;  4GU4 A;  1JBU L;  3CA7 A;  1QFK L;  3ENS A;  2P93 L;  3R05 A;  3TK6 B;  1FAX L;  4YZU B;  1LPZ A;  5CKN A;  1SZB A;  2YGO A;  3MQE A;  4JYU L;  3TBD A;  3POY A;  5F1A A;  2H9E C;  4ZH8 B;  3HPT A;  4OTJ A;  4Y7A B;  1IQJ L;  2J4I B;  2P3U A;  1IVO C;  1K36 A;  1O5D L;  2FLR L;  1EQH A;  1PTH A;  1P9J A;  3P5B L;  4RRY A;  3DEM A;  2P26 A;  5F19 A;  5KN5 C;  2WFT A;  3KQD L;  3OLT A;  4ISH L;  1QIU A;  4BDW A;  2MHP A;  4MMX B;  3KL6 B;  1DIY A;  1F0R B;  1FFM A;  2YGP A;  2PUQ L;  5CKQ A;  4M11 A;  2Y38 A;  3FFG L;  2J95 B;  2UWO B;  2JKH L;  1EPG A;  2VH6 B;  1NZI A;  3BT2 A;  1CCV A;  4RRW A;  1CQE A;  5JBC E;  4X8T L;  4Y7B B;  2BT7 A;  1NFY B;  4JZD L;  4BTT A;  1X7A L;  3KK6 A;  1EMO A;  5EGM B;  2UWP B;  2P94 L;  3TK5 B;  5JVZ A;  1DQB A;  5CIS A;  4Y71 B;  2W3I B;  3KCG L;  1Q4G A;  2YGQ A;  4BXW A;  1CEJ A;  2WYG B;  4CUE A;  3NTG A;  4OTY A;  2KV4 A;  3S6X A;  1L3Y A;  2FD6 A;  3MDL A;  2WPL E;  3CFW A;  3SOV A;  2P16 L;  4XL1 A;  4A94 C;  1IP0 A;  2F9B L;  1CX2 A;  3F1S B;  1UZK A;  3HS5 A;  2RHP A;  1ATB A;  4Z6A L;  1TOZ A;  3SOB B;  2W2Q E;  2TGF A;  2BQ7 A;  2VVC K;  1MQ5 L;  2VWM K;  1G1Q A;  1TPG A;  1K37 A;  1PRH A;  1HX2 A;  1G2L B;  1UZJ A;  2BZ6 L;  1XKB A;  1C5M F;  2Y5F L;  1FF7 A;  1IGX A;  1EPH A;  2W2M E;  1V1H A;  3LC3 B;  1IQH L;  1UZQ A;  1LMM A;  2OYE P;  2W86 A;  2GD4 A;  3KQE L;  1CCF A;  1FJS L;  3U7U G;  1YUK B;  4JZF L;  3GCW E;  4NGA L;  1LPG A;  2P3F N;  2JJL A;  1NPE B;  2BOK L;  1Z6E L;  2Y5H L;  4Z0K B;  2P3F L;  1KLO A;  5L2Y L;  4M10 A;  4Z0L A;  5FDQ A;  3N8V A;  2P28 B;  1G2M B;  2D1J B;  1I0U A;  3NJP C;  1NFW B;  3IIT B;  2XBW L;  4BXS A;  3HO4 A;  2Q1J B;  2RA0 L;  1DX5 I;  2VJ3 A;  2J94 B;  1DDX A;  3LN0 A;  5IKQ A;  1F7E A;  1CVU A;  2MGP A;  4XLW A;  1KIG L;  1G1R A;  2P95 L;  3N8Y A;  1WHF A;  2WYJ B;  5COX A;  1HT5 A;  2FLB L;  2WG3 C;  1APQ A;  1G1S A;  1GK5 A;  1NFX B;  1P0S L;  2PR3 B;  1ZAQ A;  2EI6 B;  5E8D A;  3Q7D A;  1APO A;  5L30 L;  1RFN B;  3LAQ A;  1EBV A;  2XBX L;  3SW2 A;  2W26 B;  1HRF A;  1EQG A;  4MMY B;  4LOR A;  3BT1 A;  3CS7 L;  4A7I A;  2Y7Z B;  4O02 B;  2ADX A;  2Y7X B;  1EZQ B;  2Y80 B;  4LMF A;  2EI8 B;  4NG9 L;  1EAI C;  4Y79 B;  1IGZ A;  2RNL A;  2XC0 L;  1EGF A;  4D0F A;  3HS6 A;  4RS0 A;  1ATA A;  2K2S B;  1NT0 A;  4ZXX L;  4C16 A;  3RR3 A;  1YGC L;  2FLG A;  2J2U B;  1KLI L;  2W3K B;  5L2Z L;  1NQL B;  2NPR A;  4D0E A;  3K9X A;  1A3P A; 
#chains in the Genus database with same CATH homology
 3N8X A;  2WPH E;  2I9A A;  5I46 L;  2I9B A;  3QH0 A;  1JL9 A;  3SOQ A;  1FAK L;  1FSB A;  1OB1 C;  1XDT R;  1WU1 B;  3ZYJ B;  1B9W A;  3N8Y B;  3TGF A;  2VH0 B;  2J38 B;  2Y81 B;  4G1M B;  1HT8 A;  3ELA L;  3LTG D;  3FBY A;  1PGE A;  2BQ6 A;  2OYU P;  4O1Z A;  1M1X B;  4FM5 A;  3KQC L;  6COX A;  4RUT A;  1IQI L;  1EPI A;  5JBA E;  3QMO A;  2PHB B;  2B7D L;  1JV2 B;  2BOU A;  1IOE L;  1PFX L;  1MQ6 L;  4X8U L;  3HO3 A;  1YUG A;  1U67 A;  2BQW A;  2VVV L;  3U73 A;  5JB9 E;  1KSN B;  3HS7 A;  3BPS E;  1IJQ A;  1F7M A;  4MMZ B;  3V65 B;  1FE2 A;  1LMJ A;  4Y76 B;  1UZP A;  1J9C L;  3IJE B;  2H9E L;  1WHE A;  2XBV L;  2WPJ E;  5IKV A;  4BTU A;  1EPJ A;  4COX A;  5JW1 A;  3HO5 A;  3CEN L;  1AUT L;  2BMG A;  4D90 A;  2DDU A;  3M37 L;  4E1G A;  5CKM A;  4TGF A;  1XKA L;  1IOX A;  3QCW A;  2XBY L;  1HCG B;  3C9A C;  4PH9 A;  3LIW B;  4JZE L;  2XC4 L;  5KIR A;  4XBM A;  4AQT A;  2WPM E;  3V64 C;  3ZYI B;  3TZI A;  1DVA L;  3F6U L;  1BF9 A;  1YO8 A;  4RRZ A;  5JBB E;  4Y6D B;  2WZP P;  2KL7 A;  2MGR A;  1N7D A;  4JYV L;  3KRK A;  1TLE A;  5JVY A;  2VWO L;  2VWN L;  2BO2 A;  2W2N E;  2Y5G L;  4ZXY L;  1HRE A;  2Y82 B;  3NT1 A;  4RRX A;  1N1I A;  4ZAE B;  2KB9 A;  1ATD A;  1HAE A;  1CVW L;  3N8W A;  3NTB A;  1KLJ L;  3KQB L;  3GCX E;  4ZHA B;  1ATE A;  1XFE A;  3PGH A;  1HJ7 A;  4YT6 L;  5JB8 E;  1IQL L;  1HZ8 A;  3EGF A;  1W8B L;  1IQK L;  1U8C B;  2J34 B;  3LC5 B;  1IQE L;  4CUD A;  1PXX A;  2KNI A;  1EMN A;  1G1T A;  2CJI B;  2WG4 B;  1V3X B;  5IKT A;  1MOX C;  1Z6C A;  3OLU A;  2UWL B;  2W2P E;  2EI7 B;  3FCS B;  2G00 L;  2P3T A;  4YT7 L;  3ASI A;  1W7X L;  3LN1 A;  1COU A;  4BDX A;  3Q3K B;  2FZZ L;  4CUF A;  1URK A;  3GIS X;  1IQN L;  1LQD A;  2XC5 L;  5IKR A;  3H5C B;  4NA9 L;  2K2T A;  4X8S L;  2WPI E;  1IQG L;  4CSY A;  3N8Z A;  2VWL L;  5K0H B;  2W2O E;  1YUF A;  2WPK E;  1ADX A;  1HAF A;  2AYL A;  1IQF L;  2BOX A;  3M36 L;  1NFU B;  1F0S B;  4ISI L;  4BTI A;  1IQM L;  4X8V L;  1L5G B;  3ZYG A;  2WFX B;  2M74 A;  3N8W B;  2BOH A;  3LTF B;  3TH3 L;  2VVU L;  1LPK A;  1JBU L;  3CA7 A;  1QFK L;  3ENS A;  2P93 L;  3R05 A;  3TK6 B;  1FAX L;  4YZU B;  1LPZ A;  5CKN A;  1SZB A;  2YGO A;  3MQE A;  4JYU L;  3TBD A;  3POY A;  5F1A A;  2H9E C;  4ZH8 B;  3HPT A;  4OTJ A;  4Y7A B;  1IQJ L;  2J4I B;  2P3U A;  1IVO C;  1K36 A;  1O5D L;  2FLR L;  1EQH A;  1PTH A;  1P9J A;  3P5B L;  4RRY A;  3DEM A;  2P26 A;  5F19 A;  5KN5 C;  2WFT A;  3KQD L;  3OLT A;  4ISH L;  4BDW A;  2MHP A;  4MMX B;  3KL6 B;  1DIY A;  1F0R B;  1FFM A;  2YGP A;  2PUQ L;  5CKQ A;  4M11 A;  2Y38 A;  3FFG L;  2J95 B;  2UWO B;  2JKH L;  1EPG A;  2VH6 B;  1NZI A;  3BT2 A;  1CCV A;  4RRW A;  1CQE A;  5JBC E;  4X8T L;  4Y7B B;  1NFY B;  4JZD L;  4BTT A;  1X7A L;  3KK6 A;  1EMO A;  5EGM B;  2UWP B;  2P94 L;  3TK5 B;  5JVZ A;  1DQB A;  5CIS A;  4Y71 B;  2W3I B;  3KCG L;  1Q4G A;  2YGQ A;  4BXW A;  1CEJ A;  2WYG B;  4CUE A;  3NTG A;  4OTY A;  2KV4 A;  3S6X A;  1L3Y A;  2FD6 A;  3MDL A;  2WPL E;  3CFW A;  3SOV A;  2P16 L;  4XL1 A;  4A94 C;  1IP0 A;  2F9B L;  1CX2 A;  3F1S B;  1UZK A;  3HS5 A;  2RHP A;  1ATB A;  4Z6A L;  1TOZ A;  3SOB B;  2W2Q E;  2TGF A;  2BQ7 A;  2VVC K;  1MQ5 L;  2VWM K;  1G1Q A;  1TPG A;  1K37 A;  1PRH A;  1HX2 A;  1G2L B;  1UZJ A;  2BZ6 L;  1XKB A;  1C5M F;  2Y5F L;  1FF7 A;  1IGX A;  1EPH A;  2W2M E;  3LC3 B;  1IQH L;  1UZQ A;  1LMM A;  2OYE P;  2W86 A;  2GD4 A;  3KQE L;  1CCF A;  1FJS L;  3U7U G;  1YUK B;  4JZF L;  3GCW E;  4NGA L;  1LPG A;  2P3F N;  1NPE B;  2BOK L;  1Z6E L;  2Y5H L;  4Z0K B;  2P3F L;  1KLO A;  5L2Y L;  4M10 A;  4Z0L A;  5FDQ A;  3N8V A;  2P28 B;  1G2M B;  2D1J B;  1I0U A;  3NJP C;  1NFW B;  3IIT B;  2XBW L;  4BXS A;  3HO4 A;  2Q1J B;  2RA0 L;  1DX5 I;  2VJ3 A;  2J94 B;  1DDX A;  3LN0 A;  5IKQ A;  1F7E A;  1CVU A;  2MGP A;  4XLW A;  1KIG L;  1G1R A;  2P95 L;  3N8Y A;  1WHF A;  2WYJ B;  5COX A;  1HT5 A;  2FLB L;  2WG3 C;  1APQ A;  1G1S A;  1GK5 A;  1NFX B;  1P0S L;  2PR3 B;  1ZAQ A;  2EI6 B;  5E8D A;  3Q7D A;  1APO A;  5L30 L;  1RFN B;  3LAQ A;  1EBV A;  2XBX L;  3SW2 A;  2W26 B;  1HRF A;  1EQG A;  4MMY B;  4LOR A;  3BT1 A;  3CS7 L;  4A7I A;  2Y7Z B;  4O02 B;  2ADX A;  2Y7X B;  1EZQ B;  2Y80 B;  4LMF A;  2EI8 B;  4NG9 L;  1EAI C;  4Y79 B;  1IGZ A;  2RNL A;  2XC0 L;  1EGF A;  4D0F A;  3HS6 A;  4RS0 A;  1ATA A;  2K2S B;  1NT0 A;  4ZXX L;  4C16 A;  3RR3 A;  1YGC L;  2FLG A;  2J2U B;  1KLI L;  2W3K B;  5L2Z L;  1NQL B;  2NPR A;  4D0E A;  3K9X A;  1A3P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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