2P95L

Factor xa in complex with the inhibitor 5-chloro-n-((1r,2s)-2-(4-(2-oxopyridin-1(2h)-yl)benzamido) cyclopentyl)thiophene-2-carboxamide
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Factor Xa
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2p95L00
1FE2A 1FAXL 3NTGA 4RUTA 1CCVA 1LPZA 1HAFA 3CFWA 5JBBE 4MMZB 4XLWA 3CS7L 1CCFA 3LN0A 1FAKL 1NQLB 2OYUP 2I9AA 2VVVL 2PHBB 1IP0A 2G00L 2PR3B 1I0UA 4BDWA 2VVCK 3HS5A 1LMJA 1M1XB 5I46L 1FFMA 4Y7BB 2BZ6L 1APQA 1IQKL 2P94L 5L30L 1HRFA 2BQWA 2Y5HL 5CKNA 1UZKA 3ZYIB 3KQEL 1HJ7A 1URKA 1RFNB 4M10A 1EPGA 1KIGL 2AYLA 1FF7A 2Y7XB 1NPEB 1XDTR 1NFXB 2BQ6A 1N7DA 2K2TA 4Y76B 3QCWA 5E8DA 2J38B 2TGFA 3LTFB 3POYA 5JW1A 4PH9A 3PGHA 3SW2A 2NPRA 1CVUA 5CKMA 3QMOA 1IQGL 5F1AA 1FJSL 3H5CB 3EGFA 1XKAL 3BPSE 5L2ZL 1G2LB 1IQIL 2VJ3A 2FLBL 2XC0L 5CKQA 1KSNB 1A3PA 2WYGB 2XBVL 5FDQA 2W3IB 2WFXB 2J4IB 2K2SB 2WPKE 5IKRA 1DVAL 1FSBA 3BT2A 1L5GB 1EQGA 1JBUL 4E1GA 5K0HB 2WPLE 3GISX 1HX2A 3BT1A 3ELAL 1XKBA 3FCSB 2I9BA 1V3XB 1BF9A 2XC4L 1G2MB 2UWOB 2VH0B 4NG9L 3KQBL 3Q3KB 5JVZA 1EMOA 1HT8A 3TZIA 1LQDA 2W2ME 1IOXA 2KL7A 1IQML 5JB8E 1WHEA 2H9EL 4X8UL 3MDLA 1IVOC 1HAEA 2RA0L 3N8WA 3KL6B 3R05A 2P3UA 3LIWB 1APOA 3HPTA 1NT0A 2Y81B 2W2PE 1KLJL 3LC5B 4RRZA 1EQHA 2W3KB 4LMFA 4RRYA 5COXA 5IKQA 1OB1C 1PRHA 3KQCL 3KCGL 4NGAL 1DDXA 3F6UL 3HS7A 4Y7AB 3OLUA 2JKHL 2WG3C 1G1QA 1EPJA 5JB9E 2XBYL 4BTUA 3CENL 2BQ7A 1IQLL 2Y82B 4Z0KB 4BDXA 3GCXE 4D90A 3ZYJB 1XFEA 2Y7ZB 1U8CB 2ADXA 2PUQL 4RRWA 3U73A 3TH3L 1JL9A 1HZ8A 4JYUL 1NZIA 3N8YA 2P3FL 1PTHA 1EMNA 4ZH8B 2J94B 3KK6A 1G1RA 2W2NE 4JZFL 1CQEA 2FLRL 2WPHE 2VWOL 4BXSA 4C16A 1G1TA 1NFWB 2D1JB 1DQBA 4YZUB 2KV4A 3HO5A 1PGEA 1K36A 4JZDL 1YUGA 4Y71B 1ATBA 1LPGA 3TBDA 4ISHL 4Y79B 2Y38A 1WU1B 4A7IA 1HREA 4MMYB 2P16L 3CA7A 1ZAQA 3KQDL 1UZQA 2FZZL 1ATDA 1WHFA 3KRKA 3OLTA 4D0EA 2UWLB 1IJQA 2RHPA 3SOBB 1TOZA 1X7AL 1SZBA 2EI7B 1IGZA 3NT1A 1MQ5L 2J95B 2XC5L 2WFTA 5IKTA 2RNLA 1NFYB 4O02B 1AUTL 4YT7L 1O5DL 2W2OE 4G1MB 3LC3B 1F0RB 2BOUA 5KN5C 2P3TA 3FFGL 1KLOA 4OTJA 4CUFA 3NTBA 2WYJB 4JYVL 1CX2A 2BOHA 3LAQA 1EBVA 4Z6AL 3Q7DA 5CISA 3DEMA 2VWMK 2VH6B 6COXA 4CUEA 3NJPC 3N8XA 3V65B 1EGFA 4X8VL 2MGPA 2P3FN 1MOXC 2BMGA 3HO3A 1Z6EL 2B7DL 3M37L 2VVUL 1DIYA 4XBMA 4TGFA 4Y6DB 3RR3A 1Q4GA 3TK5B 1IQHL 3K9XA 4OTYA 2OYEP 1IQJL 2F9BL 2FD6A 4YT6L 2J34B 1CEJA 3TGFA 1IOEL 5JBCE 3F1SB 4CSYA 2XBXL 3N8WB 2GD4A 2J2UB 2XBWL 4X8TL 1F7EA 1C5MF 2P28B 1PFXL 2P95L 4LORA 4BXWA 1F7MA 1IGXA 1DX5I 2Q1JB 5JVYA 1L3YA 2CJIB 1TPGA 2Y5GL 3C9AC 4AQTA 2EI6B 1NFUB 2P93L 3ENSA 4RS0A 4Z0LA 1ADXA 4BTTA 4ZAEB 5JBAE 4D0FA 1JV2B 2P26A 4RRXA 1EPIA 2W26B 3QH0A 1IQFL 1UZJA 3U7UG 2YGPA 4JZEL 1F0SB 1CVWL 2YGOA 1N1IA 2Y80B 3N8ZA 3N8YB 2MGRA 3P5BL 2VWNL 1QFKL 2EI8B 1ATAA 4ZXXL 1W7XL 3V64C 1K37A 1EPHA 1PXXA 3SOVA 1EAIC 1HT5A 3IITB 3N8VA 1ATEA 2FLGA 1P9JA 4BTIA 4ZHAB 1YO8A 4X8SL 4CUDA 1COUA 1YUFA 2KB9A 1LPKA 5IKVA 4NA9L 2BOKL 2WPME 2MHPA 2W86A 1IQEL 2VWLL 1UZPA 4O1ZA 1J9CL 4ISIL 3ZYGA 3IJEB 4XL1A 3LTGD 1B9WA 1TLEA 2BOXA 2WPIE 1EZQB 2W2QE 3LN1A 3ASIA 4MMXB 1G1SA 3GCWE 1HCGB 4FM5A 1GK5A 2WG4B 1MQ6L 3M36L 2UWPB 4COXA 2M74A 2WPJE 4ZXYL 5EGMB 3HS6A 3MQEA 4M11A 1KLIL 2DDUA 3SOQA 3HO4A 1YGCL 5L2YL 1IQNL 5F19A 5KIRA 1YUKB 1P0SL 1W8BL 2Y5FL 1U67A 3TK6B 1Z6CA 3FBYA 2BO2A
chains in the Genus database with same CATH superfamily
1FE2A 1FAXL 3NTGA 4RUTA 1CCVA 1LPZA 1KKEA 1HAFA 3CFWA 5JBBE 4MMZB 4XLWA 3CS7L 1CCFA 3LN0A 1FAKL 1NQLB 2OYUP 2I9AA 2VVVL 2PHBB 1IP0A 2G00L 2PR3B 1I0UA 4BDWA 2VVCK 3HS5A 1LMJA 1M1XB 5I46L 1FFMA 4Y7BB 2BZ6L 1APQA 1IQKL 2P94L 5L30L 1HRFA 2BQWA 2Y5HL 5CKNA 1UZKA 3ZYIB 3KQEL 1HJ7A 1URKA 1RFNB 4M10A 1EPGA 1KIGL 2AYLA 1FF7A 2Y7XB 1NPEB 1XDTR 1NFXB 2BQ6A 1N7DA 2K2TA 4Y76B 3QCWA 5E8DA 2J38B 2TGFA 3LTFB 2BSFA 3POYA 5JW1A 4PH9A 3PGHA 3SW2A 2NPRA 1CVUA 5CKMA 3QMOA 1IQGL 5F1AA 1FJSL 3H5CB 3EGFA 1XKAL 3BPSE 1QIUA 5L2ZL 1G2LB 1IQIL 2VJ3A 2FLBL 2XC0L 5CKQA 1KSNB 1A3PA 2WZPP 2WYGB 2XBVL 5FDQA 2W3IB 2WFXB 2J4IB 2K2SB 2WPKE 5IKRA 1DVAL 1LMMA 1FSBA 3BT2A 1L5GB 1EQGA 2H9EC 1JBUL 4E1GA 5K0HB 2WPLE 3GISX 1V1HA 1HX2A 3BT1A 3ELAL 4GU4A 1XKBA 3FCSB 2I9BA 1V3XB 1BF9A 1LK9A 2XC4L 1G2MB 2UWOB 2VH0B 4NG9L 3KQBL 3Q3KB 5JVZA 1EMOA 1HT8A 3TZIA 1LQDA 2W2ME 1IOXA 2KL7A 1IQML 5JB8E 1WHEA 3S6XA 2H9EL 4X8UL 3MDLA 1IVOC 1HAEA 2RA0L 3N8WA 3KL6B 3R05A 2P3UA 3LIWB 1APOA 3HPTA 1NT0A 2Y81B 2W2PE 1KLJL 2JJLA 3LC5B 4RRZA 1EQHA 2W3KB 4LMFA 4RRYA 5COXA 5IKQA 1OB1C 1PRHA 3KQCL 3KCGL 4NGAL 1DDXA 3F6UL 3HS7A 4Y7AB 3OLUA 2JKHL 2WG3C 1G1QA 1EPJA 5JB9E 2XBYL 4BTUA 3CENL 2BQ7A 1IQLL 2Y82B 4Z0KB 4BDXA 3GCXE 4D90A 3ZYJB 1XFEA 2Y7ZB 1U8CB 2ADXA 2PUQL 4RRWA 3U73A 3TH3L 1JL9A 1HZ8A 4JYUL 1NZIA 3N8YA 2P3FL 1PTHA 1EMNA 4ZH8B 2J94B 3KK6A 1G1RA 2W2NE 4JZFL 1CQEA 2FLRL 2WPHE 2VWOL 4BXSA 4C16A 1G1TA 1NFWB 2D1JB 1DQBA 4YZUB 2KV4A 3HO5A 1V1IA 1PGEA 1K36A 4JZDL 1YUGA 4Y71B 1ATBA 1LPGA 3TBDA 4ISHL 4Y79B 2Y38A 1WU1B 4A7IA 1HREA 4MMYB 2P16L 3CA7A 1ZAQA 3KQDL 1UZQA 2FZZL 1ATDA 1WHFA 3KRKA 3OLTA 4D0EA 2VRSA 2UWLB 1IJQA 2YGQA 2RHPA 3SOBB 1TOZA 1X7AL 1SZBA 2EI7B 1IGZA 3NT1A 1MQ5L 2J95B 2XC5L 2WFTA 5IKTA 2RNLA 1NFYB 4O02B 1AUTL 4YT7L 1O5DL 2W2OE 4G1MB 3LC3B 1F0RB 2BOUA 5KN5C 2P3TA 3FFGL 1KLOA 4OTJA 4CUFA 3NTBA 2BT8A 2WYJB 4JYVL 1CX2A 2BOHA 3LAQA 1EBVA 4Z6AL 3Q7DA 5CISA 3DEMA 2VWMK 2VH6B 6COXA 4CUEA 2BT7A 3NJPC 3N8XA 3V65B 1EGFA 4X8VL 2MGPA 2P3FN 1MOXC 2HOXA 2BMGA 3HO3A 1Z6EL 2B7DL 3M37L 2VVUL 1DIYA 4XBMA 4TGFA 4Y6DB 3RR3A 1Q4GA 3TK5B 1IQHL 3K9XA 2KNIA 4OTYA 2OYEP 1IQJL 2F9BL 2FD6A 4YT6L 2J34B 1CEJA 3TGFA 1IOEL 5JBCE 3F1SB 4CSYA 2XBXL 3N8WB 2GD4A 2J2UB 2XBWL 4X8TL 1F7EA 1C5MF 2P28B 1PFXL 2P95L 4LORA 4BXWA 1F7MA 1IGXA 1DX5I 2Q1JB 5JVYA 1L3YA 2CJIB 1TPGA 2Y5GL 3C9AC 4AQTA 2EI6B 1NFUB 2P93L 3ENSA 4RS0A 4Z0LA 1ADXA 4BTTA 4ZAEB 5JBAE 4D0FA 1JV2B 2P26A 4RRXA 1EPIA 2W26B 3QH0A 1IQFL 1UZJA 3U7UG 2YGPA 2HORA 4JZEL 1F0SB 1CVWL 2YGOA 1N1IA 2Y80B 3N8ZA 3N8YB 2MGRA 3P5BL 2VWNL 1QFKL 2EI8B 1ATAA 4ZXXL 1W7XL 3V64C 1K37A 1EPHA 1PXXA 3SOVA 1EAIC 1HT5A 3IITB 3N8VA 1ATEA 2FLGA 1P9JA 4BTIA 4ZHAB 1YO8A 4X8SL 4CUDA 1COUA 1YUFA 2KB9A 1LPKA 5IKVA 4NA9L 2BOKL 2WPME 2MHPA 2W86A 1IQEL 2VWLL 1UZPA 4O1ZA 1J9CL 4ISIL 3ZYGA 3IJEB 4XL1A 3LTGD 1B9WA 1TLEA 2BOXA 2WPIE 1EZQB 2W2QE 3LN1A 4GU3A 3ASIA 4MMXB 1G1SA 3GCWE 1HCGB 4FM5A 1GK5A 2WG4B 1MQ6L 3M36L 2UWPB 4COXA 2M74A 2WPJE 4ZXYL 5EGMB 3HS6A 3MQEA 4M11A 1KLIL 2DDUA 3SOQA 3HO4A 1YGCL 5L2YL 1IQNL 5F19A 5KIRA 1YUKB 1P0SL 1W8BL 2Y5FL 1U67A 3TK6B 1Z6CA 4A94C 3FBYA 2BO2A
chains in the Genus database with same CATH topology
1FE2A 1FAXL 3NTGA 4RUTA 1CCVA 1LPZA 1HAFA 3CFWA 5JBBE 4MMZB 4XLWA 3CS7L 1CCFA 3LN0A 1FAKL 1NQLB 2OYUP 2I9AA 2VVVL 2PHBB 1IP0A 2G00L 2PR3B 1I0UA 4BDWA 2VVCK 3HS5A 1LMJA 1M1XB 5I46L 1FFMA 4Y7BB 2BZ6L 1APQA 1IQKL 2P94L 5L30L 1HRFA 2BQWA 2Y5HL 5CKNA 1UZKA 3ZYIB 3KQEL 1HJ7A 1URKA 1RFNB 4M10A 1EPGA 1KIGL 2AYLA 1FF7A 2Y7XB 1NPEB 1XDTR 1NFXB 2BQ6A 1N7DA 2K2TA 4Y76B 3QCWA 5E8DA 2J38B 2TGFA 3LTFB 3POYA 5JW1A 4PH9A 3PGHA 3SW2A 2NPRA 1CVUA 5CKMA 3QMOA 1IQGL 5F1AA 1FJSL 3H5CB 3EGFA 1XKAL 3BPSE 5L2ZL 1G2LB 1IQIL 2VJ3A 2FLBL 2XC0L 5CKQA 1KSNB 1A3PA 2WZPP 2WYGB 2XBVL 5FDQA 2W3IB 2WFXB 2J4IB 2K2SB 2WPKE 5IKRA 1DVAL 1LMMA 1FSBA 3BT2A 1L5GB 1EQGA 2H9EC 1JBUL 4E1GA 5K0HB 2WPLE 3GISX 1HX2A 3BT1A 3ELAL 1XKBA 3FCSB 2I9BA 1V3XB 1BF9A 2XC4L 1G2MB 2UWOB 2VH0B 4NG9L 3KQBL 3Q3KB 5JVZA 1EMOA 1HT8A 3TZIA 1LQDA 2W2ME 1IOXA 2KL7A 1IQML 5JB8E 1WHEA 3S6XA 2H9EL 4X8UL 3MDLA 1IVOC 1HAEA 2RA0L 3N8WA 3KL6B 3R05A 2P3UA 3LIWB 1APOA 3HPTA 1NT0A 2Y81B 2W2PE 1KLJL 3LC5B 4RRZA 1EQHA 2W3KB 4LMFA 4RRYA 5COXA 5IKQA 1OB1C 1PRHA 3KQCL 3KCGL 4NGAL 1DDXA 3F6UL 3HS7A 4Y7AB 3OLUA 2JKHL 2WG3C 1G1QA 1EPJA 5JB9E 2XBYL 4BTUA 3CENL 2BQ7A 1IQLL 2Y82B 4Z0KB 4BDXA 3GCXE 4D90A 3ZYJB 1XFEA 2Y7ZB 1U8CB 2ADXA 2PUQL 4RRWA 3U73A 3TH3L 1JL9A 1HZ8A 4JYUL 1NZIA 3N8YA 2P3FL 1PTHA 1EMNA 4ZH8B 2J94B 3KK6A 1G1RA 2W2NE 4JZFL 1CQEA 2FLRL 2WPHE 2VWOL 4BXSA 4C16A 1G1TA 1NFWB 2D1JB 1DQBA 4YZUB 2KV4A 3HO5A 1PGEA 1K36A 4JZDL 1YUGA 4Y71B 1ATBA 1LPGA 3TBDA 4ISHL 4Y79B 2Y38A 1WU1B 4A7IA 1HREA 4MMYB 2P16L 3CA7A 1ZAQA 3KQDL 1UZQA 2FZZL 1ATDA 1WHFA 3KRKA 3OLTA 4D0EA 2UWLB 1IJQA 2YGQA 2RHPA 3SOBB 1TOZA 1X7AL 1SZBA 2EI7B 1IGZA 3NT1A 1MQ5L 2J95B 2XC5L 2WFTA 5IKTA 2RNLA 1NFYB 4O02B 1AUTL 4YT7L 1O5DL 2W2OE 4G1MB 3LC3B 1F0RB 2BOUA 5KN5C 2P3TA 3FFGL 1KLOA 4OTJA 4CUFA 3NTBA 2WYJB 4JYVL 1CX2A 2BOHA 3LAQA 1EBVA 4Z6AL 3Q7DA 5CISA 3DEMA 2VWMK 2VH6B 6COXA 4CUEA 3NJPC 3N8XA 3V65B 1EGFA 4X8VL 2MGPA 2P3FN 1MOXC 2BMGA 3HO3A 1Z6EL 2B7DL 3M37L 2VVUL 1DIYA 4XBMA 4TGFA 4Y6DB 3RR3A 1Q4GA 3TK5B 1IQHL 3K9XA 2KNIA 4OTYA 2OYEP 1IQJL 2F9BL 2FD6A 4YT6L 2J34B 1CEJA 3TGFA 1IOEL 5JBCE 3F1SB 4CSYA 2XBXL 3N8WB 2GD4A 2J2UB 2XBWL 4X8TL 1F7EA 1C5MF 2P28B 1PFXL 2P95L 4LORA 4BXWA 1F7MA 1IGXA 1DX5I 2Q1JB 5JVYA 1L3YA 2CJIB 1TPGA 2Y5GL 3C9AC 4AQTA 2EI6B 1NFUB 2P93L 3ENSA 4RS0A 4Z0LA 1ADXA 4BTTA 4ZAEB 5JBAE 4D0FA 1JV2B 2P26A 4RRXA 1EPIA 2W26B 3QH0A 1IQFL 1UZJA 3U7UG 2YGPA 4JZEL 1F0SB 1CVWL 2YGOA 1N1IA 2Y80B 3N8ZA 3N8YB 2MGRA 3P5BL 2VWNL 1QFKL 2EI8B 1ATAA 4ZXXL 1W7XL 3V64C 1K37A 1EPHA 1PXXA 3SOVA 1EAIC 1HT5A 3IITB 3N8VA 1ATEA 2FLGA 1P9JA 4BTIA 4ZHAB 1YO8A 4X8SL 4CUDA 1COUA 1YUFA 2KB9A 1LPKA 5IKVA 4NA9L 2BOKL 2WPME 2MHPA 2W86A 1IQEL 2VWLL 1UZPA 4O1ZA 1J9CL 4ISIL 3ZYGA 3IJEB 4XL1A 3LTGD 1B9WA 1TLEA 2BOXA 2WPIE 1EZQB 2W2QE 3LN1A 3ASIA 4MMXB 1G1SA 3GCWE 1HCGB 4FM5A 1GK5A 2WG4B 1MQ6L 3M36L 2UWPB 4COXA 2M74A 2WPJE 4ZXYL 5EGMB 3HS6A 3MQEA 4M11A 1KLIL 2DDUA 3SOQA 3HO4A 1YGCL 5L2YL 1IQNL 5F19A 5KIRA 1YUKB 1P0SL 1W8BL 2Y5FL 1U67A 3TK6B 1Z6CA 4A94C 3FBYA 2BO2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FE2 A;  1FAX L;  3NTG A;  4RUT A;  1CCV A;  1LPZ A;  1HAF A;  3CFW A;  5JBB E;  4MMZ B;  4XLW A;  3CS7 L;  1CCF A;  3LN0 A;  1FAK L;  1NQL B;  2OYU P;  2I9A A;  2VVV L;  2PHB B;  1IP0 A;  2G00 L;  2PR3 B;  1I0U A;  4BDW A;  2VVC K;  3HS5 A;  1LMJ A;  1M1X B;  5I46 L;  1FFM A;  4Y7B B;  2BZ6 L;  1APQ A;  1IQK L;  2P94 L;  5L30 L;  1HRF A;  2BQW A;  2Y5H L;  5CKN A;  1UZK A;  3ZYI B;  3KQE L;  1HJ7 A;  1URK A;  1RFN B;  4M10 A;  1EPG A;  1KIG L;  2AYL A;  1FF7 A;  2Y7X B;  1NPE B;  1XDT R;  1NFX B;  2BQ6 A;  1N7D A;  2K2T A;  4Y76 B;  3QCW A;  5E8D A;  2J38 B;  2TGF A;  3LTF B;  3POY A;  5JW1 A;  4PH9 A;  3PGH A;  3SW2 A;  2NPR A;  1CVU A;  5CKM A;  3QMO A;  1IQG L;  5F1A A;  1FJS L;  3H5C B;  3EGF A;  1XKA L;  3BPS E;  5L2Z L;  1G2L B;  1IQI L;  2VJ3 A;  2FLB L;  2XC0 L;  5CKQ A;  1KSN B;  1A3P A;  2WYG B;  2XBV L;  5FDQ A;  2W3I B;  2WFX B;  2J4I B;  2K2S B;  2WPK E;  5IKR A;  1DVA L;  1FSB A;  3BT2 A;  1L5G B;  1EQG A;  1JBU L;  4E1G A;  5K0H B;  2WPL E;  3GIS X;  1HX2 A;  3BT1 A;  3ELA L;  1XKB A;  3FCS B;  2I9B A;  1V3X B;  1BF9 A;  2XC4 L;  1G2M B;  2UWO B;  2VH0 B;  4NG9 L;  3KQB L;  3Q3K B;  5JVZ A;  1EMO A;  1HT8 A;  3TZI A;  1LQD A;  2W2M E;  1IOX A;  2KL7 A;  1IQM L;  5JB8 E;  1WHE A;  2H9E L;  4X8U L;  3MDL A;  1IVO C;  1HAE A;  2RA0 L;  3N8W A;  3KL6 B;  3R05 A;  2P3U A;  3LIW B;  1APO A;  3HPT A;  1NT0 A;  2Y81 B;  2W2P E;  1KLJ L;  3LC5 B;  4RRZ A;  1EQH A;  2W3K B;  4LMF A;  4RRY A;  5COX A;  5IKQ A;  1OB1 C;  1PRH A;  3KQC L;  3KCG L;  4NGA L;  1DDX A;  3F6U L;  3HS7 A;  4Y7A B;  3OLU A;  2JKH L;  2WG3 C;  1G1Q A;  1EPJ A;  5JB9 E;  2XBY L;  4BTU A;  3CEN L;  2BQ7 A;  1IQL L;  2Y82 B;  4Z0K B;  4BDX A;  3GCX E;  4D90 A;  3ZYJ B;  1XFE A;  2Y7Z B;  1U8C B;  2ADX A;  2PUQ L;  4RRW A;  3U73 A;  3TH3 L;  1JL9 A;  1HZ8 A;  4JYU L;  1NZI A;  3N8Y A;  2P3F L;  1PTH A;  1EMN A;  4ZH8 B;  2J94 B;  3KK6 A;  1G1R A;  2W2N E;  4JZF L;  1CQE A;  2FLR L;  2WPH E;  2VWO L;  4BXS A;  4C16 A;  1G1T A;  1NFW B;  2D1J B;  1DQB A;  4YZU B;  2KV4 A;  3HO5 A;  1PGE A;  1K36 A;  4JZD L;  1YUG A;  4Y71 B;  1ATB A;  1LPG A;  3TBD A;  4ISH L;  4Y79 B;  2Y38 A;  1WU1 B;  4A7I A;  1HRE A;  4MMY B;  2P16 L;  3CA7 A;  1ZAQ A;  3KQD L;  1UZQ A;  2FZZ L;  1ATD A;  1WHF A;  3KRK A;  3OLT A;  4D0E A;  2UWL B;  1IJQ A;  2RHP A;  3SOB B;  1TOZ A;  1X7A L;  1SZB A;  2EI7 B;  1IGZ A;  3NT1 A;  1MQ5 L;  2J95 B;  2XC5 L;  2WFT A;  5IKT A;  2RNL A;  1NFY B;  4O02 B;  1AUT L;  4YT7 L;  1O5D L;  2W2O E;  4G1M B;  3LC3 B;  1F0R B;  2BOU A;  5KN5 C;  2P3T A;  3FFG L;  1KLO A;  4OTJ A;  4CUF A;  3NTB A;  2WYJ B;  4JYV L;  1CX2 A;  2BOH A;  3LAQ A;  1EBV A;  4Z6A L;  3Q7D A;  5CIS A;  3DEM A;  2VWM K;  2VH6 B;  6COX A;  4CUE A;  3NJP C;  3N8X A;  3V65 B;  1EGF A;  4X8V L;  2MGP A;  2P3F N;  1MOX C;  2BMG A;  3HO3 A;  1Z6E L;  2B7D L;  3M37 L;  2VVU L;  1DIY A;  4XBM A;  4TGF A;  4Y6D B;  3RR3 A;  1Q4G A;  3TK5 B;  1IQH L;  3K9X A;  4OTY A;  2OYE P;  1IQJ L;  2F9B L;  2FD6 A;  4YT6 L;  2J34 B;  1CEJ A;  3TGF A;  1IOE L;  5JBC E;  3F1S B;  4CSY A;  2XBX L;  3N8W B;  2GD4 A;  2J2U B;  2XBW L;  4X8T L;  1F7E A;  1C5M F;  2P28 B;  1PFX L;  2P95 L;  4LOR A;  4BXW A;  1F7M A;  1IGX A;  1DX5 I;  2Q1J B;  5JVY A;  1L3Y A;  2CJI B;  1TPG A;  2Y5G L;  3C9A C;  4AQT A;  2EI6 B;  1NFU B;  2P93 L;  3ENS A;  4RS0 A;  4Z0L A;  1ADX A;  4BTT A;  4ZAE B;  5JBA E;  4D0F A;  1JV2 B;  2P26 A;  4RRX A;  1EPI A;  2W26 B;  3QH0 A;  1IQF L;  1UZJ A;  3U7U G;  2YGP A;  4JZE L;  1F0S B;  1CVW L;  2YGO A;  1N1I A;  2Y80 B;  3N8Z A;  3N8Y B;  2MGR A;  3P5B L;  2VWN L;  1QFK L;  2EI8 B;  1ATA A;  4ZXX L;  1W7X L;  3V64 C;  1K37 A;  1EPH A;  1PXX A;  3SOV A;  1EAI C;  1HT5 A;  3IIT B;  3N8V A;  1ATE A;  2FLG A;  1P9J A;  4BTI A;  4ZHA B;  1YO8 A;  4X8S L;  4CUD A;  1COU A;  1YUF A;  2KB9 A;  1LPK A;  5IKV A;  4NA9 L;  2BOK L;  2WPM E;  2MHP A;  2W86 A;  1IQE L;  2VWL L;  1UZP A;  4O1Z A;  1J9C L;  4ISI L;  3ZYG A;  3IJE B;  4XL1 A;  3LTG D;  1B9W A;  1TLE A;  2BOX A;  2WPI E;  1EZQ B;  2W2Q E;  3LN1 A;  3ASI A;  4MMX B;  1G1S A;  3GCW E;  1HCG B;  4FM5 A;  1GK5 A;  2WG4 B;  1MQ6 L;  3M36 L;  2UWP B;  4COX A;  2M74 A;  2WPJ E;  4ZXY L;  5EGM B;  3HS6 A;  3MQE A;  4M11 A;  1KLI L;  2DDU A;  3SOQ A;  3HO4 A;  1YGC L;  5L2Y L;  1IQN L;  5F19 A;  5KIR A;  1YUK B;  1P0S L;  1W8B L;  2Y5F L;  1U67 A;  3TK6 B;  1Z6C A;  3FBY A;  2BO2 A; 
#chains in the Genus database with same CATH topology
 1FE2 A;  1FAX L;  3NTG A;  4RUT A;  1CCV A;  1LPZ A;  1KKE A;  1HAF A;  3CFW A;  5JBB E;  4MMZ B;  4XLW A;  3CS7 L;  1CCF A;  3LN0 A;  1FAK L;  1NQL B;  2OYU P;  2I9A A;  2VVV L;  2PHB B;  1IP0 A;  2G00 L;  2PR3 B;  1I0U A;  4BDW A;  2VVC K;  3HS5 A;  1LMJ A;  1M1X B;  5I46 L;  1FFM A;  4Y7B B;  2BZ6 L;  1APQ A;  1IQK L;  2P94 L;  5L30 L;  1HRF A;  2BQW A;  2Y5H L;  5CKN A;  1UZK A;  3ZYI B;  3KQE L;  1HJ7 A;  1URK A;  1RFN B;  4M10 A;  1EPG A;  1KIG L;  2AYL A;  1FF7 A;  2Y7X B;  1NPE B;  1XDT R;  1NFX B;  2BQ6 A;  1N7D A;  2K2T A;  4Y76 B;  3QCW A;  5E8D A;  2J38 B;  2TGF A;  3LTF B;  2BSF A;  3POY A;  5JW1 A;  4PH9 A;  3PGH A;  3SW2 A;  2NPR A;  1CVU A;  5CKM A;  3QMO A;  1IQG L;  5F1A A;  1FJS L;  3H5C B;  3EGF A;  1XKA L;  3BPS E;  1QIU A;  5L2Z L;  1G2L B;  1IQI L;  2VJ3 A;  2FLB L;  2XC0 L;  5CKQ A;  1KSN B;  1A3P A;  2WZP P;  2WYG B;  2XBV L;  5FDQ A;  2W3I B;  2WFX B;  2J4I B;  2K2S B;  2WPK E;  5IKR A;  1DVA L;  1LMM A;  1FSB A;  3BT2 A;  1L5G B;  1EQG A;  2H9E C;  1JBU L;  4E1G A;  5K0H B;  2WPL E;  3GIS X;  1V1H A;  1HX2 A;  3BT1 A;  3ELA L;  4GU4 A;  1XKB A;  3FCS B;  2I9B A;  1V3X B;  1BF9 A;  1LK9 A;  2XC4 L;  1G2M B;  2UWO B;  2VH0 B;  4NG9 L;  3KQB L;  3Q3K B;  5JVZ A;  1EMO A;  1HT8 A;  3TZI A;  1LQD A;  2W2M E;  1IOX A;  2KL7 A;  1IQM L;  5JB8 E;  1WHE A;  3S6X A;  2H9E L;  4X8U L;  3MDL A;  1IVO C;  1HAE A;  2RA0 L;  3N8W A;  3KL6 B;  3R05 A;  2P3U A;  3LIW B;  1APO A;  3HPT A;  1NT0 A;  2Y81 B;  2W2P E;  1KLJ L;  2JJL A;  3LC5 B;  4RRZ A;  1EQH A;  2W3K B;  4LMF A;  4RRY A;  5COX A;  5IKQ A;  1OB1 C;  1PRH A;  3KQC L;  3KCG L;  4NGA L;  1DDX A;  3F6U L;  3HS7 A;  4Y7A B;  3OLU A;  2JKH L;  2WG3 C;  1G1Q A;  1EPJ A;  5JB9 E;  2XBY L;  4BTU A;  3CEN L;  2BQ7 A;  1IQL L;  2Y82 B;  4Z0K B;  4BDX A;  3GCX E;  4D90 A;  3ZYJ B;  1XFE A;  2Y7Z B;  1U8C B;  2ADX A;  2PUQ L;  4RRW A;  3U73 A;  3TH3 L;  1JL9 A;  1HZ8 A;  4JYU L;  1NZI A;  3N8Y A;  2P3F L;  1PTH A;  1EMN A;  4ZH8 B;  2J94 B;  3KK6 A;  1G1R A;  2W2N E;  4JZF L;  1CQE A;  2FLR L;  2WPH E;  2VWO L;  4BXS A;  4C16 A;  1G1T A;  1NFW B;  2D1J B;  1DQB A;  4YZU B;  2KV4 A;  3HO5 A;  1V1I A;  1PGE A;  1K36 A;  4JZD L;  1YUG A;  4Y71 B;  1ATB A;  1LPG A;  3TBD A;  4ISH L;  4Y79 B;  2Y38 A;  1WU1 B;  4A7I A;  1HRE A;  4MMY B;  2P16 L;  3CA7 A;  1ZAQ A;  3KQD L;  1UZQ A;  2FZZ L;  1ATD A;  1WHF A;  3KRK A;  3OLT A;  4D0E A;  2VRS A;  2UWL B;  1IJQ A;  2YGQ A;  2RHP A;  3SOB B;  1TOZ A;  1X7A L;  1SZB A;  2EI7 B;  1IGZ A;  3NT1 A;  1MQ5 L;  2J95 B;  2XC5 L;  2WFT A;  5IKT A;  2RNL A;  1NFY B;  4O02 B;  1AUT L;  4YT7 L;  1O5D L;  2W2O E;  4G1M B;  3LC3 B;  1F0R B;  2BOU A;  5KN5 C;  2P3T A;  3FFG L;  1KLO A;  4OTJ A;  4CUF A;  3NTB A;  2BT8 A;  2WYJ B;  4JYV L;  1CX2 A;  2BOH A;  3LAQ A;  1EBV A;  4Z6A L;  3Q7D A;  5CIS A;  3DEM A;  2VWM K;  2VH6 B;  6COX A;  4CUE A;  2BT7 A;  3NJP C;  3N8X A;  3V65 B;  1EGF A;  4X8V L;  2MGP A;  2P3F N;  1MOX C;  2HOX A;  2BMG A;  3HO3 A;  1Z6E L;  2B7D L;  3M37 L;  2VVU L;  1DIY A;  4XBM A;  4TGF A;  4Y6D B;  3RR3 A;  1Q4G A;  3TK5 B;  1IQH L;  3K9X A;  2KNI A;  4OTY A;  2OYE P;  1IQJ L;  2F9B L;  2FD6 A;  4YT6 L;  2J34 B;  1CEJ A;  3TGF A;  1IOE L;  5JBC E;  3F1S B;  4CSY A;  2XBX L;  3N8W B;  2GD4 A;  2J2U B;  2XBW L;  4X8T L;  1F7E A;  1C5M F;  2P28 B;  1PFX L;  2P95 L;  4LOR A;  4BXW A;  1F7M A;  1IGX A;  1DX5 I;  2Q1J B;  5JVY A;  1L3Y A;  2CJI B;  1TPG A;  2Y5G L;  3C9A C;  4AQT A;  2EI6 B;  1NFU B;  2P93 L;  3ENS A;  4RS0 A;  4Z0L A;  1ADX A;  4BTT A;  4ZAE B;  5JBA E;  4D0F A;  1JV2 B;  2P26 A;  4RRX A;  1EPI A;  2W26 B;  3QH0 A;  1IQF L;  1UZJ A;  3U7U G;  2YGP A;  2HOR A;  4JZE L;  1F0S B;  1CVW L;  2YGO A;  1N1I A;  2Y80 B;  3N8Z A;  3N8Y B;  2MGR A;  3P5B L;  2VWN L;  1QFK L;  2EI8 B;  1ATA A;  4ZXX L;  1W7X L;  3V64 C;  1K37 A;  1EPH A;  1PXX A;  3SOV A;  1EAI C;  1HT5 A;  3IIT B;  3N8V A;  1ATE A;  2FLG A;  1P9J A;  4BTI A;  4ZHA B;  1YO8 A;  4X8S L;  4CUD A;  1COU A;  1YUF A;  2KB9 A;  1LPK A;  5IKV A;  4NA9 L;  2BOK L;  2WPM E;  2MHP A;  2W86 A;  1IQE L;  2VWL L;  1UZP A;  4O1Z A;  1J9C L;  4ISI L;  3ZYG A;  3IJE B;  4XL1 A;  3LTG D;  1B9W A;  1TLE A;  2BOX A;  2WPI E;  1EZQ B;  2W2Q E;  3LN1 A;  4GU3 A;  3ASI A;  4MMX B;  1G1S A;  3GCW E;  1HCG B;  4FM5 A;  1GK5 A;  2WG4 B;  1MQ6 L;  3M36 L;  2UWP B;  4COX A;  2M74 A;  2WPJ E;  4ZXY L;  5EGM B;  3HS6 A;  3MQE A;  4M11 A;  1KLI L;  2DDU A;  3SOQ A;  3HO4 A;  1YGC L;  5L2Y L;  1IQN L;  5F19 A;  5KIR A;  1YUK B;  1P0S L;  1W8B L;  2Y5F L;  1U67 A;  3TK6 B;  1Z6C A;  4A94 C;  3FBY A;  2BO2 A; 
#chains in the Genus database with same CATH homology
 1FE2 A;  1FAX L;  3NTG A;  4RUT A;  1CCV A;  1LPZ A;  1HAF A;  3CFW A;  5JBB E;  4MMZ B;  4XLW A;  3CS7 L;  1CCF A;  3LN0 A;  1FAK L;  1NQL B;  2OYU P;  2I9A A;  2VVV L;  2PHB B;  1IP0 A;  2G00 L;  2PR3 B;  1I0U A;  4BDW A;  2VVC K;  3HS5 A;  1LMJ A;  1M1X B;  5I46 L;  1FFM A;  4Y7B B;  2BZ6 L;  1APQ A;  1IQK L;  2P94 L;  5L30 L;  1HRF A;  2BQW A;  2Y5H L;  5CKN A;  1UZK A;  3ZYI B;  3KQE L;  1HJ7 A;  1URK A;  1RFN B;  4M10 A;  1EPG A;  1KIG L;  2AYL A;  1FF7 A;  2Y7X B;  1NPE B;  1XDT R;  1NFX B;  2BQ6 A;  1N7D A;  2K2T A;  4Y76 B;  3QCW A;  5E8D A;  2J38 B;  2TGF A;  3LTF B;  3POY A;  5JW1 A;  4PH9 A;  3PGH A;  3SW2 A;  2NPR A;  1CVU A;  5CKM A;  3QMO A;  1IQG L;  5F1A A;  1FJS L;  3H5C B;  3EGF A;  1XKA L;  3BPS E;  5L2Z L;  1G2L B;  1IQI L;  2VJ3 A;  2FLB L;  2XC0 L;  5CKQ A;  1KSN B;  1A3P A;  2WZP P;  2WYG B;  2XBV L;  5FDQ A;  2W3I B;  2WFX B;  2J4I B;  2K2S B;  2WPK E;  5IKR A;  1DVA L;  1LMM A;  1FSB A;  3BT2 A;  1L5G B;  1EQG A;  2H9E C;  1JBU L;  4E1G A;  5K0H B;  2WPL E;  3GIS X;  1HX2 A;  3BT1 A;  3ELA L;  1XKB A;  3FCS B;  2I9B A;  1V3X B;  1BF9 A;  2XC4 L;  1G2M B;  2UWO B;  2VH0 B;  4NG9 L;  3KQB L;  3Q3K B;  5JVZ A;  1EMO A;  1HT8 A;  3TZI A;  1LQD A;  2W2M E;  1IOX A;  2KL7 A;  1IQM L;  5JB8 E;  1WHE A;  3S6X A;  2H9E L;  4X8U L;  3MDL A;  1IVO C;  1HAE A;  2RA0 L;  3N8W A;  3KL6 B;  3R05 A;  2P3U A;  3LIW B;  1APO A;  3HPT A;  1NT0 A;  2Y81 B;  2W2P E;  1KLJ L;  3LC5 B;  4RRZ A;  1EQH A;  2W3K B;  4LMF A;  4RRY A;  5COX A;  5IKQ A;  1OB1 C;  1PRH A;  3KQC L;  3KCG L;  4NGA L;  1DDX A;  3F6U L;  3HS7 A;  4Y7A B;  3OLU A;  2JKH L;  2WG3 C;  1G1Q A;  1EPJ A;  5JB9 E;  2XBY L;  4BTU A;  3CEN L;  2BQ7 A;  1IQL L;  2Y82 B;  4Z0K B;  4BDX A;  3GCX E;  4D90 A;  3ZYJ B;  1XFE A;  2Y7Z B;  1U8C B;  2ADX A;  2PUQ L;  4RRW A;  3U73 A;  3TH3 L;  1JL9 A;  1HZ8 A;  4JYU L;  1NZI A;  3N8Y A;  2P3F L;  1PTH A;  1EMN A;  4ZH8 B;  2J94 B;  3KK6 A;  1G1R A;  2W2N E;  4JZF L;  1CQE A;  2FLR L;  2WPH E;  2VWO L;  4BXS A;  4C16 A;  1G1T A;  1NFW B;  2D1J B;  1DQB A;  4YZU B;  2KV4 A;  3HO5 A;  1PGE A;  1K36 A;  4JZD L;  1YUG A;  4Y71 B;  1ATB A;  1LPG A;  3TBD A;  4ISH L;  4Y79 B;  2Y38 A;  1WU1 B;  4A7I A;  1HRE A;  4MMY B;  2P16 L;  3CA7 A;  1ZAQ A;  3KQD L;  1UZQ A;  2FZZ L;  1ATD A;  1WHF A;  3KRK A;  3OLT A;  4D0E A;  2UWL B;  1IJQ A;  2YGQ A;  2RHP A;  3SOB B;  1TOZ A;  1X7A L;  1SZB A;  2EI7 B;  1IGZ A;  3NT1 A;  1MQ5 L;  2J95 B;  2XC5 L;  2WFT A;  5IKT A;  2RNL A;  1NFY B;  4O02 B;  1AUT L;  4YT7 L;  1O5D L;  2W2O E;  4G1M B;  3LC3 B;  1F0R B;  2BOU A;  5KN5 C;  2P3T A;  3FFG L;  1KLO A;  4OTJ A;  4CUF A;  3NTB A;  2WYJ B;  4JYV L;  1CX2 A;  2BOH A;  3LAQ A;  1EBV A;  4Z6A L;  3Q7D A;  5CIS A;  3DEM A;  2VWM K;  2VH6 B;  6COX A;  4CUE A;  3NJP C;  3N8X A;  3V65 B;  1EGF A;  4X8V L;  2MGP A;  2P3F N;  1MOX C;  2BMG A;  3HO3 A;  1Z6E L;  2B7D L;  3M37 L;  2VVU L;  1DIY A;  4XBM A;  4TGF A;  4Y6D B;  3RR3 A;  1Q4G A;  3TK5 B;  1IQH L;  3K9X A;  2KNI A;  4OTY A;  2OYE P;  1IQJ L;  2F9B L;  2FD6 A;  4YT6 L;  2J34 B;  1CEJ A;  3TGF A;  1IOE L;  5JBC E;  3F1S B;  4CSY A;  2XBX L;  3N8W B;  2GD4 A;  2J2U B;  2XBW L;  4X8T L;  1F7E A;  1C5M F;  2P28 B;  1PFX L;  2P95 L;  4LOR A;  4BXW A;  1F7M A;  1IGX A;  1DX5 I;  2Q1J B;  5JVY A;  1L3Y A;  2CJI B;  1TPG A;  2Y5G L;  3C9A C;  4AQT A;  2EI6 B;  1NFU B;  2P93 L;  3ENS A;  4RS0 A;  4Z0L A;  1ADX A;  4BTT A;  4ZAE B;  5JBA E;  4D0F A;  1JV2 B;  2P26 A;  4RRX A;  1EPI A;  2W26 B;  3QH0 A;  1IQF L;  1UZJ A;  3U7U G;  2YGP A;  4JZE L;  1F0S B;  1CVW L;  2YGO A;  1N1I A;  2Y80 B;  3N8Z A;  3N8Y B;  2MGR A;  3P5B L;  2VWN L;  1QFK L;  2EI8 B;  1ATA A;  4ZXX L;  1W7X L;  3V64 C;  1K37 A;  1EPH A;  1PXX A;  3SOV A;  1EAI C;  1HT5 A;  3IIT B;  3N8V A;  1ATE A;  2FLG A;  1P9J A;  4BTI A;  4ZHA B;  1YO8 A;  4X8S L;  4CUD A;  1COU A;  1YUF A;  2KB9 A;  1LPK A;  5IKV A;  4NA9 L;  2BOK L;  2WPM E;  2MHP A;  2W86 A;  1IQE L;  2VWL L;  1UZP A;  4O1Z A;  1J9C L;  4ISI L;  3ZYG A;  3IJE B;  4XL1 A;  3LTG D;  1B9W A;  1TLE A;  2BOX A;  2WPI E;  1EZQ B;  2W2Q E;  3LN1 A;  3ASI A;  4MMX B;  1G1S A;  3GCW E;  1HCG B;  4FM5 A;  1GK5 A;  2WG4 B;  1MQ6 L;  3M36 L;  2UWP B;  4COX A;  2M74 A;  2WPJ E;  4ZXY L;  5EGM B;  3HS6 A;  3MQE A;  4M11 A;  1KLI L;  2DDU A;  3SOQ A;  3HO4 A;  1YGC L;  5L2Y L;  1IQN L;  5F19 A;  5KIR A;  1YUK B;  1P0S L;  1W8B L;  2Y5F L;  1U67 A;  3TK6 B;  1Z6C A;  4A94 C;  3FBY A;  2BO2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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