2PR3B

Factor xa inhibitor
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
50
structure length
50
Chain Sequence
CSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitors
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords COAGULATION FACTOR X, HEAVY CHAIN
total genus 11
structure length 50
sequence length 50
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2pr3B00
4D90A 1G1TA 2WPJE 1NFWB 2FZZL 2VVUL 3HO4A 2G00L 1YUKB 1IOEL 3CENL 2BOXA 4NGAL 2P95L 1Q4GA 1IQHL 2J95B 2VH6B 3HS6A 2WFXB 1N7DA 3SOQA 4ZAEB 1G1SA 1K36A 4LORA 5E8DA 3NTGA 1F7MA 5FDQA 1WHFA 2UWLB 4OTJA 1GK5A 2WPME 4MMZB 2W2ME 2WPHE 3CS7L 1ATBA 5IKQA 3FCSB 4JZEL 3TK5B 2VVVL 1RFNB 5CKMA 5IKRA 4D0FA 2OYUP 2VWOL 4ZHAB 3N8WA 4E1GA 1FE2A 2PUQL 3RR3A 2FD6A 3OLTA 4PH9A 3GISX 2D1JB 4CUEA 1EPGA 1FAXL 4Y7AB 2H9EL 3MDLA 3CFWA 3KQEL 2RNLA 5EGMB 4X8TL 1FAKL 2BMGA 4C16A 3Q7DA 2XBYL 5L2ZL 5JBAE 2P16L 4XL1A 5IKVA 1U8CB 1HREA 2BOKL 2UWOB 2BO2A 3HPTA 4RRWA 5JBCE 3HO5A 4X8VL 4BXSA 4JYUL 1EAIC 2BQ7A 1FJSL 3N8XA 2Y5HL 2AYLA 3N8ZA 1PFXL 2W3KB 4COXA 1HZ8A 3N8YA 2EI7B 3BT1A 1UZJA 4CUDA 2YGOA 1NZIA 3KQDL 1BF9A 1X7AL 3IITB 2J38B 3R05A 4O02B 1IOXA 4Y76B 3KK6A 2W86A 5CISA 4Z0KB 1YUGA 1JL9A 1WHEA 2PHBB 4X8UL 1FSBA 5L30L 4JZFL 1YGCL 4XLWA 4RS0A 1ATAA 3K9XA 4NG9L 1Z6CA 4Y79B 1F7EA 1MQ5L 2CJIB 1LPZA 3IJEB 1XKBA 3TBDA 4X8SL 1WU1B 3U73A 1EPJA 4ISHL 1O5DL 4BXWA 1ADXA 1IJQA 4TGFA 1YO8A 1KLOA 1SZBA 2BOHA 3V64C 2VVCK 1J9CL 1OB1C 4G1MB 1CX2A 3ELAL 1TOZA 3FFGL 2EI8B 2KL7A 2VH0B 3TZIA 1EMOA 4Z6AL 1AUTL 4D0EA 2MGPA 3ENSA 4BDXA 1A3PA 2WPLE 1FFMA 2RHPA 2J34B 3NTBA 1APOA 1HT5A 2WFTA 1W8BL 1Z6EL 3KQBL 3LTGD 4CUFA 3EGFA 2P3TA 4ZH8B 1CCVA 2RA0L 2Y7ZB 2Y5FL 1HAEA 1UZPA 5K0HB 1U67A 4RRXA 3SOBB 1NQLB 2XBVL 1C5MF 4RUTA 1KIGL 5I46L 1IQJL 2J2UB 1JV2B 2MGRA 1HRFA 4YT6L 5L2YL 4RRYA 1G2MB 3NJPC 1UZQA 4JYVL 2XC4L 1IGZA 2BZ6L 3BT2A 3F6UL 2NPRA 1ATEA 2WG4B 2W2NE 5JB8E 3OLUA 5F19A 1ZAQA 3ASIA 2BQWA 3N8WB 1MQ6L 2VWNL 1DIYA 3QH0A 2Y7XB 1IQML 1KLIL 4M11A 2YGPA 3F1SB 1ATDA 2OYEP 3DEMA 2Y80B 3KQCL 3ZYGA 3LC5B 4ZXXL 3KRKA 1CQEA 4JZDL 5JBBE 1NT0A 2I9AA 3GCWE 2P3UA 1URKA 3Q3KB 3U7UG 1I0UA 2PR3B 2XBXL 4Y71B 5F1AA 1CCFA 1XFEA 5IKTA 1LPKA 1M1XB 2BQ6A 1PRHA 4O1ZA 3LTFB 2P26A 5JB9E 4NA9L 2WPIE 3TK6B 5KN5C 1DX5I 1FF7A 1HJ7A 3MQEA 2P3FN 3CA7A 5CKNA 1IQEL 1G1QA 2W2OE 1NPEB 5CKQA 2EI6B 3N8YB 5KIRA 2Y38A 1LPGA 1PTHA 3N8VA 4OTYA 2FLGA 1EPIA 4YT7L 2GD4A 1IGXA 1P0SL 1EBVA 2WG3C 6COXA 1HT8A 3QCWA 3SW2A 1HX2A 2P93L 1B9WA 2W3IB 3PGHA 1IQIL 3P5BL 3POYA 4AQTA 5JVZA 1DQBA 3SOVA 1IP0A 3ZYJB 4XBMA 2UWPB 2I9BA 1UZKA 4BTIA 2W2PE 4BDWA 2VWMK 1TLEA 3TGFA 2XBWL 1EMNA 2KV4A 2K2TA 1EQHA 3QMOA 1YUFA 2M74A 1LQDA 3LAQA 1IQGL 3HS7A 2WPKE 1KSNB 3LIWB 1KLJL 1NFXB 3BPSE 1APQA 2VJ3A 3GCXE 1XDTR 2ADXA 3M36L 5JW1A 1EPHA 3H5CB 2FLRL 4CSYA 2F9BL 1L3YA 3C9AC 3ZYIB 1JBUL 2B7DL 4A7IA 4Y7BB 4Y6DB 1IQLL 2W26B 1EZQB 2J4IB 2Y5GL 2J94B 1CEJA 1XKAL 2P94L 4Z0LA 2MHPA 1G2LB 1IQKL 2VWLL 1CVWL 4FM5A 3M37L 4ZXYL 1IQFL 2WYGB 5JVYA 1EGFA 3HS5A 3KCGL 2JKHL 3NT1A 1DVAL 1K37A 4RRZA 1EQGA 1V3XB 1P9JA 2XC0L 3HO3A 1TPGA 1PXXA 1COUA 2Y81B 3LC3B 1G1RA 1HCGB 2BOUA 2WYJB 3LN0A 3KL6B 4ISIL 1F0RB 1DDXA 2DDUA 2P28B 1CVUA 4BTUA 1LMJA 2KB9A 3FBYA 4YZUB 2Y82B 3LN1A 3V65B 4M10A 1IQNL 1IVOC 2Q1JB 4LMFA 1PGEA 5COXA 3TH3L 2P3FL 4MMXB 2W2QE 4MMYB 1N1IA 1QFKL 2K2SB 1W7XL 1F0SB 2XC5L 4BTTA 2FLBL 2TGFA 1HAFA 1NFYB 1NFUB 1L5GB 1MOXC
chains in the Genus database with same CATH superfamily
4D90A 1G1TA 2WPJE 1NFWB 2FZZL 1V1IA 2VVUL 3HO4A 2G00L 1YUKB 1IOEL 3CENL 2BOXA 4NGAL 2P95L 1Q4GA 1IQHL 2J95B 2VH6B 3HS6A 1V1HA 2WFXB 1N7DA 3SOQA 4ZAEB 1G1SA 1K36A 4LORA 5E8DA 3NTGA 1F7MA 2WZPP 5FDQA 1WHFA 2UWLB 4OTJA 1GK5A 2WPME 4MMZB 2W2ME 2WPHE 3CS7L 1ATBA 5IKQA 3FCSB 4JZEL 3TK5B 2VVVL 1RFNB 5CKMA 5IKRA 4D0FA 2OYUP 2VWOL 4ZHAB 3N8WA 4E1GA 1FE2A 2PUQL 3RR3A 2FD6A 3OLTA 4PH9A 3GISX 2D1JB 4CUEA 1EPGA 1FAXL 4Y7AB 2H9EL 3MDLA 3CFWA 3KQEL 2RNLA 5EGMB 3S6XA 4X8TL 1FAKL 2BMGA 4C16A 2KNIA 3Q7DA 2XBYL 5L2ZL 5JBAE 2P16L 4GU3A 4XL1A 5IKVA 1U8CB 1HREA 1LK9A 2BT7A 2BOKL 2UWOB 2BO2A 3HPTA 4RRWA 5JBCE 3HO5A 4X8VL 4BXSA 4JYUL 1EAIC 2BQ7A 1FJSL 3N8XA 2Y5HL 2AYLA 3N8ZA 1PFXL 1LMMA 2W3KB 4COXA 1HZ8A 3N8YA 2EI7B 3BT1A 1UZJA 4CUDA 2YGOA 1NZIA 3KQDL 1BF9A 1X7AL 3IITB 2J38B 3R05A 4O02B 1IOXA 4Y76B 3KK6A 2W86A 5CISA 4Z0KB 1YUGA 1JL9A 1WHEA 2PHBB 4X8UL 1FSBA 2BSFA 5L30L 4JZFL 1YGCL 4XLWA 4RS0A 1ATAA 3K9XA 4NG9L 1Z6CA 4Y79B 1F7EA 4A94C 1MQ5L 2CJIB 1LPZA 3IJEB 1XKBA 3TBDA 4X8SL 1WU1B 3U73A 1EPJA 4ISHL 1O5DL 4BXWA 1ADXA 1IJQA 4TGFA 1YO8A 1KLOA 1SZBA 2BOHA 3V64C 2VVCK 1J9CL 2VRSA 1OB1C 4G1MB 1CX2A 3ELAL 1TOZA 3FFGL 2EI8B 2KL7A 2VH0B 3TZIA 1EMOA 4Z6AL 1AUTL 4D0EA 2BT8A 2MGPA 3ENSA 4BDXA 1A3PA 2WPLE 1KKEA 1FFMA 2RHPA 2HORA 2J34B 3NTBA 1APOA 1HT5A 2WFTA 1W8BL 1Z6EL 3KQBL 3LTGD 4CUFA 3EGFA 2P3TA 4ZH8B 1CCVA 2RA0L 2Y7ZB 2Y5FL 1HAEA 1UZPA 5K0HB 1U67A 4RRXA 3SOBB 1NQLB 2XBVL 1C5MF 4RUTA 1KIGL 5I46L 1IQJL 2J2UB 1JV2B 2MGRA 1HRFA 4YT6L 5L2YL 4RRYA 1G2MB 3NJPC 1UZQA 4JYVL 2XC4L 1IGZA 2BZ6L 3BT2A 3F6UL 2NPRA 1ATEA 2WG4B 2W2NE 5JB8E 3OLUA 5F19A 1ZAQA 3ASIA 2BQWA 3N8WB 1MQ6L 2VWNL 1DIYA 3QH0A 2Y7XB 1IQML 1KLIL 4M11A 2YGPA 3F1SB 1ATDA 2OYEP 3DEMA 2Y80B 3KQCL 3ZYGA 3LC5B 4ZXXL 3KRKA 1CQEA 4JZDL 5JBBE 1NT0A 2I9AA 3GCWE 2P3UA 1URKA 3Q3KB 3U7UG 1I0UA 2PR3B 2XBXL 4Y71B 5F1AA 1CCFA 1XFEA 5IKTA 1LPKA 1M1XB 2BQ6A 1PRHA 4O1ZA 2H9EC 3LTFB 2P26A 5JB9E 4NA9L 2WPIE 3TK6B 5KN5C 1DX5I 1FF7A 1HJ7A 3MQEA 2P3FN 2HOXA 3CA7A 5CKNA 1IQEL 4GU4A 1G1QA 2W2OE 1NPEB 5CKQA 2EI6B 3N8YB 5KIRA 2Y38A 1LPGA 1PTHA 3N8VA 4OTYA 2FLGA 1EPIA 4YT7L 2GD4A 1IGXA 1P0SL 1EBVA 2WG3C 2YGQA 6COXA 1HT8A 3QCWA 3SW2A 1HX2A 2P93L 1B9WA 2W3IB 3PGHA 1IQIL 3P5BL 3POYA 4AQTA 5JVZA 1DQBA 3SOVA 1IP0A 3ZYJB 4XBMA 2UWPB 2I9BA 1UZKA 4BTIA 2W2PE 4BDWA 2VWMK 1TLEA 3TGFA 2XBWL 1EMNA 2KV4A 2K2TA 1EQHA 3QMOA 1YUFA 2M74A 1LQDA 3LAQA 1IQGL 3HS7A 2WPKE 1KSNB 3LIWB 1KLJL 1NFXB 3BPSE 1APQA 2VJ3A 3GCXE 1XDTR 2ADXA 3M36L 5JW1A 1EPHA 3H5CB 2FLRL 4CSYA 2F9BL 1L3YA 3C9AC 2JJLA 3ZYIB 1JBUL 2B7DL 4A7IA 4Y7BB 4Y6DB 1IQLL 2W26B 1EZQB 2J4IB 2Y5GL 2J94B 1QIUA 1CEJA 1XKAL 2P94L 4Z0LA 2MHPA 1G2LB 1IQKL 2VWLL 1CVWL 4FM5A 3M37L 4ZXYL 1IQFL 2WYGB 5JVYA 1EGFA 3HS5A 3KCGL 2JKHL 3NT1A 1DVAL 1K37A 4RRZA 1EQGA 1V3XB 1P9JA 2XC0L 3HO3A 1TPGA 1PXXA 1COUA 2Y81B 3LC3B 1G1RA 1HCGB 2BOUA 2WYJB 3LN0A 3KL6B 4ISIL 1F0RB 1DDXA 2DDUA 2P28B 1CVUA 4BTUA 1LMJA 2KB9A 3FBYA 4YZUB 2Y82B 3LN1A 3V65B 4M10A 1IQNL 1IVOC 2Q1JB 4LMFA 1PGEA 5COXA 3TH3L 2P3FL 4MMXB 2W2QE 4MMYB 1N1IA 1QFKL 2K2SB 1W7XL 1F0SB 2XC5L 4BTTA 2FLBL 2TGFA 1HAFA 1NFYB 1NFUB 1L5GB 1MOXC
chains in the Genus database with same CATH topology
4D90A 1G1TA 2WPJE 1NFWB 2FZZL 2VVUL 3HO4A 2G00L 1YUKB 1IOEL 3CENL 2BOXA 4NGAL 2P95L 1Q4GA 1IQHL 2J95B 2VH6B 3HS6A 2WFXB 1N7DA 3SOQA 4ZAEB 1G1SA 1K36A 4LORA 5E8DA 3NTGA 1F7MA 2WZPP 5FDQA 1WHFA 2UWLB 4OTJA 1GK5A 2WPME 4MMZB 2W2ME 2WPHE 3CS7L 1ATBA 5IKQA 3FCSB 4JZEL 3TK5B 2VVVL 1RFNB 5CKMA 5IKRA 4D0FA 2OYUP 2VWOL 4ZHAB 3N8WA 4E1GA 1FE2A 2PUQL 3RR3A 2FD6A 3OLTA 4PH9A 3GISX 2D1JB 4CUEA 1EPGA 1FAXL 4Y7AB 2H9EL 3MDLA 3CFWA 3KQEL 2RNLA 5EGMB 3S6XA 4X8TL 1FAKL 2BMGA 4C16A 2KNIA 3Q7DA 2XBYL 5L2ZL 5JBAE 2P16L 4XL1A 5IKVA 1U8CB 1HREA 2BOKL 2UWOB 2BO2A 3HPTA 4RRWA 5JBCE 3HO5A 4X8VL 4BXSA 4JYUL 1EAIC 2BQ7A 1FJSL 3N8XA 2Y5HL 2AYLA 3N8ZA 1PFXL 1LMMA 2W3KB 4COXA 1HZ8A 3N8YA 2EI7B 3BT1A 1UZJA 4CUDA 2YGOA 1NZIA 3KQDL 1BF9A 1X7AL 3IITB 2J38B 3R05A 4O02B 1IOXA 4Y76B 3KK6A 2W86A 5CISA 4Z0KB 1YUGA 1JL9A 1WHEA 2PHBB 4X8UL 1FSBA 5L30L 4JZFL 1YGCL 4XLWA 4RS0A 1ATAA 3K9XA 4NG9L 1Z6CA 4Y79B 1F7EA 4A94C 1MQ5L 2CJIB 1LPZA 3IJEB 1XKBA 3TBDA 4X8SL 1WU1B 3U73A 1EPJA 4ISHL 1O5DL 4BXWA 1ADXA 1IJQA 4TGFA 1YO8A 1KLOA 1SZBA 2BOHA 3V64C 2VVCK 1J9CL 1OB1C 4G1MB 1CX2A 3ELAL 1TOZA 3FFGL 2EI8B 2KL7A 2VH0B 3TZIA 1EMOA 4Z6AL 1AUTL 4D0EA 2MGPA 3ENSA 4BDXA 1A3PA 2WPLE 1FFMA 2RHPA 2J34B 3NTBA 1APOA 1HT5A 2WFTA 1W8BL 1Z6EL 3KQBL 3LTGD 4CUFA 3EGFA 2P3TA 4ZH8B 1CCVA 2RA0L 2Y7ZB 2Y5FL 1HAEA 1UZPA 5K0HB 1U67A 4RRXA 3SOBB 1NQLB 2XBVL 1C5MF 4RUTA 1KIGL 5I46L 1IQJL 2J2UB 1JV2B 2MGRA 1HRFA 4YT6L 5L2YL 4RRYA 1G2MB 3NJPC 1UZQA 4JYVL 2XC4L 1IGZA 2BZ6L 3BT2A 3F6UL 2NPRA 1ATEA 2WG4B 2W2NE 5JB8E 3OLUA 5F19A 1ZAQA 3ASIA 2BQWA 3N8WB 1MQ6L 2VWNL 1DIYA 3QH0A 2Y7XB 1IQML 1KLIL 4M11A 2YGPA 3F1SB 1ATDA 2OYEP 3DEMA 2Y80B 3KQCL 3ZYGA 3LC5B 4ZXXL 3KRKA 1CQEA 4JZDL 5JBBE 1NT0A 2I9AA 3GCWE 2P3UA 1URKA 3Q3KB 3U7UG 1I0UA 2PR3B 2XBXL 4Y71B 5F1AA 1CCFA 1XFEA 5IKTA 1LPKA 1M1XB 2BQ6A 1PRHA 4O1ZA 2H9EC 3LTFB 2P26A 5JB9E 4NA9L 2WPIE 3TK6B 5KN5C 1DX5I 1FF7A 1HJ7A 3MQEA 2P3FN 3CA7A 5CKNA 1IQEL 1G1QA 2W2OE 1NPEB 5CKQA 2EI6B 3N8YB 5KIRA 2Y38A 1LPGA 1PTHA 3N8VA 4OTYA 2FLGA 1EPIA 4YT7L 2GD4A 1IGXA 1P0SL 1EBVA 2WG3C 2YGQA 6COXA 1HT8A 3QCWA 3SW2A 1HX2A 2P93L 1B9WA 2W3IB 3PGHA 1IQIL 3P5BL 3POYA 4AQTA 5JVZA 1DQBA 3SOVA 1IP0A 3ZYJB 4XBMA 2UWPB 2I9BA 1UZKA 4BTIA 2W2PE 4BDWA 2VWMK 1TLEA 3TGFA 2XBWL 1EMNA 2KV4A 2K2TA 1EQHA 3QMOA 1YUFA 2M74A 1LQDA 3LAQA 1IQGL 3HS7A 2WPKE 1KSNB 3LIWB 1KLJL 1NFXB 3BPSE 1APQA 2VJ3A 3GCXE 1XDTR 2ADXA 3M36L 5JW1A 1EPHA 3H5CB 2FLRL 4CSYA 2F9BL 1L3YA 3C9AC 3ZYIB 1JBUL 2B7DL 4A7IA 4Y7BB 4Y6DB 1IQLL 2W26B 1EZQB 2J4IB 2Y5GL 2J94B 1CEJA 1XKAL 2P94L 4Z0LA 2MHPA 1G2LB 1IQKL 2VWLL 1CVWL 4FM5A 3M37L 4ZXYL 1IQFL 2WYGB 5JVYA 1EGFA 3HS5A 3KCGL 2JKHL 3NT1A 1DVAL 1K37A 4RRZA 1EQGA 1V3XB 1P9JA 2XC0L 3HO3A 1TPGA 1PXXA 1COUA 2Y81B 3LC3B 1G1RA 1HCGB 2BOUA 2WYJB 3LN0A 3KL6B 4ISIL 1F0RB 1DDXA 2DDUA 2P28B 1CVUA 4BTUA 1LMJA 2KB9A 3FBYA 4YZUB 2Y82B 3LN1A 3V65B 4M10A 1IQNL 1IVOC 2Q1JB 4LMFA 1PGEA 5COXA 3TH3L 2P3FL 4MMXB 2W2QE 4MMYB 1N1IA 1QFKL 2K2SB 1W7XL 1F0SB 2XC5L 4BTTA 2FLBL 2TGFA 1HAFA 1NFYB 1NFUB 1L5GB 1MOXC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D90 A;  1G1T A;  2WPJ E;  1NFW B;  2FZZ L;  2VVU L;  3HO4 A;  2G00 L;  1YUK B;  1IOE L;  3CEN L;  2BOX A;  4NGA L;  2P95 L;  1Q4G A;  1IQH L;  2J95 B;  2VH6 B;  3HS6 A;  2WFX B;  1N7D A;  3SOQ A;  4ZAE B;  1G1S A;  1K36 A;  4LOR A;  5E8D A;  3NTG A;  1F7M A;  5FDQ A;  1WHF A;  2UWL B;  4OTJ A;  1GK5 A;  2WPM E;  4MMZ B;  2W2M E;  2WPH E;  3CS7 L;  1ATB A;  5IKQ A;  3FCS B;  4JZE L;  3TK5 B;  2VVV L;  1RFN B;  5CKM A;  5IKR A;  4D0F A;  2OYU P;  2VWO L;  4ZHA B;  3N8W A;  4E1G A;  1FE2 A;  2PUQ L;  3RR3 A;  2FD6 A;  3OLT A;  4PH9 A;  3GIS X;  2D1J B;  4CUE A;  1EPG A;  1FAX L;  4Y7A B;  2H9E L;  3MDL A;  3CFW A;  3KQE L;  2RNL A;  5EGM B;  4X8T L;  1FAK L;  2BMG A;  4C16 A;  3Q7D A;  2XBY L;  5L2Z L;  5JBA E;  2P16 L;  4XL1 A;  5IKV A;  1U8C B;  1HRE A;  2BOK L;  2UWO B;  2BO2 A;  3HPT A;  4RRW A;  5JBC E;  3HO5 A;  4X8V L;  4BXS A;  4JYU L;  1EAI C;  2BQ7 A;  1FJS L;  3N8X A;  2Y5H L;  2AYL A;  3N8Z A;  1PFX L;  2W3K B;  4COX A;  1HZ8 A;  3N8Y A;  2EI7 B;  3BT1 A;  1UZJ A;  4CUD A;  2YGO A;  1NZI A;  3KQD L;  1BF9 A;  1X7A L;  3IIT B;  2J38 B;  3R05 A;  4O02 B;  1IOX A;  4Y76 B;  3KK6 A;  2W86 A;  5CIS A;  4Z0K B;  1YUG A;  1JL9 A;  1WHE A;  2PHB B;  4X8U L;  1FSB A;  5L30 L;  4JZF L;  1YGC L;  4XLW A;  4RS0 A;  1ATA A;  3K9X A;  4NG9 L;  1Z6C A;  4Y79 B;  1F7E A;  1MQ5 L;  2CJI B;  1LPZ A;  3IJE B;  1XKB A;  3TBD A;  4X8S L;  1WU1 B;  3U73 A;  1EPJ A;  4ISH L;  1O5D L;  4BXW A;  1ADX A;  1IJQ A;  4TGF A;  1YO8 A;  1KLO A;  1SZB A;  2BOH A;  3V64 C;  2VVC K;  1J9C L;  1OB1 C;  4G1M B;  1CX2 A;  3ELA L;  1TOZ A;  3FFG L;  2EI8 B;  2KL7 A;  2VH0 B;  3TZI A;  1EMO A;  4Z6A L;  1AUT L;  4D0E A;  2MGP A;  3ENS A;  4BDX A;  1A3P A;  2WPL E;  1FFM A;  2RHP A;  2J34 B;  3NTB A;  1APO A;  1HT5 A;  2WFT A;  1W8B L;  1Z6E L;  3KQB L;  3LTG D;  4CUF A;  3EGF A;  2P3T A;  4ZH8 B;  1CCV A;  2RA0 L;  2Y7Z B;  2Y5F L;  1HAE A;  1UZP A;  5K0H B;  1U67 A;  4RRX A;  3SOB B;  1NQL B;  2XBV L;  1C5M F;  4RUT A;  1KIG L;  5I46 L;  1IQJ L;  2J2U B;  1JV2 B;  2MGR A;  1HRF A;  4YT6 L;  5L2Y L;  4RRY A;  1G2M B;  3NJP C;  1UZQ A;  4JYV L;  2XC4 L;  1IGZ A;  2BZ6 L;  3BT2 A;  3F6U L;  2NPR A;  1ATE A;  2WG4 B;  2W2N E;  5JB8 E;  3OLU A;  5F19 A;  1ZAQ A;  3ASI A;  2BQW A;  3N8W B;  1MQ6 L;  2VWN L;  1DIY A;  3QH0 A;  2Y7X B;  1IQM L;  1KLI L;  4M11 A;  2YGP A;  3F1S B;  1ATD A;  2OYE P;  3DEM A;  2Y80 B;  3KQC L;  3ZYG A;  3LC5 B;  4ZXX L;  3KRK A;  1CQE A;  4JZD L;  5JBB E;  1NT0 A;  2I9A A;  3GCW E;  2P3U A;  1URK A;  3Q3K B;  3U7U G;  1I0U A;  2PR3 B;  2XBX L;  4Y71 B;  5F1A A;  1CCF A;  1XFE A;  5IKT A;  1LPK A;  1M1X B;  2BQ6 A;  1PRH A;  4O1Z A;  3LTF B;  2P26 A;  5JB9 E;  4NA9 L;  2WPI E;  3TK6 B;  5KN5 C;  1DX5 I;  1FF7 A;  1HJ7 A;  3MQE A;  2P3F N;  3CA7 A;  5CKN A;  1IQE L;  1G1Q A;  2W2O E;  1NPE B;  5CKQ A;  2EI6 B;  3N8Y B;  5KIR A;  2Y38 A;  1LPG A;  1PTH A;  3N8V A;  4OTY A;  2FLG A;  1EPI A;  4YT7 L;  2GD4 A;  1IGX A;  1P0S L;  1EBV A;  2WG3 C;  6COX A;  1HT8 A;  3QCW A;  3SW2 A;  1HX2 A;  2P93 L;  1B9W A;  2W3I B;  3PGH A;  1IQI L;  3P5B L;  3POY A;  4AQT A;  5JVZ A;  1DQB A;  3SOV A;  1IP0 A;  3ZYJ B;  4XBM A;  2UWP B;  2I9B A;  1UZK A;  4BTI A;  2W2P E;  4BDW A;  2VWM K;  1TLE A;  3TGF A;  2XBW L;  1EMN A;  2KV4 A;  2K2T A;  1EQH A;  3QMO A;  1YUF A;  2M74 A;  1LQD A;  3LAQ A;  1IQG L;  3HS7 A;  2WPK E;  1KSN B;  3LIW B;  1KLJ L;  1NFX B;  3BPS E;  1APQ A;  2VJ3 A;  3GCX E;  1XDT R;  2ADX A;  3M36 L;  5JW1 A;  1EPH A;  3H5C B;  2FLR L;  4CSY A;  2F9B L;  1L3Y A;  3C9A C;  3ZYI B;  1JBU L;  2B7D L;  4A7I A;  4Y7B B;  4Y6D B;  1IQL L;  2W26 B;  1EZQ B;  2J4I B;  2Y5G L;  2J94 B;  1CEJ A;  1XKA L;  2P94 L;  4Z0L A;  2MHP A;  1G2L B;  1IQK L;  2VWL L;  1CVW L;  4FM5 A;  3M37 L;  4ZXY L;  1IQF L;  2WYG B;  5JVY A;  1EGF A;  3HS5 A;  3KCG L;  2JKH L;  3NT1 A;  1DVA L;  1K37 A;  4RRZ A;  1EQG A;  1V3X B;  1P9J A;  2XC0 L;  3HO3 A;  1TPG A;  1PXX A;  1COU A;  2Y81 B;  3LC3 B;  1G1R A;  1HCG B;  2BOU A;  2WYJ B;  3LN0 A;  3KL6 B;  4ISI L;  1F0R B;  1DDX A;  2DDU A;  2P28 B;  1CVU A;  4BTU A;  1LMJ A;  2KB9 A;  3FBY A;  4YZU B;  2Y82 B;  3LN1 A;  3V65 B;  4M10 A;  1IQN L;  1IVO C;  2Q1J B;  4LMF A;  1PGE A;  5COX A;  3TH3 L;  2P3F L;  4MMX B;  2W2Q E;  4MMY B;  1N1I A;  1QFK L;  2K2S B;  1W7X L;  1F0S B;  2XC5 L;  4BTT A;  2FLB L;  2TGF A;  1HAF A;  1NFY B;  1NFU B;  1L5G B;  1MOX C; 
#chains in the Genus database with same CATH topology
 4D90 A;  1G1T A;  2WPJ E;  1NFW B;  2FZZ L;  1V1I A;  2VVU L;  3HO4 A;  2G00 L;  1YUK B;  1IOE L;  3CEN L;  2BOX A;  4NGA L;  2P95 L;  1Q4G A;  1IQH L;  2J95 B;  2VH6 B;  3HS6 A;  1V1H A;  2WFX B;  1N7D A;  3SOQ A;  4ZAE B;  1G1S A;  1K36 A;  4LOR A;  5E8D A;  3NTG A;  1F7M A;  2WZP P;  5FDQ A;  1WHF A;  2UWL B;  4OTJ A;  1GK5 A;  2WPM E;  4MMZ B;  2W2M E;  2WPH E;  3CS7 L;  1ATB A;  5IKQ A;  3FCS B;  4JZE L;  3TK5 B;  2VVV L;  1RFN B;  5CKM A;  5IKR A;  4D0F A;  2OYU P;  2VWO L;  4ZHA B;  3N8W A;  4E1G A;  1FE2 A;  2PUQ L;  3RR3 A;  2FD6 A;  3OLT A;  4PH9 A;  3GIS X;  2D1J B;  4CUE A;  1EPG A;  1FAX L;  4Y7A B;  2H9E L;  3MDL A;  3CFW A;  3KQE L;  2RNL A;  5EGM B;  3S6X A;  4X8T L;  1FAK L;  2BMG A;  4C16 A;  2KNI A;  3Q7D A;  2XBY L;  5L2Z L;  5JBA E;  2P16 L;  4GU3 A;  4XL1 A;  5IKV A;  1U8C B;  1HRE A;  1LK9 A;  2BT7 A;  2BOK L;  2UWO B;  2BO2 A;  3HPT A;  4RRW A;  5JBC E;  3HO5 A;  4X8V L;  4BXS A;  4JYU L;  1EAI C;  2BQ7 A;  1FJS L;  3N8X A;  2Y5H L;  2AYL A;  3N8Z A;  1PFX L;  1LMM A;  2W3K B;  4COX A;  1HZ8 A;  3N8Y A;  2EI7 B;  3BT1 A;  1UZJ A;  4CUD A;  2YGO A;  1NZI A;  3KQD L;  1BF9 A;  1X7A L;  3IIT B;  2J38 B;  3R05 A;  4O02 B;  1IOX A;  4Y76 B;  3KK6 A;  2W86 A;  5CIS A;  4Z0K B;  1YUG A;  1JL9 A;  1WHE A;  2PHB B;  4X8U L;  1FSB A;  2BSF A;  5L30 L;  4JZF L;  1YGC L;  4XLW A;  4RS0 A;  1ATA A;  3K9X A;  4NG9 L;  1Z6C A;  4Y79 B;  1F7E A;  4A94 C;  1MQ5 L;  2CJI B;  1LPZ A;  3IJE B;  1XKB A;  3TBD A;  4X8S L;  1WU1 B;  3U73 A;  1EPJ A;  4ISH L;  1O5D L;  4BXW A;  1ADX A;  1IJQ A;  4TGF A;  1YO8 A;  1KLO A;  1SZB A;  2BOH A;  3V64 C;  2VVC K;  1J9C L;  2VRS A;  1OB1 C;  4G1M B;  1CX2 A;  3ELA L;  1TOZ A;  3FFG L;  2EI8 B;  2KL7 A;  2VH0 B;  3TZI A;  1EMO A;  4Z6A L;  1AUT L;  4D0E A;  2BT8 A;  2MGP A;  3ENS A;  4BDX A;  1A3P A;  2WPL E;  1KKE A;  1FFM A;  2RHP A;  2HOR A;  2J34 B;  3NTB A;  1APO A;  1HT5 A;  2WFT A;  1W8B L;  1Z6E L;  3KQB L;  3LTG D;  4CUF A;  3EGF A;  2P3T A;  4ZH8 B;  1CCV A;  2RA0 L;  2Y7Z B;  2Y5F L;  1HAE A;  1UZP A;  5K0H B;  1U67 A;  4RRX A;  3SOB B;  1NQL B;  2XBV L;  1C5M F;  4RUT A;  1KIG L;  5I46 L;  1IQJ L;  2J2U B;  1JV2 B;  2MGR A;  1HRF A;  4YT6 L;  5L2Y L;  4RRY A;  1G2M B;  3NJP C;  1UZQ A;  4JYV L;  2XC4 L;  1IGZ A;  2BZ6 L;  3BT2 A;  3F6U L;  2NPR A;  1ATE A;  2WG4 B;  2W2N E;  5JB8 E;  3OLU A;  5F19 A;  1ZAQ A;  3ASI A;  2BQW A;  3N8W B;  1MQ6 L;  2VWN L;  1DIY A;  3QH0 A;  2Y7X B;  1IQM L;  1KLI L;  4M11 A;  2YGP A;  3F1S B;  1ATD A;  2OYE P;  3DEM A;  2Y80 B;  3KQC L;  3ZYG A;  3LC5 B;  4ZXX L;  3KRK A;  1CQE A;  4JZD L;  5JBB E;  1NT0 A;  2I9A A;  3GCW E;  2P3U A;  1URK A;  3Q3K B;  3U7U G;  1I0U A;  2PR3 B;  2XBX L;  4Y71 B;  5F1A A;  1CCF A;  1XFE A;  5IKT A;  1LPK A;  1M1X B;  2BQ6 A;  1PRH A;  4O1Z A;  2H9E C;  3LTF B;  2P26 A;  5JB9 E;  4NA9 L;  2WPI E;  3TK6 B;  5KN5 C;  1DX5 I;  1FF7 A;  1HJ7 A;  3MQE A;  2P3F N;  2HOX A;  3CA7 A;  5CKN A;  1IQE L;  4GU4 A;  1G1Q A;  2W2O E;  1NPE B;  5CKQ A;  2EI6 B;  3N8Y B;  5KIR A;  2Y38 A;  1LPG A;  1PTH A;  3N8V A;  4OTY A;  2FLG A;  1EPI A;  4YT7 L;  2GD4 A;  1IGX A;  1P0S L;  1EBV A;  2WG3 C;  2YGQ A;  6COX A;  1HT8 A;  3QCW A;  3SW2 A;  1HX2 A;  2P93 L;  1B9W A;  2W3I B;  3PGH A;  1IQI L;  3P5B L;  3POY A;  4AQT A;  5JVZ A;  1DQB A;  3SOV A;  1IP0 A;  3ZYJ B;  4XBM A;  2UWP B;  2I9B A;  1UZK A;  4BTI A;  2W2P E;  4BDW A;  2VWM K;  1TLE A;  3TGF A;  2XBW L;  1EMN A;  2KV4 A;  2K2T A;  1EQH A;  3QMO A;  1YUF A;  2M74 A;  1LQD A;  3LAQ A;  1IQG L;  3HS7 A;  2WPK E;  1KSN B;  3LIW B;  1KLJ L;  1NFX B;  3BPS E;  1APQ A;  2VJ3 A;  3GCX E;  1XDT R;  2ADX A;  3M36 L;  5JW1 A;  1EPH A;  3H5C B;  2FLR L;  4CSY A;  2F9B L;  1L3Y A;  3C9A C;  2JJL A;  3ZYI B;  1JBU L;  2B7D L;  4A7I A;  4Y7B B;  4Y6D B;  1IQL L;  2W26 B;  1EZQ B;  2J4I B;  2Y5G L;  2J94 B;  1QIU A;  1CEJ A;  1XKA L;  2P94 L;  4Z0L A;  2MHP A;  1G2L B;  1IQK L;  2VWL L;  1CVW L;  4FM5 A;  3M37 L;  4ZXY L;  1IQF L;  2WYG B;  5JVY A;  1EGF A;  3HS5 A;  3KCG L;  2JKH L;  3NT1 A;  1DVA L;  1K37 A;  4RRZ A;  1EQG A;  1V3X B;  1P9J A;  2XC0 L;  3HO3 A;  1TPG A;  1PXX A;  1COU A;  2Y81 B;  3LC3 B;  1G1R A;  1HCG B;  2BOU A;  2WYJ B;  3LN0 A;  3KL6 B;  4ISI L;  1F0R B;  1DDX A;  2DDU A;  2P28 B;  1CVU A;  4BTU A;  1LMJ A;  2KB9 A;  3FBY A;  4YZU B;  2Y82 B;  3LN1 A;  3V65 B;  4M10 A;  1IQN L;  1IVO C;  2Q1J B;  4LMF A;  1PGE A;  5COX A;  3TH3 L;  2P3F L;  4MMX B;  2W2Q E;  4MMY B;  1N1I A;  1QFK L;  2K2S B;  1W7X L;  1F0S B;  2XC5 L;  4BTT A;  2FLB L;  2TGF A;  1HAF A;  1NFY B;  1NFU B;  1L5G B;  1MOX C; 
#chains in the Genus database with same CATH homology
 4D90 A;  1G1T A;  2WPJ E;  1NFW B;  2FZZ L;  2VVU L;  3HO4 A;  2G00 L;  1YUK B;  1IOE L;  3CEN L;  2BOX A;  4NGA L;  2P95 L;  1Q4G A;  1IQH L;  2J95 B;  2VH6 B;  3HS6 A;  2WFX B;  1N7D A;  3SOQ A;  4ZAE B;  1G1S A;  1K36 A;  4LOR A;  5E8D A;  3NTG A;  1F7M A;  2WZP P;  5FDQ A;  1WHF A;  2UWL B;  4OTJ A;  1GK5 A;  2WPM E;  4MMZ B;  2W2M E;  2WPH E;  3CS7 L;  1ATB A;  5IKQ A;  3FCS B;  4JZE L;  3TK5 B;  2VVV L;  1RFN B;  5CKM A;  5IKR A;  4D0F A;  2OYU P;  2VWO L;  4ZHA B;  3N8W A;  4E1G A;  1FE2 A;  2PUQ L;  3RR3 A;  2FD6 A;  3OLT A;  4PH9 A;  3GIS X;  2D1J B;  4CUE A;  1EPG A;  1FAX L;  4Y7A B;  2H9E L;  3MDL A;  3CFW A;  3KQE L;  2RNL A;  5EGM B;  3S6X A;  4X8T L;  1FAK L;  2BMG A;  4C16 A;  2KNI A;  3Q7D A;  2XBY L;  5L2Z L;  5JBA E;  2P16 L;  4XL1 A;  5IKV A;  1U8C B;  1HRE A;  2BOK L;  2UWO B;  2BO2 A;  3HPT A;  4RRW A;  5JBC E;  3HO5 A;  4X8V L;  4BXS A;  4JYU L;  1EAI C;  2BQ7 A;  1FJS L;  3N8X A;  2Y5H L;  2AYL A;  3N8Z A;  1PFX L;  1LMM A;  2W3K B;  4COX A;  1HZ8 A;  3N8Y A;  2EI7 B;  3BT1 A;  1UZJ A;  4CUD A;  2YGO A;  1NZI A;  3KQD L;  1BF9 A;  1X7A L;  3IIT B;  2J38 B;  3R05 A;  4O02 B;  1IOX A;  4Y76 B;  3KK6 A;  2W86 A;  5CIS A;  4Z0K B;  1YUG A;  1JL9 A;  1WHE A;  2PHB B;  4X8U L;  1FSB A;  5L30 L;  4JZF L;  1YGC L;  4XLW A;  4RS0 A;  1ATA A;  3K9X A;  4NG9 L;  1Z6C A;  4Y79 B;  1F7E A;  4A94 C;  1MQ5 L;  2CJI B;  1LPZ A;  3IJE B;  1XKB A;  3TBD A;  4X8S L;  1WU1 B;  3U73 A;  1EPJ A;  4ISH L;  1O5D L;  4BXW A;  1ADX A;  1IJQ A;  4TGF A;  1YO8 A;  1KLO A;  1SZB A;  2BOH A;  3V64 C;  2VVC K;  1J9C L;  1OB1 C;  4G1M B;  1CX2 A;  3ELA L;  1TOZ A;  3FFG L;  2EI8 B;  2KL7 A;  2VH0 B;  3TZI A;  1EMO A;  4Z6A L;  1AUT L;  4D0E A;  2MGP A;  3ENS A;  4BDX A;  1A3P A;  2WPL E;  1FFM A;  2RHP A;  2J34 B;  3NTB A;  1APO A;  1HT5 A;  2WFT A;  1W8B L;  1Z6E L;  3KQB L;  3LTG D;  4CUF A;  3EGF A;  2P3T A;  4ZH8 B;  1CCV A;  2RA0 L;  2Y7Z B;  2Y5F L;  1HAE A;  1UZP A;  5K0H B;  1U67 A;  4RRX A;  3SOB B;  1NQL B;  2XBV L;  1C5M F;  4RUT A;  1KIG L;  5I46 L;  1IQJ L;  2J2U B;  1JV2 B;  2MGR A;  1HRF A;  4YT6 L;  5L2Y L;  4RRY A;  1G2M B;  3NJP C;  1UZQ A;  4JYV L;  2XC4 L;  1IGZ A;  2BZ6 L;  3BT2 A;  3F6U L;  2NPR A;  1ATE A;  2WG4 B;  2W2N E;  5JB8 E;  3OLU A;  5F19 A;  1ZAQ A;  3ASI A;  2BQW A;  3N8W B;  1MQ6 L;  2VWN L;  1DIY A;  3QH0 A;  2Y7X B;  1IQM L;  1KLI L;  4M11 A;  2YGP A;  3F1S B;  1ATD A;  2OYE P;  3DEM A;  2Y80 B;  3KQC L;  3ZYG A;  3LC5 B;  4ZXX L;  3KRK A;  1CQE A;  4JZD L;  5JBB E;  1NT0 A;  2I9A A;  3GCW E;  2P3U A;  1URK A;  3Q3K B;  3U7U G;  1I0U A;  2PR3 B;  2XBX L;  4Y71 B;  5F1A A;  1CCF A;  1XFE A;  5IKT A;  1LPK A;  1M1X B;  2BQ6 A;  1PRH A;  4O1Z A;  2H9E C;  3LTF B;  2P26 A;  5JB9 E;  4NA9 L;  2WPI E;  3TK6 B;  5KN5 C;  1DX5 I;  1FF7 A;  1HJ7 A;  3MQE A;  2P3F N;  3CA7 A;  5CKN A;  1IQE L;  1G1Q A;  2W2O E;  1NPE B;  5CKQ A;  2EI6 B;  3N8Y B;  5KIR A;  2Y38 A;  1LPG A;  1PTH A;  3N8V A;  4OTY A;  2FLG A;  1EPI A;  4YT7 L;  2GD4 A;  1IGX A;  1P0S L;  1EBV A;  2WG3 C;  2YGQ A;  6COX A;  1HT8 A;  3QCW A;  3SW2 A;  1HX2 A;  2P93 L;  1B9W A;  2W3I B;  3PGH A;  1IQI L;  3P5B L;  3POY A;  4AQT A;  5JVZ A;  1DQB A;  3SOV A;  1IP0 A;  3ZYJ B;  4XBM A;  2UWP B;  2I9B A;  1UZK A;  4BTI A;  2W2P E;  4BDW A;  2VWM K;  1TLE A;  3TGF A;  2XBW L;  1EMN A;  2KV4 A;  2K2T A;  1EQH A;  3QMO A;  1YUF A;  2M74 A;  1LQD A;  3LAQ A;  1IQG L;  3HS7 A;  2WPK E;  1KSN B;  3LIW B;  1KLJ L;  1NFX B;  3BPS E;  1APQ A;  2VJ3 A;  3GCX E;  1XDT R;  2ADX A;  3M36 L;  5JW1 A;  1EPH A;  3H5C B;  2FLR L;  4CSY A;  2F9B L;  1L3Y A;  3C9A C;  3ZYI B;  1JBU L;  2B7D L;  4A7I A;  4Y7B B;  4Y6D B;  1IQL L;  2W26 B;  1EZQ B;  2J4I B;  2Y5G L;  2J94 B;  1CEJ A;  1XKA L;  2P94 L;  4Z0L A;  2MHP A;  1G2L B;  1IQK L;  2VWL L;  1CVW L;  4FM5 A;  3M37 L;  4ZXY L;  1IQF L;  2WYG B;  5JVY A;  1EGF A;  3HS5 A;  3KCG L;  2JKH L;  3NT1 A;  1DVA L;  1K37 A;  4RRZ A;  1EQG A;  1V3X B;  1P9J A;  2XC0 L;  3HO3 A;  1TPG A;  1PXX A;  1COU A;  2Y81 B;  3LC3 B;  1G1R A;  1HCG B;  2BOU A;  2WYJ B;  3LN0 A;  3KL6 B;  4ISI L;  1F0R B;  1DDX A;  2DDU A;  2P28 B;  1CVU A;  4BTU A;  1LMJ A;  2KB9 A;  3FBY A;  4YZU B;  2Y82 B;  3LN1 A;  3V65 B;  4M10 A;  1IQN L;  1IVO C;  2Q1J B;  4LMF A;  1PGE A;  5COX A;  3TH3 L;  2P3F L;  4MMX B;  2W2Q E;  4MMY B;  1N1I A;  1QFK L;  2K2S B;  1W7X L;  1F0S B;  2XC5 L;  4BTT A;  2FLB L;  2TGF A;  1HAF A;  1NFY B;  1NFU B;  1L5G B;  1MOX C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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