2Q1JB

The discovery of glycine and related amino acid-based factor xa inhibitors
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
51
structure length
51
Chain Sequence
LCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Discovery of Glycine and Related Amino Acid-Based Factor Xa Inhibitors
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Activated factor Xa heavy chain (EC 3.4.21.6)
total genus 12
structure length 51
sequence length 51
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2q1jB00
1PFXL 1DDXA 1EBVA 5JBBE 1CVUA 1DIYA 1PGEA 1YGCL 4NA9L 2VJ3A 1GK5A 2WPLE 2PUQL 1EGFA 1NT0A 5E8DA 1M1XB 2TGFA 4CSYA 3N8WA 2P26A 2AYLA 1IQJL 6COXA 2Y7ZB 4ISIL 2F9BL 2BQ7A 4LMFA 5EGMB 3MQEA 1ADXA 5FDQA 1EPJA 1ATBA 3IJEB 2WPKE 3KQCL 1NFUB 4BTUA 1BF9A 1URKA 2VWLL 1IJQA 1ZAQA 4AQTA 3HS5A 4MMYB 3PGHA 1NQLB 1IQEL 4O02B 4Y6DB 2W2NE 2NPRA 2P28B 2Y82B 4RRYA 4X8UL 1G1QA 1IOXA 5JVZA 2KB9A 2FZZL 1KLJL 2P93L 1NZIA 1WU1B 1LPGA 5IKVA 3HPTA 2J34B 3LAQA 1LMJA 5F19A 4TGFA 2WPIE 1EPHA 4Y79B 1XKAL 4XBMA 1ATDA 3ZYGA 5CKQA 3HS7A 4Y7BB 3N8VA 2VVUL 2Y38A 2Y7XB 5CKMA 2VH6B 5KN5C 2Q1JB 3KRKA 1LPZA 1AUTL 1YUGA 1YUFA 4COXA 4JYUL 2UWOB 3U73A 2WPHE 3F1SB 1HAFA 1IQML 3FFGL 2J38B 3LIWB 3NTGA 4C16A 1G1TA 1NFYB 1NPEB 1F7MA 2I9AA 2FLRL 1WHEA 1XKBA 5KIRA 1KLOA 4CUFA 1APOA 2VWOL 1G2MB 2Y81B 3QH0A 3M36L 3HO3A 1CQEA 1PRHA 4D0EA 4YT7L 4BTTA 2KV4A 5JBAE 2W2PE 4BDXA 3TGFA 1CCFA 1N1IA 3N8YB 1W7XL 4CUEA 4Y76B 1EMNA 2YGOA 1JL9A 1P9JA 2G00L 3BT2A 2K2TA 1EZQB 1IGZA 1HT5A 2WFTA 2P3FL 3TH3L 2VH0B 3CA7A 2WPME 3FCSB 3LN0A 1HCGB 5F1AA 1EPGA 4A7IA 3EGFA 1HZ8A 2XBXL 3TBDA 3LC3B 3KL6B 1Z6EL 1KLIL 2UWPB 2W2OE 2Y5FL 4XLWA 1UZQA 1CX2A 4BTIA 2BOHA 2WYGB 3KCGL 1QFKL 3TZIA 3IITB 1MQ6L 1V3XB 2BQWA 1WHFA 1IGXA 3C9AC 4M10A 3LC5B 2EI7B 1LPKA 3H5CB 1FF7A 1G1RA 1U8CB 3CFWA 1F0SB 3R05A 4ZAEB 2W3IB 1TPGA 4FM5A 2VVVL 1KSNB 2BOXA 3GCWE 3ZYIB 4JZDL 4X8SL 1HREA 1HAEA 1IOEL 1P0SL 2MHPA 1N7DA 4BXWA 5IKQA 1HX2A 3TK5B 5CKNA 1XDTR 5L2ZL 2Y5GL 4Y7AB 1IVOC 1CVWL 3HS6A 2MGPA 5K0HB 1O5DL 2RHPA 4MMXB 3Q3KB 4RUTA 1RFNB 5JVYA 2BO2A 2BOKL 1EMOA 1YO8A 3ELAL 3N8ZA 3KQEL 2P3FN 2P3TA 4Y71B 2D1JB 1UZKA 4YZUB 3N8XA 2J94B 3CS7L 1IQFL 4PH9A 2MGRA 2RA0L 2XC5L 3GCXE 1HRFA 2YGPA 1LQDA 5CISA 1C5MF 2ADXA 4M11A 1APQA 1YUKB 1PXXA 2J4IB 2W2ME 3POYA 1J9CL 1ATEA 4BXSA 3ASIA 1L3YA 5COXA 4LORA 1G1SA 1A3PA 1IQLL 1DX5I 1FAKL 3QCWA 1HJ7A 4E1GA 1Z6CA 2WG4B 2OYEP 3SOVA 1FAXL 5JBCE 2XBWL 1CCVA 2EI6B 1DQBA 3KK6A 2BZ6L 1FJSL 2P3UA 2EI8B 1JV2B 1UZPA 2K2SB 3SW2A 4RS0A 4Z0LA 1SZBA 1G2LB 2BMGA 4NGAL 1L5GB 3M37L 1NFXB 2CJIB 1FE2A 1XFEA 3Q7DA 1PTHA 2Y5HL 4Z6AL 3QMOA 2J2UB 3DEMA 1K36A 1EPIA 1OB1C 4OTJA 1TOZA 3U7UG 3KQDL 2BQ6A 4X8TL 1NFWB 4G1MB 2VWMK 3OLUA 1IQKL 2B7DL 2P94L 2UWLB 1HT8A 3SOBB 4JZFL 3NTBA 3KQBL 3FBYA 3ZYJB 1TLEA 2W3KB 3BPSE 1EQHA 2VWNL 1COUA 2WFXB 2VVCK 3N8YA 2FD6A 4CUDA 1X7AL 2P16L 2RNLA 4ZH8B 2PHBB 1W8BL 1IQHL 3BT1A 4ZHAB 1EQGA 3K9XA 1B9WA 3LTGD 5IKTA 2WPJE 1F0RB 3V64C 4RRXA 5JW1A 4OTYA 1IQIL 3OLTA 2M74A 2XBYL 4XL1A 1EAIC 2GD4A 2WG3C 4Z0KB 2H9EL 5I46L 5JB9E 1Q4GA 2DDUA 4D0FA 3SOQA 3NJPC 4YT6L 3N8WB 1KIGL 1MOXC 2KL7A 2FLGA 3TK6B 5JB8E 1CEJA 1FSBA 2P95L 4O1ZA 1K37A 2BOUA 3V65B 2J95B 1IQNL 3P5BL 1IP0A 2I9BA 4JZEL 3HO4A 5L30L 1IQGL 4MMZB 5IKRA 1U67A 3NT1A 4D90A 2FLBL 3MDLA 3LTFB 2XBVL 2OYUP 5L2YL 2W2QE 1FFMA 2W26B 4NG9L 2WYJB 3F6UL 3GISX 3RR3A 1F7EA 2XC4L 1DVAL 4X8VL 4ZXXL 4ZXYL 3CENL 2W86A 1UZJA 4RRZA 2XC0L 2Y80B 2PR3B 4ISHL 1I0UA 3LN1A 1JBUL 4BDWA 4JYVL 1ATAA 2JKHL 3HO5A 4RRWA 3ENSA 1MQ5L
chains in the Genus database with same CATH superfamily
1PFXL 1DDXA 1EBVA 5JBBE 2KNIA 1CVUA 1DIYA 1PGEA 1YGCL 2BSFA 2VRSA 4NA9L 2VJ3A 1GK5A 2WPLE 2PUQL 1EGFA 1NT0A 1LMMA 5E8DA 1M1XB 2TGFA 4CSYA 3N8WA 2P26A 2AYLA 1IQJL 6COXA 2Y7ZB 4ISIL 2F9BL 2BQ7A 4LMFA 5EGMB 3MQEA 1ADXA 5FDQA 1EPJA 1ATBA 3IJEB 2WPKE 3KQCL 1NFUB 4BTUA 1BF9A 1URKA 2VWLL 1IJQA 1ZAQA 4AQTA 3HS5A 4MMYB 3PGHA 1NQLB 1IQEL 4O02B 4Y6DB 2W2NE 2NPRA 2P28B 2Y82B 4RRYA 4X8UL 1G1QA 1IOXA 5JVZA 2KB9A 2FZZL 1KLJL 2P93L 1NZIA 1WU1B 1LPGA 5IKVA 3HPTA 2J34B 3LAQA 1LMJA 5F19A 4TGFA 2WPIE 1EPHA 2H9EC 4Y79B 1XKAL 4XBMA 1ATDA 3ZYGA 5CKQA 3HS7A 4Y7BB 3N8VA 2VVUL 2Y38A 2Y7XB 5CKMA 2VH6B 5KN5C 2Q1JB 3KRKA 1LPZA 1AUTL 1YUGA 1YUFA 4COXA 4JYUL 2UWOB 3U73A 2WPHE 2WZPP 3F1SB 1HAFA 1IQML 3FFGL 2J38B 3LIWB 3NTGA 4C16A 1G1TA 1NFYB 1NPEB 1F7MA 2I9AA 2FLRL 1WHEA 1XKBA 5KIRA 1KLOA 4CUFA 1APOA 2VWOL 1G2MB 2Y81B 3QH0A 3M36L 3HO3A 1CQEA 1PRHA 4D0EA 4YT7L 4BTTA 2KV4A 5JBAE 2W2PE 4BDXA 3TGFA 1CCFA 1N1IA 3N8YB 1W7XL 4CUEA 4Y76B 1EMNA 2YGQA 2YGOA 1JL9A 1P9JA 2G00L 3BT2A 2K2TA 1EZQB 1IGZA 1HT5A 2WFTA 2P3FL 3TH3L 2VH0B 3CA7A 2WPME 3FCSB 3LN0A 1HCGB 5F1AA 1EPGA 4A7IA 3EGFA 1HZ8A 2XBXL 3TBDA 3LC3B 3KL6B 1V1HA 1KLIL 1Z6EL 2UWPB 2W2OE 2Y5FL 4XLWA 1UZQA 1CX2A 1LK9A 4BTIA 2BOHA 2WYGB 3KCGL 1QFKL 3TZIA 3IITB 1MQ6L 1V3XB 2BQWA 1WHFA 1IGXA 3C9AC 4M10A 3LC5B 2EI7B 1LPKA 3H5CB 1V1IA 1G1RA 1FF7A 1U8CB 3CFWA 1F0SB 3R05A 4ZAEB 2W3IB 1TPGA 4FM5A 2VVVL 1KSNB 2BOXA 3GCWE 3ZYIB 4JZDL 4X8SL 1HREA 1HAEA 1IOEL 1P0SL 2MHPA 1N7DA 4BXWA 5IKQA 1HX2A 3TK5B 5CKNA 1XDTR 5L2ZL 2Y5GL 4Y7AB 1IVOC 1CVWL 3HS6A 2MGPA 5K0HB 1O5DL 2RHPA 4MMXB 3Q3KB 4RUTA 1RFNB 5JVYA 2BO2A 2BOKL 1EMOA 1YO8A 3ELAL 3N8ZA 3KQEL 2P3FN 2P3TA 4Y71B 2D1JB 1UZKA 4YZUB 3N8XA 2J94B 3CS7L 1IQFL 4PH9A 2MGRA 2RA0L 2XC5L 3GCXE 1HRFA 4GU3A 2YGPA 1LQDA 5CISA 1C5MF 2ADXA 4M11A 1APQA 1YUKB 2HORA 1PXXA 1QIUA 2J4IB 2W2ME 3POYA 1J9CL 1ATEA 4BXSA 3ASIA 1L3YA 5COXA 4LORA 1G1SA 1A3PA 1IQLL 1DX5I 1FAKL 3QCWA 1HJ7A 4E1GA 1Z6CA 2WG4B 2OYEP 3SOVA 1FAXL 5JBCE 2XBWL 1CCVA 2EI6B 1DQBA 3KK6A 2BZ6L 1FJSL 2P3UA 3S6XA 2EI8B 1JV2B 1UZPA 2K2SB 3SW2A 4RS0A 4Z0LA 1SZBA 1G2LB 2BMGA 4NGAL 1L5GB 3M37L 1NFXB 2CJIB 1FE2A 1XFEA 3Q7DA 1PTHA 2Y5HL 4Z6AL 3QMOA 2J2UB 3DEMA 1K36A 1EPIA 1OB1C 4OTJA 1TOZA 3U7UG 3KQDL 2BQ6A 4X8TL 1NFWB 4G1MB 2VWMK 3OLUA 1IQKL 2B7DL 2P94L 2UWLB 1HT8A 3SOBB 4JZFL 3NTBA 3KQBL 3FBYA 3ZYJB 1TLEA 2W3KB 3BPSE 1EQHA 2VWNL 1COUA 2WFXB 2VVCK 3N8YA 2FD6A 4CUDA 1X7AL 2P16L 2RNLA 4ZH8B 2PHBB 1W8BL 1IQHL 3BT1A 4ZHAB 1EQGA 3K9XA 1B9WA 3LTGD 5IKTA 2WPJE 1F0RB 3V64C 4RRXA 5JW1A 4OTYA 1IQIL 3OLTA 4GU4A 2M74A 2XBYL 4XL1A 1EAIC 2GD4A 2WG3C 4Z0KB 1KKEA 4A94C 2H9EL 5I46L 5JB9E 1Q4GA 2DDUA 4D0FA 3SOQA 3NJPC 2BT8A 4YT6L 3N8WB 1KIGL 1MOXC 2KL7A 2FLGA 3TK6B 5JB8E 1CEJA 1FSBA 2P95L 4O1ZA 1K37A 2BT7A 2BOUA 3V65B 2J95B 1IQNL 3P5BL 1IP0A 2I9BA 4JZEL 3HO4A 5L30L 1IQGL 4MMZB 5IKRA 1U67A 3NT1A 4D90A 2FLBL 3MDLA 3LTFB 2XBVL 2OYUP 5L2YL 2W2QE 1FFMA 2W26B 4NG9L 2WYJB 3F6UL 3GISX 3RR3A 1F7EA 2XC4L 1DVAL 2JJLA 4X8VL 4ZXXL 4ZXYL 3CENL 2W86A 1UZJA 4RRZA 2HOXA 2XC0L 2Y80B 2PR3B 4ISHL 1I0UA 3LN1A 1JBUL 4BDWA 4JYVL 1ATAA 2JKHL 3HO5A 4RRWA 3ENSA 1MQ5L
chains in the Genus database with same CATH topology
1PFXL 1DDXA 1EBVA 5JBBE 2KNIA 1CVUA 1DIYA 1PGEA 1YGCL 4NA9L 2VJ3A 1GK5A 2WPLE 2PUQL 1EGFA 1NT0A 1LMMA 5E8DA 1M1XB 2TGFA 4CSYA 3N8WA 2P26A 2AYLA 1IQJL 6COXA 2Y7ZB 4ISIL 2F9BL 2BQ7A 4LMFA 5EGMB 3MQEA 1ADXA 5FDQA 1EPJA 1ATBA 3IJEB 2WPKE 3KQCL 1NFUB 4BTUA 1BF9A 1URKA 2VWLL 1IJQA 1ZAQA 4AQTA 3HS5A 4MMYB 3PGHA 1NQLB 1IQEL 4O02B 4Y6DB 2W2NE 2NPRA 2P28B 2Y82B 4RRYA 4X8UL 1G1QA 1IOXA 5JVZA 2KB9A 2FZZL 1KLJL 2P93L 1NZIA 1WU1B 1LPGA 5IKVA 3HPTA 2J34B 3LAQA 1LMJA 5F19A 4TGFA 2WPIE 1EPHA 2H9EC 4Y79B 1XKAL 4XBMA 1ATDA 3ZYGA 5CKQA 3HS7A 4Y7BB 3N8VA 2VVUL 2Y38A 2Y7XB 5CKMA 2VH6B 5KN5C 2Q1JB 3KRKA 1LPZA 1AUTL 1YUGA 1YUFA 4COXA 4JYUL 2UWOB 3U73A 2WPHE 2WZPP 3F1SB 1HAFA 1IQML 3FFGL 2J38B 3LIWB 3NTGA 4C16A 1G1TA 1NFYB 1NPEB 1F7MA 2I9AA 2FLRL 1WHEA 1XKBA 5KIRA 1KLOA 4CUFA 1APOA 2VWOL 1G2MB 2Y81B 3QH0A 3M36L 3HO3A 1CQEA 1PRHA 4D0EA 4YT7L 4BTTA 2KV4A 5JBAE 2W2PE 4BDXA 3TGFA 1CCFA 1N1IA 3N8YB 1W7XL 4CUEA 4Y76B 1EMNA 2YGQA 2YGOA 1JL9A 1P9JA 2G00L 3BT2A 2K2TA 1EZQB 1IGZA 1HT5A 2WFTA 2P3FL 3TH3L 2VH0B 3CA7A 2WPME 3FCSB 3LN0A 1HCGB 5F1AA 1EPGA 4A7IA 3EGFA 1HZ8A 2XBXL 3TBDA 3LC3B 3KL6B 1Z6EL 1KLIL 2UWPB 2W2OE 2Y5FL 4XLWA 1UZQA 1CX2A 4BTIA 2BOHA 2WYGB 3KCGL 1QFKL 3TZIA 3IITB 1MQ6L 1V3XB 2BQWA 1WHFA 1IGXA 3C9AC 4M10A 3LC5B 2EI7B 1LPKA 3H5CB 1FF7A 1G1RA 1U8CB 3CFWA 1F0SB 3R05A 4ZAEB 2W3IB 1TPGA 4FM5A 2VVVL 1KSNB 2BOXA 3GCWE 3ZYIB 4JZDL 4X8SL 1HREA 1HAEA 1IOEL 1P0SL 2MHPA 1N7DA 4BXWA 5IKQA 1HX2A 3TK5B 5CKNA 1XDTR 5L2ZL 2Y5GL 4Y7AB 1IVOC 1CVWL 3HS6A 2MGPA 5K0HB 1O5DL 2RHPA 4MMXB 3Q3KB 4RUTA 1RFNB 5JVYA 2BO2A 2BOKL 1EMOA 1YO8A 3ELAL 3N8ZA 3KQEL 2P3FN 2P3TA 4Y71B 2D1JB 1UZKA 4YZUB 3N8XA 2J94B 3CS7L 1IQFL 4PH9A 2MGRA 2RA0L 2XC5L 3GCXE 1HRFA 2YGPA 1LQDA 5CISA 1C5MF 2ADXA 4M11A 1APQA 1YUKB 1PXXA 2J4IB 2W2ME 3POYA 1J9CL 1ATEA 4BXSA 3ASIA 1L3YA 5COXA 4LORA 1G1SA 1A3PA 1IQLL 1DX5I 1FAKL 3QCWA 1HJ7A 4E1GA 1Z6CA 2WG4B 2OYEP 3SOVA 1FAXL 5JBCE 2XBWL 1CCVA 2EI6B 1DQBA 3KK6A 2BZ6L 1FJSL 2P3UA 3S6XA 2EI8B 1JV2B 1UZPA 2K2SB 3SW2A 4RS0A 4Z0LA 1SZBA 1G2LB 2BMGA 4NGAL 1L5GB 3M37L 1NFXB 2CJIB 1FE2A 1XFEA 3Q7DA 1PTHA 2Y5HL 4Z6AL 3QMOA 2J2UB 3DEMA 1K36A 1EPIA 1OB1C 4OTJA 1TOZA 3U7UG 3KQDL 2BQ6A 4X8TL 1NFWB 4G1MB 2VWMK 3OLUA 1IQKL 2B7DL 2P94L 2UWLB 1HT8A 3SOBB 4JZFL 3NTBA 3KQBL 3FBYA 3ZYJB 1TLEA 2W3KB 3BPSE 1EQHA 2VWNL 1COUA 2WFXB 2VVCK 3N8YA 2FD6A 4CUDA 1X7AL 2P16L 2RNLA 4ZH8B 2PHBB 1W8BL 1IQHL 3BT1A 4ZHAB 1EQGA 3K9XA 1B9WA 3LTGD 5IKTA 2WPJE 1F0RB 3V64C 4RRXA 5JW1A 4OTYA 1IQIL 3OLTA 2M74A 2XBYL 4XL1A 1EAIC 2GD4A 2WG3C 4Z0KB 4A94C 2H9EL 5I46L 5JB9E 1Q4GA 2DDUA 4D0FA 3SOQA 3NJPC 4YT6L 3N8WB 1KIGL 1MOXC 2KL7A 2FLGA 3TK6B 5JB8E 1CEJA 1FSBA 2P95L 4O1ZA 1K37A 2BOUA 3V65B 2J95B 1IQNL 3P5BL 1IP0A 2I9BA 4JZEL 3HO4A 5L30L 1IQGL 4MMZB 5IKRA 1U67A 3NT1A 4D90A 2FLBL 3MDLA 3LTFB 2XBVL 2OYUP 5L2YL 2W2QE 1FFMA 2W26B 4NG9L 2WYJB 3F6UL 3GISX 3RR3A 1F7EA 2XC4L 1DVAL 4X8VL 4ZXXL 4ZXYL 3CENL 2W86A 1UZJA 4RRZA 2XC0L 2Y80B 2PR3B 4ISHL 1I0UA 3LN1A 1JBUL 4BDWA 4JYVL 1ATAA 2JKHL 3HO5A 4RRWA 3ENSA 1MQ5L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PFX L;  1DDX A;  1EBV A;  5JBB E;  1CVU A;  1DIY A;  1PGE A;  1YGC L;  4NA9 L;  2VJ3 A;  1GK5 A;  2WPL E;  2PUQ L;  1EGF A;  1NT0 A;  5E8D A;  1M1X B;  2TGF A;  4CSY A;  3N8W A;  2P26 A;  2AYL A;  1IQJ L;  6COX A;  2Y7Z B;  4ISI L;  2F9B L;  2BQ7 A;  4LMF A;  5EGM B;  3MQE A;  1ADX A;  5FDQ A;  1EPJ A;  1ATB A;  3IJE B;  2WPK E;  3KQC L;  1NFU B;  4BTU A;  1BF9 A;  1URK A;  2VWL L;  1IJQ A;  1ZAQ A;  4AQT A;  3HS5 A;  4MMY B;  3PGH A;  1NQL B;  1IQE L;  4O02 B;  4Y6D B;  2W2N E;  2NPR A;  2P28 B;  2Y82 B;  4RRY A;  4X8U L;  1G1Q A;  1IOX A;  5JVZ A;  2KB9 A;  2FZZ L;  1KLJ L;  2P93 L;  1NZI A;  1WU1 B;  1LPG A;  5IKV A;  3HPT A;  2J34 B;  3LAQ A;  1LMJ A;  5F19 A;  4TGF A;  2WPI E;  1EPH A;  4Y79 B;  1XKA L;  4XBM A;  1ATD A;  3ZYG A;  5CKQ A;  3HS7 A;  4Y7B B;  3N8V A;  2VVU L;  2Y38 A;  2Y7X B;  5CKM A;  2VH6 B;  5KN5 C;  2Q1J B;  3KRK A;  1LPZ A;  1AUT L;  1YUG A;  1YUF A;  4COX A;  4JYU L;  2UWO B;  3U73 A;  2WPH E;  3F1S B;  1HAF A;  1IQM L;  3FFG L;  2J38 B;  3LIW B;  3NTG A;  4C16 A;  1G1T A;  1NFY B;  1NPE B;  1F7M A;  2I9A A;  2FLR L;  1WHE A;  1XKB A;  5KIR A;  1KLO A;  4CUF A;  1APO A;  2VWO L;  1G2M B;  2Y81 B;  3QH0 A;  3M36 L;  3HO3 A;  1CQE A;  1PRH A;  4D0E A;  4YT7 L;  4BTT A;  2KV4 A;  5JBA E;  2W2P E;  4BDX A;  3TGF A;  1CCF A;  1N1I A;  3N8Y B;  1W7X L;  4CUE A;  4Y76 B;  1EMN A;  2YGO A;  1JL9 A;  1P9J A;  2G00 L;  3BT2 A;  2K2T A;  1EZQ B;  1IGZ A;  1HT5 A;  2WFT A;  2P3F L;  3TH3 L;  2VH0 B;  3CA7 A;  2WPM E;  3FCS B;  3LN0 A;  1HCG B;  5F1A A;  1EPG A;  4A7I A;  3EGF A;  1HZ8 A;  2XBX L;  3TBD A;  3LC3 B;  3KL6 B;  1Z6E L;  1KLI L;  2UWP B;  2W2O E;  2Y5F L;  4XLW A;  1UZQ A;  1CX2 A;  4BTI A;  2BOH A;  2WYG B;  3KCG L;  1QFK L;  3TZI A;  3IIT B;  1MQ6 L;  1V3X B;  2BQW A;  1WHF A;  1IGX A;  3C9A C;  4M10 A;  3LC5 B;  2EI7 B;  1LPK A;  3H5C B;  1FF7 A;  1G1R A;  1U8C B;  3CFW A;  1F0S B;  3R05 A;  4ZAE B;  2W3I B;  1TPG A;  4FM5 A;  2VVV L;  1KSN B;  2BOX A;  3GCW E;  3ZYI B;  4JZD L;  4X8S L;  1HRE A;  1HAE A;  1IOE L;  1P0S L;  2MHP A;  1N7D A;  4BXW A;  5IKQ A;  1HX2 A;  3TK5 B;  5CKN A;  1XDT R;  5L2Z L;  2Y5G L;  4Y7A B;  1IVO C;  1CVW L;  3HS6 A;  2MGP A;  5K0H B;  1O5D L;  2RHP A;  4MMX B;  3Q3K B;  4RUT A;  1RFN B;  5JVY A;  2BO2 A;  2BOK L;  1EMO A;  1YO8 A;  3ELA L;  3N8Z A;  3KQE L;  2P3F N;  2P3T A;  4Y71 B;  2D1J B;  1UZK A;  4YZU B;  3N8X A;  2J94 B;  3CS7 L;  1IQF L;  4PH9 A;  2MGR A;  2RA0 L;  2XC5 L;  3GCX E;  1HRF A;  2YGP A;  1LQD A;  5CIS A;  1C5M F;  2ADX A;  4M11 A;  1APQ A;  1YUK B;  1PXX A;  2J4I B;  2W2M E;  3POY A;  1J9C L;  1ATE A;  4BXS A;  3ASI A;  1L3Y A;  5COX A;  4LOR A;  1G1S A;  1A3P A;  1IQL L;  1DX5 I;  1FAK L;  3QCW A;  1HJ7 A;  4E1G A;  1Z6C A;  2WG4 B;  2OYE P;  3SOV A;  1FAX L;  5JBC E;  2XBW L;  1CCV A;  2EI6 B;  1DQB A;  3KK6 A;  2BZ6 L;  1FJS L;  2P3U A;  2EI8 B;  1JV2 B;  1UZP A;  2K2S B;  3SW2 A;  4RS0 A;  4Z0L A;  1SZB A;  1G2L B;  2BMG A;  4NGA L;  1L5G B;  3M37 L;  1NFX B;  2CJI B;  1FE2 A;  1XFE A;  3Q7D A;  1PTH A;  2Y5H L;  4Z6A L;  3QMO A;  2J2U B;  3DEM A;  1K36 A;  1EPI A;  1OB1 C;  4OTJ A;  1TOZ A;  3U7U G;  3KQD L;  2BQ6 A;  4X8T L;  1NFW B;  4G1M B;  2VWM K;  3OLU A;  1IQK L;  2B7D L;  2P94 L;  2UWL B;  1HT8 A;  3SOB B;  4JZF L;  3NTB A;  3KQB L;  3FBY A;  3ZYJ B;  1TLE A;  2W3K B;  3BPS E;  1EQH A;  2VWN L;  1COU A;  2WFX B;  2VVC K;  3N8Y A;  2FD6 A;  4CUD A;  1X7A L;  2P16 L;  2RNL A;  4ZH8 B;  2PHB B;  1W8B L;  1IQH L;  3BT1 A;  4ZHA B;  1EQG A;  3K9X A;  1B9W A;  3LTG D;  5IKT A;  2WPJ E;  1F0R B;  3V64 C;  4RRX A;  5JW1 A;  4OTY A;  1IQI L;  3OLT A;  2M74 A;  2XBY L;  4XL1 A;  1EAI C;  2GD4 A;  2WG3 C;  4Z0K B;  2H9E L;  5I46 L;  5JB9 E;  1Q4G A;  2DDU A;  4D0F A;  3SOQ A;  3NJP C;  4YT6 L;  3N8W B;  1KIG L;  1MOX C;  2KL7 A;  2FLG A;  3TK6 B;  5JB8 E;  1CEJ A;  1FSB A;  2P95 L;  4O1Z A;  1K37 A;  2BOU A;  3V65 B;  2J95 B;  1IQN L;  3P5B L;  1IP0 A;  2I9B A;  4JZE L;  3HO4 A;  5L30 L;  1IQG L;  4MMZ B;  5IKR A;  1U67 A;  3NT1 A;  4D90 A;  2FLB L;  3MDL A;  3LTF B;  2XBV L;  2OYU P;  5L2Y L;  2W2Q E;  1FFM A;  2W26 B;  4NG9 L;  2WYJ B;  3F6U L;  3GIS X;  3RR3 A;  1F7E A;  2XC4 L;  1DVA L;  4X8V L;  4ZXX L;  4ZXY L;  3CEN L;  2W86 A;  1UZJ A;  4RRZ A;  2XC0 L;  2Y80 B;  2PR3 B;  4ISH L;  1I0U A;  3LN1 A;  1JBU L;  4BDW A;  4JYV L;  1ATA A;  2JKH L;  3HO5 A;  4RRW A;  3ENS A;  1MQ5 L; 
#chains in the Genus database with same CATH topology
 1PFX L;  1DDX A;  1EBV A;  5JBB E;  2KNI A;  1CVU A;  1DIY A;  1PGE A;  1YGC L;  2BSF A;  2VRS A;  4NA9 L;  2VJ3 A;  1GK5 A;  2WPL E;  2PUQ L;  1EGF A;  1NT0 A;  1LMM A;  5E8D A;  1M1X B;  2TGF A;  4CSY A;  3N8W A;  2P26 A;  2AYL A;  1IQJ L;  6COX A;  2Y7Z B;  4ISI L;  2F9B L;  2BQ7 A;  4LMF A;  5EGM B;  3MQE A;  1ADX A;  5FDQ A;  1EPJ A;  1ATB A;  3IJE B;  2WPK E;  3KQC L;  1NFU B;  4BTU A;  1BF9 A;  1URK A;  2VWL L;  1IJQ A;  1ZAQ A;  4AQT A;  3HS5 A;  4MMY B;  3PGH A;  1NQL B;  1IQE L;  4O02 B;  4Y6D B;  2W2N E;  2NPR A;  2P28 B;  2Y82 B;  4RRY A;  4X8U L;  1G1Q A;  1IOX A;  5JVZ A;  2KB9 A;  2FZZ L;  1KLJ L;  2P93 L;  1NZI A;  1WU1 B;  1LPG A;  5IKV A;  3HPT A;  2J34 B;  3LAQ A;  1LMJ A;  5F19 A;  4TGF A;  2WPI E;  1EPH A;  2H9E C;  4Y79 B;  1XKA L;  4XBM A;  1ATD A;  3ZYG A;  5CKQ A;  3HS7 A;  4Y7B B;  3N8V A;  2VVU L;  2Y38 A;  2Y7X B;  5CKM A;  2VH6 B;  5KN5 C;  2Q1J B;  3KRK A;  1LPZ A;  1AUT L;  1YUG A;  1YUF A;  4COX A;  4JYU L;  2UWO B;  3U73 A;  2WPH E;  2WZP P;  3F1S B;  1HAF A;  1IQM L;  3FFG L;  2J38 B;  3LIW B;  3NTG A;  4C16 A;  1G1T A;  1NFY B;  1NPE B;  1F7M A;  2I9A A;  2FLR L;  1WHE A;  1XKB A;  5KIR A;  1KLO A;  4CUF A;  1APO A;  2VWO L;  1G2M B;  2Y81 B;  3QH0 A;  3M36 L;  3HO3 A;  1CQE A;  1PRH A;  4D0E A;  4YT7 L;  4BTT A;  2KV4 A;  5JBA E;  2W2P E;  4BDX A;  3TGF A;  1CCF A;  1N1I A;  3N8Y B;  1W7X L;  4CUE A;  4Y76 B;  1EMN A;  2YGQ A;  2YGO A;  1JL9 A;  1P9J A;  2G00 L;  3BT2 A;  2K2T A;  1EZQ B;  1IGZ A;  1HT5 A;  2WFT A;  2P3F L;  3TH3 L;  2VH0 B;  3CA7 A;  2WPM E;  3FCS B;  3LN0 A;  1HCG B;  5F1A A;  1EPG A;  4A7I A;  3EGF A;  1HZ8 A;  2XBX L;  3TBD A;  3LC3 B;  3KL6 B;  1V1H A;  1KLI L;  1Z6E L;  2UWP B;  2W2O E;  2Y5F L;  4XLW A;  1UZQ A;  1CX2 A;  1LK9 A;  4BTI A;  2BOH A;  2WYG B;  3KCG L;  1QFK L;  3TZI A;  3IIT B;  1MQ6 L;  1V3X B;  2BQW A;  1WHF A;  1IGX A;  3C9A C;  4M10 A;  3LC5 B;  2EI7 B;  1LPK A;  3H5C B;  1V1I A;  1G1R A;  1FF7 A;  1U8C B;  3CFW A;  1F0S B;  3R05 A;  4ZAE B;  2W3I B;  1TPG A;  4FM5 A;  2VVV L;  1KSN B;  2BOX A;  3GCW E;  3ZYI B;  4JZD L;  4X8S L;  1HRE A;  1HAE A;  1IOE L;  1P0S L;  2MHP A;  1N7D A;  4BXW A;  5IKQ A;  1HX2 A;  3TK5 B;  5CKN A;  1XDT R;  5L2Z L;  2Y5G L;  4Y7A B;  1IVO C;  1CVW L;  3HS6 A;  2MGP A;  5K0H B;  1O5D L;  2RHP A;  4MMX B;  3Q3K B;  4RUT A;  1RFN B;  5JVY A;  2BO2 A;  2BOK L;  1EMO A;  1YO8 A;  3ELA L;  3N8Z A;  3KQE L;  2P3F N;  2P3T A;  4Y71 B;  2D1J B;  1UZK A;  4YZU B;  3N8X A;  2J94 B;  3CS7 L;  1IQF L;  4PH9 A;  2MGR A;  2RA0 L;  2XC5 L;  3GCX E;  1HRF A;  4GU3 A;  2YGP A;  1LQD A;  5CIS A;  1C5M F;  2ADX A;  4M11 A;  1APQ A;  1YUK B;  2HOR A;  1PXX A;  1QIU A;  2J4I B;  2W2M E;  3POY A;  1J9C L;  1ATE A;  4BXS A;  3ASI A;  1L3Y A;  5COX A;  4LOR A;  1G1S A;  1A3P A;  1IQL L;  1DX5 I;  1FAK L;  3QCW A;  1HJ7 A;  4E1G A;  1Z6C A;  2WG4 B;  2OYE P;  3SOV A;  1FAX L;  5JBC E;  2XBW L;  1CCV A;  2EI6 B;  1DQB A;  3KK6 A;  2BZ6 L;  1FJS L;  2P3U A;  3S6X A;  2EI8 B;  1JV2 B;  1UZP A;  2K2S B;  3SW2 A;  4RS0 A;  4Z0L A;  1SZB A;  1G2L B;  2BMG A;  4NGA L;  1L5G B;  3M37 L;  1NFX B;  2CJI B;  1FE2 A;  1XFE A;  3Q7D A;  1PTH A;  2Y5H L;  4Z6A L;  3QMO A;  2J2U B;  3DEM A;  1K36 A;  1EPI A;  1OB1 C;  4OTJ A;  1TOZ A;  3U7U G;  3KQD L;  2BQ6 A;  4X8T L;  1NFW B;  4G1M B;  2VWM K;  3OLU A;  1IQK L;  2B7D L;  2P94 L;  2UWL B;  1HT8 A;  3SOB B;  4JZF L;  3NTB A;  3KQB L;  3FBY A;  3ZYJ B;  1TLE A;  2W3K B;  3BPS E;  1EQH A;  2VWN L;  1COU A;  2WFX B;  2VVC K;  3N8Y A;  2FD6 A;  4CUD A;  1X7A L;  2P16 L;  2RNL A;  4ZH8 B;  2PHB B;  1W8B L;  1IQH L;  3BT1 A;  4ZHA B;  1EQG A;  3K9X A;  1B9W A;  3LTG D;  5IKT A;  2WPJ E;  1F0R B;  3V64 C;  4RRX A;  5JW1 A;  4OTY A;  1IQI L;  3OLT A;  4GU4 A;  2M74 A;  2XBY L;  4XL1 A;  1EAI C;  2GD4 A;  2WG3 C;  4Z0K B;  1KKE A;  4A94 C;  2H9E L;  5I46 L;  5JB9 E;  1Q4G A;  2DDU A;  4D0F A;  3SOQ A;  3NJP C;  2BT8 A;  4YT6 L;  3N8W B;  1KIG L;  1MOX C;  2KL7 A;  2FLG A;  3TK6 B;  5JB8 E;  1CEJ A;  1FSB A;  2P95 L;  4O1Z A;  1K37 A;  2BT7 A;  2BOU A;  3V65 B;  2J95 B;  1IQN L;  3P5B L;  1IP0 A;  2I9B A;  4JZE L;  3HO4 A;  5L30 L;  1IQG L;  4MMZ B;  5IKR A;  1U67 A;  3NT1 A;  4D90 A;  2FLB L;  3MDL A;  3LTF B;  2XBV L;  2OYU P;  5L2Y L;  2W2Q E;  1FFM A;  2W26 B;  4NG9 L;  2WYJ B;  3F6U L;  3GIS X;  3RR3 A;  1F7E A;  2XC4 L;  1DVA L;  2JJL A;  4X8V L;  4ZXX L;  4ZXY L;  3CEN L;  2W86 A;  1UZJ A;  4RRZ A;  2HOX A;  2XC0 L;  2Y80 B;  2PR3 B;  4ISH L;  1I0U A;  3LN1 A;  1JBU L;  4BDW A;  4JYV L;  1ATA A;  2JKH L;  3HO5 A;  4RRW A;  3ENS A;  1MQ5 L; 
#chains in the Genus database with same CATH homology
 1PFX L;  1DDX A;  1EBV A;  5JBB E;  2KNI A;  1CVU A;  1DIY A;  1PGE A;  1YGC L;  4NA9 L;  2VJ3 A;  1GK5 A;  2WPL E;  2PUQ L;  1EGF A;  1NT0 A;  1LMM A;  5E8D A;  1M1X B;  2TGF A;  4CSY A;  3N8W A;  2P26 A;  2AYL A;  1IQJ L;  6COX A;  2Y7Z B;  4ISI L;  2F9B L;  2BQ7 A;  4LMF A;  5EGM B;  3MQE A;  1ADX A;  5FDQ A;  1EPJ A;  1ATB A;  3IJE B;  2WPK E;  3KQC L;  1NFU B;  4BTU A;  1BF9 A;  1URK A;  2VWL L;  1IJQ A;  1ZAQ A;  4AQT A;  3HS5 A;  4MMY B;  3PGH A;  1NQL B;  1IQE L;  4O02 B;  4Y6D B;  2W2N E;  2NPR A;  2P28 B;  2Y82 B;  4RRY A;  4X8U L;  1G1Q A;  1IOX A;  5JVZ A;  2KB9 A;  2FZZ L;  1KLJ L;  2P93 L;  1NZI A;  1WU1 B;  1LPG A;  5IKV A;  3HPT A;  2J34 B;  3LAQ A;  1LMJ A;  5F19 A;  4TGF A;  2WPI E;  1EPH A;  2H9E C;  4Y79 B;  1XKA L;  4XBM A;  1ATD A;  3ZYG A;  5CKQ A;  3HS7 A;  4Y7B B;  3N8V A;  2VVU L;  2Y38 A;  2Y7X B;  5CKM A;  2VH6 B;  5KN5 C;  2Q1J B;  3KRK A;  1LPZ A;  1AUT L;  1YUG A;  1YUF A;  4COX A;  4JYU L;  2UWO B;  3U73 A;  2WPH E;  2WZP P;  3F1S B;  1HAF A;  1IQM L;  3FFG L;  2J38 B;  3LIW B;  3NTG A;  4C16 A;  1G1T A;  1NFY B;  1NPE B;  1F7M A;  2I9A A;  2FLR L;  1WHE A;  1XKB A;  5KIR A;  1KLO A;  4CUF A;  1APO A;  2VWO L;  1G2M B;  2Y81 B;  3QH0 A;  3M36 L;  3HO3 A;  1CQE A;  1PRH A;  4D0E A;  4YT7 L;  4BTT A;  2KV4 A;  5JBA E;  2W2P E;  4BDX A;  3TGF A;  1CCF A;  1N1I A;  3N8Y B;  1W7X L;  4CUE A;  4Y76 B;  1EMN A;  2YGQ A;  2YGO A;  1JL9 A;  1P9J A;  2G00 L;  3BT2 A;  2K2T A;  1EZQ B;  1IGZ A;  1HT5 A;  2WFT A;  2P3F L;  3TH3 L;  2VH0 B;  3CA7 A;  2WPM E;  3FCS B;  3LN0 A;  1HCG B;  5F1A A;  1EPG A;  4A7I A;  3EGF A;  1HZ8 A;  2XBX L;  3TBD A;  3LC3 B;  3KL6 B;  1Z6E L;  1KLI L;  2UWP B;  2W2O E;  2Y5F L;  4XLW A;  1UZQ A;  1CX2 A;  4BTI A;  2BOH A;  2WYG B;  3KCG L;  1QFK L;  3TZI A;  3IIT B;  1MQ6 L;  1V3X B;  2BQW A;  1WHF A;  1IGX A;  3C9A C;  4M10 A;  3LC5 B;  2EI7 B;  1LPK A;  3H5C B;  1FF7 A;  1G1R A;  1U8C B;  3CFW A;  1F0S B;  3R05 A;  4ZAE B;  2W3I B;  1TPG A;  4FM5 A;  2VVV L;  1KSN B;  2BOX A;  3GCW E;  3ZYI B;  4JZD L;  4X8S L;  1HRE A;  1HAE A;  1IOE L;  1P0S L;  2MHP A;  1N7D A;  4BXW A;  5IKQ A;  1HX2 A;  3TK5 B;  5CKN A;  1XDT R;  5L2Z L;  2Y5G L;  4Y7A B;  1IVO C;  1CVW L;  3HS6 A;  2MGP A;  5K0H B;  1O5D L;  2RHP A;  4MMX B;  3Q3K B;  4RUT A;  1RFN B;  5JVY A;  2BO2 A;  2BOK L;  1EMO A;  1YO8 A;  3ELA L;  3N8Z A;  3KQE L;  2P3F N;  2P3T A;  4Y71 B;  2D1J B;  1UZK A;  4YZU B;  3N8X A;  2J94 B;  3CS7 L;  1IQF L;  4PH9 A;  2MGR A;  2RA0 L;  2XC5 L;  3GCX E;  1HRF A;  2YGP A;  1LQD A;  5CIS A;  1C5M F;  2ADX A;  4M11 A;  1APQ A;  1YUK B;  1PXX A;  2J4I B;  2W2M E;  3POY A;  1J9C L;  1ATE A;  4BXS A;  3ASI A;  1L3Y A;  5COX A;  4LOR A;  1G1S A;  1A3P A;  1IQL L;  1DX5 I;  1FAK L;  3QCW A;  1HJ7 A;  4E1G A;  1Z6C A;  2WG4 B;  2OYE P;  3SOV A;  1FAX L;  5JBC E;  2XBW L;  1CCV A;  2EI6 B;  1DQB A;  3KK6 A;  2BZ6 L;  1FJS L;  2P3U A;  3S6X A;  2EI8 B;  1JV2 B;  1UZP A;  2K2S B;  3SW2 A;  4RS0 A;  4Z0L A;  1SZB A;  1G2L B;  2BMG A;  4NGA L;  1L5G B;  3M37 L;  1NFX B;  2CJI B;  1FE2 A;  1XFE A;  3Q7D A;  1PTH A;  2Y5H L;  4Z6A L;  3QMO A;  2J2U B;  3DEM A;  1K36 A;  1EPI A;  1OB1 C;  4OTJ A;  1TOZ A;  3U7U G;  3KQD L;  2BQ6 A;  4X8T L;  1NFW B;  4G1M B;  2VWM K;  3OLU A;  1IQK L;  2B7D L;  2P94 L;  2UWL B;  1HT8 A;  3SOB B;  4JZF L;  3NTB A;  3KQB L;  3FBY A;  3ZYJ B;  1TLE A;  2W3K B;  3BPS E;  1EQH A;  2VWN L;  1COU A;  2WFX B;  2VVC K;  3N8Y A;  2FD6 A;  4CUD A;  1X7A L;  2P16 L;  2RNL A;  4ZH8 B;  2PHB B;  1W8B L;  1IQH L;  3BT1 A;  4ZHA B;  1EQG A;  3K9X A;  1B9W A;  3LTG D;  5IKT A;  2WPJ E;  1F0R B;  3V64 C;  4RRX A;  5JW1 A;  4OTY A;  1IQI L;  3OLT A;  2M74 A;  2XBY L;  4XL1 A;  1EAI C;  2GD4 A;  2WG3 C;  4Z0K B;  4A94 C;  2H9E L;  5I46 L;  5JB9 E;  1Q4G A;  2DDU A;  4D0F A;  3SOQ A;  3NJP C;  4YT6 L;  3N8W B;  1KIG L;  1MOX C;  2KL7 A;  2FLG A;  3TK6 B;  5JB8 E;  1CEJ A;  1FSB A;  2P95 L;  4O1Z A;  1K37 A;  2BOU A;  3V65 B;  2J95 B;  1IQN L;  3P5B L;  1IP0 A;  2I9B A;  4JZE L;  3HO4 A;  5L30 L;  1IQG L;  4MMZ B;  5IKR A;  1U67 A;  3NT1 A;  4D90 A;  2FLB L;  3MDL A;  3LTF B;  2XBV L;  2OYU P;  5L2Y L;  2W2Q E;  1FFM A;  2W26 B;  4NG9 L;  2WYJ B;  3F6U L;  3GIS X;  3RR3 A;  1F7E A;  2XC4 L;  1DVA L;  4X8V L;  4ZXX L;  4ZXY L;  3CEN L;  2W86 A;  1UZJ A;  4RRZ A;  2XC0 L;  2Y80 B;  2PR3 B;  4ISH L;  1I0U A;  3LN1 A;  1JBU L;  4BDW A;  4JYV L;  1ATA A;  2JKH L;  3HO5 A;  4RRW A;  3ENS A;  1MQ5 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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