2RA0L

X-ray structure of fxa in complex with 7-fluoroindazole
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
51
structure length
51
Chain Sequence
VCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 7-fluoroindazoles as potent and selective inhibitors of factor xa.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Coagulation factor X
total genus 12
structure length 51
sequence length 51
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2ra0L00
3ELAL 2BOXA 1NFXB 5F19A 4NG9L 3QCWA 3KCGL 1XKBA 1FJSL 3OLUA 2WYJB 1X7AL 4BDWA 4M11A 3TH3L 2P3FL 2XBWL 2J2UB 3KL6B 4YZUB 5IKVA 4BXSA 3IITB 2KL7A 1G2LB 1HRFA 1K36A 1A3PA 1XDTR 4ZXYL 4Y7AB 2EI7B 1EQGA 4RRZA 4CUFA 1DQBA 3GISX 1EPIA 1W7XL 1YGCL 3SW2A 2FD6A 1KSNB 3RR3A 1PTHA 5K0HB 4AQTA 4MMXB 1UZPA 3LC3B 1G2MB 2W3KB 2Q1JB 4OTYA 3HS5A 1LPKA 1ATAA 2ADXA 4X8SL 1IQEL 3QMOA 3MQEA 3ZYJB 1G1RA 1CEJA 2MGPA 2Y5HL 3HO3A 3DEMA 4JZFL 2Y5FL 4A7IA 1LMJA 1LQDA 3V64C 2Y80B 5JB9E 5CISA 1FF7A 1G1SA 5JBBE 1ATDA 5L2YL 1NZIA 2W2ME 1F0RB 3LIWB 4YT7L 4PH9A 2VVCK 1Q4GA 1NFYB 1ZAQA 1L3YA 3QH0A 1G1QA 3LTFB 2VWLL 2P3UA 1EBVA 3ENSA 1CCFA 1MQ6L 2J94B 2TGFA 2P28B 2XBVL 1M1XB 1OB1C 2XBXL 4MMYB 1IGXA 2W26B 3NTGA 3HS6A 3TGFA 1J9CL 4X8VL 1XFEA 2CJIB 1IQML 3NT1A 2GD4A 3ZYIB 3HO5A 4ZHAB 1APQA 3SOBB 2J34B 3ASIA 1Z6EL 4ISIL 2J38B 2FLBL 1TOZA 1NQLB 3CENL 2D1JB 1V3XB 2Y82B 3CS7L 5IKTA 4LMFA 3NTBA 1WHFA 1EGFA 2Y7XB 3N8WB 2P95L 2I9AA 2VWOL 2WFXB 3N8WA 4COXA 1W8BL 3KQBL 2WPIE 5L30L 3CFWA 2W2NE 2J95B 2OYUP 4LORA 4Z0KB 3IJEB 5COXA 1SZBA 1EZQB 5JVYA 1HT8A 2W3IB 1IOEL 2WG4B 1YUKB 1FSBA 1XKAL 1FE2A 2VVVL 4CSYA 3HPTA 3KRKA 1COUA 1IP0A 4E1GA 1CX2A 2G00L 4XL1A 5IKQA 2WPLE 4X8UL 4G1MB 1N7DA 4ZXXL 5F1AA 1MOXC 5I46L 2WPJE 3Q7DA 3N8VA 5IKRA 1DX5I 1UZJA 4MMZB 3LN0A 1EQHA 2W2PE 2P16L 1PFXL 4Y76B 2WFTA 1NFWB 3LAQA 1HCGB 4ISHL 1NFUB 3KQEL 1Z6CA 1GK5A 1EMNA 5CKQA 3V65B 3MDLA 1UZQA 1ATBA 3N8ZA 1KLIL 3FBYA 1IVOC 3PGHA 2YGPA 1MQ5L 2Y81B 1F7EA 1KIGL 1JL9A 2BOHA 3KK6A 2UWPB 2FLGA 4JZDL 2EI6B 4RS0A 5CKNA 3FFGL 2H9EL 2J4IB 4D0EA 3F1SB 2P3FN 2W2OE 1EPGA 1HZ8A 2PHBB 1EPHA 1N1IA 1CVUA 2BZ6L 4Y71B 3HS7A 1HX2A 1IQIL 1HJ7A 1HT5A 2RNLA 1JV2B 4BDXA 4CUEA 2UWLB 2EI8B 3TBDA 4JYVL 4O02B 2Y5GL 2MGRA 1FAXL 2KV4A 2VWMK 4Z0LA 1YUFA 4TGFA 1EMOA 2P3TA 3EGFA 2BMGA 2KB9A 2BOUA 2P26A 2PR3B 2VJ3A 5JBAE 1APOA 3OLTA 1KLOA 4RRXA 1HAEA 2I9BA 1QFKL 1IQNL 2BOKL 4NGAL 4OTJA 3BT2A 3N8XA 2K2SB 4O1ZA 2FZZL 1TPGA 1IQHL 2WPHE 5KIRA 1DDXA 2WG3C 1C5MF 1IQGL 3HO4A 4X8TL 2P93L 3ZYGA 2W86A 3N8YB 1IQJL 5JB8E 1NPEB 4NA9L 2Y7ZB 1WHEA 3N8YA 3SOQA 2VVUL 4Z6AL 3Q3KB 1DIYA 1P9JA 4D0FA 4D90A 6COXA 2NPRA 4JYUL 4Y79B 5FDQA 3SOVA 2MHPA 3U7UG 1IGZA 1F7MA 2XC0L 4FM5A 1WU1B 1FAKL 3F6UL 1IOXA 1G1TA 1NT0A 2PUQL 5E8DA 1CQEA 2VH6B 1JBUL 3LN1A 2WYGB 1ATEA 4RRWA 1F0SB 1U67A 2BO2A 2YGOA 1YUGA 1ADXA 1BF9A 1YO8A 3M36L 2BQ7A 2AYLA 3BT1A 2VH0B 4XLWA 1IQFL 3TZIA 4BTTA 3POYA 2XC4L 4CUDA 4Y7BB 3P5BL 2OYEP 2RHPA 5JBCE 3U73A 2JKHL 2WPME 5L2ZL 1O5DL 5JVZA 2RA0L 3GCWE 2Y38A 1FFMA 1I0UA 1LPZA 1PGEA 2XBYL 1AUTL 2F9BL 1HAFA 1P0SL 3M37L 1URKA 4C16A 1EPJA 1IQKL 3FCSB 1LPGA 1TLEA 3KQDL 3LTGD 1IJQA 3K9XA 4XBMA 1DVAL 2BQWA 2B7DL 2FLRL 3KQCL 4Y6DB 2WPKE 1KLJL 2P94L 2W2QE 4BXWA 2K2TA 1HREA 2XC5L 2DDUA 1PRHA 4BTIA 4JZEL 3TK5B 1UZKA 4BTUA 1EAIC 2M74A 3R05A 5CKMA 1U8CB 1CVWL 3H5CB 3GCXE 4ZH8B 2VWNL 1PXXA 4ZAEB 4M10A 4RRYA 3BPSE 1RFNB 3C9AC 5EGMB 5KN5C 1B9WA 1CCVA 1K37A 3TK6B 3CA7A 4RUTA 1L5GB 5JW1A 2UWOB 1IQLL 4YT6L 2BQ6A 3LC5B 3NJPC
chains in the Genus database with same CATH superfamily
3ELAL 2BOXA 1NFXB 5F19A 4NG9L 3QCWA 3KCGL 1XKBA 1FJSL 3OLUA 2WYJB 1X7AL 4BDWA 4M11A 3TH3L 2P3FL 2XBWL 2J2UB 3KL6B 4YZUB 5IKVA 4BXSA 3IITB 2KL7A 1G2LB 1HRFA 1K36A 1A3PA 1XDTR 4ZXYL 4Y7AB 2EI7B 1EQGA 4RRZA 4CUFA 1DQBA 3GISX 1EPIA 1W7XL 1YGCL 3SW2A 2FD6A 1KSNB 3RR3A 1PTHA 5K0HB 4AQTA 4MMXB 1LK9A 4GU4A 1UZPA 3LC3B 1G2MB 2W3KB 2Q1JB 4OTYA 3HS5A 1LPKA 1ATAA 2ADXA 4X8SL 1IQEL 3QMOA 2HOXA 3MQEA 3ZYJB 1G1RA 1CEJA 2MGPA 2Y5HL 3HO3A 3DEMA 4JZFL 2Y5FL 4A7IA 1LMJA 1LQDA 3V64C 4GU3A 2Y80B 5JB9E 5CISA 1FF7A 1G1SA 5JBBE 1ATDA 5L2YL 1NZIA 1QIUA 2W2ME 2WZPP 1F0RB 3LIWB 4YT7L 4PH9A 2VVCK 1Q4GA 1NFYB 1ZAQA 1L3YA 3QH0A 1G1QA 3LTFB 2VWLL 2P3UA 1EBVA 3ENSA 1CCFA 1MQ6L 2J94B 2TGFA 2P28B 2XBVL 1M1XB 1OB1C 2XBXL 4MMYB 1IGXA 2W26B 3NTGA 2HORA 3HS6A 3TGFA 1J9CL 4X8VL 1XFEA 2CJIB 1IQML 3NT1A 1V1IA 2GD4A 3ZYIB 3HO5A 4ZHAB 1APQA 3SOBB 2J34B 3ASIA 1Z6EL 4ISIL 2J38B 2FLBL 1TOZA 1NQLB 3CENL 2D1JB 1V3XB 2Y82B 3CS7L 5IKTA 4LMFA 3NTBA 1WHFA 1EGFA 2Y7XB 3N8WB 2P95L 2I9AA 2VWOL 2WFXB 3N8WA 4COXA 1W8BL 3KQBL 2WPIE 5L30L 3CFWA 2W2NE 2J95B 2OYUP 4LORA 4Z0KB 3IJEB 5COXA 1SZBA 1EZQB 5JVYA 4A94C 1HT8A 3S6XA 1LMMA 2W3IB 1IOEL 2WG4B 1YUKB 1FSBA 1XKAL 1FE2A 2YGQA 2VVVL 4CSYA 3KRKA 3HPTA 1COUA 1IP0A 4E1GA 1CX2A 2G00L 4XL1A 5IKQA 2H9EC 2WPLE 4X8UL 4G1MB 1N7DA 4ZXXL 5F1AA 1MOXC 5I46L 2WPJE 3Q7DA 3N8VA 5IKRA 1DX5I 1UZJA 4MMZB 3LN0A 1EQHA 2W2PE 2P16L 1PFXL 4Y76B 2WFTA 1NFWB 3LAQA 1HCGB 4ISHL 1NFUB 3KQEL 1Z6CA 1GK5A 1EMNA 5CKQA 3V65B 3MDLA 1UZQA 1ATBA 3N8ZA 1KLIL 3FBYA 1IVOC 3PGHA 2YGPA 1MQ5L 2Y81B 1F7EA 1KIGL 1JL9A 2BOHA 3KK6A 2UWPB 2FLGA 4JZDL 2EI6B 4RS0A 5CKNA 3FFGL 2H9EL 2J4IB 4D0EA 3F1SB 2P3FN 2W2OE 1EPGA 1HZ8A 2PHBB 1EPHA 1N1IA 1CVUA 2BZ6L 4Y71B 3HS7A 1HX2A 1IQIL 1HJ7A 1HT5A 2RNLA 1JV2B 4BDXA 4CUEA 2JJLA 2UWLB 2EI8B 3TBDA 4JYVL 4O02B 2Y5GL 2MGRA 1FAXL 2KV4A 2VWMK 4Z0LA 1YUFA 4TGFA 1EMOA 2P3TA 3EGFA 2BMGA 2KB9A 2BOUA 2P26A 2PR3B 2VJ3A 5JBAE 1APOA 3OLTA 1KLOA 4RRXA 1HAEA 2I9BA 2BT8A 1QFKL 1IQNL 2BOKL 4NGAL 4OTJA 3BT2A 3N8XA 2K2SB 4O1ZA 2FZZL 1TPGA 1IQHL 2WPHE 5KIRA 1DDXA 2WG3C 1C5MF 1IQGL 3HO4A 4X8TL 2P93L 3ZYGA 2W86A 3N8YB 1IQJL 5JB8E 1NPEB 4NA9L 2Y7ZB 1WHEA 3N8YA 2KNIA 3SOQA 2VVUL 4Z6AL 3Q3KB 1DIYA 1P9JA 4D0FA 4D90A 6COXA 2NPRA 4JYUL 2BT7A 4Y79B 5FDQA 3SOVA 2MHPA 3U7UG 1IGZA 1F7MA 2XC0L 4FM5A 1WU1B 2BSFA 1FAKL 3F6UL 1IOXA 1G1TA 1NT0A 2PUQL 5E8DA 1CQEA 2VH6B 1JBUL 1V1HA 3LN1A 2WYGB 1ATEA 4RRWA 1F0SB 1U67A 2BO2A 2YGOA 1YUGA 1ADXA 1BF9A 1YO8A 3M36L 2BQ7A 2AYLA 3BT1A 2VH0B 4XLWA 1IQFL 3TZIA 4BTTA 3POYA 2XC4L 4CUDA 4Y7BB 3P5BL 2OYEP 2RHPA 2VRSA 5JBCE 3U73A 2JKHL 2WPME 5L2ZL 1O5DL 5JVZA 2RA0L 3GCWE 2Y38A 1FFMA 1I0UA 1LPZA 1PGEA 2XBYL 1AUTL 2F9BL 1HAFA 1P0SL 3M37L 1URKA 4C16A 1EPJA 1IQKL 3FCSB 1LPGA 1TLEA 3KQDL 3LTGD 1IJQA 3K9XA 4XBMA 1KKEA 1DVAL 2BQWA 2B7DL 2FLRL 3KQCL 4Y6DB 2WPKE 1KLJL 2P94L 2W2QE 4BXWA 2K2TA 1HREA 2XC5L 2DDUA 1PRHA 4BTIA 4JZEL 3TK5B 1UZKA 4BTUA 1EAIC 2M74A 3R05A 5CKMA 1U8CB 1CVWL 3H5CB 3GCXE 4ZH8B 2VWNL 1PXXA 4ZAEB 4M10A 4RRYA 3BPSE 1RFNB 3C9AC 5EGMB 5KN5C 1B9WA 1CCVA 1K37A 3TK6B 3CA7A 4RUTA 1L5GB 5JW1A 2UWOB 1IQLL 4YT6L 2BQ6A 3LC5B 3NJPC
chains in the Genus database with same CATH topology
3ELAL 2BOXA 1NFXB 5F19A 4NG9L 3QCWA 3KCGL 1XKBA 1FJSL 3OLUA 2WYJB 1X7AL 4BDWA 4M11A 3TH3L 2P3FL 2XBWL 2J2UB 3KL6B 4YZUB 5IKVA 4BXSA 3IITB 2KL7A 1G2LB 1HRFA 1K36A 1A3PA 1XDTR 4ZXYL 4Y7AB 2EI7B 1EQGA 4RRZA 4CUFA 1DQBA 3GISX 1EPIA 1W7XL 1YGCL 3SW2A 2FD6A 1KSNB 3RR3A 1PTHA 5K0HB 4AQTA 4MMXB 1UZPA 3LC3B 1G2MB 2W3KB 2Q1JB 4OTYA 3HS5A 1LPKA 1ATAA 2ADXA 4X8SL 1IQEL 3QMOA 3MQEA 3ZYJB 1G1RA 1CEJA 2MGPA 2Y5HL 3HO3A 3DEMA 4JZFL 2Y5FL 4A7IA 1LMJA 1LQDA 3V64C 2Y80B 5JB9E 5CISA 1FF7A 1G1SA 5JBBE 1ATDA 5L2YL 1NZIA 2W2ME 2WZPP 1F0RB 3LIWB 4YT7L 4PH9A 2VVCK 1Q4GA 1NFYB 1ZAQA 1L3YA 3QH0A 1G1QA 3LTFB 2VWLL 2P3UA 1EBVA 3ENSA 1CCFA 1MQ6L 2J94B 2TGFA 2P28B 2XBVL 1M1XB 1OB1C 2XBXL 4MMYB 1IGXA 2W26B 3NTGA 3HS6A 3TGFA 1J9CL 4X8VL 1XFEA 2CJIB 1IQML 3NT1A 2GD4A 3ZYIB 3HO5A 4ZHAB 1APQA 3SOBB 2J34B 3ASIA 1Z6EL 4ISIL 2J38B 2FLBL 1TOZA 1NQLB 3CENL 2D1JB 1V3XB 2Y82B 3CS7L 5IKTA 4LMFA 3NTBA 1WHFA 1EGFA 2Y7XB 3N8WB 2P95L 2I9AA 2VWOL 2WFXB 3N8WA 4COXA 1W8BL 3KQBL 2WPIE 5L30L 3CFWA 2W2NE 2J95B 2OYUP 4LORA 4Z0KB 3IJEB 5COXA 1SZBA 1EZQB 5JVYA 4A94C 1HT8A 3S6XA 1LMMA 2W3IB 1IOEL 2WG4B 1YUKB 1FSBA 1XKAL 1FE2A 2YGQA 2VVVL 4CSYA 3HPTA 3KRKA 1COUA 1IP0A 4E1GA 1CX2A 2G00L 4XL1A 5IKQA 2H9EC 2WPLE 4X8UL 4G1MB 1N7DA 4ZXXL 5F1AA 1MOXC 5I46L 2WPJE 3Q7DA 3N8VA 5IKRA 1DX5I 1UZJA 4MMZB 3LN0A 1EQHA 2W2PE 2P16L 1PFXL 4Y76B 2WFTA 1NFWB 3LAQA 1HCGB 4ISHL 1NFUB 3KQEL 1Z6CA 1GK5A 1EMNA 5CKQA 3V65B 3MDLA 1UZQA 1ATBA 3N8ZA 1KLIL 3FBYA 1IVOC 3PGHA 2YGPA 1MQ5L 2Y81B 1F7EA 1KIGL 1JL9A 2BOHA 3KK6A 2UWPB 2FLGA 4JZDL 2EI6B 4RS0A 5CKNA 3FFGL 2H9EL 2J4IB 4D0EA 3F1SB 2P3FN 2W2OE 1EPGA 1HZ8A 2PHBB 1EPHA 1N1IA 1CVUA 2BZ6L 4Y71B 3HS7A 1HX2A 1IQIL 1HJ7A 1HT5A 2RNLA 1JV2B 4BDXA 4CUEA 2UWLB 2EI8B 3TBDA 4JYVL 4O02B 2Y5GL 2MGRA 1FAXL 2KV4A 2VWMK 4Z0LA 1YUFA 4TGFA 1EMOA 2P3TA 3EGFA 2BMGA 2KB9A 2BOUA 2P26A 2PR3B 2VJ3A 5JBAE 1APOA 3OLTA 1KLOA 4RRXA 1HAEA 2I9BA 1QFKL 1IQNL 2BOKL 4NGAL 4OTJA 3BT2A 3N8XA 2K2SB 4O1ZA 2FZZL 1TPGA 1IQHL 2WPHE 5KIRA 1DDXA 2WG3C 1C5MF 1IQGL 3HO4A 4X8TL 2P93L 3ZYGA 2W86A 3N8YB 1IQJL 5JB8E 1NPEB 4NA9L 2Y7ZB 1WHEA 3N8YA 2KNIA 3SOQA 2VVUL 4Z6AL 3Q3KB 1DIYA 1P9JA 4D0FA 4D90A 6COXA 2NPRA 4JYUL 4Y79B 5FDQA 3SOVA 2MHPA 3U7UG 1IGZA 1F7MA 2XC0L 4FM5A 1WU1B 1FAKL 3F6UL 1IOXA 1G1TA 1NT0A 2PUQL 5E8DA 1CQEA 2VH6B 1JBUL 3LN1A 2WYGB 1ATEA 4RRWA 1F0SB 1U67A 2BO2A 2YGOA 1YUGA 1ADXA 1BF9A 1YO8A 3M36L 2BQ7A 2AYLA 3BT1A 2VH0B 4XLWA 1IQFL 3TZIA 4BTTA 3POYA 2XC4L 4CUDA 4Y7BB 3P5BL 2OYEP 2RHPA 5JBCE 3U73A 2JKHL 2WPME 5L2ZL 1O5DL 5JVZA 2RA0L 3GCWE 2Y38A 1FFMA 1I0UA 1LPZA 1PGEA 2XBYL 1AUTL 2F9BL 1HAFA 1P0SL 3M37L 1URKA 4C16A 1EPJA 1IQKL 3FCSB 1LPGA 1TLEA 3KQDL 3LTGD 1IJQA 3K9XA 4XBMA 1DVAL 2BQWA 2B7DL 2FLRL 3KQCL 4Y6DB 2WPKE 1KLJL 2P94L 2W2QE 4BXWA 2K2TA 1HREA 2XC5L 2DDUA 1PRHA 4BTIA 4JZEL 3TK5B 1UZKA 4BTUA 1EAIC 2M74A 3R05A 5CKMA 1U8CB 1CVWL 3H5CB 3GCXE 4ZH8B 2VWNL 1PXXA 4ZAEB 4M10A 4RRYA 3BPSE 1RFNB 3C9AC 5EGMB 5KN5C 1B9WA 1CCVA 1K37A 3TK6B 3CA7A 4RUTA 1L5GB 5JW1A 2UWOB 1IQLL 4YT6L 2BQ6A 3LC5B 3NJPC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ELA L;  2BOX A;  1NFX B;  5F19 A;  4NG9 L;  3QCW A;  3KCG L;  1XKB A;  1FJS L;  3OLU A;  2WYJ B;  1X7A L;  4BDW A;  4M11 A;  3TH3 L;  2P3F L;  2XBW L;  2J2U B;  3KL6 B;  4YZU B;  5IKV A;  4BXS A;  3IIT B;  2KL7 A;  1G2L B;  1HRF A;  1K36 A;  1A3P A;  1XDT R;  4ZXY L;  4Y7A B;  2EI7 B;  1EQG A;  4RRZ A;  4CUF A;  1DQB A;  3GIS X;  1EPI A;  1W7X L;  1YGC L;  3SW2 A;  2FD6 A;  1KSN B;  3RR3 A;  1PTH A;  5K0H B;  4AQT A;  4MMX B;  1UZP A;  3LC3 B;  1G2M B;  2W3K B;  2Q1J B;  4OTY A;  3HS5 A;  1LPK A;  1ATA A;  2ADX A;  4X8S L;  1IQE L;  3QMO A;  3MQE A;  3ZYJ B;  1G1R A;  1CEJ A;  2MGP A;  2Y5H L;  3HO3 A;  3DEM A;  4JZF L;  2Y5F L;  4A7I A;  1LMJ A;  1LQD A;  3V64 C;  2Y80 B;  5JB9 E;  5CIS A;  1FF7 A;  1G1S A;  5JBB E;  1ATD A;  5L2Y L;  1NZI A;  2W2M E;  1F0R B;  3LIW B;  4YT7 L;  4PH9 A;  2VVC K;  1Q4G A;  1NFY B;  1ZAQ A;  1L3Y A;  3QH0 A;  1G1Q A;  3LTF B;  2VWL L;  2P3U A;  1EBV A;  3ENS A;  1CCF A;  1MQ6 L;  2J94 B;  2TGF A;  2P28 B;  2XBV L;  1M1X B;  1OB1 C;  2XBX L;  4MMY B;  1IGX A;  2W26 B;  3NTG A;  3HS6 A;  3TGF A;  1J9C L;  4X8V L;  1XFE A;  2CJI B;  1IQM L;  3NT1 A;  2GD4 A;  3ZYI B;  3HO5 A;  4ZHA B;  1APQ A;  3SOB B;  2J34 B;  3ASI A;  1Z6E L;  4ISI L;  2J38 B;  2FLB L;  1TOZ A;  1NQL B;  3CEN L;  2D1J B;  1V3X B;  2Y82 B;  3CS7 L;  5IKT A;  4LMF A;  3NTB A;  1WHF A;  1EGF A;  2Y7X B;  3N8W B;  2P95 L;  2I9A A;  2VWO L;  2WFX B;  3N8W A;  4COX A;  1W8B L;  3KQB L;  2WPI E;  5L30 L;  3CFW A;  2W2N E;  2J95 B;  2OYU P;  4LOR A;  4Z0K B;  3IJE B;  5COX A;  1SZB A;  1EZQ B;  5JVY A;  1HT8 A;  2W3I B;  1IOE L;  2WG4 B;  1YUK B;  1FSB A;  1XKA L;  1FE2 A;  2VVV L;  4CSY A;  3HPT A;  3KRK A;  1COU A;  1IP0 A;  4E1G A;  1CX2 A;  2G00 L;  4XL1 A;  5IKQ A;  2WPL E;  4X8U L;  4G1M B;  1N7D A;  4ZXX L;  5F1A A;  1MOX C;  5I46 L;  2WPJ E;  3Q7D A;  3N8V A;  5IKR A;  1DX5 I;  1UZJ A;  4MMZ B;  3LN0 A;  1EQH A;  2W2P E;  2P16 L;  1PFX L;  4Y76 B;  2WFT A;  1NFW B;  3LAQ A;  1HCG B;  4ISH L;  1NFU B;  3KQE L;  1Z6C A;  1GK5 A;  1EMN A;  5CKQ A;  3V65 B;  3MDL A;  1UZQ A;  1ATB A;  3N8Z A;  1KLI L;  3FBY A;  1IVO C;  3PGH A;  2YGP A;  1MQ5 L;  2Y81 B;  1F7E A;  1KIG L;  1JL9 A;  2BOH A;  3KK6 A;  2UWP B;  2FLG A;  4JZD L;  2EI6 B;  4RS0 A;  5CKN A;  3FFG L;  2H9E L;  2J4I B;  4D0E A;  3F1S B;  2P3F N;  2W2O E;  1EPG A;  1HZ8 A;  2PHB B;  1EPH A;  1N1I A;  1CVU A;  2BZ6 L;  4Y71 B;  3HS7 A;  1HX2 A;  1IQI L;  1HJ7 A;  1HT5 A;  2RNL A;  1JV2 B;  4BDX A;  4CUE A;  2UWL B;  2EI8 B;  3TBD A;  4JYV L;  4O02 B;  2Y5G L;  2MGR A;  1FAX L;  2KV4 A;  2VWM K;  4Z0L A;  1YUF A;  4TGF A;  1EMO A;  2P3T A;  3EGF A;  2BMG A;  2KB9 A;  2BOU A;  2P26 A;  2PR3 B;  2VJ3 A;  5JBA E;  1APO A;  3OLT A;  1KLO A;  4RRX A;  1HAE A;  2I9B A;  1QFK L;  1IQN L;  2BOK L;  4NGA L;  4OTJ A;  3BT2 A;  3N8X A;  2K2S B;  4O1Z A;  2FZZ L;  1TPG A;  1IQH L;  2WPH E;  5KIR A;  1DDX A;  2WG3 C;  1C5M F;  1IQG L;  3HO4 A;  4X8T L;  2P93 L;  3ZYG A;  2W86 A;  3N8Y B;  1IQJ L;  5JB8 E;  1NPE B;  4NA9 L;  2Y7Z B;  1WHE A;  3N8Y A;  3SOQ A;  2VVU L;  4Z6A L;  3Q3K B;  1DIY A;  1P9J A;  4D0F A;  4D90 A;  6COX A;  2NPR A;  4JYU L;  4Y79 B;  5FDQ A;  3SOV A;  2MHP A;  3U7U G;  1IGZ A;  1F7M A;  2XC0 L;  4FM5 A;  1WU1 B;  1FAK L;  3F6U L;  1IOX A;  1G1T A;  1NT0 A;  2PUQ L;  5E8D A;  1CQE A;  2VH6 B;  1JBU L;  3LN1 A;  2WYG B;  1ATE A;  4RRW A;  1F0S B;  1U67 A;  2BO2 A;  2YGO A;  1YUG A;  1ADX A;  1BF9 A;  1YO8 A;  3M36 L;  2BQ7 A;  2AYL A;  3BT1 A;  2VH0 B;  4XLW A;  1IQF L;  3TZI A;  4BTT A;  3POY A;  2XC4 L;  4CUD A;  4Y7B B;  3P5B L;  2OYE P;  2RHP A;  5JBC E;  3U73 A;  2JKH L;  2WPM E;  5L2Z L;  1O5D L;  5JVZ A;  2RA0 L;  3GCW E;  2Y38 A;  1FFM A;  1I0U A;  1LPZ A;  1PGE A;  2XBY L;  1AUT L;  2F9B L;  1HAF A;  1P0S L;  3M37 L;  1URK A;  4C16 A;  1EPJ A;  1IQK L;  3FCS B;  1LPG A;  1TLE A;  3KQD L;  3LTG D;  1IJQ A;  3K9X A;  4XBM A;  1DVA L;  2BQW A;  2B7D L;  2FLR L;  3KQC L;  4Y6D B;  2WPK E;  1KLJ L;  2P94 L;  2W2Q E;  4BXW A;  2K2T A;  1HRE A;  2XC5 L;  2DDU A;  1PRH A;  4BTI A;  4JZE L;  3TK5 B;  1UZK A;  4BTU A;  1EAI C;  2M74 A;  3R05 A;  5CKM A;  1U8C B;  1CVW L;  3H5C B;  3GCX E;  4ZH8 B;  2VWN L;  1PXX A;  4ZAE B;  4M10 A;  4RRY A;  3BPS E;  1RFN B;  3C9A C;  5EGM B;  5KN5 C;  1B9W A;  1CCV A;  1K37 A;  3TK6 B;  3CA7 A;  4RUT A;  1L5G B;  5JW1 A;  2UWO B;  1IQL L;  4YT6 L;  2BQ6 A;  3LC5 B;  3NJP C; 
#chains in the Genus database with same CATH topology
 3ELA L;  2BOX A;  1NFX B;  5F19 A;  4NG9 L;  3QCW A;  3KCG L;  1XKB A;  1FJS L;  3OLU A;  2WYJ B;  1X7A L;  4BDW A;  4M11 A;  3TH3 L;  2P3F L;  2XBW L;  2J2U B;  3KL6 B;  4YZU B;  5IKV A;  4BXS A;  3IIT B;  2KL7 A;  1G2L B;  1HRF A;  1K36 A;  1A3P A;  1XDT R;  4ZXY L;  4Y7A B;  2EI7 B;  1EQG A;  4RRZ A;  4CUF A;  1DQB A;  3GIS X;  1EPI A;  1W7X L;  1YGC L;  3SW2 A;  2FD6 A;  1KSN B;  3RR3 A;  1PTH A;  5K0H B;  4AQT A;  4MMX B;  1LK9 A;  4GU4 A;  1UZP A;  3LC3 B;  1G2M B;  2W3K B;  2Q1J B;  4OTY A;  3HS5 A;  1LPK A;  1ATA A;  2ADX A;  4X8S L;  1IQE L;  3QMO A;  2HOX A;  3MQE A;  3ZYJ B;  1G1R A;  1CEJ A;  2MGP A;  2Y5H L;  3HO3 A;  3DEM A;  4JZF L;  2Y5F L;  4A7I A;  1LMJ A;  1LQD A;  3V64 C;  4GU3 A;  2Y80 B;  5JB9 E;  5CIS A;  1FF7 A;  1G1S A;  5JBB E;  1ATD A;  5L2Y L;  1NZI A;  1QIU A;  2W2M E;  2WZP P;  1F0R B;  3LIW B;  4YT7 L;  4PH9 A;  2VVC K;  1Q4G A;  1NFY B;  1ZAQ A;  1L3Y A;  3QH0 A;  1G1Q A;  3LTF B;  2VWL L;  2P3U A;  1EBV A;  3ENS A;  1CCF A;  1MQ6 L;  2J94 B;  2TGF A;  2P28 B;  2XBV L;  1M1X B;  1OB1 C;  2XBX L;  4MMY B;  1IGX A;  2W26 B;  3NTG A;  2HOR A;  3HS6 A;  3TGF A;  1J9C L;  4X8V L;  1XFE A;  2CJI B;  1IQM L;  3NT1 A;  1V1I A;  2GD4 A;  3ZYI B;  3HO5 A;  4ZHA B;  1APQ A;  3SOB B;  2J34 B;  3ASI A;  1Z6E L;  4ISI L;  2J38 B;  2FLB L;  1TOZ A;  1NQL B;  3CEN L;  2D1J B;  1V3X B;  2Y82 B;  3CS7 L;  5IKT A;  4LMF A;  3NTB A;  1WHF A;  1EGF A;  2Y7X B;  3N8W B;  2P95 L;  2I9A A;  2VWO L;  2WFX B;  3N8W A;  4COX A;  1W8B L;  3KQB L;  2WPI E;  5L30 L;  3CFW A;  2W2N E;  2J95 B;  2OYU P;  4LOR A;  4Z0K B;  3IJE B;  5COX A;  1SZB A;  1EZQ B;  5JVY A;  4A94 C;  1HT8 A;  3S6X A;  1LMM A;  2W3I B;  1IOE L;  2WG4 B;  1YUK B;  1FSB A;  1XKA L;  1FE2 A;  2YGQ A;  2VVV L;  4CSY A;  3KRK A;  3HPT A;  1COU A;  1IP0 A;  4E1G A;  1CX2 A;  2G00 L;  4XL1 A;  5IKQ A;  2H9E C;  2WPL E;  4X8U L;  4G1M B;  1N7D A;  4ZXX L;  5F1A A;  1MOX C;  5I46 L;  2WPJ E;  3Q7D A;  3N8V A;  5IKR A;  1DX5 I;  1UZJ A;  4MMZ B;  3LN0 A;  1EQH A;  2W2P E;  2P16 L;  1PFX L;  4Y76 B;  2WFT A;  1NFW B;  3LAQ A;  1HCG B;  4ISH L;  1NFU B;  3KQE L;  1Z6C A;  1GK5 A;  1EMN A;  5CKQ A;  3V65 B;  3MDL A;  1UZQ A;  1ATB A;  3N8Z A;  1KLI L;  3FBY A;  1IVO C;  3PGH A;  2YGP A;  1MQ5 L;  2Y81 B;  1F7E A;  1KIG L;  1JL9 A;  2BOH A;  3KK6 A;  2UWP B;  2FLG A;  4JZD L;  2EI6 B;  4RS0 A;  5CKN A;  3FFG L;  2H9E L;  2J4I B;  4D0E A;  3F1S B;  2P3F N;  2W2O E;  1EPG A;  1HZ8 A;  2PHB B;  1EPH A;  1N1I A;  1CVU A;  2BZ6 L;  4Y71 B;  3HS7 A;  1HX2 A;  1IQI L;  1HJ7 A;  1HT5 A;  2RNL A;  1JV2 B;  4BDX A;  4CUE A;  2JJL A;  2UWL B;  2EI8 B;  3TBD A;  4JYV L;  4O02 B;  2Y5G L;  2MGR A;  1FAX L;  2KV4 A;  2VWM K;  4Z0L A;  1YUF A;  4TGF A;  1EMO A;  2P3T A;  3EGF A;  2BMG A;  2KB9 A;  2BOU A;  2P26 A;  2PR3 B;  2VJ3 A;  5JBA E;  1APO A;  3OLT A;  1KLO A;  4RRX A;  1HAE A;  2I9B A;  2BT8 A;  1QFK L;  1IQN L;  2BOK L;  4NGA L;  4OTJ A;  3BT2 A;  3N8X A;  2K2S B;  4O1Z A;  2FZZ L;  1TPG A;  1IQH L;  2WPH E;  5KIR A;  1DDX A;  2WG3 C;  1C5M F;  1IQG L;  3HO4 A;  4X8T L;  2P93 L;  3ZYG A;  2W86 A;  3N8Y B;  1IQJ L;  5JB8 E;  1NPE B;  4NA9 L;  2Y7Z B;  1WHE A;  3N8Y A;  2KNI A;  3SOQ A;  2VVU L;  4Z6A L;  3Q3K B;  1DIY A;  1P9J A;  4D0F A;  4D90 A;  6COX A;  2NPR A;  4JYU L;  2BT7 A;  4Y79 B;  5FDQ A;  3SOV A;  2MHP A;  3U7U G;  1IGZ A;  1F7M A;  2XC0 L;  4FM5 A;  1WU1 B;  2BSF A;  1FAK L;  3F6U L;  1IOX A;  1G1T A;  1NT0 A;  2PUQ L;  5E8D A;  1CQE A;  2VH6 B;  1JBU L;  1V1H A;  3LN1 A;  2WYG B;  1ATE A;  4RRW A;  1F0S B;  1U67 A;  2BO2 A;  2YGO A;  1YUG A;  1ADX A;  1BF9 A;  1YO8 A;  3M36 L;  2BQ7 A;  2AYL A;  3BT1 A;  2VH0 B;  4XLW A;  1IQF L;  3TZI A;  4BTT A;  3POY A;  2XC4 L;  4CUD A;  4Y7B B;  3P5B L;  2OYE P;  2RHP A;  2VRS A;  5JBC E;  3U73 A;  2JKH L;  2WPM E;  5L2Z L;  1O5D L;  5JVZ A;  2RA0 L;  3GCW E;  2Y38 A;  1FFM A;  1I0U A;  1LPZ A;  1PGE A;  2XBY L;  1AUT L;  2F9B L;  1HAF A;  1P0S L;  3M37 L;  1URK A;  4C16 A;  1EPJ A;  1IQK L;  3FCS B;  1LPG A;  1TLE A;  3KQD L;  3LTG D;  1IJQ A;  3K9X A;  4XBM A;  1KKE A;  1DVA L;  2BQW A;  2B7D L;  2FLR L;  3KQC L;  4Y6D B;  2WPK E;  1KLJ L;  2P94 L;  2W2Q E;  4BXW A;  2K2T A;  1HRE A;  2XC5 L;  2DDU A;  1PRH A;  4BTI A;  4JZE L;  3TK5 B;  1UZK A;  4BTU A;  1EAI C;  2M74 A;  3R05 A;  5CKM A;  1U8C B;  1CVW L;  3H5C B;  3GCX E;  4ZH8 B;  2VWN L;  1PXX A;  4ZAE B;  4M10 A;  4RRY A;  3BPS E;  1RFN B;  3C9A C;  5EGM B;  5KN5 C;  1B9W A;  1CCV A;  1K37 A;  3TK6 B;  3CA7 A;  4RUT A;  1L5G B;  5JW1 A;  2UWO B;  1IQL L;  4YT6 L;  2BQ6 A;  3LC5 B;  3NJP C; 
#chains in the Genus database with same CATH homology
 3ELA L;  2BOX A;  1NFX B;  5F19 A;  4NG9 L;  3QCW A;  3KCG L;  1XKB A;  1FJS L;  3OLU A;  2WYJ B;  1X7A L;  4BDW A;  4M11 A;  3TH3 L;  2P3F L;  2XBW L;  2J2U B;  3KL6 B;  4YZU B;  5IKV A;  4BXS A;  3IIT B;  2KL7 A;  1G2L B;  1HRF A;  1K36 A;  1A3P A;  1XDT R;  4ZXY L;  4Y7A B;  2EI7 B;  1EQG A;  4RRZ A;  4CUF A;  1DQB A;  3GIS X;  1EPI A;  1W7X L;  1YGC L;  3SW2 A;  2FD6 A;  1KSN B;  3RR3 A;  1PTH A;  5K0H B;  4AQT A;  4MMX B;  1UZP A;  3LC3 B;  1G2M B;  2W3K B;  2Q1J B;  4OTY A;  3HS5 A;  1LPK A;  1ATA A;  2ADX A;  4X8S L;  1IQE L;  3QMO A;  3MQE A;  3ZYJ B;  1G1R A;  1CEJ A;  2MGP A;  2Y5H L;  3HO3 A;  3DEM A;  4JZF L;  2Y5F L;  4A7I A;  1LMJ A;  1LQD A;  3V64 C;  2Y80 B;  5JB9 E;  5CIS A;  1FF7 A;  1G1S A;  5JBB E;  1ATD A;  5L2Y L;  1NZI A;  2W2M E;  2WZP P;  1F0R B;  3LIW B;  4YT7 L;  4PH9 A;  2VVC K;  1Q4G A;  1NFY B;  1ZAQ A;  1L3Y A;  3QH0 A;  1G1Q A;  3LTF B;  2VWL L;  2P3U A;  1EBV A;  3ENS A;  1CCF A;  1MQ6 L;  2J94 B;  2TGF A;  2P28 B;  2XBV L;  1M1X B;  1OB1 C;  2XBX L;  4MMY B;  1IGX A;  2W26 B;  3NTG A;  3HS6 A;  3TGF A;  1J9C L;  4X8V L;  1XFE A;  2CJI B;  1IQM L;  3NT1 A;  2GD4 A;  3ZYI B;  3HO5 A;  4ZHA B;  1APQ A;  3SOB B;  2J34 B;  3ASI A;  1Z6E L;  4ISI L;  2J38 B;  2FLB L;  1TOZ A;  1NQL B;  3CEN L;  2D1J B;  1V3X B;  2Y82 B;  3CS7 L;  5IKT A;  4LMF A;  3NTB A;  1WHF A;  1EGF A;  2Y7X B;  3N8W B;  2P95 L;  2I9A A;  2VWO L;  2WFX B;  3N8W A;  4COX A;  1W8B L;  3KQB L;  2WPI E;  5L30 L;  3CFW A;  2W2N E;  2J95 B;  2OYU P;  4LOR A;  4Z0K B;  3IJE B;  5COX A;  1SZB A;  1EZQ B;  5JVY A;  4A94 C;  1HT8 A;  3S6X A;  1LMM A;  2W3I B;  1IOE L;  2WG4 B;  1YUK B;  1FSB A;  1XKA L;  1FE2 A;  2YGQ A;  2VVV L;  4CSY A;  3HPT A;  3KRK A;  1COU A;  1IP0 A;  4E1G A;  1CX2 A;  2G00 L;  4XL1 A;  5IKQ A;  2H9E C;  2WPL E;  4X8U L;  4G1M B;  1N7D A;  4ZXX L;  5F1A A;  1MOX C;  5I46 L;  2WPJ E;  3Q7D A;  3N8V A;  5IKR A;  1DX5 I;  1UZJ A;  4MMZ B;  3LN0 A;  1EQH A;  2W2P E;  2P16 L;  1PFX L;  4Y76 B;  2WFT A;  1NFW B;  3LAQ A;  1HCG B;  4ISH L;  1NFU B;  3KQE L;  1Z6C A;  1GK5 A;  1EMN A;  5CKQ A;  3V65 B;  3MDL A;  1UZQ A;  1ATB A;  3N8Z A;  1KLI L;  3FBY A;  1IVO C;  3PGH A;  2YGP A;  1MQ5 L;  2Y81 B;  1F7E A;  1KIG L;  1JL9 A;  2BOH A;  3KK6 A;  2UWP B;  2FLG A;  4JZD L;  2EI6 B;  4RS0 A;  5CKN A;  3FFG L;  2H9E L;  2J4I B;  4D0E A;  3F1S B;  2P3F N;  2W2O E;  1EPG A;  1HZ8 A;  2PHB B;  1EPH A;  1N1I A;  1CVU A;  2BZ6 L;  4Y71 B;  3HS7 A;  1HX2 A;  1IQI L;  1HJ7 A;  1HT5 A;  2RNL A;  1JV2 B;  4BDX A;  4CUE A;  2UWL B;  2EI8 B;  3TBD A;  4JYV L;  4O02 B;  2Y5G L;  2MGR A;  1FAX L;  2KV4 A;  2VWM K;  4Z0L A;  1YUF A;  4TGF A;  1EMO A;  2P3T A;  3EGF A;  2BMG A;  2KB9 A;  2BOU A;  2P26 A;  2PR3 B;  2VJ3 A;  5JBA E;  1APO A;  3OLT A;  1KLO A;  4RRX A;  1HAE A;  2I9B A;  1QFK L;  1IQN L;  2BOK L;  4NGA L;  4OTJ A;  3BT2 A;  3N8X A;  2K2S B;  4O1Z A;  2FZZ L;  1TPG A;  1IQH L;  2WPH E;  5KIR A;  1DDX A;  2WG3 C;  1C5M F;  1IQG L;  3HO4 A;  4X8T L;  2P93 L;  3ZYG A;  2W86 A;  3N8Y B;  1IQJ L;  5JB8 E;  1NPE B;  4NA9 L;  2Y7Z B;  1WHE A;  3N8Y A;  2KNI A;  3SOQ A;  2VVU L;  4Z6A L;  3Q3K B;  1DIY A;  1P9J A;  4D0F A;  4D90 A;  6COX A;  2NPR A;  4JYU L;  4Y79 B;  5FDQ A;  3SOV A;  2MHP A;  3U7U G;  1IGZ A;  1F7M A;  2XC0 L;  4FM5 A;  1WU1 B;  1FAK L;  3F6U L;  1IOX A;  1G1T A;  1NT0 A;  2PUQ L;  5E8D A;  1CQE A;  2VH6 B;  1JBU L;  3LN1 A;  2WYG B;  1ATE A;  4RRW A;  1F0S B;  1U67 A;  2BO2 A;  2YGO A;  1YUG A;  1ADX A;  1BF9 A;  1YO8 A;  3M36 L;  2BQ7 A;  2AYL A;  3BT1 A;  2VH0 B;  4XLW A;  1IQF L;  3TZI A;  4BTT A;  3POY A;  2XC4 L;  4CUD A;  4Y7B B;  3P5B L;  2OYE P;  2RHP A;  5JBC E;  3U73 A;  2JKH L;  2WPM E;  5L2Z L;  1O5D L;  5JVZ A;  2RA0 L;  3GCW E;  2Y38 A;  1FFM A;  1I0U A;  1LPZ A;  1PGE A;  2XBY L;  1AUT L;  2F9B L;  1HAF A;  1P0S L;  3M37 L;  1URK A;  4C16 A;  1EPJ A;  1IQK L;  3FCS B;  1LPG A;  1TLE A;  3KQD L;  3LTG D;  1IJQ A;  3K9X A;  4XBM A;  1DVA L;  2BQW A;  2B7D L;  2FLR L;  3KQC L;  4Y6D B;  2WPK E;  1KLJ L;  2P94 L;  2W2Q E;  4BXW A;  2K2T A;  1HRE A;  2XC5 L;  2DDU A;  1PRH A;  4BTI A;  4JZE L;  3TK5 B;  1UZK A;  4BTU A;  1EAI C;  2M74 A;  3R05 A;  5CKM A;  1U8C B;  1CVW L;  3H5C B;  3GCX E;  4ZH8 B;  2VWN L;  1PXX A;  4ZAE B;  4M10 A;  4RRY A;  3BPS E;  1RFN B;  3C9A C;  5EGM B;  5KN5 C;  1B9W A;  1CCV A;  1K37 A;  3TK6 B;  3CA7 A;  4RUT A;  1L5G B;  5JW1 A;  2UWO B;  1IQL L;  4YT6 L;  2BQ6 A;  3LC5 B;  3NJP C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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