2UWLB

Selective and dual action orally active inhibitors of thrombin and factor xa
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Selective and Dual Action Orally Active Inhibitors of Thrombin and Factor Xa.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords COAGULATION FACTOR X
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00008 EGF EGF-like domain
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2uwlB00
2H9EL 2BOUA 2Y80B 3N8YA 2Y7ZB 2VWLL 2XC5L 4XBMA 2WG4B 4Z6AL 1UZQA 1IQKL 1N1IA 1NPEB 1APOA 1G2LB 3NJPC 3LAQA 4ZHAB 5KN5C 1OB1C 3SOQA 1XKAL 5JBCE 1PRHA 2BMGA 1NFXB 1M1XB 5JVYA 3RR3A 3CFWA 1U67A 2K2TA 3N8ZA 2Y5GL 4COXA 2W2OE 2UWLB 3N8YB 1NZIA 3POYA 1IQJL 4JZFL 3GISX 3TK5B 3U7UG 1EPJA 3LTFB 1JL9A 2Y38A 3LTGD 1KLJL 2EI7B 2W2NE 4NG9L 1EBVA 1DX5I 4ISHL 4BDXA 1G1TA 3TZIA 2XBYL 3HPTA 1FFMA 2BOXA 3HS7A 1DDXA 2P3UA 1EPGA 4OTJA 1ATAA 4JZDL 4NA9L 4XLWA 4MMZB 2PHBB 1DVAL 3KRKA 2RA0L 3C9AC 3KK6A 1COUA 1NFYB 2BQ6A 3U73A 3GCXE 1HREA 3ENSA 3KQDL 4YZUB 1FE2A 2PR3B 1F0RB 3KQBL 4RRWA 1EAIC 4ZXXL 3EGFA 1FAKL 1IQIL 4X8VL 1CQEA 3MDLA 3SOBB 2M74A 3ZYIB 5FDQA 2KL7A 2VWOL 1X7AL 1APQA 4TGFA 1N7DA 4LORA 3KL6B 2BQWA 4M10A 4CSYA 2WFTA 1IQML 2Y5FL 2VWMK 1FAXL 3LN1A 1FJSL 4FM5A 3F1SB 1EMNA 1A3PA 2W3IB 3N8WA 4X8TL 1G1SA 2Q1JB 4X8SL 3HS5A 3ELAL 4O1ZA 1NFUB 4D0FA 2WPIE 2W3KB 1DIYA 2VH6B 1U8CB 3BPSE 3GCWE 1IQLL 2XBWL 4D90A 2VVUL 1L5GB 2WYGB 1IGXA 4X8UL 2W26B 2CJIB 2WYJB 4Y71B 4RRZA 1UZJA 1ATDA 1MQ6L 2EI6B 2BZ6L 3N8WB 4ZAEB 1ATBA 4CUFA 2FD6A 4LMFA 3R05A 2Y7XB 3CA7A 1ZAQA 3CS7L 1EMOA 1IOEL 2XBXL 3IITB 1Z6CA 4ZXYL 1KLIL 1HT8A 1YUGA 2J95B 5F19A 1W7XL 1K36A 1NFWB 2I9BA 1XDTR 2OYEP 2FLBL 1EQGA 2OYUP 2KB9A 1IQEL 4A7IA 1HT5A 4Y7BB 4NGAL 2WPLE 3IJEB 1TPGA 2AYLA 4CUDA 1UZPA 1EZQB 3QCWA 5JW1A 5L2ZL 3LC5B 2GD4A 1C5MF 3NTGA 1AUTL 2XC4L 3HO4A 4ISIL 1KIGL 6COXA 4RRYA 3LC3B 2J38B 4RUTA 2W86A 5CKQA 1K37A 2WFXB 3KCGL 2XC0L 2VH0B 2RNLA 4AQTA 4RRXA 1P9JA 2VJ3A 3QMOA 1EQHA 3HS6A 4YT7L 5JB8E 1IP0A 4Y79B 1CVWL 1V3XB 2PUQL 1B9WA 3MQEA 2Y5HL 2KV4A 3SW2A 5JVZA 3QH0A 1PTHA 3ASIA 3Q7DA 5EGMB 1ATEA 5KIRA 1CX2A 1RFNB 5L2YL 2NPRA 1YUFA 2WPME 2XBVL 1EPHA 1P0SL 2J34B 2YGOA 2MGPA 4BDWA 1YUKB 1UZKA 1GK5A 1HX2A 2P93L 3HO5A 1YO8A 5CKMA 2K2SB 2B7DL 5L30L 1HAFA 5K0HB 5IKTA 3KQCL 4Y7AB 5IKQA 4ZH8B 3KQEL 2MGRA 1IJQA 5IKRA 2W2PE 3LIWB 5JBAE 3SOVA 5JBBE 3ZYGA 2BO2A 2I9AA 1HRFA 4C16A 1Z6EL 3TH3L 2TGFA 3Q3KB 4BTUA 3CENL 5IKVA 3BT1A 1EPIA 2D1JB 3ZYJB 3P5BL 4JYVL 1G2MB 3NT1A 4JYUL 5F1AA 1LMJA 2G00L 2BOKL 3V65B 2P3FL 2YGPA 2WPJE 1I0UA 4Y76B 3M37L 4PH9A 2UWPB 1HJ7A 1G1QA 2Y82B 2EI8B 1HZ8A 1IQNL 1MOXC 1IVOC 3N8XA 1W8BL 2WPHE 2RHPA 2P95L 4BTIA 3K9XA 1PGEA 1CEJA 3LN0A 4E1GA 3TBDA 1EGFA 4BTTA 3OLUA 4MMXB 3FFGL 3TGFA 2W2ME 4Y6DB 4BXSA 1LPGA 1J9CL 4MMYB 1LPKA 4RS0A 1QFKL 1IQFL 2J2UB 1G1RA 4Z0KB 1YGCL 5CISA 2P3TA 1JBUL 2P26A 3N8VA 1IQGL 1NT0A 1F7MA 1LQDA 4JZEL 1IQHL 1Q4GA 1HAEA 1TOZA 2FZZL 2VVCK 1JV2B 1NQLB 2P94L 1PFXL 1XKBA 4XL1A 3V64C 3HO3A 1PXXA 2FLRL 4CUEA 5JB9E 2F9BL 1WHEA 2MHPA 2P16L 3BT2A 4O02B 1CVUA 2Y81B 1WU1B 3DEMA 1KLOA 1HCGB 2WPKE 2J94B 1SZBA 1ADXA 3OLTA 1XFEA 2BQ7A 3FCSB 1CCVA 1IGZA 3F6UL 2UWOB 2ADXA 4M11A 1MQ5L 1FF7A 4Z0LA 4YT6L 1DQBA 1L3YA 1TLEA 1KSNB 4D0EA 1IOXA 3M36L 2FLGA 2VVVL 5E8DA 5CKNA 3PGHA 5COXA 1F7EA 2P28B 2VWNL 2WG3C 5I46L 1URKA 4BXWA 2DDUA 2W2QE 3NTBA 1CCFA 2J4IB 4G1MB 3TK6B 2BOHA 1F0SB 2P3FN 1WHFA 1BF9A 3FBYA 4OTYA 1LPZA 1O5DL 3H5CB 2JKHL 1FSBA
chains in the Genus database with same CATH superfamily
2H9EL 2BOUA 2Y80B 3N8YA 2Y7ZB 2VWLL 2XC5L 4XBMA 2WG4B 4Z6AL 1UZQA 3S6XA 1IQKL 1N1IA 1NPEB 4GU3A 1APOA 1G2LB 3NJPC 3LAQA 4ZHAB 5KN5C 1OB1C 3SOQA 1XKAL 5JBCE 1PRHA 2BMGA 1NFXB 1M1XB 5JVYA 3RR3A 3CFWA 2HORA 4A94C 1U67A 2K2TA 3N8ZA 2Y5GL 4COXA 2W2OE 2UWLB 3N8YB 1NZIA 3POYA 1IQJL 4JZFL 3GISX 3TK5B 3U7UG 1EPJA 3LTFB 1JL9A 2Y38A 3LTGD 1KLJL 2EI7B 2W2NE 4NG9L 1EBVA 1DX5I 4ISHL 4BDXA 1G1TA 3TZIA 2XBYL 3HPTA 1FFMA 2BOXA 3HS7A 1DDXA 2P3UA 1EPGA 4OTJA 1ATAA 4JZDL 4NA9L 4XLWA 4MMZB 2PHBB 1DVAL 3KRKA 2RA0L 3C9AC 3KK6A 1COUA 1NFYB 2BQ6A 3U73A 3GCXE 1HREA 3ENSA 3KQDL 4YZUB 1FE2A 2PR3B 1F0RB 3KQBL 4RRWA 2BSFA 1EAIC 4ZXXL 3EGFA 1FAKL 1IQIL 4X8VL 1CQEA 3MDLA 3SOBB 2M74A 2VRSA 3ZYIB 2HOXA 5FDQA 2KL7A 2VWOL 1X7AL 1APQA 4TGFA 1N7DA 4LORA 3KL6B 2BQWA 4M10A 4CSYA 2WFTA 1IQML 2Y5FL 2VWMK 1FAXL 3LN1A 1FJSL 4FM5A 3F1SB 1EMNA 1A3PA 2W3IB 3N8WA 4X8TL 1G1SA 2Q1JB 4X8SL 3HS5A 3ELAL 4O1ZA 1NFUB 4D0FA 2WPIE 2W3KB 1DIYA 2VH6B 1U8CB 3BPSE 3GCWE 1LMMA 1IQLL 2XBWL 2BT7A 4D90A 2VVUL 1L5GB 2WYGB 1IGXA 4X8UL 2W26B 2CJIB 2WYJB 4Y71B 4RRZA 1UZJA 1ATDA 1MQ6L 2EI6B 2BZ6L 3N8WB 4ZAEB 1ATBA 4CUFA 2FD6A 4LMFA 3R05A 2Y7XB 3CA7A 1ZAQA 2KNIA 3CS7L 1EMOA 1IOEL 1KKEA 2XBXL 3IITB 1Z6CA 2H9EC 4ZXYL 1KLIL 1HT8A 1LK9A 1YUGA 2J95B 5F19A 1W7XL 1K36A 1NFWB 2I9BA 1XDTR 2OYEP 2FLBL 1EQGA 2OYUP 2KB9A 1IQEL 4A7IA 1HT5A 4Y7BB 4NGAL 2WPLE 3IJEB 1TPGA 2AYLA 4CUDA 1UZPA 1EZQB 3QCWA 5JW1A 5L2ZL 3LC5B 2GD4A 1C5MF 3NTGA 1AUTL 2XC4L 3HO4A 4ISIL 1KIGL 6COXA 4RRYA 3LC3B 2J38B 4RUTA 2W86A 5CKQA 1K37A 2WZPP 2WFXB 3KCGL 2XC0L 2VH0B 1V1HA 2RNLA 4AQTA 4RRXA 1P9JA 2VJ3A 3QMOA 1EQHA 3HS6A 4YT7L 5JB8E 1IP0A 4Y79B 1CVWL 1V3XB 2PUQL 1B9WA 3MQEA 2Y5HL 2KV4A 3SW2A 5JVZA 3QH0A 1PTHA 3ASIA 3Q7DA 5EGMB 1ATEA 5KIRA 1CX2A 1RFNB 5L2YL 2NPRA 1YUFA 2WPME 2XBVL 1EPHA 1P0SL 2J34B 2YGOA 2MGPA 4BDWA 1YUKB 1UZKA 1GK5A 1HX2A 2P93L 3HO5A 1YO8A 5CKMA 2K2SB 2B7DL 5L30L 1HAFA 5K0HB 5IKTA 3KQCL 4Y7AB 5IKQA 4ZH8B 3KQEL 2MGRA 1IJQA 5IKRA 2W2PE 3LIWB 5JBAE 3SOVA 5JBBE 3ZYGA 2BO2A 2I9AA 1HRFA 4C16A 1Z6EL 3TH3L 2TGFA 3Q3KB 4BTUA 3CENL 5IKVA 3BT1A 1EPIA 2D1JB 3ZYJB 3P5BL 4JYVL 1G2MB 3NT1A 4JYUL 5F1AA 1LMJA 2G00L 2BOKL 3V65B 2P3FL 2YGPA 2WPJE 1I0UA 4Y76B 3M37L 4PH9A 2UWPB 1HJ7A 1G1QA 2YGQA 2Y82B 2EI8B 1HZ8A 1IQNL 1MOXC 1IVOC 3N8XA 1W8BL 2WPHE 2RHPA 2P95L 4BTIA 3K9XA 1PGEA 1CEJA 3LN0A 4E1GA 3TBDA 1EGFA 4BTTA 3OLUA 4MMXB 3FFGL 2BT8A 3TGFA 2W2ME 4Y6DB 4BXSA 1LPGA 1J9CL 4MMYB 1LPKA 4RS0A 1QFKL 1IQFL 2J2UB 1G1RA 4Z0KB 1YGCL 5CISA 2P3TA 2JJLA 1JBUL 2P26A 3N8VA 1IQGL 1NT0A 1F7MA 1LQDA 4JZEL 1IQHL 1Q4GA 1QIUA 1HAEA 1TOZA 2FZZL 2VVCK 1JV2B 1NQLB 2P94L 1PFXL 1XKBA 4XL1A 3V64C 1V1IA 3HO3A 1PXXA 2FLRL 4CUEA 5JB9E 2F9BL 1WHEA 2MHPA 2P16L 3BT2A 4O02B 1CVUA 2Y81B 1WU1B 3DEMA 1KLOA 1HCGB 2WPKE 2J94B 1SZBA 1ADXA 3OLTA 1XFEA 2BQ7A 3FCSB 1CCVA 1IGZA 3F6UL 2UWOB 2ADXA 4M11A 1MQ5L 1FF7A 4Z0LA 4YT6L 1DQBA 1L3YA 1TLEA 1KSNB 4D0EA 1IOXA 3M36L 2FLGA 2VVVL 5E8DA 5CKNA 3PGHA 5COXA 1F7EA 2P28B 2VWNL 2WG3C 4GU4A 5I46L 1URKA 4BXWA 2DDUA 2W2QE 3NTBA 1CCFA 2J4IB 4G1MB 3TK6B 2BOHA 1F0SB 2P3FN 1WHFA 1BF9A 3FBYA 4OTYA 1LPZA 1O5DL 3H5CB 2JKHL 1FSBA
chains in the Genus database with same CATH topology
2H9EL 2BOUA 2Y80B 3N8YA 2Y7ZB 2VWLL 2XC5L 4XBMA 2WG4B 4Z6AL 1UZQA 3S6XA 1IQKL 1N1IA 1NPEB 1APOA 1G2LB 3NJPC 3LAQA 4ZHAB 5KN5C 1OB1C 3SOQA 1XKAL 5JBCE 1PRHA 2BMGA 1NFXB 1M1XB 5JVYA 3RR3A 3CFWA 4A94C 1U67A 2K2TA 3N8ZA 2Y5GL 4COXA 2W2OE 2UWLB 3N8YB 1NZIA 3POYA 1IQJL 4JZFL 3GISX 3TK5B 3U7UG 1EPJA 3LTFB 1JL9A 2Y38A 3LTGD 1KLJL 2EI7B 2W2NE 4NG9L 1EBVA 1DX5I 4ISHL 4BDXA 1G1TA 3TZIA 2XBYL 3HPTA 1FFMA 2BOXA 3HS7A 1DDXA 2P3UA 1EPGA 4OTJA 1ATAA 4JZDL 4NA9L 4XLWA 4MMZB 2PHBB 1DVAL 3KRKA 2RA0L 3C9AC 3KK6A 1COUA 1NFYB 2BQ6A 3U73A 3GCXE 1HREA 3ENSA 3KQDL 4YZUB 1FE2A 2PR3B 1F0RB 3KQBL 4RRWA 1EAIC 4ZXXL 3EGFA 1FAKL 1IQIL 4X8VL 1CQEA 3MDLA 3SOBB 2M74A 3ZYIB 5FDQA 2KL7A 2VWOL 1X7AL 1APQA 4TGFA 1N7DA 4LORA 3KL6B 2BQWA 4M10A 4CSYA 2WFTA 1IQML 2Y5FL 2VWMK 1FAXL 3LN1A 1FJSL 4FM5A 3F1SB 1EMNA 1A3PA 2W3IB 3N8WA 4X8TL 1G1SA 2Q1JB 4X8SL 3HS5A 3ELAL 4O1ZA 1NFUB 4D0FA 2WPIE 2W3KB 1DIYA 2VH6B 1U8CB 3BPSE 3GCWE 1LMMA 1IQLL 2XBWL 4D90A 2VVUL 1L5GB 2WYGB 1IGXA 4X8UL 2W26B 2CJIB 2WYJB 4Y71B 4RRZA 1UZJA 1ATDA 1MQ6L 2EI6B 2BZ6L 3N8WB 4ZAEB 1ATBA 4CUFA 2FD6A 4LMFA 3R05A 2Y7XB 3CA7A 1ZAQA 2KNIA 3CS7L 1EMOA 1IOEL 2XBXL 3IITB 1Z6CA 2H9EC 4ZXYL 1KLIL 1HT8A 1YUGA 2J95B 5F19A 1W7XL 1K36A 1NFWB 2I9BA 1XDTR 2OYEP 2FLBL 1EQGA 2OYUP 2KB9A 1IQEL 4A7IA 1HT5A 4Y7BB 4NGAL 2WPLE 3IJEB 1TPGA 2AYLA 4CUDA 1UZPA 1EZQB 3QCWA 5JW1A 5L2ZL 3LC5B 2GD4A 1C5MF 3NTGA 1AUTL 2XC4L 3HO4A 4ISIL 1KIGL 6COXA 4RRYA 3LC3B 2J38B 4RUTA 2W86A 5CKQA 1K37A 2WZPP 2WFXB 3KCGL 2XC0L 2VH0B 2RNLA 4AQTA 4RRXA 1P9JA 2VJ3A 3QMOA 1EQHA 3HS6A 4YT7L 5JB8E 1IP0A 4Y79B 1CVWL 1V3XB 2PUQL 1B9WA 3MQEA 2Y5HL 2KV4A 3SW2A 5JVZA 3QH0A 1PTHA 3ASIA 3Q7DA 5EGMB 1ATEA 5KIRA 1CX2A 1RFNB 5L2YL 2NPRA 1YUFA 2WPME 2XBVL 1EPHA 1P0SL 2J34B 2YGOA 2MGPA 4BDWA 1YUKB 1UZKA 1GK5A 1HX2A 2P93L 3HO5A 1YO8A 5CKMA 2K2SB 2B7DL 5L30L 1HAFA 5K0HB 5IKTA 3KQCL 4Y7AB 5IKQA 4ZH8B 3KQEL 2MGRA 1IJQA 5IKRA 2W2PE 3LIWB 5JBAE 3SOVA 5JBBE 3ZYGA 2BO2A 2I9AA 1HRFA 4C16A 1Z6EL 3TH3L 2TGFA 3Q3KB 4BTUA 3CENL 5IKVA 3BT1A 1EPIA 2D1JB 3ZYJB 3P5BL 4JYVL 1G2MB 3NT1A 4JYUL 5F1AA 1LMJA 2G00L 2BOKL 3V65B 2P3FL 2YGPA 2WPJE 1I0UA 4Y76B 3M37L 4PH9A 2UWPB 1HJ7A 1G1QA 2YGQA 2Y82B 2EI8B 1HZ8A 1IQNL 1MOXC 1IVOC 3N8XA 1W8BL 2WPHE 2RHPA 2P95L 4BTIA 3K9XA 1PGEA 1CEJA 3LN0A 4E1GA 3TBDA 1EGFA 4BTTA 3OLUA 4MMXB 3FFGL 3TGFA 2W2ME 4Y6DB 4BXSA 1LPGA 1J9CL 4MMYB 1LPKA 4RS0A 1QFKL 1IQFL 2J2UB 1G1RA 4Z0KB 1YGCL 5CISA 2P3TA 1JBUL 2P26A 3N8VA 1IQGL 1NT0A 1F7MA 1LQDA 4JZEL 1IQHL 1Q4GA 1HAEA 1TOZA 2FZZL 2VVCK 1JV2B 1NQLB 2P94L 1PFXL 1XKBA 4XL1A 3V64C 3HO3A 1PXXA 2FLRL 4CUEA 5JB9E 2F9BL 1WHEA 2MHPA 2P16L 3BT2A 4O02B 1CVUA 2Y81B 1WU1B 3DEMA 1KLOA 1HCGB 2WPKE 2J94B 1SZBA 1ADXA 3OLTA 1XFEA 2BQ7A 3FCSB 1CCVA 1IGZA 3F6UL 2UWOB 2ADXA 4M11A 1MQ5L 1FF7A 4Z0LA 4YT6L 1DQBA 1L3YA 1TLEA 1KSNB 4D0EA 1IOXA 3M36L 2FLGA 2VVVL 5E8DA 5CKNA 3PGHA 5COXA 1F7EA 2P28B 2VWNL 2WG3C 5I46L 1URKA 4BXWA 2DDUA 2W2QE 3NTBA 1CCFA 2J4IB 4G1MB 3TK6B 2BOHA 1F0SB 2P3FN 1WHFA 1BF9A 3FBYA 4OTYA 1LPZA 1O5DL 3H5CB 2JKHL 1FSBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H9E L;  2BOU A;  2Y80 B;  3N8Y A;  2Y7Z B;  2VWL L;  2XC5 L;  4XBM A;  2WG4 B;  4Z6A L;  1UZQ A;  1IQK L;  1N1I A;  1NPE B;  1APO A;  1G2L B;  3NJP C;  3LAQ A;  4ZHA B;  5KN5 C;  1OB1 C;  3SOQ A;  1XKA L;  5JBC E;  1PRH A;  2BMG A;  1NFX B;  1M1X B;  5JVY A;  3RR3 A;  3CFW A;  1U67 A;  2K2T A;  3N8Z A;  2Y5G L;  4COX A;  2W2O E;  2UWL B;  3N8Y B;  1NZI A;  3POY A;  1IQJ L;  4JZF L;  3GIS X;  3TK5 B;  3U7U G;  1EPJ A;  3LTF B;  1JL9 A;  2Y38 A;  3LTG D;  1KLJ L;  2EI7 B;  2W2N E;  4NG9 L;  1EBV A;  1DX5 I;  4ISH L;  4BDX A;  1G1T A;  3TZI A;  2XBY L;  3HPT A;  1FFM A;  2BOX A;  3HS7 A;  1DDX A;  2P3U A;  1EPG A;  4OTJ A;  1ATA A;  4JZD L;  4NA9 L;  4XLW A;  4MMZ B;  2PHB B;  1DVA L;  3KRK A;  2RA0 L;  3C9A C;  3KK6 A;  1COU A;  1NFY B;  2BQ6 A;  3U73 A;  3GCX E;  1HRE A;  3ENS A;  3KQD L;  4YZU B;  1FE2 A;  2PR3 B;  1F0R B;  3KQB L;  4RRW A;  1EAI C;  4ZXX L;  3EGF A;  1FAK L;  1IQI L;  4X8V L;  1CQE A;  3MDL A;  3SOB B;  2M74 A;  3ZYI B;  5FDQ A;  2KL7 A;  2VWO L;  1X7A L;  1APQ A;  4TGF A;  1N7D A;  4LOR A;  3KL6 B;  2BQW A;  4M10 A;  4CSY A;  2WFT A;  1IQM L;  2Y5F L;  2VWM K;  1FAX L;  3LN1 A;  1FJS L;  4FM5 A;  3F1S B;  1EMN A;  1A3P A;  2W3I B;  3N8W A;  4X8T L;  1G1S A;  2Q1J B;  4X8S L;  3HS5 A;  3ELA L;  4O1Z A;  1NFU B;  4D0F A;  2WPI E;  2W3K B;  1DIY A;  2VH6 B;  1U8C B;  3BPS E;  3GCW E;  1IQL L;  2XBW L;  4D90 A;  2VVU L;  1L5G B;  2WYG B;  1IGX A;  4X8U L;  2W26 B;  2CJI B;  2WYJ B;  4Y71 B;  4RRZ A;  1UZJ A;  1ATD A;  1MQ6 L;  2EI6 B;  2BZ6 L;  3N8W B;  4ZAE B;  1ATB A;  4CUF A;  2FD6 A;  4LMF A;  3R05 A;  2Y7X B;  3CA7 A;  1ZAQ A;  3CS7 L;  1EMO A;  1IOE L;  2XBX L;  3IIT B;  1Z6C A;  4ZXY L;  1KLI L;  1HT8 A;  1YUG A;  2J95 B;  5F19 A;  1W7X L;  1K36 A;  1NFW B;  2I9B A;  1XDT R;  2OYE P;  2FLB L;  1EQG A;  2OYU P;  2KB9 A;  1IQE L;  4A7I A;  1HT5 A;  4Y7B B;  4NGA L;  2WPL E;  3IJE B;  1TPG A;  2AYL A;  4CUD A;  1UZP A;  1EZQ B;  3QCW A;  5JW1 A;  5L2Z L;  3LC5 B;  2GD4 A;  1C5M F;  3NTG A;  1AUT L;  2XC4 L;  3HO4 A;  4ISI L;  1KIG L;  6COX A;  4RRY A;  3LC3 B;  2J38 B;  4RUT A;  2W86 A;  5CKQ A;  1K37 A;  2WFX B;  3KCG L;  2XC0 L;  2VH0 B;  2RNL A;  4AQT A;  4RRX A;  1P9J A;  2VJ3 A;  3QMO A;  1EQH A;  3HS6 A;  4YT7 L;  5JB8 E;  1IP0 A;  4Y79 B;  1CVW L;  1V3X B;  2PUQ L;  1B9W A;  3MQE A;  2Y5H L;  2KV4 A;  3SW2 A;  5JVZ A;  3QH0 A;  1PTH A;  3ASI A;  3Q7D A;  5EGM B;  1ATE A;  5KIR A;  1CX2 A;  1RFN B;  5L2Y L;  2NPR A;  1YUF A;  2WPM E;  2XBV L;  1EPH A;  1P0S L;  2J34 B;  2YGO A;  2MGP A;  4BDW A;  1YUK B;  1UZK A;  1GK5 A;  1HX2 A;  2P93 L;  3HO5 A;  1YO8 A;  5CKM A;  2K2S B;  2B7D L;  5L30 L;  1HAF A;  5K0H B;  5IKT A;  3KQC L;  4Y7A B;  5IKQ A;  4ZH8 B;  3KQE L;  2MGR A;  1IJQ A;  5IKR A;  2W2P E;  3LIW B;  5JBA E;  3SOV A;  5JBB E;  3ZYG A;  2BO2 A;  2I9A A;  1HRF A;  4C16 A;  1Z6E L;  3TH3 L;  2TGF A;  3Q3K B;  4BTU A;  3CEN L;  5IKV A;  3BT1 A;  1EPI A;  2D1J B;  3ZYJ B;  3P5B L;  4JYV L;  1G2M B;  3NT1 A;  4JYU L;  5F1A A;  1LMJ A;  2G00 L;  2BOK L;  3V65 B;  2P3F L;  2YGP A;  2WPJ E;  1I0U A;  4Y76 B;  3M37 L;  4PH9 A;  2UWP B;  1HJ7 A;  1G1Q A;  2Y82 B;  2EI8 B;  1HZ8 A;  1IQN L;  1MOX C;  1IVO C;  3N8X A;  1W8B L;  2WPH E;  2RHP A;  2P95 L;  4BTI A;  3K9X A;  1PGE A;  1CEJ A;  3LN0 A;  4E1G A;  3TBD A;  1EGF A;  4BTT A;  3OLU A;  4MMX B;  3FFG L;  3TGF A;  2W2M E;  4Y6D B;  4BXS A;  1LPG A;  1J9C L;  4MMY B;  1LPK A;  4RS0 A;  1QFK L;  1IQF L;  2J2U B;  1G1R A;  4Z0K B;  1YGC L;  5CIS A;  2P3T A;  1JBU L;  2P26 A;  3N8V A;  1IQG L;  1NT0 A;  1F7M A;  1LQD A;  4JZE L;  1IQH L;  1Q4G A;  1HAE A;  1TOZ A;  2FZZ L;  2VVC K;  1JV2 B;  1NQL B;  2P94 L;  1PFX L;  1XKB A;  4XL1 A;  3V64 C;  3HO3 A;  1PXX A;  2FLR L;  4CUE A;  5JB9 E;  2F9B L;  1WHE A;  2MHP A;  2P16 L;  3BT2 A;  4O02 B;  1CVU A;  2Y81 B;  1WU1 B;  3DEM A;  1KLO A;  1HCG B;  2WPK E;  2J94 B;  1SZB A;  1ADX A;  3OLT A;  1XFE A;  2BQ7 A;  3FCS B;  1CCV A;  1IGZ A;  3F6U L;  2UWO B;  2ADX A;  4M11 A;  1MQ5 L;  1FF7 A;  4Z0L A;  4YT6 L;  1DQB A;  1L3Y A;  1TLE A;  1KSN B;  4D0E A;  1IOX A;  3M36 L;  2FLG A;  2VVV L;  5E8D A;  5CKN A;  3PGH A;  5COX A;  1F7E A;  2P28 B;  2VWN L;  2WG3 C;  5I46 L;  1URK A;  4BXW A;  2DDU A;  2W2Q E;  3NTB A;  1CCF A;  2J4I B;  4G1M B;  3TK6 B;  2BOH A;  1F0S B;  2P3F N;  1WHF A;  1BF9 A;  3FBY A;  4OTY A;  1LPZ A;  1O5D L;  3H5C B;  2JKH L;  1FSB A; 
#chains in the Genus database with same CATH topology
 2H9E L;  2BOU A;  2Y80 B;  3N8Y A;  2Y7Z B;  2VWL L;  2XC5 L;  4XBM A;  2WG4 B;  4Z6A L;  1UZQ A;  3S6X A;  1IQK L;  1N1I A;  1NPE B;  4GU3 A;  1APO A;  1G2L B;  3NJP C;  3LAQ A;  4ZHA B;  5KN5 C;  1OB1 C;  3SOQ A;  1XKA L;  5JBC E;  1PRH A;  2BMG A;  1NFX B;  1M1X B;  5JVY A;  3RR3 A;  3CFW A;  2HOR A;  4A94 C;  1U67 A;  2K2T A;  3N8Z A;  2Y5G L;  4COX A;  2W2O E;  2UWL B;  3N8Y B;  1NZI A;  3POY A;  1IQJ L;  4JZF L;  3GIS X;  3TK5 B;  3U7U G;  1EPJ A;  3LTF B;  1JL9 A;  2Y38 A;  3LTG D;  1KLJ L;  2EI7 B;  2W2N E;  4NG9 L;  1EBV A;  1DX5 I;  4ISH L;  4BDX A;  1G1T A;  3TZI A;  2XBY L;  3HPT A;  1FFM A;  2BOX A;  3HS7 A;  1DDX A;  2P3U A;  1EPG A;  4OTJ A;  1ATA A;  4JZD L;  4NA9 L;  4XLW A;  4MMZ B;  2PHB B;  1DVA L;  3KRK A;  2RA0 L;  3C9A C;  3KK6 A;  1COU A;  1NFY B;  2BQ6 A;  3U73 A;  3GCX E;  1HRE A;  3ENS A;  3KQD L;  4YZU B;  1FE2 A;  2PR3 B;  1F0R B;  3KQB L;  4RRW A;  2BSF A;  1EAI C;  4ZXX L;  3EGF A;  1FAK L;  1IQI L;  4X8V L;  1CQE A;  3MDL A;  3SOB B;  2M74 A;  2VRS A;  3ZYI B;  2HOX A;  5FDQ A;  2KL7 A;  2VWO L;  1X7A L;  1APQ A;  4TGF A;  1N7D A;  4LOR A;  3KL6 B;  2BQW A;  4M10 A;  4CSY A;  2WFT A;  1IQM L;  2Y5F L;  2VWM K;  1FAX L;  3LN1 A;  1FJS L;  4FM5 A;  3F1S B;  1EMN A;  1A3P A;  2W3I B;  3N8W A;  4X8T L;  1G1S A;  2Q1J B;  4X8S L;  3HS5 A;  3ELA L;  4O1Z A;  1NFU B;  4D0F A;  2WPI E;  2W3K B;  1DIY A;  2VH6 B;  1U8C B;  3BPS E;  3GCW E;  1LMM A;  1IQL L;  2XBW L;  2BT7 A;  4D90 A;  2VVU L;  1L5G B;  2WYG B;  1IGX A;  4X8U L;  2W26 B;  2CJI B;  2WYJ B;  4Y71 B;  4RRZ A;  1UZJ A;  1ATD A;  1MQ6 L;  2EI6 B;  2BZ6 L;  3N8W B;  4ZAE B;  1ATB A;  4CUF A;  2FD6 A;  4LMF A;  3R05 A;  2Y7X B;  3CA7 A;  1ZAQ A;  2KNI A;  3CS7 L;  1EMO A;  1IOE L;  1KKE A;  2XBX L;  3IIT B;  1Z6C A;  2H9E C;  4ZXY L;  1KLI L;  1HT8 A;  1LK9 A;  1YUG A;  2J95 B;  5F19 A;  1W7X L;  1K36 A;  1NFW B;  2I9B A;  1XDT R;  2OYE P;  2FLB L;  1EQG A;  2OYU P;  2KB9 A;  1IQE L;  4A7I A;  1HT5 A;  4Y7B B;  4NGA L;  2WPL E;  3IJE B;  1TPG A;  2AYL A;  4CUD A;  1UZP A;  1EZQ B;  3QCW A;  5JW1 A;  5L2Z L;  3LC5 B;  2GD4 A;  1C5M F;  3NTG A;  1AUT L;  2XC4 L;  3HO4 A;  4ISI L;  1KIG L;  6COX A;  4RRY A;  3LC3 B;  2J38 B;  4RUT A;  2W86 A;  5CKQ A;  1K37 A;  2WZP P;  2WFX B;  3KCG L;  2XC0 L;  2VH0 B;  1V1H A;  2RNL A;  4AQT A;  4RRX A;  1P9J A;  2VJ3 A;  3QMO A;  1EQH A;  3HS6 A;  4YT7 L;  5JB8 E;  1IP0 A;  4Y79 B;  1CVW L;  1V3X B;  2PUQ L;  1B9W A;  3MQE A;  2Y5H L;  2KV4 A;  3SW2 A;  5JVZ A;  3QH0 A;  1PTH A;  3ASI A;  3Q7D A;  5EGM B;  1ATE A;  5KIR A;  1CX2 A;  1RFN B;  5L2Y L;  2NPR A;  1YUF A;  2WPM E;  2XBV L;  1EPH A;  1P0S L;  2J34 B;  2YGO A;  2MGP A;  4BDW A;  1YUK B;  1UZK A;  1GK5 A;  1HX2 A;  2P93 L;  3HO5 A;  1YO8 A;  5CKM A;  2K2S B;  2B7D L;  5L30 L;  1HAF A;  5K0H B;  5IKT A;  3KQC L;  4Y7A B;  5IKQ A;  4ZH8 B;  3KQE L;  2MGR A;  1IJQ A;  5IKR A;  2W2P E;  3LIW B;  5JBA E;  3SOV A;  5JBB E;  3ZYG A;  2BO2 A;  2I9A A;  1HRF A;  4C16 A;  1Z6E L;  3TH3 L;  2TGF A;  3Q3K B;  4BTU A;  3CEN L;  5IKV A;  3BT1 A;  1EPI A;  2D1J B;  3ZYJ B;  3P5B L;  4JYV L;  1G2M B;  3NT1 A;  4JYU L;  5F1A A;  1LMJ A;  2G00 L;  2BOK L;  3V65 B;  2P3F L;  2YGP A;  2WPJ E;  1I0U A;  4Y76 B;  3M37 L;  4PH9 A;  2UWP B;  1HJ7 A;  1G1Q A;  2YGQ A;  2Y82 B;  2EI8 B;  1HZ8 A;  1IQN L;  1MOX C;  1IVO C;  3N8X A;  1W8B L;  2WPH E;  2RHP A;  2P95 L;  4BTI A;  3K9X A;  1PGE A;  1CEJ A;  3LN0 A;  4E1G A;  3TBD A;  1EGF A;  4BTT A;  3OLU A;  4MMX B;  3FFG L;  2BT8 A;  3TGF A;  2W2M E;  4Y6D B;  4BXS A;  1LPG A;  1J9C L;  4MMY B;  1LPK A;  4RS0 A;  1QFK L;  1IQF L;  2J2U B;  1G1R A;  4Z0K B;  1YGC L;  5CIS A;  2P3T A;  2JJL A;  1JBU L;  2P26 A;  3N8V A;  1IQG L;  1NT0 A;  1F7M A;  1LQD A;  4JZE L;  1IQH L;  1Q4G A;  1QIU A;  1HAE A;  1TOZ A;  2FZZ L;  2VVC K;  1JV2 B;  1NQL B;  2P94 L;  1PFX L;  1XKB A;  4XL1 A;  3V64 C;  1V1I A;  3HO3 A;  1PXX A;  2FLR L;  4CUE A;  5JB9 E;  2F9B L;  1WHE A;  2MHP A;  2P16 L;  3BT2 A;  4O02 B;  1CVU A;  2Y81 B;  1WU1 B;  3DEM A;  1KLO A;  1HCG B;  2WPK E;  2J94 B;  1SZB A;  1ADX A;  3OLT A;  1XFE A;  2BQ7 A;  3FCS B;  1CCV A;  1IGZ A;  3F6U L;  2UWO B;  2ADX A;  4M11 A;  1MQ5 L;  1FF7 A;  4Z0L A;  4YT6 L;  1DQB A;  1L3Y A;  1TLE A;  1KSN B;  4D0E A;  1IOX A;  3M36 L;  2FLG A;  2VVV L;  5E8D A;  5CKN A;  3PGH A;  5COX A;  1F7E A;  2P28 B;  2VWN L;  2WG3 C;  4GU4 A;  5I46 L;  1URK A;  4BXW A;  2DDU A;  2W2Q E;  3NTB A;  1CCF A;  2J4I B;  4G1M B;  3TK6 B;  2BOH A;  1F0S B;  2P3F N;  1WHF A;  1BF9 A;  3FBY A;  4OTY A;  1LPZ A;  1O5D L;  3H5C B;  2JKH L;  1FSB A; 
#chains in the Genus database with same CATH homology
 2H9E L;  2BOU A;  2Y80 B;  3N8Y A;  2Y7Z B;  2VWL L;  2XC5 L;  4XBM A;  2WG4 B;  4Z6A L;  1UZQ A;  3S6X A;  1IQK L;  1N1I A;  1NPE B;  1APO A;  1G2L B;  3NJP C;  3LAQ A;  4ZHA B;  5KN5 C;  1OB1 C;  3SOQ A;  1XKA L;  5JBC E;  1PRH A;  2BMG A;  1NFX B;  1M1X B;  5JVY A;  3RR3 A;  3CFW A;  4A94 C;  1U67 A;  2K2T A;  3N8Z A;  2Y5G L;  4COX A;  2W2O E;  2UWL B;  3N8Y B;  1NZI A;  3POY A;  1IQJ L;  4JZF L;  3GIS X;  3TK5 B;  3U7U G;  1EPJ A;  3LTF B;  1JL9 A;  2Y38 A;  3LTG D;  1KLJ L;  2EI7 B;  2W2N E;  4NG9 L;  1EBV A;  1DX5 I;  4ISH L;  4BDX A;  1G1T A;  3TZI A;  2XBY L;  3HPT A;  1FFM A;  2BOX A;  3HS7 A;  1DDX A;  2P3U A;  1EPG A;  4OTJ A;  1ATA A;  4JZD L;  4NA9 L;  4XLW A;  4MMZ B;  2PHB B;  1DVA L;  3KRK A;  2RA0 L;  3C9A C;  3KK6 A;  1COU A;  1NFY B;  2BQ6 A;  3U73 A;  3GCX E;  1HRE A;  3ENS A;  3KQD L;  4YZU B;  1FE2 A;  2PR3 B;  1F0R B;  3KQB L;  4RRW A;  1EAI C;  4ZXX L;  3EGF A;  1FAK L;  1IQI L;  4X8V L;  1CQE A;  3MDL A;  3SOB B;  2M74 A;  3ZYI B;  5FDQ A;  2KL7 A;  2VWO L;  1X7A L;  1APQ A;  4TGF A;  1N7D A;  4LOR A;  3KL6 B;  2BQW A;  4M10 A;  4CSY A;  2WFT A;  1IQM L;  2Y5F L;  2VWM K;  1FAX L;  3LN1 A;  1FJS L;  4FM5 A;  3F1S B;  1EMN A;  1A3P A;  2W3I B;  3N8W A;  4X8T L;  1G1S A;  2Q1J B;  4X8S L;  3HS5 A;  3ELA L;  4O1Z A;  1NFU B;  4D0F A;  2WPI E;  2W3K B;  1DIY A;  2VH6 B;  1U8C B;  3BPS E;  3GCW E;  1LMM A;  1IQL L;  2XBW L;  4D90 A;  2VVU L;  1L5G B;  2WYG B;  1IGX A;  4X8U L;  2W26 B;  2CJI B;  2WYJ B;  4Y71 B;  4RRZ A;  1UZJ A;  1ATD A;  1MQ6 L;  2EI6 B;  2BZ6 L;  3N8W B;  4ZAE B;  1ATB A;  4CUF A;  2FD6 A;  4LMF A;  3R05 A;  2Y7X B;  3CA7 A;  1ZAQ A;  2KNI A;  3CS7 L;  1EMO A;  1IOE L;  2XBX L;  3IIT B;  1Z6C A;  2H9E C;  4ZXY L;  1KLI L;  1HT8 A;  1YUG A;  2J95 B;  5F19 A;  1W7X L;  1K36 A;  1NFW B;  2I9B A;  1XDT R;  2OYE P;  2FLB L;  1EQG A;  2OYU P;  2KB9 A;  1IQE L;  4A7I A;  1HT5 A;  4Y7B B;  4NGA L;  2WPL E;  3IJE B;  1TPG A;  2AYL A;  4CUD A;  1UZP A;  1EZQ B;  3QCW A;  5JW1 A;  5L2Z L;  3LC5 B;  2GD4 A;  1C5M F;  3NTG A;  1AUT L;  2XC4 L;  3HO4 A;  4ISI L;  1KIG L;  6COX A;  4RRY A;  3LC3 B;  2J38 B;  4RUT A;  2W86 A;  5CKQ A;  1K37 A;  2WZP P;  2WFX B;  3KCG L;  2XC0 L;  2VH0 B;  2RNL A;  4AQT A;  4RRX A;  1P9J A;  2VJ3 A;  3QMO A;  1EQH A;  3HS6 A;  4YT7 L;  5JB8 E;  1IP0 A;  4Y79 B;  1CVW L;  1V3X B;  2PUQ L;  1B9W A;  3MQE A;  2Y5H L;  2KV4 A;  3SW2 A;  5JVZ A;  3QH0 A;  1PTH A;  3ASI A;  3Q7D A;  5EGM B;  1ATE A;  5KIR A;  1CX2 A;  1RFN B;  5L2Y L;  2NPR A;  1YUF A;  2WPM E;  2XBV L;  1EPH A;  1P0S L;  2J34 B;  2YGO A;  2MGP A;  4BDW A;  1YUK B;  1UZK A;  1GK5 A;  1HX2 A;  2P93 L;  3HO5 A;  1YO8 A;  5CKM A;  2K2S B;  2B7D L;  5L30 L;  1HAF A;  5K0H B;  5IKT A;  3KQC L;  4Y7A B;  5IKQ A;  4ZH8 B;  3KQE L;  2MGR A;  1IJQ A;  5IKR A;  2W2P E;  3LIW B;  5JBA E;  3SOV A;  5JBB E;  3ZYG A;  2BO2 A;  2I9A A;  1HRF A;  4C16 A;  1Z6E L;  3TH3 L;  2TGF A;  3Q3K B;  4BTU A;  3CEN L;  5IKV A;  3BT1 A;  1EPI A;  2D1J B;  3ZYJ B;  3P5B L;  4JYV L;  1G2M B;  3NT1 A;  4JYU L;  5F1A A;  1LMJ A;  2G00 L;  2BOK L;  3V65 B;  2P3F L;  2YGP A;  2WPJ E;  1I0U A;  4Y76 B;  3M37 L;  4PH9 A;  2UWP B;  1HJ7 A;  1G1Q A;  2YGQ A;  2Y82 B;  2EI8 B;  1HZ8 A;  1IQN L;  1MOX C;  1IVO C;  3N8X A;  1W8B L;  2WPH E;  2RHP A;  2P95 L;  4BTI A;  3K9X A;  1PGE A;  1CEJ A;  3LN0 A;  4E1G A;  3TBD A;  1EGF A;  4BTT A;  3OLU A;  4MMX B;  3FFG L;  3TGF A;  2W2M E;  4Y6D B;  4BXS A;  1LPG A;  1J9C L;  4MMY B;  1LPK A;  4RS0 A;  1QFK L;  1IQF L;  2J2U B;  1G1R A;  4Z0K B;  1YGC L;  5CIS A;  2P3T A;  1JBU L;  2P26 A;  3N8V A;  1IQG L;  1NT0 A;  1F7M A;  1LQD A;  4JZE L;  1IQH L;  1Q4G A;  1HAE A;  1TOZ A;  2FZZ L;  2VVC K;  1JV2 B;  1NQL B;  2P94 L;  1PFX L;  1XKB A;  4XL1 A;  3V64 C;  3HO3 A;  1PXX A;  2FLR L;  4CUE A;  5JB9 E;  2F9B L;  1WHE A;  2MHP A;  2P16 L;  3BT2 A;  4O02 B;  1CVU A;  2Y81 B;  1WU1 B;  3DEM A;  1KLO A;  1HCG B;  2WPK E;  2J94 B;  1SZB A;  1ADX A;  3OLT A;  1XFE A;  2BQ7 A;  3FCS B;  1CCV A;  1IGZ A;  3F6U L;  2UWO B;  2ADX A;  4M11 A;  1MQ5 L;  1FF7 A;  4Z0L A;  4YT6 L;  1DQB A;  1L3Y A;  1TLE A;  1KSN B;  4D0E A;  1IOX A;  3M36 L;  2FLG A;  2VVV L;  5E8D A;  5CKN A;  3PGH A;  5COX A;  1F7E A;  2P28 B;  2VWN L;  2WG3 C;  5I46 L;  1URK A;  4BXW A;  2DDU A;  2W2Q E;  3NTB A;  1CCF A;  2J4I B;  4G1M B;  3TK6 B;  2BOH A;  1F0S B;  2P3F N;  1WHF A;  1BF9 A;  3FBY A;  4OTY A;  1LPZ A;  1O5D L;  3H5C B;  2JKH L;  1FSB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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