2VVCK

Aminopyrrolidine factor xa inhibitor
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
53
structure length
53
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 12
structure length 53
sequence length 53
chains with identical sequence L
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2008-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2vvcK00
2PUQL 2P3FL 2P28B 4BXSA 4D0FA 1CCVA 2WYJB 3NT1A 4Y6DB 3SOVA 2BQ7A 2BOHA 3TK5B 1EGFA 3U73A 4ZHAB 4BTUA 2XBVL 1IP0A 2MGRA 2P3TA 5L30L 1YUGA 3LN0A 1COUA 4O1ZA 4ZH8B 4BDWA 2PHBB 6COXA 2BOXA 4Z6AL 2XBYL 1YUFA 3EGFA 1LQDA 1IVOC 1B9WA 2BO2A 2J34B 3K9XA 4M11A 2B7DL 4MMXB 1G1SA 3R05A 1P9JA 1F7EA 2P94L 2KL7A 1FSBA 4BDXA 2VVCK 3N8XA 2VJ3A 1WU1B 1MOXC 3FCSB 1MQ6L 1IQEL 4Y79B 1X7AL 1N1IA 4G1MB 1QFKL 2W2PE 2WG4B 2XBWL 4FM5A 3V65B 2KV4A 3BT2A 4CUEA 3ENSA 3CENL 4D0EA 3CS7L 1HZ8A 2P3UA 2FLGA 4ZXXL 3ELAL 1EPJA 3ZYGA 2BQWA 1UZPA 1CVWL 1NPEB 4D90A 3ZYJB 1JL9A 4OTYA 1XKBA 2VWLL 3SW2A 5JVZA 1UZQA 1LPZA 4NA9L 2Y80B 3KL6B 2BZ6L 3N8WA 2Y5FL 5JB9E 2XC5L 2M74A 4OTJA 2P3FN 5JB8E 3ZYIB 2GD4A 1NFWB 5IKTA 3GCWE 1ATDA 1IOEL 1L3YA 2Y7XB 1O5DL 1K37A 1NFXB 5JBCE 1F7MA 2WG3C 2AYLA 4Y71B 3RR3A 3TH3L 3TZIA 1EMOA 2W26B 1IQHL 5IKQA 3NTGA 2P95L 2BOUA 1APOA 1WHEA 3LAQA 1HRFA 2FLBL 2W86A 1IOXA 2H9EL 3HO3A 1IGZA 2XC0L 2YGPA 3MDLA 1IQIL 3Q3KB 1FFMA 1U67A 2WPLE 1IQNL 4ISHL 3C9AC 4YZUB 1Q4GA 2BMGA 3N8ZA 3OLUA 1UZKA 4COXA 1EMNA 3DEMA 2WPME 5CKNA 2W2ME 4JZFL 5E8DA 3CA7A 3LC3B 2J95B 4JZDL 4XLWA 1CVUA 2EI7B 4CUDA 4JYVL 1IQGL 2K2SB 2P93L 5F1AA 3LTFB 2I9BA 4M10A 3KRKA 4XBMA 4LMFA 1L5GB 1CCFA 3FFGL 3POYA 2P16L 2VVUL 1OB1C 3LN1A 1N7DA 2FLRL 4X8UL 3U7UG 2Y82B 2RA0L 1KLOA 3V64C 1A3PA 1ADXA 2Q1JB 1HCGB 1HT8A 1PRHA 2XC4L 1J9CL 1U8CB 5JVYA 1KLJL 4JZEL 3BPSE 4RUTA 1WHFA 1XFEA 1EQGA 2BQ6A 1KIGL 3HS7A 2VH6B 1IQJL 2RHPA 1NFYB 1FAKL 4Z0LA 3SOBB 2UWPB 2MGPA 5I46L 2WPHE 2XBXL 1W7XL 3N8WB 3HS6A 3TBDA 1G1QA 1G2MB 1IQFL 2J4IB 2WPIE 3Q7DA 1ATAA 3M37L 1DQBA 2W3IB 4A7IA 1URKA 3M36L 4CUFA 1ZAQA 5L2ZL 2OYEP 4NG9L 1F0SB 4TGFA 3GCXE 1DIYA 1PTHA 1MQ5L 1FF7A 2Y81B 5KN5C 4E1GA 2FD6A 2YGOA 1PXXA 1HREA 4JYUL 2PR3B 3KCGL 3MQEA 1IJQA 1IGXA 4AQTA 3QMOA 2W2QE 2J38B 3KK6A 2WPJE 3ASIA 3N8VA 2TGFA 2VWMK 3NJPC 1NZIA 4RRWA 3FBYA 4CSYA 3SOQA 3GISX 4MMYB 4LORA 1EPHA 1GK5A 1TOZA 1G1TA 4Y7BB 2NPRA 5K0HB 1EPGA 5JW1A 1KLIL 2W2OE 4NGAL 3TGFA 1EBVA 1PFXL 2RNLA 2EI6B 3F6UL 1DDXA 4O02B 5CKQA 4BTIA 2VH0B 1IQKL 3N8YA 5L2YL 1CX2A 2WPKE 1KSNB 4X8SL 3F1SB 1HT5A 3LIWB 5CKMA 1ATBA 4MMZB 1FJSL 4X8VL 1NT0A 1C5MF 4RRYA 1TLEA 3KQCL 1HAFA 4Y76B 1YUKB 1UZJA 2DDUA 1P0SL 2WYGB 2WFTA 1DVAL 2EI8B 2K2TA 2VVVL 4PH9A 2G00L 3HS5A 1NQLB 3KQDL 2FZZL 1LPGA 2P26A 4XL1A 4ZXYL 1LPKA 4ISIL 3H5CB 3TK6B 1XKAL 2JKHL 2W3KB 1TPGA 1G1RA 5COXA 3LTGD 3KQEL 5F19A 1EQHA 4YT7L 3HO5A 4RS0A 1CQEA 1AUTL 2Y5HL 4BTTA 2CJIB 1CEJA 2BOKL 1F0RB 4X8TL 4C16A 1FAXL 1NFUB 2I9AA 3QH0A 3QCWA 4YT6L 5JBAE 2Y5GL 2WFXB 3HPTA 1LMJA 1BF9A 2Y7ZB 1M1XB 1IQLL 1HAEA 2ADXA 1EZQB 2J2UB 3IJEB 2UWLB 3OLTA 3P5BL 1Z6CA 1JBUL 2W2NE 4RRXA 1ATEA 1G2LB 1Z6EL 2VWOL 1JV2B 4BXWA 1I0UA 1EPIA 3LC5B 3N8YB 4Z0KB 3IITB 5IKRA 2F9BL 1YO8A 3BT1A 3CFWA 4ZAEB 3HO4A 1W8BL 5EGMB 1RFNB 1XDTR 2J94B 5KIRA 5IKVA 5JBBE 2VWNL 1IQML 3NTBA 2D1JB 5CISA 1FE2A 3KQBL 1APQA 1PGEA 1K36A 4Y7AB 4RRZA 2Y38A 1DX5I 2MHPA 3PGHA 2UWOB 2KB9A 1HX2A 1V3XB 1SZBA 2OYUP 1YGCL 1EAIC 1HJ7A 5FDQA
chains in the Genus database with same CATH superfamily
2PUQL 2P3FL 2P28B 4BXSA 4D0FA 1CCVA 2WYJB 3NT1A 2JJLA 4Y6DB 3SOVA 2BQ7A 2BOHA 3TK5B 1EGFA 3U73A 4ZHAB 4BTUA 2XBVL 1IP0A 2MGRA 2P3TA 5L30L 1YUGA 3LN0A 1COUA 4O1ZA 4ZH8B 4BDWA 2PHBB 6COXA 2BOXA 1LMMA 4Z6AL 2XBYL 1YUFA 3EGFA 1LQDA 1IVOC 1B9WA 2BO2A 2J34B 3K9XA 4M11A 2B7DL 4MMXB 1G1SA 3R05A 1P9JA 1F7EA 2P94L 2KL7A 1FSBA 4BDXA 2VVCK 3N8XA 2VJ3A 1WU1B 1MOXC 3FCSB 1MQ6L 1IQEL 4Y79B 1X7AL 1N1IA 4G1MB 1QFKL 2W2PE 2WG4B 2XBWL 4FM5A 3V65B 2KV4A 3BT2A 4CUEA 3ENSA 3CENL 4D0EA 3CS7L 1HZ8A 2P3UA 2FLGA 4ZXXL 3ELAL 1EPJA 3ZYGA 2BQWA 1UZPA 1CVWL 1NPEB 4D90A 3ZYJB 1JL9A 2BSFA 4OTYA 1XKBA 2VWLL 3SW2A 5JVZA 1UZQA 1LPZA 4NA9L 2Y80B 3KL6B 2BZ6L 3N8WA 2Y5FL 5JB9E 2XC5L 2M74A 4OTJA 2P3FN 5JB8E 1V1HA 3ZYIB 2GD4A 1NFWB 5IKTA 3GCWE 1ATDA 1IOEL 1L3YA 2Y7XB 1O5DL 1K37A 1NFXB 5JBCE 1F7MA 2WG3C 4A94C 2AYLA 4Y71B 3RR3A 3TH3L 3TZIA 1EMOA 2W26B 1IQHL 5IKQA 3NTGA 2P95L 2BOUA 1APOA 1WHEA 3LAQA 1HRFA 2FLBL 2W86A 1IOXA 2H9EL 3HO3A 1IGZA 2XC0L 1QIUA 2YGPA 3MDLA 1IQIL 3Q3KB 1FFMA 1U67A 2WPLE 1IQNL 4ISHL 3C9AC 4YZUB 1Q4GA 2BMGA 3N8ZA 3OLUA 1UZKA 4COXA 1EMNA 3DEMA 2WPME 5CKNA 2W2ME 4JZFL 5E8DA 3CA7A 3LC3B 2HORA 2J95B 4JZDL 4XLWA 1CVUA 2EI7B 4CUDA 4JYVL 1IQGL 2K2SB 2P93L 5F1AA 3LTFB 2I9BA 4M10A 3KRKA 4XBMA 4LMFA 1L5GB 1CCFA 3FFGL 3POYA 2P16L 2VVUL 1OB1C 3LN1A 1N7DA 2FLRL 4X8UL 3U7UG 2Y82B 2RA0L 1KLOA 3V64C 1A3PA 1ADXA 2Q1JB 1HCGB 1HT8A 1PRHA 2XC4L 1J9CL 1U8CB 5JVYA 1KLJL 4JZEL 3BPSE 1V1IA 4RUTA 1WHFA 1XFEA 1EQGA 2BQ6A 1KIGL 3HS7A 2VH6B 1IQJL 2KNIA 2RHPA 1NFYB 1FAKL 4Z0LA 3SOBB 2UWPB 2MGPA 5I46L 2WPHE 2XBXL 1W7XL 3N8WB 3HS6A 3TBDA 1G1QA 1G2MB 4GU4A 1IQFL 2J4IB 2WPIE 3Q7DA 1ATAA 3M37L 1DQBA 2W3IB 4A7IA 1URKA 3M36L 4CUFA 1ZAQA 5L2ZL 2OYEP 4NG9L 1F0SB 2YGQA 3GCXE 4TGFA 1DIYA 1PTHA 1MQ5L 1FF7A 2Y81B 5KN5C 4E1GA 2FD6A 2YGOA 1PXXA 1HREA 4JYUL 2PR3B 3KCGL 3MQEA 1IJQA 1IGXA 4AQTA 3QMOA 2W2QE 2J38B 3KK6A 2WPJE 3ASIA 3N8VA 2TGFA 2VWMK 3NJPC 1NZIA 4RRWA 3FBYA 2BT7A 4CSYA 3SOQA 3GISX 4MMYB 4LORA 1EPHA 1GK5A 1TOZA 1G1TA 4Y7BB 2NPRA 5K0HB 1EPGA 5JW1A 1KLIL 2W2OE 4NGAL 3TGFA 1EBVA 1PFXL 2RNLA 2EI6B 3F6UL 1DDXA 4O02B 5CKQA 4BTIA 2VH0B 1IQKL 3N8YA 5L2YL 1CX2A 2WPKE 1KSNB 4X8SL 3F1SB 1HT5A 3LIWB 5CKMA 1ATBA 4MMZB 1FJSL 4X8VL 2BT8A 1NT0A 1C5MF 4RRYA 1TLEA 3KQCL 1HAFA 4Y76B 1YUKB 1UZJA 2DDUA 1P0SL 2WYGB 2WFTA 1DVAL 2EI8B 2K2TA 2VVVL 4PH9A 3HS5A 1LK9A 2G00L 1NQLB 3KQDL 2FZZL 2VRSA 1LPGA 2P26A 4XL1A 4ZXYL 1LPKA 4ISIL 3H5CB 3TK6B 1XKAL 2JKHL 2W3KB 1TPGA 1G1RA 5COXA 3LTGD 3KQEL 5F19A 1EQHA 4YT7L 3HO5A 4RS0A 1CQEA 1AUTL 2Y5HL 4BTTA 2CJIB 1CEJA 2BOKL 1F0RB 4X8TL 4C16A 1FAXL 2WZPP 1NFUB 2I9AA 3QH0A 3QCWA 4YT6L 5JBAE 2Y5GL 2WFXB 3HPTA 1LMJA 2HOXA 1BF9A 2Y7ZB 1M1XB 1IQLL 1HAEA 2ADXA 1EZQB 2J2UB 3IJEB 2UWLB 3OLTA 3P5BL 1Z6CA 2H9EC 1JBUL 2W2NE 1KKEA 4RRXA 1ATEA 1G2LB 1Z6EL 2VWOL 4GU3A 1JV2B 4BXWA 1I0UA 1EPIA 3LC5B 3N8YB 4Z0KB 3IITB 5IKRA 2F9BL 1YO8A 3BT1A 3CFWA 3S6XA 4ZAEB 3HO4A 1W8BL 5EGMB 1RFNB 1XDTR 2J94B 5KIRA 5IKVA 5JBBE 2VWNL 1IQML 3NTBA 2D1JB 5CISA 1FE2A 3KQBL 1APQA 1PGEA 1K36A 4Y7AB 4RRZA 2Y38A 1DX5I 2MHPA 3PGHA 2UWOB 2KB9A 1HX2A 1V3XB 1SZBA 2OYUP 1YGCL 1EAIC 1HJ7A 5FDQA
chains in the Genus database with same CATH topology
2PUQL 2P3FL 2P28B 4BXSA 4D0FA 1CCVA 2WYJB 3NT1A 4Y6DB 3SOVA 2BQ7A 2BOHA 3TK5B 1EGFA 3U73A 4ZHAB 4BTUA 2XBVL 1IP0A 2MGRA 2P3TA 5L30L 1YUGA 3LN0A 1COUA 4O1ZA 4ZH8B 4BDWA 2PHBB 6COXA 2BOXA 1LMMA 4Z6AL 2XBYL 1YUFA 3EGFA 1LQDA 1IVOC 1B9WA 2BO2A 2J34B 3K9XA 4M11A 2B7DL 4MMXB 1G1SA 3R05A 1P9JA 1F7EA 2P94L 2KL7A 1FSBA 4BDXA 2VVCK 3N8XA 2VJ3A 1WU1B 1MOXC 3FCSB 1MQ6L 1IQEL 4Y79B 1X7AL 1N1IA 4G1MB 1QFKL 2W2PE 2WG4B 2XBWL 4FM5A 3V65B 2KV4A 3BT2A 4CUEA 3ENSA 3CENL 4D0EA 3CS7L 1HZ8A 2P3UA 2FLGA 4ZXXL 3ELAL 1EPJA 3ZYGA 2BQWA 1UZPA 1CVWL 1NPEB 4D90A 3ZYJB 1JL9A 4OTYA 1XKBA 2VWLL 3SW2A 5JVZA 1UZQA 1LPZA 4NA9L 2Y80B 3KL6B 2BZ6L 3N8WA 2Y5FL 5JB9E 2XC5L 2M74A 4OTJA 2P3FN 5JB8E 3ZYIB 2GD4A 1NFWB 5IKTA 3GCWE 1ATDA 1IOEL 1L3YA 2Y7XB 1O5DL 1K37A 1NFXB 5JBCE 1F7MA 2WG3C 4A94C 2AYLA 4Y71B 3RR3A 3TH3L 3TZIA 1EMOA 2W26B 1IQHL 5IKQA 3NTGA 2P95L 2BOUA 1APOA 1WHEA 3LAQA 1HRFA 2FLBL 2W86A 1IOXA 2H9EL 3HO3A 1IGZA 2XC0L 2YGPA 3MDLA 1IQIL 3Q3KB 1FFMA 1U67A 2WPLE 1IQNL 4ISHL 3C9AC 4YZUB 1Q4GA 2BMGA 3N8ZA 3OLUA 1UZKA 4COXA 1EMNA 3DEMA 2WPME 5CKNA 2W2ME 4JZFL 5E8DA 3CA7A 3LC3B 2J95B 4JZDL 4XLWA 1CVUA 2EI7B 4CUDA 4JYVL 1IQGL 2K2SB 2P93L 5F1AA 3LTFB 2I9BA 4M10A 3KRKA 4XBMA 4LMFA 1L5GB 1CCFA 3FFGL 3POYA 2P16L 2VVUL 1OB1C 3LN1A 1N7DA 2FLRL 4X8UL 3U7UG 2Y82B 2RA0L 1KLOA 3V64C 1A3PA 1ADXA 2Q1JB 1HCGB 1HT8A 1PRHA 2XC4L 1J9CL 1U8CB 5JVYA 1KLJL 4JZEL 3BPSE 4RUTA 1WHFA 1XFEA 1EQGA 2BQ6A 1KIGL 3HS7A 2VH6B 1IQJL 2KNIA 2RHPA 1NFYB 1FAKL 4Z0LA 3SOBB 2UWPB 2MGPA 5I46L 2WPHE 2XBXL 1W7XL 3N8WB 3HS6A 3TBDA 1G1QA 1G2MB 1IQFL 2J4IB 2WPIE 3Q7DA 1ATAA 3M37L 1DQBA 2W3IB 4A7IA 1URKA 3M36L 4CUFA 1ZAQA 5L2ZL 2OYEP 4NG9L 1F0SB 2YGQA 3GCXE 4TGFA 1DIYA 1PTHA 1MQ5L 1FF7A 2Y81B 5KN5C 4E1GA 2FD6A 2YGOA 1PXXA 1HREA 4JYUL 2PR3B 3KCGL 3MQEA 1IJQA 1IGXA 4AQTA 3QMOA 2W2QE 2J38B 3KK6A 2WPJE 3ASIA 3N8VA 2TGFA 2VWMK 3NJPC 1NZIA 4RRWA 3FBYA 4CSYA 3SOQA 3GISX 4MMYB 4LORA 1EPHA 1GK5A 1TOZA 1G1TA 4Y7BB 2NPRA 5K0HB 1EPGA 5JW1A 1KLIL 2W2OE 4NGAL 3TGFA 1EBVA 1PFXL 2RNLA 2EI6B 3F6UL 1DDXA 4O02B 5CKQA 4BTIA 2VH0B 1IQKL 3N8YA 5L2YL 1CX2A 2WPKE 1KSNB 4X8SL 3F1SB 1HT5A 3LIWB 5CKMA 1ATBA 4MMZB 1FJSL 4X8VL 1NT0A 1C5MF 4RRYA 1TLEA 3KQCL 1HAFA 4Y76B 1YUKB 1UZJA 2DDUA 1P0SL 2WYGB 2WFTA 1DVAL 2EI8B 2K2TA 2VVVL 4PH9A 2G00L 3HS5A 1NQLB 3KQDL 2FZZL 1LPGA 2P26A 4XL1A 4ZXYL 1LPKA 4ISIL 3H5CB 3TK6B 1XKAL 2JKHL 2W3KB 1TPGA 1G1RA 5COXA 3LTGD 3KQEL 5F19A 1EQHA 4YT7L 3HO5A 4RS0A 1CQEA 1AUTL 2Y5HL 4BTTA 2CJIB 1CEJA 2BOKL 1F0RB 4X8TL 4C16A 1FAXL 2WZPP 1NFUB 2I9AA 3QH0A 3QCWA 4YT6L 5JBAE 2Y5GL 2WFXB 3HPTA 1LMJA 1BF9A 2Y7ZB 1M1XB 1IQLL 1HAEA 2ADXA 1EZQB 2J2UB 3IJEB 2UWLB 3OLTA 3P5BL 1Z6CA 2H9EC 1JBUL 2W2NE 4RRXA 1ATEA 1G2LB 1Z6EL 2VWOL 1JV2B 4BXWA 1I0UA 1EPIA 3LC5B 3N8YB 4Z0KB 3IITB 5IKRA 2F9BL 1YO8A 3BT1A 3CFWA 3S6XA 4ZAEB 3HO4A 1W8BL 5EGMB 1RFNB 1XDTR 2J94B 5KIRA 5IKVA 5JBBE 2VWNL 1IQML 3NTBA 2D1JB 5CISA 1FE2A 3KQBL 1APQA 1PGEA 1K36A 4Y7AB 4RRZA 2Y38A 1DX5I 2MHPA 3PGHA 2UWOB 2KB9A 1HX2A 1V3XB 1SZBA 2OYUP 1YGCL 1EAIC 1HJ7A 5FDQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PUQ L;  2P3F L;  2P28 B;  4BXS A;  4D0F A;  1CCV A;  2WYJ B;  3NT1 A;  4Y6D B;  3SOV A;  2BQ7 A;  2BOH A;  3TK5 B;  1EGF A;  3U73 A;  4ZHA B;  4BTU A;  2XBV L;  1IP0 A;  2MGR A;  2P3T A;  5L30 L;  1YUG A;  3LN0 A;  1COU A;  4O1Z A;  4ZH8 B;  4BDW A;  2PHB B;  6COX A;  2BOX A;  4Z6A L;  2XBY L;  1YUF A;  3EGF A;  1LQD A;  1IVO C;  1B9W A;  2BO2 A;  2J34 B;  3K9X A;  4M11 A;  2B7D L;  4MMX B;  1G1S A;  3R05 A;  1P9J A;  1F7E A;  2P94 L;  2KL7 A;  1FSB A;  4BDX A;  2VVC K;  3N8X A;  2VJ3 A;  1WU1 B;  1MOX C;  3FCS B;  1MQ6 L;  1IQE L;  4Y79 B;  1X7A L;  1N1I A;  4G1M B;  1QFK L;  2W2P E;  2WG4 B;  2XBW L;  4FM5 A;  3V65 B;  2KV4 A;  3BT2 A;  4CUE A;  3ENS A;  3CEN L;  4D0E A;  3CS7 L;  1HZ8 A;  2P3U A;  2FLG A;  4ZXX L;  3ELA L;  1EPJ A;  3ZYG A;  2BQW A;  1UZP A;  1CVW L;  1NPE B;  4D90 A;  3ZYJ B;  1JL9 A;  4OTY A;  1XKB A;  2VWL L;  3SW2 A;  5JVZ A;  1UZQ A;  1LPZ A;  4NA9 L;  2Y80 B;  3KL6 B;  2BZ6 L;  3N8W A;  2Y5F L;  5JB9 E;  2XC5 L;  2M74 A;  4OTJ A;  2P3F N;  5JB8 E;  3ZYI B;  2GD4 A;  1NFW B;  5IKT A;  3GCW E;  1ATD A;  1IOE L;  1L3Y A;  2Y7X B;  1O5D L;  1K37 A;  1NFX B;  5JBC E;  1F7M A;  2WG3 C;  2AYL A;  4Y71 B;  3RR3 A;  3TH3 L;  3TZI A;  1EMO A;  2W26 B;  1IQH L;  5IKQ A;  3NTG A;  2P95 L;  2BOU A;  1APO A;  1WHE A;  3LAQ A;  1HRF A;  2FLB L;  2W86 A;  1IOX A;  2H9E L;  3HO3 A;  1IGZ A;  2XC0 L;  2YGP A;  3MDL A;  1IQI L;  3Q3K B;  1FFM A;  1U67 A;  2WPL E;  1IQN L;  4ISH L;  3C9A C;  4YZU B;  1Q4G A;  2BMG A;  3N8Z A;  3OLU A;  1UZK A;  4COX A;  1EMN A;  3DEM A;  2WPM E;  5CKN A;  2W2M E;  4JZF L;  5E8D A;  3CA7 A;  3LC3 B;  2J95 B;  4JZD L;  4XLW A;  1CVU A;  2EI7 B;  4CUD A;  4JYV L;  1IQG L;  2K2S B;  2P93 L;  5F1A A;  3LTF B;  2I9B A;  4M10 A;  3KRK A;  4XBM A;  4LMF A;  1L5G B;  1CCF A;  3FFG L;  3POY A;  2P16 L;  2VVU L;  1OB1 C;  3LN1 A;  1N7D A;  2FLR L;  4X8U L;  3U7U G;  2Y82 B;  2RA0 L;  1KLO A;  3V64 C;  1A3P A;  1ADX A;  2Q1J B;  1HCG B;  1HT8 A;  1PRH A;  2XC4 L;  1J9C L;  1U8C B;  5JVY A;  1KLJ L;  4JZE L;  3BPS E;  4RUT A;  1WHF A;  1XFE A;  1EQG A;  2BQ6 A;  1KIG L;  3HS7 A;  2VH6 B;  1IQJ L;  2RHP A;  1NFY B;  1FAK L;  4Z0L A;  3SOB B;  2UWP B;  2MGP A;  5I46 L;  2WPH E;  2XBX L;  1W7X L;  3N8W B;  3HS6 A;  3TBD A;  1G1Q A;  1G2M B;  1IQF L;  2J4I B;  2WPI E;  3Q7D A;  1ATA A;  3M37 L;  1DQB A;  2W3I B;  4A7I A;  1URK A;  3M36 L;  4CUF A;  1ZAQ A;  5L2Z L;  2OYE P;  4NG9 L;  1F0S B;  4TGF A;  3GCX E;  1DIY A;  1PTH A;  1MQ5 L;  1FF7 A;  2Y81 B;  5KN5 C;  4E1G A;  2FD6 A;  2YGO A;  1PXX A;  1HRE A;  4JYU L;  2PR3 B;  3KCG L;  3MQE A;  1IJQ A;  1IGX A;  4AQT A;  3QMO A;  2W2Q E;  2J38 B;  3KK6 A;  2WPJ E;  3ASI A;  3N8V A;  2TGF A;  2VWM K;  3NJP C;  1NZI A;  4RRW A;  3FBY A;  4CSY A;  3SOQ A;  3GIS X;  4MMY B;  4LOR A;  1EPH A;  1GK5 A;  1TOZ A;  1G1T A;  4Y7B B;  2NPR A;  5K0H B;  1EPG A;  5JW1 A;  1KLI L;  2W2O E;  4NGA L;  3TGF A;  1EBV A;  1PFX L;  2RNL A;  2EI6 B;  3F6U L;  1DDX A;  4O02 B;  5CKQ A;  4BTI A;  2VH0 B;  1IQK L;  3N8Y A;  5L2Y L;  1CX2 A;  2WPK E;  1KSN B;  4X8S L;  3F1S B;  1HT5 A;  3LIW B;  5CKM A;  1ATB A;  4MMZ B;  1FJS L;  4X8V L;  1NT0 A;  1C5M F;  4RRY A;  1TLE A;  3KQC L;  1HAF A;  4Y76 B;  1YUK B;  1UZJ A;  2DDU A;  1P0S L;  2WYG B;  2WFT A;  1DVA L;  2EI8 B;  2K2T A;  2VVV L;  4PH9 A;  2G00 L;  3HS5 A;  1NQL B;  3KQD L;  2FZZ L;  1LPG A;  2P26 A;  4XL1 A;  4ZXY L;  1LPK A;  4ISI L;  3H5C B;  3TK6 B;  1XKA L;  2JKH L;  2W3K B;  1TPG A;  1G1R A;  5COX A;  3LTG D;  3KQE L;  5F19 A;  1EQH A;  4YT7 L;  3HO5 A;  4RS0 A;  1CQE A;  1AUT L;  2Y5H L;  4BTT A;  2CJI B;  1CEJ A;  2BOK L;  1F0R B;  4X8T L;  4C16 A;  1FAX L;  1NFU B;  2I9A A;  3QH0 A;  3QCW A;  4YT6 L;  5JBA E;  2Y5G L;  2WFX B;  3HPT A;  1LMJ A;  1BF9 A;  2Y7Z B;  1M1X B;  1IQL L;  1HAE A;  2ADX A;  1EZQ B;  2J2U B;  3IJE B;  2UWL B;  3OLT A;  3P5B L;  1Z6C A;  1JBU L;  2W2N E;  4RRX A;  1ATE A;  1G2L B;  1Z6E L;  2VWO L;  1JV2 B;  4BXW A;  1I0U A;  1EPI A;  3LC5 B;  3N8Y B;  4Z0K B;  3IIT B;  5IKR A;  2F9B L;  1YO8 A;  3BT1 A;  3CFW A;  4ZAE B;  3HO4 A;  1W8B L;  5EGM B;  1RFN B;  1XDT R;  2J94 B;  5KIR A;  5IKV A;  5JBB E;  2VWN L;  1IQM L;  3NTB A;  2D1J B;  5CIS A;  1FE2 A;  3KQB L;  1APQ A;  1PGE A;  1K36 A;  4Y7A B;  4RRZ A;  2Y38 A;  1DX5 I;  2MHP A;  3PGH A;  2UWO B;  2KB9 A;  1HX2 A;  1V3X B;  1SZB A;  2OYU P;  1YGC L;  1EAI C;  1HJ7 A;  5FDQ A; 
#chains in the Genus database with same CATH topology
 2PUQ L;  2P3F L;  2P28 B;  4BXS A;  4D0F A;  1CCV A;  2WYJ B;  3NT1 A;  2JJL A;  4Y6D B;  3SOV A;  2BQ7 A;  2BOH A;  3TK5 B;  1EGF A;  3U73 A;  4ZHA B;  4BTU A;  2XBV L;  1IP0 A;  2MGR A;  2P3T A;  5L30 L;  1YUG A;  3LN0 A;  1COU A;  4O1Z A;  4ZH8 B;  4BDW A;  2PHB B;  6COX A;  2BOX A;  1LMM A;  4Z6A L;  2XBY L;  1YUF A;  3EGF A;  1LQD A;  1IVO C;  1B9W A;  2BO2 A;  2J34 B;  3K9X A;  4M11 A;  2B7D L;  4MMX B;  1G1S A;  3R05 A;  1P9J A;  1F7E A;  2P94 L;  2KL7 A;  1FSB A;  4BDX A;  2VVC K;  3N8X A;  2VJ3 A;  1WU1 B;  1MOX C;  3FCS B;  1MQ6 L;  1IQE L;  4Y79 B;  1X7A L;  1N1I A;  4G1M B;  1QFK L;  2W2P E;  2WG4 B;  2XBW L;  4FM5 A;  3V65 B;  2KV4 A;  3BT2 A;  4CUE A;  3ENS A;  3CEN L;  4D0E A;  3CS7 L;  1HZ8 A;  2P3U A;  2FLG A;  4ZXX L;  3ELA L;  1EPJ A;  3ZYG A;  2BQW A;  1UZP A;  1CVW L;  1NPE B;  4D90 A;  3ZYJ B;  1JL9 A;  2BSF A;  4OTY A;  1XKB A;  2VWL L;  3SW2 A;  5JVZ A;  1UZQ A;  1LPZ A;  4NA9 L;  2Y80 B;  3KL6 B;  2BZ6 L;  3N8W A;  2Y5F L;  5JB9 E;  2XC5 L;  2M74 A;  4OTJ A;  2P3F N;  5JB8 E;  1V1H A;  3ZYI B;  2GD4 A;  1NFW B;  5IKT A;  3GCW E;  1ATD A;  1IOE L;  1L3Y A;  2Y7X B;  1O5D L;  1K37 A;  1NFX B;  5JBC E;  1F7M A;  2WG3 C;  4A94 C;  2AYL A;  4Y71 B;  3RR3 A;  3TH3 L;  3TZI A;  1EMO A;  2W26 B;  1IQH L;  5IKQ A;  3NTG A;  2P95 L;  2BOU A;  1APO A;  1WHE A;  3LAQ A;  1HRF A;  2FLB L;  2W86 A;  1IOX A;  2H9E L;  3HO3 A;  1IGZ A;  2XC0 L;  1QIU A;  2YGP A;  3MDL A;  1IQI L;  3Q3K B;  1FFM A;  1U67 A;  2WPL E;  1IQN L;  4ISH L;  3C9A C;  4YZU B;  1Q4G A;  2BMG A;  3N8Z A;  3OLU A;  1UZK A;  4COX A;  1EMN A;  3DEM A;  2WPM E;  5CKN A;  2W2M E;  4JZF L;  5E8D A;  3CA7 A;  3LC3 B;  2HOR A;  2J95 B;  4JZD L;  4XLW A;  1CVU A;  2EI7 B;  4CUD A;  4JYV L;  1IQG L;  2K2S B;  2P93 L;  5F1A A;  3LTF B;  2I9B A;  4M10 A;  3KRK A;  4XBM A;  4LMF A;  1L5G B;  1CCF A;  3FFG L;  3POY A;  2P16 L;  2VVU L;  1OB1 C;  3LN1 A;  1N7D A;  2FLR L;  4X8U L;  3U7U G;  2Y82 B;  2RA0 L;  1KLO A;  3V64 C;  1A3P A;  1ADX A;  2Q1J B;  1HCG B;  1HT8 A;  1PRH A;  2XC4 L;  1J9C L;  1U8C B;  5JVY A;  1KLJ L;  4JZE L;  3BPS E;  1V1I A;  4RUT A;  1WHF A;  1XFE A;  1EQG A;  2BQ6 A;  1KIG L;  3HS7 A;  2VH6 B;  1IQJ L;  2KNI A;  2RHP A;  1NFY B;  1FAK L;  4Z0L A;  3SOB B;  2UWP B;  2MGP A;  5I46 L;  2WPH E;  2XBX L;  1W7X L;  3N8W B;  3HS6 A;  3TBD A;  1G1Q A;  1G2M B;  4GU4 A;  1IQF L;  2J4I B;  2WPI E;  3Q7D A;  1ATA A;  3M37 L;  1DQB A;  2W3I B;  4A7I A;  1URK A;  3M36 L;  4CUF A;  1ZAQ A;  5L2Z L;  2OYE P;  4NG9 L;  1F0S B;  2YGQ A;  3GCX E;  4TGF A;  1DIY A;  1PTH A;  1MQ5 L;  1FF7 A;  2Y81 B;  5KN5 C;  4E1G A;  2FD6 A;  2YGO A;  1PXX A;  1HRE A;  4JYU L;  2PR3 B;  3KCG L;  3MQE A;  1IJQ A;  1IGX A;  4AQT A;  3QMO A;  2W2Q E;  2J38 B;  3KK6 A;  2WPJ E;  3ASI A;  3N8V A;  2TGF A;  2VWM K;  3NJP C;  1NZI A;  4RRW A;  3FBY A;  2BT7 A;  4CSY A;  3SOQ A;  3GIS X;  4MMY B;  4LOR A;  1EPH A;  1GK5 A;  1TOZ A;  1G1T A;  4Y7B B;  2NPR A;  5K0H B;  1EPG A;  5JW1 A;  1KLI L;  2W2O E;  4NGA L;  3TGF A;  1EBV A;  1PFX L;  2RNL A;  2EI6 B;  3F6U L;  1DDX A;  4O02 B;  5CKQ A;  4BTI A;  2VH0 B;  1IQK L;  3N8Y A;  5L2Y L;  1CX2 A;  2WPK E;  1KSN B;  4X8S L;  3F1S B;  1HT5 A;  3LIW B;  5CKM A;  1ATB A;  4MMZ B;  1FJS L;  4X8V L;  2BT8 A;  1NT0 A;  1C5M F;  4RRY A;  1TLE A;  3KQC L;  1HAF A;  4Y76 B;  1YUK B;  1UZJ A;  2DDU A;  1P0S L;  2WYG B;  2WFT A;  1DVA L;  2EI8 B;  2K2T A;  2VVV L;  4PH9 A;  3HS5 A;  1LK9 A;  2G00 L;  1NQL B;  3KQD L;  2FZZ L;  2VRS A;  1LPG A;  2P26 A;  4XL1 A;  4ZXY L;  1LPK A;  4ISI L;  3H5C B;  3TK6 B;  1XKA L;  2JKH L;  2W3K B;  1TPG A;  1G1R A;  5COX A;  3LTG D;  3KQE L;  5F19 A;  1EQH A;  4YT7 L;  3HO5 A;  4RS0 A;  1CQE A;  1AUT L;  2Y5H L;  4BTT A;  2CJI B;  1CEJ A;  2BOK L;  1F0R B;  4X8T L;  4C16 A;  1FAX L;  2WZP P;  1NFU B;  2I9A A;  3QH0 A;  3QCW A;  4YT6 L;  5JBA E;  2Y5G L;  2WFX B;  3HPT A;  1LMJ A;  2HOX A;  1BF9 A;  2Y7Z B;  1M1X B;  1IQL L;  1HAE A;  2ADX A;  1EZQ B;  2J2U B;  3IJE B;  2UWL B;  3OLT A;  3P5B L;  1Z6C A;  2H9E C;  1JBU L;  2W2N E;  1KKE A;  4RRX A;  1ATE A;  1G2L B;  1Z6E L;  2VWO L;  4GU3 A;  1JV2 B;  4BXW A;  1I0U A;  1EPI A;  3LC5 B;  3N8Y B;  4Z0K B;  3IIT B;  5IKR A;  2F9B L;  1YO8 A;  3BT1 A;  3CFW A;  3S6X A;  4ZAE B;  3HO4 A;  1W8B L;  5EGM B;  1RFN B;  1XDT R;  2J94 B;  5KIR A;  5IKV A;  5JBB E;  2VWN L;  1IQM L;  3NTB A;  2D1J B;  5CIS A;  1FE2 A;  3KQB L;  1APQ A;  1PGE A;  1K36 A;  4Y7A B;  4RRZ A;  2Y38 A;  1DX5 I;  2MHP A;  3PGH A;  2UWO B;  2KB9 A;  1HX2 A;  1V3X B;  1SZB A;  2OYU P;  1YGC L;  1EAI C;  1HJ7 A;  5FDQ A; 
#chains in the Genus database with same CATH homology
 2PUQ L;  2P3F L;  2P28 B;  4BXS A;  4D0F A;  1CCV A;  2WYJ B;  3NT1 A;  4Y6D B;  3SOV A;  2BQ7 A;  2BOH A;  3TK5 B;  1EGF A;  3U73 A;  4ZHA B;  4BTU A;  2XBV L;  1IP0 A;  2MGR A;  2P3T A;  5L30 L;  1YUG A;  3LN0 A;  1COU A;  4O1Z A;  4ZH8 B;  4BDW A;  2PHB B;  6COX A;  2BOX A;  1LMM A;  4Z6A L;  2XBY L;  1YUF A;  3EGF A;  1LQD A;  1IVO C;  1B9W A;  2BO2 A;  2J34 B;  3K9X A;  4M11 A;  2B7D L;  4MMX B;  1G1S A;  3R05 A;  1P9J A;  1F7E A;  2P94 L;  2KL7 A;  1FSB A;  4BDX A;  2VVC K;  3N8X A;  2VJ3 A;  1WU1 B;  1MOX C;  3FCS B;  1MQ6 L;  1IQE L;  4Y79 B;  1X7A L;  1N1I A;  4G1M B;  1QFK L;  2W2P E;  2WG4 B;  2XBW L;  4FM5 A;  3V65 B;  2KV4 A;  3BT2 A;  4CUE A;  3ENS A;  3CEN L;  4D0E A;  3CS7 L;  1HZ8 A;  2P3U A;  2FLG A;  4ZXX L;  3ELA L;  1EPJ A;  3ZYG A;  2BQW A;  1UZP A;  1CVW L;  1NPE B;  4D90 A;  3ZYJ B;  1JL9 A;  4OTY A;  1XKB A;  2VWL L;  3SW2 A;  5JVZ A;  1UZQ A;  1LPZ A;  4NA9 L;  2Y80 B;  3KL6 B;  2BZ6 L;  3N8W A;  2Y5F L;  5JB9 E;  2XC5 L;  2M74 A;  4OTJ A;  2P3F N;  5JB8 E;  3ZYI B;  2GD4 A;  1NFW B;  5IKT A;  3GCW E;  1ATD A;  1IOE L;  1L3Y A;  2Y7X B;  1O5D L;  1K37 A;  1NFX B;  5JBC E;  1F7M A;  2WG3 C;  4A94 C;  2AYL A;  4Y71 B;  3RR3 A;  3TH3 L;  3TZI A;  1EMO A;  2W26 B;  1IQH L;  5IKQ A;  3NTG A;  2P95 L;  2BOU A;  1APO A;  1WHE A;  3LAQ A;  1HRF A;  2FLB L;  2W86 A;  1IOX A;  2H9E L;  3HO3 A;  1IGZ A;  2XC0 L;  2YGP A;  3MDL A;  1IQI L;  3Q3K B;  1FFM A;  1U67 A;  2WPL E;  1IQN L;  4ISH L;  3C9A C;  4YZU B;  1Q4G A;  2BMG A;  3N8Z A;  3OLU A;  1UZK A;  4COX A;  1EMN A;  3DEM A;  2WPM E;  5CKN A;  2W2M E;  4JZF L;  5E8D A;  3CA7 A;  3LC3 B;  2J95 B;  4JZD L;  4XLW A;  1CVU A;  2EI7 B;  4CUD A;  4JYV L;  1IQG L;  2K2S B;  2P93 L;  5F1A A;  3LTF B;  2I9B A;  4M10 A;  3KRK A;  4XBM A;  4LMF A;  1L5G B;  1CCF A;  3FFG L;  3POY A;  2P16 L;  2VVU L;  1OB1 C;  3LN1 A;  1N7D A;  2FLR L;  4X8U L;  3U7U G;  2Y82 B;  2RA0 L;  1KLO A;  3V64 C;  1A3P A;  1ADX A;  2Q1J B;  1HCG B;  1HT8 A;  1PRH A;  2XC4 L;  1J9C L;  1U8C B;  5JVY A;  1KLJ L;  4JZE L;  3BPS E;  4RUT A;  1WHF A;  1XFE A;  1EQG A;  2BQ6 A;  1KIG L;  3HS7 A;  2VH6 B;  1IQJ L;  2KNI A;  2RHP A;  1NFY B;  1FAK L;  4Z0L A;  3SOB B;  2UWP B;  2MGP A;  5I46 L;  2WPH E;  2XBX L;  1W7X L;  3N8W B;  3HS6 A;  3TBD A;  1G1Q A;  1G2M B;  1IQF L;  2J4I B;  2WPI E;  3Q7D A;  1ATA A;  3M37 L;  1DQB A;  2W3I B;  4A7I A;  1URK A;  3M36 L;  4CUF A;  1ZAQ A;  5L2Z L;  2OYE P;  4NG9 L;  1F0S B;  2YGQ A;  3GCX E;  4TGF A;  1DIY A;  1PTH A;  1MQ5 L;  1FF7 A;  2Y81 B;  5KN5 C;  4E1G A;  2FD6 A;  2YGO A;  1PXX A;  1HRE A;  4JYU L;  2PR3 B;  3KCG L;  3MQE A;  1IJQ A;  1IGX A;  4AQT A;  3QMO A;  2W2Q E;  2J38 B;  3KK6 A;  2WPJ E;  3ASI A;  3N8V A;  2TGF A;  2VWM K;  3NJP C;  1NZI A;  4RRW A;  3FBY A;  4CSY A;  3SOQ A;  3GIS X;  4MMY B;  4LOR A;  1EPH A;  1GK5 A;  1TOZ A;  1G1T A;  4Y7B B;  2NPR A;  5K0H B;  1EPG A;  5JW1 A;  1KLI L;  2W2O E;  4NGA L;  3TGF A;  1EBV A;  1PFX L;  2RNL A;  2EI6 B;  3F6U L;  1DDX A;  4O02 B;  5CKQ A;  4BTI A;  2VH0 B;  1IQK L;  3N8Y A;  5L2Y L;  1CX2 A;  2WPK E;  1KSN B;  4X8S L;  3F1S B;  1HT5 A;  3LIW B;  5CKM A;  1ATB A;  4MMZ B;  1FJS L;  4X8V L;  1NT0 A;  1C5M F;  4RRY A;  1TLE A;  3KQC L;  1HAF A;  4Y76 B;  1YUK B;  1UZJ A;  2DDU A;  1P0S L;  2WYG B;  2WFT A;  1DVA L;  2EI8 B;  2K2T A;  2VVV L;  4PH9 A;  2G00 L;  3HS5 A;  1NQL B;  3KQD L;  2FZZ L;  1LPG A;  2P26 A;  4XL1 A;  4ZXY L;  1LPK A;  4ISI L;  3H5C B;  3TK6 B;  1XKA L;  2JKH L;  2W3K B;  1TPG A;  1G1R A;  5COX A;  3LTG D;  3KQE L;  5F19 A;  1EQH A;  4YT7 L;  3HO5 A;  4RS0 A;  1CQE A;  1AUT L;  2Y5H L;  4BTT A;  2CJI B;  1CEJ A;  2BOK L;  1F0R B;  4X8T L;  4C16 A;  1FAX L;  2WZP P;  1NFU B;  2I9A A;  3QH0 A;  3QCW A;  4YT6 L;  5JBA E;  2Y5G L;  2WFX B;  3HPT A;  1LMJ A;  1BF9 A;  2Y7Z B;  1M1X B;  1IQL L;  1HAE A;  2ADX A;  1EZQ B;  2J2U B;  3IJE B;  2UWL B;  3OLT A;  3P5B L;  1Z6C A;  2H9E C;  1JBU L;  2W2N E;  4RRX A;  1ATE A;  1G2L B;  1Z6E L;  2VWO L;  1JV2 B;  4BXW A;  1I0U A;  1EPI A;  3LC5 B;  3N8Y B;  4Z0K B;  3IIT B;  5IKR A;  2F9B L;  1YO8 A;  3BT1 A;  3CFW A;  3S6X A;  4ZAE B;  3HO4 A;  1W8B L;  5EGM B;  1RFN B;  1XDT R;  2J94 B;  5KIR A;  5IKV A;  5JBB E;  2VWN L;  1IQM L;  3NTB A;  2D1J B;  5CIS A;  1FE2 A;  3KQB L;  1APQ A;  1PGE A;  1K36 A;  4Y7A B;  4RRZ A;  2Y38 A;  1DX5 I;  2MHP A;  3PGH A;  2UWO B;  2KB9 A;  1HX2 A;  1V3X B;  1SZB A;  2OYU P;  1YGC L;  1EAI C;  1HJ7 A;  5FDQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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