2VVUL

Aminopyrrolidine factor xa inhibitor
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
54
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHENSVVCSCARGYTLADNGKACIPTGPYPCGKQTLER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 12
structure length 52
sequence length 54
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2008-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2vvuL00
1LPGA 1IQIL 1ZAQA 1MQ5L 1HAFA 3KQEL 3N8XA 4CUDA 1U67A 2WFXB 4M10A 3C9AC 4JZDL 1WHFA 2RA0L 4PH9A 4X8SL 1XDTR 1I0UA 1CCVA 4LMFA 2RNLA 2BO2A 2BOXA 4JYVL 3ENSA 5F19A 1NFXB 3HO5A 1KLIL 1HZ8A 3NTBA 3DEMA 2JKHL 2Y80B 3HS5A 2W2OE 1NQLB 5IKTA 1ATEA 4TGFA 3POYA 1L5GB 1J9CL 3RR3A 1PTHA 2DDUA 1N7DA 1W7XL 2Y7ZB 2K2TA 2UWPB 4CUFA 1C5MF 1FFMA 2P3FN 2VH0B 2VJ3A 4ZXYL 3KQDL 4RRWA 2MGRA 1YGCL 1RFNB 4RS0A 1B9WA 3IJEB 3HS7A 1IQNL 1EPIA 3KQCL 4XL1A 1APQA 3OLTA 1SZBA 1NFYB 2YGOA 1EGFA 3TH3L 2EI8B 4MMZB 2BZ6L 1IVOC 4JYUL 4Y7AB 3LTFB 3Q3KB 4NA9L 1HCGB 1LMJA 5CISA 1OB1C 2NPRA 2XBVL 3ZYIB 2BOUA 2B7DL 2UWLB 3V65B 1COUA 4Y6DB 2Y5HL 3F6UL 2WPIE 3ZYJB 4YT6L 2VWNL 3V64C 1QFKL 2PHBB 3SOQA 4YZUB 2P28B 1CVWL 3LN1A 1G1SA 3KCGL 1LPZA 4D0FA 5JVZA 1P0SL 3KQBL 4D90A 5L2ZL 2Y82B 3TK6B 4NGAL 4XBMA 3FBYA 2TGFA 2FD6A 5IKRA 2J34B 3QH0A 3TK5B 5KIRA 1G2MB 1URKA 5FDQA 1UZJA 3TBDA 2J2UB 3CENL 2F9BL 3N8ZA 3HPTA 3NT1A 4FM5A 1FSBA 1DQBA 1WU1B 1BF9A 4BXSA 1NPEB 1UZPA 1PFXL 2M74A 2Y7XB 4A7IA 5JBCE 6COXA 3ZYGA 2P3UA 4MMXB 1EQGA 1M1XB 2WG4B 5JW1A 1KLOA 3NTGA 3BT2A 1CCFA 1IQKL 2J94B 1FE2A 5JB9E 2BMGA 4E1GA 2BQ6A 5K0HB 3CS7L 2KL7A 2VVVL 1IOEL 2BOHA 4X8VL 2BQWA 4Y7BB 1HRFA 2Y38A 4NG9L 2WYGB 1FJSL 4XLWA 3F1SB 1NFWB 3QCWA 1GK5A 4O1ZA 3FCSB 2XC4L 1APOA 2Q1JB 3LC3B 4ISIL 1YUGA 4BDWA 1MOXC 3OLUA 2FLRL 2J4IB 3FFGL 4ZAEB 2ADXA 5JB8E 1W8BL 1IGZA 1KSNB 1EPHA 1WHEA 4Z0LA 2W2QE 4OTYA 5L30L 2XBXL 1Z6EL 4RRYA 1G1QA 1JL9A 4BTTA 1CEJA 2VVUL 1F0SB 2J38B 2AYLA 2WPME 1EPJA 4ISHL 1JV2B 1IOXA 2WPJE 3BPSE 1ADXA 1IQLL 3M37L 3EGFA 3IITB 1G2LB 4X8TL 2I9BA 4Y71B 1IQEL 1KIGL 4Y76B 1G1TA 3LTGD 1DIYA 5E8DA 1LPKA 3SW2A 2KV4A 2GD4A 2K2SB 5CKQA 2FLGA 3HS6A 1DX5I 1K36A 1CVUA 1L3YA 4CUEA 2XBWL 2WYJB 2UWOB 2PR3B 1ATAA 2VWOL 5CKNA 2P93L 4Y79B 1PXXA 1EZQB 1EBVA 1K37A 1NZIA 1EPGA 1IJQA 3MQEA 4G1MB 2PUQL 4BXWA 1TPGA 5I46L 3N8WA 1EMNA 4BDXA 1UZQA 2OYUP 4JZFL 5CKMA 2P95L 2W2NE 1CX2A 1UZKA 5KN5C 1F0RB 1TOZA 2FLBL 2MHPA 3R05A 2XBYL 2P94L 2Y5GL 1LQDA 2BQ7A 4COXA 2YGPA 1O5DL 3N8YA 2G00L 3ELAL 3SOBB 3TGFA 3QMOA 3N8VA 2P3TA 3P5BL 3KL6B 1ATBA 2P16L 4BTIA 2D1JB 1ATDA 4ZHAB 2I9AA 1IQJL 1HJ7A 5JVYA 4X8UL 3KRKA 3MDLA 2WG3C 1FF7A 1YO8A 1P9JA 1Q4GA 4Z0KB 1EQHA 1IQFL 2Y5FL 1X7AL 1NFUB 3LIWB 1HAEA 3Q7DA 1F7EA 3ASIA 1N1IA 5EGMB 2BOKL 1A3PA 1DVAL 3GCWE 4RRZA 2J95B 5L2YL 3HO3A 1F7MA 3LAQA 1HT8A 2W2ME 2WFTA 2XC0L 5JBBE 1DDXA 1IQGL 4M11A 1IQML 2W3IB 3NJPC 1PRHA 1V3XB 1HT5A 2P26A 5F1AA 4AQTA 2WPKE 1IQHL 3GCXE 3TZIA 3GISX 1Z6CA 3M36L 4Z6AL 2WPHE 3HO4A 1EAIC 5IKVA 1YUFA 3U73A 4LORA 2VWMK 2EI6B 3CFWA 1XFEA 2VH6B 2W86A 1XKBA 4O02B 1YUKB 3U7UG 2H9EL 1U8CB 1AUTL 2W26B 2P3FL 1IP0A 4ZH8B 4ZXXL 3CA7A 3LN0A 2EI7B 1JBUL 3K9XA 2WPLE 1TLEA 3H5CB 1HREA 4BTUA 4CSYA 4YT7L 1CQEA 2KB9A 4RUTA 2OYEP 3SOVA 3PGHA 2MGPA 1PGEA 2XC5L 3N8WB 4OTJA 2CJIB 1KLJL 3LC5B 4C16A 5IKQA 4JZEL 4MMYB 1NT0A 1FAKL 4D0EA 5JBAE 1FAXL 1HX2A 1G1RA 2W3KB 1MQ6L 5COXA 3BT1A 3N8YB 1XKAL 2FZZL 2RHPA 2Y81B 1EMOA 2W2PE 1IGXA 3KK6A 2VWLL 2VVCK 4RRXA
chains in the Genus database with same CATH superfamily
1LPGA 1IQIL 1ZAQA 1MQ5L 1QIUA 1HAFA 3KQEL 3N8XA 4CUDA 1U67A 2WFXB 4M10A 3C9AC 4JZDL 1WHFA 2RA0L 4PH9A 4X8SL 1XDTR 1I0UA 1CCVA 4LMFA 1V1IA 2RNLA 2BO2A 2BOXA 4JYVL 3ENSA 5F19A 1NFXB 3HO5A 1KLIL 1HZ8A 3NTBA 3DEMA 2JKHL 2Y80B 3HS5A 2W2OE 1NQLB 5IKTA 1ATEA 4TGFA 3POYA 1L5GB 1J9CL 3RR3A 1PTHA 2DDUA 1N7DA 1W7XL 2Y7ZB 2K2TA 2UWPB 4CUFA 1LMMA 1C5MF 1FFMA 2P3FN 2VH0B 2VJ3A 4ZXYL 3KQDL 4RRWA 2BT7A 2MGRA 1YGCL 1RFNB 4RS0A 1B9WA 3IJEB 3HS7A 2WZPP 1IQNL 4GU3A 1EPIA 3KQCL 4XL1A 1APQA 3OLTA 1SZBA 1NFYB 2YGOA 1EGFA 3TH3L 2EI8B 4MMZB 2BZ6L 1IVOC 4JYUL 4Y7AB 3LTFB 3Q3KB 4NA9L 1HCGB 1LMJA 5CISA 1OB1C 2NPRA 2XBVL 3ZYIB 2BOUA 2B7DL 2UWLB 3V65B 1COUA 4Y6DB 2Y5HL 3F6UL 2WPIE 3ZYJB 4YT6L 2VWNL 3V64C 1QFKL 2PHBB 3SOQA 4YZUB 2P28B 1CVWL 3LN1A 1G1SA 3KCGL 1LPZA 4D0FA 5JVZA 1P0SL 3KQBL 4D90A 5L2ZL 2Y82B 3TK6B 4NGAL 4GU4A 4XBMA 3FBYA 2TGFA 2FD6A 5IKRA 2J34B 3QH0A 3TK5B 5KIRA 1G2MB 1URKA 5FDQA 1UZJA 3TBDA 2J2UB 3CENL 2F9BL 3N8ZA 3HPTA 3NT1A 2HORA 4FM5A 1FSBA 1DQBA 1WU1B 1BF9A 4BXSA 1NPEB 1UZPA 1PFXL 2M74A 2Y7XB 1LK9A 4A7IA 5JBCE 6COXA 3ZYGA 2P3UA 4MMXB 1EQGA 1M1XB 2WG4B 5JW1A 1KLOA 3NTGA 3BT2A 1CCFA 1IQKL 2J94B 1FE2A 5JB9E 2BMGA 4E1GA 2BQ6A 5K0HB 3CS7L 2KL7A 2VVVL 1IOEL 2BOHA 4A94C 4X8VL 2BQWA 4Y7BB 1HRFA 2Y38A 4NG9L 2WYGB 1FJSL 4XLWA 3F1SB 1NFWB 3QCWA 1GK5A 4O1ZA 3FCSB 2XC4L 1APOA 2Q1JB 3LC3B 4ISIL 1YUGA 4BDWA 1MOXC 3OLUA 2FLRL 2J4IB 3FFGL 4ZAEB 2ADXA 5JB8E 1W8BL 1IGZA 1KSNB 1EPHA 1WHEA 4Z0LA 2W2QE 4OTYA 5L30L 2XBXL 1Z6EL 4RRYA 2HOXA 1G1QA 1JL9A 4BTTA 1CEJA 2VVUL 1F0SB 2J38B 2AYLA 2WPME 1EPJA 4ISHL 1JV2B 1IOXA 2WPJE 3BPSE 1ADXA 1IQLL 3M37L 3EGFA 3IITB 1G2LB 4X8TL 2I9BA 4Y71B 1IQEL 2KNIA 1KIGL 4Y76B 1G1TA 3LTGD 1DIYA 5E8DA 1LPKA 3SW2A 2KV4A 2GD4A 2K2SB 5CKQA 2FLGA 3HS6A 1DX5I 1K36A 1CVUA 1L3YA 4CUEA 2XBWL 2WYJB 2UWOB 2PR3B 1ATAA 2VWOL 5CKNA 2P93L 4Y79B 1PXXA 1EZQB 1EBVA 1K37A 1NZIA 1EPGA 1IJQA 3MQEA 4G1MB 2PUQL 4BXWA 1TPGA 5I46L 3N8WA 1EMNA 4BDXA 1UZQA 2OYUP 4JZFL 5CKMA 2YGQA 2P95L 2W2NE 1CX2A 1UZKA 5KN5C 1F0RB 1TOZA 2FLBL 2MHPA 3R05A 2XBYL 2P94L 2Y5GL 2BT8A 1LQDA 2BQ7A 4COXA 2YGPA 1O5DL 3N8YA 2G00L 3ELAL 3SOBB 3TGFA 3QMOA 3N8VA 2P3TA 3P5BL 3KL6B 1ATBA 2P16L 4BTIA 2D1JB 1ATDA 4ZHAB 2I9AA 1IQJL 1HJ7A 5JVYA 4X8UL 3KRKA 3MDLA 2WG3C 1FF7A 1YO8A 1P9JA 1Q4GA 4Z0KB 1EQHA 1IQFL 2Y5FL 1X7AL 1NFUB 3LIWB 1HAEA 3Q7DA 1F7EA 3ASIA 1N1IA 5EGMB 2BOKL 1A3PA 1DVAL 3GCWE 4RRZA 2J95B 5L2YL 3HO3A 1F7MA 3LAQA 1HT8A 2W2ME 2WFTA 2XC0L 5JBBE 2JJLA 1V1HA 1DDXA 1IQGL 4M11A 1IQML 2W3IB 3NJPC 1PRHA 2VRSA 1V3XB 1HT5A 2P26A 5F1AA 4AQTA 2WPKE 1IQHL 3GCXE 3TZIA 3GISX 1Z6CA 3M36L 4Z6AL 2WPHE 3HO4A 1EAIC 5IKVA 1YUFA 3U73A 4LORA 2VWMK 2EI6B 3CFWA 1XFEA 1KKEA 2VH6B 2W86A 1XKBA 4O02B 1YUKB 3U7UG 2H9EL 1U8CB 2H9EC 1AUTL 2W26B 2P3FL 1IP0A 4ZH8B 4ZXXL 3CA7A 3LN0A 2EI7B 1JBUL 3K9XA 2WPLE 1TLEA 3H5CB 1HREA 4BTUA 4CSYA 4YT7L 1CQEA 2KB9A 4RUTA 2OYEP 3SOVA 3PGHA 2MGPA 1PGEA 2XC5L 3N8WB 2BSFA 4OTJA 2CJIB 1KLJL 3LC5B 4C16A 5IKQA 4JZEL 4MMYB 1NT0A 1FAKL 4D0EA 5JBAE 1FAXL 1HX2A 1G1RA 2W3KB 1MQ6L 3S6XA 5COXA 3BT1A 3N8YB 1XKAL 2FZZL 2RHPA 2Y81B 1EMOA 2W2PE 1IGXA 3KK6A 2VWLL 2VVCK 4RRXA
chains in the Genus database with same CATH topology
1LPGA 1IQIL 1ZAQA 1MQ5L 1HAFA 3KQEL 3N8XA 4CUDA 1U67A 2WFXB 4M10A 3C9AC 4JZDL 1WHFA 2RA0L 4PH9A 4X8SL 1XDTR 1I0UA 1CCVA 4LMFA 2RNLA 2BO2A 2BOXA 4JYVL 3ENSA 5F19A 1NFXB 3HO5A 1KLIL 1HZ8A 3NTBA 3DEMA 2JKHL 2Y80B 3HS5A 2W2OE 1NQLB 5IKTA 1ATEA 4TGFA 3POYA 1L5GB 1J9CL 3RR3A 1PTHA 2DDUA 1N7DA 1W7XL 2Y7ZB 2K2TA 2UWPB 4CUFA 1LMMA 1C5MF 1FFMA 2P3FN 2VH0B 2VJ3A 4ZXYL 3KQDL 4RRWA 2MGRA 1YGCL 1RFNB 4RS0A 1B9WA 3IJEB 3HS7A 2WZPP 1IQNL 1EPIA 3KQCL 4XL1A 1APQA 3OLTA 1SZBA 1NFYB 2YGOA 1EGFA 3TH3L 2EI8B 4MMZB 2BZ6L 1IVOC 4JYUL 4Y7AB 3LTFB 3Q3KB 4NA9L 1HCGB 1LMJA 5CISA 1OB1C 2NPRA 2XBVL 3ZYIB 2BOUA 2B7DL 2UWLB 3V65B 1COUA 4Y6DB 2Y5HL 3F6UL 2WPIE 3ZYJB 4YT6L 2VWNL 3V64C 1QFKL 2PHBB 3SOQA 4YZUB 2P28B 1CVWL 3LN1A 1G1SA 3KCGL 1LPZA 4D0FA 5JVZA 1P0SL 3KQBL 4D90A 5L2ZL 2Y82B 3TK6B 4NGAL 4XBMA 3FBYA 2TGFA 2FD6A 5IKRA 2J34B 3QH0A 3TK5B 5KIRA 1G2MB 1URKA 5FDQA 1UZJA 3TBDA 2J2UB 3CENL 2F9BL 3N8ZA 3HPTA 3NT1A 4FM5A 1FSBA 1DQBA 1WU1B 1BF9A 4BXSA 1NPEB 1UZPA 1PFXL 2M74A 2Y7XB 4A7IA 5JBCE 6COXA 3ZYGA 2P3UA 4MMXB 1EQGA 1M1XB 2WG4B 5JW1A 1KLOA 3NTGA 3BT2A 1CCFA 1IQKL 2J94B 1FE2A 5JB9E 2BMGA 4E1GA 2BQ6A 5K0HB 3CS7L 2KL7A 2VVVL 1IOEL 2BOHA 4A94C 4X8VL 2BQWA 4Y7BB 1HRFA 2Y38A 4NG9L 2WYGB 1FJSL 4XLWA 3F1SB 1NFWB 3QCWA 1GK5A 4O1ZA 3FCSB 2XC4L 1APOA 2Q1JB 3LC3B 4ISIL 1YUGA 4BDWA 1MOXC 3OLUA 2FLRL 2J4IB 3FFGL 4ZAEB 2ADXA 5JB8E 1W8BL 1IGZA 1KSNB 1EPHA 1WHEA 4Z0LA 2W2QE 4OTYA 5L30L 2XBXL 1Z6EL 4RRYA 1G1QA 1JL9A 4BTTA 1CEJA 2VVUL 1F0SB 2J38B 2AYLA 2WPME 1EPJA 4ISHL 1JV2B 1IOXA 2WPJE 3BPSE 1ADXA 1IQLL 3M37L 3EGFA 3IITB 1G2LB 4X8TL 2I9BA 4Y71B 1IQEL 2KNIA 1KIGL 4Y76B 1G1TA 3LTGD 1DIYA 5E8DA 1LPKA 3SW2A 2KV4A 2GD4A 2K2SB 5CKQA 2FLGA 3HS6A 1DX5I 1K36A 1CVUA 1L3YA 4CUEA 2XBWL 2WYJB 2UWOB 2PR3B 1ATAA 2VWOL 5CKNA 2P93L 4Y79B 1PXXA 1EZQB 1EBVA 1K37A 1NZIA 1EPGA 1IJQA 3MQEA 4G1MB 2PUQL 4BXWA 1TPGA 5I46L 3N8WA 1EMNA 4BDXA 1UZQA 2OYUP 4JZFL 5CKMA 2YGQA 2P95L 2W2NE 1CX2A 1UZKA 5KN5C 1F0RB 1TOZA 2FLBL 2MHPA 3R05A 2XBYL 2P94L 2Y5GL 1LQDA 2BQ7A 4COXA 2YGPA 1O5DL 3N8YA 2G00L 3ELAL 3SOBB 3TGFA 3QMOA 3N8VA 2P3TA 3P5BL 3KL6B 1ATBA 2P16L 4BTIA 2D1JB 1ATDA 4ZHAB 2I9AA 1IQJL 1HJ7A 5JVYA 4X8UL 3KRKA 3MDLA 2WG3C 1FF7A 1YO8A 1P9JA 1Q4GA 4Z0KB 1EQHA 1IQFL 2Y5FL 1X7AL 1NFUB 3LIWB 1HAEA 3Q7DA 1F7EA 3ASIA 1N1IA 5EGMB 2BOKL 1A3PA 1DVAL 3GCWE 4RRZA 2J95B 5L2YL 3HO3A 1F7MA 3LAQA 1HT8A 2W2ME 2WFTA 2XC0L 5JBBE 1DDXA 1IQGL 4M11A 1IQML 2W3IB 3NJPC 1PRHA 1V3XB 1HT5A 2P26A 5F1AA 4AQTA 2WPKE 1IQHL 3GCXE 3TZIA 3GISX 1Z6CA 3M36L 4Z6AL 2WPHE 3HO4A 1EAIC 5IKVA 1YUFA 3U73A 4LORA 2VWMK 2EI6B 3CFWA 1XFEA 2VH6B 2W86A 1XKBA 4O02B 1YUKB 3U7UG 2H9EL 1U8CB 2H9EC 1AUTL 2W26B 2P3FL 1IP0A 4ZH8B 4ZXXL 3CA7A 3LN0A 2EI7B 1JBUL 3K9XA 2WPLE 1TLEA 3H5CB 1HREA 4BTUA 4CSYA 4YT7L 1CQEA 2KB9A 4RUTA 2OYEP 3SOVA 3PGHA 2MGPA 1PGEA 2XC5L 3N8WB 4OTJA 2CJIB 1KLJL 3LC5B 4C16A 5IKQA 4JZEL 4MMYB 1NT0A 1FAKL 4D0EA 5JBAE 1FAXL 1HX2A 1G1RA 2W3KB 1MQ6L 3S6XA 5COXA 3BT1A 3N8YB 1XKAL 2FZZL 2RHPA 2Y81B 1EMOA 2W2PE 1IGXA 3KK6A 2VWLL 2VVCK 4RRXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LPG A;  1IQI L;  1ZAQ A;  1MQ5 L;  1HAF A;  3KQE L;  3N8X A;  4CUD A;  1U67 A;  2WFX B;  4M10 A;  3C9A C;  4JZD L;  1WHF A;  2RA0 L;  4PH9 A;  4X8S L;  1XDT R;  1I0U A;  1CCV A;  4LMF A;  2RNL A;  2BO2 A;  2BOX A;  4JYV L;  3ENS A;  5F19 A;  1NFX B;  3HO5 A;  1KLI L;  1HZ8 A;  3NTB A;  3DEM A;  2JKH L;  2Y80 B;  3HS5 A;  2W2O E;  1NQL B;  5IKT A;  1ATE A;  4TGF A;  3POY A;  1L5G B;  1J9C L;  3RR3 A;  1PTH A;  2DDU A;  1N7D A;  1W7X L;  2Y7Z B;  2K2T A;  2UWP B;  4CUF A;  1C5M F;  1FFM A;  2P3F N;  2VH0 B;  2VJ3 A;  4ZXY L;  3KQD L;  4RRW A;  2MGR A;  1YGC L;  1RFN B;  4RS0 A;  1B9W A;  3IJE B;  3HS7 A;  1IQN L;  1EPI A;  3KQC L;  4XL1 A;  1APQ A;  3OLT A;  1SZB A;  1NFY B;  2YGO A;  1EGF A;  3TH3 L;  2EI8 B;  4MMZ B;  2BZ6 L;  1IVO C;  4JYU L;  4Y7A B;  3LTF B;  3Q3K B;  4NA9 L;  1HCG B;  1LMJ A;  5CIS A;  1OB1 C;  2NPR A;  2XBV L;  3ZYI B;  2BOU A;  2B7D L;  2UWL B;  3V65 B;  1COU A;  4Y6D B;  2Y5H L;  3F6U L;  2WPI E;  3ZYJ B;  4YT6 L;  2VWN L;  3V64 C;  1QFK L;  2PHB B;  3SOQ A;  4YZU B;  2P28 B;  1CVW L;  3LN1 A;  1G1S A;  3KCG L;  1LPZ A;  4D0F A;  5JVZ A;  1P0S L;  3KQB L;  4D90 A;  5L2Z L;  2Y82 B;  3TK6 B;  4NGA L;  4XBM A;  3FBY A;  2TGF A;  2FD6 A;  5IKR A;  2J34 B;  3QH0 A;  3TK5 B;  5KIR A;  1G2M B;  1URK A;  5FDQ A;  1UZJ A;  3TBD A;  2J2U B;  3CEN L;  2F9B L;  3N8Z A;  3HPT A;  3NT1 A;  4FM5 A;  1FSB A;  1DQB A;  1WU1 B;  1BF9 A;  4BXS A;  1NPE B;  1UZP A;  1PFX L;  2M74 A;  2Y7X B;  4A7I A;  5JBC E;  6COX A;  3ZYG A;  2P3U A;  4MMX B;  1EQG A;  1M1X B;  2WG4 B;  5JW1 A;  1KLO A;  3NTG A;  3BT2 A;  1CCF A;  1IQK L;  2J94 B;  1FE2 A;  5JB9 E;  2BMG A;  4E1G A;  2BQ6 A;  5K0H B;  3CS7 L;  2KL7 A;  2VVV L;  1IOE L;  2BOH A;  4X8V L;  2BQW A;  4Y7B B;  1HRF A;  2Y38 A;  4NG9 L;  2WYG B;  1FJS L;  4XLW A;  3F1S B;  1NFW B;  3QCW A;  1GK5 A;  4O1Z A;  3FCS B;  2XC4 L;  1APO A;  2Q1J B;  3LC3 B;  4ISI L;  1YUG A;  4BDW A;  1MOX C;  3OLU A;  2FLR L;  2J4I B;  3FFG L;  4ZAE B;  2ADX A;  5JB8 E;  1W8B L;  1IGZ A;  1KSN B;  1EPH A;  1WHE A;  4Z0L A;  2W2Q E;  4OTY A;  5L30 L;  2XBX L;  1Z6E L;  4RRY A;  1G1Q A;  1JL9 A;  4BTT A;  1CEJ A;  2VVU L;  1F0S B;  2J38 B;  2AYL A;  2WPM E;  1EPJ A;  4ISH L;  1JV2 B;  1IOX A;  2WPJ E;  3BPS E;  1ADX A;  1IQL L;  3M37 L;  3EGF A;  3IIT B;  1G2L B;  4X8T L;  2I9B A;  4Y71 B;  1IQE L;  1KIG L;  4Y76 B;  1G1T A;  3LTG D;  1DIY A;  5E8D A;  1LPK A;  3SW2 A;  2KV4 A;  2GD4 A;  2K2S B;  5CKQ A;  2FLG A;  3HS6 A;  1DX5 I;  1K36 A;  1CVU A;  1L3Y A;  4CUE A;  2XBW L;  2WYJ B;  2UWO B;  2PR3 B;  1ATA A;  2VWO L;  5CKN A;  2P93 L;  4Y79 B;  1PXX A;  1EZQ B;  1EBV A;  1K37 A;  1NZI A;  1EPG A;  1IJQ A;  3MQE A;  4G1M B;  2PUQ L;  4BXW A;  1TPG A;  5I46 L;  3N8W A;  1EMN A;  4BDX A;  1UZQ A;  2OYU P;  4JZF L;  5CKM A;  2P95 L;  2W2N E;  1CX2 A;  1UZK A;  5KN5 C;  1F0R B;  1TOZ A;  2FLB L;  2MHP A;  3R05 A;  2XBY L;  2P94 L;  2Y5G L;  1LQD A;  2BQ7 A;  4COX A;  2YGP A;  1O5D L;  3N8Y A;  2G00 L;  3ELA L;  3SOB B;  3TGF A;  3QMO A;  3N8V A;  2P3T A;  3P5B L;  3KL6 B;  1ATB A;  2P16 L;  4BTI A;  2D1J B;  1ATD A;  4ZHA B;  2I9A A;  1IQJ L;  1HJ7 A;  5JVY A;  4X8U L;  3KRK A;  3MDL A;  2WG3 C;  1FF7 A;  1YO8 A;  1P9J A;  1Q4G A;  4Z0K B;  1EQH A;  1IQF L;  2Y5F L;  1X7A L;  1NFU B;  3LIW B;  1HAE A;  3Q7D A;  1F7E A;  3ASI A;  1N1I A;  5EGM B;  2BOK L;  1A3P A;  1DVA L;  3GCW E;  4RRZ A;  2J95 B;  5L2Y L;  3HO3 A;  1F7M A;  3LAQ A;  1HT8 A;  2W2M E;  2WFT A;  2XC0 L;  5JBB E;  1DDX A;  1IQG L;  4M11 A;  1IQM L;  2W3I B;  3NJP C;  1PRH A;  1V3X B;  1HT5 A;  2P26 A;  5F1A A;  4AQT A;  2WPK E;  1IQH L;  3GCX E;  3TZI A;  3GIS X;  1Z6C A;  3M36 L;  4Z6A L;  2WPH E;  3HO4 A;  1EAI C;  5IKV A;  1YUF A;  3U73 A;  4LOR A;  2VWM K;  2EI6 B;  3CFW A;  1XFE A;  2VH6 B;  2W86 A;  1XKB A;  4O02 B;  1YUK B;  3U7U G;  2H9E L;  1U8C B;  1AUT L;  2W26 B;  2P3F L;  1IP0 A;  4ZH8 B;  4ZXX L;  3CA7 A;  3LN0 A;  2EI7 B;  1JBU L;  3K9X A;  2WPL E;  1TLE A;  3H5C B;  1HRE A;  4BTU A;  4CSY A;  4YT7 L;  1CQE A;  2KB9 A;  4RUT A;  2OYE P;  3SOV A;  3PGH A;  2MGP A;  1PGE A;  2XC5 L;  3N8W B;  4OTJ A;  2CJI B;  1KLJ L;  3LC5 B;  4C16 A;  5IKQ A;  4JZE L;  4MMY B;  1NT0 A;  1FAK L;  4D0E A;  5JBA E;  1FAX L;  1HX2 A;  1G1R A;  2W3K B;  1MQ6 L;  5COX A;  3BT1 A;  3N8Y B;  1XKA L;  2FZZ L;  2RHP A;  2Y81 B;  1EMO A;  2W2P E;  1IGX A;  3KK6 A;  2VWL L;  2VVC K;  4RRX A; 
#chains in the Genus database with same CATH topology
 1LPG A;  1IQI L;  1ZAQ A;  1MQ5 L;  1QIU A;  1HAF A;  3KQE L;  3N8X A;  4CUD A;  1U67 A;  2WFX B;  4M10 A;  3C9A C;  4JZD L;  1WHF A;  2RA0 L;  4PH9 A;  4X8S L;  1XDT R;  1I0U A;  1CCV A;  4LMF A;  1V1I A;  2RNL A;  2BO2 A;  2BOX A;  4JYV L;  3ENS A;  5F19 A;  1NFX B;  3HO5 A;  1KLI L;  1HZ8 A;  3NTB A;  3DEM A;  2JKH L;  2Y80 B;  3HS5 A;  2W2O E;  1NQL B;  5IKT A;  1ATE A;  4TGF A;  3POY A;  1L5G B;  1J9C L;  3RR3 A;  1PTH A;  2DDU A;  1N7D A;  1W7X L;  2Y7Z B;  2K2T A;  2UWP B;  4CUF A;  1LMM A;  1C5M F;  1FFM A;  2P3F N;  2VH0 B;  2VJ3 A;  4ZXY L;  3KQD L;  4RRW A;  2BT7 A;  2MGR A;  1YGC L;  1RFN B;  4RS0 A;  1B9W A;  3IJE B;  3HS7 A;  2WZP P;  1IQN L;  4GU3 A;  1EPI A;  3KQC L;  4XL1 A;  1APQ A;  3OLT A;  1SZB A;  1NFY B;  2YGO A;  1EGF A;  3TH3 L;  2EI8 B;  4MMZ B;  2BZ6 L;  1IVO C;  4JYU L;  4Y7A B;  3LTF B;  3Q3K B;  4NA9 L;  1HCG B;  1LMJ A;  5CIS A;  1OB1 C;  2NPR A;  2XBV L;  3ZYI B;  2BOU A;  2B7D L;  2UWL B;  3V65 B;  1COU A;  4Y6D B;  2Y5H L;  3F6U L;  2WPI E;  3ZYJ B;  4YT6 L;  2VWN L;  3V64 C;  1QFK L;  2PHB B;  3SOQ A;  4YZU B;  2P28 B;  1CVW L;  3LN1 A;  1G1S A;  3KCG L;  1LPZ A;  4D0F A;  5JVZ A;  1P0S L;  3KQB L;  4D90 A;  5L2Z L;  2Y82 B;  3TK6 B;  4NGA L;  4GU4 A;  4XBM A;  3FBY A;  2TGF A;  2FD6 A;  5IKR A;  2J34 B;  3QH0 A;  3TK5 B;  5KIR A;  1G2M B;  1URK A;  5FDQ A;  1UZJ A;  3TBD A;  2J2U B;  3CEN L;  2F9B L;  3N8Z A;  3HPT A;  3NT1 A;  2HOR A;  4FM5 A;  1FSB A;  1DQB A;  1WU1 B;  1BF9 A;  4BXS A;  1NPE B;  1UZP A;  1PFX L;  2M74 A;  2Y7X B;  1LK9 A;  4A7I A;  5JBC E;  6COX A;  3ZYG A;  2P3U A;  4MMX B;  1EQG A;  1M1X B;  2WG4 B;  5JW1 A;  1KLO A;  3NTG A;  3BT2 A;  1CCF A;  1IQK L;  2J94 B;  1FE2 A;  5JB9 E;  2BMG A;  4E1G A;  2BQ6 A;  5K0H B;  3CS7 L;  2KL7 A;  2VVV L;  1IOE L;  2BOH A;  4A94 C;  4X8V L;  2BQW A;  4Y7B B;  1HRF A;  2Y38 A;  4NG9 L;  2WYG B;  1FJS L;  4XLW A;  3F1S B;  1NFW B;  3QCW A;  1GK5 A;  4O1Z A;  3FCS B;  2XC4 L;  1APO A;  2Q1J B;  3LC3 B;  4ISI L;  1YUG A;  4BDW A;  1MOX C;  3OLU A;  2FLR L;  2J4I B;  3FFG L;  4ZAE B;  2ADX A;  5JB8 E;  1W8B L;  1IGZ A;  1KSN B;  1EPH A;  1WHE A;  4Z0L A;  2W2Q E;  4OTY A;  5L30 L;  2XBX L;  1Z6E L;  4RRY A;  2HOX A;  1G1Q A;  1JL9 A;  4BTT A;  1CEJ A;  2VVU L;  1F0S B;  2J38 B;  2AYL A;  2WPM E;  1EPJ A;  4ISH L;  1JV2 B;  1IOX A;  2WPJ E;  3BPS E;  1ADX A;  1IQL L;  3M37 L;  3EGF A;  3IIT B;  1G2L B;  4X8T L;  2I9B A;  4Y71 B;  1IQE L;  2KNI A;  1KIG L;  4Y76 B;  1G1T A;  3LTG D;  1DIY A;  5E8D A;  1LPK A;  3SW2 A;  2KV4 A;  2GD4 A;  2K2S B;  5CKQ A;  2FLG A;  3HS6 A;  1DX5 I;  1K36 A;  1CVU A;  1L3Y A;  4CUE A;  2XBW L;  2WYJ B;  2UWO B;  2PR3 B;  1ATA A;  2VWO L;  5CKN A;  2P93 L;  4Y79 B;  1PXX A;  1EZQ B;  1EBV A;  1K37 A;  1NZI A;  1EPG A;  1IJQ A;  3MQE A;  4G1M B;  2PUQ L;  4BXW A;  1TPG A;  5I46 L;  3N8W A;  1EMN A;  4BDX A;  1UZQ A;  2OYU P;  4JZF L;  5CKM A;  2YGQ A;  2P95 L;  2W2N E;  1CX2 A;  1UZK A;  5KN5 C;  1F0R B;  1TOZ A;  2FLB L;  2MHP A;  3R05 A;  2XBY L;  2P94 L;  2Y5G L;  2BT8 A;  1LQD A;  2BQ7 A;  4COX A;  2YGP A;  1O5D L;  3N8Y A;  2G00 L;  3ELA L;  3SOB B;  3TGF A;  3QMO A;  3N8V A;  2P3T A;  3P5B L;  3KL6 B;  1ATB A;  2P16 L;  4BTI A;  2D1J B;  1ATD A;  4ZHA B;  2I9A A;  1IQJ L;  1HJ7 A;  5JVY A;  4X8U L;  3KRK A;  3MDL A;  2WG3 C;  1FF7 A;  1YO8 A;  1P9J A;  1Q4G A;  4Z0K B;  1EQH A;  1IQF L;  2Y5F L;  1X7A L;  1NFU B;  3LIW B;  1HAE A;  3Q7D A;  1F7E A;  3ASI A;  1N1I A;  5EGM B;  2BOK L;  1A3P A;  1DVA L;  3GCW E;  4RRZ A;  2J95 B;  5L2Y L;  3HO3 A;  1F7M A;  3LAQ A;  1HT8 A;  2W2M E;  2WFT A;  2XC0 L;  5JBB E;  2JJL A;  1V1H A;  1DDX A;  1IQG L;  4M11 A;  1IQM L;  2W3I B;  3NJP C;  1PRH A;  2VRS A;  1V3X B;  1HT5 A;  2P26 A;  5F1A A;  4AQT A;  2WPK E;  1IQH L;  3GCX E;  3TZI A;  3GIS X;  1Z6C A;  3M36 L;  4Z6A L;  2WPH E;  3HO4 A;  1EAI C;  5IKV A;  1YUF A;  3U73 A;  4LOR A;  2VWM K;  2EI6 B;  3CFW A;  1XFE A;  1KKE A;  2VH6 B;  2W86 A;  1XKB A;  4O02 B;  1YUK B;  3U7U G;  2H9E L;  1U8C B;  2H9E C;  1AUT L;  2W26 B;  2P3F L;  1IP0 A;  4ZH8 B;  4ZXX L;  3CA7 A;  3LN0 A;  2EI7 B;  1JBU L;  3K9X A;  2WPL E;  1TLE A;  3H5C B;  1HRE A;  4BTU A;  4CSY A;  4YT7 L;  1CQE A;  2KB9 A;  4RUT A;  2OYE P;  3SOV A;  3PGH A;  2MGP A;  1PGE A;  2XC5 L;  3N8W B;  2BSF A;  4OTJ A;  2CJI B;  1KLJ L;  3LC5 B;  4C16 A;  5IKQ A;  4JZE L;  4MMY B;  1NT0 A;  1FAK L;  4D0E A;  5JBA E;  1FAX L;  1HX2 A;  1G1R A;  2W3K B;  1MQ6 L;  3S6X A;  5COX A;  3BT1 A;  3N8Y B;  1XKA L;  2FZZ L;  2RHP A;  2Y81 B;  1EMO A;  2W2P E;  1IGX A;  3KK6 A;  2VWL L;  2VVC K;  4RRX A; 
#chains in the Genus database with same CATH homology
 1LPG A;  1IQI L;  1ZAQ A;  1MQ5 L;  1HAF A;  3KQE L;  3N8X A;  4CUD A;  1U67 A;  2WFX B;  4M10 A;  3C9A C;  4JZD L;  1WHF A;  2RA0 L;  4PH9 A;  4X8S L;  1XDT R;  1I0U A;  1CCV A;  4LMF A;  2RNL A;  2BO2 A;  2BOX A;  4JYV L;  3ENS A;  5F19 A;  1NFX B;  3HO5 A;  1KLI L;  1HZ8 A;  3NTB A;  3DEM A;  2JKH L;  2Y80 B;  3HS5 A;  2W2O E;  1NQL B;  5IKT A;  1ATE A;  4TGF A;  3POY A;  1L5G B;  1J9C L;  3RR3 A;  1PTH A;  2DDU A;  1N7D A;  1W7X L;  2Y7Z B;  2K2T A;  2UWP B;  4CUF A;  1LMM A;  1C5M F;  1FFM A;  2P3F N;  2VH0 B;  2VJ3 A;  4ZXY L;  3KQD L;  4RRW A;  2MGR A;  1YGC L;  1RFN B;  4RS0 A;  1B9W A;  3IJE B;  3HS7 A;  2WZP P;  1IQN L;  1EPI A;  3KQC L;  4XL1 A;  1APQ A;  3OLT A;  1SZB A;  1NFY B;  2YGO A;  1EGF A;  3TH3 L;  2EI8 B;  4MMZ B;  2BZ6 L;  1IVO C;  4JYU L;  4Y7A B;  3LTF B;  3Q3K B;  4NA9 L;  1HCG B;  1LMJ A;  5CIS A;  1OB1 C;  2NPR A;  2XBV L;  3ZYI B;  2BOU A;  2B7D L;  2UWL B;  3V65 B;  1COU A;  4Y6D B;  2Y5H L;  3F6U L;  2WPI E;  3ZYJ B;  4YT6 L;  2VWN L;  3V64 C;  1QFK L;  2PHB B;  3SOQ A;  4YZU B;  2P28 B;  1CVW L;  3LN1 A;  1G1S A;  3KCG L;  1LPZ A;  4D0F A;  5JVZ A;  1P0S L;  3KQB L;  4D90 A;  5L2Z L;  2Y82 B;  3TK6 B;  4NGA L;  4XBM A;  3FBY A;  2TGF A;  2FD6 A;  5IKR A;  2J34 B;  3QH0 A;  3TK5 B;  5KIR A;  1G2M B;  1URK A;  5FDQ A;  1UZJ A;  3TBD A;  2J2U B;  3CEN L;  2F9B L;  3N8Z A;  3HPT A;  3NT1 A;  4FM5 A;  1FSB A;  1DQB A;  1WU1 B;  1BF9 A;  4BXS A;  1NPE B;  1UZP A;  1PFX L;  2M74 A;  2Y7X B;  4A7I A;  5JBC E;  6COX A;  3ZYG A;  2P3U A;  4MMX B;  1EQG A;  1M1X B;  2WG4 B;  5JW1 A;  1KLO A;  3NTG A;  3BT2 A;  1CCF A;  1IQK L;  2J94 B;  1FE2 A;  5JB9 E;  2BMG A;  4E1G A;  2BQ6 A;  5K0H B;  3CS7 L;  2KL7 A;  2VVV L;  1IOE L;  2BOH A;  4A94 C;  4X8V L;  2BQW A;  4Y7B B;  1HRF A;  2Y38 A;  4NG9 L;  2WYG B;  1FJS L;  4XLW A;  3F1S B;  1NFW B;  3QCW A;  1GK5 A;  4O1Z A;  3FCS B;  2XC4 L;  1APO A;  2Q1J B;  3LC3 B;  4ISI L;  1YUG A;  4BDW A;  1MOX C;  3OLU A;  2FLR L;  2J4I B;  3FFG L;  4ZAE B;  2ADX A;  5JB8 E;  1W8B L;  1IGZ A;  1KSN B;  1EPH A;  1WHE A;  4Z0L A;  2W2Q E;  4OTY A;  5L30 L;  2XBX L;  1Z6E L;  4RRY A;  1G1Q A;  1JL9 A;  4BTT A;  1CEJ A;  2VVU L;  1F0S B;  2J38 B;  2AYL A;  2WPM E;  1EPJ A;  4ISH L;  1JV2 B;  1IOX A;  2WPJ E;  3BPS E;  1ADX A;  1IQL L;  3M37 L;  3EGF A;  3IIT B;  1G2L B;  4X8T L;  2I9B A;  4Y71 B;  1IQE L;  2KNI A;  1KIG L;  4Y76 B;  1G1T A;  3LTG D;  1DIY A;  5E8D A;  1LPK A;  3SW2 A;  2KV4 A;  2GD4 A;  2K2S B;  5CKQ A;  2FLG A;  3HS6 A;  1DX5 I;  1K36 A;  1CVU A;  1L3Y A;  4CUE A;  2XBW L;  2WYJ B;  2UWO B;  2PR3 B;  1ATA A;  2VWO L;  5CKN A;  2P93 L;  4Y79 B;  1PXX A;  1EZQ B;  1EBV A;  1K37 A;  1NZI A;  1EPG A;  1IJQ A;  3MQE A;  4G1M B;  2PUQ L;  4BXW A;  1TPG A;  5I46 L;  3N8W A;  1EMN A;  4BDX A;  1UZQ A;  2OYU P;  4JZF L;  5CKM A;  2YGQ A;  2P95 L;  2W2N E;  1CX2 A;  1UZK A;  5KN5 C;  1F0R B;  1TOZ A;  2FLB L;  2MHP A;  3R05 A;  2XBY L;  2P94 L;  2Y5G L;  1LQD A;  2BQ7 A;  4COX A;  2YGP A;  1O5D L;  3N8Y A;  2G00 L;  3ELA L;  3SOB B;  3TGF A;  3QMO A;  3N8V A;  2P3T A;  3P5B L;  3KL6 B;  1ATB A;  2P16 L;  4BTI A;  2D1J B;  1ATD A;  4ZHA B;  2I9A A;  1IQJ L;  1HJ7 A;  5JVY A;  4X8U L;  3KRK A;  3MDL A;  2WG3 C;  1FF7 A;  1YO8 A;  1P9J A;  1Q4G A;  4Z0K B;  1EQH A;  1IQF L;  2Y5F L;  1X7A L;  1NFU B;  3LIW B;  1HAE A;  3Q7D A;  1F7E A;  3ASI A;  1N1I A;  5EGM B;  2BOK L;  1A3P A;  1DVA L;  3GCW E;  4RRZ A;  2J95 B;  5L2Y L;  3HO3 A;  1F7M A;  3LAQ A;  1HT8 A;  2W2M E;  2WFT A;  2XC0 L;  5JBB E;  1DDX A;  1IQG L;  4M11 A;  1IQM L;  2W3I B;  3NJP C;  1PRH A;  1V3X B;  1HT5 A;  2P26 A;  5F1A A;  4AQT A;  2WPK E;  1IQH L;  3GCX E;  3TZI A;  3GIS X;  1Z6C A;  3M36 L;  4Z6A L;  2WPH E;  3HO4 A;  1EAI C;  5IKV A;  1YUF A;  3U73 A;  4LOR A;  2VWM K;  2EI6 B;  3CFW A;  1XFE A;  2VH6 B;  2W86 A;  1XKB A;  4O02 B;  1YUK B;  3U7U G;  2H9E L;  1U8C B;  2H9E C;  1AUT L;  2W26 B;  2P3F L;  1IP0 A;  4ZH8 B;  4ZXX L;  3CA7 A;  3LN0 A;  2EI7 B;  1JBU L;  3K9X A;  2WPL E;  1TLE A;  3H5C B;  1HRE A;  4BTU A;  4CSY A;  4YT7 L;  1CQE A;  2KB9 A;  4RUT A;  2OYE P;  3SOV A;  3PGH A;  2MGP A;  1PGE A;  2XC5 L;  3N8W B;  4OTJ A;  2CJI B;  1KLJ L;  3LC5 B;  4C16 A;  5IKQ A;  4JZE L;  4MMY B;  1NT0 A;  1FAK L;  4D0E A;  5JBA E;  1FAX L;  1HX2 A;  1G1R A;  2W3K B;  1MQ6 L;  3S6X A;  5COX A;  3BT1 A;  3N8Y B;  1XKA L;  2FZZ L;  2RHP A;  2Y81 B;  1EMO A;  2W2P E;  1IGX A;  3KK6 A;  2VWL L;  2VVC K;  4RRX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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