2VWNL

Aminopyrrolidine factor xa inhibitor
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
51
structure length
44
Chain Sequence
LCSLDNGDCDQFCHEVVCSCARGYTLAKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 10
structure length 44
sequence length 51
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2008-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2vwnL00
4ZAEB 2EI6B 2MHPA 1IQFL 3NTBA 4XL1A 1LPZA 1L3YA 3SOVA 2J34B 1KIGL 3LC5B 1DQBA 5K0HB 5IKTA 4JYUL 2FLRL 5KN5C 1FAKL 1NQLB 3KK6A 2J2UB 5FDQA 1CVUA 4Y7BB 1YGCL 3K9XA 3C9AC 4CUDA 1IQEL 1ATBA 5JVZA 5IKVA 5IKRA 2J4IB 2K2SB 1EPGA 5IKQA 3KQDL 4OTYA 4RRZA 4TGFA 1FF7A 4Y76B 4NGAL 2VH6B 3TK6B 3PGHA 5KIRA 1XDTR 2Y38A 2P3FL 5EGMB 4BXSA 2RHPA 3NJPC 2VVCK 3SOQA 1P0SL 3NT1A 4LORA 5JBBE 5CKQA 1LPKA 3DEMA 1MQ6L 1U8CB 4AQTA 1APQA 1W8BL 1XFEA 4NG9L 3QCWA 2EI8B 1K37A 2VH0B 2OYUP 2PHBB 2XBWL 2WPJE 2BQWA 1B9WA 2VWOL 1IQJL 2W86A 1Z6EL 4Z6AL 4G1MB 3HO4A 3ENSA 4A7IA 3CS7L 3HS5A 1TOZA 1SZBA 1IP0A 3GCWE 4MMZB 1IQKL 3BT1A 4XBMA 3TGFA 1HX2A 2VWMK 3MQEA 3ZYIB 1IQNL 2BZ6L 3OLTA 5L2ZL 1FE2A 2WPHE 2Y7ZB 3NTGA 2Y80B 1F0SB 1YUGA 3IITB 3N8VA 1IQIL 1CVWL 4CUEA 2F9BL 3Q3KB 4D0EA 5F1AA 1WU1B 2G00L 3KL6B 3IJEB 1NFWB 3EGFA 3FCSB 3KCGL 1DVAL 1JV2B 1G1SA 1EGFA 1LPGA 1KSNB 2P28B 1HJ7A 5CKNA 2Y5GL 5JB8E 2WG3C 1XKAL 1FAXL 1F7MA 1KLIL 1WHFA 2WFTA 1UZKA 1F7EA 3N8ZA 3TK5B 4RS0A 1EMOA 5F19A 1UZQA 2KV4A 1G1TA 1EPJA 2WPLE 4ZXXL 1COUA 2J95B 1KLJL 2TGFA 1UZJA 1URKA 3P5BL 4C16A 1IQHL 2NPRA 1HRFA 2VWNL 1O5DL 5CKMA 3N8YB 3KQEL 3POYA 1FSBA 3GISX 1UZPA 2EI7B 3ZYJB 4Y71B 4X8VL 1IGXA 4BTTA 2XBYL 2GD4A 3ELAL 1MOXC 2XBVL 1G1QA 2W2ME 3KRKA 1Q4GA 1G1RA 1C5MF 2P95L 4XLWA 1LMJA 1FJSL 1HREA 3FBYA 1V3XB 2W3KB 2XC5L 1EQHA 1EPHA 1RFNB 4X8TL 3U73A 2UWPB 2P3FN 1LQDA 3LC3B 2PUQL 2D1JB 2VVUL 2Y7XB 4ISIL 2P16L 4RRYA 1F0RB 1PGEA 2AYLA 4Y79B 1A3PA 1GK5A 2UWLB 1NZIA 1W7XL 1L5GB 3RR3A 2P94L 2WPKE 1Z6CA 4ZH8B 1NT0A 2W2NE 3GCXE 1ADXA 1N7DA 1YUKB 2FLBL 2WG4B 4E1GA 1M1XB 2P93L 2FZZL 1N1IA 3U7UG 2BOUA 5I46L 2I9AA 1G2MB 2BOKL 3M37L 1IOEL 4RRXA 3HPTA 2J38B 2XC4L 1TLEA 1YO8A 1EAIC 4BDXA 1OB1C 1DDXA 2XBXL 6COXA 1IQLL 4D90A 2FLGA 5COXA 3TBDA 2WPIE 1G2LB 4JZDL 2BMGA 2Y5HL 2BOHA 4RUTA 4YZUB 1KLOA 4O1ZA 1XKBA 4ZHAB 2VJ3A 3TZIA 4O02B 3LIWB 2MGRA 2Q1JB 1CQEA 1QFKL 1NFUB 3BT2A 3ASIA 4COXA 1NFXB 1IVOC 2MGPA 3TH3L 2W2QE 2W3IB 1EBVA 2KB9A 1JL9A 3Q7DA 3CFWA 4BDWA 3F1SB 2W26B 1EMNA 4Z0LA 2WPME 1AUTL 4M11A 1EPIA 2FD6A 2K2TA 3N8XA 1P9JA 3CA7A 3CENL 2VVVL 1HZ8A 1ATAA 1PTHA 3V64C 2Y82B 4FM5A 5L30L 3BPSE 3LN1A 1IQML 1MQ5L 1DIYA 1CCFA 1PFXL 2Y81B 4BXWA 1ATDA 1YUFA 3QH0A 2YGPA 4PH9A 2I9BA 1NPEB 3N8WA 5L2YL 5JBCE 2W2OE 4JZFL 1IJQA 1PXXA 5CISA 1FFMA 1HAFA 1EQGA 1CCVA 3SW2A 3ZYGA 4YT7L 4JYVL 2BQ7A 2P26A 4ZXYL 3FFGL 2BQ6A 3HO5A 1X7AL 2ADXA 5JBAE 1BF9A 3KQBL 4MMXB 2CJIB 1ZAQA 1NFYB 3F6UL 3H5CB 3SOBB 4LMFA 1HT8A 4BTIA 1HT5A 1IQGL 2M74A 2B7DL 1K36A 3HS7A 2PR3B 2BO2A 4D0FA 5E8DA 2UWOB 4CSYA 1HAEA 2RNLA 2J94B 2KL7A 3KQCL 3V65B 2OYEP 1WHEA 2BOXA 3LTGD 1ATEA 3N8WB 1J9CL 1DX5I 2W2PE 3MDLA 4ISHL 4Y7AB 1IGZA 2YGOA 2H9EL 3LTFB 4Z0KB 4RRWA 1JBUL 2DDUA 2RA0L 1CEJA 2WFXB 3OLUA 1EZQB 4M10A 5JVYA 4Y6DB 4OTJA 3HS6A 1APOA 3M36L 3LN0A 3QMOA 3R05A 1PRHA 1TPGA 4NA9L 1U67A 3HO3A 5JW1A 2P3TA 3LAQA 5JB9E 2Y5FL 2WYJB 1HCGB 4X8SL 2VWLL 3N8YA 4MMYB 1I0UA 4X8UL 2XC0L 2JKHL 4CUFA 1IOXA 4YT6L 4BTUA 2WYGB 1CX2A 4JZEL 2P3UA
chains in the Genus database with same CATH superfamily
1QIUA 4ZAEB 2EI6B 2MHPA 1IQFL 3NTBA 4XL1A 1LPZA 1L3YA 3SOVA 2J34B 1KIGL 3LC5B 1DQBA 5K0HB 2HOXA 5IKTA 4JYUL 2FLRL 4GU4A 5KN5C 1FAKL 1NQLB 3KK6A 2J2UB 5FDQA 1CVUA 4Y7BB 1YGCL 3K9XA 3C9AC 4CUDA 1IQEL 1ATBA 5JVZA 5IKVA 5IKRA 2J4IB 2K2SB 1EPGA 5IKQA 3KQDL 4OTYA 4RRZA 4TGFA 1FF7A 4Y76B 4NGAL 2VH6B 3TK6B 3PGHA 5KIRA 1XDTR 2Y38A 2P3FL 5EGMB 4BXSA 2RHPA 3NJPC 2VVCK 3SOQA 1P0SL 3NT1A 4LORA 5JBBE 5CKQA 1LPKA 3DEMA 1MQ6L 1U8CB 4AQTA 1APQA 1W8BL 1XFEA 4NG9L 3QCWA 2EI8B 1K37A 2VH0B 2OYUP 2PHBB 2XBWL 2WPJE 2BQWA 1B9WA 2VWOL 1IQJL 2W86A 2WZPP 1Z6EL 4Z6AL 4G1MB 3HO4A 3ENSA 4A7IA 3CS7L 3HS5A 1TOZA 1SZBA 1IP0A 3GCWE 4MMZB 1IQKL 3BT1A 4XBMA 3TGFA 1HX2A 2VWMK 3MQEA 3ZYIB 1IQNL 2BT7A 2BZ6L 3OLTA 5L2ZL 1FE2A 2WPHE 2BT8A 2Y7ZB 2Y80B 3NTGA 1F0SB 1YUGA 3IITB 3N8VA 1IQIL 1CVWL 4CUEA 2F9BL 3Q3KB 4D0EA 5F1AA 1WU1B 2G00L 3KL6B 3IJEB 1NFWB 3EGFA 2BSFA 3FCSB 3KCGL 1DVAL 1JV2B 1G1SA 1EGFA 1LPGA 1KSNB 2P28B 1HJ7A 2HORA 5CKNA 2Y5GL 5JB8E 2WG3C 1XKAL 1FAXL 1F7MA 1LK9A 1KLIL 1WHFA 2WFTA 1UZKA 1F7EA 3N8ZA 3TK5B 4RS0A 1EMOA 5F19A 1UZQA 2KV4A 1G1TA 1EPJA 2WPLE 4ZXXL 1COUA 2J95B 1KLJL 2TGFA 1UZJA 1URKA 3P5BL 4C16A 1IQHL 2NPRA 1HRFA 2VWNL 1O5DL 5CKMA 3N8YB 3KQEL 3POYA 1FSBA 3GISX 1UZPA 2EI7B 3ZYJB 4Y71B 4X8VL 1IGXA 4BTTA 2XBYL 2GD4A 3ELAL 1MOXC 2XBVL 1G1QA 2W2ME 3KRKA 1Q4GA 1G1RA 1C5MF 2P95L 4XLWA 1LMJA 1FJSL 1HREA 3FBYA 1V3XB 2W3KB 2XC5L 1EQHA 1EPHA 1RFNB 4X8TL 3U73A 2UWPB 2P3FN 1LQDA 3LC3B 2PUQL 2D1JB 2YGQA 2VVUL 2Y7XB 4ISIL 2P16L 4RRYA 1F0RB 1PGEA 2AYLA 4Y79B 1A3PA 1GK5A 1V1HA 2UWLB 1NZIA 1W7XL 1L5GB 3RR3A 2P94L 2WPKE 1Z6CA 4ZH8B 1NT0A 2W2NE 3GCXE 1ADXA 1N7DA 1YUKB 2FLBL 2WG4B 4E1GA 1M1XB 2P93L 2FZZL 1N1IA 3U7UG 2BOUA 5I46L 2I9AA 1G2MB 2BOKL 3M37L 1IOEL 4RRXA 3HPTA 2J38B 2XC4L 1TLEA 1YO8A 2VRSA 1EAIC 4BDXA 1OB1C 1DDXA 2XBXL 2JJLA 6COXA 1IQLL 4D90A 2FLGA 5COXA 3TBDA 2WPIE 1G2LB 4JZDL 2BMGA 2Y5HL 2BOHA 4RUTA 4YZUB 1KLOA 4O1ZA 1XKBA 4ZHAB 2VJ3A 3TZIA 4O02B 3LIWB 2MGRA 2Q1JB 1CQEA 1QFKL 1NFUB 3BT2A 3ASIA 4COXA 1NFXB 1IVOC 2MGPA 3TH3L 2W2QE 2W3IB 1EBVA 2KB9A 1JL9A 3Q7DA 3CFWA 4BDWA 3F1SB 2W26B 1EMNA 4Z0LA 2WPME 1AUTL 4M11A 1EPIA 2FD6A 2K2TA 3N8XA 1P9JA 3CA7A 3CENL 2VVVL 1HZ8A 1ATAA 1PTHA 3V64C 2Y82B 4FM5A 3S6XA 1V1IA 5L30L 3BPSE 3LN1A 1IQML 1MQ5L 1DIYA 1CCFA 1PFXL 2Y81B 4BXWA 1ATDA 1YUFA 3QH0A 1LMMA 2YGPA 4PH9A 2I9BA 1NPEB 3N8WA 5L2YL 5JBCE 2W2OE 4JZFL 1IJQA 1PXXA 5CISA 1FFMA 1HAFA 1EQGA 4GU3A 1CCVA 3SW2A 3ZYGA 4YT7L 4JYVL 2BQ7A 2P26A 4ZXYL 3FFGL 2BQ6A 3HO5A 1X7AL 2ADXA 5JBAE 1BF9A 3KQBL 4MMXB 2CJIB 1ZAQA 1NFYB 3F6UL 3H5CB 3SOBB 4LMFA 1HT8A 4BTIA 1HT5A 1IQGL 2M74A 2B7DL 1K36A 3HS7A 2PR3B 2BO2A 4D0FA 5E8DA 2UWOB 4CSYA 1HAEA 2RNLA 2J94B 2KL7A 3KQCL 3V65B 2OYEP 1WHEA 2BOXA 3LTGD 1ATEA 2H9EC 3N8WB 1J9CL 1DX5I 2W2PE 3MDLA 4ISHL 4Y7AB 1IGZA 2YGOA 2H9EL 3LTFB 2KNIA 4Z0KB 4RRWA 1JBUL 2DDUA 2RA0L 1CEJA 2WFXB 3OLUA 1EZQB 4M10A 4A94C 5JVYA 4Y6DB 4OTJA 3HS6A 1APOA 1KKEA 3M36L 3LN0A 3QMOA 3R05A 1PRHA 1TPGA 4NA9L 1U67A 3HO3A 5JW1A 2P3TA 3LAQA 5JB9E 2Y5FL 2WYJB 1HCGB 4X8SL 2VWLL 3N8YA 4MMYB 1I0UA 4X8UL 2XC0L 2JKHL 4CUFA 1IOXA 4YT6L 4BTUA 2WYGB 1CX2A 4JZEL 2P3UA
chains in the Genus database with same CATH topology
4ZAEB 2EI6B 2MHPA 1IQFL 3NTBA 4XL1A 1LPZA 1L3YA 3SOVA 2J34B 1KIGL 3LC5B 1DQBA 5K0HB 5IKTA 4JYUL 2FLRL 5KN5C 1FAKL 1NQLB 3KK6A 2J2UB 5FDQA 1CVUA 4Y7BB 1YGCL 3K9XA 3C9AC 4CUDA 1IQEL 1ATBA 5JVZA 5IKVA 5IKRA 2J4IB 2K2SB 1EPGA 5IKQA 3KQDL 4OTYA 4RRZA 4TGFA 1FF7A 4Y76B 4NGAL 2VH6B 3TK6B 3PGHA 5KIRA 1XDTR 2Y38A 2P3FL 5EGMB 4BXSA 2RHPA 3NJPC 2VVCK 3SOQA 1P0SL 3NT1A 4LORA 5JBBE 5CKQA 1LPKA 3DEMA 1MQ6L 1U8CB 4AQTA 1APQA 1W8BL 1XFEA 4NG9L 3QCWA 2EI8B 1K37A 2VH0B 2OYUP 2PHBB 2XBWL 2WPJE 2BQWA 1B9WA 2VWOL 1IQJL 2W86A 2WZPP 1Z6EL 4Z6AL 4G1MB 3HO4A 3ENSA 4A7IA 3CS7L 3HS5A 1TOZA 1SZBA 1IP0A 3GCWE 4MMZB 1IQKL 3BT1A 4XBMA 3TGFA 1HX2A 2VWMK 3MQEA 3ZYIB 1IQNL 2BZ6L 3OLTA 5L2ZL 1FE2A 2WPHE 2Y7ZB 3NTGA 2Y80B 1F0SB 1YUGA 3IITB 3N8VA 1IQIL 1CVWL 4CUEA 2F9BL 3Q3KB 4D0EA 5F1AA 1WU1B 2G00L 3KL6B 3IJEB 1NFWB 3EGFA 3FCSB 3KCGL 1DVAL 1JV2B 1G1SA 1EGFA 1LPGA 1KSNB 2P28B 1HJ7A 5CKNA 2Y5GL 5JB8E 2WG3C 1XKAL 1FAXL 1F7MA 1KLIL 1WHFA 2WFTA 1UZKA 1F7EA 3N8ZA 3TK5B 4RS0A 1EMOA 5F19A 1UZQA 2KV4A 1G1TA 1EPJA 2WPLE 4ZXXL 1COUA 2J95B 1KLJL 2TGFA 1UZJA 1URKA 3P5BL 4C16A 1IQHL 2NPRA 1HRFA 2VWNL 1O5DL 5CKMA 3N8YB 3KQEL 3POYA 1FSBA 3GISX 1UZPA 2EI7B 3ZYJB 4Y71B 4X8VL 1IGXA 4BTTA 2XBYL 2GD4A 3ELAL 1MOXC 2XBVL 1G1QA 2W2ME 3KRKA 1Q4GA 1G1RA 1C5MF 2P95L 4XLWA 1LMJA 1FJSL 1HREA 3FBYA 1V3XB 2W3KB 2XC5L 1EQHA 1EPHA 1RFNB 4X8TL 3U73A 2UWPB 2P3FN 1LQDA 3LC3B 2PUQL 2D1JB 2YGQA 2VVUL 2Y7XB 4ISIL 2P16L 4RRYA 1F0RB 1PGEA 2AYLA 4Y79B 1A3PA 1GK5A 2UWLB 1NZIA 1W7XL 1L5GB 3RR3A 2P94L 2WPKE 1Z6CA 4ZH8B 1NT0A 2W2NE 3GCXE 1ADXA 1N7DA 1YUKB 2FLBL 2WG4B 4E1GA 1M1XB 2P93L 2FZZL 1N1IA 3U7UG 2BOUA 5I46L 2I9AA 1G2MB 2BOKL 3M37L 1IOEL 4RRXA 3HPTA 2J38B 2XC4L 1TLEA 1YO8A 1EAIC 4BDXA 1OB1C 1DDXA 2XBXL 6COXA 1IQLL 4D90A 2FLGA 5COXA 3TBDA 2WPIE 1G2LB 4JZDL 2BMGA 2Y5HL 2BOHA 4RUTA 4YZUB 1KLOA 4O1ZA 1XKBA 4ZHAB 2VJ3A 3TZIA 4O02B 3LIWB 2MGRA 2Q1JB 1CQEA 1QFKL 1NFUB 3BT2A 3ASIA 4COXA 1NFXB 1IVOC 2MGPA 3TH3L 2W2QE 2W3IB 1EBVA 2KB9A 1JL9A 3Q7DA 3CFWA 4BDWA 3F1SB 2W26B 1EMNA 4Z0LA 2WPME 1AUTL 4M11A 1EPIA 2FD6A 2K2TA 3N8XA 1P9JA 3CA7A 3CENL 2VVVL 1HZ8A 1ATAA 1PTHA 3V64C 2Y82B 4FM5A 3S6XA 5L30L 3BPSE 3LN1A 1IQML 1MQ5L 1DIYA 1CCFA 1PFXL 2Y81B 4BXWA 1ATDA 1YUFA 3QH0A 1LMMA 2YGPA 4PH9A 2I9BA 1NPEB 3N8WA 5L2YL 5JBCE 2W2OE 4JZFL 1IJQA 1PXXA 5CISA 1FFMA 1HAFA 1EQGA 1CCVA 3SW2A 3ZYGA 4YT7L 4JYVL 2BQ7A 2P26A 4ZXYL 3FFGL 2BQ6A 3HO5A 1X7AL 2ADXA 5JBAE 1BF9A 3KQBL 4MMXB 2CJIB 1ZAQA 1NFYB 3F6UL 3H5CB 3SOBB 4LMFA 1HT8A 4BTIA 1HT5A 1IQGL 2M74A 2B7DL 1K36A 3HS7A 2PR3B 2BO2A 4D0FA 5E8DA 2UWOB 4CSYA 1HAEA 2RNLA 2J94B 2KL7A 3KQCL 3V65B 2OYEP 1WHEA 2BOXA 3LTGD 1ATEA 2H9EC 3N8WB 1J9CL 1DX5I 2W2PE 3MDLA 4ISHL 4Y7AB 1IGZA 2YGOA 2H9EL 3LTFB 2KNIA 4Z0KB 4RRWA 1JBUL 2DDUA 2RA0L 1CEJA 2WFXB 3OLUA 1EZQB 4M10A 4A94C 5JVYA 4Y6DB 4OTJA 3HS6A 1APOA 3M36L 3LN0A 3QMOA 3R05A 1PRHA 1TPGA 4NA9L 1U67A 3HO3A 5JW1A 2P3TA 3LAQA 5JB9E 2Y5FL 2WYJB 1HCGB 4X8SL 2VWLL 3N8YA 4MMYB 1I0UA 4X8UL 2XC0L 2JKHL 4CUFA 1IOXA 4YT6L 4BTUA 2WYGB 1CX2A 4JZEL 2P3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZAE B;  2EI6 B;  2MHP A;  1IQF L;  3NTB A;  4XL1 A;  1LPZ A;  1L3Y A;  3SOV A;  2J34 B;  1KIG L;  3LC5 B;  1DQB A;  5K0H B;  5IKT A;  4JYU L;  2FLR L;  5KN5 C;  1FAK L;  1NQL B;  3KK6 A;  2J2U B;  5FDQ A;  1CVU A;  4Y7B B;  1YGC L;  3K9X A;  3C9A C;  4CUD A;  1IQE L;  1ATB A;  5JVZ A;  5IKV A;  5IKR A;  2J4I B;  2K2S B;  1EPG A;  5IKQ A;  3KQD L;  4OTY A;  4RRZ A;  4TGF A;  1FF7 A;  4Y76 B;  4NGA L;  2VH6 B;  3TK6 B;  3PGH A;  5KIR A;  1XDT R;  2Y38 A;  2P3F L;  5EGM B;  4BXS A;  2RHP A;  3NJP C;  2VVC K;  3SOQ A;  1P0S L;  3NT1 A;  4LOR A;  5JBB E;  5CKQ A;  1LPK A;  3DEM A;  1MQ6 L;  1U8C B;  4AQT A;  1APQ A;  1W8B L;  1XFE A;  4NG9 L;  3QCW A;  2EI8 B;  1K37 A;  2VH0 B;  2OYU P;  2PHB B;  2XBW L;  2WPJ E;  2BQW A;  1B9W A;  2VWO L;  1IQJ L;  2W86 A;  1Z6E L;  4Z6A L;  4G1M B;  3HO4 A;  3ENS A;  4A7I A;  3CS7 L;  3HS5 A;  1TOZ A;  1SZB A;  1IP0 A;  3GCW E;  4MMZ B;  1IQK L;  3BT1 A;  4XBM A;  3TGF A;  1HX2 A;  2VWM K;  3MQE A;  3ZYI B;  1IQN L;  2BZ6 L;  3OLT A;  5L2Z L;  1FE2 A;  2WPH E;  2Y7Z B;  3NTG A;  2Y80 B;  1F0S B;  1YUG A;  3IIT B;  3N8V A;  1IQI L;  1CVW L;  4CUE A;  2F9B L;  3Q3K B;  4D0E A;  5F1A A;  1WU1 B;  2G00 L;  3KL6 B;  3IJE B;  1NFW B;  3EGF A;  3FCS B;  3KCG L;  1DVA L;  1JV2 B;  1G1S A;  1EGF A;  1LPG A;  1KSN B;  2P28 B;  1HJ7 A;  5CKN A;  2Y5G L;  5JB8 E;  2WG3 C;  1XKA L;  1FAX L;  1F7M A;  1KLI L;  1WHF A;  2WFT A;  1UZK A;  1F7E A;  3N8Z A;  3TK5 B;  4RS0 A;  1EMO A;  5F19 A;  1UZQ A;  2KV4 A;  1G1T A;  1EPJ A;  2WPL E;  4ZXX L;  1COU A;  2J95 B;  1KLJ L;  2TGF A;  1UZJ A;  1URK A;  3P5B L;  4C16 A;  1IQH L;  2NPR A;  1HRF A;  2VWN L;  1O5D L;  5CKM A;  3N8Y B;  3KQE L;  3POY A;  1FSB A;  3GIS X;  1UZP A;  2EI7 B;  3ZYJ B;  4Y71 B;  4X8V L;  1IGX A;  4BTT A;  2XBY L;  2GD4 A;  3ELA L;  1MOX C;  2XBV L;  1G1Q A;  2W2M E;  3KRK A;  1Q4G A;  1G1R A;  1C5M F;  2P95 L;  4XLW A;  1LMJ A;  1FJS L;  1HRE A;  3FBY A;  1V3X B;  2W3K B;  2XC5 L;  1EQH A;  1EPH A;  1RFN B;  4X8T L;  3U73 A;  2UWP B;  2P3F N;  1LQD A;  3LC3 B;  2PUQ L;  2D1J B;  2VVU L;  2Y7X B;  4ISI L;  2P16 L;  4RRY A;  1F0R B;  1PGE A;  2AYL A;  4Y79 B;  1A3P A;  1GK5 A;  2UWL B;  1NZI A;  1W7X L;  1L5G B;  3RR3 A;  2P94 L;  2WPK E;  1Z6C A;  4ZH8 B;  1NT0 A;  2W2N E;  3GCX E;  1ADX A;  1N7D A;  1YUK B;  2FLB L;  2WG4 B;  4E1G A;  1M1X B;  2P93 L;  2FZZ L;  1N1I A;  3U7U G;  2BOU A;  5I46 L;  2I9A A;  1G2M B;  2BOK L;  3M37 L;  1IOE L;  4RRX A;  3HPT A;  2J38 B;  2XC4 L;  1TLE A;  1YO8 A;  1EAI C;  4BDX A;  1OB1 C;  1DDX A;  2XBX L;  6COX A;  1IQL L;  4D90 A;  2FLG A;  5COX A;  3TBD A;  2WPI E;  1G2L B;  4JZD L;  2BMG A;  2Y5H L;  2BOH A;  4RUT A;  4YZU B;  1KLO A;  4O1Z A;  1XKB A;  4ZHA B;  2VJ3 A;  3TZI A;  4O02 B;  3LIW B;  2MGR A;  2Q1J B;  1CQE A;  1QFK L;  1NFU B;  3BT2 A;  3ASI A;  4COX A;  1NFX B;  1IVO C;  2MGP A;  3TH3 L;  2W2Q E;  2W3I B;  1EBV A;  2KB9 A;  1JL9 A;  3Q7D A;  3CFW A;  4BDW A;  3F1S B;  2W26 B;  1EMN A;  4Z0L A;  2WPM E;  1AUT L;  4M11 A;  1EPI A;  2FD6 A;  2K2T A;  3N8X A;  1P9J A;  3CA7 A;  3CEN L;  2VVV L;  1HZ8 A;  1ATA A;  1PTH A;  3V64 C;  2Y82 B;  4FM5 A;  5L30 L;  3BPS E;  3LN1 A;  1IQM L;  1MQ5 L;  1DIY A;  1CCF A;  1PFX L;  2Y81 B;  4BXW A;  1ATD A;  1YUF A;  3QH0 A;  2YGP A;  4PH9 A;  2I9B A;  1NPE B;  3N8W A;  5L2Y L;  5JBC E;  2W2O E;  4JZF L;  1IJQ A;  1PXX A;  5CIS A;  1FFM A;  1HAF A;  1EQG A;  1CCV A;  3SW2 A;  3ZYG A;  4YT7 L;  4JYV L;  2BQ7 A;  2P26 A;  4ZXY L;  3FFG L;  2BQ6 A;  3HO5 A;  1X7A L;  2ADX A;  5JBA E;  1BF9 A;  3KQB L;  4MMX B;  2CJI B;  1ZAQ A;  1NFY B;  3F6U L;  3H5C B;  3SOB B;  4LMF A;  1HT8 A;  4BTI A;  1HT5 A;  1IQG L;  2M74 A;  2B7D L;  1K36 A;  3HS7 A;  2PR3 B;  2BO2 A;  4D0F A;  5E8D A;  2UWO B;  4CSY A;  1HAE A;  2RNL A;  2J94 B;  2KL7 A;  3KQC L;  3V65 B;  2OYE P;  1WHE A;  2BOX A;  3LTG D;  1ATE A;  3N8W B;  1J9C L;  1DX5 I;  2W2P E;  3MDL A;  4ISH L;  4Y7A B;  1IGZ A;  2YGO A;  2H9E L;  3LTF B;  4Z0K B;  4RRW A;  1JBU L;  2DDU A;  2RA0 L;  1CEJ A;  2WFX B;  3OLU A;  1EZQ B;  4M10 A;  5JVY A;  4Y6D B;  4OTJ A;  3HS6 A;  1APO A;  3M36 L;  3LN0 A;  3QMO A;  3R05 A;  1PRH A;  1TPG A;  4NA9 L;  1U67 A;  3HO3 A;  5JW1 A;  2P3T A;  3LAQ A;  5JB9 E;  2Y5F L;  2WYJ B;  1HCG B;  4X8S L;  2VWL L;  3N8Y A;  4MMY B;  1I0U A;  4X8U L;  2XC0 L;  2JKH L;  4CUF A;  1IOX A;  4YT6 L;  4BTU A;  2WYG B;  1CX2 A;  4JZE L;  2P3U A; 
#chains in the Genus database with same CATH topology
 1QIU A;  4ZAE B;  2EI6 B;  2MHP A;  1IQF L;  3NTB A;  4XL1 A;  1LPZ A;  1L3Y A;  3SOV A;  2J34 B;  1KIG L;  3LC5 B;  1DQB A;  5K0H B;  2HOX A;  5IKT A;  4JYU L;  2FLR L;  4GU4 A;  5KN5 C;  1FAK L;  1NQL B;  3KK6 A;  2J2U B;  5FDQ A;  1CVU A;  4Y7B B;  1YGC L;  3K9X A;  3C9A C;  4CUD A;  1IQE L;  1ATB A;  5JVZ A;  5IKV A;  5IKR A;  2J4I B;  2K2S B;  1EPG A;  5IKQ A;  3KQD L;  4OTY A;  4RRZ A;  4TGF A;  1FF7 A;  4Y76 B;  4NGA L;  2VH6 B;  3TK6 B;  3PGH A;  5KIR A;  1XDT R;  2Y38 A;  2P3F L;  5EGM B;  4BXS A;  2RHP A;  3NJP C;  2VVC K;  3SOQ A;  1P0S L;  3NT1 A;  4LOR A;  5JBB E;  5CKQ A;  1LPK A;  3DEM A;  1MQ6 L;  1U8C B;  4AQT A;  1APQ A;  1W8B L;  1XFE A;  4NG9 L;  3QCW A;  2EI8 B;  1K37 A;  2VH0 B;  2OYU P;  2PHB B;  2XBW L;  2WPJ E;  2BQW A;  1B9W A;  2VWO L;  1IQJ L;  2W86 A;  2WZP P;  1Z6E L;  4Z6A L;  4G1M B;  3HO4 A;  3ENS A;  4A7I A;  3CS7 L;  3HS5 A;  1TOZ A;  1SZB A;  1IP0 A;  3GCW E;  4MMZ B;  1IQK L;  3BT1 A;  4XBM A;  3TGF A;  1HX2 A;  2VWM K;  3MQE A;  3ZYI B;  1IQN L;  2BT7 A;  2BZ6 L;  3OLT A;  5L2Z L;  1FE2 A;  2WPH E;  2BT8 A;  2Y7Z B;  2Y80 B;  3NTG A;  1F0S B;  1YUG A;  3IIT B;  3N8V A;  1IQI L;  1CVW L;  4CUE A;  2F9B L;  3Q3K B;  4D0E A;  5F1A A;  1WU1 B;  2G00 L;  3KL6 B;  3IJE B;  1NFW B;  3EGF A;  2BSF A;  3FCS B;  3KCG L;  1DVA L;  1JV2 B;  1G1S A;  1EGF A;  1LPG A;  1KSN B;  2P28 B;  1HJ7 A;  2HOR A;  5CKN A;  2Y5G L;  5JB8 E;  2WG3 C;  1XKA L;  1FAX L;  1F7M A;  1LK9 A;  1KLI L;  1WHF A;  2WFT A;  1UZK A;  1F7E A;  3N8Z A;  3TK5 B;  4RS0 A;  1EMO A;  5F19 A;  1UZQ A;  2KV4 A;  1G1T A;  1EPJ A;  2WPL E;  4ZXX L;  1COU A;  2J95 B;  1KLJ L;  2TGF A;  1UZJ A;  1URK A;  3P5B L;  4C16 A;  1IQH L;  2NPR A;  1HRF A;  2VWN L;  1O5D L;  5CKM A;  3N8Y B;  3KQE L;  3POY A;  1FSB A;  3GIS X;  1UZP A;  2EI7 B;  3ZYJ B;  4Y71 B;  4X8V L;  1IGX A;  4BTT A;  2XBY L;  2GD4 A;  3ELA L;  1MOX C;  2XBV L;  1G1Q A;  2W2M E;  3KRK A;  1Q4G A;  1G1R A;  1C5M F;  2P95 L;  4XLW A;  1LMJ A;  1FJS L;  1HRE A;  3FBY A;  1V3X B;  2W3K B;  2XC5 L;  1EQH A;  1EPH A;  1RFN B;  4X8T L;  3U73 A;  2UWP B;  2P3F N;  1LQD A;  3LC3 B;  2PUQ L;  2D1J B;  2YGQ A;  2VVU L;  2Y7X B;  4ISI L;  2P16 L;  4RRY A;  1F0R B;  1PGE A;  2AYL A;  4Y79 B;  1A3P A;  1GK5 A;  1V1H A;  2UWL B;  1NZI A;  1W7X L;  1L5G B;  3RR3 A;  2P94 L;  2WPK E;  1Z6C A;  4ZH8 B;  1NT0 A;  2W2N E;  3GCX E;  1ADX A;  1N7D A;  1YUK B;  2FLB L;  2WG4 B;  4E1G A;  1M1X B;  2P93 L;  2FZZ L;  1N1I A;  3U7U G;  2BOU A;  5I46 L;  2I9A A;  1G2M B;  2BOK L;  3M37 L;  1IOE L;  4RRX A;  3HPT A;  2J38 B;  2XC4 L;  1TLE A;  1YO8 A;  2VRS A;  1EAI C;  4BDX A;  1OB1 C;  1DDX A;  2XBX L;  2JJL A;  6COX A;  1IQL L;  4D90 A;  2FLG A;  5COX A;  3TBD A;  2WPI E;  1G2L B;  4JZD L;  2BMG A;  2Y5H L;  2BOH A;  4RUT A;  4YZU B;  1KLO A;  4O1Z A;  1XKB A;  4ZHA B;  2VJ3 A;  3TZI A;  4O02 B;  3LIW B;  2MGR A;  2Q1J B;  1CQE A;  1QFK L;  1NFU B;  3BT2 A;  3ASI A;  4COX A;  1NFX B;  1IVO C;  2MGP A;  3TH3 L;  2W2Q E;  2W3I B;  1EBV A;  2KB9 A;  1JL9 A;  3Q7D A;  3CFW A;  4BDW A;  3F1S B;  2W26 B;  1EMN A;  4Z0L A;  2WPM E;  1AUT L;  4M11 A;  1EPI A;  2FD6 A;  2K2T A;  3N8X A;  1P9J A;  3CA7 A;  3CEN L;  2VVV L;  1HZ8 A;  1ATA A;  1PTH A;  3V64 C;  2Y82 B;  4FM5 A;  3S6X A;  1V1I A;  5L30 L;  3BPS E;  3LN1 A;  1IQM L;  1MQ5 L;  1DIY A;  1CCF A;  1PFX L;  2Y81 B;  4BXW A;  1ATD A;  1YUF A;  3QH0 A;  1LMM A;  2YGP A;  4PH9 A;  2I9B A;  1NPE B;  3N8W A;  5L2Y L;  5JBC E;  2W2O E;  4JZF L;  1IJQ A;  1PXX A;  5CIS A;  1FFM A;  1HAF A;  1EQG A;  4GU3 A;  1CCV A;  3SW2 A;  3ZYG A;  4YT7 L;  4JYV L;  2BQ7 A;  2P26 A;  4ZXY L;  3FFG L;  2BQ6 A;  3HO5 A;  1X7A L;  2ADX A;  5JBA E;  1BF9 A;  3KQB L;  4MMX B;  2CJI B;  1ZAQ A;  1NFY B;  3F6U L;  3H5C B;  3SOB B;  4LMF A;  1HT8 A;  4BTI A;  1HT5 A;  1IQG L;  2M74 A;  2B7D L;  1K36 A;  3HS7 A;  2PR3 B;  2BO2 A;  4D0F A;  5E8D A;  2UWO B;  4CSY A;  1HAE A;  2RNL A;  2J94 B;  2KL7 A;  3KQC L;  3V65 B;  2OYE P;  1WHE A;  2BOX A;  3LTG D;  1ATE A;  2H9E C;  3N8W B;  1J9C L;  1DX5 I;  2W2P E;  3MDL A;  4ISH L;  4Y7A B;  1IGZ A;  2YGO A;  2H9E L;  3LTF B;  2KNI A;  4Z0K B;  4RRW A;  1JBU L;  2DDU A;  2RA0 L;  1CEJ A;  2WFX B;  3OLU A;  1EZQ B;  4M10 A;  4A94 C;  5JVY A;  4Y6D B;  4OTJ A;  3HS6 A;  1APO A;  1KKE A;  3M36 L;  3LN0 A;  3QMO A;  3R05 A;  1PRH A;  1TPG A;  4NA9 L;  1U67 A;  3HO3 A;  5JW1 A;  2P3T A;  3LAQ A;  5JB9 E;  2Y5F L;  2WYJ B;  1HCG B;  4X8S L;  2VWL L;  3N8Y A;  4MMY B;  1I0U A;  4X8U L;  2XC0 L;  2JKH L;  4CUF A;  1IOX A;  4YT6 L;  4BTU A;  2WYG B;  1CX2 A;  4JZE L;  2P3U A; 
#chains in the Genus database with same CATH homology
 4ZAE B;  2EI6 B;  2MHP A;  1IQF L;  3NTB A;  4XL1 A;  1LPZ A;  1L3Y A;  3SOV A;  2J34 B;  1KIG L;  3LC5 B;  1DQB A;  5K0H B;  5IKT A;  4JYU L;  2FLR L;  5KN5 C;  1FAK L;  1NQL B;  3KK6 A;  2J2U B;  5FDQ A;  1CVU A;  4Y7B B;  1YGC L;  3K9X A;  3C9A C;  4CUD A;  1IQE L;  1ATB A;  5JVZ A;  5IKV A;  5IKR A;  2J4I B;  2K2S B;  1EPG A;  5IKQ A;  3KQD L;  4OTY A;  4RRZ A;  4TGF A;  1FF7 A;  4Y76 B;  4NGA L;  2VH6 B;  3TK6 B;  3PGH A;  5KIR A;  1XDT R;  2Y38 A;  2P3F L;  5EGM B;  4BXS A;  2RHP A;  3NJP C;  2VVC K;  3SOQ A;  1P0S L;  3NT1 A;  4LOR A;  5JBB E;  5CKQ A;  1LPK A;  3DEM A;  1MQ6 L;  1U8C B;  4AQT A;  1APQ A;  1W8B L;  1XFE A;  4NG9 L;  3QCW A;  2EI8 B;  1K37 A;  2VH0 B;  2OYU P;  2PHB B;  2XBW L;  2WPJ E;  2BQW A;  1B9W A;  2VWO L;  1IQJ L;  2W86 A;  2WZP P;  1Z6E L;  4Z6A L;  4G1M B;  3HO4 A;  3ENS A;  4A7I A;  3CS7 L;  3HS5 A;  1TOZ A;  1SZB A;  1IP0 A;  3GCW E;  4MMZ B;  1IQK L;  3BT1 A;  4XBM A;  3TGF A;  1HX2 A;  2VWM K;  3MQE A;  3ZYI B;  1IQN L;  2BZ6 L;  3OLT A;  5L2Z L;  1FE2 A;  2WPH E;  2Y7Z B;  3NTG A;  2Y80 B;  1F0S B;  1YUG A;  3IIT B;  3N8V A;  1IQI L;  1CVW L;  4CUE A;  2F9B L;  3Q3K B;  4D0E A;  5F1A A;  1WU1 B;  2G00 L;  3KL6 B;  3IJE B;  1NFW B;  3EGF A;  3FCS B;  3KCG L;  1DVA L;  1JV2 B;  1G1S A;  1EGF A;  1LPG A;  1KSN B;  2P28 B;  1HJ7 A;  5CKN A;  2Y5G L;  5JB8 E;  2WG3 C;  1XKA L;  1FAX L;  1F7M A;  1KLI L;  1WHF A;  2WFT A;  1UZK A;  1F7E A;  3N8Z A;  3TK5 B;  4RS0 A;  1EMO A;  5F19 A;  1UZQ A;  2KV4 A;  1G1T A;  1EPJ A;  2WPL E;  4ZXX L;  1COU A;  2J95 B;  1KLJ L;  2TGF A;  1UZJ A;  1URK A;  3P5B L;  4C16 A;  1IQH L;  2NPR A;  1HRF A;  2VWN L;  1O5D L;  5CKM A;  3N8Y B;  3KQE L;  3POY A;  1FSB A;  3GIS X;  1UZP A;  2EI7 B;  3ZYJ B;  4Y71 B;  4X8V L;  1IGX A;  4BTT A;  2XBY L;  2GD4 A;  3ELA L;  1MOX C;  2XBV L;  1G1Q A;  2W2M E;  3KRK A;  1Q4G A;  1G1R A;  1C5M F;  2P95 L;  4XLW A;  1LMJ A;  1FJS L;  1HRE A;  3FBY A;  1V3X B;  2W3K B;  2XC5 L;  1EQH A;  1EPH A;  1RFN B;  4X8T L;  3U73 A;  2UWP B;  2P3F N;  1LQD A;  3LC3 B;  2PUQ L;  2D1J B;  2YGQ A;  2VVU L;  2Y7X B;  4ISI L;  2P16 L;  4RRY A;  1F0R B;  1PGE A;  2AYL A;  4Y79 B;  1A3P A;  1GK5 A;  2UWL B;  1NZI A;  1W7X L;  1L5G B;  3RR3 A;  2P94 L;  2WPK E;  1Z6C A;  4ZH8 B;  1NT0 A;  2W2N E;  3GCX E;  1ADX A;  1N7D A;  1YUK B;  2FLB L;  2WG4 B;  4E1G A;  1M1X B;  2P93 L;  2FZZ L;  1N1I A;  3U7U G;  2BOU A;  5I46 L;  2I9A A;  1G2M B;  2BOK L;  3M37 L;  1IOE L;  4RRX A;  3HPT A;  2J38 B;  2XC4 L;  1TLE A;  1YO8 A;  1EAI C;  4BDX A;  1OB1 C;  1DDX A;  2XBX L;  6COX A;  1IQL L;  4D90 A;  2FLG A;  5COX A;  3TBD A;  2WPI E;  1G2L B;  4JZD L;  2BMG A;  2Y5H L;  2BOH A;  4RUT A;  4YZU B;  1KLO A;  4O1Z A;  1XKB A;  4ZHA B;  2VJ3 A;  3TZI A;  4O02 B;  3LIW B;  2MGR A;  2Q1J B;  1CQE A;  1QFK L;  1NFU B;  3BT2 A;  3ASI A;  4COX A;  1NFX B;  1IVO C;  2MGP A;  3TH3 L;  2W2Q E;  2W3I B;  1EBV A;  2KB9 A;  1JL9 A;  3Q7D A;  3CFW A;  4BDW A;  3F1S B;  2W26 B;  1EMN A;  4Z0L A;  2WPM E;  1AUT L;  4M11 A;  1EPI A;  2FD6 A;  2K2T A;  3N8X A;  1P9J A;  3CA7 A;  3CEN L;  2VVV L;  1HZ8 A;  1ATA A;  1PTH A;  3V64 C;  2Y82 B;  4FM5 A;  3S6X A;  5L30 L;  3BPS E;  3LN1 A;  1IQM L;  1MQ5 L;  1DIY A;  1CCF A;  1PFX L;  2Y81 B;  4BXW A;  1ATD A;  1YUF A;  3QH0 A;  1LMM A;  2YGP A;  4PH9 A;  2I9B A;  1NPE B;  3N8W A;  5L2Y L;  5JBC E;  2W2O E;  4JZF L;  1IJQ A;  1PXX A;  5CIS A;  1FFM A;  1HAF A;  1EQG A;  1CCV A;  3SW2 A;  3ZYG A;  4YT7 L;  4JYV L;  2BQ7 A;  2P26 A;  4ZXY L;  3FFG L;  2BQ6 A;  3HO5 A;  1X7A L;  2ADX A;  5JBA E;  1BF9 A;  3KQB L;  4MMX B;  2CJI B;  1ZAQ A;  1NFY B;  3F6U L;  3H5C B;  3SOB B;  4LMF A;  1HT8 A;  4BTI A;  1HT5 A;  1IQG L;  2M74 A;  2B7D L;  1K36 A;  3HS7 A;  2PR3 B;  2BO2 A;  4D0F A;  5E8D A;  2UWO B;  4CSY A;  1HAE A;  2RNL A;  2J94 B;  2KL7 A;  3KQC L;  3V65 B;  2OYE P;  1WHE A;  2BOX A;  3LTG D;  1ATE A;  2H9E C;  3N8W B;  1J9C L;  1DX5 I;  2W2P E;  3MDL A;  4ISH L;  4Y7A B;  1IGZ A;  2YGO A;  2H9E L;  3LTF B;  2KNI A;  4Z0K B;  4RRW A;  1JBU L;  2DDU A;  2RA0 L;  1CEJ A;  2WFX B;  3OLU A;  1EZQ B;  4M10 A;  4A94 C;  5JVY A;  4Y6D B;  4OTJ A;  3HS6 A;  1APO A;  3M36 L;  3LN0 A;  3QMO A;  3R05 A;  1PRH A;  1TPG A;  4NA9 L;  1U67 A;  3HO3 A;  5JW1 A;  2P3T A;  3LAQ A;  5JB9 E;  2Y5F L;  2WYJ B;  1HCG B;  4X8S L;  2VWL L;  3N8Y A;  4MMY B;  1I0U A;  4X8U L;  2XC0 L;  2JKH L;  4CUF A;  1IOX A;  4YT6 L;  4BTU A;  2WYG B;  1CX2 A;  4JZE L;  2P3U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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