2W26B

Factor xa in complex with bay59-7939
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
51
structure length
51
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of the Novel Antithrombotic Agent 5-Chloro-N-({(5S)-2-Oxo-3- [4-(3-Oxomorpholin-4-Yl)Phenyl]-1,3-Oxazolidin-5-Yl}Methyl)Thiophene-2- Carboxamide (Bay 59-7939): An Oral, Direct Factor Xa Inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 11
structure length 51
sequence length 51
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2008-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2w26B00
1EPIA 4RS0A 4O1ZA 4ISHL 2PUQL 1CVUA 3ENSA 4X8SL 2Y80B 2PR3B 1C5MF 1NFUB 2WG4B 1QFKL 1CVWL 2CJIB 1COUA 1G2MB 1M1XB 3N8WA 4BTUA 1MQ6L 1BF9A 1HAFA 4MMXB 1L3YA 3V64C 1WU1B 1UZJA 3IITB 3HS5A 3U7UG 1O5DL 1V3XB 2YGPA 2VVVL 5L2YL 1CCVA 2F9BL 2RHPA 5IKQA 1EBVA 2XC5L 4Y6DB 3ZYJB 1N7DA 2VWNL 4XLWA 5KIRA 5JBBE 2DDUA 2J2UB 4ISIL 2WPKE 1HT5A 4ZXXL 1ATBA 1LMJA 3LN1A 3TK6B 1CEJA 1FJSL 2RNLA 5IKRA 2EI6B 3TGFA 3U73A 4RRWA 1HJ7A 1Z6CA 2W2QE 1J9CL 1PXXA 3N8VA 3KRKA 1IQJL 1IVOC 2MGRA 3KQEL 2GD4A 2P28B 3CENL 4RRYA 4YZUB 2BOHA 1IQKL 5JBAE 1HT8A 3KQCL 1G1QA 4O02B 2WPME 2J34B 1HZ8A 1P0SL 1KSNB 1EMNA 2VH0B 4X8TL 2W2ME 1EMOA 5COXA 1IOXA 3N8YA 1FFMA 4BDXA 3NTBA 1MOXC 2Y82B 1KLOA 3NJPC 3R05A 2J94B 1YGCL 1APQA 2VVUL 3HS7A 3SOQA 4BXSA 1G1TA 2M74A 1W7XL 2BQ7A 3BPSE 2FD6A 5FDQA 4JZDL 3BT2A 5JW1A 5F1AA 2VJ3A 2P3FN 1KLJL 2FLGA 3GISX 2WG3C 2KB9A 2BOKL 1RFNB 2UWOB 3OLTA 4BTIA 2Y5FL 1URKA 1W8BL 3H5CB 4Y7AB 1WHFA 4ZHAB 4XBMA 1SZBA 5L2ZL 2XBYL 1EZQB 5I46L 1Q4GA 1ZAQA 1HAEA 1NPEB 2KV4A 2P3UA 3N8WB 4Z6AL 3SOVA 2VWOL 2UWLB 2BQ6A 1YUGA 2W26B 2BZ6L 3TBDA 3LN0A 1X7AL 3CA7A 2PHBB 2G00L 1DVAL 1EPJA 2WPLE 4OTYA 2XBVL 4NG9L 4RUTA 4XL1A 1NZIA 3MQEA 2Y7XB 4JYVL 1HCGB 2W2PE 4X8VL 1NQLB 3CFWA 4M11A 1UZPA 2D1JB 3POYA 5CKMA 1IQNL 2VH6B 3LTGD 4M10A 4A7IA 2UWPB 2P95L 1G2LB 1PRHA 1U8CB 1DIYA 6COXA 3F1SB 1PGEA 1IQGL 5L30L 2MHPA 4E1GA 2XBWL 4COXA 4G1MB 2AYLA 2BQWA 3HPTA 4D0FA 4C16A 3EGFA 1APOA 1KIGL 2WPHE 3HO5A 1PFXL 1F7EA 4RRXA 3K9XA 4X8UL 2Y5HL 3PGHA 4MMZB 1G1RA 2W3KB 1TOZA 2WFXB 3QMOA 4MMYB 5CKQA 3N8YB 1TPGA 3NT1A 1UZQA 1FE2A 3BT1A 3TH3L 1G1SA 3F6UL 2P94L 1XFEA 1I0UA 4D90A 3LIWB 2VWLL 3SW2A 1HREA 2FLRL 2FLBL 5EGMB 4RRZA 4ZH8B 1LPZA 1JBUL 3GCXE 1U67A 1XKBA 1DQBA 2WFTA 4CUDA 1IGXA 4NGAL 1IOEL 3RR3A 2RA0L 3GCWE 1ADXA 1K37A 1JL9A 2J95B 1NFXB 2BMGA 1A3PA 5CISA 1ATEA 2Y81B 2W3IB 2XBXL 3KL6B 1IQLL 1UZKA 1F7MA 3TZIA 4AQTA 1MQ5L 2W2OE 2OYEP 1IQEL 4PH9A 1WHEA 3KCGL 4BXWA 2J38B 3N8XA 2BO2A 2Y7ZB 4Y71B 1ATAA 2P16L 3FCSB 3SOBB 4JYUL 2WYJB 3C9AC 1HX2A 5E8DA 4Y7BB 2Y5GL 2NPRA 3ASIA 2XC0L 4JZFL 3KQBL 2VVCK 2BOXA 1CX2A 1YUFA 3IJEB 3ELAL 3M37L 5K0HB 1AUTL 3OLUA 4BTTA 1EAIC 3ZYIB 2J4IB 1IGZA 2B7DL 1KLIL 1GK5A 3V65B 4BDWA 2BOUA 5IKTA 3Q7DA 1F0SB 1Z6EL 3CS7L 1IQML 2FZZL 2P26A 5IKVA 2MGPA 4Y76B 3HO3A 5F19A 3LC5B 2H9EL 4TGFA 2I9AA 2ADXA 2P93L 3QH0A 3M36L 1LPGA 4YT7L 4D0EA 2K2TA 4Z0KB 1EQHA 4FM5A 2Y38A 5JB8E 1ATDA 2EI8B 1DDXA 1CQEA 3KK6A 1FAKL 4ZXYL 4CSYA 4JZEL 1N1IA 1XKAL 1LQDA 1IJQA 3MDLA 3NTGA 1F0RB 1LPKA 1IP0A 3TK5B 1JV2B 2TGFA 2VWMK 3HO4A 2JKHL 4Z0LA 4CUFA 5JBCE 5KN5C 1YO8A 5JB9E 2P3TA 4LMFA 5JVYA 2YGOA 3QCWA 1IQIL 1NFWB 1XDTR 2WPJE 1EQGA 3Q3KB 1IQHL 1L5GB 1TLEA 1EPGA 2WYGB 3LC3B 1EGFA 1K36A 1HRFA 1B9WA 1NT0A 2XC4L 3DEMA 4Y79B 1YUKB 1IQFL 4CUEA 1OB1C 3FFGL 2W86A 3FBYA 1FSBA 5JVZA 2P3FL 4NA9L 5CKNA 1P9JA 3LTFB 4LORA 1NFYB 2OYUP 3LAQA 2EI7B 3N8ZA 4YT6L 1FF7A 3KQDL 2I9BA 1DX5I 4ZAEB 2KL7A 2Q1JB 1EPHA 1CCFA 2W2NE 3ZYGA 1PTHA 1FAXL 3P5BL 2K2SB 2WPIE 4OTJA 3HS6A
chains in the Genus database with same CATH superfamily
1EPIA 4RS0A 4O1ZA 4ISHL 2PUQL 1CVUA 3ENSA 4X8SL 2Y80B 2PR3B 1C5MF 1NFUB 2WG4B 1QFKL 1CVWL 2CJIB 1COUA 1G2MB 1M1XB 2KNIA 3N8WA 4BTUA 1MQ6L 1BF9A 1HAFA 1V1HA 4MMXB 1L3YA 3V64C 1WU1B 1UZJA 3IITB 3HS5A 3U7UG 1O5DL 1V3XB 2YGPA 2VVVL 5L2YL 1CCVA 2F9BL 2RHPA 5IKQA 1EBVA 2XC5L 4Y6DB 1QIUA 3ZYJB 1N7DA 2VWNL 4XLWA 5KIRA 5JBBE 2DDUA 2J2UB 4ISIL 2WPKE 1HT5A 4ZXXL 1ATBA 1LMJA 3LN1A 3TK6B 1CEJA 1FJSL 2RNLA 5IKRA 2EI6B 3TGFA 3U73A 4RRWA 1HJ7A 1Z6CA 2W2QE 1J9CL 1PXXA 3N8VA 3KRKA 1IQJL 1IVOC 2MGRA 3KQEL 2GD4A 2P28B 3CENL 4RRYA 4YZUB 2BOHA 1IQKL 5JBAE 1HT8A 3KQCL 1G1QA 4O02B 2WPME 2J34B 1HZ8A 1P0SL 2BT8A 1KSNB 1EMNA 2VH0B 4X8TL 2W2ME 1EMOA 5COXA 4GU3A 1IOXA 3N8YA 1FFMA 4BDXA 3NTBA 1MOXC 2Y82B 1KLOA 3NJPC 3R05A 2J94B 1YGCL 2VRSA 1APQA 2VVUL 3HS7A 3SOQA 4BXSA 1G1TA 2M74A 1LK9A 1W7XL 2BQ7A 3BPSE 2FD6A 5FDQA 4JZDL 3BT2A 5JW1A 5F1AA 2VJ3A 2P3FN 1KLJL 2FLGA 3GISX 2WG3C 2KB9A 2BOKL 1RFNB 2UWOB 3OLTA 4BTIA 2Y5FL 1URKA 1W8BL 3H5CB 4Y7AB 1WHFA 4ZHAB 4XBMA 2YGQA 2HOXA 1SZBA 5L2ZL 2XBYL 1EZQB 5I46L 1Q4GA 1ZAQA 1HAEA 1NPEB 2KV4A 2P3UA 3N8WB 4Z6AL 3SOVA 2VWOL 2UWLB 2BQ6A 1YUGA 2W26B 2BZ6L 3TBDA 4A94C 3LN0A 1X7AL 3CA7A 2PHBB 2G00L 1DVAL 1EPJA 2WPLE 4OTYA 2XBVL 4NG9L 4RUTA 4XL1A 1NZIA 3MQEA 2Y7XB 4JYVL 1HCGB 2W2PE 4X8VL 1NQLB 3CFWA 4M11A 1UZPA 2D1JB 3POYA 5CKMA 1IQNL 2VH6B 3LTGD 4M10A 4A7IA 2UWPB 2P95L 1G2LB 1PRHA 1U8CB 1DIYA 6COXA 3F1SB 1PGEA 1IQGL 5L30L 2MHPA 4E1GA 2XBWL 4COXA 4G1MB 2AYLA 2BQWA 3HPTA 4D0FA 4C16A 3EGFA 1APOA 1KIGL 2WPHE 3HO5A 1PFXL 1F7EA 4RRXA 3K9XA 4X8UL 2Y5HL 3PGHA 4MMZB 1G1RA 2W3KB 1TOZA 2WFXB 3QMOA 4MMYB 5CKQA 3N8YB 1TPGA 3NT1A 1UZQA 1FE2A 3BT1A 3TH3L 1G1SA 3F6UL 2P94L 1XFEA 1I0UA 4D90A 3LIWB 2VWLL 3SW2A 1HREA 2FLRL 2FLBL 5EGMB 4RRZA 4GU4A 4ZH8B 1LPZA 1JBUL 3GCXE 1U67A 1XKBA 1DQBA 2WFTA 4CUDA 1IGXA 4NGAL 1IOEL 3RR3A 2RA0L 3GCWE 1ADXA 1K37A 1JL9A 2J95B 1NFXB 2BMGA 1A3PA 5CISA 1KKEA 1ATEA 2Y81B 2W3IB 2XBXL 3KL6B 1IQLL 1UZKA 1F7MA 3TZIA 4AQTA 1MQ5L 2W2OE 2OYEP 1IQEL 4PH9A 1WHEA 3KCGL 2JJLA 4BXWA 2J38B 3N8XA 2BO2A 2Y7ZB 4Y71B 1ATAA 2P16L 3FCSB 3SOBB 4JYUL 2WYJB 3C9AC 1HX2A 2BT7A 5E8DA 4Y7BB 2Y5GL 2NPRA 3ASIA 2XC0L 4JZFL 3KQBL 1LMMA 2VVCK 2BOXA 1CX2A 1YUFA 3IJEB 3ELAL 1V1IA 3M37L 2WZPP 5K0HB 1AUTL 3OLUA 4BTTA 1EAIC 3ZYIB 2J4IB 1IGZA 2B7DL 1KLIL 1GK5A 3V65B 4BDWA 2BOUA 2HORA 5IKTA 3Q7DA 1F0SB 1Z6EL 3CS7L 1IQML 2FZZL 2P26A 5IKVA 2MGPA 4Y76B 3HO3A 5F19A 3LC5B 2H9EL 4TGFA 2I9AA 2ADXA 2P93L 3QH0A 3M36L 1LPGA 4YT7L 4D0EA 2K2TA 4Z0KB 1EQHA 4FM5A 2Y38A 5JB8E 1ATDA 2EI8B 1DDXA 1CQEA 3KK6A 1FAKL 4ZXYL 4CSYA 2BSFA 4JZEL 1N1IA 1XKAL 1LQDA 1IJQA 3MDLA 3NTGA 1F0RB 1LPKA 1IP0A 3TK5B 1JV2B 2TGFA 2VWMK 3HO4A 2JKHL 4Z0LA 4CUFA 5JBCE 5KN5C 1YO8A 5JB9E 2P3TA 4LMFA 5JVYA 2YGOA 3QCWA 1IQIL 1NFWB 1XDTR 2WPJE 1EQGA 3Q3KB 1IQHL 1L5GB 1TLEA 1EPGA 2WYGB 3LC3B 1EGFA 1K36A 1HRFA 1B9WA 1NT0A 2XC4L 3DEMA 2H9EC 4Y79B 1YUKB 1IQFL 4CUEA 1OB1C 3FFGL 2W86A 3FBYA 1FSBA 5JVZA 2P3FL 4NA9L 5CKNA 1P9JA 3LTFB 4LORA 1NFYB 2OYUP 3LAQA 2EI7B 3N8ZA 4YT6L 1FF7A 3KQDL 2I9BA 1DX5I 3S6XA 4ZAEB 2KL7A 2Q1JB 1EPHA 1CCFA 2W2NE 3ZYGA 1PTHA 1FAXL 3P5BL 2K2SB 2WPIE 4OTJA 3HS6A
chains in the Genus database with same CATH topology
1EPIA 4RS0A 4O1ZA 4ISHL 2PUQL 1CVUA 3ENSA 4X8SL 2Y80B 2PR3B 1C5MF 1NFUB 2WG4B 1QFKL 1CVWL 2CJIB 1COUA 1G2MB 1M1XB 2KNIA 3N8WA 4BTUA 1MQ6L 1BF9A 1HAFA 4MMXB 1L3YA 3V64C 1WU1B 1UZJA 3IITB 3HS5A 3U7UG 1O5DL 1V3XB 2YGPA 2VVVL 5L2YL 1CCVA 2F9BL 2RHPA 5IKQA 1EBVA 2XC5L 4Y6DB 3ZYJB 1N7DA 2VWNL 4XLWA 5KIRA 5JBBE 2DDUA 2J2UB 4ISIL 2WPKE 1HT5A 4ZXXL 1ATBA 1LMJA 3LN1A 3TK6B 1CEJA 1FJSL 2RNLA 5IKRA 2EI6B 3TGFA 3U73A 4RRWA 1HJ7A 1Z6CA 2W2QE 1J9CL 1PXXA 3N8VA 3KRKA 1IQJL 1IVOC 2MGRA 3KQEL 2GD4A 2P28B 3CENL 4RRYA 4YZUB 2BOHA 1IQKL 5JBAE 1HT8A 3KQCL 1G1QA 4O02B 2WPME 2J34B 1HZ8A 1P0SL 1KSNB 1EMNA 2VH0B 4X8TL 2W2ME 1EMOA 5COXA 1IOXA 3N8YA 1FFMA 4BDXA 3NTBA 1MOXC 2Y82B 1KLOA 3NJPC 3R05A 2J94B 1YGCL 1APQA 2VVUL 3HS7A 3SOQA 4BXSA 1G1TA 2M74A 1W7XL 2BQ7A 3BPSE 2FD6A 5FDQA 4JZDL 3BT2A 5JW1A 5F1AA 2VJ3A 2P3FN 1KLJL 2FLGA 3GISX 2WG3C 2KB9A 2BOKL 1RFNB 2UWOB 3OLTA 4BTIA 2Y5FL 1URKA 1W8BL 3H5CB 4Y7AB 1WHFA 4ZHAB 4XBMA 2YGQA 1SZBA 5L2ZL 2XBYL 1EZQB 5I46L 1Q4GA 1ZAQA 1HAEA 1NPEB 2KV4A 2P3UA 3N8WB 4Z6AL 3SOVA 2VWOL 2UWLB 2BQ6A 1YUGA 2W26B 2BZ6L 3TBDA 4A94C 3LN0A 1X7AL 3CA7A 2PHBB 2G00L 1DVAL 1EPJA 2WPLE 4OTYA 2XBVL 4NG9L 4RUTA 4XL1A 1NZIA 3MQEA 2Y7XB 4JYVL 1HCGB 2W2PE 4X8VL 1NQLB 3CFWA 4M11A 1UZPA 2D1JB 3POYA 5CKMA 1IQNL 2VH6B 3LTGD 4M10A 4A7IA 2UWPB 2P95L 1G2LB 1PRHA 1U8CB 1DIYA 6COXA 3F1SB 1PGEA 1IQGL 5L30L 2MHPA 4E1GA 2XBWL 4COXA 4G1MB 2AYLA 2BQWA 3HPTA 4D0FA 4C16A 3EGFA 1APOA 1KIGL 2WPHE 3HO5A 1PFXL 1F7EA 4RRXA 3K9XA 4X8UL 2Y5HL 3PGHA 4MMZB 1G1RA 2W3KB 1TOZA 2WFXB 3QMOA 4MMYB 5CKQA 3N8YB 1TPGA 3NT1A 1UZQA 1FE2A 3BT1A 3TH3L 1G1SA 3F6UL 2P94L 1XFEA 1I0UA 4D90A 3LIWB 2VWLL 3SW2A 1HREA 2FLRL 2FLBL 5EGMB 4RRZA 4ZH8B 1LPZA 1JBUL 3GCXE 1U67A 1XKBA 1DQBA 2WFTA 4CUDA 1IGXA 4NGAL 1IOEL 3RR3A 2RA0L 3GCWE 1ADXA 1K37A 1JL9A 2J95B 1NFXB 2BMGA 1A3PA 5CISA 1ATEA 2Y81B 2W3IB 2XBXL 3KL6B 1IQLL 1UZKA 1F7MA 3TZIA 4AQTA 1MQ5L 2W2OE 2OYEP 1IQEL 4PH9A 1WHEA 3KCGL 4BXWA 2J38B 3N8XA 2BO2A 2Y7ZB 4Y71B 1ATAA 2P16L 3FCSB 3SOBB 4JYUL 2WYJB 3C9AC 1HX2A 5E8DA 4Y7BB 2Y5GL 2NPRA 3ASIA 2XC0L 4JZFL 3KQBL 1LMMA 2VVCK 2BOXA 1CX2A 1YUFA 3IJEB 3ELAL 3M37L 2WZPP 5K0HB 1AUTL 3OLUA 4BTTA 1EAIC 3ZYIB 2J4IB 1IGZA 2B7DL 1KLIL 1GK5A 3V65B 4BDWA 2BOUA 5IKTA 3Q7DA 1F0SB 1Z6EL 3CS7L 1IQML 2FZZL 2P26A 5IKVA 2MGPA 4Y76B 3HO3A 5F19A 3LC5B 2H9EL 4TGFA 2I9AA 2ADXA 2P93L 3QH0A 3M36L 1LPGA 4YT7L 4D0EA 2K2TA 4Z0KB 1EQHA 4FM5A 2Y38A 5JB8E 1ATDA 2EI8B 1DDXA 1CQEA 3KK6A 1FAKL 4ZXYL 4CSYA 4JZEL 1N1IA 1XKAL 1LQDA 1IJQA 3MDLA 3NTGA 1F0RB 1LPKA 1IP0A 3TK5B 1JV2B 2TGFA 2VWMK 3HO4A 2JKHL 4Z0LA 4CUFA 5JBCE 5KN5C 1YO8A 5JB9E 2P3TA 4LMFA 5JVYA 2YGOA 3QCWA 1IQIL 1NFWB 1XDTR 2WPJE 1EQGA 3Q3KB 1IQHL 1L5GB 1TLEA 1EPGA 2WYGB 3LC3B 1EGFA 1K36A 1HRFA 1B9WA 1NT0A 2XC4L 3DEMA 2H9EC 4Y79B 1YUKB 1IQFL 4CUEA 1OB1C 3FFGL 2W86A 3FBYA 1FSBA 5JVZA 2P3FL 4NA9L 5CKNA 1P9JA 3LTFB 4LORA 1NFYB 2OYUP 3LAQA 2EI7B 3N8ZA 4YT6L 1FF7A 3KQDL 2I9BA 1DX5I 3S6XA 4ZAEB 2KL7A 2Q1JB 1EPHA 1CCFA 2W2NE 3ZYGA 1PTHA 1FAXL 3P5BL 2K2SB 2WPIE 4OTJA 3HS6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EPI A;  4RS0 A;  4O1Z A;  4ISH L;  2PUQ L;  1CVU A;  3ENS A;  4X8S L;  2Y80 B;  2PR3 B;  1C5M F;  1NFU B;  2WG4 B;  1QFK L;  1CVW L;  2CJI B;  1COU A;  1G2M B;  1M1X B;  3N8W A;  4BTU A;  1MQ6 L;  1BF9 A;  1HAF A;  4MMX B;  1L3Y A;  3V64 C;  1WU1 B;  1UZJ A;  3IIT B;  3HS5 A;  3U7U G;  1O5D L;  1V3X B;  2YGP A;  2VVV L;  5L2Y L;  1CCV A;  2F9B L;  2RHP A;  5IKQ A;  1EBV A;  2XC5 L;  4Y6D B;  3ZYJ B;  1N7D A;  2VWN L;  4XLW A;  5KIR A;  5JBB E;  2DDU A;  2J2U B;  4ISI L;  2WPK E;  1HT5 A;  4ZXX L;  1ATB A;  1LMJ A;  3LN1 A;  3TK6 B;  1CEJ A;  1FJS L;  2RNL A;  5IKR A;  2EI6 B;  3TGF A;  3U73 A;  4RRW A;  1HJ7 A;  1Z6C A;  2W2Q E;  1J9C L;  1PXX A;  3N8V A;  3KRK A;  1IQJ L;  1IVO C;  2MGR A;  3KQE L;  2GD4 A;  2P28 B;  3CEN L;  4RRY A;  4YZU B;  2BOH A;  1IQK L;  5JBA E;  1HT8 A;  3KQC L;  1G1Q A;  4O02 B;  2WPM E;  2J34 B;  1HZ8 A;  1P0S L;  1KSN B;  1EMN A;  2VH0 B;  4X8T L;  2W2M E;  1EMO A;  5COX A;  1IOX A;  3N8Y A;  1FFM A;  4BDX A;  3NTB A;  1MOX C;  2Y82 B;  1KLO A;  3NJP C;  3R05 A;  2J94 B;  1YGC L;  1APQ A;  2VVU L;  3HS7 A;  3SOQ A;  4BXS A;  1G1T A;  2M74 A;  1W7X L;  2BQ7 A;  3BPS E;  2FD6 A;  5FDQ A;  4JZD L;  3BT2 A;  5JW1 A;  5F1A A;  2VJ3 A;  2P3F N;  1KLJ L;  2FLG A;  3GIS X;  2WG3 C;  2KB9 A;  2BOK L;  1RFN B;  2UWO B;  3OLT A;  4BTI A;  2Y5F L;  1URK A;  1W8B L;  3H5C B;  4Y7A B;  1WHF A;  4ZHA B;  4XBM A;  1SZB A;  5L2Z L;  2XBY L;  1EZQ B;  5I46 L;  1Q4G A;  1ZAQ A;  1HAE A;  1NPE B;  2KV4 A;  2P3U A;  3N8W B;  4Z6A L;  3SOV A;  2VWO L;  2UWL B;  2BQ6 A;  1YUG A;  2W26 B;  2BZ6 L;  3TBD A;  3LN0 A;  1X7A L;  3CA7 A;  2PHB B;  2G00 L;  1DVA L;  1EPJ A;  2WPL E;  4OTY A;  2XBV L;  4NG9 L;  4RUT A;  4XL1 A;  1NZI A;  3MQE A;  2Y7X B;  4JYV L;  1HCG B;  2W2P E;  4X8V L;  1NQL B;  3CFW A;  4M11 A;  1UZP A;  2D1J B;  3POY A;  5CKM A;  1IQN L;  2VH6 B;  3LTG D;  4M10 A;  4A7I A;  2UWP B;  2P95 L;  1G2L B;  1PRH A;  1U8C B;  1DIY A;  6COX A;  3F1S B;  1PGE A;  1IQG L;  5L30 L;  2MHP A;  4E1G A;  2XBW L;  4COX A;  4G1M B;  2AYL A;  2BQW A;  3HPT A;  4D0F A;  4C16 A;  3EGF A;  1APO A;  1KIG L;  2WPH E;  3HO5 A;  1PFX L;  1F7E A;  4RRX A;  3K9X A;  4X8U L;  2Y5H L;  3PGH A;  4MMZ B;  1G1R A;  2W3K B;  1TOZ A;  2WFX B;  3QMO A;  4MMY B;  5CKQ A;  3N8Y B;  1TPG A;  3NT1 A;  1UZQ A;  1FE2 A;  3BT1 A;  3TH3 L;  1G1S A;  3F6U L;  2P94 L;  1XFE A;  1I0U A;  4D90 A;  3LIW B;  2VWL L;  3SW2 A;  1HRE A;  2FLR L;  2FLB L;  5EGM B;  4RRZ A;  4ZH8 B;  1LPZ A;  1JBU L;  3GCX E;  1U67 A;  1XKB A;  1DQB A;  2WFT A;  4CUD A;  1IGX A;  4NGA L;  1IOE L;  3RR3 A;  2RA0 L;  3GCW E;  1ADX A;  1K37 A;  1JL9 A;  2J95 B;  1NFX B;  2BMG A;  1A3P A;  5CIS A;  1ATE A;  2Y81 B;  2W3I B;  2XBX L;  3KL6 B;  1IQL L;  1UZK A;  1F7M A;  3TZI A;  4AQT A;  1MQ5 L;  2W2O E;  2OYE P;  1IQE L;  4PH9 A;  1WHE A;  3KCG L;  4BXW A;  2J38 B;  3N8X A;  2BO2 A;  2Y7Z B;  4Y71 B;  1ATA A;  2P16 L;  3FCS B;  3SOB B;  4JYU L;  2WYJ B;  3C9A C;  1HX2 A;  5E8D A;  4Y7B B;  2Y5G L;  2NPR A;  3ASI A;  2XC0 L;  4JZF L;  3KQB L;  2VVC K;  2BOX A;  1CX2 A;  1YUF A;  3IJE B;  3ELA L;  3M37 L;  5K0H B;  1AUT L;  3OLU A;  4BTT A;  1EAI C;  3ZYI B;  2J4I B;  1IGZ A;  2B7D L;  1KLI L;  1GK5 A;  3V65 B;  4BDW A;  2BOU A;  5IKT A;  3Q7D A;  1F0S B;  1Z6E L;  3CS7 L;  1IQM L;  2FZZ L;  2P26 A;  5IKV A;  2MGP A;  4Y76 B;  3HO3 A;  5F19 A;  3LC5 B;  2H9E L;  4TGF A;  2I9A A;  2ADX A;  2P93 L;  3QH0 A;  3M36 L;  1LPG A;  4YT7 L;  4D0E A;  2K2T A;  4Z0K B;  1EQH A;  4FM5 A;  2Y38 A;  5JB8 E;  1ATD A;  2EI8 B;  1DDX A;  1CQE A;  3KK6 A;  1FAK L;  4ZXY L;  4CSY A;  4JZE L;  1N1I A;  1XKA L;  1LQD A;  1IJQ A;  3MDL A;  3NTG A;  1F0R B;  1LPK A;  1IP0 A;  3TK5 B;  1JV2 B;  2TGF A;  2VWM K;  3HO4 A;  2JKH L;  4Z0L A;  4CUF A;  5JBC E;  5KN5 C;  1YO8 A;  5JB9 E;  2P3T A;  4LMF A;  5JVY A;  2YGO A;  3QCW A;  1IQI L;  1NFW B;  1XDT R;  2WPJ E;  1EQG A;  3Q3K B;  1IQH L;  1L5G B;  1TLE A;  1EPG A;  2WYG B;  3LC3 B;  1EGF A;  1K36 A;  1HRF A;  1B9W A;  1NT0 A;  2XC4 L;  3DEM A;  4Y79 B;  1YUK B;  1IQF L;  4CUE A;  1OB1 C;  3FFG L;  2W86 A;  3FBY A;  1FSB A;  5JVZ A;  2P3F L;  4NA9 L;  5CKN A;  1P9J A;  3LTF B;  4LOR A;  1NFY B;  2OYU P;  3LAQ A;  2EI7 B;  3N8Z A;  4YT6 L;  1FF7 A;  3KQD L;  2I9B A;  1DX5 I;  4ZAE B;  2KL7 A;  2Q1J B;  1EPH A;  1CCF A;  2W2N E;  3ZYG A;  1PTH A;  1FAX L;  3P5B L;  2K2S B;  2WPI E;  4OTJ A;  3HS6 A; 
#chains in the Genus database with same CATH topology
 1EPI A;  4RS0 A;  4O1Z A;  4ISH L;  2PUQ L;  1CVU A;  3ENS A;  4X8S L;  2Y80 B;  2PR3 B;  1C5M F;  1NFU B;  2WG4 B;  1QFK L;  1CVW L;  2CJI B;  1COU A;  1G2M B;  1M1X B;  2KNI A;  3N8W A;  4BTU A;  1MQ6 L;  1BF9 A;  1HAF A;  1V1H A;  4MMX B;  1L3Y A;  3V64 C;  1WU1 B;  1UZJ A;  3IIT B;  3HS5 A;  3U7U G;  1O5D L;  1V3X B;  2YGP A;  2VVV L;  5L2Y L;  1CCV A;  2F9B L;  2RHP A;  5IKQ A;  1EBV A;  2XC5 L;  4Y6D B;  1QIU A;  3ZYJ B;  1N7D A;  2VWN L;  4XLW A;  5KIR A;  5JBB E;  2DDU A;  2J2U B;  4ISI L;  2WPK E;  1HT5 A;  4ZXX L;  1ATB A;  1LMJ A;  3LN1 A;  3TK6 B;  1CEJ A;  1FJS L;  2RNL A;  5IKR A;  2EI6 B;  3TGF A;  3U73 A;  4RRW A;  1HJ7 A;  1Z6C A;  2W2Q E;  1J9C L;  1PXX A;  3N8V A;  3KRK A;  1IQJ L;  1IVO C;  2MGR A;  3KQE L;  2GD4 A;  2P28 B;  3CEN L;  4RRY A;  4YZU B;  2BOH A;  1IQK L;  5JBA E;  1HT8 A;  3KQC L;  1G1Q A;  4O02 B;  2WPM E;  2J34 B;  1HZ8 A;  1P0S L;  2BT8 A;  1KSN B;  1EMN A;  2VH0 B;  4X8T L;  2W2M E;  1EMO A;  5COX A;  4GU3 A;  1IOX A;  3N8Y A;  1FFM A;  4BDX A;  3NTB A;  1MOX C;  2Y82 B;  1KLO A;  3NJP C;  3R05 A;  2J94 B;  1YGC L;  2VRS A;  1APQ A;  2VVU L;  3HS7 A;  3SOQ A;  4BXS A;  1G1T A;  2M74 A;  1LK9 A;  1W7X L;  2BQ7 A;  3BPS E;  2FD6 A;  5FDQ A;  4JZD L;  3BT2 A;  5JW1 A;  5F1A A;  2VJ3 A;  2P3F N;  1KLJ L;  2FLG A;  3GIS X;  2WG3 C;  2KB9 A;  2BOK L;  1RFN B;  2UWO B;  3OLT A;  4BTI A;  2Y5F L;  1URK A;  1W8B L;  3H5C B;  4Y7A B;  1WHF A;  4ZHA B;  4XBM A;  2YGQ A;  2HOX A;  1SZB A;  5L2Z L;  2XBY L;  1EZQ B;  5I46 L;  1Q4G A;  1ZAQ A;  1HAE A;  1NPE B;  2KV4 A;  2P3U A;  3N8W B;  4Z6A L;  3SOV A;  2VWO L;  2UWL B;  2BQ6 A;  1YUG A;  2W26 B;  2BZ6 L;  3TBD A;  4A94 C;  3LN0 A;  1X7A L;  3CA7 A;  2PHB B;  2G00 L;  1DVA L;  1EPJ A;  2WPL E;  4OTY A;  2XBV L;  4NG9 L;  4RUT A;  4XL1 A;  1NZI A;  3MQE A;  2Y7X B;  4JYV L;  1HCG B;  2W2P E;  4X8V L;  1NQL B;  3CFW A;  4M11 A;  1UZP A;  2D1J B;  3POY A;  5CKM A;  1IQN L;  2VH6 B;  3LTG D;  4M10 A;  4A7I A;  2UWP B;  2P95 L;  1G2L B;  1PRH A;  1U8C B;  1DIY A;  6COX A;  3F1S B;  1PGE A;  1IQG L;  5L30 L;  2MHP A;  4E1G A;  2XBW L;  4COX A;  4G1M B;  2AYL A;  2BQW A;  3HPT A;  4D0F A;  4C16 A;  3EGF A;  1APO A;  1KIG L;  2WPH E;  3HO5 A;  1PFX L;  1F7E A;  4RRX A;  3K9X A;  4X8U L;  2Y5H L;  3PGH A;  4MMZ B;  1G1R A;  2W3K B;  1TOZ A;  2WFX B;  3QMO A;  4MMY B;  5CKQ A;  3N8Y B;  1TPG A;  3NT1 A;  1UZQ A;  1FE2 A;  3BT1 A;  3TH3 L;  1G1S A;  3F6U L;  2P94 L;  1XFE A;  1I0U A;  4D90 A;  3LIW B;  2VWL L;  3SW2 A;  1HRE A;  2FLR L;  2FLB L;  5EGM B;  4RRZ A;  4GU4 A;  4ZH8 B;  1LPZ A;  1JBU L;  3GCX E;  1U67 A;  1XKB A;  1DQB A;  2WFT A;  4CUD A;  1IGX A;  4NGA L;  1IOE L;  3RR3 A;  2RA0 L;  3GCW E;  1ADX A;  1K37 A;  1JL9 A;  2J95 B;  1NFX B;  2BMG A;  1A3P A;  5CIS A;  1KKE A;  1ATE A;  2Y81 B;  2W3I B;  2XBX L;  3KL6 B;  1IQL L;  1UZK A;  1F7M A;  3TZI A;  4AQT A;  1MQ5 L;  2W2O E;  2OYE P;  1IQE L;  4PH9 A;  1WHE A;  3KCG L;  2JJL A;  4BXW A;  2J38 B;  3N8X A;  2BO2 A;  2Y7Z B;  4Y71 B;  1ATA A;  2P16 L;  3FCS B;  3SOB B;  4JYU L;  2WYJ B;  3C9A C;  1HX2 A;  2BT7 A;  5E8D A;  4Y7B B;  2Y5G L;  2NPR A;  3ASI A;  2XC0 L;  4JZF L;  3KQB L;  1LMM A;  2VVC K;  2BOX A;  1CX2 A;  1YUF A;  3IJE B;  3ELA L;  1V1I A;  3M37 L;  2WZP P;  5K0H B;  1AUT L;  3OLU A;  4BTT A;  1EAI C;  3ZYI B;  2J4I B;  1IGZ A;  2B7D L;  1KLI L;  1GK5 A;  3V65 B;  4BDW A;  2BOU A;  2HOR A;  5IKT A;  3Q7D A;  1F0S B;  1Z6E L;  3CS7 L;  1IQM L;  2FZZ L;  2P26 A;  5IKV A;  2MGP A;  4Y76 B;  3HO3 A;  5F19 A;  3LC5 B;  2H9E L;  4TGF A;  2I9A A;  2ADX A;  2P93 L;  3QH0 A;  3M36 L;  1LPG A;  4YT7 L;  4D0E A;  2K2T A;  4Z0K B;  1EQH A;  4FM5 A;  2Y38 A;  5JB8 E;  1ATD A;  2EI8 B;  1DDX A;  1CQE A;  3KK6 A;  1FAK L;  4ZXY L;  4CSY A;  2BSF A;  4JZE L;  1N1I A;  1XKA L;  1LQD A;  1IJQ A;  3MDL A;  3NTG A;  1F0R B;  1LPK A;  1IP0 A;  3TK5 B;  1JV2 B;  2TGF A;  2VWM K;  3HO4 A;  2JKH L;  4Z0L A;  4CUF A;  5JBC E;  5KN5 C;  1YO8 A;  5JB9 E;  2P3T A;  4LMF A;  5JVY A;  2YGO A;  3QCW A;  1IQI L;  1NFW B;  1XDT R;  2WPJ E;  1EQG A;  3Q3K B;  1IQH L;  1L5G B;  1TLE A;  1EPG A;  2WYG B;  3LC3 B;  1EGF A;  1K36 A;  1HRF A;  1B9W A;  1NT0 A;  2XC4 L;  3DEM A;  2H9E C;  4Y79 B;  1YUK B;  1IQF L;  4CUE A;  1OB1 C;  3FFG L;  2W86 A;  3FBY A;  1FSB A;  5JVZ A;  2P3F L;  4NA9 L;  5CKN A;  1P9J A;  3LTF B;  4LOR A;  1NFY B;  2OYU P;  3LAQ A;  2EI7 B;  3N8Z A;  4YT6 L;  1FF7 A;  3KQD L;  2I9B A;  1DX5 I;  3S6X A;  4ZAE B;  2KL7 A;  2Q1J B;  1EPH A;  1CCF A;  2W2N E;  3ZYG A;  1PTH A;  1FAX L;  3P5B L;  2K2S B;  2WPI E;  4OTJ A;  3HS6 A; 
#chains in the Genus database with same CATH homology
 1EPI A;  4RS0 A;  4O1Z A;  4ISH L;  2PUQ L;  1CVU A;  3ENS A;  4X8S L;  2Y80 B;  2PR3 B;  1C5M F;  1NFU B;  2WG4 B;  1QFK L;  1CVW L;  2CJI B;  1COU A;  1G2M B;  1M1X B;  2KNI A;  3N8W A;  4BTU A;  1MQ6 L;  1BF9 A;  1HAF A;  4MMX B;  1L3Y A;  3V64 C;  1WU1 B;  1UZJ A;  3IIT B;  3HS5 A;  3U7U G;  1O5D L;  1V3X B;  2YGP A;  2VVV L;  5L2Y L;  1CCV A;  2F9B L;  2RHP A;  5IKQ A;  1EBV A;  2XC5 L;  4Y6D B;  3ZYJ B;  1N7D A;  2VWN L;  4XLW A;  5KIR A;  5JBB E;  2DDU A;  2J2U B;  4ISI L;  2WPK E;  1HT5 A;  4ZXX L;  1ATB A;  1LMJ A;  3LN1 A;  3TK6 B;  1CEJ A;  1FJS L;  2RNL A;  5IKR A;  2EI6 B;  3TGF A;  3U73 A;  4RRW A;  1HJ7 A;  1Z6C A;  2W2Q E;  1J9C L;  1PXX A;  3N8V A;  3KRK A;  1IQJ L;  1IVO C;  2MGR A;  3KQE L;  2GD4 A;  2P28 B;  3CEN L;  4RRY A;  4YZU B;  2BOH A;  1IQK L;  5JBA E;  1HT8 A;  3KQC L;  1G1Q A;  4O02 B;  2WPM E;  2J34 B;  1HZ8 A;  1P0S L;  1KSN B;  1EMN A;  2VH0 B;  4X8T L;  2W2M E;  1EMO A;  5COX A;  1IOX A;  3N8Y A;  1FFM A;  4BDX A;  3NTB A;  1MOX C;  2Y82 B;  1KLO A;  3NJP C;  3R05 A;  2J94 B;  1YGC L;  1APQ A;  2VVU L;  3HS7 A;  3SOQ A;  4BXS A;  1G1T A;  2M74 A;  1W7X L;  2BQ7 A;  3BPS E;  2FD6 A;  5FDQ A;  4JZD L;  3BT2 A;  5JW1 A;  5F1A A;  2VJ3 A;  2P3F N;  1KLJ L;  2FLG A;  3GIS X;  2WG3 C;  2KB9 A;  2BOK L;  1RFN B;  2UWO B;  3OLT A;  4BTI A;  2Y5F L;  1URK A;  1W8B L;  3H5C B;  4Y7A B;  1WHF A;  4ZHA B;  4XBM A;  2YGQ A;  1SZB A;  5L2Z L;  2XBY L;  1EZQ B;  5I46 L;  1Q4G A;  1ZAQ A;  1HAE A;  1NPE B;  2KV4 A;  2P3U A;  3N8W B;  4Z6A L;  3SOV A;  2VWO L;  2UWL B;  2BQ6 A;  1YUG A;  2W26 B;  2BZ6 L;  3TBD A;  4A94 C;  3LN0 A;  1X7A L;  3CA7 A;  2PHB B;  2G00 L;  1DVA L;  1EPJ A;  2WPL E;  4OTY A;  2XBV L;  4NG9 L;  4RUT A;  4XL1 A;  1NZI A;  3MQE A;  2Y7X B;  4JYV L;  1HCG B;  2W2P E;  4X8V L;  1NQL B;  3CFW A;  4M11 A;  1UZP A;  2D1J B;  3POY A;  5CKM A;  1IQN L;  2VH6 B;  3LTG D;  4M10 A;  4A7I A;  2UWP B;  2P95 L;  1G2L B;  1PRH A;  1U8C B;  1DIY A;  6COX A;  3F1S B;  1PGE A;  1IQG L;  5L30 L;  2MHP A;  4E1G A;  2XBW L;  4COX A;  4G1M B;  2AYL A;  2BQW A;  3HPT A;  4D0F A;  4C16 A;  3EGF A;  1APO A;  1KIG L;  2WPH E;  3HO5 A;  1PFX L;  1F7E A;  4RRX A;  3K9X A;  4X8U L;  2Y5H L;  3PGH A;  4MMZ B;  1G1R A;  2W3K B;  1TOZ A;  2WFX B;  3QMO A;  4MMY B;  5CKQ A;  3N8Y B;  1TPG A;  3NT1 A;  1UZQ A;  1FE2 A;  3BT1 A;  3TH3 L;  1G1S A;  3F6U L;  2P94 L;  1XFE A;  1I0U A;  4D90 A;  3LIW B;  2VWL L;  3SW2 A;  1HRE A;  2FLR L;  2FLB L;  5EGM B;  4RRZ A;  4ZH8 B;  1LPZ A;  1JBU L;  3GCX E;  1U67 A;  1XKB A;  1DQB A;  2WFT A;  4CUD A;  1IGX A;  4NGA L;  1IOE L;  3RR3 A;  2RA0 L;  3GCW E;  1ADX A;  1K37 A;  1JL9 A;  2J95 B;  1NFX B;  2BMG A;  1A3P A;  5CIS A;  1ATE A;  2Y81 B;  2W3I B;  2XBX L;  3KL6 B;  1IQL L;  1UZK A;  1F7M A;  3TZI A;  4AQT A;  1MQ5 L;  2W2O E;  2OYE P;  1IQE L;  4PH9 A;  1WHE A;  3KCG L;  4BXW A;  2J38 B;  3N8X A;  2BO2 A;  2Y7Z B;  4Y71 B;  1ATA A;  2P16 L;  3FCS B;  3SOB B;  4JYU L;  2WYJ B;  3C9A C;  1HX2 A;  5E8D A;  4Y7B B;  2Y5G L;  2NPR A;  3ASI A;  2XC0 L;  4JZF L;  3KQB L;  1LMM A;  2VVC K;  2BOX A;  1CX2 A;  1YUF A;  3IJE B;  3ELA L;  3M37 L;  2WZP P;  5K0H B;  1AUT L;  3OLU A;  4BTT A;  1EAI C;  3ZYI B;  2J4I B;  1IGZ A;  2B7D L;  1KLI L;  1GK5 A;  3V65 B;  4BDW A;  2BOU A;  5IKT A;  3Q7D A;  1F0S B;  1Z6E L;  3CS7 L;  1IQM L;  2FZZ L;  2P26 A;  5IKV A;  2MGP A;  4Y76 B;  3HO3 A;  5F19 A;  3LC5 B;  2H9E L;  4TGF A;  2I9A A;  2ADX A;  2P93 L;  3QH0 A;  3M36 L;  1LPG A;  4YT7 L;  4D0E A;  2K2T A;  4Z0K B;  1EQH A;  4FM5 A;  2Y38 A;  5JB8 E;  1ATD A;  2EI8 B;  1DDX A;  1CQE A;  3KK6 A;  1FAK L;  4ZXY L;  4CSY A;  4JZE L;  1N1I A;  1XKA L;  1LQD A;  1IJQ A;  3MDL A;  3NTG A;  1F0R B;  1LPK A;  1IP0 A;  3TK5 B;  1JV2 B;  2TGF A;  2VWM K;  3HO4 A;  2JKH L;  4Z0L A;  4CUF A;  5JBC E;  5KN5 C;  1YO8 A;  5JB9 E;  2P3T A;  4LMF A;  5JVY A;  2YGO A;  3QCW A;  1IQI L;  1NFW B;  1XDT R;  2WPJ E;  1EQG A;  3Q3K B;  1IQH L;  1L5G B;  1TLE A;  1EPG A;  2WYG B;  3LC3 B;  1EGF A;  1K36 A;  1HRF A;  1B9W A;  1NT0 A;  2XC4 L;  3DEM A;  2H9E C;  4Y79 B;  1YUK B;  1IQF L;  4CUE A;  1OB1 C;  3FFG L;  2W86 A;  3FBY A;  1FSB A;  5JVZ A;  2P3F L;  4NA9 L;  5CKN A;  1P9J A;  3LTF B;  4LOR A;  1NFY B;  2OYU P;  3LAQ A;  2EI7 B;  3N8Z A;  4YT6 L;  1FF7 A;  3KQD L;  2I9B A;  1DX5 I;  3S6X A;  4ZAE B;  2KL7 A;  2Q1J B;  1EPH A;  1CCF A;  2W2N E;  3ZYG A;  1PTH A;  1FAX L;  3P5B L;  2K2S B;  2WPI E;  4OTJ A;  3HS6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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