2W2OE

Pcsk9-deltac d374y mutant bound to wt egf-a of ldlr
Total Genus 8
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
47
structure length
47
Chain Sequence
LYFQGAMGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants.
pubmed doi rcsb
molecule tags Hydrolase/receptor
source organism Homo sapiens
molecule keywords PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
total genus 8
structure length 47
sequence length 47
ec nomenclature
pdb deposition date 2008-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF12662 cEGF Complement Clr-like EGF-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2w2oE00
3HPTA 2Y38A 2XC0L 1LQDA 2W86A 2WPJE 1HX2A 2W2NE 2W2QE 2FD6A 5E8DA 2P16L 2VWNL 2OYEP 1CQEA 3NTGA 1FE2A 1F7EA 1NPEB 2P94L 6COXA 4OTYA 1WHFA 2FLRL 4G1MB 2YGOA 1EQGA 1IVOC 2UWLB 4NG9L 4BTIA 1IOXA 4FM5A 4Y7BB 4Y71B 2WYJB 3LC5B 2Y81B 4RS0A 2OYUP 2WPLE 2W26B 4O02B 4Z6AL 5CKQA 2K2TA 4M10A 1PTHA 2XBYL 4D0FA 3Q7DA 1GK5A 3U73A 5COXA 1JBUL 3N8XA 3ZYGA 2EI6B 5CKNA 2BOXA 2XBXL 1DX5I 1HCGB 2Q1JB 1F0RB 2J95B 3FCSB 2W2ME 2BQ7A 3N8ZA 1HT8A 2XBWL 1APOA 3EGFA 2KL7A 3TK5B 1FF7A 3V65B 1MOXC 2WG3C 1IP0A 1NZIA 1EBVA 4X8SL 1NQLB 1N7DA 1IQKL 3SOQA 4BXSA 2P3TA 4YT6L 1FSBA 3KK6A 1IQIL 3KL6B 2TGFA 1EMNA 1RFNB 1DQBA 3CA7A 5L30L 3MQEA 3IJEB 1L3YA 2VWLL 3BT1A 4JZDL 5IKTA 1URKA 2I9AA 4BDXA 3R05A 4XBMA 3POYA 4BTUA 1O5DL 2P95L 3BPSE 3GISX 4NGAL 3N8YB 2Y82B 1NFUB 3KCGL 1KLJL 2P3UA 3DEMA 3MDLA 3TZIA 1JL9A 1Q4GA 3SOVA 3TH3L 4Z0LA 3HS6A 1N1IA 3QCWA 1NFXB 4RUTA 1W7XL 1TPGA 5K0HB 2D1JB 1X7AL 4X8VL 3NT1A 1LPZA 2VVVL 3LC3B 5KIRA 2KB9A 4JZFL 2VVUL 1ADXA 2P93L 3H5CB 2YGPA 3LTGD 3ASIA 1TLEA 2M74A 2WPKE 4RRYA 2FZZL 4ZHAB 1FAXL 5F1AA 5IKVA 2RNLA 1PRHA 3CFWA 2Y7XB 3LN0A 3M36L 3HS7A 3LIWB 1HREA 2F9BL 4BXWA 3ELAL 4M11A 3CENL 1DVAL 1G1QA 4YZUB 2VH6B 5CKMA 3U7UG 2MGRA 1PFXL 1ATEA 2Y5FL 1KLOA 3HS5A 1OB1C 4CUDA 3OLUA 2WFTA 4MMXB 3KQEL 1APQA 4YT7L 1Z6EL 2WYGB 1AUTL 3HO4A 3F6UL 1IGXA 4CSYA 2VJ3A 2J34B 4BTTA 3TBDA 1NFYB 1NFWB 1NT0A 5IKQA 1HRFA 1WU1B 1U8CB 1EPJA 2BOKL 2CJIB 5KN5C 4E1GA 1G1SA 5JB9E 5L2ZL 4OTJA 5EGMB 1CEJA 1HZ8A 1M1XB 3SW2A 1F0SB 3FBYA 1MQ6L 1EZQB 2BOHA 1L5GB 1ATDA 2UWPB 4COXA 3N8YA 3M37L 1G1TA 1K36A 1LPKA 4LORA 4TGFA 1XKAL 2I9BA 3LTFB 3N8WA 3IITB 2Y5HL 2VWOL 2XC5L 1HAEA 4Y79B 4ZXYL 1QFKL 3FFGL 1XDTR 4JZEL 5CISA 1JV2B 1YO8A 1DDXA 2K2SB 3HO5A 3NTBA 1TOZA 1UZQA 1IQJL 5JVZA 4Y6DB 3N8WB 4LMFA 3QMOA 1KSNB 2J2UB 4BDWA 4D90A 1U67A 2RA0L 1EAIC 1FJSL 2BO2A 5F19A 1EPIA 2W3KB 4JYUL 2Y5GL 1CVWL 3C9AC 1G1RA 2J4IB 2J38B 1PXXA 1I0UA 3CS7L 1IJQA 1UZPA 1G2LB 4ISHL 3ENSA 1F7MA 4XL1A 2W2OE 3LN1A 2FLGA 1UZJA 2WG4B 1KIGL 1ATBA 4ZH8B 1YUKB 1FFMA 1HAFA 1EMOA 2P28B 2WPHE 1EQHA 1YGCL 1WHEA 3QH0A 1CCVA 2BOUA 1IQNL 2P3FL 3K9XA 3V64C 2G00L 1XKBA 1XFEA 1EPGA 4ZAEB 4D0EA 5FDQA 2PR3B 1IQFL 1A3PA 1B9WA 2UWOB 2KV4A 5I46L 4Y7AB 1FAKL 1MQ5L 4AQTA 3TGFA 4PH9A 2P3FN 2Y7ZB 4XLWA 2PUQL 2RHPA 1UZKA 2EI7B 2MHPA 1ZAQA 2BMGA 3TK6B 4Z0KB 1IQGL 2VVCK 3GCWE 1Z6CA 3GCXE 3N8VA 2XC4L 1C5MF 4CUEA 2H9EL 1KLIL 2GD4A 4Y76B 3KQDL 1IQEL 4X8TL 1EPHA 1CVUA 2AYLA 1G2MB 2ADXA 2J94B 2WPME 5JVYA 1CX2A 3F1SB 4MMZB 5JB8E 2WPIE 3HO3A 4RRXA 1BF9A 1HT5A 2MGPA 4RRWA 2WFXB 1V3XB 1ATAA 1LPGA 4JYVL 4ZXXL 5IKRA 3KRKA 2VWMK 4O1ZA 3ZYIB 1LMJA 1YUFA 1DIYA 2DDUA 1SZBA 3NJPC 5JBAE 2BQ6A 1K37A 3BT2A 5L2YL 3OLTA 4CUFA 3RR3A 1W8BL 1P0SL 2BQWA 2XBVL 2EI8B 2W3IB 2W2PE 4RRZA 5JBCE 5JW1A 4MMYB 4NA9L 3P5BL 3LAQA 2VH0B 1IQML 1IGZA 3KQBL 4ISIL 1PGEA 5JBBE 2B7DL 3SOBB 1CCFA 1P9JA 2Y80B 3ZYJB 2FLBL 2JKHL 3KQCL 1IQLL 1COUA 4C16A 2NPRA 3Q3KB 2P26A 1HJ7A 1EGFA 1IOEL 1IQHL 2BZ6L 4A7IA 4X8UL 3PGHA 1J9CL 2PHBB 1YUGA
chains in the Genus database with same CATH superfamily
3HPTA 2Y38A 2XC0L 1LQDA 2W86A 2WPJE 1HX2A 2W2NE 2W2QE 2FD6A 5E8DA 2P16L 1LMMA 2VWNL 2OYEP 1CQEA 3NTGA 1FE2A 1F7EA 1NPEB 2P94L 6COXA 4OTYA 1WHFA 2FLRL 4G1MB 2YGOA 1EQGA 1IVOC 2UWLB 4NG9L 4BTIA 1IOXA 4FM5A 4Y7BB 4Y71B 2WYJB 3LC5B 2Y81B 4RS0A 2OYUP 2WPLE 2W26B 4O02B 4Z6AL 5CKQA 2K2TA 4M10A 1PTHA 2XBYL 4D0FA 3Q7DA 4GU4A 1GK5A 3U73A 5COXA 1JBUL 3N8XA 3ZYGA 2EI6B 5CKNA 2BOXA 2XBXL 1DX5I 1HCGB 2Q1JB 1F0RB 2J95B 3FCSB 2W2ME 2BQ7A 1HT8A 3N8ZA 2XBWL 1APOA 3EGFA 2KL7A 3TK5B 1FF7A 3V65B 1MOXC 2WG3C 1IP0A 1NZIA 1EBVA 4X8SL 1NQLB 1N7DA 1IQKL 3SOQA 4BXSA 2P3TA 4YT6L 1FSBA 3KK6A 1IQIL 3KL6B 2TGFA 1EMNA 1RFNB 1DQBA 3CA7A 5L30L 3MQEA 3IJEB 1L3YA 2VWLL 3BT1A 4JZDL 5IKTA 1URKA 2I9AA 4BDXA 3R05A 4XBMA 3POYA 4BTUA 1O5DL 2P95L 3BPSE 3GISX 4NGAL 3N8YB 2Y82B 1NFUB 3KCGL 1KLJL 2P3UA 3DEMA 3MDLA 3TZIA 1JL9A 1Q4GA 3SOVA 3TH3L 4Z0LA 3HS6A 1N1IA 3QCWA 1NFXB 4RUTA 2WZPP 1W7XL 1TPGA 5K0HB 2D1JB 1X7AL 4X8VL 3NT1A 1LPZA 2VVVL 3LC3B 5KIRA 2KB9A 4JZFL 2VVUL 1ADXA 2P93L 3H5CB 2YGPA 3LTGD 3ASIA 1TLEA 1KKEA 2M74A 2WPKE 4RRYA 2FZZL 4ZHAB 1FAXL 5F1AA 5IKVA 2RNLA 1PRHA 3CFWA 2Y7XB 3LN0A 3M36L 3HS7A 3LIWB 1HREA 2F9BL 4BXWA 3ELAL 4M11A 3CENL 1DVAL 1G1QA 4YZUB 2VH6B 5CKMA 3U7UG 2MGRA 1PFXL 1ATEA 2Y5FL 1KLOA 3HS5A 1OB1C 4CUDA 3OLUA 2WFTA 4MMXB 3KQEL 1APQA 4YT7L 1Z6EL 2WYGB 1AUTL 3HO4A 3F6UL 1IGXA 4CSYA 2VJ3A 2J34B 4BTTA 3TBDA 1NFYB 1NFWB 1NT0A 5IKQA 1HRFA 1WU1B 1U8CB 1EPJA 2BOKL 2CJIB 5KN5C 4E1GA 1G1SA 5JB9E 5L2ZL 4OTJA 2KNIA 5EGMB 1CEJA 1HZ8A 1M1XB 3SW2A 1F0SB 3FBYA 1MQ6L 1EZQB 2BOHA 1L5GB 1ATDA 2UWPB 1V1HA 4COXA 3S6XA 3N8YA 3M37L 1G1TA 1K36A 1LPKA 4LORA 4TGFA 1XKAL 2I9BA 3LTFB 3N8WA 3IITB 2Y5HL 2VWOL 2XC5L 1HAEA 4Y79B 4ZXYL 1QFKL 3FFGL 1XDTR 4JZEL 5CISA 1JV2B 1YO8A 1DDXA 2K2SB 3HO5A 4A94C 3NTBA 1TOZA 1UZQA 1IQJL 5JVZA 4Y6DB 3N8WB 4LMFA 4GU3A 3QMOA 1KSNB 2J2UB 4BDWA 4D90A 1U67A 2RA0L 1EAIC 1FJSL 2BO2A 5F19A 1EPIA 2W3KB 4JYUL 2Y5GL 1CVWL 3C9AC 1G1RA 2J4IB 2J38B 1PXXA 1I0UA 3CS7L 1IJQA 1UZPA 1G2LB 4ISHL 3ENSA 1F7MA 4XL1A 2W2OE 3LN1A 2FLGA 1UZJA 2WG4B 1KIGL 1ATBA 4ZH8B 1YUKB 1FFMA 1HAFA 1EMOA 2P28B 2WPHE 1EQHA 1YGCL 1WHEA 2YGQA 3QH0A 1CCVA 2BOUA 1IQNL 2P3FL 3K9XA 3V64C 2G00L 1XKBA 2BT7A 2BT8A 1XFEA 1EPGA 4ZAEB 2HORA 4D0EA 5FDQA 2PR3B 1IQFL 1A3PA 1B9WA 2UWOB 2KV4A 2BSFA 5I46L 4Y7AB 1FAKL 1MQ5L 4AQTA 3TGFA 4PH9A 2P3FN 2Y7ZB 4XLWA 2PUQL 2RHPA 1UZKA 2EI7B 2MHPA 1ZAQA 2BMGA 3TK6B 4Z0KB 1IQGL 2VVCK 3GCWE 1Z6CA 3GCXE 3N8VA 2XC4L 1C5MF 4CUEA 2H9EL 2HOXA 1KLIL 2GD4A 4Y76B 3KQDL 1IQEL 4X8TL 1EPHA 1CVUA 2AYLA 1G2MB 2ADXA 2J94B 2WPME 5JVYA 1CX2A 3F1SB 4MMZB 1LK9A 5JB8E 1V1IA 2WPIE 3HO3A 4RRXA 1BF9A 1HT5A 2MGPA 4RRWA 2WFXB 1V3XB 1ATAA 1LPGA 4JYVL 4ZXXL 5IKRA 2H9EC 3KRKA 2VWMK 4O1ZA 3ZYIB 1LMJA 1YUFA 1DIYA 2DDUA 1SZBA 3NJPC 5JBAE 2BQ6A 1K37A 3BT2A 5L2YL 3OLTA 4CUFA 3RR3A 1W8BL 2VRSA 1P0SL 2BQWA 2XBVL 2EI8B 2W3IB 2W2PE 4RRZA 5JBCE 5JW1A 4MMYB 4NA9L 3P5BL 3LAQA 2VH0B 1IQML 1QIUA 1IGZA 3KQBL 4ISIL 2JJLA 1PGEA 5JBBE 2B7DL 3SOBB 1CCFA 1P9JA 2Y80B 3ZYJB 2FLBL 2JKHL 3KQCL 1IQLL 1COUA 4C16A 2NPRA 3Q3KB 2P26A 1HJ7A 1EGFA 1IOEL 1IQHL 2BZ6L 4A7IA 4X8UL 3PGHA 1J9CL 2PHBB 1YUGA
chains in the Genus database with same CATH topology
3HPTA 2Y38A 2XC0L 1LQDA 2W86A 2WPJE 1HX2A 2W2NE 2W2QE 2FD6A 5E8DA 2P16L 1LMMA 2VWNL 2OYEP 1CQEA 3NTGA 1FE2A 1F7EA 1NPEB 2P94L 6COXA 4OTYA 1WHFA 2FLRL 4G1MB 2YGOA 1EQGA 1IVOC 2UWLB 4NG9L 4BTIA 1IOXA 4FM5A 4Y7BB 4Y71B 2WYJB 3LC5B 2Y81B 4RS0A 2OYUP 2WPLE 2W26B 4O02B 4Z6AL 5CKQA 2K2TA 4M10A 1PTHA 2XBYL 4D0FA 3Q7DA 1GK5A 3U73A 5COXA 1JBUL 3N8XA 3ZYGA 2EI6B 5CKNA 2BOXA 2XBXL 1DX5I 1HCGB 2Q1JB 1F0RB 2J95B 3FCSB 2W2ME 2BQ7A 3N8ZA 1HT8A 2XBWL 1APOA 3EGFA 2KL7A 3TK5B 1FF7A 3V65B 1MOXC 2WG3C 1IP0A 1NZIA 1EBVA 4X8SL 1NQLB 1N7DA 1IQKL 3SOQA 4BXSA 2P3TA 4YT6L 1FSBA 3KK6A 1IQIL 3KL6B 2TGFA 1EMNA 1RFNB 1DQBA 3CA7A 5L30L 3MQEA 3IJEB 1L3YA 2VWLL 3BT1A 4JZDL 5IKTA 1URKA 2I9AA 4BDXA 3R05A 4XBMA 3POYA 4BTUA 1O5DL 2P95L 3BPSE 3GISX 4NGAL 3N8YB 2Y82B 1NFUB 3KCGL 1KLJL 2P3UA 3DEMA 3MDLA 3TZIA 1JL9A 1Q4GA 3SOVA 3TH3L 4Z0LA 3HS6A 1N1IA 3QCWA 1NFXB 4RUTA 2WZPP 1W7XL 1TPGA 5K0HB 2D1JB 1X7AL 4X8VL 3NT1A 1LPZA 2VVVL 3LC3B 5KIRA 2KB9A 4JZFL 2VVUL 1ADXA 2P93L 3H5CB 2YGPA 3LTGD 3ASIA 1TLEA 2M74A 2WPKE 4RRYA 2FZZL 4ZHAB 1FAXL 5F1AA 5IKVA 2RNLA 1PRHA 3CFWA 2Y7XB 3LN0A 3M36L 3HS7A 3LIWB 1HREA 2F9BL 4BXWA 3ELAL 4M11A 3CENL 1DVAL 1G1QA 4YZUB 2VH6B 5CKMA 3U7UG 2MGRA 1PFXL 1ATEA 2Y5FL 1KLOA 3HS5A 1OB1C 4CUDA 3OLUA 2WFTA 4MMXB 3KQEL 1APQA 4YT7L 1Z6EL 2WYGB 1AUTL 3HO4A 3F6UL 1IGXA 4CSYA 2VJ3A 2J34B 4BTTA 3TBDA 1NFYB 1NFWB 1NT0A 5IKQA 1HRFA 1WU1B 1U8CB 1EPJA 2BOKL 2CJIB 5KN5C 4E1GA 1G1SA 5JB9E 5L2ZL 4OTJA 2KNIA 5EGMB 1CEJA 1HZ8A 1M1XB 3SW2A 1F0SB 3FBYA 1MQ6L 1EZQB 2BOHA 1L5GB 1ATDA 2UWPB 4COXA 3S6XA 3N8YA 3M37L 1G1TA 1K36A 1LPKA 4LORA 4TGFA 1XKAL 2I9BA 3LTFB 3N8WA 3IITB 2Y5HL 2VWOL 2XC5L 1HAEA 4Y79B 4ZXYL 1QFKL 3FFGL 1XDTR 4JZEL 5CISA 1JV2B 1YO8A 1DDXA 2K2SB 3HO5A 4A94C 3NTBA 1TOZA 1UZQA 1IQJL 5JVZA 4Y6DB 3N8WB 4LMFA 3QMOA 1KSNB 2J2UB 4BDWA 4D90A 1U67A 2RA0L 1EAIC 1FJSL 2BO2A 5F19A 1EPIA 2W3KB 4JYUL 2Y5GL 1CVWL 3C9AC 1G1RA 2J4IB 2J38B 1PXXA 1I0UA 3CS7L 1IJQA 1UZPA 1G2LB 4ISHL 3ENSA 1F7MA 4XL1A 2W2OE 3LN1A 2FLGA 1UZJA 2WG4B 1KIGL 1ATBA 4ZH8B 1YUKB 1FFMA 1HAFA 1EMOA 2P28B 2WPHE 1EQHA 1YGCL 1WHEA 2YGQA 3QH0A 1CCVA 2BOUA 1IQNL 2P3FL 3K9XA 3V64C 2G00L 1XKBA 1XFEA 1EPGA 4ZAEB 4D0EA 5FDQA 2PR3B 1IQFL 1A3PA 1B9WA 2UWOB 2KV4A 5I46L 4Y7AB 1FAKL 1MQ5L 4AQTA 3TGFA 4PH9A 2P3FN 2Y7ZB 4XLWA 2PUQL 2RHPA 1UZKA 2EI7B 2MHPA 1ZAQA 2BMGA 3TK6B 4Z0KB 1IQGL 2VVCK 3GCWE 1Z6CA 3GCXE 3N8VA 2XC4L 1C5MF 4CUEA 2H9EL 1KLIL 2GD4A 4Y76B 3KQDL 1IQEL 4X8TL 1EPHA 1CVUA 2AYLA 1G2MB 2ADXA 2J94B 2WPME 5JVYA 1CX2A 3F1SB 4MMZB 5JB8E 2WPIE 3HO3A 4RRXA 1BF9A 1HT5A 2MGPA 4RRWA 2WFXB 1V3XB 1ATAA 1LPGA 4JYVL 4ZXXL 5IKRA 2H9EC 3KRKA 2VWMK 4O1ZA 3ZYIB 1LMJA 1YUFA 1DIYA 2DDUA 1SZBA 3NJPC 5JBAE 2BQ6A 1K37A 3BT2A 5L2YL 3OLTA 4CUFA 3RR3A 1W8BL 1P0SL 2BQWA 2XBVL 2EI8B 2W3IB 2W2PE 4RRZA 5JBCE 5JW1A 4MMYB 4NA9L 3P5BL 3LAQA 2VH0B 1IQML 1IGZA 3KQBL 4ISIL 1PGEA 5JBBE 2B7DL 3SOBB 1CCFA 1P9JA 2Y80B 3ZYJB 2FLBL 2JKHL 3KQCL 1IQLL 1COUA 4C16A 2NPRA 3Q3KB 2P26A 1HJ7A 1EGFA 1IOEL 1IQHL 2BZ6L 4A7IA 4X8UL 3PGHA 1J9CL 2PHBB 1YUGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HPT A;  2Y38 A;  2XC0 L;  1LQD A;  2W86 A;  2WPJ E;  1HX2 A;  2W2N E;  2W2Q E;  2FD6 A;  5E8D A;  2P16 L;  2VWN L;  2OYE P;  1CQE A;  3NTG A;  1FE2 A;  1F7E A;  1NPE B;  2P94 L;  6COX A;  4OTY A;  1WHF A;  2FLR L;  4G1M B;  2YGO A;  1EQG A;  1IVO C;  2UWL B;  4NG9 L;  4BTI A;  1IOX A;  4FM5 A;  4Y7B B;  4Y71 B;  2WYJ B;  3LC5 B;  2Y81 B;  4RS0 A;  2OYU P;  2WPL E;  2W26 B;  4O02 B;  4Z6A L;  5CKQ A;  2K2T A;  4M10 A;  1PTH A;  2XBY L;  4D0F A;  3Q7D A;  1GK5 A;  3U73 A;  5COX A;  1JBU L;  3N8X A;  3ZYG A;  2EI6 B;  5CKN A;  2BOX A;  2XBX L;  1DX5 I;  1HCG B;  2Q1J B;  1F0R B;  2J95 B;  3FCS B;  2W2M E;  2BQ7 A;  3N8Z A;  1HT8 A;  2XBW L;  1APO A;  3EGF A;  2KL7 A;  3TK5 B;  1FF7 A;  3V65 B;  1MOX C;  2WG3 C;  1IP0 A;  1NZI A;  1EBV A;  4X8S L;  1NQL B;  1N7D A;  1IQK L;  3SOQ A;  4BXS A;  2P3T A;  4YT6 L;  1FSB A;  3KK6 A;  1IQI L;  3KL6 B;  2TGF A;  1EMN A;  1RFN B;  1DQB A;  3CA7 A;  5L30 L;  3MQE A;  3IJE B;  1L3Y A;  2VWL L;  3BT1 A;  4JZD L;  5IKT A;  1URK A;  2I9A A;  4BDX A;  3R05 A;  4XBM A;  3POY A;  4BTU A;  1O5D L;  2P95 L;  3BPS E;  3GIS X;  4NGA L;  3N8Y B;  2Y82 B;  1NFU B;  3KCG L;  1KLJ L;  2P3U A;  3DEM A;  3MDL A;  3TZI A;  1JL9 A;  1Q4G A;  3SOV A;  3TH3 L;  4Z0L A;  3HS6 A;  1N1I A;  3QCW A;  1NFX B;  4RUT A;  1W7X L;  1TPG A;  5K0H B;  2D1J B;  1X7A L;  4X8V L;  3NT1 A;  1LPZ A;  2VVV L;  3LC3 B;  5KIR A;  2KB9 A;  4JZF L;  2VVU L;  1ADX A;  2P93 L;  3H5C B;  2YGP A;  3LTG D;  3ASI A;  1TLE A;  2M74 A;  2WPK E;  4RRY A;  2FZZ L;  4ZHA B;  1FAX L;  5F1A A;  5IKV A;  2RNL A;  1PRH A;  3CFW A;  2Y7X B;  3LN0 A;  3M36 L;  3HS7 A;  3LIW B;  1HRE A;  2F9B L;  4BXW A;  3ELA L;  4M11 A;  3CEN L;  1DVA L;  1G1Q A;  4YZU B;  2VH6 B;  5CKM A;  3U7U G;  2MGR A;  1PFX L;  1ATE A;  2Y5F L;  1KLO A;  3HS5 A;  1OB1 C;  4CUD A;  3OLU A;  2WFT A;  4MMX B;  3KQE L;  1APQ A;  4YT7 L;  1Z6E L;  2WYG B;  1AUT L;  3HO4 A;  3F6U L;  1IGX A;  4CSY A;  2VJ3 A;  2J34 B;  4BTT A;  3TBD A;  1NFY B;  1NFW B;  1NT0 A;  5IKQ A;  1HRF A;  1WU1 B;  1U8C B;  1EPJ A;  2BOK L;  2CJI B;  5KN5 C;  4E1G A;  1G1S A;  5JB9 E;  5L2Z L;  4OTJ A;  5EGM B;  1CEJ A;  1HZ8 A;  1M1X B;  3SW2 A;  1F0S B;  3FBY A;  1MQ6 L;  1EZQ B;  2BOH A;  1L5G B;  1ATD A;  2UWP B;  4COX A;  3N8Y A;  3M37 L;  1G1T A;  1K36 A;  1LPK A;  4LOR A;  4TGF A;  1XKA L;  2I9B A;  3LTF B;  3N8W A;  3IIT B;  2Y5H L;  2VWO L;  2XC5 L;  1HAE A;  4Y79 B;  4ZXY L;  1QFK L;  3FFG L;  1XDT R;  4JZE L;  5CIS A;  1JV2 B;  1YO8 A;  1DDX A;  2K2S B;  3HO5 A;  3NTB A;  1TOZ A;  1UZQ A;  1IQJ L;  5JVZ A;  4Y6D B;  3N8W B;  4LMF A;  3QMO A;  1KSN B;  2J2U B;  4BDW A;  4D90 A;  1U67 A;  2RA0 L;  1EAI C;  1FJS L;  2BO2 A;  5F19 A;  1EPI A;  2W3K B;  4JYU L;  2Y5G L;  1CVW L;  3C9A C;  1G1R A;  2J4I B;  2J38 B;  1PXX A;  1I0U A;  3CS7 L;  1IJQ A;  1UZP A;  1G2L B;  4ISH L;  3ENS A;  1F7M A;  4XL1 A;  2W2O E;  3LN1 A;  2FLG A;  1UZJ A;  2WG4 B;  1KIG L;  1ATB A;  4ZH8 B;  1YUK B;  1FFM A;  1HAF A;  1EMO A;  2P28 B;  2WPH E;  1EQH A;  1YGC L;  1WHE A;  3QH0 A;  1CCV A;  2BOU A;  1IQN L;  2P3F L;  3K9X A;  3V64 C;  2G00 L;  1XKB A;  1XFE A;  1EPG A;  4ZAE B;  4D0E A;  5FDQ A;  2PR3 B;  1IQF L;  1A3P A;  1B9W A;  2UWO B;  2KV4 A;  5I46 L;  4Y7A B;  1FAK L;  1MQ5 L;  4AQT A;  3TGF A;  4PH9 A;  2P3F N;  2Y7Z B;  4XLW A;  2PUQ L;  2RHP A;  1UZK A;  2EI7 B;  2MHP A;  1ZAQ A;  2BMG A;  3TK6 B;  4Z0K B;  1IQG L;  2VVC K;  3GCW E;  1Z6C A;  3GCX E;  3N8V A;  2XC4 L;  1C5M F;  4CUE A;  2H9E L;  1KLI L;  2GD4 A;  4Y76 B;  3KQD L;  1IQE L;  4X8T L;  1EPH A;  1CVU A;  2AYL A;  1G2M B;  2ADX A;  2J94 B;  2WPM E;  5JVY A;  1CX2 A;  3F1S B;  4MMZ B;  5JB8 E;  2WPI E;  3HO3 A;  4RRX A;  1BF9 A;  1HT5 A;  2MGP A;  4RRW A;  2WFX B;  1V3X B;  1ATA A;  1LPG A;  4JYV L;  4ZXX L;  5IKR A;  3KRK A;  2VWM K;  4O1Z A;  3ZYI B;  1LMJ A;  1YUF A;  1DIY A;  2DDU A;  1SZB A;  3NJP C;  5JBA E;  2BQ6 A;  1K37 A;  3BT2 A;  5L2Y L;  3OLT A;  4CUF A;  3RR3 A;  1W8B L;  1P0S L;  2BQW A;  2XBV L;  2EI8 B;  2W3I B;  2W2P E;  4RRZ A;  5JBC E;  5JW1 A;  4MMY B;  4NA9 L;  3P5B L;  3LAQ A;  2VH0 B;  1IQM L;  1IGZ A;  3KQB L;  4ISI L;  1PGE A;  5JBB E;  2B7D L;  3SOB B;  1CCF A;  1P9J A;  2Y80 B;  3ZYJ B;  2FLB L;  2JKH L;  3KQC L;  1IQL L;  1COU A;  4C16 A;  2NPR A;  3Q3K B;  2P26 A;  1HJ7 A;  1EGF A;  1IOE L;  1IQH L;  2BZ6 L;  4A7I A;  4X8U L;  3PGH A;  1J9C L;  2PHB B;  1YUG A; 
#chains in the Genus database with same CATH topology
 3HPT A;  2Y38 A;  2XC0 L;  1LQD A;  2W86 A;  2WPJ E;  1HX2 A;  2W2N E;  2W2Q E;  2FD6 A;  5E8D A;  2P16 L;  1LMM A;  2VWN L;  2OYE P;  1CQE A;  3NTG A;  1FE2 A;  1F7E A;  1NPE B;  2P94 L;  6COX A;  4OTY A;  1WHF A;  2FLR L;  4G1M B;  2YGO A;  1EQG A;  1IVO C;  2UWL B;  4NG9 L;  4BTI A;  1IOX A;  4FM5 A;  4Y7B B;  4Y71 B;  2WYJ B;  3LC5 B;  2Y81 B;  4RS0 A;  2OYU P;  2WPL E;  2W26 B;  4O02 B;  4Z6A L;  5CKQ A;  2K2T A;  4M10 A;  1PTH A;  2XBY L;  4D0F A;  3Q7D A;  4GU4 A;  1GK5 A;  3U73 A;  5COX A;  1JBU L;  3N8X A;  3ZYG A;  2EI6 B;  5CKN A;  2BOX A;  2XBX L;  1DX5 I;  1HCG B;  2Q1J B;  1F0R B;  2J95 B;  3FCS B;  2W2M E;  2BQ7 A;  1HT8 A;  3N8Z A;  2XBW L;  1APO A;  3EGF A;  2KL7 A;  3TK5 B;  1FF7 A;  3V65 B;  1MOX C;  2WG3 C;  1IP0 A;  1NZI A;  1EBV A;  4X8S L;  1NQL B;  1N7D A;  1IQK L;  3SOQ A;  4BXS A;  2P3T A;  4YT6 L;  1FSB A;  3KK6 A;  1IQI L;  3KL6 B;  2TGF A;  1EMN A;  1RFN B;  1DQB A;  3CA7 A;  5L30 L;  3MQE A;  3IJE B;  1L3Y A;  2VWL L;  3BT1 A;  4JZD L;  5IKT A;  1URK A;  2I9A A;  4BDX A;  3R05 A;  4XBM A;  3POY A;  4BTU A;  1O5D L;  2P95 L;  3BPS E;  3GIS X;  4NGA L;  3N8Y B;  2Y82 B;  1NFU B;  3KCG L;  1KLJ L;  2P3U A;  3DEM A;  3MDL A;  3TZI A;  1JL9 A;  1Q4G A;  3SOV A;  3TH3 L;  4Z0L A;  3HS6 A;  1N1I A;  3QCW A;  1NFX B;  4RUT A;  2WZP P;  1W7X L;  1TPG A;  5K0H B;  2D1J B;  1X7A L;  4X8V L;  3NT1 A;  1LPZ A;  2VVV L;  3LC3 B;  5KIR A;  2KB9 A;  4JZF L;  2VVU L;  1ADX A;  2P93 L;  3H5C B;  2YGP A;  3LTG D;  3ASI A;  1TLE A;  1KKE A;  2M74 A;  2WPK E;  4RRY A;  2FZZ L;  4ZHA B;  1FAX L;  5F1A A;  5IKV A;  2RNL A;  1PRH A;  3CFW A;  2Y7X B;  3LN0 A;  3M36 L;  3HS7 A;  3LIW B;  1HRE A;  2F9B L;  4BXW A;  3ELA L;  4M11 A;  3CEN L;  1DVA L;  1G1Q A;  4YZU B;  2VH6 B;  5CKM A;  3U7U G;  2MGR A;  1PFX L;  1ATE A;  2Y5F L;  1KLO A;  3HS5 A;  1OB1 C;  4CUD A;  3OLU A;  2WFT A;  4MMX B;  3KQE L;  1APQ A;  4YT7 L;  1Z6E L;  2WYG B;  1AUT L;  3HO4 A;  3F6U L;  1IGX A;  4CSY A;  2VJ3 A;  2J34 B;  4BTT A;  3TBD A;  1NFY B;  1NFW B;  1NT0 A;  5IKQ A;  1HRF A;  1WU1 B;  1U8C B;  1EPJ A;  2BOK L;  2CJI B;  5KN5 C;  4E1G A;  1G1S A;  5JB9 E;  5L2Z L;  4OTJ A;  2KNI A;  5EGM B;  1CEJ A;  1HZ8 A;  1M1X B;  3SW2 A;  1F0S B;  3FBY A;  1MQ6 L;  1EZQ B;  2BOH A;  1L5G B;  1ATD A;  2UWP B;  1V1H A;  4COX A;  3S6X A;  3N8Y A;  3M37 L;  1G1T A;  1K36 A;  1LPK A;  4LOR A;  4TGF A;  1XKA L;  2I9B A;  3LTF B;  3N8W A;  3IIT B;  2Y5H L;  2VWO L;  2XC5 L;  1HAE A;  4Y79 B;  4ZXY L;  1QFK L;  3FFG L;  1XDT R;  4JZE L;  5CIS A;  1JV2 B;  1YO8 A;  1DDX A;  2K2S B;  3HO5 A;  4A94 C;  3NTB A;  1TOZ A;  1UZQ A;  1IQJ L;  5JVZ A;  4Y6D B;  3N8W B;  4LMF A;  4GU3 A;  3QMO A;  1KSN B;  2J2U B;  4BDW A;  4D90 A;  1U67 A;  2RA0 L;  1EAI C;  1FJS L;  2BO2 A;  5F19 A;  1EPI A;  2W3K B;  4JYU L;  2Y5G L;  1CVW L;  3C9A C;  1G1R A;  2J4I B;  2J38 B;  1PXX A;  1I0U A;  3CS7 L;  1IJQ A;  1UZP A;  1G2L B;  4ISH L;  3ENS A;  1F7M A;  4XL1 A;  2W2O E;  3LN1 A;  2FLG A;  1UZJ A;  2WG4 B;  1KIG L;  1ATB A;  4ZH8 B;  1YUK B;  1FFM A;  1HAF A;  1EMO A;  2P28 B;  2WPH E;  1EQH A;  1YGC L;  1WHE A;  2YGQ A;  3QH0 A;  1CCV A;  2BOU A;  1IQN L;  2P3F L;  3K9X A;  3V64 C;  2G00 L;  1XKB A;  2BT7 A;  2BT8 A;  1XFE A;  1EPG A;  4ZAE B;  2HOR A;  4D0E A;  5FDQ A;  2PR3 B;  1IQF L;  1A3P A;  1B9W A;  2UWO B;  2KV4 A;  2BSF A;  5I46 L;  4Y7A B;  1FAK L;  1MQ5 L;  4AQT A;  3TGF A;  4PH9 A;  2P3F N;  2Y7Z B;  4XLW A;  2PUQ L;  2RHP A;  1UZK A;  2EI7 B;  2MHP A;  1ZAQ A;  2BMG A;  3TK6 B;  4Z0K B;  1IQG L;  2VVC K;  3GCW E;  1Z6C A;  3GCX E;  3N8V A;  2XC4 L;  1C5M F;  4CUE A;  2H9E L;  2HOX A;  1KLI L;  2GD4 A;  4Y76 B;  3KQD L;  1IQE L;  4X8T L;  1EPH A;  1CVU A;  2AYL A;  1G2M B;  2ADX A;  2J94 B;  2WPM E;  5JVY A;  1CX2 A;  3F1S B;  4MMZ B;  1LK9 A;  5JB8 E;  1V1I A;  2WPI E;  3HO3 A;  4RRX A;  1BF9 A;  1HT5 A;  2MGP A;  4RRW A;  2WFX B;  1V3X B;  1ATA A;  1LPG A;  4JYV L;  4ZXX L;  5IKR A;  2H9E C;  3KRK A;  2VWM K;  4O1Z A;  3ZYI B;  1LMJ A;  1YUF A;  1DIY A;  2DDU A;  1SZB A;  3NJP C;  5JBA E;  2BQ6 A;  1K37 A;  3BT2 A;  5L2Y L;  3OLT A;  4CUF A;  3RR3 A;  1W8B L;  2VRS A;  1P0S L;  2BQW A;  2XBV L;  2EI8 B;  2W3I B;  2W2P E;  4RRZ A;  5JBC E;  5JW1 A;  4MMY B;  4NA9 L;  3P5B L;  3LAQ A;  2VH0 B;  1IQM L;  1QIU A;  1IGZ A;  3KQB L;  4ISI L;  2JJL A;  1PGE A;  5JBB E;  2B7D L;  3SOB B;  1CCF A;  1P9J A;  2Y80 B;  3ZYJ B;  2FLB L;  2JKH L;  3KQC L;  1IQL L;  1COU A;  4C16 A;  2NPR A;  3Q3K B;  2P26 A;  1HJ7 A;  1EGF A;  1IOE L;  1IQH L;  2BZ6 L;  4A7I A;  4X8U L;  3PGH A;  1J9C L;  2PHB B;  1YUG A; 
#chains in the Genus database with same CATH homology
 3HPT A;  2Y38 A;  2XC0 L;  1LQD A;  2W86 A;  2WPJ E;  1HX2 A;  2W2N E;  2W2Q E;  2FD6 A;  5E8D A;  2P16 L;  1LMM A;  2VWN L;  2OYE P;  1CQE A;  3NTG A;  1FE2 A;  1F7E A;  1NPE B;  2P94 L;  6COX A;  4OTY A;  1WHF A;  2FLR L;  4G1M B;  2YGO A;  1EQG A;  1IVO C;  2UWL B;  4NG9 L;  4BTI A;  1IOX A;  4FM5 A;  4Y7B B;  4Y71 B;  2WYJ B;  3LC5 B;  2Y81 B;  4RS0 A;  2OYU P;  2WPL E;  2W26 B;  4O02 B;  4Z6A L;  5CKQ A;  2K2T A;  4M10 A;  1PTH A;  2XBY L;  4D0F A;  3Q7D A;  1GK5 A;  3U73 A;  5COX A;  1JBU L;  3N8X A;  3ZYG A;  2EI6 B;  5CKN A;  2BOX A;  2XBX L;  1DX5 I;  1HCG B;  2Q1J B;  1F0R B;  2J95 B;  3FCS B;  2W2M E;  2BQ7 A;  3N8Z A;  1HT8 A;  2XBW L;  1APO A;  3EGF A;  2KL7 A;  3TK5 B;  1FF7 A;  3V65 B;  1MOX C;  2WG3 C;  1IP0 A;  1NZI A;  1EBV A;  4X8S L;  1NQL B;  1N7D A;  1IQK L;  3SOQ A;  4BXS A;  2P3T A;  4YT6 L;  1FSB A;  3KK6 A;  1IQI L;  3KL6 B;  2TGF A;  1EMN A;  1RFN B;  1DQB A;  3CA7 A;  5L30 L;  3MQE A;  3IJE B;  1L3Y A;  2VWL L;  3BT1 A;  4JZD L;  5IKT A;  1URK A;  2I9A A;  4BDX A;  3R05 A;  4XBM A;  3POY A;  4BTU A;  1O5D L;  2P95 L;  3BPS E;  3GIS X;  4NGA L;  3N8Y B;  2Y82 B;  1NFU B;  3KCG L;  1KLJ L;  2P3U A;  3DEM A;  3MDL A;  3TZI A;  1JL9 A;  1Q4G A;  3SOV A;  3TH3 L;  4Z0L A;  3HS6 A;  1N1I A;  3QCW A;  1NFX B;  4RUT A;  2WZP P;  1W7X L;  1TPG A;  5K0H B;  2D1J B;  1X7A L;  4X8V L;  3NT1 A;  1LPZ A;  2VVV L;  3LC3 B;  5KIR A;  2KB9 A;  4JZF L;  2VVU L;  1ADX A;  2P93 L;  3H5C B;  2YGP A;  3LTG D;  3ASI A;  1TLE A;  2M74 A;  2WPK E;  4RRY A;  2FZZ L;  4ZHA B;  1FAX L;  5F1A A;  5IKV A;  2RNL A;  1PRH A;  3CFW A;  2Y7X B;  3LN0 A;  3M36 L;  3HS7 A;  3LIW B;  1HRE A;  2F9B L;  4BXW A;  3ELA L;  4M11 A;  3CEN L;  1DVA L;  1G1Q A;  4YZU B;  2VH6 B;  5CKM A;  3U7U G;  2MGR A;  1PFX L;  1ATE A;  2Y5F L;  1KLO A;  3HS5 A;  1OB1 C;  4CUD A;  3OLU A;  2WFT A;  4MMX B;  3KQE L;  1APQ A;  4YT7 L;  1Z6E L;  2WYG B;  1AUT L;  3HO4 A;  3F6U L;  1IGX A;  4CSY A;  2VJ3 A;  2J34 B;  4BTT A;  3TBD A;  1NFY B;  1NFW B;  1NT0 A;  5IKQ A;  1HRF A;  1WU1 B;  1U8C B;  1EPJ A;  2BOK L;  2CJI B;  5KN5 C;  4E1G A;  1G1S A;  5JB9 E;  5L2Z L;  4OTJ A;  2KNI A;  5EGM B;  1CEJ A;  1HZ8 A;  1M1X B;  3SW2 A;  1F0S B;  3FBY A;  1MQ6 L;  1EZQ B;  2BOH A;  1L5G B;  1ATD A;  2UWP B;  4COX A;  3S6X A;  3N8Y A;  3M37 L;  1G1T A;  1K36 A;  1LPK A;  4LOR A;  4TGF A;  1XKA L;  2I9B A;  3LTF B;  3N8W A;  3IIT B;  2Y5H L;  2VWO L;  2XC5 L;  1HAE A;  4Y79 B;  4ZXY L;  1QFK L;  3FFG L;  1XDT R;  4JZE L;  5CIS A;  1JV2 B;  1YO8 A;  1DDX A;  2K2S B;  3HO5 A;  4A94 C;  3NTB A;  1TOZ A;  1UZQ A;  1IQJ L;  5JVZ A;  4Y6D B;  3N8W B;  4LMF A;  3QMO A;  1KSN B;  2J2U B;  4BDW A;  4D90 A;  1U67 A;  2RA0 L;  1EAI C;  1FJS L;  2BO2 A;  5F19 A;  1EPI A;  2W3K B;  4JYU L;  2Y5G L;  1CVW L;  3C9A C;  1G1R A;  2J4I B;  2J38 B;  1PXX A;  1I0U A;  3CS7 L;  1IJQ A;  1UZP A;  1G2L B;  4ISH L;  3ENS A;  1F7M A;  4XL1 A;  2W2O E;  3LN1 A;  2FLG A;  1UZJ A;  2WG4 B;  1KIG L;  1ATB A;  4ZH8 B;  1YUK B;  1FFM A;  1HAF A;  1EMO A;  2P28 B;  2WPH E;  1EQH A;  1YGC L;  1WHE A;  2YGQ A;  3QH0 A;  1CCV A;  2BOU A;  1IQN L;  2P3F L;  3K9X A;  3V64 C;  2G00 L;  1XKB A;  1XFE A;  1EPG A;  4ZAE B;  4D0E A;  5FDQ A;  2PR3 B;  1IQF L;  1A3P A;  1B9W A;  2UWO B;  2KV4 A;  5I46 L;  4Y7A B;  1FAK L;  1MQ5 L;  4AQT A;  3TGF A;  4PH9 A;  2P3F N;  2Y7Z B;  4XLW A;  2PUQ L;  2RHP A;  1UZK A;  2EI7 B;  2MHP A;  1ZAQ A;  2BMG A;  3TK6 B;  4Z0K B;  1IQG L;  2VVC K;  3GCW E;  1Z6C A;  3GCX E;  3N8V A;  2XC4 L;  1C5M F;  4CUE A;  2H9E L;  1KLI L;  2GD4 A;  4Y76 B;  3KQD L;  1IQE L;  4X8T L;  1EPH A;  1CVU A;  2AYL A;  1G2M B;  2ADX A;  2J94 B;  2WPM E;  5JVY A;  1CX2 A;  3F1S B;  4MMZ B;  5JB8 E;  2WPI E;  3HO3 A;  4RRX A;  1BF9 A;  1HT5 A;  2MGP A;  4RRW A;  2WFX B;  1V3X B;  1ATA A;  1LPG A;  4JYV L;  4ZXX L;  5IKR A;  2H9E C;  3KRK A;  2VWM K;  4O1Z A;  3ZYI B;  1LMJ A;  1YUF A;  1DIY A;  2DDU A;  1SZB A;  3NJP C;  5JBA E;  2BQ6 A;  1K37 A;  3BT2 A;  5L2Y L;  3OLT A;  4CUF A;  3RR3 A;  1W8B L;  1P0S L;  2BQW A;  2XBV L;  2EI8 B;  2W3I B;  2W2P E;  4RRZ A;  5JBC E;  5JW1 A;  4MMY B;  4NA9 L;  3P5B L;  3LAQ A;  2VH0 B;  1IQM L;  1IGZ A;  3KQB L;  4ISI L;  1PGE A;  5JBB E;  2B7D L;  3SOB B;  1CCF A;  1P9J A;  2Y80 B;  3ZYJ B;  2FLB L;  2JKH L;  3KQC L;  1IQL L;  1COU A;  4C16 A;  2NPR A;  3Q3K B;  2P26 A;  1HJ7 A;  1EGF A;  1IOE L;  1IQH L;  2BZ6 L;  4A7I A;  4X8U L;  3PGH A;  1J9C L;  2PHB B;  1YUG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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