2W2QE

Pcsk9-deltac d374h mutant bound to wt egf-a of ldlr
Total Genus 8
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
47
structure length
47
Chain Sequence
LYFQGAMGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants.
pubmed doi rcsb
molecule tags Hydrolase/receptor
source organism Homo sapiens
molecule keywords PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
total genus 8
structure length 47
sequence length 47
ec nomenclature
pdb deposition date 2008-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF12662 cEGF Complement Clr-like EGF-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2w2qE00
3KQEL 1W8BL 1KLOA 4YZUB 3N8VA 2W86A 1FJSL 4X8TL 3BPSE 1CVUA 2K2SB 2XBVL 4OTJA 4BXWA 1FSBA 1CCVA 1ATBA 2WFTA 2BMGA 5F19A 2I9BA 4G1MB 4NGAL 2W2NE 1FAXL 2W3KB 1EQGA 3QH0A 1WHEA 2FLBL 2J34B 3SW2A 1N7DA 1DIYA 1G2MB 2K2TA 4CUDA 1EPGA 1OB1C 4ZH8B 3LC3B 3POYA 2UWOB 4X8VL 2FLGA 1ADXA 3TZIA 1GK5A 1YUKB 5L30L 4Y76B 1FE2A 1CEJA 4CUFA 2UWLB 3HO4A 1G1QA 1PGEA 2VJ3A 5IKRA 1HREA 1YUGA 2OYEP 2W2QE 2Y7XB 4D0EA 3HPTA 4RRWA 4BTTA 1EPIA 4XBMA 5CISA 2P95L 3CS7L 4XLWA 1HZ8A 1APOA 3V65B 1P9JA 3GCXE 4O02B 5EGMB 3OLUA 1KLIL 3LTFB 1HT5A 2P3FL 1QFKL 1XKAL 1X7AL 2ADXA 2B7DL 2XC5L 1G1TA 4Z0LA 4Y7BB 3NT1A 1YUFA 4BTUA 1NFXB 4XL1A 1XDTR 4Y7AB 2Y5HL 4YT6L 3FCSB 4MMYB 2MHPA 1Z6CA 3H5CB 3N8YB 1K36A 4RUTA 4CUEA 1PRHA 2VVUL 3KRKA 1DQBA 2NPRA 1LQDA 1HCGB 1UZJA 4RRXA 1IQFL 4E1GA 3F6UL 2W2ME 3N8WB 3CFWA 2XC0L 4ZAEB 4X8UL 3BT1A 2BQWA 3TK5B 3U7UG 2P3FN 5JVYA 2J4IB 4FM5A 1KIGL 5JBBE 2BO2A 1HAEA 1NZIA 4ZXYL 2KL7A 3K9XA 2D1JB 2WYGB 2WG4B 1LPGA 1IGZA 3HS7A 2FZZL 3DEMA 3KQBL 1IP0A 2WYJB 2VWLL 2WPIE 1IQHL 1U8CB 1TLEA 5IKQA 3TGFA 1U67A 2EI7B 1G2LB 2BOUA 1O5DL 1COUA 1UZQA 1Z6EL 5JB9E 4Z6AL 1K37A 3ASIA 4COXA 3LIWB 3TK6B 2BOKL 2PHBB 3KL6B 1LMJA 3SOQA 1JL9A 1NFUB 3Q7DA 1G1SA 3N8YA 3ZYJB 1P0SL 2P16L 2KB9A 4LORA 2WPLE 3MQEA 1CQEA 2WFXB 1KSNB 2I9AA 5JBCE 5COXA 3EGFA 3KK6A 2VWMK 2UWPB 3N8XA 3N8WA 2G00L 3LN0A 3NTGA 1DVAL 3TBDA 2VVVL 1YO8A 2P28B 1F7MA 3F1SB 1BF9A 1UZKA 3KQCL 3CA7A 1IVOC 1B9WA 1RFNB 5CKMA 1HRFA 1IQLL 4JYVL 3NTBA 1FFMA 1NPEB 1FF7A 1URKA 2RHPA 1DDXA 4JYUL 2Y5FL 5L2ZL 2XBYL 2WPKE 4BDWA 3ZYIB 1CCFA 1PTHA 2DDUA 5IKVA 4M11A 2P3UA 1J9CL 1EGFA 3SOVA 3OLTA 5K0HB 4BDXA 3TH3L 2F9BL 4RRZA 1EBVA 2EI6B 2TGFA 1NT0A 1LPZA 1MQ6L 2P93L 2Y7ZB 3QMOA 3SOBB 2Y5GL 1TOZA 2BOXA 1G1RA 2FLRL 3N8ZA 5IKTA 4Y71B 4YT7L 2EI8B 1HJ7A 2Y82B 1KLJL 4RS0A 2MGRA 1HX2A 1APQA 2BOHA 4Y79B 1YGCL 1ATAA 2WPME 4OTYA 2W3IB 1EPJA 1HT8A 1MQ5L 1PXXA 1EMNA 1NFWB 5JBAE 1PFXL 5FDQA 1F0SB 5KN5C 1DX5I 1TPGA 2WPHE 4ISIL 1IOXA 2W26B 3PGHA 2VWOL 4BTIA 1N1IA 4RRYA 5CKQA 3HS5A 3V64C 1EQHA 1MOXC 1A3PA 4MMXB 2WG3C 3HO3A 1ZAQA 4A7IA 3LTGD 1IGXA 3M37L 1EMOA 2FD6A 2VWNL 4M10A 3MDLA 1WHFA 3FBYA 2Y80B 1IQEL 4C16A 4PH9A 1IQJL 2Y38A 2AYLA 2P94L 4TGFA 1UZPA 2W2OE 3GISX 5KIRA 1WU1B 4BXSA 2M74A 2CJIB 5JVZA 1Q4GA 1V3XB 2Q1JB 4Z0KB 2XC4L 2XBWL 1IQML 4AQTA 2RNLA 1XFEA 5F1AA 1IJQA 2J2UB 1L3YA 4MMZB 2J95B 3ENSA 1NQLB 4ZHAB 2WPJE 2J94B 2KV4A 1JV2B 2W2PE 1JBUL 1ATEA 3C9AC 3U73A 1IQNL 3P5BL 1IQKL 3GCWE 4NA9L 4Y6DB 1AUTL 2Y81B 1EZQB 3M36L 3IITB 2VH0B 3CENL 3LAQA 1W7XL 1EAIC 4NG9L 3HO5A 2H9EL 3HS6A 4JZEL 2OYUP 1M1XB 1I0UA 2BQ7A 4D90A 2P3TA 3R05A 2RA0L 4X8SL 3ELAL 1HAFA 3KQDL 1IOEL 1IQGL 2VVCK 2GD4A 1FAKL 1CX2A 5E8DA 2XBXL 1L5GB 3QCWA 5L2YL 3Q3KB 1XKBA 3LN1A 2P26A 5CKNA 2J38B 2YGOA 1CVWL 3NJPC 1ATDA 4JZFL 1F0RB 2PR3B 4D0FA 3BT2A 2BQ6A 2BZ6L 1EPHA 3LC5B 2YGPA 4ZXXL 2MGPA 1IQIL 4JZDL 2VH6B 5JW1A 3IJEB 3KCGL 3ZYGA 1LPKA 5I46L 4CSYA 1F7EA 5JB8E 1SZBA 1NFYB 4O1ZA 3RR3A 2JKHL 4LMFA 2PUQL 6COXA 1C5MF 4ISHL 3FFGL
chains in the Genus database with same CATH superfamily
3KQEL 1W8BL 1KLOA 4YZUB 2VRSA 3N8VA 2W86A 1LMMA 1QIUA 1FJSL 4X8TL 3BPSE 1CVUA 2K2SB 2XBVL 4OTJA 4BXWA 1FSBA 1CCVA 1ATBA 2WFTA 2BMGA 5F19A 2HOXA 2I9BA 4G1MB 4NGAL 2W2NE 1FAXL 2W3KB 1EQGA 3QH0A 1WHEA 2FLBL 2J34B 3SW2A 1N7DA 1DIYA 1G2MB 2K2TA 4CUDA 1EPGA 1OB1C 4ZH8B 3LC3B 3POYA 2UWOB 4X8VL 2FLGA 1ADXA 3TZIA 1GK5A 1YUKB 4A94C 4Y76B 5L30L 1FE2A 1CEJA 4CUFA 2UWLB 3HO4A 1G1QA 1PGEA 2VJ3A 5IKRA 1HREA 1YUGA 2OYEP 2W2QE 2Y7XB 4D0EA 3HPTA 4RRWA 4BTTA 1EPIA 4XBMA 5CISA 2P95L 3CS7L 4XLWA 1HZ8A 1APOA 3V65B 1P9JA 3GCXE 2H9EC 4O02B 5EGMB 2HORA 3OLUA 1KLIL 3LTFB 1HT5A 2P3FL 1QFKL 1XKAL 1X7AL 2ADXA 2B7DL 2XC5L 1G1TA 4Z0LA 4Y7BB 3NT1A 1YUFA 4BTUA 1NFXB 4XL1A 1XDTR 4Y7AB 2Y5HL 4YT6L 3FCSB 4MMYB 2MHPA 1Z6CA 2BT8A 3H5CB 3N8YB 1K36A 4RUTA 4CUEA 1PRHA 2VVUL 3KRKA 1DQBA 2NPRA 1LQDA 1HCGB 1UZJA 4RRXA 1IQFL 4E1GA 3F6UL 2W2ME 3N8WB 3CFWA 2XC0L 4ZAEB 4X8UL 3BT1A 2BQWA 3TK5B 3U7UG 2P3FN 5JVYA 2J4IB 4FM5A 1KIGL 5JBBE 2BO2A 1HAEA 1NZIA 4ZXYL 2KL7A 3K9XA 2D1JB 2WYGB 2WG4B 1LPGA 1IGZA 3HS7A 2FZZL 3DEMA 3KQBL 1IP0A 2WYJB 2VWLL 2WPIE 1IQHL 1U8CB 1TLEA 5IKQA 3TGFA 1U67A 2EI7B 4GU3A 1G2LB 2BOUA 1O5DL 1COUA 1UZQA 1Z6EL 5JB9E 4Z6AL 1K37A 3ASIA 4COXA 3LIWB 3TK6B 1V1HA 2BOKL 2PHBB 3KL6B 1LMJA 3SOQA 1JL9A 1NFUB 3Q7DA 1G1SA 3N8YA 3ZYJB 1P0SL 2P16L 2BT7A 2KB9A 4LORA 2WPLE 3MQEA 1CQEA 2WFXB 1KSNB 2I9AA 5JBCE 5COXA 3EGFA 3KK6A 2VWMK 2UWPB 3S6XA 3N8XA 3N8WA 2G00L 3LN0A 3NTGA 1DVAL 3TBDA 2VVVL 1YO8A 2P28B 1F7MA 3F1SB 1BF9A 1UZKA 3KQCL 3CA7A 1IVOC 1B9WA 1RFNB 5CKMA 1HRFA 1IQLL 4JYVL 3NTBA 1FFMA 1NPEB 1FF7A 1URKA 2RHPA 1DDXA 4JYUL 2Y5FL 5L2ZL 2XBYL 2WPKE 4BDWA 3ZYIB 1CCFA 1PTHA 2DDUA 5IKVA 4M11A 2P3UA 1J9CL 1EGFA 3SOVA 3OLTA 5K0HB 4BDXA 3TH3L 2F9BL 4RRZA 1EBVA 2EI6B 2TGFA 1NT0A 1LPZA 1MQ6L 2P93L 2Y7ZB 3QMOA 3SOBB 2Y5GL 1TOZA 2BOXA 2JJLA 1G1RA 2FLRL 1V1IA 3N8ZA 5IKTA 4Y71B 4YT7L 2EI8B 1HJ7A 2Y82B 1KLJL 4RS0A 2MGRA 1HX2A 1APQA 2BOHA 4Y79B 1YGCL 1ATAA 2WPME 4OTYA 2W3IB 1EPJA 1HT8A 1MQ5L 1PXXA 1EMNA 1NFWB 5JBAE 1PFXL 5FDQA 1F0SB 5KN5C 1DX5I 1TPGA 2WPHE 4ISIL 1IOXA 2W26B 3PGHA 2VWOL 4BTIA 1N1IA 4RRYA 5CKQA 3HS5A 3V64C 1EQHA 1MOXC 1A3PA 1KKEA 2WG3C 3HO3A 4MMXB 1ZAQA 4A7IA 3LTGD 1IGXA 2KNIA 3M37L 1EMOA 2FD6A 2VWNL 4M10A 3MDLA 1WHFA 3FBYA 2Y80B 1IQEL 4C16A 4PH9A 1IQJL 2Y38A 2AYLA 2P94L 4TGFA 1UZPA 2W2OE 3GISX 5KIRA 1WU1B 4BXSA 2M74A 2CJIB 5JVZA 1Q4GA 1V3XB 2Q1JB 4Z0KB 2XC4L 2XBWL 1IQML 4AQTA 2RNLA 1XFEA 5F1AA 1IJQA 2J2UB 1L3YA 4MMZB 2J95B 3ENSA 1NQLB 4ZHAB 2WPJE 2J94B 2KV4A 1JV2B 2W2PE 1JBUL 1ATEA 3C9AC 3U73A 1IQNL 3P5BL 1IQKL 3GCWE 4NA9L 4Y6DB 1AUTL 2Y81B 1EZQB 3M36L 3IITB 2VH0B 3CENL 3LAQA 1W7XL 1EAIC 4NG9L 3HO5A 2H9EL 3HS6A 4JZEL 2OYUP 1M1XB 1I0UA 2BQ7A 4D90A 2YGQA 2P3TA 3R05A 2RA0L 4X8SL 3ELAL 1HAFA 3KQDL 1IOEL 1IQGL 2VVCK 2WZPP 2GD4A 1FAKL 1CX2A 5E8DA 2XBXL 1L5GB 3QCWA 5L2YL 3Q3KB 1XKBA 3LN1A 2P26A 5CKNA 2J38B 2YGOA 1CVWL 3NJPC 1ATDA 4JZFL 1F0RB 4GU4A 2PR3B 4D0FA 3BT2A 2BQ6A 2BZ6L 2BSFA 1EPHA 3LC5B 2YGPA 4ZXXL 2MGPA 1IQIL 4JZDL 2VH6B 5JW1A 3IJEB 3KCGL 3ZYGA 1LPKA 5I46L 4CSYA 1F7EA 5JB8E 1SZBA 1NFYB 4O1ZA 3RR3A 1LK9A 2JKHL 4LMFA 2PUQL 6COXA 1C5MF 4ISHL 3FFGL
chains in the Genus database with same CATH topology
3KQEL 1W8BL 1KLOA 4YZUB 3N8VA 2W86A 1LMMA 1FJSL 4X8TL 3BPSE 1CVUA 2K2SB 2XBVL 4OTJA 4BXWA 1FSBA 1CCVA 1ATBA 2WFTA 2BMGA 5F19A 2I9BA 4G1MB 4NGAL 2W2NE 1FAXL 2W3KB 1EQGA 3QH0A 1WHEA 2FLBL 2J34B 3SW2A 1N7DA 1DIYA 1G2MB 2K2TA 4CUDA 1EPGA 1OB1C 4ZH8B 3LC3B 3POYA 2UWOB 4X8VL 2FLGA 1ADXA 3TZIA 1GK5A 1YUKB 4A94C 4Y76B 5L30L 1FE2A 1CEJA 4CUFA 2UWLB 3HO4A 1G1QA 1PGEA 2VJ3A 5IKRA 1HREA 1YUGA 2OYEP 2W2QE 2Y7XB 4D0EA 3HPTA 4RRWA 4BTTA 1EPIA 4XBMA 5CISA 2P95L 3CS7L 4XLWA 1HZ8A 1APOA 3V65B 1P9JA 3GCXE 2H9EC 4O02B 5EGMB 3OLUA 1KLIL 3LTFB 1HT5A 2P3FL 1QFKL 1XKAL 1X7AL 2ADXA 2B7DL 2XC5L 1G1TA 4Z0LA 4Y7BB 3NT1A 1YUFA 4BTUA 1NFXB 4XL1A 1XDTR 4Y7AB 2Y5HL 4YT6L 3FCSB 4MMYB 2MHPA 1Z6CA 3H5CB 3N8YB 1K36A 4RUTA 4CUEA 1PRHA 2VVUL 3KRKA 1DQBA 2NPRA 1LQDA 1HCGB 1UZJA 4RRXA 1IQFL 4E1GA 3F6UL 2W2ME 3N8WB 3CFWA 2XC0L 4ZAEB 4X8UL 3BT1A 2BQWA 3TK5B 3U7UG 2P3FN 5JVYA 2J4IB 4FM5A 1KIGL 5JBBE 2BO2A 1HAEA 1NZIA 4ZXYL 2KL7A 3K9XA 2D1JB 2WYGB 2WG4B 1LPGA 1IGZA 3HS7A 2FZZL 3DEMA 3KQBL 1IP0A 2WYJB 2VWLL 2WPIE 1IQHL 1U8CB 1TLEA 5IKQA 3TGFA 1U67A 2EI7B 1G2LB 2BOUA 1O5DL 1COUA 1UZQA 1Z6EL 5JB9E 4Z6AL 1K37A 3ASIA 4COXA 3LIWB 3TK6B 2BOKL 2PHBB 3KL6B 1LMJA 3SOQA 1JL9A 1NFUB 3Q7DA 1G1SA 3N8YA 3ZYJB 1P0SL 2P16L 2KB9A 4LORA 2WPLE 3MQEA 1CQEA 2WFXB 1KSNB 2I9AA 5JBCE 5COXA 3EGFA 3KK6A 2VWMK 2UWPB 3S6XA 3N8XA 3N8WA 2G00L 3LN0A 3NTGA 1DVAL 3TBDA 2VVVL 1YO8A 2P28B 1F7MA 3F1SB 1BF9A 1UZKA 3KQCL 3CA7A 1IVOC 1B9WA 1RFNB 5CKMA 1HRFA 1IQLL 4JYVL 3NTBA 1FFMA 1NPEB 1FF7A 1URKA 2RHPA 1DDXA 4JYUL 2Y5FL 5L2ZL 2XBYL 2WPKE 4BDWA 3ZYIB 1CCFA 1PTHA 2DDUA 5IKVA 4M11A 2P3UA 1J9CL 1EGFA 3SOVA 3OLTA 5K0HB 4BDXA 3TH3L 2F9BL 4RRZA 1EBVA 2EI6B 2TGFA 1NT0A 1LPZA 1MQ6L 2P93L 2Y7ZB 3QMOA 3SOBB 2Y5GL 1TOZA 2BOXA 1G1RA 2FLRL 3N8ZA 5IKTA 4Y71B 4YT7L 2EI8B 1HJ7A 2Y82B 1KLJL 4RS0A 2MGRA 1HX2A 1APQA 2BOHA 4Y79B 1YGCL 1ATAA 2WPME 4OTYA 2W3IB 1EPJA 1HT8A 1MQ5L 1PXXA 1EMNA 1NFWB 5JBAE 1PFXL 5FDQA 1F0SB 5KN5C 1DX5I 1TPGA 2WPHE 4ISIL 1IOXA 2W26B 3PGHA 2VWOL 4BTIA 1N1IA 4RRYA 5CKQA 3HS5A 3V64C 1EQHA 1MOXC 1A3PA 4MMXB 2WG3C 3HO3A 1ZAQA 4A7IA 3LTGD 1IGXA 2KNIA 3M37L 1EMOA 2FD6A 2VWNL 4M10A 3MDLA 1WHFA 3FBYA 2Y80B 1IQEL 4C16A 4PH9A 1IQJL 2Y38A 2AYLA 2P94L 4TGFA 1UZPA 2W2OE 3GISX 5KIRA 1WU1B 4BXSA 2M74A 2CJIB 5JVZA 1Q4GA 1V3XB 2Q1JB 4Z0KB 2XC4L 2XBWL 1IQML 4AQTA 2RNLA 1XFEA 5F1AA 1IJQA 2J2UB 1L3YA 4MMZB 2J95B 3ENSA 1NQLB 4ZHAB 2WPJE 2J94B 2KV4A 1JV2B 2W2PE 1JBUL 1ATEA 3C9AC 3U73A 1IQNL 3P5BL 1IQKL 3GCWE 4NA9L 4Y6DB 1AUTL 2Y81B 1EZQB 3M36L 3IITB 2VH0B 3CENL 3LAQA 1W7XL 1EAIC 4NG9L 3HO5A 2H9EL 3HS6A 4JZEL 2OYUP 1M1XB 1I0UA 2BQ7A 4D90A 2YGQA 2P3TA 3R05A 2RA0L 4X8SL 3ELAL 1HAFA 3KQDL 1IOEL 1IQGL 2VVCK 2WZPP 2GD4A 1FAKL 1CX2A 5E8DA 2XBXL 1L5GB 3QCWA 5L2YL 3Q3KB 1XKBA 3LN1A 2P26A 5CKNA 2J38B 2YGOA 1CVWL 3NJPC 1ATDA 4JZFL 1F0RB 2PR3B 4D0FA 3BT2A 2BQ6A 2BZ6L 1EPHA 3LC5B 2YGPA 4ZXXL 2MGPA 1IQIL 4JZDL 2VH6B 5JW1A 3IJEB 3KCGL 3ZYGA 1LPKA 5I46L 4CSYA 1F7EA 5JB8E 1SZBA 1NFYB 4O1ZA 3RR3A 2JKHL 4LMFA 2PUQL 6COXA 1C5MF 4ISHL 3FFGL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KQE L;  1W8B L;  1KLO A;  4YZU B;  3N8V A;  2W86 A;  1FJS L;  4X8T L;  3BPS E;  1CVU A;  2K2S B;  2XBV L;  4OTJ A;  4BXW A;  1FSB A;  1CCV A;  1ATB A;  2WFT A;  2BMG A;  5F19 A;  2I9B A;  4G1M B;  4NGA L;  2W2N E;  1FAX L;  2W3K B;  1EQG A;  3QH0 A;  1WHE A;  2FLB L;  2J34 B;  3SW2 A;  1N7D A;  1DIY A;  1G2M B;  2K2T A;  4CUD A;  1EPG A;  1OB1 C;  4ZH8 B;  3LC3 B;  3POY A;  2UWO B;  4X8V L;  2FLG A;  1ADX A;  3TZI A;  1GK5 A;  1YUK B;  5L30 L;  4Y76 B;  1FE2 A;  1CEJ A;  4CUF A;  2UWL B;  3HO4 A;  1G1Q A;  1PGE A;  2VJ3 A;  5IKR A;  1HRE A;  1YUG A;  2OYE P;  2W2Q E;  2Y7X B;  4D0E A;  3HPT A;  4RRW A;  4BTT A;  1EPI A;  4XBM A;  5CIS A;  2P95 L;  3CS7 L;  4XLW A;  1HZ8 A;  1APO A;  3V65 B;  1P9J A;  3GCX E;  4O02 B;  5EGM B;  3OLU A;  1KLI L;  3LTF B;  1HT5 A;  2P3F L;  1QFK L;  1XKA L;  1X7A L;  2ADX A;  2B7D L;  2XC5 L;  1G1T A;  4Z0L A;  4Y7B B;  3NT1 A;  1YUF A;  4BTU A;  1NFX B;  4XL1 A;  1XDT R;  4Y7A B;  2Y5H L;  4YT6 L;  3FCS B;  4MMY B;  2MHP A;  1Z6C A;  3H5C B;  3N8Y B;  1K36 A;  4RUT A;  4CUE A;  1PRH A;  2VVU L;  3KRK A;  1DQB A;  2NPR A;  1LQD A;  1HCG B;  1UZJ A;  4RRX A;  1IQF L;  4E1G A;  3F6U L;  2W2M E;  3N8W B;  3CFW A;  2XC0 L;  4ZAE B;  4X8U L;  3BT1 A;  2BQW A;  3TK5 B;  3U7U G;  2P3F N;  5JVY A;  2J4I B;  4FM5 A;  1KIG L;  5JBB E;  2BO2 A;  1HAE A;  1NZI A;  4ZXY L;  2KL7 A;  3K9X A;  2D1J B;  2WYG B;  2WG4 B;  1LPG A;  1IGZ A;  3HS7 A;  2FZZ L;  3DEM A;  3KQB L;  1IP0 A;  2WYJ B;  2VWL L;  2WPI E;  1IQH L;  1U8C B;  1TLE A;  5IKQ A;  3TGF A;  1U67 A;  2EI7 B;  1G2L B;  2BOU A;  1O5D L;  1COU A;  1UZQ A;  1Z6E L;  5JB9 E;  4Z6A L;  1K37 A;  3ASI A;  4COX A;  3LIW B;  3TK6 B;  2BOK L;  2PHB B;  3KL6 B;  1LMJ A;  3SOQ A;  1JL9 A;  1NFU B;  3Q7D A;  1G1S A;  3N8Y A;  3ZYJ B;  1P0S L;  2P16 L;  2KB9 A;  4LOR A;  2WPL E;  3MQE A;  1CQE A;  2WFX B;  1KSN B;  2I9A A;  5JBC E;  5COX A;  3EGF A;  3KK6 A;  2VWM K;  2UWP B;  3N8X A;  3N8W A;  2G00 L;  3LN0 A;  3NTG A;  1DVA L;  3TBD A;  2VVV L;  1YO8 A;  2P28 B;  1F7M A;  3F1S B;  1BF9 A;  1UZK A;  3KQC L;  3CA7 A;  1IVO C;  1B9W A;  1RFN B;  5CKM A;  1HRF A;  1IQL L;  4JYV L;  3NTB A;  1FFM A;  1NPE B;  1FF7 A;  1URK A;  2RHP A;  1DDX A;  4JYU L;  2Y5F L;  5L2Z L;  2XBY L;  2WPK E;  4BDW A;  3ZYI B;  1CCF A;  1PTH A;  2DDU A;  5IKV A;  4M11 A;  2P3U A;  1J9C L;  1EGF A;  3SOV A;  3OLT A;  5K0H B;  4BDX A;  3TH3 L;  2F9B L;  4RRZ A;  1EBV A;  2EI6 B;  2TGF A;  1NT0 A;  1LPZ A;  1MQ6 L;  2P93 L;  2Y7Z B;  3QMO A;  3SOB B;  2Y5G L;  1TOZ A;  2BOX A;  1G1R A;  2FLR L;  3N8Z A;  5IKT A;  4Y71 B;  4YT7 L;  2EI8 B;  1HJ7 A;  2Y82 B;  1KLJ L;  4RS0 A;  2MGR A;  1HX2 A;  1APQ A;  2BOH A;  4Y79 B;  1YGC L;  1ATA A;  2WPM E;  4OTY A;  2W3I B;  1EPJ A;  1HT8 A;  1MQ5 L;  1PXX A;  1EMN A;  1NFW B;  5JBA E;  1PFX L;  5FDQ A;  1F0S B;  5KN5 C;  1DX5 I;  1TPG A;  2WPH E;  4ISI L;  1IOX A;  2W26 B;  3PGH A;  2VWO L;  4BTI A;  1N1I A;  4RRY A;  5CKQ A;  3HS5 A;  3V64 C;  1EQH A;  1MOX C;  1A3P A;  4MMX B;  2WG3 C;  3HO3 A;  1ZAQ A;  4A7I A;  3LTG D;  1IGX A;  3M37 L;  1EMO A;  2FD6 A;  2VWN L;  4M10 A;  3MDL A;  1WHF A;  3FBY A;  2Y80 B;  1IQE L;  4C16 A;  4PH9 A;  1IQJ L;  2Y38 A;  2AYL A;  2P94 L;  4TGF A;  1UZP A;  2W2O E;  3GIS X;  5KIR A;  1WU1 B;  4BXS A;  2M74 A;  2CJI B;  5JVZ A;  1Q4G A;  1V3X B;  2Q1J B;  4Z0K B;  2XC4 L;  2XBW L;  1IQM L;  4AQT A;  2RNL A;  1XFE A;  5F1A A;  1IJQ A;  2J2U B;  1L3Y A;  4MMZ B;  2J95 B;  3ENS A;  1NQL B;  4ZHA B;  2WPJ E;  2J94 B;  2KV4 A;  1JV2 B;  2W2P E;  1JBU L;  1ATE A;  3C9A C;  3U73 A;  1IQN L;  3P5B L;  1IQK L;  3GCW E;  4NA9 L;  4Y6D B;  1AUT L;  2Y81 B;  1EZQ B;  3M36 L;  3IIT B;  2VH0 B;  3CEN L;  3LAQ A;  1W7X L;  1EAI C;  4NG9 L;  3HO5 A;  2H9E L;  3HS6 A;  4JZE L;  2OYU P;  1M1X B;  1I0U A;  2BQ7 A;  4D90 A;  2P3T A;  3R05 A;  2RA0 L;  4X8S L;  3ELA L;  1HAF A;  3KQD L;  1IOE L;  1IQG L;  2VVC K;  2GD4 A;  1FAK L;  1CX2 A;  5E8D A;  2XBX L;  1L5G B;  3QCW A;  5L2Y L;  3Q3K B;  1XKB A;  3LN1 A;  2P26 A;  5CKN A;  2J38 B;  2YGO A;  1CVW L;  3NJP C;  1ATD A;  4JZF L;  1F0R B;  2PR3 B;  4D0F A;  3BT2 A;  2BQ6 A;  2BZ6 L;  1EPH A;  3LC5 B;  2YGP A;  4ZXX L;  2MGP A;  1IQI L;  4JZD L;  2VH6 B;  5JW1 A;  3IJE B;  3KCG L;  3ZYG A;  1LPK A;  5I46 L;  4CSY A;  1F7E A;  5JB8 E;  1SZB A;  1NFY B;  4O1Z A;  3RR3 A;  2JKH L;  4LMF A;  2PUQ L;  6COX A;  1C5M F;  4ISH L;  3FFG L; 
#chains in the Genus database with same CATH topology
 3KQE L;  1W8B L;  1KLO A;  4YZU B;  2VRS A;  3N8V A;  2W86 A;  1LMM A;  1QIU A;  1FJS L;  4X8T L;  3BPS E;  1CVU A;  2K2S B;  2XBV L;  4OTJ A;  4BXW A;  1FSB A;  1CCV A;  1ATB A;  2WFT A;  2BMG A;  5F19 A;  2HOX A;  2I9B A;  4G1M B;  4NGA L;  2W2N E;  1FAX L;  2W3K B;  1EQG A;  3QH0 A;  1WHE A;  2FLB L;  2J34 B;  3SW2 A;  1N7D A;  1DIY A;  1G2M B;  2K2T A;  4CUD A;  1EPG A;  1OB1 C;  4ZH8 B;  3LC3 B;  3POY A;  2UWO B;  4X8V L;  2FLG A;  1ADX A;  3TZI A;  1GK5 A;  1YUK B;  4A94 C;  4Y76 B;  5L30 L;  1FE2 A;  1CEJ A;  4CUF A;  2UWL B;  3HO4 A;  1G1Q A;  1PGE A;  2VJ3 A;  5IKR A;  1HRE A;  1YUG A;  2OYE P;  2W2Q E;  2Y7X B;  4D0E A;  3HPT A;  4RRW A;  4BTT A;  1EPI A;  4XBM A;  5CIS A;  2P95 L;  3CS7 L;  4XLW A;  1HZ8 A;  1APO A;  3V65 B;  1P9J A;  3GCX E;  2H9E C;  4O02 B;  5EGM B;  2HOR A;  3OLU A;  1KLI L;  3LTF B;  1HT5 A;  2P3F L;  1QFK L;  1XKA L;  1X7A L;  2ADX A;  2B7D L;  2XC5 L;  1G1T A;  4Z0L A;  4Y7B B;  3NT1 A;  1YUF A;  4BTU A;  1NFX B;  4XL1 A;  1XDT R;  4Y7A B;  2Y5H L;  4YT6 L;  3FCS B;  4MMY B;  2MHP A;  1Z6C A;  2BT8 A;  3H5C B;  3N8Y B;  1K36 A;  4RUT A;  4CUE A;  1PRH A;  2VVU L;  3KRK A;  1DQB A;  2NPR A;  1LQD A;  1HCG B;  1UZJ A;  4RRX A;  1IQF L;  4E1G A;  3F6U L;  2W2M E;  3N8W B;  3CFW A;  2XC0 L;  4ZAE B;  4X8U L;  3BT1 A;  2BQW A;  3TK5 B;  3U7U G;  2P3F N;  5JVY A;  2J4I B;  4FM5 A;  1KIG L;  5JBB E;  2BO2 A;  1HAE A;  1NZI A;  4ZXY L;  2KL7 A;  3K9X A;  2D1J B;  2WYG B;  2WG4 B;  1LPG A;  1IGZ A;  3HS7 A;  2FZZ L;  3DEM A;  3KQB L;  1IP0 A;  2WYJ B;  2VWL L;  2WPI E;  1IQH L;  1U8C B;  1TLE A;  5IKQ A;  3TGF A;  1U67 A;  2EI7 B;  4GU3 A;  1G2L B;  2BOU A;  1O5D L;  1COU A;  1UZQ A;  1Z6E L;  5JB9 E;  4Z6A L;  1K37 A;  3ASI A;  4COX A;  3LIW B;  3TK6 B;  1V1H A;  2BOK L;  2PHB B;  3KL6 B;  1LMJ A;  3SOQ A;  1JL9 A;  1NFU B;  3Q7D A;  1G1S A;  3N8Y A;  3ZYJ B;  1P0S L;  2P16 L;  2BT7 A;  2KB9 A;  4LOR A;  2WPL E;  3MQE A;  1CQE A;  2WFX B;  1KSN B;  2I9A A;  5JBC E;  5COX A;  3EGF A;  3KK6 A;  2VWM K;  2UWP B;  3S6X A;  3N8X A;  3N8W A;  2G00 L;  3LN0 A;  3NTG A;  1DVA L;  3TBD A;  2VVV L;  1YO8 A;  2P28 B;  1F7M A;  3F1S B;  1BF9 A;  1UZK A;  3KQC L;  3CA7 A;  1IVO C;  1B9W A;  1RFN B;  5CKM A;  1HRF A;  1IQL L;  4JYV L;  3NTB A;  1FFM A;  1NPE B;  1FF7 A;  1URK A;  2RHP A;  1DDX A;  4JYU L;  2Y5F L;  5L2Z L;  2XBY L;  2WPK E;  4BDW A;  3ZYI B;  1CCF A;  1PTH A;  2DDU A;  5IKV A;  4M11 A;  2P3U A;  1J9C L;  1EGF A;  3SOV A;  3OLT A;  5K0H B;  4BDX A;  3TH3 L;  2F9B L;  4RRZ A;  1EBV A;  2EI6 B;  2TGF A;  1NT0 A;  1LPZ A;  1MQ6 L;  2P93 L;  2Y7Z B;  3QMO A;  3SOB B;  2Y5G L;  1TOZ A;  2BOX A;  2JJL A;  1G1R A;  2FLR L;  1V1I A;  3N8Z A;  5IKT A;  4Y71 B;  4YT7 L;  2EI8 B;  1HJ7 A;  2Y82 B;  1KLJ L;  4RS0 A;  2MGR A;  1HX2 A;  1APQ A;  2BOH A;  4Y79 B;  1YGC L;  1ATA A;  2WPM E;  4OTY A;  2W3I B;  1EPJ A;  1HT8 A;  1MQ5 L;  1PXX A;  1EMN A;  1NFW B;  5JBA E;  1PFX L;  5FDQ A;  1F0S B;  5KN5 C;  1DX5 I;  1TPG A;  2WPH E;  4ISI L;  1IOX A;  2W26 B;  3PGH A;  2VWO L;  4BTI A;  1N1I A;  4RRY A;  5CKQ A;  3HS5 A;  3V64 C;  1EQH A;  1MOX C;  1A3P A;  1KKE A;  2WG3 C;  3HO3 A;  4MMX B;  1ZAQ A;  4A7I A;  3LTG D;  1IGX A;  2KNI A;  3M37 L;  1EMO A;  2FD6 A;  2VWN L;  4M10 A;  3MDL A;  1WHF A;  3FBY A;  2Y80 B;  1IQE L;  4C16 A;  4PH9 A;  1IQJ L;  2Y38 A;  2AYL A;  2P94 L;  4TGF A;  1UZP A;  2W2O E;  3GIS X;  5KIR A;  1WU1 B;  4BXS A;  2M74 A;  2CJI B;  5JVZ A;  1Q4G A;  1V3X B;  2Q1J B;  4Z0K B;  2XC4 L;  2XBW L;  1IQM L;  4AQT A;  2RNL A;  1XFE A;  5F1A A;  1IJQ A;  2J2U B;  1L3Y A;  4MMZ B;  2J95 B;  3ENS A;  1NQL B;  4ZHA B;  2WPJ E;  2J94 B;  2KV4 A;  1JV2 B;  2W2P E;  1JBU L;  1ATE A;  3C9A C;  3U73 A;  1IQN L;  3P5B L;  1IQK L;  3GCW E;  4NA9 L;  4Y6D B;  1AUT L;  2Y81 B;  1EZQ B;  3M36 L;  3IIT B;  2VH0 B;  3CEN L;  3LAQ A;  1W7X L;  1EAI C;  4NG9 L;  3HO5 A;  2H9E L;  3HS6 A;  4JZE L;  2OYU P;  1M1X B;  1I0U A;  2BQ7 A;  4D90 A;  2YGQ A;  2P3T A;  3R05 A;  2RA0 L;  4X8S L;  3ELA L;  1HAF A;  3KQD L;  1IOE L;  1IQG L;  2VVC K;  2WZP P;  2GD4 A;  1FAK L;  1CX2 A;  5E8D A;  2XBX L;  1L5G B;  3QCW A;  5L2Y L;  3Q3K B;  1XKB A;  3LN1 A;  2P26 A;  5CKN A;  2J38 B;  2YGO A;  1CVW L;  3NJP C;  1ATD A;  4JZF L;  1F0R B;  4GU4 A;  2PR3 B;  4D0F A;  3BT2 A;  2BQ6 A;  2BZ6 L;  2BSF A;  1EPH A;  3LC5 B;  2YGP A;  4ZXX L;  2MGP A;  1IQI L;  4JZD L;  2VH6 B;  5JW1 A;  3IJE B;  3KCG L;  3ZYG A;  1LPK A;  5I46 L;  4CSY A;  1F7E A;  5JB8 E;  1SZB A;  1NFY B;  4O1Z A;  3RR3 A;  1LK9 A;  2JKH L;  4LMF A;  2PUQ L;  6COX A;  1C5M F;  4ISH L;  3FFG L; 
#chains in the Genus database with same CATH homology
 3KQE L;  1W8B L;  1KLO A;  4YZU B;  3N8V A;  2W86 A;  1LMM A;  1FJS L;  4X8T L;  3BPS E;  1CVU A;  2K2S B;  2XBV L;  4OTJ A;  4BXW A;  1FSB A;  1CCV A;  1ATB A;  2WFT A;  2BMG A;  5F19 A;  2I9B A;  4G1M B;  4NGA L;  2W2N E;  1FAX L;  2W3K B;  1EQG A;  3QH0 A;  1WHE A;  2FLB L;  2J34 B;  3SW2 A;  1N7D A;  1DIY A;  1G2M B;  2K2T A;  4CUD A;  1EPG A;  1OB1 C;  4ZH8 B;  3LC3 B;  3POY A;  2UWO B;  4X8V L;  2FLG A;  1ADX A;  3TZI A;  1GK5 A;  1YUK B;  4A94 C;  4Y76 B;  5L30 L;  1FE2 A;  1CEJ A;  4CUF A;  2UWL B;  3HO4 A;  1G1Q A;  1PGE A;  2VJ3 A;  5IKR A;  1HRE A;  1YUG A;  2OYE P;  2W2Q E;  2Y7X B;  4D0E A;  3HPT A;  4RRW A;  4BTT A;  1EPI A;  4XBM A;  5CIS A;  2P95 L;  3CS7 L;  4XLW A;  1HZ8 A;  1APO A;  3V65 B;  1P9J A;  3GCX E;  2H9E C;  4O02 B;  5EGM B;  3OLU A;  1KLI L;  3LTF B;  1HT5 A;  2P3F L;  1QFK L;  1XKA L;  1X7A L;  2ADX A;  2B7D L;  2XC5 L;  1G1T A;  4Z0L A;  4Y7B B;  3NT1 A;  1YUF A;  4BTU A;  1NFX B;  4XL1 A;  1XDT R;  4Y7A B;  2Y5H L;  4YT6 L;  3FCS B;  4MMY B;  2MHP A;  1Z6C A;  3H5C B;  3N8Y B;  1K36 A;  4RUT A;  4CUE A;  1PRH A;  2VVU L;  3KRK A;  1DQB A;  2NPR A;  1LQD A;  1HCG B;  1UZJ A;  4RRX A;  1IQF L;  4E1G A;  3F6U L;  2W2M E;  3N8W B;  3CFW A;  2XC0 L;  4ZAE B;  4X8U L;  3BT1 A;  2BQW A;  3TK5 B;  3U7U G;  2P3F N;  5JVY A;  2J4I B;  4FM5 A;  1KIG L;  5JBB E;  2BO2 A;  1HAE A;  1NZI A;  4ZXY L;  2KL7 A;  3K9X A;  2D1J B;  2WYG B;  2WG4 B;  1LPG A;  1IGZ A;  3HS7 A;  2FZZ L;  3DEM A;  3KQB L;  1IP0 A;  2WYJ B;  2VWL L;  2WPI E;  1IQH L;  1U8C B;  1TLE A;  5IKQ A;  3TGF A;  1U67 A;  2EI7 B;  1G2L B;  2BOU A;  1O5D L;  1COU A;  1UZQ A;  1Z6E L;  5JB9 E;  4Z6A L;  1K37 A;  3ASI A;  4COX A;  3LIW B;  3TK6 B;  2BOK L;  2PHB B;  3KL6 B;  1LMJ A;  3SOQ A;  1JL9 A;  1NFU B;  3Q7D A;  1G1S A;  3N8Y A;  3ZYJ B;  1P0S L;  2P16 L;  2KB9 A;  4LOR A;  2WPL E;  3MQE A;  1CQE A;  2WFX B;  1KSN B;  2I9A A;  5JBC E;  5COX A;  3EGF A;  3KK6 A;  2VWM K;  2UWP B;  3S6X A;  3N8X A;  3N8W A;  2G00 L;  3LN0 A;  3NTG A;  1DVA L;  3TBD A;  2VVV L;  1YO8 A;  2P28 B;  1F7M A;  3F1S B;  1BF9 A;  1UZK A;  3KQC L;  3CA7 A;  1IVO C;  1B9W A;  1RFN B;  5CKM A;  1HRF A;  1IQL L;  4JYV L;  3NTB A;  1FFM A;  1NPE B;  1FF7 A;  1URK A;  2RHP A;  1DDX A;  4JYU L;  2Y5F L;  5L2Z L;  2XBY L;  2WPK E;  4BDW A;  3ZYI B;  1CCF A;  1PTH A;  2DDU A;  5IKV A;  4M11 A;  2P3U A;  1J9C L;  1EGF A;  3SOV A;  3OLT A;  5K0H B;  4BDX A;  3TH3 L;  2F9B L;  4RRZ A;  1EBV A;  2EI6 B;  2TGF A;  1NT0 A;  1LPZ A;  1MQ6 L;  2P93 L;  2Y7Z B;  3QMO A;  3SOB B;  2Y5G L;  1TOZ A;  2BOX A;  1G1R A;  2FLR L;  3N8Z A;  5IKT A;  4Y71 B;  4YT7 L;  2EI8 B;  1HJ7 A;  2Y82 B;  1KLJ L;  4RS0 A;  2MGR A;  1HX2 A;  1APQ A;  2BOH A;  4Y79 B;  1YGC L;  1ATA A;  2WPM E;  4OTY A;  2W3I B;  1EPJ A;  1HT8 A;  1MQ5 L;  1PXX A;  1EMN A;  1NFW B;  5JBA E;  1PFX L;  5FDQ A;  1F0S B;  5KN5 C;  1DX5 I;  1TPG A;  2WPH E;  4ISI L;  1IOX A;  2W26 B;  3PGH A;  2VWO L;  4BTI A;  1N1I A;  4RRY A;  5CKQ A;  3HS5 A;  3V64 C;  1EQH A;  1MOX C;  1A3P A;  4MMX B;  2WG3 C;  3HO3 A;  1ZAQ A;  4A7I A;  3LTG D;  1IGX A;  2KNI A;  3M37 L;  1EMO A;  2FD6 A;  2VWN L;  4M10 A;  3MDL A;  1WHF A;  3FBY A;  2Y80 B;  1IQE L;  4C16 A;  4PH9 A;  1IQJ L;  2Y38 A;  2AYL A;  2P94 L;  4TGF A;  1UZP A;  2W2O E;  3GIS X;  5KIR A;  1WU1 B;  4BXS A;  2M74 A;  2CJI B;  5JVZ A;  1Q4G A;  1V3X B;  2Q1J B;  4Z0K B;  2XC4 L;  2XBW L;  1IQM L;  4AQT A;  2RNL A;  1XFE A;  5F1A A;  1IJQ A;  2J2U B;  1L3Y A;  4MMZ B;  2J95 B;  3ENS A;  1NQL B;  4ZHA B;  2WPJ E;  2J94 B;  2KV4 A;  1JV2 B;  2W2P E;  1JBU L;  1ATE A;  3C9A C;  3U73 A;  1IQN L;  3P5B L;  1IQK L;  3GCW E;  4NA9 L;  4Y6D B;  1AUT L;  2Y81 B;  1EZQ B;  3M36 L;  3IIT B;  2VH0 B;  3CEN L;  3LAQ A;  1W7X L;  1EAI C;  4NG9 L;  3HO5 A;  2H9E L;  3HS6 A;  4JZE L;  2OYU P;  1M1X B;  1I0U A;  2BQ7 A;  4D90 A;  2YGQ A;  2P3T A;  3R05 A;  2RA0 L;  4X8S L;  3ELA L;  1HAF A;  3KQD L;  1IOE L;  1IQG L;  2VVC K;  2WZP P;  2GD4 A;  1FAK L;  1CX2 A;  5E8D A;  2XBX L;  1L5G B;  3QCW A;  5L2Y L;  3Q3K B;  1XKB A;  3LN1 A;  2P26 A;  5CKN A;  2J38 B;  2YGO A;  1CVW L;  3NJP C;  1ATD A;  4JZF L;  1F0R B;  2PR3 B;  4D0F A;  3BT2 A;  2BQ6 A;  2BZ6 L;  1EPH A;  3LC5 B;  2YGP A;  4ZXX L;  2MGP A;  1IQI L;  4JZD L;  2VH6 B;  5JW1 A;  3IJE B;  3KCG L;  3ZYG A;  1LPK A;  5I46 L;  4CSY A;  1F7E A;  5JB8 E;  1SZB A;  1NFY B;  4O1Z A;  3RR3 A;  2JKH L;  4LMF A;  2PUQ L;  6COX A;  1C5M F;  4ISH L;  3FFG L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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