2XBVL

Factor xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
50
structure length
43
Chain Sequence
CSDNGDCDQFCVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a Factor Xa Inhibitor (3R,4R)-1-(2,2-Difluoro-Ethyl)-Pyrrolidine-3,4-Dicarboxylic Acid 3-[(5-Chloro-Pyridin-2-Yl)-Amide] 4-{[2-Fluoro-4-(2-Oxo-2H-Pyridin-1-Yl)-Phenyl]-Amide} as a Clinical Candidate.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 7
structure length 43
sequence length 50
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2010-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2xbvL00
2P95L 2WPJE 1LQDA 4RRXA 3NTGA 2WPLE 1IQML 3TK6B 2Y82B 3ENSA 3HS5A 4BDWA 1IGZA 2W2NE 1NFUB 4D90A 2Q1JB 2Y5HL 2FLGA 3SOVA 3DEMA 4BXSA 3KK6A 5F1AA 4X8SL 2FLBL 1EAIC 1XDTR 1TPGA 5JBBE 1EPHA 4A7IA 2AYLA 1IQIL 2BQ6A 4PH9A 1EPJA 1Z6CA 2W86A 3N8VA 2WG3C 5L2ZL 1UZPA 1UZJA 1HREA 2KV4A 1MOXC 2VH6B 2PUQL 3EGFA 4XBMA 3F1SB 1YUGA 1P9JA 2PR3B 1F7EA 3M36L 1L3YA 3KQBL 2P94L 3H5CB 2WPME 2K2TA 2WFXB 3LN0A 2XC4L 1PGEA 1HT8A 1EQGA 3Q3KB 2Y81B 1G1QA 3GISX 5JBCE 2W3KB 1HAEA 4MMYB 4RRZA 1KLOA 2K2SB 2UWOB 3PGHA 4G1MB 3N8WA 1XFEA 2BOKL 4Y7BB 1FAKL 3M37L 3N8WB 1IVOC 2M74A 2XC0L 4TGFA 4BTUA 1O5DL 3OLUA 2W2OE 2BMGA 1W8BL 1L5GB 1U8CB 1HCGB 2J95B 4JYUL 3K9XA 1YUKB 2WPIE 4D0EA 1JV2B 1K37A 4X8VL 1F0RB 1Q4GA 3ZYJB 4Y7AB 5E8DA 1ZAQA 1COUA 2P3FL 5I46L 5IKVA 1EBVA 1F7MA 3V64C 2WYGB 3HPTA 3KL6B 1CX2A 3MDLA 3ZYIB 1PXXA 3BPSE 3TGFA 2I9BA 4M10A 1HZ8A 1DIYA 1C5MF 4E1GA 4RS0A 2DDUA 1Z6EL 2XBYL 1ATEA 1J9CL 3MQEA 4MMXB 1A3PA 1MQ5L 3KQDL 3V65B 2MGRA 3KQEL 4NG9L 1CCFA 2RHPA 3POYA 2ADXA 4AQTA 4ISHL 4XL1A 2W2PE 2Y7ZB 1KSNB 1KIGL 4YZUB 1EQHA 2BOHA 3GCXE 3HS6A 3Q7DA 1SZBA 3KQCL 4CUFA 2W2QE 4Y79B 2BQWA 4YT6L 1HT5A 2FZZL 4MMZB 2F9BL 5CKNA 1YO8A 5JW1A 1IQFL 1N7DA 1NFYB 5KN5C 1G1RA 1HRFA 1YUFA 2PHBB 4M11A 3NJPC 2WPHE 1MQ6L 1JBUL 3CENL 2XBXL 1FFMA 3U73A 1EZQB 1F0SB 1W7XL 1QFKL 2UWPB 3LN1A 3ELAL 1HAFA 2EI8B 2J94B 1URKA 4X8TL 1APOA 3HO4A 2XBWL 1OB1C 4CUEA 4ZAEB 4NA9L 1LMJA 3F6UL 1IP0A 1IOEL 1KLJL 2P3FN 3CFWA 1LPZA 3CA7A 5L30L 4COXA 3FCSB 1PRHA 2Y7XB 3N8XA 3RR3A 4O1ZA 4X8UL 2EI6B 2VJ3A 1V3XB 2Y5FL 1IQJL 5K0HB 3QCWA 1TOZA 3NTBA 2VVCK 2P3TA 2EI7B 4BTTA 2J34B 3LIWB 2I9AA 2GD4A 1CVWL 1G1TA 2D1JB 3C9AC 4Y76B 2BZ6L 1DX5I 1NPEB 3TH3L 4Z0LA 5COXA 1EPGA 1EMOA 4Y71B 5CKQA 1PTHA 2WPKE 1ATAA 1WU1B 1IQLL 1PFXL 2J2UB 3LAQA 2OYUP 3LC3B 2Y80B 2NPRA 5JVYA 5JB9E 4Y6DB 1EMNA 1NFWB 3FFGL 3LTFB 3LTGD 3LC5B 1K36A 2VH0B 5EGMB 3SOQA 1CQEA 1FJSL 3KRKA 2MGPA 1XKAL 1YGCL 1UZKA 4O02B 3N8YA 2P16L 4BDXA 1I0UA 3ASIA 1JL9A 1IGXA 1G1SA 2JKHL 4ZH8B 3N8YB 1B9WA 1ATBA 2YGOA 1HX2A 1XKBA 3QH0A 2WFTA 2VWNL 1LPKA 6COXA 4RRWA 5FDQA 4ZHAB 3OLTA 3TZIA 5IKQA 1DVAL 1IJQA 2KL7A 1TLEA 1U67A 1LPGA 2J38B 2W2ME 3R05A 2WG4B 1CEJA 4OTYA 4BXWA 1EGFA 2TGFA 1ADXA 4LMFA 4ZXYL 1ATDA 4Z6AL 2P3UA 2KB9A 4BTIA 1NQLB 1NZIA 2G00L 1G2MB 1G2LB 3FBYA 1DQBA 1FSBA 1IQGL 3CS7L 4JZEL 2BOXA 5KIRA 2Y5GL 1WHFA 1WHEA 1EPIA 1IOXA 1CCVA 1HJ7A 3P5BL 2BOUA 2P93L 1BF9A 2P28B 2BQ7A 3GCWE 1P0SL 2H9EL 3SOBB 2FLRL 1IQEL 1CVUA 2BO2A 3ZYGA 1N1IA 1NFXB 2MHPA 4CUDA 4D0FA 4YT7L 4RUTA 2WYJB 2FD6A 4ZXXL 1AUTL 5F19A 2VWLL 1FF7A 2Y38A 3IITB 4ISIL 1FE2A 4JYVL 4JZDL 3U7UG 1RFNB 2CJIB 3TBDA 1UZQA 1IQNL 3IJEB 3SW2A 1DDXA 3TK5B 2VVUL 2YGPA 2OYEP 5IKTA 3BT1A 3QMOA 4Z0KB 2VVVL 5JVZA 4XLWA 2XC5L 2VWOL 3NT1A 3BT2A 4CSYA 1NT0A 1GK5A 1IQKL 5JB8E 4JZFL 2P26A 1KLIL 1M1XB 1X7AL 3KCGL 4FM5A 4NGAL 3HO3A 5CKMA 2W26B 2RA0L 3HS7A 5IKRA 2RNLA 4C16A 4OTJA 2B7DL 3HO5A 2VWMK 5JBAE 1IQHL 1APQA 4RRYA 5L2YL 2XBVL 2J4IB 2W3IB 3N8ZA 2UWLB 4LORA 1FAXL 5CISA
chains in the Genus database with same CATH superfamily
2P95L 2WPJE 1LQDA 4RRXA 3NTGA 2WPLE 1IQML 3TK6B 2Y82B 3ENSA 3HS5A 4BDWA 1IGZA 2W2NE 1NFUB 4D90A 2Q1JB 2Y5HL 2FLGA 3SOVA 3DEMA 4BXSA 3KK6A 5F1AA 4X8SL 2FLBL 1EAIC 1XDTR 1TPGA 5JBBE 1EPHA 4A7IA 2AYLA 1IQIL 2BQ6A 4PH9A 1EPJA 1Z6CA 2W86A 3N8VA 2WG3C 5L2ZL 1UZPA 1UZJA 1HREA 2KV4A 1MOXC 2VH6B 2PUQL 3EGFA 4XBMA 3F1SB 1YUGA 1P9JA 2PR3B 2HORA 1F7EA 3M36L 1L3YA 3KQBL 2P94L 3H5CB 2WPME 2K2TA 2WFXB 3LN0A 2XC4L 1PGEA 1HT8A 1EQGA 3Q3KB 2Y81B 1G1QA 3GISX 5JBCE 2W3KB 1HAEA 4MMYB 4RRZA 1KLOA 2K2SB 2UWOB 3PGHA 4G1MB 3N8WA 1XFEA 2BOKL 4Y7BB 1FAKL 3M37L 3N8WB 1IVOC 2XC0L 2M74A 4TGFA 4BTUA 1O5DL 1V1HA 3OLUA 2W2OE 2BMGA 1W8BL 1L5GB 1U8CB 1HCGB 2J95B 4JYUL 3K9XA 1YUKB 2WPIE 4D0EA 1JV2B 1K37A 4X8VL 1F0RB 1Q4GA 3ZYJB 4Y7AB 5E8DA 1ZAQA 1COUA 2P3FL 5I46L 5IKVA 1EBVA 1F7MA 3V64C 1LK9A 2WYGB 3HPTA 3KL6B 1CX2A 3MDLA 3ZYIB 1PXXA 3BPSE 3TGFA 2I9BA 4M10A 1HZ8A 1DIYA 1C5MF 4E1GA 4RS0A 2DDUA 1Z6EL 2XBYL 1ATEA 1J9CL 3MQEA 4MMXB 1A3PA 1MQ5L 3KQDL 3V65B 2MGRA 3KQEL 4NG9L 1CCFA 2RHPA 3POYA 2ADXA 4AQTA 4ISHL 4XL1A 2W2PE 2Y7ZB 1KSNB 1KIGL 4YZUB 3S6XA 1EQHA 2BOHA 3GCXE 3HS6A 3Q7DA 1SZBA 3KQCL 4CUFA 2W2QE 4Y79B 2BQWA 4YT6L 1HT5A 2FZZL 4MMZB 2F9BL 5CKNA 4A94C 1YO8A 5JW1A 1IQFL 1N7DA 1NFYB 5KN5C 1G1RA 1HRFA 1YUFA 2PHBB 4M11A 3NJPC 2WPHE 1MQ6L 2YGQA 1JBUL 3CENL 2XBXL 1FFMA 3U73A 1EZQB 1F0SB 1W7XL 1QFKL 2UWPB 3LN1A 3ELAL 1HAFA 2H9EC 2EI8B 2J94B 1URKA 2BT7A 4X8TL 1APOA 3HO4A 2XBWL 1OB1C 4CUEA 4ZAEB 4NA9L 1LMJA 3F6UL 1IP0A 1IOEL 1KLJL 2P3FN 3CFWA 1LPZA 3CA7A 5L30L 4COXA 3FCSB 1PRHA 2Y7XB 3N8XA 3RR3A 4O1ZA 4X8UL 2EI6B 2VJ3A 1V3XB 1LMMA 2Y5FL 1IQJL 5K0HB 3QCWA 1TOZA 3NTBA 2VVCK 2P3TA 4GU3A 2EI7B 4BTTA 2J34B 3LIWB 2I9AA 2GD4A 1CVWL 1G1TA 2D1JB 3C9AC 4Y76B 2BZ6L 1DX5I 1NPEB 3TH3L 4Z0LA 5COXA 1EPGA 1EMOA 4Y71B 5CKQA 1PTHA 2WPKE 1ATAA 1WU1B 1IQLL 1PFXL 2HOXA 2J2UB 3LAQA 2OYUP 3LC3B 2Y80B 2NPRA 5JVYA 5JB9E 4Y6DB 1EMNA 1NFWB 3FFGL 3LTFB 3LTGD 3LC5B 1K36A 2VH0B 5EGMB 3SOQA 1CQEA 1FJSL 3KRKA 2MGPA 1XKAL 1KKEA 1YGCL 1UZKA 4O02B 3N8YA 2P16L 4BDXA 1I0UA 3ASIA 1JL9A 1IGXA 1G1SA 2JKHL 4ZH8B 3N8YB 1B9WA 1ATBA 1QIUA 2YGOA 1HX2A 1XKBA 1V1IA 3QH0A 2WFTA 2VWNL 1LPKA 6COXA 4RRWA 5FDQA 4ZHAB 3OLTA 2VRSA 3TZIA 5IKQA 1DVAL 1IJQA 2KL7A 1TLEA 1U67A 1LPGA 2J38B 2W2ME 3R05A 2WG4B 1CEJA 4OTYA 4BXWA 1EGFA 2TGFA 1ADXA 4LMFA 4ZXYL 1ATDA 4Z6AL 2P3UA 2KB9A 4BTIA 1NQLB 1NZIA 2G00L 1G2MB 1G2LB 3FBYA 1DQBA 4GU4A 1FSBA 1IQGL 3CS7L 4JZEL 2BOXA 5KIRA 2WZPP 2JJLA 2Y5GL 1WHFA 1WHEA 1EPIA 1IOXA 1CCVA 1HJ7A 3P5BL 2BOUA 2P93L 1BF9A 2P28B 2BQ7A 3GCWE 1P0SL 2H9EL 3SOBB 2BSFA 2FLRL 1IQEL 1CVUA 2BO2A 3ZYGA 1N1IA 1NFXB 2MHPA 4CUDA 4D0FA 4YT7L 4RUTA 2WYJB 2FD6A 4ZXXL 1AUTL 5F19A 2VWLL 1FF7A 2Y38A 3IITB 4ISIL 2BT8A 1FE2A 4JYVL 4JZDL 3U7UG 1RFNB 2CJIB 3TBDA 1UZQA 1IQNL 3IJEB 3SW2A 1DDXA 3TK5B 2KNIA 2VVUL 2YGPA 2OYEP 5IKTA 3BT1A 3QMOA 4Z0KB 2VVVL 5JVZA 4XLWA 2XC5L 2VWOL 3NT1A 3BT2A 4CSYA 1NT0A 1GK5A 1IQKL 5JB8E 4JZFL 2P26A 1KLIL 1M1XB 1X7AL 3KCGL 4FM5A 4NGAL 3HO3A 5CKMA 2W26B 2RA0L 3HS7A 5IKRA 2RNLA 4C16A 4OTJA 2B7DL 3HO5A 2VWMK 5JBAE 1IQHL 1APQA 4RRYA 5L2YL 2XBVL 2J4IB 2W3IB 3N8ZA 2UWLB 4LORA 1FAXL 5CISA
chains in the Genus database with same CATH topology
2P95L 2WPJE 1LQDA 4RRXA 3NTGA 2WPLE 1IQML 3TK6B 2Y82B 3ENSA 3HS5A 4BDWA 1IGZA 2W2NE 1NFUB 4D90A 2Q1JB 2Y5HL 2FLGA 3SOVA 3DEMA 4BXSA 3KK6A 5F1AA 4X8SL 2FLBL 1EAIC 1XDTR 1TPGA 5JBBE 1EPHA 4A7IA 2AYLA 1IQIL 2BQ6A 4PH9A 1EPJA 1Z6CA 2W86A 3N8VA 2WG3C 5L2ZL 1UZPA 1UZJA 1HREA 2KV4A 1MOXC 2VH6B 2PUQL 3EGFA 4XBMA 3F1SB 1YUGA 1P9JA 2PR3B 1F7EA 3M36L 1L3YA 3KQBL 2P94L 3H5CB 2WPME 2K2TA 2WFXB 3LN0A 2XC4L 1PGEA 1HT8A 1EQGA 3Q3KB 2Y81B 1G1QA 3GISX 5JBCE 2W3KB 1HAEA 4MMYB 4RRZA 1KLOA 2K2SB 2UWOB 3PGHA 4G1MB 3N8WA 1XFEA 2BOKL 4Y7BB 1FAKL 3M37L 3N8WB 1IVOC 2M74A 2XC0L 4TGFA 4BTUA 1O5DL 3OLUA 2W2OE 2BMGA 1W8BL 1L5GB 1U8CB 1HCGB 2J95B 4JYUL 3K9XA 1YUKB 2WPIE 4D0EA 1JV2B 1K37A 4X8VL 1F0RB 1Q4GA 3ZYJB 4Y7AB 5E8DA 1ZAQA 1COUA 2P3FL 5I46L 5IKVA 1EBVA 1F7MA 3V64C 2WYGB 3HPTA 3KL6B 1CX2A 3MDLA 3ZYIB 1PXXA 3BPSE 3TGFA 2I9BA 4M10A 1HZ8A 1DIYA 1C5MF 4E1GA 4RS0A 2DDUA 1Z6EL 2XBYL 1ATEA 1J9CL 3MQEA 4MMXB 1A3PA 1MQ5L 3KQDL 3V65B 2MGRA 3KQEL 4NG9L 1CCFA 2RHPA 3POYA 2ADXA 4AQTA 4ISHL 4XL1A 2W2PE 2Y7ZB 1KSNB 1KIGL 4YZUB 3S6XA 1EQHA 2BOHA 3GCXE 3HS6A 3Q7DA 1SZBA 3KQCL 4CUFA 2W2QE 4Y79B 2BQWA 4YT6L 1HT5A 2FZZL 4MMZB 2F9BL 5CKNA 4A94C 1YO8A 5JW1A 1IQFL 1N7DA 1NFYB 5KN5C 1G1RA 1HRFA 1YUFA 2PHBB 4M11A 3NJPC 2WPHE 1MQ6L 2YGQA 1JBUL 3CENL 2XBXL 1FFMA 3U73A 1EZQB 1F0SB 1W7XL 1QFKL 2UWPB 3LN1A 3ELAL 1HAFA 2H9EC 2EI8B 2J94B 1URKA 4X8TL 1APOA 3HO4A 2XBWL 1OB1C 4CUEA 4ZAEB 4NA9L 1LMJA 3F6UL 1IP0A 1IOEL 1KLJL 2P3FN 3CFWA 1LPZA 3CA7A 5L30L 4COXA 3FCSB 1PRHA 2Y7XB 3N8XA 3RR3A 4O1ZA 4X8UL 2EI6B 2VJ3A 1V3XB 1LMMA 2Y5FL 1IQJL 5K0HB 3QCWA 1TOZA 3NTBA 2VVCK 2P3TA 2EI7B 4BTTA 2J34B 3LIWB 2I9AA 2GD4A 1CVWL 1G1TA 2D1JB 3C9AC 4Y76B 2BZ6L 1DX5I 1NPEB 3TH3L 4Z0LA 5COXA 1EPGA 1EMOA 4Y71B 5CKQA 1PTHA 2WPKE 1ATAA 1WU1B 1IQLL 1PFXL 2J2UB 3LAQA 2OYUP 3LC3B 2Y80B 2NPRA 5JVYA 5JB9E 4Y6DB 1EMNA 1NFWB 3FFGL 3LTFB 3LTGD 3LC5B 1K36A 2VH0B 5EGMB 3SOQA 1CQEA 1FJSL 3KRKA 2MGPA 1XKAL 1YGCL 1UZKA 4O02B 3N8YA 2P16L 4BDXA 1I0UA 3ASIA 1JL9A 1IGXA 1G1SA 2JKHL 4ZH8B 3N8YB 1B9WA 1ATBA 2YGOA 1HX2A 1XKBA 3QH0A 2WFTA 2VWNL 1LPKA 6COXA 4RRWA 5FDQA 4ZHAB 3OLTA 3TZIA 5IKQA 1DVAL 1IJQA 2KL7A 1TLEA 1U67A 1LPGA 2J38B 2W2ME 3R05A 2WG4B 1CEJA 4OTYA 4BXWA 1EGFA 2TGFA 1ADXA 4LMFA 4ZXYL 1ATDA 4Z6AL 2P3UA 2KB9A 4BTIA 1NQLB 1NZIA 2G00L 1G2MB 1G2LB 3FBYA 1DQBA 1FSBA 1IQGL 3CS7L 4JZEL 2BOXA 5KIRA 2WZPP 2Y5GL 1WHFA 1WHEA 1EPIA 1IOXA 1CCVA 1HJ7A 3P5BL 2BOUA 2P93L 1BF9A 2P28B 2BQ7A 3GCWE 1P0SL 2H9EL 3SOBB 2FLRL 1IQEL 1CVUA 2BO2A 3ZYGA 1N1IA 1NFXB 2MHPA 4CUDA 4D0FA 4YT7L 4RUTA 2WYJB 2FD6A 4ZXXL 1AUTL 5F19A 2VWLL 1FF7A 2Y38A 3IITB 4ISIL 1FE2A 4JYVL 4JZDL 3U7UG 1RFNB 2CJIB 3TBDA 1UZQA 1IQNL 3IJEB 3SW2A 1DDXA 3TK5B 2KNIA 2VVUL 2YGPA 2OYEP 5IKTA 3BT1A 3QMOA 4Z0KB 2VVVL 5JVZA 4XLWA 2XC5L 2VWOL 3NT1A 3BT2A 4CSYA 1NT0A 1GK5A 1IQKL 5JB8E 4JZFL 2P26A 1KLIL 1M1XB 1X7AL 3KCGL 4FM5A 4NGAL 3HO3A 5CKMA 2W26B 2RA0L 3HS7A 5IKRA 2RNLA 4C16A 4OTJA 2B7DL 3HO5A 2VWMK 5JBAE 1IQHL 1APQA 4RRYA 5L2YL 2XBVL 2J4IB 2W3IB 3N8ZA 2UWLB 4LORA 1FAXL 5CISA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P95 L;  2WPJ E;  1LQD A;  4RRX A;  3NTG A;  2WPL E;  1IQM L;  3TK6 B;  2Y82 B;  3ENS A;  3HS5 A;  4BDW A;  1IGZ A;  2W2N E;  1NFU B;  4D90 A;  2Q1J B;  2Y5H L;  2FLG A;  3SOV A;  3DEM A;  4BXS A;  3KK6 A;  5F1A A;  4X8S L;  2FLB L;  1EAI C;  1XDT R;  1TPG A;  5JBB E;  1EPH A;  4A7I A;  2AYL A;  1IQI L;  2BQ6 A;  4PH9 A;  1EPJ A;  1Z6C A;  2W86 A;  3N8V A;  2WG3 C;  5L2Z L;  1UZP A;  1UZJ A;  1HRE A;  2KV4 A;  1MOX C;  2VH6 B;  2PUQ L;  3EGF A;  4XBM A;  3F1S B;  1YUG A;  1P9J A;  2PR3 B;  1F7E A;  3M36 L;  1L3Y A;  3KQB L;  2P94 L;  3H5C B;  2WPM E;  2K2T A;  2WFX B;  3LN0 A;  2XC4 L;  1PGE A;  1HT8 A;  1EQG A;  3Q3K B;  2Y81 B;  1G1Q A;  3GIS X;  5JBC E;  2W3K B;  1HAE A;  4MMY B;  4RRZ A;  1KLO A;  2K2S B;  2UWO B;  3PGH A;  4G1M B;  3N8W A;  1XFE A;  2BOK L;  4Y7B B;  1FAK L;  3M37 L;  3N8W B;  1IVO C;  2M74 A;  2XC0 L;  4TGF A;  4BTU A;  1O5D L;  3OLU A;  2W2O E;  2BMG A;  1W8B L;  1L5G B;  1U8C B;  1HCG B;  2J95 B;  4JYU L;  3K9X A;  1YUK B;  2WPI E;  4D0E A;  1JV2 B;  1K37 A;  4X8V L;  1F0R B;  1Q4G A;  3ZYJ B;  4Y7A B;  5E8D A;  1ZAQ A;  1COU A;  2P3F L;  5I46 L;  5IKV A;  1EBV A;  1F7M A;  3V64 C;  2WYG B;  3HPT A;  3KL6 B;  1CX2 A;  3MDL A;  3ZYI B;  1PXX A;  3BPS E;  3TGF A;  2I9B A;  4M10 A;  1HZ8 A;  1DIY A;  1C5M F;  4E1G A;  4RS0 A;  2DDU A;  1Z6E L;  2XBY L;  1ATE A;  1J9C L;  3MQE A;  4MMX B;  1A3P A;  1MQ5 L;  3KQD L;  3V65 B;  2MGR A;  3KQE L;  4NG9 L;  1CCF A;  2RHP A;  3POY A;  2ADX A;  4AQT A;  4ISH L;  4XL1 A;  2W2P E;  2Y7Z B;  1KSN B;  1KIG L;  4YZU B;  1EQH A;  2BOH A;  3GCX E;  3HS6 A;  3Q7D A;  1SZB A;  3KQC L;  4CUF A;  2W2Q E;  4Y79 B;  2BQW A;  4YT6 L;  1HT5 A;  2FZZ L;  4MMZ B;  2F9B L;  5CKN A;  1YO8 A;  5JW1 A;  1IQF L;  1N7D A;  1NFY B;  5KN5 C;  1G1R A;  1HRF A;  1YUF A;  2PHB B;  4M11 A;  3NJP C;  2WPH E;  1MQ6 L;  1JBU L;  3CEN L;  2XBX L;  1FFM A;  3U73 A;  1EZQ B;  1F0S B;  1W7X L;  1QFK L;  2UWP B;  3LN1 A;  3ELA L;  1HAF A;  2EI8 B;  2J94 B;  1URK A;  4X8T L;  1APO A;  3HO4 A;  2XBW L;  1OB1 C;  4CUE A;  4ZAE B;  4NA9 L;  1LMJ A;  3F6U L;  1IP0 A;  1IOE L;  1KLJ L;  2P3F N;  3CFW A;  1LPZ A;  3CA7 A;  5L30 L;  4COX A;  3FCS B;  1PRH A;  2Y7X B;  3N8X A;  3RR3 A;  4O1Z A;  4X8U L;  2EI6 B;  2VJ3 A;  1V3X B;  2Y5F L;  1IQJ L;  5K0H B;  3QCW A;  1TOZ A;  3NTB A;  2VVC K;  2P3T A;  2EI7 B;  4BTT A;  2J34 B;  3LIW B;  2I9A A;  2GD4 A;  1CVW L;  1G1T A;  2D1J B;  3C9A C;  4Y76 B;  2BZ6 L;  1DX5 I;  1NPE B;  3TH3 L;  4Z0L A;  5COX A;  1EPG A;  1EMO A;  4Y71 B;  5CKQ A;  1PTH A;  2WPK E;  1ATA A;  1WU1 B;  1IQL L;  1PFX L;  2J2U B;  3LAQ A;  2OYU P;  3LC3 B;  2Y80 B;  2NPR A;  5JVY A;  5JB9 E;  4Y6D B;  1EMN A;  1NFW B;  3FFG L;  3LTF B;  3LTG D;  3LC5 B;  1K36 A;  2VH0 B;  5EGM B;  3SOQ A;  1CQE A;  1FJS L;  3KRK A;  2MGP A;  1XKA L;  1YGC L;  1UZK A;  4O02 B;  3N8Y A;  2P16 L;  4BDX A;  1I0U A;  3ASI A;  1JL9 A;  1IGX A;  1G1S A;  2JKH L;  4ZH8 B;  3N8Y B;  1B9W A;  1ATB A;  2YGO A;  1HX2 A;  1XKB A;  3QH0 A;  2WFT A;  2VWN L;  1LPK A;  6COX A;  4RRW A;  5FDQ A;  4ZHA B;  3OLT A;  3TZI A;  5IKQ A;  1DVA L;  1IJQ A;  2KL7 A;  1TLE A;  1U67 A;  1LPG A;  2J38 B;  2W2M E;  3R05 A;  2WG4 B;  1CEJ A;  4OTY A;  4BXW A;  1EGF A;  2TGF A;  1ADX A;  4LMF A;  4ZXY L;  1ATD A;  4Z6A L;  2P3U A;  2KB9 A;  4BTI A;  1NQL B;  1NZI A;  2G00 L;  1G2M B;  1G2L B;  3FBY A;  1DQB A;  1FSB A;  1IQG L;  3CS7 L;  4JZE L;  2BOX A;  5KIR A;  2Y5G L;  1WHF A;  1WHE A;  1EPI A;  1IOX A;  1CCV A;  1HJ7 A;  3P5B L;  2BOU A;  2P93 L;  1BF9 A;  2P28 B;  2BQ7 A;  3GCW E;  1P0S L;  2H9E L;  3SOB B;  2FLR L;  1IQE L;  1CVU A;  2BO2 A;  3ZYG A;  1N1I A;  1NFX B;  2MHP A;  4CUD A;  4D0F A;  4YT7 L;  4RUT A;  2WYJ B;  2FD6 A;  4ZXX L;  1AUT L;  5F19 A;  2VWL L;  1FF7 A;  2Y38 A;  3IIT B;  4ISI L;  1FE2 A;  4JYV L;  4JZD L;  3U7U G;  1RFN B;  2CJI B;  3TBD A;  1UZQ A;  1IQN L;  3IJE B;  3SW2 A;  1DDX A;  3TK5 B;  2VVU L;  2YGP A;  2OYE P;  5IKT A;  3BT1 A;  3QMO A;  4Z0K B;  2VVV L;  5JVZ A;  4XLW A;  2XC5 L;  2VWO L;  3NT1 A;  3BT2 A;  4CSY A;  1NT0 A;  1GK5 A;  1IQK L;  5JB8 E;  4JZF L;  2P26 A;  1KLI L;  1M1X B;  1X7A L;  3KCG L;  4FM5 A;  4NGA L;  3HO3 A;  5CKM A;  2W26 B;  2RA0 L;  3HS7 A;  5IKR A;  2RNL A;  4C16 A;  4OTJ A;  2B7D L;  3HO5 A;  2VWM K;  5JBA E;  1IQH L;  1APQ A;  4RRY A;  5L2Y L;  2XBV L;  2J4I B;  2W3I B;  3N8Z A;  2UWL B;  4LOR A;  1FAX L;  5CIS A; 
#chains in the Genus database with same CATH topology
 2P95 L;  2WPJ E;  1LQD A;  4RRX A;  3NTG A;  2WPL E;  1IQM L;  3TK6 B;  2Y82 B;  3ENS A;  3HS5 A;  4BDW A;  1IGZ A;  2W2N E;  1NFU B;  4D90 A;  2Q1J B;  2Y5H L;  2FLG A;  3SOV A;  3DEM A;  4BXS A;  3KK6 A;  5F1A A;  4X8S L;  2FLB L;  1EAI C;  1XDT R;  1TPG A;  5JBB E;  1EPH A;  4A7I A;  2AYL A;  1IQI L;  2BQ6 A;  4PH9 A;  1EPJ A;  1Z6C A;  2W86 A;  3N8V A;  2WG3 C;  5L2Z L;  1UZP A;  1UZJ A;  1HRE A;  2KV4 A;  1MOX C;  2VH6 B;  2PUQ L;  3EGF A;  4XBM A;  3F1S B;  1YUG A;  1P9J A;  2PR3 B;  2HOR A;  1F7E A;  3M36 L;  1L3Y A;  3KQB L;  2P94 L;  3H5C B;  2WPM E;  2K2T A;  2WFX B;  3LN0 A;  2XC4 L;  1PGE A;  1HT8 A;  1EQG A;  3Q3K B;  2Y81 B;  1G1Q A;  3GIS X;  5JBC E;  2W3K B;  1HAE A;  4MMY B;  4RRZ A;  1KLO A;  2K2S B;  2UWO B;  3PGH A;  4G1M B;  3N8W A;  1XFE A;  2BOK L;  4Y7B B;  1FAK L;  3M37 L;  3N8W B;  1IVO C;  2XC0 L;  2M74 A;  4TGF A;  4BTU A;  1O5D L;  1V1H A;  3OLU A;  2W2O E;  2BMG A;  1W8B L;  1L5G B;  1U8C B;  1HCG B;  2J95 B;  4JYU L;  3K9X A;  1YUK B;  2WPI E;  4D0E A;  1JV2 B;  1K37 A;  4X8V L;  1F0R B;  1Q4G A;  3ZYJ B;  4Y7A B;  5E8D A;  1ZAQ A;  1COU A;  2P3F L;  5I46 L;  5IKV A;  1EBV A;  1F7M A;  3V64 C;  1LK9 A;  2WYG B;  3HPT A;  3KL6 B;  1CX2 A;  3MDL A;  3ZYI B;  1PXX A;  3BPS E;  3TGF A;  2I9B A;  4M10 A;  1HZ8 A;  1DIY A;  1C5M F;  4E1G A;  4RS0 A;  2DDU A;  1Z6E L;  2XBY L;  1ATE A;  1J9C L;  3MQE A;  4MMX B;  1A3P A;  1MQ5 L;  3KQD L;  3V65 B;  2MGR A;  3KQE L;  4NG9 L;  1CCF A;  2RHP A;  3POY A;  2ADX A;  4AQT A;  4ISH L;  4XL1 A;  2W2P E;  2Y7Z B;  1KSN B;  1KIG L;  4YZU B;  3S6X A;  1EQH A;  2BOH A;  3GCX E;  3HS6 A;  3Q7D A;  1SZB A;  3KQC L;  4CUF A;  2W2Q E;  4Y79 B;  2BQW A;  4YT6 L;  1HT5 A;  2FZZ L;  4MMZ B;  2F9B L;  5CKN A;  4A94 C;  1YO8 A;  5JW1 A;  1IQF L;  1N7D A;  1NFY B;  5KN5 C;  1G1R A;  1HRF A;  1YUF A;  2PHB B;  4M11 A;  3NJP C;  2WPH E;  1MQ6 L;  2YGQ A;  1JBU L;  3CEN L;  2XBX L;  1FFM A;  3U73 A;  1EZQ B;  1F0S B;  1W7X L;  1QFK L;  2UWP B;  3LN1 A;  3ELA L;  1HAF A;  2H9E C;  2EI8 B;  2J94 B;  1URK A;  2BT7 A;  4X8T L;  1APO A;  3HO4 A;  2XBW L;  1OB1 C;  4CUE A;  4ZAE B;  4NA9 L;  1LMJ A;  3F6U L;  1IP0 A;  1IOE L;  1KLJ L;  2P3F N;  3CFW A;  1LPZ A;  3CA7 A;  5L30 L;  4COX A;  3FCS B;  1PRH A;  2Y7X B;  3N8X A;  3RR3 A;  4O1Z A;  4X8U L;  2EI6 B;  2VJ3 A;  1V3X B;  1LMM A;  2Y5F L;  1IQJ L;  5K0H B;  3QCW A;  1TOZ A;  3NTB A;  2VVC K;  2P3T A;  4GU3 A;  2EI7 B;  4BTT A;  2J34 B;  3LIW B;  2I9A A;  2GD4 A;  1CVW L;  1G1T A;  2D1J B;  3C9A C;  4Y76 B;  2BZ6 L;  1DX5 I;  1NPE B;  3TH3 L;  4Z0L A;  5COX A;  1EPG A;  1EMO A;  4Y71 B;  5CKQ A;  1PTH A;  2WPK E;  1ATA A;  1WU1 B;  1IQL L;  1PFX L;  2HOX A;  2J2U B;  3LAQ A;  2OYU P;  3LC3 B;  2Y80 B;  2NPR A;  5JVY A;  5JB9 E;  4Y6D B;  1EMN A;  1NFW B;  3FFG L;  3LTF B;  3LTG D;  3LC5 B;  1K36 A;  2VH0 B;  5EGM B;  3SOQ A;  1CQE A;  1FJS L;  3KRK A;  2MGP A;  1XKA L;  1KKE A;  1YGC L;  1UZK A;  4O02 B;  3N8Y A;  2P16 L;  4BDX A;  1I0U A;  3ASI A;  1JL9 A;  1IGX A;  1G1S A;  2JKH L;  4ZH8 B;  3N8Y B;  1B9W A;  1ATB A;  1QIU A;  2YGO A;  1HX2 A;  1XKB A;  1V1I A;  3QH0 A;  2WFT A;  2VWN L;  1LPK A;  6COX A;  4RRW A;  5FDQ A;  4ZHA B;  3OLT A;  2VRS A;  3TZI A;  5IKQ A;  1DVA L;  1IJQ A;  2KL7 A;  1TLE A;  1U67 A;  1LPG A;  2J38 B;  2W2M E;  3R05 A;  2WG4 B;  1CEJ A;  4OTY A;  4BXW A;  1EGF A;  2TGF A;  1ADX A;  4LMF A;  4ZXY L;  1ATD A;  4Z6A L;  2P3U A;  2KB9 A;  4BTI A;  1NQL B;  1NZI A;  2G00 L;  1G2M B;  1G2L B;  3FBY A;  1DQB A;  4GU4 A;  1FSB A;  1IQG L;  3CS7 L;  4JZE L;  2BOX A;  5KIR A;  2WZP P;  2JJL A;  2Y5G L;  1WHF A;  1WHE A;  1EPI A;  1IOX A;  1CCV A;  1HJ7 A;  3P5B L;  2BOU A;  2P93 L;  1BF9 A;  2P28 B;  2BQ7 A;  3GCW E;  1P0S L;  2H9E L;  3SOB B;  2BSF A;  2FLR L;  1IQE L;  1CVU A;  2BO2 A;  3ZYG A;  1N1I A;  1NFX B;  2MHP A;  4CUD A;  4D0F A;  4YT7 L;  4RUT A;  2WYJ B;  2FD6 A;  4ZXX L;  1AUT L;  5F19 A;  2VWL L;  1FF7 A;  2Y38 A;  3IIT B;  4ISI L;  2BT8 A;  1FE2 A;  4JYV L;  4JZD L;  3U7U G;  1RFN B;  2CJI B;  3TBD A;  1UZQ A;  1IQN L;  3IJE B;  3SW2 A;  1DDX A;  3TK5 B;  2KNI A;  2VVU L;  2YGP A;  2OYE P;  5IKT A;  3BT1 A;  3QMO A;  4Z0K B;  2VVV L;  5JVZ A;  4XLW A;  2XC5 L;  2VWO L;  3NT1 A;  3BT2 A;  4CSY A;  1NT0 A;  1GK5 A;  1IQK L;  5JB8 E;  4JZF L;  2P26 A;  1KLI L;  1M1X B;  1X7A L;  3KCG L;  4FM5 A;  4NGA L;  3HO3 A;  5CKM A;  2W26 B;  2RA0 L;  3HS7 A;  5IKR A;  2RNL A;  4C16 A;  4OTJ A;  2B7D L;  3HO5 A;  2VWM K;  5JBA E;  1IQH L;  1APQ A;  4RRY A;  5L2Y L;  2XBV L;  2J4I B;  2W3I B;  3N8Z A;  2UWL B;  4LOR A;  1FAX L;  5CIS A; 
#chains in the Genus database with same CATH homology
 2P95 L;  2WPJ E;  1LQD A;  4RRX A;  3NTG A;  2WPL E;  1IQM L;  3TK6 B;  2Y82 B;  3ENS A;  3HS5 A;  4BDW A;  1IGZ A;  2W2N E;  1NFU B;  4D90 A;  2Q1J B;  2Y5H L;  2FLG A;  3SOV A;  3DEM A;  4BXS A;  3KK6 A;  5F1A A;  4X8S L;  2FLB L;  1EAI C;  1XDT R;  1TPG A;  5JBB E;  1EPH A;  4A7I A;  2AYL A;  1IQI L;  2BQ6 A;  4PH9 A;  1EPJ A;  1Z6C A;  2W86 A;  3N8V A;  2WG3 C;  5L2Z L;  1UZP A;  1UZJ A;  1HRE A;  2KV4 A;  1MOX C;  2VH6 B;  2PUQ L;  3EGF A;  4XBM A;  3F1S B;  1YUG A;  1P9J A;  2PR3 B;  1F7E A;  3M36 L;  1L3Y A;  3KQB L;  2P94 L;  3H5C B;  2WPM E;  2K2T A;  2WFX B;  3LN0 A;  2XC4 L;  1PGE A;  1HT8 A;  1EQG A;  3Q3K B;  2Y81 B;  1G1Q A;  3GIS X;  5JBC E;  2W3K B;  1HAE A;  4MMY B;  4RRZ A;  1KLO A;  2K2S B;  2UWO B;  3PGH A;  4G1M B;  3N8W A;  1XFE A;  2BOK L;  4Y7B B;  1FAK L;  3M37 L;  3N8W B;  1IVO C;  2M74 A;  2XC0 L;  4TGF A;  4BTU A;  1O5D L;  3OLU A;  2W2O E;  2BMG A;  1W8B L;  1L5G B;  1U8C B;  1HCG B;  2J95 B;  4JYU L;  3K9X A;  1YUK B;  2WPI E;  4D0E A;  1JV2 B;  1K37 A;  4X8V L;  1F0R B;  1Q4G A;  3ZYJ B;  4Y7A B;  5E8D A;  1ZAQ A;  1COU A;  2P3F L;  5I46 L;  5IKV A;  1EBV A;  1F7M A;  3V64 C;  2WYG B;  3HPT A;  3KL6 B;  1CX2 A;  3MDL A;  3ZYI B;  1PXX A;  3BPS E;  3TGF A;  2I9B A;  4M10 A;  1HZ8 A;  1DIY A;  1C5M F;  4E1G A;  4RS0 A;  2DDU A;  1Z6E L;  2XBY L;  1ATE A;  1J9C L;  3MQE A;  4MMX B;  1A3P A;  1MQ5 L;  3KQD L;  3V65 B;  2MGR A;  3KQE L;  4NG9 L;  1CCF A;  2RHP A;  3POY A;  2ADX A;  4AQT A;  4ISH L;  4XL1 A;  2W2P E;  2Y7Z B;  1KSN B;  1KIG L;  4YZU B;  3S6X A;  1EQH A;  2BOH A;  3GCX E;  3HS6 A;  3Q7D A;  1SZB A;  3KQC L;  4CUF A;  2W2Q E;  4Y79 B;  2BQW A;  4YT6 L;  1HT5 A;  2FZZ L;  4MMZ B;  2F9B L;  5CKN A;  4A94 C;  1YO8 A;  5JW1 A;  1IQF L;  1N7D A;  1NFY B;  5KN5 C;  1G1R A;  1HRF A;  1YUF A;  2PHB B;  4M11 A;  3NJP C;  2WPH E;  1MQ6 L;  2YGQ A;  1JBU L;  3CEN L;  2XBX L;  1FFM A;  3U73 A;  1EZQ B;  1F0S B;  1W7X L;  1QFK L;  2UWP B;  3LN1 A;  3ELA L;  1HAF A;  2H9E C;  2EI8 B;  2J94 B;  1URK A;  4X8T L;  1APO A;  3HO4 A;  2XBW L;  1OB1 C;  4CUE A;  4ZAE B;  4NA9 L;  1LMJ A;  3F6U L;  1IP0 A;  1IOE L;  1KLJ L;  2P3F N;  3CFW A;  1LPZ A;  3CA7 A;  5L30 L;  4COX A;  3FCS B;  1PRH A;  2Y7X B;  3N8X A;  3RR3 A;  4O1Z A;  4X8U L;  2EI6 B;  2VJ3 A;  1V3X B;  1LMM A;  2Y5F L;  1IQJ L;  5K0H B;  3QCW A;  1TOZ A;  3NTB A;  2VVC K;  2P3T A;  2EI7 B;  4BTT A;  2J34 B;  3LIW B;  2I9A A;  2GD4 A;  1CVW L;  1G1T A;  2D1J B;  3C9A C;  4Y76 B;  2BZ6 L;  1DX5 I;  1NPE B;  3TH3 L;  4Z0L A;  5COX A;  1EPG A;  1EMO A;  4Y71 B;  5CKQ A;  1PTH A;  2WPK E;  1ATA A;  1WU1 B;  1IQL L;  1PFX L;  2J2U B;  3LAQ A;  2OYU P;  3LC3 B;  2Y80 B;  2NPR A;  5JVY A;  5JB9 E;  4Y6D B;  1EMN A;  1NFW B;  3FFG L;  3LTF B;  3LTG D;  3LC5 B;  1K36 A;  2VH0 B;  5EGM B;  3SOQ A;  1CQE A;  1FJS L;  3KRK A;  2MGP A;  1XKA L;  1YGC L;  1UZK A;  4O02 B;  3N8Y A;  2P16 L;  4BDX A;  1I0U A;  3ASI A;  1JL9 A;  1IGX A;  1G1S A;  2JKH L;  4ZH8 B;  3N8Y B;  1B9W A;  1ATB A;  2YGO A;  1HX2 A;  1XKB A;  3QH0 A;  2WFT A;  2VWN L;  1LPK A;  6COX A;  4RRW A;  5FDQ A;  4ZHA B;  3OLT A;  3TZI A;  5IKQ A;  1DVA L;  1IJQ A;  2KL7 A;  1TLE A;  1U67 A;  1LPG A;  2J38 B;  2W2M E;  3R05 A;  2WG4 B;  1CEJ A;  4OTY A;  4BXW A;  1EGF A;  2TGF A;  1ADX A;  4LMF A;  4ZXY L;  1ATD A;  4Z6A L;  2P3U A;  2KB9 A;  4BTI A;  1NQL B;  1NZI A;  2G00 L;  1G2M B;  1G2L B;  3FBY A;  1DQB A;  1FSB A;  1IQG L;  3CS7 L;  4JZE L;  2BOX A;  5KIR A;  2WZP P;  2Y5G L;  1WHF A;  1WHE A;  1EPI A;  1IOX A;  1CCV A;  1HJ7 A;  3P5B L;  2BOU A;  2P93 L;  1BF9 A;  2P28 B;  2BQ7 A;  3GCW E;  1P0S L;  2H9E L;  3SOB B;  2FLR L;  1IQE L;  1CVU A;  2BO2 A;  3ZYG A;  1N1I A;  1NFX B;  2MHP A;  4CUD A;  4D0F A;  4YT7 L;  4RUT A;  2WYJ B;  2FD6 A;  4ZXX L;  1AUT L;  5F19 A;  2VWL L;  1FF7 A;  2Y38 A;  3IIT B;  4ISI L;  1FE2 A;  4JYV L;  4JZD L;  3U7U G;  1RFN B;  2CJI B;  3TBD A;  1UZQ A;  1IQN L;  3IJE B;  3SW2 A;  1DDX A;  3TK5 B;  2KNI A;  2VVU L;  2YGP A;  2OYE P;  5IKT A;  3BT1 A;  3QMO A;  4Z0K B;  2VVV L;  5JVZ A;  4XLW A;  2XC5 L;  2VWO L;  3NT1 A;  3BT2 A;  4CSY A;  1NT0 A;  1GK5 A;  1IQK L;  5JB8 E;  4JZF L;  2P26 A;  1KLI L;  1M1X B;  1X7A L;  3KCG L;  4FM5 A;  4NGA L;  3HO3 A;  5CKM A;  2W26 B;  2RA0 L;  3HS7 A;  5IKR A;  2RNL A;  4C16 A;  4OTJ A;  2B7D L;  3HO5 A;  2VWM K;  5JBA E;  1IQH L;  1APQ A;  4RRY A;  5L2Y L;  2XBV L;  2J4I B;  2W3I B;  3N8Z A;  2UWL B;  4LOR A;  1FAX L;  5CIS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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