2XBYL

Factor xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
50
structure length
43
Chain Sequence
CSLDNGDCDQFCVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a Factor Xa Inhibitor (3R,4R)-1-(2,2-Difluoro-Ethyl)-Pyrrolidine-3,4-Dicarboxylic Acid 3-[(5-Chloro-Pyridin-2-Yl)-Amide] 4-{[2-Fluoro-4-(2-Oxo-2H-Pyridin-1-Yl)-Phenyl]-Amide} as a Clinical Candidate.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 6
structure length 43
sequence length 50
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2010-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2xbyL00
3BT1A 1IP0A 1DX5I 1KLJL 3PGHA 1EGFA 1PTHA 4C16A 2Y38A 1IGZA 5CKQA 2KL7A 3LTFB 2Y81B 5JB9E 1ZAQA 1LPZA 4ZXYL 1NFYB 1IQIL 1EMNA 2UWLB 3CS7L 3HS6A 4BTUA 1YO8A 1Z6EL 1PXXA 1U67A 1DQBA 1IQKL 1J9CL 2Y5FL 4NGAL 5L2ZL 4CSYA 1EPIA 2W2OE 4CUFA 3CENL 4RS0A 3LAQA 1GK5A 4LORA 1U8CB 2J94B 2PUQL 1YUGA 4Z6AL 1HZ8A 1F0SB 4ZHAB 3CA7A 1EQGA 3SOQA 5JB8E 1HT5A 4MMYB 2WFXB 5L2YL 2WPLE 1FF7A 1G1TA 1UZQA 4O02B 3LC5B 3V65B 4FM5A 2MHPA 3ASIA 1BF9A 1RFNB 3N8YB 2XC5L 5FDQA 1OB1C 3LN0A 2P95L 2P3UA 2DDUA 4RUTA 1EQHA 3SOVA 3M37L 3Q3KB 2UWPB 3BT2A 2WYJB 2W3KB 1Z6CA 5JBBE 1IQLL 3FCSB 1UZPA 1L3YA 1EAIC 1DDXA 3V64C 2XBXL 1WU1B 1AUTL 1LPKA 1G1RA 2Y80B 2Q1JB 2OYEP 2XC4L 2BOXA 3KCGL 4PH9A 2YGPA 1ATAA 3LN1A 3HO4A 3POYA 1P9JA 2H9EL 4D0FA 4TGFA 1WHFA 2BOHA 1MQ6L 2PR3B 4RRXA 1ADXA 2WPJE 2RA0L 1X7AL 1FJSL 4JZEL 4ISHL 1FAKL 2K2TA 5CKNA 2W26B 1XDTR 2B7DL 3OLTA 1FSBA 4NG9L 1L5GB 2RNLA 1UZKA 4O1ZA 1IQFL 1IVOC 1N7DA 3BPSE 2P28B 2YGOA 1LPGA 2W3IB 3RR3A 1HX2A 2BOUA 1K36A 1EZQB 3TK5B 2K2SB 1IQNL 4XBMA 3N8XA 4AQTA 1TOZA 1LQDA 1ATBA 3N8WB 2Y5HL 2OYUP 2WPKE 1G1QA 2ADXA 2F9BL 2W2NE 1MQ5L 3SW2A 2WG4B 1V3XB 5CISA 1IOEL 1MOXC 2VWOL 1APOA 4ISIL 1UZJA 5I46L 1W8BL 1I0UA 3FBYA 1HCGB 5JBCE 2FLBL 1P0SL 4BXWA 5F1AA 2MGRA 3H5CB 1KLIL 4Z0KB 2G00L 1EPGA 4BDWA 2J34B 3GCWE 4M10A 3KL6B 5E8DA 2BMGA 2P16L 3C9AC 1NQLB 2BO2A 4XLWA 1CVWL 1PGEA 1QFKL 2VH6B 1G2MB 4COXA 3FFGL 5K0HB 2Y7ZB 3KQEL 3OLUA 1F7MA 1NT0A 4BXSA 1G2LB 4ZH8B 5IKTA 1APQA 2W2PE 2VWMK 5KIRA 5L30L 1EBVA 2BQ6A 2MGPA 1CVUA 3KQDL 1A3PA 3TH3L 5CKMA 1M1XB 2FZZL 3N8ZA 4JYVL 4X8UL 3NT1A 2WPHE 2W86A 2J2UB 3ENSA 1IQJL 2CJIB 4BTTA 3NJPC 3IJEB 1CEJA 1YUFA 1C5MF 4OTJA 3KRKA 3LC3B 3F1SB 4Y6DB 3TZIA 3NTBA 4YT6L 4OTYA 2BQ7A 5COXA 2NPRA 2GD4A 2W2QE 2WFTA 3HPTA 1JV2B 1HAFA 3KQCL 1CCFA 1YUKB 4M11A 2XC0L 3ZYGA 1TPGA 1XKBA 2VH0B 3MDLA 3N8YA 4Z0LA 1IQML 2Y7XB 1NPEB 1IOXA 3Q7DA 3N8VA 1KLOA 4D0EA 1SZBA 1O5DL 2P26A 1F7EA 3KQBL 3ELAL 4XL1A 3SOBB 4Y7AB 1PRHA 1NFUB 2EI6B 2P3FN 2Y82B 4D90A 3DEMA 1XFEA 2J95B 2FD6A 1IQHL 1DVAL 3QH0A 3CFWA 4JYUL 1FFMA 2WG3C 3QCWA 5JW1A 2WYGB 4G1MB 3IITB 4NA9L 2VWLL 1YGCL 3EGFA 5IKVA 1Q4GA 2FLRL 3TBDA 3ZYIB 4JZFL 2JKHL 1ATDA 4A7IA 1HRFA 4X8VL 2EI8B 2BOKL 3GCXE 2M74A 4ZAEB 4Y7BB 5EGMB 3U73A 1K37A 4CUDA 5JVYA 1DIYA 2J38B 2EI7B 5IKQA 4BTIA 6COXA 2P3FL 4X8SL 3NTGA 1KIGL 4YT7L 5IKRA 4BDXA 4MMZB 1EMOA 5KN5C 2KV4A 2XBVL 2XBYL 3QMOA 1F0RB 1EPJA 3KK6A 2I9AA 1N1IA 2P3TA 1B9WA 2W2ME 3HS7A 1NFXB 3LIWB 3N8WA 3TGFA 1LMJA 1COUA 1FE2A 4CUEA 2D1JB 2RHPA 3HS5A 4JZDL 4RRZA 3ZYJB 1PFXL 1URKA 3U7UG 1IQGL 2AYLA 4Y71B 1CQEA 1W7XL 2P93L 3P5BL 1EPHA 2FLGA 1NFWB 2VWNL 1IQEL 3K9XA 2VJ3A 1HREA 1XKAL 4LMFA 1CX2A 4X8TL 4E1GA 2UWOB 3MQEA 4ZXXL 3HO5A 1FAXL 4Y79B 2TGFA 1ATEA 2P94L 4RRWA 2VVVL 1NZIA 5F19A 2J4IB 2VVUL 2WPME 2Y5GL 1CCVA 4YZUB 1JBUL 2XBWL 1IJQA 1TLEA 1HT8A 3HO3A 4MMXB 2BZ6L 1G1SA 3M36L 2KB9A 1HJ7A 3TK6B 3LTGD 1KSNB 3R05A 1HAEA 2I9BA 2WPIE 2BQWA 1WHEA 1JL9A 5JBAE 3F6UL 4Y76B 3GISX 2VVCK 5JVZA 1IGXA 4RRYA 2PHBB
chains in the Genus database with same CATH superfamily
3BT1A 1IP0A 1DX5I 1KLJL 2VRSA 3PGHA 1EGFA 1PTHA 4C16A 2Y38A 1IGZA 5CKQA 2KL7A 3LTFB 2Y81B 5JB9E 1ZAQA 1LPZA 4ZXYL 1NFYB 1IQIL 1EMNA 2UWLB 3CS7L 2BT8A 3HS6A 4BTUA 1YO8A 1Z6EL 1PXXA 1U67A 1DQBA 1IQKL 1J9CL 2Y5FL 4NGAL 5L2ZL 4CSYA 1EPIA 2W2OE 4CUFA 3CENL 4RS0A 3LAQA 1GK5A 4LORA 1U8CB 2J94B 2PUQL 1YUGA 4Z6AL 1HZ8A 1F0SB 4ZHAB 3CA7A 1EQGA 3SOQA 1LK9A 5JB8E 1HT5A 4MMYB 2WFXB 5L2YL 2WPLE 1FF7A 1G1TA 1UZQA 4O02B 3LC5B 3V65B 4FM5A 2MHPA 3ASIA 1BF9A 1RFNB 3N8YB 2XC5L 5FDQA 1OB1C 3LN0A 2P95L 2P3UA 2DDUA 4RUTA 1EQHA 3SOVA 3M37L 3Q3KB 2UWPB 3BT2A 2WYJB 2W3KB 1Z6CA 5JBBE 1IQLL 3FCSB 1UZPA 1L3YA 1EAIC 1DDXA 1V1HA 3V64C 2XBXL 1WU1B 1AUTL 1LPKA 1G1RA 2Y80B 2Q1JB 2OYEP 2XC4L 2BOXA 3KCGL 4PH9A 2YGPA 1ATAA 3LN1A 3HO4A 3POYA 1P9JA 2YGQA 2H9EL 4D0FA 4TGFA 1WHFA 2BOHA 1MQ6L 2PR3B 4RRXA 1ADXA 4RRYA 2WPJE 2RA0L 1X7AL 1FJSL 4JZEL 4ISHL 1FAKL 2K2TA 5CKNA 2W26B 1XDTR 2B7DL 3OLTA 1FSBA 4NG9L 1L5GB 2RNLA 1UZKA 4O1ZA 1IQFL 1IVOC 1N7DA 3BPSE 2P28B 2YGOA 1LPGA 2W3IB 3RR3A 1HX2A 2JJLA 2BOUA 1K36A 1EZQB 3TK5B 2K2SB 1IQNL 4XBMA 3N8XA 4A94C 4AQTA 1TOZA 1LQDA 1ATBA 3N8WB 2Y5HL 2OYUP 2WPKE 1G1QA 2ADXA 2BSFA 2F9BL 2W2NE 1MQ5L 3SW2A 2WG4B 1V3XB 5CISA 1IOEL 1MOXC 2VWOL 1APOA 4ISIL 1UZJA 5I46L 1W8BL 1I0UA 3FBYA 1HCGB 5JBCE 2FLBL 1P0SL 4BXWA 5F1AA 2MGRA 3H5CB 1KLIL 4Z0KB 2G00L 1EPGA 4BDWA 2J34B 3GCWE 4M10A 3S6XA 3KL6B 5E8DA 2BMGA 2P16L 3C9AC 1NQLB 2BO2A 4XLWA 1CVWL 1PGEA 1QFKL 2VH6B 1G2MB 4COXA 3FFGL 5K0HB 2Y7ZB 3KQEL 4GU3A 3OLUA 1F7MA 1NT0A 4BXSA 1G2LB 4ZH8B 5IKTA 2WZPP 1APQA 2W2PE 2VWMK 5KIRA 5L30L 1EBVA 2BQ6A 2MGPA 1CVUA 3KQDL 1A3PA 3TH3L 5CKMA 1M1XB 2FZZL 2HOXA 3N8ZA 4JYVL 3NT1A 4X8UL 2WPHE 2W86A 2KNIA 2J2UB 3ENSA 1IQJL 2CJIB 4BTTA 3NJPC 3IJEB 1CEJA 1YUFA 1C5MF 4OTJA 3KRKA 3LC3B 3F1SB 4Y6DB 3TZIA 3NTBA 4YT6L 4OTYA 2BQ7A 5COXA 2NPRA 2GD4A 2W2QE 2WFTA 3HPTA 1JV2B 1HAFA 3KQCL 1CCFA 1YUKB 4M11A 2XC0L 3ZYGA 1TPGA 1XKBA 2VH0B 3MDLA 3N8YA 4Z0LA 1IQML 2Y7XB 1NPEB 1IOXA 3Q7DA 3N8VA 1KLOA 4D0EA 1SZBA 1O5DL 2P26A 1F7EA 3KQBL 3ELAL 4XL1A 3SOBB 4Y7AB 1PRHA 1NFUB 2EI6B 2H9EC 2P3FN 2Y82B 3DEMA 1XFEA 4D90A 2J95B 2FD6A 1IQHL 1DVAL 3QH0A 3CFWA 4JYUL 1FFMA 2WG3C 3QCWA 5JW1A 2WYGB 4G1MB 3IITB 4NA9L 2VWLL 1YGCL 3EGFA 5IKVA 1Q4GA 2FLRL 3TBDA 3ZYIB 4JZFL 2JKHL 1ATDA 4A7IA 2BT7A 1HRFA 4X8VL 2EI8B 2BOKL 3GCXE 1KKEA 2M74A 4ZAEB 4Y7BB 5EGMB 3U73A 1K37A 4CUDA 5JVYA 1DIYA 2J38B 2EI7B 5IKQA 4BTIA 6COXA 2P3FL 4X8SL 3NTGA 1KIGL 4YT7L 1QIUA 5IKRA 4BDXA 1LMMA 4MMZB 1EMOA 4GU4A 5KN5C 2KV4A 2XBVL 2XBYL 3QMOA 1F0RB 1EPJA 3KK6A 2I9AA 1N1IA 2P3TA 1B9WA 2W2ME 3HS7A 1NFXB 3LIWB 3N8WA 3TGFA 1LMJA 1COUA 1FE2A 4CUEA 2D1JB 2RHPA 3HS5A 4JZDL 4RRZA 3ZYJB 1PFXL 1URKA 3U7UG 1IQGL 2AYLA 4Y71B 1CQEA 1W7XL 2P93L 3P5BL 1EPHA 2FLGA 1NFWB 2VWNL 1IQEL 3K9XA 2VJ3A 1HREA 1XKAL 4LMFA 1CX2A 4X8TL 1V1IA 4E1GA 2UWOB 3MQEA 4ZXXL 3HO5A 1FAXL 4Y79B 2TGFA 1ATEA 2P94L 4RRWA 2VVVL 1NZIA 5F19A 2J4IB 2VVUL 2WPME 2Y5GL 1CCVA 4YZUB 1JBUL 2XBWL 1IJQA 1TLEA 1HT8A 3HO3A 4MMXB 2BZ6L 1G1SA 3M36L 2KB9A 1HJ7A 3TK6B 3LTGD 1KSNB 3R05A 1HAEA 2I9BA 2WPIE 2BQWA 1WHEA 1JL9A 5JBAE 3F6UL 4Y76B 3GISX 2VVCK 5JVZA 1IGXA 2HORA 2PHBB
chains in the Genus database with same CATH topology
3BT1A 1IP0A 1DX5I 1KLJL 3PGHA 1EGFA 1PTHA 4C16A 2Y38A 1IGZA 5CKQA 2KL7A 3LTFB 2Y81B 5JB9E 1ZAQA 1LPZA 4ZXYL 1NFYB 1IQIL 1EMNA 2UWLB 3CS7L 3HS6A 4BTUA 1YO8A 1Z6EL 1PXXA 1U67A 1DQBA 1IQKL 1J9CL 2Y5FL 4NGAL 5L2ZL 4CSYA 1EPIA 2W2OE 4CUFA 3CENL 4RS0A 3LAQA 1GK5A 4LORA 1U8CB 2J94B 2PUQL 1YUGA 4Z6AL 1HZ8A 1F0SB 4ZHAB 3CA7A 1EQGA 3SOQA 5JB8E 1HT5A 4MMYB 2WFXB 5L2YL 2WPLE 1FF7A 1G1TA 1UZQA 4O02B 3LC5B 3V65B 4FM5A 2MHPA 3ASIA 1BF9A 1RFNB 3N8YB 2XC5L 5FDQA 1OB1C 3LN0A 2P95L 2P3UA 2DDUA 4RUTA 1EQHA 3SOVA 3M37L 3Q3KB 2UWPB 3BT2A 2WYJB 2W3KB 1Z6CA 5JBBE 1IQLL 3FCSB 1UZPA 1L3YA 1EAIC 1DDXA 3V64C 2XBXL 1WU1B 1AUTL 1LPKA 1G1RA 2Y80B 2Q1JB 2OYEP 2XC4L 2BOXA 3KCGL 4PH9A 2YGPA 1ATAA 3LN1A 3HO4A 3POYA 1P9JA 2YGQA 2H9EL 4D0FA 4TGFA 1WHFA 2BOHA 1MQ6L 2PR3B 4RRXA 1ADXA 2WPJE 2RA0L 1X7AL 1FJSL 4JZEL 4ISHL 1FAKL 2K2TA 5CKNA 2W26B 1XDTR 2B7DL 3OLTA 1FSBA 4NG9L 1L5GB 2RNLA 1UZKA 4O1ZA 1IQFL 1IVOC 1N7DA 3BPSE 2P28B 2YGOA 1LPGA 2W3IB 3RR3A 1HX2A 2BOUA 1K36A 1EZQB 3TK5B 2K2SB 1IQNL 4XBMA 3N8XA 4A94C 4AQTA 1TOZA 1LQDA 1ATBA 3N8WB 2Y5HL 2OYUP 2WPKE 1G1QA 2ADXA 2F9BL 2W2NE 1MQ5L 3SW2A 2WG4B 1V3XB 5CISA 1IOEL 1MOXC 2VWOL 1APOA 4ISIL 1UZJA 5I46L 1W8BL 1I0UA 3FBYA 1HCGB 5JBCE 2FLBL 1P0SL 4BXWA 5F1AA 2MGRA 3H5CB 1KLIL 4Z0KB 2G00L 1EPGA 4BDWA 2J34B 3GCWE 4M10A 3S6XA 3KL6B 5E8DA 2BMGA 2P16L 3C9AC 1NQLB 2BO2A 4XLWA 1CVWL 1PGEA 1QFKL 2VH6B 1G2MB 4COXA 3FFGL 5K0HB 2Y7ZB 3KQEL 3OLUA 1F7MA 1NT0A 4BXSA 1G2LB 4ZH8B 5IKTA 2WZPP 1APQA 2W2PE 2VWMK 5KIRA 5L30L 1EBVA 2BQ6A 2MGPA 1CVUA 3KQDL 1A3PA 3TH3L 5CKMA 1M1XB 2FZZL 3N8ZA 4JYVL 4X8UL 3NT1A 2WPHE 2W86A 2KNIA 2J2UB 3ENSA 1IQJL 2CJIB 4BTTA 3NJPC 3IJEB 1CEJA 1YUFA 1C5MF 4OTJA 3KRKA 3LC3B 3F1SB 4Y6DB 3TZIA 3NTBA 4YT6L 4OTYA 2BQ7A 5COXA 2NPRA 2GD4A 2W2QE 2WFTA 3HPTA 1JV2B 1HAFA 3KQCL 1CCFA 1YUKB 4M11A 2XC0L 3ZYGA 1TPGA 1XKBA 2VH0B 3MDLA 3N8YA 4Z0LA 1IQML 2Y7XB 1NPEB 1IOXA 3Q7DA 3N8VA 1KLOA 4D0EA 1SZBA 1O5DL 2P26A 1F7EA 3KQBL 3ELAL 4XL1A 3SOBB 4Y7AB 1PRHA 1NFUB 2EI6B 2H9EC 2P3FN 2Y82B 3DEMA 1XFEA 4D90A 2J95B 2FD6A 1IQHL 1DVAL 3QH0A 3CFWA 4JYUL 1FFMA 2WG3C 3QCWA 5JW1A 2WYGB 4G1MB 3IITB 4NA9L 2VWLL 1YGCL 3EGFA 5IKVA 1Q4GA 2FLRL 3TBDA 3ZYIB 4JZFL 2JKHL 1ATDA 4A7IA 1HRFA 4X8VL 2EI8B 2BOKL 3GCXE 2M74A 4ZAEB 4Y7BB 5EGMB 3U73A 1K37A 4CUDA 5JVYA 1DIYA 2J38B 2EI7B 5IKQA 4BTIA 6COXA 2P3FL 4X8SL 3NTGA 1KIGL 4YT7L 5IKRA 4BDXA 1LMMA 4MMZB 1EMOA 5KN5C 2KV4A 2XBVL 2XBYL 3QMOA 1F0RB 1EPJA 3KK6A 2I9AA 1N1IA 2P3TA 1B9WA 2W2ME 3HS7A 1NFXB 3LIWB 3N8WA 3TGFA 1LMJA 1COUA 1FE2A 4CUEA 2D1JB 2RHPA 3HS5A 4JZDL 4RRZA 3ZYJB 1PFXL 1URKA 3U7UG 1IQGL 2AYLA 4Y71B 1CQEA 1W7XL 2P93L 3P5BL 1EPHA 2FLGA 1NFWB 2VWNL 1IQEL 3K9XA 2VJ3A 1HREA 1XKAL 4LMFA 1CX2A 4X8TL 4E1GA 2UWOB 3MQEA 4ZXXL 3HO5A 1FAXL 4Y79B 2TGFA 1ATEA 2P94L 4RRWA 2VVVL 1NZIA 5F19A 2J4IB 2VVUL 2WPME 2Y5GL 1CCVA 4YZUB 1JBUL 2XBWL 1IJQA 1TLEA 1HT8A 3HO3A 4MMXB 2BZ6L 1G1SA 3M36L 2KB9A 1HJ7A 3TK6B 3LTGD 1KSNB 3R05A 1HAEA 2I9BA 2WPIE 2BQWA 1WHEA 1JL9A 5JBAE 3F6UL 4Y76B 3GISX 2VVCK 5JVZA 1IGXA 4RRYA 2PHBB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BT1 A;  1IP0 A;  1DX5 I;  1KLJ L;  3PGH A;  1EGF A;  1PTH A;  4C16 A;  2Y38 A;  1IGZ A;  5CKQ A;  2KL7 A;  3LTF B;  2Y81 B;  5JB9 E;  1ZAQ A;  1LPZ A;  4ZXY L;  1NFY B;  1IQI L;  1EMN A;  2UWL B;  3CS7 L;  3HS6 A;  4BTU A;  1YO8 A;  1Z6E L;  1PXX A;  1U67 A;  1DQB A;  1IQK L;  1J9C L;  2Y5F L;  4NGA L;  5L2Z L;  4CSY A;  1EPI A;  2W2O E;  4CUF A;  3CEN L;  4RS0 A;  3LAQ A;  1GK5 A;  4LOR A;  1U8C B;  2J94 B;  2PUQ L;  1YUG A;  4Z6A L;  1HZ8 A;  1F0S B;  4ZHA B;  3CA7 A;  1EQG A;  3SOQ A;  5JB8 E;  1HT5 A;  4MMY B;  2WFX B;  5L2Y L;  2WPL E;  1FF7 A;  1G1T A;  1UZQ A;  4O02 B;  3LC5 B;  3V65 B;  4FM5 A;  2MHP A;  3ASI A;  1BF9 A;  1RFN B;  3N8Y B;  2XC5 L;  5FDQ A;  1OB1 C;  3LN0 A;  2P95 L;  2P3U A;  2DDU A;  4RUT A;  1EQH A;  3SOV A;  3M37 L;  3Q3K B;  2UWP B;  3BT2 A;  2WYJ B;  2W3K B;  1Z6C A;  5JBB E;  1IQL L;  3FCS B;  1UZP A;  1L3Y A;  1EAI C;  1DDX A;  3V64 C;  2XBX L;  1WU1 B;  1AUT L;  1LPK A;  1G1R A;  2Y80 B;  2Q1J B;  2OYE P;  2XC4 L;  2BOX A;  3KCG L;  4PH9 A;  2YGP A;  1ATA A;  3LN1 A;  3HO4 A;  3POY A;  1P9J A;  2H9E L;  4D0F A;  4TGF A;  1WHF A;  2BOH A;  1MQ6 L;  2PR3 B;  4RRX A;  1ADX A;  2WPJ E;  2RA0 L;  1X7A L;  1FJS L;  4JZE L;  4ISH L;  1FAK L;  2K2T A;  5CKN A;  2W26 B;  1XDT R;  2B7D L;  3OLT A;  1FSB A;  4NG9 L;  1L5G B;  2RNL A;  1UZK A;  4O1Z A;  1IQF L;  1IVO C;  1N7D A;  3BPS E;  2P28 B;  2YGO A;  1LPG A;  2W3I B;  3RR3 A;  1HX2 A;  2BOU A;  1K36 A;  1EZQ B;  3TK5 B;  2K2S B;  1IQN L;  4XBM A;  3N8X A;  4AQT A;  1TOZ A;  1LQD A;  1ATB A;  3N8W B;  2Y5H L;  2OYU P;  2WPK E;  1G1Q A;  2ADX A;  2F9B L;  2W2N E;  1MQ5 L;  3SW2 A;  2WG4 B;  1V3X B;  5CIS A;  1IOE L;  1MOX C;  2VWO L;  1APO A;  4ISI L;  1UZJ A;  5I46 L;  1W8B L;  1I0U A;  3FBY A;  1HCG B;  5JBC E;  2FLB L;  1P0S L;  4BXW A;  5F1A A;  2MGR A;  3H5C B;  1KLI L;  4Z0K B;  2G00 L;  1EPG A;  4BDW A;  2J34 B;  3GCW E;  4M10 A;  3KL6 B;  5E8D A;  2BMG A;  2P16 L;  3C9A C;  1NQL B;  2BO2 A;  4XLW A;  1CVW L;  1PGE A;  1QFK L;  2VH6 B;  1G2M B;  4COX A;  3FFG L;  5K0H B;  2Y7Z B;  3KQE L;  3OLU A;  1F7M A;  1NT0 A;  4BXS A;  1G2L B;  4ZH8 B;  5IKT A;  1APQ A;  2W2P E;  2VWM K;  5KIR A;  5L30 L;  1EBV A;  2BQ6 A;  2MGP A;  1CVU A;  3KQD L;  1A3P A;  3TH3 L;  5CKM A;  1M1X B;  2FZZ L;  3N8Z A;  4JYV L;  4X8U L;  3NT1 A;  2WPH E;  2W86 A;  2J2U B;  3ENS A;  1IQJ L;  2CJI B;  4BTT A;  3NJP C;  3IJE B;  1CEJ A;  1YUF A;  1C5M F;  4OTJ A;  3KRK A;  3LC3 B;  3F1S B;  4Y6D B;  3TZI A;  3NTB A;  4YT6 L;  4OTY A;  2BQ7 A;  5COX A;  2NPR A;  2GD4 A;  2W2Q E;  2WFT A;  3HPT A;  1JV2 B;  1HAF A;  3KQC L;  1CCF A;  1YUK B;  4M11 A;  2XC0 L;  3ZYG A;  1TPG A;  1XKB A;  2VH0 B;  3MDL A;  3N8Y A;  4Z0L A;  1IQM L;  2Y7X B;  1NPE B;  1IOX A;  3Q7D A;  3N8V A;  1KLO A;  4D0E A;  1SZB A;  1O5D L;  2P26 A;  1F7E A;  3KQB L;  3ELA L;  4XL1 A;  3SOB B;  4Y7A B;  1PRH A;  1NFU B;  2EI6 B;  2P3F N;  2Y82 B;  4D90 A;  3DEM A;  1XFE A;  2J95 B;  2FD6 A;  1IQH L;  1DVA L;  3QH0 A;  3CFW A;  4JYU L;  1FFM A;  2WG3 C;  3QCW A;  5JW1 A;  2WYG B;  4G1M B;  3IIT B;  4NA9 L;  2VWL L;  1YGC L;  3EGF A;  5IKV A;  1Q4G A;  2FLR L;  3TBD A;  3ZYI B;  4JZF L;  2JKH L;  1ATD A;  4A7I A;  1HRF A;  4X8V L;  2EI8 B;  2BOK L;  3GCX E;  2M74 A;  4ZAE B;  4Y7B B;  5EGM B;  3U73 A;  1K37 A;  4CUD A;  5JVY A;  1DIY A;  2J38 B;  2EI7 B;  5IKQ A;  4BTI A;  6COX A;  2P3F L;  4X8S L;  3NTG A;  1KIG L;  4YT7 L;  5IKR A;  4BDX A;  4MMZ B;  1EMO A;  5KN5 C;  2KV4 A;  2XBV L;  2XBY L;  3QMO A;  1F0R B;  1EPJ A;  3KK6 A;  2I9A A;  1N1I A;  2P3T A;  1B9W A;  2W2M E;  3HS7 A;  1NFX B;  3LIW B;  3N8W A;  3TGF A;  1LMJ A;  1COU A;  1FE2 A;  4CUE A;  2D1J B;  2RHP A;  3HS5 A;  4JZD L;  4RRZ A;  3ZYJ B;  1PFX L;  1URK A;  3U7U G;  1IQG L;  2AYL A;  4Y71 B;  1CQE A;  1W7X L;  2P93 L;  3P5B L;  1EPH A;  2FLG A;  1NFW B;  2VWN L;  1IQE L;  3K9X A;  2VJ3 A;  1HRE A;  1XKA L;  4LMF A;  1CX2 A;  4X8T L;  4E1G A;  2UWO B;  3MQE A;  4ZXX L;  3HO5 A;  1FAX L;  4Y79 B;  2TGF A;  1ATE A;  2P94 L;  4RRW A;  2VVV L;  1NZI A;  5F19 A;  2J4I B;  2VVU L;  2WPM E;  2Y5G L;  1CCV A;  4YZU B;  1JBU L;  2XBW L;  1IJQ A;  1TLE A;  1HT8 A;  3HO3 A;  4MMX B;  2BZ6 L;  1G1S A;  3M36 L;  2KB9 A;  1HJ7 A;  3TK6 B;  3LTG D;  1KSN B;  3R05 A;  1HAE A;  2I9B A;  2WPI E;  2BQW A;  1WHE A;  1JL9 A;  5JBA E;  3F6U L;  4Y76 B;  3GIS X;  2VVC K;  5JVZ A;  1IGX A;  4RRY A;  2PHB B; 
#chains in the Genus database with same CATH topology
 3BT1 A;  1IP0 A;  1DX5 I;  1KLJ L;  2VRS A;  3PGH A;  1EGF A;  1PTH A;  4C16 A;  2Y38 A;  1IGZ A;  5CKQ A;  2KL7 A;  3LTF B;  2Y81 B;  5JB9 E;  1ZAQ A;  1LPZ A;  4ZXY L;  1NFY B;  1IQI L;  1EMN A;  2UWL B;  3CS7 L;  2BT8 A;  3HS6 A;  4BTU A;  1YO8 A;  1Z6E L;  1PXX A;  1U67 A;  1DQB A;  1IQK L;  1J9C L;  2Y5F L;  4NGA L;  5L2Z L;  4CSY A;  1EPI A;  2W2O E;  4CUF A;  3CEN L;  4RS0 A;  3LAQ A;  1GK5 A;  4LOR A;  1U8C B;  2J94 B;  2PUQ L;  1YUG A;  4Z6A L;  1HZ8 A;  1F0S B;  4ZHA B;  3CA7 A;  1EQG A;  3SOQ A;  1LK9 A;  5JB8 E;  1HT5 A;  4MMY B;  2WFX B;  5L2Y L;  2WPL E;  1FF7 A;  1G1T A;  1UZQ A;  4O02 B;  3LC5 B;  3V65 B;  4FM5 A;  2MHP A;  3ASI A;  1BF9 A;  1RFN B;  3N8Y B;  2XC5 L;  5FDQ A;  1OB1 C;  3LN0 A;  2P95 L;  2P3U A;  2DDU A;  4RUT A;  1EQH A;  3SOV A;  3M37 L;  3Q3K B;  2UWP B;  3BT2 A;  2WYJ B;  2W3K B;  1Z6C A;  5JBB E;  1IQL L;  3FCS B;  1UZP A;  1L3Y A;  1EAI C;  1DDX A;  1V1H A;  3V64 C;  2XBX L;  1WU1 B;  1AUT L;  1LPK A;  1G1R A;  2Y80 B;  2Q1J B;  2OYE P;  2XC4 L;  2BOX A;  3KCG L;  4PH9 A;  2YGP A;  1ATA A;  3LN1 A;  3HO4 A;  3POY A;  1P9J A;  2YGQ A;  2H9E L;  4D0F A;  4TGF A;  1WHF A;  2BOH A;  1MQ6 L;  2PR3 B;  4RRX A;  1ADX A;  4RRY A;  2WPJ E;  2RA0 L;  1X7A L;  1FJS L;  4JZE L;  4ISH L;  1FAK L;  2K2T A;  5CKN A;  2W26 B;  1XDT R;  2B7D L;  3OLT A;  1FSB A;  4NG9 L;  1L5G B;  2RNL A;  1UZK A;  4O1Z A;  1IQF L;  1IVO C;  1N7D A;  3BPS E;  2P28 B;  2YGO A;  1LPG A;  2W3I B;  3RR3 A;  1HX2 A;  2JJL A;  2BOU A;  1K36 A;  1EZQ B;  3TK5 B;  2K2S B;  1IQN L;  4XBM A;  3N8X A;  4A94 C;  4AQT A;  1TOZ A;  1LQD A;  1ATB A;  3N8W B;  2Y5H L;  2OYU P;  2WPK E;  1G1Q A;  2ADX A;  2BSF A;  2F9B L;  2W2N E;  1MQ5 L;  3SW2 A;  2WG4 B;  1V3X B;  5CIS A;  1IOE L;  1MOX C;  2VWO L;  1APO A;  4ISI L;  1UZJ A;  5I46 L;  1W8B L;  1I0U A;  3FBY A;  1HCG B;  5JBC E;  2FLB L;  1P0S L;  4BXW A;  5F1A A;  2MGR A;  3H5C B;  1KLI L;  4Z0K B;  2G00 L;  1EPG A;  4BDW A;  2J34 B;  3GCW E;  4M10 A;  3S6X A;  3KL6 B;  5E8D A;  2BMG A;  2P16 L;  3C9A C;  1NQL B;  2BO2 A;  4XLW A;  1CVW L;  1PGE A;  1QFK L;  2VH6 B;  1G2M B;  4COX A;  3FFG L;  5K0H B;  2Y7Z B;  3KQE L;  4GU3 A;  3OLU A;  1F7M A;  1NT0 A;  4BXS A;  1G2L B;  4ZH8 B;  5IKT A;  2WZP P;  1APQ A;  2W2P E;  2VWM K;  5KIR A;  5L30 L;  1EBV A;  2BQ6 A;  2MGP A;  1CVU A;  3KQD L;  1A3P A;  3TH3 L;  5CKM A;  1M1X B;  2FZZ L;  2HOX A;  3N8Z A;  4JYV L;  3NT1 A;  4X8U L;  2WPH E;  2W86 A;  2KNI A;  2J2U B;  3ENS A;  1IQJ L;  2CJI B;  4BTT A;  3NJP C;  3IJE B;  1CEJ A;  1YUF A;  1C5M F;  4OTJ A;  3KRK A;  3LC3 B;  3F1S B;  4Y6D B;  3TZI A;  3NTB A;  4YT6 L;  4OTY A;  2BQ7 A;  5COX A;  2NPR A;  2GD4 A;  2W2Q E;  2WFT A;  3HPT A;  1JV2 B;  1HAF A;  3KQC L;  1CCF A;  1YUK B;  4M11 A;  2XC0 L;  3ZYG A;  1TPG A;  1XKB A;  2VH0 B;  3MDL A;  3N8Y A;  4Z0L A;  1IQM L;  2Y7X B;  1NPE B;  1IOX A;  3Q7D A;  3N8V A;  1KLO A;  4D0E A;  1SZB A;  1O5D L;  2P26 A;  1F7E A;  3KQB L;  3ELA L;  4XL1 A;  3SOB B;  4Y7A B;  1PRH A;  1NFU B;  2EI6 B;  2H9E C;  2P3F N;  2Y82 B;  3DEM A;  1XFE A;  4D90 A;  2J95 B;  2FD6 A;  1IQH L;  1DVA L;  3QH0 A;  3CFW A;  4JYU L;  1FFM A;  2WG3 C;  3QCW A;  5JW1 A;  2WYG B;  4G1M B;  3IIT B;  4NA9 L;  2VWL L;  1YGC L;  3EGF A;  5IKV A;  1Q4G A;  2FLR L;  3TBD A;  3ZYI B;  4JZF L;  2JKH L;  1ATD A;  4A7I A;  2BT7 A;  1HRF A;  4X8V L;  2EI8 B;  2BOK L;  3GCX E;  1KKE A;  2M74 A;  4ZAE B;  4Y7B B;  5EGM B;  3U73 A;  1K37 A;  4CUD A;  5JVY A;  1DIY A;  2J38 B;  2EI7 B;  5IKQ A;  4BTI A;  6COX A;  2P3F L;  4X8S L;  3NTG A;  1KIG L;  4YT7 L;  1QIU A;  5IKR A;  4BDX A;  1LMM A;  4MMZ B;  1EMO A;  4GU4 A;  5KN5 C;  2KV4 A;  2XBV L;  2XBY L;  3QMO A;  1F0R B;  1EPJ A;  3KK6 A;  2I9A A;  1N1I A;  2P3T A;  1B9W A;  2W2M E;  3HS7 A;  1NFX B;  3LIW B;  3N8W A;  3TGF A;  1LMJ A;  1COU A;  1FE2 A;  4CUE A;  2D1J B;  2RHP A;  3HS5 A;  4JZD L;  4RRZ A;  3ZYJ B;  1PFX L;  1URK A;  3U7U G;  1IQG L;  2AYL A;  4Y71 B;  1CQE A;  1W7X L;  2P93 L;  3P5B L;  1EPH A;  2FLG A;  1NFW B;  2VWN L;  1IQE L;  3K9X A;  2VJ3 A;  1HRE A;  1XKA L;  4LMF A;  1CX2 A;  4X8T L;  1V1I A;  4E1G A;  2UWO B;  3MQE A;  4ZXX L;  3HO5 A;  1FAX L;  4Y79 B;  2TGF A;  1ATE A;  2P94 L;  4RRW A;  2VVV L;  1NZI A;  5F19 A;  2J4I B;  2VVU L;  2WPM E;  2Y5G L;  1CCV A;  4YZU B;  1JBU L;  2XBW L;  1IJQ A;  1TLE A;  1HT8 A;  3HO3 A;  4MMX B;  2BZ6 L;  1G1S A;  3M36 L;  2KB9 A;  1HJ7 A;  3TK6 B;  3LTG D;  1KSN B;  3R05 A;  1HAE A;  2I9B A;  2WPI E;  2BQW A;  1WHE A;  1JL9 A;  5JBA E;  3F6U L;  4Y76 B;  3GIS X;  2VVC K;  5JVZ A;  1IGX A;  2HOR A;  2PHB B; 
#chains in the Genus database with same CATH homology
 3BT1 A;  1IP0 A;  1DX5 I;  1KLJ L;  3PGH A;  1EGF A;  1PTH A;  4C16 A;  2Y38 A;  1IGZ A;  5CKQ A;  2KL7 A;  3LTF B;  2Y81 B;  5JB9 E;  1ZAQ A;  1LPZ A;  4ZXY L;  1NFY B;  1IQI L;  1EMN A;  2UWL B;  3CS7 L;  3HS6 A;  4BTU A;  1YO8 A;  1Z6E L;  1PXX A;  1U67 A;  1DQB A;  1IQK L;  1J9C L;  2Y5F L;  4NGA L;  5L2Z L;  4CSY A;  1EPI A;  2W2O E;  4CUF A;  3CEN L;  4RS0 A;  3LAQ A;  1GK5 A;  4LOR A;  1U8C B;  2J94 B;  2PUQ L;  1YUG A;  4Z6A L;  1HZ8 A;  1F0S B;  4ZHA B;  3CA7 A;  1EQG A;  3SOQ A;  5JB8 E;  1HT5 A;  4MMY B;  2WFX B;  5L2Y L;  2WPL E;  1FF7 A;  1G1T A;  1UZQ A;  4O02 B;  3LC5 B;  3V65 B;  4FM5 A;  2MHP A;  3ASI A;  1BF9 A;  1RFN B;  3N8Y B;  2XC5 L;  5FDQ A;  1OB1 C;  3LN0 A;  2P95 L;  2P3U A;  2DDU A;  4RUT A;  1EQH A;  3SOV A;  3M37 L;  3Q3K B;  2UWP B;  3BT2 A;  2WYJ B;  2W3K B;  1Z6C A;  5JBB E;  1IQL L;  3FCS B;  1UZP A;  1L3Y A;  1EAI C;  1DDX A;  3V64 C;  2XBX L;  1WU1 B;  1AUT L;  1LPK A;  1G1R A;  2Y80 B;  2Q1J B;  2OYE P;  2XC4 L;  2BOX A;  3KCG L;  4PH9 A;  2YGP A;  1ATA A;  3LN1 A;  3HO4 A;  3POY A;  1P9J A;  2YGQ A;  2H9E L;  4D0F A;  4TGF A;  1WHF A;  2BOH A;  1MQ6 L;  2PR3 B;  4RRX A;  1ADX A;  2WPJ E;  2RA0 L;  1X7A L;  1FJS L;  4JZE L;  4ISH L;  1FAK L;  2K2T A;  5CKN A;  2W26 B;  1XDT R;  2B7D L;  3OLT A;  1FSB A;  4NG9 L;  1L5G B;  2RNL A;  1UZK A;  4O1Z A;  1IQF L;  1IVO C;  1N7D A;  3BPS E;  2P28 B;  2YGO A;  1LPG A;  2W3I B;  3RR3 A;  1HX2 A;  2BOU A;  1K36 A;  1EZQ B;  3TK5 B;  2K2S B;  1IQN L;  4XBM A;  3N8X A;  4A94 C;  4AQT A;  1TOZ A;  1LQD A;  1ATB A;  3N8W B;  2Y5H L;  2OYU P;  2WPK E;  1G1Q A;  2ADX A;  2F9B L;  2W2N E;  1MQ5 L;  3SW2 A;  2WG4 B;  1V3X B;  5CIS A;  1IOE L;  1MOX C;  2VWO L;  1APO A;  4ISI L;  1UZJ A;  5I46 L;  1W8B L;  1I0U A;  3FBY A;  1HCG B;  5JBC E;  2FLB L;  1P0S L;  4BXW A;  5F1A A;  2MGR A;  3H5C B;  1KLI L;  4Z0K B;  2G00 L;  1EPG A;  4BDW A;  2J34 B;  3GCW E;  4M10 A;  3S6X A;  3KL6 B;  5E8D A;  2BMG A;  2P16 L;  3C9A C;  1NQL B;  2BO2 A;  4XLW A;  1CVW L;  1PGE A;  1QFK L;  2VH6 B;  1G2M B;  4COX A;  3FFG L;  5K0H B;  2Y7Z B;  3KQE L;  3OLU A;  1F7M A;  1NT0 A;  4BXS A;  1G2L B;  4ZH8 B;  5IKT A;  2WZP P;  1APQ A;  2W2P E;  2VWM K;  5KIR A;  5L30 L;  1EBV A;  2BQ6 A;  2MGP A;  1CVU A;  3KQD L;  1A3P A;  3TH3 L;  5CKM A;  1M1X B;  2FZZ L;  3N8Z A;  4JYV L;  4X8U L;  3NT1 A;  2WPH E;  2W86 A;  2KNI A;  2J2U B;  3ENS A;  1IQJ L;  2CJI B;  4BTT A;  3NJP C;  3IJE B;  1CEJ A;  1YUF A;  1C5M F;  4OTJ A;  3KRK A;  3LC3 B;  3F1S B;  4Y6D B;  3TZI A;  3NTB A;  4YT6 L;  4OTY A;  2BQ7 A;  5COX A;  2NPR A;  2GD4 A;  2W2Q E;  2WFT A;  3HPT A;  1JV2 B;  1HAF A;  3KQC L;  1CCF A;  1YUK B;  4M11 A;  2XC0 L;  3ZYG A;  1TPG A;  1XKB A;  2VH0 B;  3MDL A;  3N8Y A;  4Z0L A;  1IQM L;  2Y7X B;  1NPE B;  1IOX A;  3Q7D A;  3N8V A;  1KLO A;  4D0E A;  1SZB A;  1O5D L;  2P26 A;  1F7E A;  3KQB L;  3ELA L;  4XL1 A;  3SOB B;  4Y7A B;  1PRH A;  1NFU B;  2EI6 B;  2H9E C;  2P3F N;  2Y82 B;  3DEM A;  1XFE A;  4D90 A;  2J95 B;  2FD6 A;  1IQH L;  1DVA L;  3QH0 A;  3CFW A;  4JYU L;  1FFM A;  2WG3 C;  3QCW A;  5JW1 A;  2WYG B;  4G1M B;  3IIT B;  4NA9 L;  2VWL L;  1YGC L;  3EGF A;  5IKV A;  1Q4G A;  2FLR L;  3TBD A;  3ZYI B;  4JZF L;  2JKH L;  1ATD A;  4A7I A;  1HRF A;  4X8V L;  2EI8 B;  2BOK L;  3GCX E;  2M74 A;  4ZAE B;  4Y7B B;  5EGM B;  3U73 A;  1K37 A;  4CUD A;  5JVY A;  1DIY A;  2J38 B;  2EI7 B;  5IKQ A;  4BTI A;  6COX A;  2P3F L;  4X8S L;  3NTG A;  1KIG L;  4YT7 L;  5IKR A;  4BDX A;  1LMM A;  4MMZ B;  1EMO A;  5KN5 C;  2KV4 A;  2XBV L;  2XBY L;  3QMO A;  1F0R B;  1EPJ A;  3KK6 A;  2I9A A;  1N1I A;  2P3T A;  1B9W A;  2W2M E;  3HS7 A;  1NFX B;  3LIW B;  3N8W A;  3TGF A;  1LMJ A;  1COU A;  1FE2 A;  4CUE A;  2D1J B;  2RHP A;  3HS5 A;  4JZD L;  4RRZ A;  3ZYJ B;  1PFX L;  1URK A;  3U7U G;  1IQG L;  2AYL A;  4Y71 B;  1CQE A;  1W7X L;  2P93 L;  3P5B L;  1EPH A;  2FLG A;  1NFW B;  2VWN L;  1IQE L;  3K9X A;  2VJ3 A;  1HRE A;  1XKA L;  4LMF A;  1CX2 A;  4X8T L;  4E1G A;  2UWO B;  3MQE A;  4ZXX L;  3HO5 A;  1FAX L;  4Y79 B;  2TGF A;  1ATE A;  2P94 L;  4RRW A;  2VVV L;  1NZI A;  5F19 A;  2J4I B;  2VVU L;  2WPM E;  2Y5G L;  1CCV A;  4YZU B;  1JBU L;  2XBW L;  1IJQ A;  1TLE A;  1HT8 A;  3HO3 A;  4MMX B;  2BZ6 L;  1G1S A;  3M36 L;  2KB9 A;  1HJ7 A;  3TK6 B;  3LTG D;  1KSN B;  3R05 A;  1HAE A;  2I9B A;  2WPI E;  2BQW A;  1WHE A;  1JL9 A;  5JBA E;  3F6U L;  4Y76 B;  3GIS X;  2VVC K;  5JVZ A;  1IGX A;  4RRY A;  2PHB B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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