2Y7XB

The discovery of potent and long-acting oral factor xa inhibitors with tetrahydroisoquinoline and benzazepine p4 motifs
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2011-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00008 EGF EGF-like domain
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2y7xB00
1IJQA 1XKBA 3FFGL 4ZH8B 1HT5A 1U8CB 2P28B 3NT1A 4Y7AB 1L5GB 2P3TA 4ZXXL 2BOUA 3HS6A 2FZZL 4YT7L 4RRXA 1LPKA 4Y7BB 1V3XB 3IITB 3QMOA 2Y38A 1CQEA 2I9AA 4M10A 5CKMA 4CUFA 4BXSA 2VH6B 2P16L 1CCFA 4OTJA 2VWNL 3ASIA 1IP0A 2BQWA 2VJ3A 2Y81B 4D90A 3PGHA 1G2LB 2H9EL 3LN1A 1W7XL 4JYUL 3BT1A 2W86A 5IKTA 3U73A 4BDXA 3KQCL 3TZIA 3C9AC 4ISIL 3V64C 3KQDL 4JZEL 5FDQA 4XBMA 2I9BA 3N8WB 2Y5FL 4ZXYL 3POYA 1NFWB 1ADXA 1ZAQA 1FE2A 1EPJA 1HAFA 2VWOL 1LPZA 1LPGA 4NA9L 3HPTA 4BDWA 1DDXA 2VVUL 3TH3L 5K0HB 1FAKL 1PGEA 2RHPA 3LIWB 1URKA 4COXA 4Z0LA 1XDTR 1FAXL 1PRHA 1KLOA 2OYUP 1EAIC 1EBVA 1N1IA 3TK5B 3IJEB 1HZ8A 1P0SL 1SZBA 2XC4L 3KQBL 2YGPA 5EGMB 4D0FA 1CVWL 3NTGA 2BO2A 2DDUA 3GISX 4BTTA 4O1ZA 2J34B 2GD4A 1B9WA 2W2OE 3ELAL 2KV4A 5KIRA 5JW1A 1APOA 1AUTL 2W26B 2WYJB 3LTFB 2WPIE 2PUQL 2WFTA 1EMOA 1CEJA 1W8BL 2Q1JB 1EQHA 3N8XA 1IQFL 3BT2A 2VH0B 2BQ7A 1YUFA 2VVVL 2W2ME 3QCWA 2BOKL 1IQHL 4CUDA 1IQIL 3CS7L 3KK6A 4JZFL 4NGAL 1PFXL 1EZQB 2B7DL 1EPIA 2WG4B 4RRZA 3SOBB 4BTUA 3Q7DA 2M74A 1NPEB 5IKRA 4BXWA 1Z6CA 3K9XA 3BPSE 1NFYB 3SOVA 1KSNB 3F1SB 1TLEA 1ATDA 1JL9A 4Y71B 3N8YA 2OYEP 5L2YL 4FM5A 2FLBL 5JBBE 2W3IB 1O5DL 2BZ6L 3DEMA 5CKNA 1JBUL 1UZKA 1HAEA 2JKHL 1HREA 1JV2B 1GK5A 3KRKA 1U67A 5KN5C 1WHEA 2XBWL 2KL7A 4JYVL 1IQJL 3CA7A 3HS7A 4RUTA 2VWLL 5IKVA 1G1RA 1PTHA 1J9CL 2FD6A 1IQML 2K2TA 4ZAEB 1G1TA 3HO3A 2ADXA 2WPME 1K37A 1ATEA 1F7MA 3V65B 2UWOB 1IVOC 2J2UB 3KQEL 1DQBA 2PR3B 3ZYJB 4A7IA 1HCGB 1ATBA 2P3UA 1OB1C 3CFWA 1FJSL 4X8TL 1KIGL 1IQGL 2PHBB 1IOXA 3OLUA 4Z0KB 2MGRA 1N7DA 2P95L 1NZIA 4OTYA 1Q4GA 4YT6L 2W2PE 1LMJA 3H5CB 1LQDA 1A3PA 3F6UL 3GCXE 3LC3B 2WFXB 2Y5GL 1MQ5L 3LTGD 4NG9L 1COUA 1HT8A 1K36A 1MOXC 2G00L 3N8WA 1IQLL 4C16A 5F19A 4YZUB 3TBDA 3CENL 4MMXB 1CX2A 2TGFA 2P93L 5F1AA 3N8ZA 4LORA 3LN0A 3MDLA 2Y7ZB 3ZYGA 3P5BL 2CJIB 1IOEL 1UZPA 2BOHA 2W2NE 1YUKB 2WPKE 1WU1B 3TK6B 4ISHL 3N8VA 2WG3C 4O02B 3GCWE 2EI8B 4PH9A 3EGFA 5JB8E 2W3KB 2W2QE 3M37L 1G1SA 1WHFA 1PXXA 2RA0L 3HO5A 1DIYA 5L2ZL 3SW2A 1IQNL 1C5MF 4E1GA 2Y5HL 1IGZA 1QFKL 5E8DA 1DX5I 2BQ6A 5CISA 2J4IB 4M11A 5JBCE 2BMGA 2XC0L 2UWLB 3HS5A 2Y80B 5JVZA 5JBAE 1ATAA 2EI6B 5COXA 4RS0A 1CVUA 3SOQA 4Y76B 1HJ7A 2YGOA 4RRYA 2WYGB 1YO8A 1EPHA 1KLJL 2RNLA 2P3FL 2P94L 3MQEA 1UZJA 2WPJE 2XC5L 3M36L 2XBXL 1XFEA 3KL6B 1I0UA 2K2SB 3FCSB 2VVCK 4Y79B 4MMYB 4Y6DB 5CKQA 3HO4A 1L3YA 2XBYL 1RFNB 1IGXA 3NJPC 5IKQA 4D0EA 2D1JB 2VWMK 1TOZA 4X8UL 3FBYA 4TGFA 2P3FN 1EPGA 1X7AL 1FFMA 4Z6AL 3U7UG 4RRWA 1NT0A 1EQGA 2F9BL 1NFXB 1NFUB 5JB9E 1G2MB 4G1MB 1YGCL 4CSYA 3ZYIB 2NPRA 1FF7A 4XLWA 2XBVL 4X8SL 1DVAL 4ZHAB 2J95B 2J94B 1HX2A 1P9JA 3KCGL 1HRFA 1KLIL 3R05A 5L30L 1EGFA 1EMNA 2WPHE 1UZQA 3TGFA 2J38B 2KB9A 2FLGA 1M1XB 2EI7B 1CCVA 1TPGA 5I46L 3LC5B 1BF9A 2P26A 1APQA 4X8VL 2Y82B 3OLTA 1F7EA 4AQTA 1F0RB 2Y7XB 4XL1A 1MQ6L 1NQLB 2AYLA 3NTBA 2WPLE 3Q3KB 3ENSA 3N8YB 1XKAL 5JVYA 1IQEL 2MHPA 6COXA 1F0SB 4CUEA 2FLRL 1FSBA 2UWPB 1G1QA 2BOXA 4JZDL 1YUGA 4LMFA 1IQKL 1Z6EL 3LAQA 3RR3A 3QH0A 4BTIA 4MMZB 2MGPA
chains in the Genus database with same CATH superfamily
1KKEA 1IJQA 1XKBA 3FFGL 4ZH8B 1HT5A 1U8CB 2P28B 3NT1A 4Y7AB 1L5GB 2P3TA 4ZXXL 2BOUA 3HS6A 2FZZL 4YT7L 4RRXA 1LPKA 4Y7BB 1V3XB 3IITB 3QMOA 2Y38A 1CQEA 2I9AA 4M10A 5CKMA 4CUFA 4BXSA 2VH6B 2P16L 1CCFA 4OTJA 2VWNL 3ASIA 1IP0A 2WZPP 2BQWA 2VJ3A 2Y81B 4D90A 3PGHA 1G2LB 2H9EL 3LN1A 1W7XL 4JYUL 3BT1A 2W86A 5IKTA 3U73A 4BDXA 3KQCL 3TZIA 3C9AC 4ISIL 3V64C 3KQDL 4JZEL 5FDQA 4XBMA 2I9BA 3N8WB 2Y5FL 4ZXYL 3POYA 1NFWB 2BSFA 1ADXA 1ZAQA 1FE2A 1EPJA 1HAFA 2VWOL 1LPZA 1LPGA 4NA9L 3HPTA 4BDWA 1DDXA 2VVUL 3TH3L 5K0HB 1FAKL 1PGEA 2RHPA 3LIWB 1URKA 4COXA 4Z0LA 1XDTR 1FAXL 1PRHA 1KLOA 2OYUP 1EAIC 1EBVA 1N1IA 3TK5B 3IJEB 1HZ8A 1P0SL 1SZBA 2XC4L 3KQBL 2YGPA 5EGMB 4D0FA 1CVWL 3NTGA 2BO2A 2DDUA 3GISX 4BTTA 4O1ZA 2J34B 2GD4A 1B9WA 2W2OE 3ELAL 2KV4A 5KIRA 5JW1A 1APOA 1AUTL 2W26B 2WYJB 3LTFB 2WPIE 2PUQL 2WFTA 1EMOA 1CEJA 1W8BL 2JJLA 2Q1JB 1EQHA 3N8XA 1IQFL 3BT2A 2VH0B 2BQ7A 1YUFA 2VVVL 2W2ME 3QCWA 2BOKL 1IQHL 4CUDA 1IQIL 3CS7L 3KK6A 4JZFL 4NGAL 1PFXL 1EZQB 2B7DL 1EPIA 2WG4B 4RRZA 3SOBB 4BTUA 2BT7A 3Q7DA 2M74A 1NPEB 5IKRA 4BXWA 1Z6CA 3K9XA 3BPSE 1NFYB 3SOVA 1KSNB 3F1SB 1TLEA 1ATDA 1JL9A 4Y71B 3N8YA 2OYEP 5L2YL 4FM5A 2FLBL 5JBBE 2W3IB 1O5DL 2BZ6L 3DEMA 5CKNA 1JBUL 1UZKA 1HAEA 2JKHL 1HREA 1JV2B 1GK5A 3KRKA 1U67A 5KN5C 1WHEA 2XBWL 2KL7A 4JYVL 1IQJL 3CA7A 3HS7A 4RUTA 2VWLL 5IKVA 1G1RA 3S6XA 1PTHA 1J9CL 2FD6A 1IQML 2K2TA 4ZAEB 1G1TA 3HO3A 2BT8A 2ADXA 2WPME 1K37A 1ATEA 1F7MA 3V65B 4A94C 2UWOB 1IVOC 1QIUA 2J2UB 3KQEL 1DQBA 2PR3B 3ZYJB 4A7IA 1HCGB 1ATBA 2P3UA 1OB1C 3CFWA 4GU4A 1FJSL 4X8TL 1KIGL 1IQGL 2PHBB 1IOXA 3OLUA 4Z0KB 2MGRA 1N7DA 2P95L 1NZIA 4OTYA 1Q4GA 4YT6L 2W2PE 1LMJA 3H5CB 1LQDA 1A3PA 3F6UL 3GCXE 3LC3B 2WFXB 2Y5GL 1MQ5L 3LTGD 4NG9L 1COUA 2YGQA 1HT8A 1K36A 1MOXC 2G00L 3N8WA 1IQLL 4C16A 5F19A 4YZUB 3TBDA 3CENL 4MMXB 1CX2A 2TGFA 2P93L 1V1IA 5F1AA 3N8ZA 4LORA 3LN0A 3MDLA 2Y7ZB 3ZYGA 3P5BL 2CJIB 1IOEL 2HOXA 1UZPA 2BOHA 2W2NE 1YUKB 2WPKE 1WU1B 3TK6B 4ISHL 4GU3A 2VRSA 3N8VA 2WG3C 4O02B 3GCWE 2EI8B 4PH9A 3EGFA 5JB8E 2W3KB 2W2QE 3M37L 1G1SA 1WHFA 1PXXA 2RA0L 3HO5A 1DIYA 1V1HA 5L2ZL 3SW2A 1IQNL 1C5MF 4E1GA 2Y5HL 1IGZA 1QFKL 5E8DA 1DX5I 2BQ6A 5CISA 2J4IB 4M11A 5JBCE 2BMGA 2XC0L 2UWLB 3HS5A 2Y80B 5JVZA 5JBAE 1ATAA 2EI6B 5COXA 4RS0A 1CVUA 3SOQA 4Y76B 1HJ7A 2YGOA 4RRYA 2WYGB 1YO8A 1EPHA 1KLJL 2RNLA 2P3FL 2P94L 3MQEA 1UZJA 2WPJE 2XC5L 3M36L 2XBXL 1XFEA 3KL6B 1I0UA 2K2SB 3FCSB 2VVCK 4Y79B 4MMYB 4Y6DB 5CKQA 3HO4A 1L3YA 2XBYL 1RFNB 1IGXA 3NJPC 5IKQA 4D0EA 2D1JB 2VWMK 1TOZA 4X8UL 3FBYA 4TGFA 2P3FN 1EPGA 1LK9A 1FFMA 1X7AL 4Z6AL 3U7UG 4RRWA 1NT0A 1EQGA 2F9BL 1NFXB 1NFUB 5JB9E 1G2MB 4G1MB 1YGCL 4CSYA 2HORA 3ZYIB 2NPRA 1FF7A 4XLWA 2XBVL 4X8SL 1DVAL 4ZHAB 2J95B 2J94B 1HX2A 1P9JA 3KCGL 1HRFA 1KLIL 1LMMA 3R05A 5L30L 1EGFA 1EMNA 2WPHE 1UZQA 3TGFA 2J38B 2KB9A 2FLGA 1M1XB 2EI7B 1CCVA 1TPGA 5I46L 3LC5B 1BF9A 2P26A 1APQA 4X8VL 2Y82B 3OLTA 1F7EA 4AQTA 1F0RB 2Y7XB 4XL1A 1MQ6L 1NQLB 2AYLA 2KNIA 3NTBA 2WPLE 3Q3KB 3ENSA 3N8YB 1XKAL 5JVYA 1IQEL 2MHPA 6COXA 1F0SB 4CUEA 2FLRL 1FSBA 2UWPB 1G1QA 2BOXA 4JZDL 1YUGA 4LMFA 1IQKL 1Z6EL 3LAQA 3RR3A 3QH0A 4BTIA 4MMZB 2MGPA 2H9EC
chains in the Genus database with same CATH topology
1IJQA 1XKBA 3FFGL 4ZH8B 1HT5A 1U8CB 2P28B 3NT1A 4Y7AB 1L5GB 2P3TA 4ZXXL 2BOUA 3HS6A 2FZZL 4YT7L 4RRXA 1LPKA 4Y7BB 1V3XB 3IITB 3QMOA 2Y38A 1CQEA 2I9AA 4M10A 5CKMA 4CUFA 4BXSA 2VH6B 2P16L 1CCFA 4OTJA 2VWNL 3ASIA 1IP0A 2WZPP 2BQWA 2VJ3A 2Y81B 4D90A 3PGHA 1G2LB 2H9EL 3LN1A 1W7XL 4JYUL 3BT1A 2W86A 5IKTA 3U73A 4BDXA 3KQCL 3TZIA 3C9AC 4ISIL 3V64C 3KQDL 4JZEL 5FDQA 4XBMA 2I9BA 3N8WB 2Y5FL 4ZXYL 3POYA 1NFWB 1ADXA 1ZAQA 1FE2A 1EPJA 1HAFA 2VWOL 1LPZA 1LPGA 4NA9L 3HPTA 4BDWA 1DDXA 2VVUL 3TH3L 5K0HB 1FAKL 1PGEA 2RHPA 3LIWB 1URKA 4COXA 4Z0LA 1XDTR 1FAXL 1PRHA 1KLOA 2OYUP 1EAIC 1EBVA 1N1IA 3TK5B 3IJEB 1HZ8A 1P0SL 1SZBA 2XC4L 3KQBL 2YGPA 5EGMB 4D0FA 1CVWL 3NTGA 2BO2A 2DDUA 3GISX 4BTTA 4O1ZA 2J34B 2GD4A 1B9WA 2W2OE 3ELAL 2KV4A 5KIRA 5JW1A 1APOA 1AUTL 2W26B 2WYJB 3LTFB 2WPIE 2PUQL 2WFTA 1EMOA 1CEJA 1W8BL 2Q1JB 1EQHA 3N8XA 1IQFL 3BT2A 2VH0B 2BQ7A 1YUFA 2VVVL 2W2ME 3QCWA 2BOKL 1IQHL 4CUDA 1IQIL 3CS7L 3KK6A 4JZFL 4NGAL 1PFXL 1EZQB 2B7DL 1EPIA 2WG4B 4RRZA 3SOBB 4BTUA 3Q7DA 2M74A 1NPEB 5IKRA 4BXWA 1Z6CA 3K9XA 3BPSE 1NFYB 3SOVA 1KSNB 3F1SB 1TLEA 1ATDA 1JL9A 4Y71B 3N8YA 2OYEP 5L2YL 4FM5A 2FLBL 5JBBE 2W3IB 1O5DL 2BZ6L 3DEMA 5CKNA 1JBUL 1UZKA 1HAEA 2JKHL 1HREA 1JV2B 1GK5A 3KRKA 1U67A 5KN5C 1WHEA 2XBWL 2KL7A 4JYVL 1IQJL 3CA7A 3HS7A 4RUTA 2VWLL 5IKVA 1G1RA 3S6XA 1PTHA 1J9CL 2FD6A 1IQML 2K2TA 4ZAEB 1G1TA 3HO3A 2ADXA 2WPME 1K37A 1ATEA 1F7MA 3V65B 4A94C 2UWOB 1IVOC 2J2UB 3KQEL 1DQBA 2PR3B 3ZYJB 4A7IA 1HCGB 1ATBA 2P3UA 1OB1C 3CFWA 1FJSL 4X8TL 1KIGL 1IQGL 2PHBB 1IOXA 3OLUA 4Z0KB 2MGRA 1N7DA 2P95L 1NZIA 4OTYA 1Q4GA 4YT6L 2W2PE 1LMJA 3H5CB 1LQDA 1A3PA 3F6UL 3GCXE 3LC3B 2WFXB 2Y5GL 1MQ5L 3LTGD 4NG9L 1COUA 2YGQA 1HT8A 1K36A 1MOXC 2G00L 3N8WA 1IQLL 4C16A 5F19A 4YZUB 3TBDA 3CENL 4MMXB 1CX2A 2TGFA 2P93L 5F1AA 3N8ZA 4LORA 3LN0A 3MDLA 2Y7ZB 3ZYGA 3P5BL 2CJIB 1IOEL 1UZPA 2BOHA 2W2NE 1YUKB 2WPKE 1WU1B 3TK6B 4ISHL 3N8VA 2WG3C 4O02B 3GCWE 2EI8B 4PH9A 3EGFA 5JB8E 2W3KB 2W2QE 3M37L 1G1SA 1WHFA 1PXXA 2RA0L 3HO5A 1DIYA 5L2ZL 3SW2A 1IQNL 1C5MF 4E1GA 2Y5HL 1IGZA 1QFKL 5E8DA 1DX5I 2BQ6A 5CISA 2J4IB 4M11A 5JBCE 2BMGA 2XC0L 2UWLB 3HS5A 2Y80B 5JVZA 5JBAE 1ATAA 2EI6B 5COXA 4RS0A 1CVUA 3SOQA 4Y76B 1HJ7A 2YGOA 4RRYA 2WYGB 1YO8A 1EPHA 1KLJL 2RNLA 2P3FL 2P94L 3MQEA 1UZJA 2WPJE 2XC5L 3M36L 2XBXL 1XFEA 3KL6B 1I0UA 2K2SB 3FCSB 2VVCK 4Y79B 4MMYB 4Y6DB 5CKQA 3HO4A 1L3YA 2XBYL 1RFNB 1IGXA 3NJPC 5IKQA 4D0EA 2D1JB 2VWMK 1TOZA 4X8UL 3FBYA 4TGFA 2P3FN 1EPGA 1X7AL 1FFMA 4Z6AL 3U7UG 4RRWA 1NT0A 1EQGA 2F9BL 1NFXB 1NFUB 5JB9E 1G2MB 4G1MB 1YGCL 4CSYA 3ZYIB 2NPRA 1FF7A 4XLWA 2XBVL 4X8SL 1DVAL 4ZHAB 2J95B 2J94B 1HX2A 1P9JA 3KCGL 1HRFA 1KLIL 1LMMA 3R05A 5L30L 1EGFA 1EMNA 2WPHE 1UZQA 3TGFA 2J38B 2KB9A 2FLGA 1M1XB 2EI7B 1CCVA 1TPGA 5I46L 3LC5B 1BF9A 2P26A 1APQA 4X8VL 2Y82B 3OLTA 1F7EA 4AQTA 1F0RB 2Y7XB 4XL1A 1MQ6L 1NQLB 2AYLA 2KNIA 3NTBA 2WPLE 3Q3KB 3ENSA 3N8YB 1XKAL 5JVYA 1IQEL 2MHPA 6COXA 1F0SB 4CUEA 2FLRL 1FSBA 2UWPB 1G1QA 2BOXA 4JZDL 1YUGA 4LMFA 1IQKL 1Z6EL 3LAQA 3RR3A 3QH0A 4BTIA 4MMZB 2MGPA 2H9EC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IJQ A;  1XKB A;  3FFG L;  4ZH8 B;  1HT5 A;  1U8C B;  2P28 B;  3NT1 A;  4Y7A B;  1L5G B;  2P3T A;  4ZXX L;  2BOU A;  3HS6 A;  2FZZ L;  4YT7 L;  4RRX A;  1LPK A;  4Y7B B;  1V3X B;  3IIT B;  3QMO A;  2Y38 A;  1CQE A;  2I9A A;  4M10 A;  5CKM A;  4CUF A;  4BXS A;  2VH6 B;  2P16 L;  1CCF A;  4OTJ A;  2VWN L;  3ASI A;  1IP0 A;  2BQW A;  2VJ3 A;  2Y81 B;  4D90 A;  3PGH A;  1G2L B;  2H9E L;  3LN1 A;  1W7X L;  4JYU L;  3BT1 A;  2W86 A;  5IKT A;  3U73 A;  4BDX A;  3KQC L;  3TZI A;  3C9A C;  4ISI L;  3V64 C;  3KQD L;  4JZE L;  5FDQ A;  4XBM A;  2I9B A;  3N8W B;  2Y5F L;  4ZXY L;  3POY A;  1NFW B;  1ADX A;  1ZAQ A;  1FE2 A;  1EPJ A;  1HAF A;  2VWO L;  1LPZ A;  1LPG A;  4NA9 L;  3HPT A;  4BDW A;  1DDX A;  2VVU L;  3TH3 L;  5K0H B;  1FAK L;  1PGE A;  2RHP A;  3LIW B;  1URK A;  4COX A;  4Z0L A;  1XDT R;  1FAX L;  1PRH A;  1KLO A;  2OYU P;  1EAI C;  1EBV A;  1N1I A;  3TK5 B;  3IJE B;  1HZ8 A;  1P0S L;  1SZB A;  2XC4 L;  3KQB L;  2YGP A;  5EGM B;  4D0F A;  1CVW L;  3NTG A;  2BO2 A;  2DDU A;  3GIS X;  4BTT A;  4O1Z A;  2J34 B;  2GD4 A;  1B9W A;  2W2O E;  3ELA L;  2KV4 A;  5KIR A;  5JW1 A;  1APO A;  1AUT L;  2W26 B;  2WYJ B;  3LTF B;  2WPI E;  2PUQ L;  2WFT A;  1EMO A;  1CEJ A;  1W8B L;  2Q1J B;  1EQH A;  3N8X A;  1IQF L;  3BT2 A;  2VH0 B;  2BQ7 A;  1YUF A;  2VVV L;  2W2M E;  3QCW A;  2BOK L;  1IQH L;  4CUD A;  1IQI L;  3CS7 L;  3KK6 A;  4JZF L;  4NGA L;  1PFX L;  1EZQ B;  2B7D L;  1EPI A;  2WG4 B;  4RRZ A;  3SOB B;  4BTU A;  3Q7D A;  2M74 A;  1NPE B;  5IKR A;  4BXW A;  1Z6C A;  3K9X A;  3BPS E;  1NFY B;  3SOV A;  1KSN B;  3F1S B;  1TLE A;  1ATD A;  1JL9 A;  4Y71 B;  3N8Y A;  2OYE P;  5L2Y L;  4FM5 A;  2FLB L;  5JBB E;  2W3I B;  1O5D L;  2BZ6 L;  3DEM A;  5CKN A;  1JBU L;  1UZK A;  1HAE A;  2JKH L;  1HRE A;  1JV2 B;  1GK5 A;  3KRK A;  1U67 A;  5KN5 C;  1WHE A;  2XBW L;  2KL7 A;  4JYV L;  1IQJ L;  3CA7 A;  3HS7 A;  4RUT A;  2VWL L;  5IKV A;  1G1R A;  1PTH A;  1J9C L;  2FD6 A;  1IQM L;  2K2T A;  4ZAE B;  1G1T A;  3HO3 A;  2ADX A;  2WPM E;  1K37 A;  1ATE A;  1F7M A;  3V65 B;  2UWO B;  1IVO C;  2J2U B;  3KQE L;  1DQB A;  2PR3 B;  3ZYJ B;  4A7I A;  1HCG B;  1ATB A;  2P3U A;  1OB1 C;  3CFW A;  1FJS L;  4X8T L;  1KIG L;  1IQG L;  2PHB B;  1IOX A;  3OLU A;  4Z0K B;  2MGR A;  1N7D A;  2P95 L;  1NZI A;  4OTY A;  1Q4G A;  4YT6 L;  2W2P E;  1LMJ A;  3H5C B;  1LQD A;  1A3P A;  3F6U L;  3GCX E;  3LC3 B;  2WFX B;  2Y5G L;  1MQ5 L;  3LTG D;  4NG9 L;  1COU A;  1HT8 A;  1K36 A;  1MOX C;  2G00 L;  3N8W A;  1IQL L;  4C16 A;  5F19 A;  4YZU B;  3TBD A;  3CEN L;  4MMX B;  1CX2 A;  2TGF A;  2P93 L;  5F1A A;  3N8Z A;  4LOR A;  3LN0 A;  3MDL A;  2Y7Z B;  3ZYG A;  3P5B L;  2CJI B;  1IOE L;  1UZP A;  2BOH A;  2W2N E;  1YUK B;  2WPK E;  1WU1 B;  3TK6 B;  4ISH L;  3N8V A;  2WG3 C;  4O02 B;  3GCW E;  2EI8 B;  4PH9 A;  3EGF A;  5JB8 E;  2W3K B;  2W2Q E;  3M37 L;  1G1S A;  1WHF A;  1PXX A;  2RA0 L;  3HO5 A;  1DIY A;  5L2Z L;  3SW2 A;  1IQN L;  1C5M F;  4E1G A;  2Y5H L;  1IGZ A;  1QFK L;  5E8D A;  1DX5 I;  2BQ6 A;  5CIS A;  2J4I B;  4M11 A;  5JBC E;  2BMG A;  2XC0 L;  2UWL B;  3HS5 A;  2Y80 B;  5JVZ A;  5JBA E;  1ATA A;  2EI6 B;  5COX A;  4RS0 A;  1CVU A;  3SOQ A;  4Y76 B;  1HJ7 A;  2YGO A;  4RRY A;  2WYG B;  1YO8 A;  1EPH A;  1KLJ L;  2RNL A;  2P3F L;  2P94 L;  3MQE A;  1UZJ A;  2WPJ E;  2XC5 L;  3M36 L;  2XBX L;  1XFE A;  3KL6 B;  1I0U A;  2K2S B;  3FCS B;  2VVC K;  4Y79 B;  4MMY B;  4Y6D B;  5CKQ A;  3HO4 A;  1L3Y A;  2XBY L;  1RFN B;  1IGX A;  3NJP C;  5IKQ A;  4D0E A;  2D1J B;  2VWM K;  1TOZ A;  4X8U L;  3FBY A;  4TGF A;  2P3F N;  1EPG A;  1X7A L;  1FFM A;  4Z6A L;  3U7U G;  4RRW A;  1NT0 A;  1EQG A;  2F9B L;  1NFX B;  1NFU B;  5JB9 E;  1G2M B;  4G1M B;  1YGC L;  4CSY A;  3ZYI B;  2NPR A;  1FF7 A;  4XLW A;  2XBV L;  4X8S L;  1DVA L;  4ZHA B;  2J95 B;  2J94 B;  1HX2 A;  1P9J A;  3KCG L;  1HRF A;  1KLI L;  3R05 A;  5L30 L;  1EGF A;  1EMN A;  2WPH E;  1UZQ A;  3TGF A;  2J38 B;  2KB9 A;  2FLG A;  1M1X B;  2EI7 B;  1CCV A;  1TPG A;  5I46 L;  3LC5 B;  1BF9 A;  2P26 A;  1APQ A;  4X8V L;  2Y82 B;  3OLT A;  1F7E A;  4AQT A;  1F0R B;  2Y7X B;  4XL1 A;  1MQ6 L;  1NQL B;  2AYL A;  3NTB A;  2WPL E;  3Q3K B;  3ENS A;  3N8Y B;  1XKA L;  5JVY A;  1IQE L;  2MHP A;  6COX A;  1F0S B;  4CUE A;  2FLR L;  1FSB A;  2UWP B;  1G1Q A;  2BOX A;  4JZD L;  1YUG A;  4LMF A;  1IQK L;  1Z6E L;  3LAQ A;  3RR3 A;  3QH0 A;  4BTI A;  4MMZ B;  2MGP A; 
#chains in the Genus database with same CATH topology
 1KKE A;  1IJQ A;  1XKB A;  3FFG L;  4ZH8 B;  1HT5 A;  1U8C B;  2P28 B;  3NT1 A;  4Y7A B;  1L5G B;  2P3T A;  4ZXX L;  2BOU A;  3HS6 A;  2FZZ L;  4YT7 L;  4RRX A;  1LPK A;  4Y7B B;  1V3X B;  3IIT B;  3QMO A;  2Y38 A;  1CQE A;  2I9A A;  4M10 A;  5CKM A;  4CUF A;  4BXS A;  2VH6 B;  2P16 L;  1CCF A;  4OTJ A;  2VWN L;  3ASI A;  1IP0 A;  2WZP P;  2BQW A;  2VJ3 A;  2Y81 B;  4D90 A;  3PGH A;  1G2L B;  2H9E L;  3LN1 A;  1W7X L;  4JYU L;  3BT1 A;  2W86 A;  5IKT A;  3U73 A;  4BDX A;  3KQC L;  3TZI A;  3C9A C;  4ISI L;  3V64 C;  3KQD L;  4JZE L;  5FDQ A;  4XBM A;  2I9B A;  3N8W B;  2Y5F L;  4ZXY L;  3POY A;  1NFW B;  2BSF A;  1ADX A;  1ZAQ A;  1FE2 A;  1EPJ A;  1HAF A;  2VWO L;  1LPZ A;  1LPG A;  4NA9 L;  3HPT A;  4BDW A;  1DDX A;  2VVU L;  3TH3 L;  5K0H B;  1FAK L;  1PGE A;  2RHP A;  3LIW B;  1URK A;  4COX A;  4Z0L A;  1XDT R;  1FAX L;  1PRH A;  1KLO A;  2OYU P;  1EAI C;  1EBV A;  1N1I A;  3TK5 B;  3IJE B;  1HZ8 A;  1P0S L;  1SZB A;  2XC4 L;  3KQB L;  2YGP A;  5EGM B;  4D0F A;  1CVW L;  3NTG A;  2BO2 A;  2DDU A;  3GIS X;  4BTT A;  4O1Z A;  2J34 B;  2GD4 A;  1B9W A;  2W2O E;  3ELA L;  2KV4 A;  5KIR A;  5JW1 A;  1APO A;  1AUT L;  2W26 B;  2WYJ B;  3LTF B;  2WPI E;  2PUQ L;  2WFT A;  1EMO A;  1CEJ A;  1W8B L;  2JJL A;  2Q1J B;  1EQH A;  3N8X A;  1IQF L;  3BT2 A;  2VH0 B;  2BQ7 A;  1YUF A;  2VVV L;  2W2M E;  3QCW A;  2BOK L;  1IQH L;  4CUD A;  1IQI L;  3CS7 L;  3KK6 A;  4JZF L;  4NGA L;  1PFX L;  1EZQ B;  2B7D L;  1EPI A;  2WG4 B;  4RRZ A;  3SOB B;  4BTU A;  2BT7 A;  3Q7D A;  2M74 A;  1NPE B;  5IKR A;  4BXW A;  1Z6C A;  3K9X A;  3BPS E;  1NFY B;  3SOV A;  1KSN B;  3F1S B;  1TLE A;  1ATD A;  1JL9 A;  4Y71 B;  3N8Y A;  2OYE P;  5L2Y L;  4FM5 A;  2FLB L;  5JBB E;  2W3I B;  1O5D L;  2BZ6 L;  3DEM A;  5CKN A;  1JBU L;  1UZK A;  1HAE A;  2JKH L;  1HRE A;  1JV2 B;  1GK5 A;  3KRK A;  1U67 A;  5KN5 C;  1WHE A;  2XBW L;  2KL7 A;  4JYV L;  1IQJ L;  3CA7 A;  3HS7 A;  4RUT A;  2VWL L;  5IKV A;  1G1R A;  3S6X A;  1PTH A;  1J9C L;  2FD6 A;  1IQM L;  2K2T A;  4ZAE B;  1G1T A;  3HO3 A;  2BT8 A;  2ADX A;  2WPM E;  1K37 A;  1ATE A;  1F7M A;  3V65 B;  4A94 C;  2UWO B;  1IVO C;  1QIU A;  2J2U B;  3KQE L;  1DQB A;  2PR3 B;  3ZYJ B;  4A7I A;  1HCG B;  1ATB A;  2P3U A;  1OB1 C;  3CFW A;  4GU4 A;  1FJS L;  4X8T L;  1KIG L;  1IQG L;  2PHB B;  1IOX A;  3OLU A;  4Z0K B;  2MGR A;  1N7D A;  2P95 L;  1NZI A;  4OTY A;  1Q4G A;  4YT6 L;  2W2P E;  1LMJ A;  3H5C B;  1LQD A;  1A3P A;  3F6U L;  3GCX E;  3LC3 B;  2WFX B;  2Y5G L;  1MQ5 L;  3LTG D;  4NG9 L;  1COU A;  2YGQ A;  1HT8 A;  1K36 A;  1MOX C;  2G00 L;  3N8W A;  1IQL L;  4C16 A;  5F19 A;  4YZU B;  3TBD A;  3CEN L;  4MMX B;  1CX2 A;  2TGF A;  2P93 L;  1V1I A;  5F1A A;  3N8Z A;  4LOR A;  3LN0 A;  3MDL A;  2Y7Z B;  3ZYG A;  3P5B L;  2CJI B;  1IOE L;  2HOX A;  1UZP A;  2BOH A;  2W2N E;  1YUK B;  2WPK E;  1WU1 B;  3TK6 B;  4ISH L;  4GU3 A;  2VRS A;  3N8V A;  2WG3 C;  4O02 B;  3GCW E;  2EI8 B;  4PH9 A;  3EGF A;  5JB8 E;  2W3K B;  2W2Q E;  3M37 L;  1G1S A;  1WHF A;  1PXX A;  2RA0 L;  3HO5 A;  1DIY A;  1V1H A;  5L2Z L;  3SW2 A;  1IQN L;  1C5M F;  4E1G A;  2Y5H L;  1IGZ A;  1QFK L;  5E8D A;  1DX5 I;  2BQ6 A;  5CIS A;  2J4I B;  4M11 A;  5JBC E;  2BMG A;  2XC0 L;  2UWL B;  3HS5 A;  2Y80 B;  5JVZ A;  5JBA E;  1ATA A;  2EI6 B;  5COX A;  4RS0 A;  1CVU A;  3SOQ A;  4Y76 B;  1HJ7 A;  2YGO A;  4RRY A;  2WYG B;  1YO8 A;  1EPH A;  1KLJ L;  2RNL A;  2P3F L;  2P94 L;  3MQE A;  1UZJ A;  2WPJ E;  2XC5 L;  3M36 L;  2XBX L;  1XFE A;  3KL6 B;  1I0U A;  2K2S B;  3FCS B;  2VVC K;  4Y79 B;  4MMY B;  4Y6D B;  5CKQ A;  3HO4 A;  1L3Y A;  2XBY L;  1RFN B;  1IGX A;  3NJP C;  5IKQ A;  4D0E A;  2D1J B;  2VWM K;  1TOZ A;  4X8U L;  3FBY A;  4TGF A;  2P3F N;  1EPG A;  1LK9 A;  1FFM A;  1X7A L;  4Z6A L;  3U7U G;  4RRW A;  1NT0 A;  1EQG A;  2F9B L;  1NFX B;  1NFU B;  5JB9 E;  1G2M B;  4G1M B;  1YGC L;  4CSY A;  2HOR A;  3ZYI B;  2NPR A;  1FF7 A;  4XLW A;  2XBV L;  4X8S L;  1DVA L;  4ZHA B;  2J95 B;  2J94 B;  1HX2 A;  1P9J A;  3KCG L;  1HRF A;  1KLI L;  1LMM A;  3R05 A;  5L30 L;  1EGF A;  1EMN A;  2WPH E;  1UZQ A;  3TGF A;  2J38 B;  2KB9 A;  2FLG A;  1M1X B;  2EI7 B;  1CCV A;  1TPG A;  5I46 L;  3LC5 B;  1BF9 A;  2P26 A;  1APQ A;  4X8V L;  2Y82 B;  3OLT A;  1F7E A;  4AQT A;  1F0R B;  2Y7X B;  4XL1 A;  1MQ6 L;  1NQL B;  2AYL A;  2KNI A;  3NTB A;  2WPL E;  3Q3K B;  3ENS A;  3N8Y B;  1XKA L;  5JVY A;  1IQE L;  2MHP A;  6COX A;  1F0S B;  4CUE A;  2FLR L;  1FSB A;  2UWP B;  1G1Q A;  2BOX A;  4JZD L;  1YUG A;  4LMF A;  1IQK L;  1Z6E L;  3LAQ A;  3RR3 A;  3QH0 A;  4BTI A;  4MMZ B;  2MGP A;  2H9E C; 
#chains in the Genus database with same CATH homology
 1IJQ A;  1XKB A;  3FFG L;  4ZH8 B;  1HT5 A;  1U8C B;  2P28 B;  3NT1 A;  4Y7A B;  1L5G B;  2P3T A;  4ZXX L;  2BOU A;  3HS6 A;  2FZZ L;  4YT7 L;  4RRX A;  1LPK A;  4Y7B B;  1V3X B;  3IIT B;  3QMO A;  2Y38 A;  1CQE A;  2I9A A;  4M10 A;  5CKM A;  4CUF A;  4BXS A;  2VH6 B;  2P16 L;  1CCF A;  4OTJ A;  2VWN L;  3ASI A;  1IP0 A;  2WZP P;  2BQW A;  2VJ3 A;  2Y81 B;  4D90 A;  3PGH A;  1G2L B;  2H9E L;  3LN1 A;  1W7X L;  4JYU L;  3BT1 A;  2W86 A;  5IKT A;  3U73 A;  4BDX A;  3KQC L;  3TZI A;  3C9A C;  4ISI L;  3V64 C;  3KQD L;  4JZE L;  5FDQ A;  4XBM A;  2I9B A;  3N8W B;  2Y5F L;  4ZXY L;  3POY A;  1NFW B;  1ADX A;  1ZAQ A;  1FE2 A;  1EPJ A;  1HAF A;  2VWO L;  1LPZ A;  1LPG A;  4NA9 L;  3HPT A;  4BDW A;  1DDX A;  2VVU L;  3TH3 L;  5K0H B;  1FAK L;  1PGE A;  2RHP A;  3LIW B;  1URK A;  4COX A;  4Z0L A;  1XDT R;  1FAX L;  1PRH A;  1KLO A;  2OYU P;  1EAI C;  1EBV A;  1N1I A;  3TK5 B;  3IJE B;  1HZ8 A;  1P0S L;  1SZB A;  2XC4 L;  3KQB L;  2YGP A;  5EGM B;  4D0F A;  1CVW L;  3NTG A;  2BO2 A;  2DDU A;  3GIS X;  4BTT A;  4O1Z A;  2J34 B;  2GD4 A;  1B9W A;  2W2O E;  3ELA L;  2KV4 A;  5KIR A;  5JW1 A;  1APO A;  1AUT L;  2W26 B;  2WYJ B;  3LTF B;  2WPI E;  2PUQ L;  2WFT A;  1EMO A;  1CEJ A;  1W8B L;  2Q1J B;  1EQH A;  3N8X A;  1IQF L;  3BT2 A;  2VH0 B;  2BQ7 A;  1YUF A;  2VVV L;  2W2M E;  3QCW A;  2BOK L;  1IQH L;  4CUD A;  1IQI L;  3CS7 L;  3KK6 A;  4JZF L;  4NGA L;  1PFX L;  1EZQ B;  2B7D L;  1EPI A;  2WG4 B;  4RRZ A;  3SOB B;  4BTU A;  3Q7D A;  2M74 A;  1NPE B;  5IKR A;  4BXW A;  1Z6C A;  3K9X A;  3BPS E;  1NFY B;  3SOV A;  1KSN B;  3F1S B;  1TLE A;  1ATD A;  1JL9 A;  4Y71 B;  3N8Y A;  2OYE P;  5L2Y L;  4FM5 A;  2FLB L;  5JBB E;  2W3I B;  1O5D L;  2BZ6 L;  3DEM A;  5CKN A;  1JBU L;  1UZK A;  1HAE A;  2JKH L;  1HRE A;  1JV2 B;  1GK5 A;  3KRK A;  1U67 A;  5KN5 C;  1WHE A;  2XBW L;  2KL7 A;  4JYV L;  1IQJ L;  3CA7 A;  3HS7 A;  4RUT A;  2VWL L;  5IKV A;  1G1R A;  3S6X A;  1PTH A;  1J9C L;  2FD6 A;  1IQM L;  2K2T A;  4ZAE B;  1G1T A;  3HO3 A;  2ADX A;  2WPM E;  1K37 A;  1ATE A;  1F7M A;  3V65 B;  4A94 C;  2UWO B;  1IVO C;  2J2U B;  3KQE L;  1DQB A;  2PR3 B;  3ZYJ B;  4A7I A;  1HCG B;  1ATB A;  2P3U A;  1OB1 C;  3CFW A;  1FJS L;  4X8T L;  1KIG L;  1IQG L;  2PHB B;  1IOX A;  3OLU A;  4Z0K B;  2MGR A;  1N7D A;  2P95 L;  1NZI A;  4OTY A;  1Q4G A;  4YT6 L;  2W2P E;  1LMJ A;  3H5C B;  1LQD A;  1A3P A;  3F6U L;  3GCX E;  3LC3 B;  2WFX B;  2Y5G L;  1MQ5 L;  3LTG D;  4NG9 L;  1COU A;  2YGQ A;  1HT8 A;  1K36 A;  1MOX C;  2G00 L;  3N8W A;  1IQL L;  4C16 A;  5F19 A;  4YZU B;  3TBD A;  3CEN L;  4MMX B;  1CX2 A;  2TGF A;  2P93 L;  5F1A A;  3N8Z A;  4LOR A;  3LN0 A;  3MDL A;  2Y7Z B;  3ZYG A;  3P5B L;  2CJI B;  1IOE L;  1UZP A;  2BOH A;  2W2N E;  1YUK B;  2WPK E;  1WU1 B;  3TK6 B;  4ISH L;  3N8V A;  2WG3 C;  4O02 B;  3GCW E;  2EI8 B;  4PH9 A;  3EGF A;  5JB8 E;  2W3K B;  2W2Q E;  3M37 L;  1G1S A;  1WHF A;  1PXX A;  2RA0 L;  3HO5 A;  1DIY A;  5L2Z L;  3SW2 A;  1IQN L;  1C5M F;  4E1G A;  2Y5H L;  1IGZ A;  1QFK L;  5E8D A;  1DX5 I;  2BQ6 A;  5CIS A;  2J4I B;  4M11 A;  5JBC E;  2BMG A;  2XC0 L;  2UWL B;  3HS5 A;  2Y80 B;  5JVZ A;  5JBA E;  1ATA A;  2EI6 B;  5COX A;  4RS0 A;  1CVU A;  3SOQ A;  4Y76 B;  1HJ7 A;  2YGO A;  4RRY A;  2WYG B;  1YO8 A;  1EPH A;  1KLJ L;  2RNL A;  2P3F L;  2P94 L;  3MQE A;  1UZJ A;  2WPJ E;  2XC5 L;  3M36 L;  2XBX L;  1XFE A;  3KL6 B;  1I0U A;  2K2S B;  3FCS B;  2VVC K;  4Y79 B;  4MMY B;  4Y6D B;  5CKQ A;  3HO4 A;  1L3Y A;  2XBY L;  1RFN B;  1IGX A;  3NJP C;  5IKQ A;  4D0E A;  2D1J B;  2VWM K;  1TOZ A;  4X8U L;  3FBY A;  4TGF A;  2P3F N;  1EPG A;  1X7A L;  1FFM A;  4Z6A L;  3U7U G;  4RRW A;  1NT0 A;  1EQG A;  2F9B L;  1NFX B;  1NFU B;  5JB9 E;  1G2M B;  4G1M B;  1YGC L;  4CSY A;  3ZYI B;  2NPR A;  1FF7 A;  4XLW A;  2XBV L;  4X8S L;  1DVA L;  4ZHA B;  2J95 B;  2J94 B;  1HX2 A;  1P9J A;  3KCG L;  1HRF A;  1KLI L;  1LMM A;  3R05 A;  5L30 L;  1EGF A;  1EMN A;  2WPH E;  1UZQ A;  3TGF A;  2J38 B;  2KB9 A;  2FLG A;  1M1X B;  2EI7 B;  1CCV A;  1TPG A;  5I46 L;  3LC5 B;  1BF9 A;  2P26 A;  1APQ A;  4X8V L;  2Y82 B;  3OLT A;  1F7E A;  4AQT A;  1F0R B;  2Y7X B;  4XL1 A;  1MQ6 L;  1NQL B;  2AYL A;  2KNI A;  3NTB A;  2WPL E;  3Q3K B;  3ENS A;  3N8Y B;  1XKA L;  5JVY A;  1IQE L;  2MHP A;  6COX A;  1F0S B;  4CUE A;  2FLR L;  1FSB A;  2UWP B;  1G1Q A;  2BOX A;  4JZD L;  1YUG A;  4LMF A;  1IQK L;  1Z6E L;  3LAQ A;  3RR3 A;  3QH0 A;  4BTI A;  4MMZ B;  2MGP A;  2H9E C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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