2Y7ZB

Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Aminoindane and Phenylpyrrolidine P4 Motifs.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2011-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00008 EGF EGF-like domain
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2y7zB00
1FAXL 3N8WB 1XDTR 4Y7BB 3V65B 1APQA 1EPJA 1FFMA 2GD4A 5E8DA 2XBVL 4Y7AB 1JBUL 2Q1JB 1QFKL 4CUEA 2KB9A 3ELAL 1UZQA 3MQEA 2P3UA 1F7EA 4RRXA 5JBAE 2WPKE 5K0HB 1NFWB 3PGHA 1Z6CA 4RRZA 2P16L 5FDQA 4X8UL 1RFNB 5CKQA 1SZBA 1EQHA 4ISIL 4RRYA 2W86A 3R05A 1IQJL 1PTHA 1FAKL 3EGFA 3SOQA 4RRWA 4BDWA 1W7XL 1P0SL 2J38B 3GCWE 4NGAL 2WYGB 3QH0A 1PXXA 2EI8B 2J94B 3IJEB 3M36L 1HT8A 2VVCK 1HREA 1LPKA 4Y71B 2WG3C 3LC5B 4BXWA 1HX2A 2BQWA 3BPSE 1MOXC 1KLIL 1IQIL 2WPIE 4Z0LA 1I0UA 1EPHA 1EPGA 2YGOA 2FLBL 3HPTA 3KRKA 1GK5A 3LN0A 1CVWL 4ZXXL 4A7IA 1UZPA 3CS7L 1CVUA 1DVAL 4OTYA 2VWOL 2J95B 3OLTA 2RNLA 2BQ7A 1HAEA 1HRFA 2K2SB 3N8YA 5L2ZL 2TGFA 2W3IB 3QMOA 2Y5HL 1FF7A 1IGZA 1LPZA 1FJSL 3IITB 4X8TL 1UZKA 1HZ8A 1PGEA 3ASIA 2YGPA 3SW2A 4BDXA 5JW1A 2W2QE 1IGXA 3MDLA 4BTUA 1NPEB 1IQLL 2PR3B 3TZIA 1HT5A 1CCVA 2P28B 1IQKL 3M37L 2J4IB 4D90A 3BT2A 4D0EA 4BTIA 1F0RB 4Z0KB 1YO8A 5JVYA 2BQ6A 4M11A 1EQGA 2XBWL 3KK6A 4G1MB 1N1IA 4ZH8B 1KLOA 4JYUL 1EPIA 1NFUB 1L5GB 1URKA 1XKBA 3GISX 3LIWB 5IKQA 2WG4B 2XBYL 2UWOB 2Y81B 3KL6B 3FCSB 2WFXB 3N8VA 1IOXA 1LPGA 5JBCE 1LQDA 2FLRL 2PHBB 2MHPA 2J34B 1K36A 1IQNL 1G1QA 4ZAEB 1M1XB 4LORA 1EMNA 1G1TA 1G2LB 2P95L 4X8VL 2Y82B 4MMYB 1HAFA 5CKMA 3OLUA 4C16A 4CSYA 3NTGA 4JZEL 1FSBA 2B7DL 2WPHE 6COXA 5F19A 4YT7L 1CQEA 1DX5I 4Y6DB 3N8ZA 2VH6B 1PRHA 2XC0L 1F0SB 2K2TA 5IKRA 2I9BA 2XC4L 3ZYJB 1LMJA 4RUTA 1EAIC 1XFEA 5EGMB 3N8WA 3HS7A 3NJPC 1DDXA 4ISHL 2CJIB 1IQGL 4FM5A 1BF9A 3NTBA 2BMGA 4YZUB 2P3FL 1DQBA 5JB8E 5IKTA 1WHFA 2WYJB 5COXA 3LC3B 3HO3A 2W2PE 2BOXA 3FFGL 4XL1A 4LMFA 1NFXB 3LTFB 2BZ6L 4O1ZA 2XBXL 4ZHAB 5KN5C 4OTJA 1C5MF 1WHEA 2EI7B 1Z6EL 2VJ3A 2P93L 2VH0B 2ADXA 1O5DL 1AUTL 1IVOC 3F6UL 2VWNL 5CISA 1L3YA 2P94L 1MQ5L 1XKAL 4CUFA 5I46L 3KQDL 3BT1A 2KV4A 1NQLB 3ENSA 3SOVA 4E1GA 1B9WA 5CKNA 1YUGA 1IQML 2P3TA 2Y5FL 2P26A 2KL7A 3TK5B 5JVZA 2BOHA 3Q3KB 2BOKL 1YUKB 2BO2A 2Y7XB 3CA7A 3CFWA 1APOA 1N7DA 1WU1B 3DEMA 2PUQL 3KQCL 5JB9E 2W2ME 2MGRA 1MQ6L 2W2NE 1IOEL 3GCXE 2WPME 1ATBA 1KIGL 4XLWA 3KQBL 1NZIA 3TBDA 1FE2A 4MMZB 4Y76B 1CEJA 3ZYGA 3POYA 3LAQA 1JL9A 3U7UG 2MGPA 3V64C 1DIYA 1P9JA 3HO5A 2BOUA 2FZZL 1HJ7A 3TH3L 1IQHL 2UWPB 4ZXYL 1UZJA 4JZFL 2W2OE 4TGFA 2AYLA 2FD6A 2FLGA 4MMXB 2VVUL 1ATAA 1V3XB 2VWMK 4M10A 3U73A 3ZYIB 2WFTA 4AQTA 3RR3A 4BTTA 3FBYA 4XBMA 5L2YL 4JZDL 1J9CL 4O02B 3KCGL 3N8YB 1HCGB 1X7AL 1ZAQA 4NA9L 1KLJL 3Q7DA 1YGCL 2WPLE 2H9EL 2J2UB 2UWLB 4RS0A 1EZQB 2RHPA 1G1SA 1Q4GA 1NFYB 1TOZA 1IQFL 2JKHL 3H5CB 1IQEL 3F1SB 2DDUA 3P5BL 3LTGD 1JV2B 4PH9A 3NT1A 5L30L 2P3FN 1OB1C 3LN1A 4YT6L 5F1AA 2WPJE 2OYUP 5IKVA 2VWLL 1TPGA 4COXA 1NT0A 4D0FA 1U8CB 2Y5GL 1G2MB 3CENL 2Y80B 5JBBE 3N8XA 3HS6A 4X8SL 2G00L 1CCFA 3C9AC 2D1JB 2Y7ZB 1G1RA 2XC5L 4JYVL 3TK6B 1ADXA 1F7MA 3KQEL 4Y79B 1A3PA 2VVVL 1KSNB 2OYEP 4CUDA 2F9BL 4BXSA 1CX2A 2Y38A 1U67A 2RA0L 1IP0A 1EMOA 1IJQA 1COUA 3SOBB 2NPRA 3TGFA 2I9AA 3K9XA 1PFXL 1ATEA 1K37A 4Z6AL 3HS5A 1W8BL 3HO4A 1ATDA 2M74A 3QCWA 1YUFA 1EBVA 1EGFA 2W3KB 2EI6B 4NG9L 5KIRA 2W26B 1TLEA
chains in the Genus database with same CATH superfamily
1FAXL 3N8WB 1XDTR 4Y7BB 3V65B 1APQA 1EPJA 1FFMA 2GD4A 5E8DA 2XBVL 4Y7AB 1JBUL 2Q1JB 1QFKL 4CUEA 2KB9A 3ELAL 1UZQA 3MQEA 2P3UA 1F7EA 4RRXA 5JBAE 2WPKE 5K0HB 1NFWB 3PGHA 1Z6CA 4RRZA 2P16L 5FDQA 4X8UL 1RFNB 5CKQA 1SZBA 1EQHA 4ISIL 4RRYA 2W86A 3R05A 1IQJL 1PTHA 1FAKL 3EGFA 3SOQA 4RRWA 4BDWA 1W7XL 1P0SL 2J38B 3GCWE 4NGAL 2WYGB 3QH0A 1PXXA 2EI8B 2J94B 3IJEB 3M36L 1HT8A 2VVCK 1HREA 1LPKA 4Y71B 2WG3C 3LC5B 4BXWA 1HX2A 2BQWA 3BPSE 1KKEA 1MOXC 1KLIL 1IQIL 2WPIE 4Z0LA 1I0UA 1EPHA 1EPGA 2YGOA 2FLBL 3HPTA 3KRKA 1GK5A 3LN0A 1CVWL 4ZXXL 4A7IA 1UZPA 3CS7L 1CVUA 1DVAL 4OTYA 2VWOL 2J95B 3OLTA 2RNLA 2BQ7A 1HAEA 1HRFA 2K2SB 3N8YA 5L2ZL 2TGFA 2W3IB 3QMOA 2Y5HL 1FF7A 1IGZA 1LPZA 1FJSL 3IITB 4X8TL 1UZKA 1HZ8A 1PGEA 3ASIA 1LK9A 2YGPA 3SW2A 4BDXA 5JW1A 2W2QE 1IGXA 3MDLA 4GU3A 1LMMA 4BTUA 1NPEB 1IQLL 2PR3B 3TZIA 1HT5A 1CCVA 2P28B 1IQKL 3M37L 2J4IB 4D90A 3BT2A 4D0EA 4BTIA 1F0RB 4Z0KB 1YO8A 5JVYA 2BQ6A 4M11A 1EQGA 2XBWL 3KK6A 4G1MB 1N1IA 4ZH8B 1KLOA 2BT7A 2HORA 4JYUL 1EPIA 1NFUB 2JJLA 1L5GB 1URKA 1XKBA 3GISX 3LIWB 5IKQA 2WG4B 2XBYL 2UWOB 2Y81B 3KL6B 3FCSB 2WFXB 3N8VA 1IOXA 1LPGA 5JBCE 1LQDA 2FLRL 2PHBB 2MHPA 2J34B 1K36A 1IQNL 1G1QA 4ZAEB 1M1XB 4LORA 1EMNA 1G1TA 1G2LB 2P95L 4X8VL 2Y82B 2BSFA 2VRSA 4MMYB 1HAFA 5CKMA 3OLUA 4C16A 4CSYA 3NTGA 4JZEL 1FSBA 2B7DL 2WPHE 6COXA 5F19A 4YT7L 1CQEA 1DX5I 4Y6DB 3N8ZA 2VH6B 1PRHA 2XC0L 1F0SB 2K2TA 5IKRA 2I9BA 2XC4L 3ZYJB 1LMJA 4RUTA 1EAIC 1XFEA 5EGMB 3N8WA 3HS7A 3NJPC 1DDXA 4ISHL 2CJIB 1IQGL 4FM5A 1BF9A 4GU4A 3NTBA 2BMGA 4YZUB 2P3FL 1DQBA 5JB8E 5IKTA 1WHFA 2WYJB 5COXA 3LC3B 3HO3A 2W2PE 2BOXA 3FFGL 4XL1A 4LMFA 1NFXB 3LTFB 2BZ6L 4O1ZA 2XBXL 2HOXA 2YGQA 4ZHAB 5KN5C 4OTJA 1C5MF 1WHEA 2EI7B 1Z6EL 2VJ3A 2P93L 2VH0B 2ADXA 1O5DL 1AUTL 1IVOC 3F6UL 2VWNL 5CISA 1L3YA 2P94L 1MQ5L 1XKAL 4CUFA 5I46L 3KQDL 3BT1A 1QIUA 2KV4A 1NQLB 3ENSA 3SOVA 4E1GA 1B9WA 5CKNA 1YUGA 1IQML 2P3TA 2Y5FL 2P26A 2KL7A 3TK5B 5JVZA 2BOHA 3Q3KB 2BOKL 4A94C 1YUKB 2BO2A 2Y7XB 3CA7A 3CFWA 1APOA 1N7DA 1WU1B 3DEMA 2PUQL 3KQCL 5JB9E 1V1HA 2H9EC 2W2ME 2MGRA 1MQ6L 2W2NE 1IOEL 3GCXE 2WPME 1ATBA 1KIGL 4XLWA 3KQBL 1NZIA 3TBDA 1FE2A 4MMZB 4Y76B 1CEJA 3ZYGA 3POYA 3LAQA 1JL9A 3U7UG 2MGPA 3V64C 1DIYA 1P9JA 3HO5A 2BOUA 2FZZL 1HJ7A 3TH3L 1IQHL 2UWPB 4ZXYL 1UZJA 4JZFL 2W2OE 4TGFA 2AYLA 2FD6A 2FLGA 4MMXB 2VVUL 1ATAA 1V3XB 2VWMK 4M10A 3U73A 3S6XA 3ZYIB 2WFTA 4AQTA 3RR3A 4BTTA 3FBYA 4XBMA 5L2YL 4JZDL 1J9CL 4O02B 3KCGL 3N8YB 1V1IA 1HCGB 1X7AL 1ZAQA 4NA9L 1KLJL 3Q7DA 1YGCL 2WPLE 2H9EL 2J2UB 2UWLB 4RS0A 1EZQB 2RHPA 1G1SA 1Q4GA 1NFYB 1TOZA 1IQFL 2JKHL 3H5CB 1IQEL 3F1SB 2DDUA 3P5BL 3LTGD 1JV2B 4PH9A 3NT1A 5L30L 2P3FN 2KNIA 1OB1C 3LN1A 4YT6L 5F1AA 2WPJE 2OYUP 5IKVA 2VWLL 1TPGA 4COXA 1NT0A 2WZPP 4D0FA 1U8CB 2Y5GL 1G2MB 3CENL 2Y80B 5JBBE 3N8XA 3HS6A 4X8SL 2G00L 1CCFA 3C9AC 2D1JB 2Y7ZB 1G1RA 2BT8A 2XC5L 4JYVL 3TK6B 1ADXA 1F7MA 3KQEL 4Y79B 1A3PA 2VVVL 1KSNB 2OYEP 4CUDA 2F9BL 4BXSA 1CX2A 2Y38A 1U67A 2RA0L 1IP0A 1EMOA 1IJQA 1COUA 3SOBB 2NPRA 3TGFA 2I9AA 3K9XA 1PFXL 1ATEA 1K37A 4Z6AL 3HS5A 1W8BL 3HO4A 1ATDA 2M74A 3QCWA 1YUFA 1EBVA 1EGFA 2W3KB 2EI6B 4NG9L 5KIRA 2W26B 1TLEA
chains in the Genus database with same CATH topology
1FAXL 3N8WB 1XDTR 4Y7BB 3V65B 1APQA 1EPJA 1FFMA 2GD4A 5E8DA 2XBVL 4Y7AB 1JBUL 2Q1JB 1QFKL 4CUEA 2KB9A 3ELAL 1UZQA 3MQEA 2P3UA 1F7EA 4RRXA 5JBAE 2WPKE 5K0HB 1NFWB 3PGHA 1Z6CA 4RRZA 2P16L 5FDQA 4X8UL 1RFNB 5CKQA 1SZBA 1EQHA 4ISIL 4RRYA 2W86A 3R05A 1IQJL 1PTHA 1FAKL 3EGFA 3SOQA 4RRWA 4BDWA 1W7XL 1P0SL 2J38B 3GCWE 4NGAL 2WYGB 3QH0A 1PXXA 2EI8B 2J94B 3IJEB 3M36L 1HT8A 2VVCK 1HREA 1LPKA 4Y71B 2WG3C 3LC5B 4BXWA 1HX2A 2BQWA 3BPSE 1MOXC 1KLIL 1IQIL 2WPIE 4Z0LA 1I0UA 1EPHA 1EPGA 2YGOA 2FLBL 3HPTA 3KRKA 1GK5A 3LN0A 1CVWL 4ZXXL 4A7IA 1UZPA 3CS7L 1CVUA 1DVAL 4OTYA 2VWOL 2J95B 3OLTA 2RNLA 2BQ7A 1HAEA 1HRFA 2K2SB 3N8YA 5L2ZL 2TGFA 2W3IB 3QMOA 2Y5HL 1FF7A 1IGZA 1LPZA 1FJSL 3IITB 4X8TL 1UZKA 1HZ8A 1PGEA 3ASIA 2YGPA 3SW2A 4BDXA 5JW1A 2W2QE 1IGXA 3MDLA 1LMMA 4BTUA 1NPEB 1IQLL 2PR3B 3TZIA 1HT5A 1CCVA 2P28B 1IQKL 3M37L 2J4IB 4D90A 3BT2A 4D0EA 4BTIA 1F0RB 4Z0KB 1YO8A 5JVYA 2BQ6A 4M11A 1EQGA 2XBWL 3KK6A 4G1MB 1N1IA 4ZH8B 1KLOA 4JYUL 1EPIA 1NFUB 1L5GB 1URKA 1XKBA 3GISX 3LIWB 5IKQA 2WG4B 2XBYL 2UWOB 2Y81B 3KL6B 3FCSB 2WFXB 3N8VA 1IOXA 1LPGA 5JBCE 1LQDA 2FLRL 2PHBB 2MHPA 2J34B 1K36A 1IQNL 1G1QA 4ZAEB 1M1XB 4LORA 1EMNA 1G1TA 1G2LB 2P95L 4X8VL 2Y82B 4MMYB 1HAFA 5CKMA 3OLUA 4C16A 4CSYA 3NTGA 4JZEL 1FSBA 2B7DL 2WPHE 6COXA 5F19A 4YT7L 1CQEA 1DX5I 4Y6DB 3N8ZA 2VH6B 1PRHA 2XC0L 1F0SB 2K2TA 5IKRA 2I9BA 2XC4L 3ZYJB 1LMJA 4RUTA 1EAIC 1XFEA 5EGMB 3N8WA 3HS7A 3NJPC 1DDXA 4ISHL 2CJIB 1IQGL 4FM5A 1BF9A 3NTBA 2BMGA 4YZUB 2P3FL 1DQBA 5JB8E 5IKTA 1WHFA 2WYJB 5COXA 3LC3B 3HO3A 2W2PE 2BOXA 3FFGL 4XL1A 4LMFA 1NFXB 3LTFB 2BZ6L 4O1ZA 2XBXL 2YGQA 4ZHAB 5KN5C 4OTJA 1C5MF 1WHEA 2EI7B 1Z6EL 2VJ3A 2P93L 2VH0B 2ADXA 1O5DL 1AUTL 1IVOC 3F6UL 2VWNL 5CISA 1L3YA 2P94L 1MQ5L 1XKAL 4CUFA 5I46L 3KQDL 3BT1A 2KV4A 1NQLB 3ENSA 3SOVA 4E1GA 1B9WA 5CKNA 1YUGA 1IQML 2P3TA 2Y5FL 2P26A 2KL7A 3TK5B 5JVZA 2BOHA 3Q3KB 2BOKL 4A94C 1YUKB 2BO2A 2Y7XB 3CA7A 3CFWA 1APOA 1N7DA 1WU1B 3DEMA 2PUQL 3KQCL 5JB9E 2H9EC 2W2ME 2MGRA 1MQ6L 2W2NE 1IOEL 3GCXE 2WPME 1ATBA 1KIGL 4XLWA 3KQBL 1NZIA 3TBDA 1FE2A 4MMZB 4Y76B 1CEJA 3ZYGA 3POYA 3LAQA 1JL9A 3U7UG 2MGPA 3V64C 1DIYA 1P9JA 3HO5A 2BOUA 2FZZL 1HJ7A 3TH3L 1IQHL 2UWPB 4ZXYL 1UZJA 4JZFL 2W2OE 4TGFA 2AYLA 2FD6A 2FLGA 4MMXB 2VVUL 1ATAA 1V3XB 2VWMK 4M10A 3U73A 3S6XA 3ZYIB 2WFTA 4AQTA 3RR3A 4BTTA 3FBYA 4XBMA 5L2YL 4JZDL 1J9CL 4O02B 3KCGL 3N8YB 1HCGB 1X7AL 1ZAQA 4NA9L 1KLJL 3Q7DA 1YGCL 2WPLE 2H9EL 2J2UB 2UWLB 4RS0A 1EZQB 2RHPA 1G1SA 1Q4GA 1NFYB 1TOZA 1IQFL 2JKHL 3H5CB 1IQEL 3F1SB 2DDUA 3P5BL 3LTGD 1JV2B 4PH9A 3NT1A 5L30L 2P3FN 2KNIA 1OB1C 3LN1A 4YT6L 5F1AA 2WPJE 2OYUP 5IKVA 2VWLL 1TPGA 4COXA 1NT0A 2WZPP 4D0FA 1U8CB 2Y5GL 1G2MB 3CENL 2Y80B 5JBBE 3N8XA 3HS6A 4X8SL 2G00L 1CCFA 3C9AC 2D1JB 2Y7ZB 1G1RA 2XC5L 4JYVL 3TK6B 1ADXA 1F7MA 3KQEL 4Y79B 1A3PA 2VVVL 1KSNB 2OYEP 4CUDA 2F9BL 4BXSA 1CX2A 2Y38A 1U67A 2RA0L 1IP0A 1EMOA 1IJQA 1COUA 3SOBB 2NPRA 3TGFA 2I9AA 3K9XA 1PFXL 1ATEA 1K37A 4Z6AL 3HS5A 1W8BL 3HO4A 1ATDA 2M74A 3QCWA 1YUFA 1EBVA 1EGFA 2W3KB 2EI6B 4NG9L 5KIRA 2W26B 1TLEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FAX L;  3N8W B;  1XDT R;  4Y7B B;  3V65 B;  1APQ A;  1EPJ A;  1FFM A;  2GD4 A;  5E8D A;  2XBV L;  4Y7A B;  1JBU L;  2Q1J B;  1QFK L;  4CUE A;  2KB9 A;  3ELA L;  1UZQ A;  3MQE A;  2P3U A;  1F7E A;  4RRX A;  5JBA E;  2WPK E;  5K0H B;  1NFW B;  3PGH A;  1Z6C A;  4RRZ A;  2P16 L;  5FDQ A;  4X8U L;  1RFN B;  5CKQ A;  1SZB A;  1EQH A;  4ISI L;  4RRY A;  2W86 A;  3R05 A;  1IQJ L;  1PTH A;  1FAK L;  3EGF A;  3SOQ A;  4RRW A;  4BDW A;  1W7X L;  1P0S L;  2J38 B;  3GCW E;  4NGA L;  2WYG B;  3QH0 A;  1PXX A;  2EI8 B;  2J94 B;  3IJE B;  3M36 L;  1HT8 A;  2VVC K;  1HRE A;  1LPK A;  4Y71 B;  2WG3 C;  3LC5 B;  4BXW A;  1HX2 A;  2BQW A;  3BPS E;  1MOX C;  1KLI L;  1IQI L;  2WPI E;  4Z0L A;  1I0U A;  1EPH A;  1EPG A;  2YGO A;  2FLB L;  3HPT A;  3KRK A;  1GK5 A;  3LN0 A;  1CVW L;  4ZXX L;  4A7I A;  1UZP A;  3CS7 L;  1CVU A;  1DVA L;  4OTY A;  2VWO L;  2J95 B;  3OLT A;  2RNL A;  2BQ7 A;  1HAE A;  1HRF A;  2K2S B;  3N8Y A;  5L2Z L;  2TGF A;  2W3I B;  3QMO A;  2Y5H L;  1FF7 A;  1IGZ A;  1LPZ A;  1FJS L;  3IIT B;  4X8T L;  1UZK A;  1HZ8 A;  1PGE A;  3ASI A;  2YGP A;  3SW2 A;  4BDX A;  5JW1 A;  2W2Q E;  1IGX A;  3MDL A;  4BTU A;  1NPE B;  1IQL L;  2PR3 B;  3TZI A;  1HT5 A;  1CCV A;  2P28 B;  1IQK L;  3M37 L;  2J4I B;  4D90 A;  3BT2 A;  4D0E A;  4BTI A;  1F0R B;  4Z0K B;  1YO8 A;  5JVY A;  2BQ6 A;  4M11 A;  1EQG A;  2XBW L;  3KK6 A;  4G1M B;  1N1I A;  4ZH8 B;  1KLO A;  4JYU L;  1EPI A;  1NFU B;  1L5G B;  1URK A;  1XKB A;  3GIS X;  3LIW B;  5IKQ A;  2WG4 B;  2XBY L;  2UWO B;  2Y81 B;  3KL6 B;  3FCS B;  2WFX B;  3N8V A;  1IOX A;  1LPG A;  5JBC E;  1LQD A;  2FLR L;  2PHB B;  2MHP A;  2J34 B;  1K36 A;  1IQN L;  1G1Q A;  4ZAE B;  1M1X B;  4LOR A;  1EMN A;  1G1T A;  1G2L B;  2P95 L;  4X8V L;  2Y82 B;  4MMY B;  1HAF A;  5CKM A;  3OLU A;  4C16 A;  4CSY A;  3NTG A;  4JZE L;  1FSB A;  2B7D L;  2WPH E;  6COX A;  5F19 A;  4YT7 L;  1CQE A;  1DX5 I;  4Y6D B;  3N8Z A;  2VH6 B;  1PRH A;  2XC0 L;  1F0S B;  2K2T A;  5IKR A;  2I9B A;  2XC4 L;  3ZYJ B;  1LMJ A;  4RUT A;  1EAI C;  1XFE A;  5EGM B;  3N8W A;  3HS7 A;  3NJP C;  1DDX A;  4ISH L;  2CJI B;  1IQG L;  4FM5 A;  1BF9 A;  3NTB A;  2BMG A;  4YZU B;  2P3F L;  1DQB A;  5JB8 E;  5IKT A;  1WHF A;  2WYJ B;  5COX A;  3LC3 B;  3HO3 A;  2W2P E;  2BOX A;  3FFG L;  4XL1 A;  4LMF A;  1NFX B;  3LTF B;  2BZ6 L;  4O1Z A;  2XBX L;  4ZHA B;  5KN5 C;  4OTJ A;  1C5M F;  1WHE A;  2EI7 B;  1Z6E L;  2VJ3 A;  2P93 L;  2VH0 B;  2ADX A;  1O5D L;  1AUT L;  1IVO C;  3F6U L;  2VWN L;  5CIS A;  1L3Y A;  2P94 L;  1MQ5 L;  1XKA L;  4CUF A;  5I46 L;  3KQD L;  3BT1 A;  2KV4 A;  1NQL B;  3ENS A;  3SOV A;  4E1G A;  1B9W A;  5CKN A;  1YUG A;  1IQM L;  2P3T A;  2Y5F L;  2P26 A;  2KL7 A;  3TK5 B;  5JVZ A;  2BOH A;  3Q3K B;  2BOK L;  1YUK B;  2BO2 A;  2Y7X B;  3CA7 A;  3CFW A;  1APO A;  1N7D A;  1WU1 B;  3DEM A;  2PUQ L;  3KQC L;  5JB9 E;  2W2M E;  2MGR A;  1MQ6 L;  2W2N E;  1IOE L;  3GCX E;  2WPM E;  1ATB A;  1KIG L;  4XLW A;  3KQB L;  1NZI A;  3TBD A;  1FE2 A;  4MMZ B;  4Y76 B;  1CEJ A;  3ZYG A;  3POY A;  3LAQ A;  1JL9 A;  3U7U G;  2MGP A;  3V64 C;  1DIY A;  1P9J A;  3HO5 A;  2BOU A;  2FZZ L;  1HJ7 A;  3TH3 L;  1IQH L;  2UWP B;  4ZXY L;  1UZJ A;  4JZF L;  2W2O E;  4TGF A;  2AYL A;  2FD6 A;  2FLG A;  4MMX B;  2VVU L;  1ATA A;  1V3X B;  2VWM K;  4M10 A;  3U73 A;  3ZYI B;  2WFT A;  4AQT A;  3RR3 A;  4BTT A;  3FBY A;  4XBM A;  5L2Y L;  4JZD L;  1J9C L;  4O02 B;  3KCG L;  3N8Y B;  1HCG B;  1X7A L;  1ZAQ A;  4NA9 L;  1KLJ L;  3Q7D A;  1YGC L;  2WPL E;  2H9E L;  2J2U B;  2UWL B;  4RS0 A;  1EZQ B;  2RHP A;  1G1S A;  1Q4G A;  1NFY B;  1TOZ A;  1IQF L;  2JKH L;  3H5C B;  1IQE L;  3F1S B;  2DDU A;  3P5B L;  3LTG D;  1JV2 B;  4PH9 A;  3NT1 A;  5L30 L;  2P3F N;  1OB1 C;  3LN1 A;  4YT6 L;  5F1A A;  2WPJ E;  2OYU P;  5IKV A;  2VWL L;  1TPG A;  4COX A;  1NT0 A;  4D0F A;  1U8C B;  2Y5G L;  1G2M B;  3CEN L;  2Y80 B;  5JBB E;  3N8X A;  3HS6 A;  4X8S L;  2G00 L;  1CCF A;  3C9A C;  2D1J B;  2Y7Z B;  1G1R A;  2XC5 L;  4JYV L;  3TK6 B;  1ADX A;  1F7M A;  3KQE L;  4Y79 B;  1A3P A;  2VVV L;  1KSN B;  2OYE P;  4CUD A;  2F9B L;  4BXS A;  1CX2 A;  2Y38 A;  1U67 A;  2RA0 L;  1IP0 A;  1EMO A;  1IJQ A;  1COU A;  3SOB B;  2NPR A;  3TGF A;  2I9A A;  3K9X A;  1PFX L;  1ATE A;  1K37 A;  4Z6A L;  3HS5 A;  1W8B L;  3HO4 A;  1ATD A;  2M74 A;  3QCW A;  1YUF A;  1EBV A;  1EGF A;  2W3K B;  2EI6 B;  4NG9 L;  5KIR A;  2W26 B;  1TLE A; 
#chains in the Genus database with same CATH topology
 1FAX L;  3N8W B;  1XDT R;  4Y7B B;  3V65 B;  1APQ A;  1EPJ A;  1FFM A;  2GD4 A;  5E8D A;  2XBV L;  4Y7A B;  1JBU L;  2Q1J B;  1QFK L;  4CUE A;  2KB9 A;  3ELA L;  1UZQ A;  3MQE A;  2P3U A;  1F7E A;  4RRX A;  5JBA E;  2WPK E;  5K0H B;  1NFW B;  3PGH A;  1Z6C A;  4RRZ A;  2P16 L;  5FDQ A;  4X8U L;  1RFN B;  5CKQ A;  1SZB A;  1EQH A;  4ISI L;  4RRY A;  2W86 A;  3R05 A;  1IQJ L;  1PTH A;  1FAK L;  3EGF A;  3SOQ A;  4RRW A;  4BDW A;  1W7X L;  1P0S L;  2J38 B;  3GCW E;  4NGA L;  2WYG B;  3QH0 A;  1PXX A;  2EI8 B;  2J94 B;  3IJE B;  3M36 L;  1HT8 A;  2VVC K;  1HRE A;  1LPK A;  4Y71 B;  2WG3 C;  3LC5 B;  4BXW A;  1HX2 A;  2BQW A;  3BPS E;  1KKE A;  1MOX C;  1KLI L;  1IQI L;  2WPI E;  4Z0L A;  1I0U A;  1EPH A;  1EPG A;  2YGO A;  2FLB L;  3HPT A;  3KRK A;  1GK5 A;  3LN0 A;  1CVW L;  4ZXX L;  4A7I A;  1UZP A;  3CS7 L;  1CVU A;  1DVA L;  4OTY A;  2VWO L;  2J95 B;  3OLT A;  2RNL A;  2BQ7 A;  1HAE A;  1HRF A;  2K2S B;  3N8Y A;  5L2Z L;  2TGF A;  2W3I B;  3QMO A;  2Y5H L;  1FF7 A;  1IGZ A;  1LPZ A;  1FJS L;  3IIT B;  4X8T L;  1UZK A;  1HZ8 A;  1PGE A;  3ASI A;  1LK9 A;  2YGP A;  3SW2 A;  4BDX A;  5JW1 A;  2W2Q E;  1IGX A;  3MDL A;  4GU3 A;  1LMM A;  4BTU A;  1NPE B;  1IQL L;  2PR3 B;  3TZI A;  1HT5 A;  1CCV A;  2P28 B;  1IQK L;  3M37 L;  2J4I B;  4D90 A;  3BT2 A;  4D0E A;  4BTI A;  1F0R B;  4Z0K B;  1YO8 A;  5JVY A;  2BQ6 A;  4M11 A;  1EQG A;  2XBW L;  3KK6 A;  4G1M B;  1N1I A;  4ZH8 B;  1KLO A;  2BT7 A;  2HOR A;  4JYU L;  1EPI A;  1NFU B;  2JJL A;  1L5G B;  1URK A;  1XKB A;  3GIS X;  3LIW B;  5IKQ A;  2WG4 B;  2XBY L;  2UWO B;  2Y81 B;  3KL6 B;  3FCS B;  2WFX B;  3N8V A;  1IOX A;  1LPG A;  5JBC E;  1LQD A;  2FLR L;  2PHB B;  2MHP A;  2J34 B;  1K36 A;  1IQN L;  1G1Q A;  4ZAE B;  1M1X B;  4LOR A;  1EMN A;  1G1T A;  1G2L B;  2P95 L;  4X8V L;  2Y82 B;  2BSF A;  2VRS A;  4MMY B;  1HAF A;  5CKM A;  3OLU A;  4C16 A;  4CSY A;  3NTG A;  4JZE L;  1FSB A;  2B7D L;  2WPH E;  6COX A;  5F19 A;  4YT7 L;  1CQE A;  1DX5 I;  4Y6D B;  3N8Z A;  2VH6 B;  1PRH A;  2XC0 L;  1F0S B;  2K2T A;  5IKR A;  2I9B A;  2XC4 L;  3ZYJ B;  1LMJ A;  4RUT A;  1EAI C;  1XFE A;  5EGM B;  3N8W A;  3HS7 A;  3NJP C;  1DDX A;  4ISH L;  2CJI B;  1IQG L;  4FM5 A;  1BF9 A;  4GU4 A;  3NTB A;  2BMG A;  4YZU B;  2P3F L;  1DQB A;  5JB8 E;  5IKT A;  1WHF A;  2WYJ B;  5COX A;  3LC3 B;  3HO3 A;  2W2P E;  2BOX A;  3FFG L;  4XL1 A;  4LMF A;  1NFX B;  3LTF B;  2BZ6 L;  4O1Z A;  2XBX L;  2HOX A;  2YGQ A;  4ZHA B;  5KN5 C;  4OTJ A;  1C5M F;  1WHE A;  2EI7 B;  1Z6E L;  2VJ3 A;  2P93 L;  2VH0 B;  2ADX A;  1O5D L;  1AUT L;  1IVO C;  3F6U L;  2VWN L;  5CIS A;  1L3Y A;  2P94 L;  1MQ5 L;  1XKA L;  4CUF A;  5I46 L;  3KQD L;  3BT1 A;  1QIU A;  2KV4 A;  1NQL B;  3ENS A;  3SOV A;  4E1G A;  1B9W A;  5CKN A;  1YUG A;  1IQM L;  2P3T A;  2Y5F L;  2P26 A;  2KL7 A;  3TK5 B;  5JVZ A;  2BOH A;  3Q3K B;  2BOK L;  4A94 C;  1YUK B;  2BO2 A;  2Y7X B;  3CA7 A;  3CFW A;  1APO A;  1N7D A;  1WU1 B;  3DEM A;  2PUQ L;  3KQC L;  5JB9 E;  1V1H A;  2H9E C;  2W2M E;  2MGR A;  1MQ6 L;  2W2N E;  1IOE L;  3GCX E;  2WPM E;  1ATB A;  1KIG L;  4XLW A;  3KQB L;  1NZI A;  3TBD A;  1FE2 A;  4MMZ B;  4Y76 B;  1CEJ A;  3ZYG A;  3POY A;  3LAQ A;  1JL9 A;  3U7U G;  2MGP A;  3V64 C;  1DIY A;  1P9J A;  3HO5 A;  2BOU A;  2FZZ L;  1HJ7 A;  3TH3 L;  1IQH L;  2UWP B;  4ZXY L;  1UZJ A;  4JZF L;  2W2O E;  4TGF A;  2AYL A;  2FD6 A;  2FLG A;  4MMX B;  2VVU L;  1ATA A;  1V3X B;  2VWM K;  4M10 A;  3U73 A;  3S6X A;  3ZYI B;  2WFT A;  4AQT A;  3RR3 A;  4BTT A;  3FBY A;  4XBM A;  5L2Y L;  4JZD L;  1J9C L;  4O02 B;  3KCG L;  3N8Y B;  1V1I A;  1HCG B;  1X7A L;  1ZAQ A;  4NA9 L;  1KLJ L;  3Q7D A;  1YGC L;  2WPL E;  2H9E L;  2J2U B;  2UWL B;  4RS0 A;  1EZQ B;  2RHP A;  1G1S A;  1Q4G A;  1NFY B;  1TOZ A;  1IQF L;  2JKH L;  3H5C B;  1IQE L;  3F1S B;  2DDU A;  3P5B L;  3LTG D;  1JV2 B;  4PH9 A;  3NT1 A;  5L30 L;  2P3F N;  2KNI A;  1OB1 C;  3LN1 A;  4YT6 L;  5F1A A;  2WPJ E;  2OYU P;  5IKV A;  2VWL L;  1TPG A;  4COX A;  1NT0 A;  2WZP P;  4D0F A;  1U8C B;  2Y5G L;  1G2M B;  3CEN L;  2Y80 B;  5JBB E;  3N8X A;  3HS6 A;  4X8S L;  2G00 L;  1CCF A;  3C9A C;  2D1J B;  2Y7Z B;  1G1R A;  2BT8 A;  2XC5 L;  4JYV L;  3TK6 B;  1ADX A;  1F7M A;  3KQE L;  4Y79 B;  1A3P A;  2VVV L;  1KSN B;  2OYE P;  4CUD A;  2F9B L;  4BXS A;  1CX2 A;  2Y38 A;  1U67 A;  2RA0 L;  1IP0 A;  1EMO A;  1IJQ A;  1COU A;  3SOB B;  2NPR A;  3TGF A;  2I9A A;  3K9X A;  1PFX L;  1ATE A;  1K37 A;  4Z6A L;  3HS5 A;  1W8B L;  3HO4 A;  1ATD A;  2M74 A;  3QCW A;  1YUF A;  1EBV A;  1EGF A;  2W3K B;  2EI6 B;  4NG9 L;  5KIR A;  2W26 B;  1TLE A; 
#chains in the Genus database with same CATH homology
 1FAX L;  3N8W B;  1XDT R;  4Y7B B;  3V65 B;  1APQ A;  1EPJ A;  1FFM A;  2GD4 A;  5E8D A;  2XBV L;  4Y7A B;  1JBU L;  2Q1J B;  1QFK L;  4CUE A;  2KB9 A;  3ELA L;  1UZQ A;  3MQE A;  2P3U A;  1F7E A;  4RRX A;  5JBA E;  2WPK E;  5K0H B;  1NFW B;  3PGH A;  1Z6C A;  4RRZ A;  2P16 L;  5FDQ A;  4X8U L;  1RFN B;  5CKQ A;  1SZB A;  1EQH A;  4ISI L;  4RRY A;  2W86 A;  3R05 A;  1IQJ L;  1PTH A;  1FAK L;  3EGF A;  3SOQ A;  4RRW A;  4BDW A;  1W7X L;  1P0S L;  2J38 B;  3GCW E;  4NGA L;  2WYG B;  3QH0 A;  1PXX A;  2EI8 B;  2J94 B;  3IJE B;  3M36 L;  1HT8 A;  2VVC K;  1HRE A;  1LPK A;  4Y71 B;  2WG3 C;  3LC5 B;  4BXW A;  1HX2 A;  2BQW A;  3BPS E;  1MOX C;  1KLI L;  1IQI L;  2WPI E;  4Z0L A;  1I0U A;  1EPH A;  1EPG A;  2YGO A;  2FLB L;  3HPT A;  3KRK A;  1GK5 A;  3LN0 A;  1CVW L;  4ZXX L;  4A7I A;  1UZP A;  3CS7 L;  1CVU A;  1DVA L;  4OTY A;  2VWO L;  2J95 B;  3OLT A;  2RNL A;  2BQ7 A;  1HAE A;  1HRF A;  2K2S B;  3N8Y A;  5L2Z L;  2TGF A;  2W3I B;  3QMO A;  2Y5H L;  1FF7 A;  1IGZ A;  1LPZ A;  1FJS L;  3IIT B;  4X8T L;  1UZK A;  1HZ8 A;  1PGE A;  3ASI A;  2YGP A;  3SW2 A;  4BDX A;  5JW1 A;  2W2Q E;  1IGX A;  3MDL A;  1LMM A;  4BTU A;  1NPE B;  1IQL L;  2PR3 B;  3TZI A;  1HT5 A;  1CCV A;  2P28 B;  1IQK L;  3M37 L;  2J4I B;  4D90 A;  3BT2 A;  4D0E A;  4BTI A;  1F0R B;  4Z0K B;  1YO8 A;  5JVY A;  2BQ6 A;  4M11 A;  1EQG A;  2XBW L;  3KK6 A;  4G1M B;  1N1I A;  4ZH8 B;  1KLO A;  4JYU L;  1EPI A;  1NFU B;  1L5G B;  1URK A;  1XKB A;  3GIS X;  3LIW B;  5IKQ A;  2WG4 B;  2XBY L;  2UWO B;  2Y81 B;  3KL6 B;  3FCS B;  2WFX B;  3N8V A;  1IOX A;  1LPG A;  5JBC E;  1LQD A;  2FLR L;  2PHB B;  2MHP A;  2J34 B;  1K36 A;  1IQN L;  1G1Q A;  4ZAE B;  1M1X B;  4LOR A;  1EMN A;  1G1T A;  1G2L B;  2P95 L;  4X8V L;  2Y82 B;  4MMY B;  1HAF A;  5CKM A;  3OLU A;  4C16 A;  4CSY A;  3NTG A;  4JZE L;  1FSB A;  2B7D L;  2WPH E;  6COX A;  5F19 A;  4YT7 L;  1CQE A;  1DX5 I;  4Y6D B;  3N8Z A;  2VH6 B;  1PRH A;  2XC0 L;  1F0S B;  2K2T A;  5IKR A;  2I9B A;  2XC4 L;  3ZYJ B;  1LMJ A;  4RUT A;  1EAI C;  1XFE A;  5EGM B;  3N8W A;  3HS7 A;  3NJP C;  1DDX A;  4ISH L;  2CJI B;  1IQG L;  4FM5 A;  1BF9 A;  3NTB A;  2BMG A;  4YZU B;  2P3F L;  1DQB A;  5JB8 E;  5IKT A;  1WHF A;  2WYJ B;  5COX A;  3LC3 B;  3HO3 A;  2W2P E;  2BOX A;  3FFG L;  4XL1 A;  4LMF A;  1NFX B;  3LTF B;  2BZ6 L;  4O1Z A;  2XBX L;  2YGQ A;  4ZHA B;  5KN5 C;  4OTJ A;  1C5M F;  1WHE A;  2EI7 B;  1Z6E L;  2VJ3 A;  2P93 L;  2VH0 B;  2ADX A;  1O5D L;  1AUT L;  1IVO C;  3F6U L;  2VWN L;  5CIS A;  1L3Y A;  2P94 L;  1MQ5 L;  1XKA L;  4CUF A;  5I46 L;  3KQD L;  3BT1 A;  2KV4 A;  1NQL B;  3ENS A;  3SOV A;  4E1G A;  1B9W A;  5CKN A;  1YUG A;  1IQM L;  2P3T A;  2Y5F L;  2P26 A;  2KL7 A;  3TK5 B;  5JVZ A;  2BOH A;  3Q3K B;  2BOK L;  4A94 C;  1YUK B;  2BO2 A;  2Y7X B;  3CA7 A;  3CFW A;  1APO A;  1N7D A;  1WU1 B;  3DEM A;  2PUQ L;  3KQC L;  5JB9 E;  2H9E C;  2W2M E;  2MGR A;  1MQ6 L;  2W2N E;  1IOE L;  3GCX E;  2WPM E;  1ATB A;  1KIG L;  4XLW A;  3KQB L;  1NZI A;  3TBD A;  1FE2 A;  4MMZ B;  4Y76 B;  1CEJ A;  3ZYG A;  3POY A;  3LAQ A;  1JL9 A;  3U7U G;  2MGP A;  3V64 C;  1DIY A;  1P9J A;  3HO5 A;  2BOU A;  2FZZ L;  1HJ7 A;  3TH3 L;  1IQH L;  2UWP B;  4ZXY L;  1UZJ A;  4JZF L;  2W2O E;  4TGF A;  2AYL A;  2FD6 A;  2FLG A;  4MMX B;  2VVU L;  1ATA A;  1V3X B;  2VWM K;  4M10 A;  3U73 A;  3S6X A;  3ZYI B;  2WFT A;  4AQT A;  3RR3 A;  4BTT A;  3FBY A;  4XBM A;  5L2Y L;  4JZD L;  1J9C L;  4O02 B;  3KCG L;  3N8Y B;  1HCG B;  1X7A L;  1ZAQ A;  4NA9 L;  1KLJ L;  3Q7D A;  1YGC L;  2WPL E;  2H9E L;  2J2U B;  2UWL B;  4RS0 A;  1EZQ B;  2RHP A;  1G1S A;  1Q4G A;  1NFY B;  1TOZ A;  1IQF L;  2JKH L;  3H5C B;  1IQE L;  3F1S B;  2DDU A;  3P5B L;  3LTG D;  1JV2 B;  4PH9 A;  3NT1 A;  5L30 L;  2P3F N;  2KNI A;  1OB1 C;  3LN1 A;  4YT6 L;  5F1A A;  2WPJ E;  2OYU P;  5IKV A;  2VWL L;  1TPG A;  4COX A;  1NT0 A;  2WZP P;  4D0F A;  1U8C B;  2Y5G L;  1G2M B;  3CEN L;  2Y80 B;  5JBB E;  3N8X A;  3HS6 A;  4X8S L;  2G00 L;  1CCF A;  3C9A C;  2D1J B;  2Y7Z B;  1G1R A;  2XC5 L;  4JYV L;  3TK6 B;  1ADX A;  1F7M A;  3KQE L;  4Y79 B;  1A3P A;  2VVV L;  1KSN B;  2OYE P;  4CUD A;  2F9B L;  4BXS A;  1CX2 A;  2Y38 A;  1U67 A;  2RA0 L;  1IP0 A;  1EMO A;  1IJQ A;  1COU A;  3SOB B;  2NPR A;  3TGF A;  2I9A A;  3K9X A;  1PFX L;  1ATE A;  1K37 A;  4Z6A L;  3HS5 A;  1W8B L;  3HO4 A;  1ATD A;  2M74 A;  3QCW A;  1YUF A;  1EBV A;  1EGF A;  2W3K B;  2EI6 B;  4NG9 L;  5KIR A;  2W26 B;  1TLE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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