2Y81B

Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Aminoindane and Phenylpyrrolidine P4 Motifs.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2011-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00008 EGF EGF-like domain
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2y81B00
3BT1A 4YZUB 3MQEA 2WPJE 2Y5HL 3FBYA 4O02B 4RS0A 1EQGA 3GCXE 3TH3L 3GCWE 5F19A 4MMXB 3LC3B 4MMYB 1ATBA 3ENSA 2W2PE 1ATEA 3LN1A 1FJSL 4Z0KB 5JVZA 3N8XA 2MGPA 2TGFA 1APOA 1CCFA 3KQDL 4MMZB 1IQML 3MDLA 1APQA 5CISA 2MHPA 1G1TA 4XL1A 3N8YA 4ZH8B 2UWPB 1G2LB 1HCGB 3Q7DA 3TZIA 2D1JB 2WYJB 1N1IA 3NTBA 1HAEA 2VH6B 4XBMA 1PFXL 2WYGB 5JB9E 4O1ZA 2FLRL 1G1SA 1MQ5L 1B9WA 4Y76B 2XC4L 1LPGA 2Y38A 5IKVA 1NPEB 3KRKA 3ZYIB 1G1RA 3NJPC 3EGFA 2EI7B 5K0HB 3CA7A 1EPHA 2B7DL 2FD6A 2K2TA 4RRXA 3N8WB 3M37L 1KLJL 4JZDL 1WHEA 2W86A 3LTGD 3POYA 2BOXA 5JBCE 2CJIB 2WPHE 5JB8E 4A7IA 1UZQA 2FLGA 4FM5A 1LQDA 1F0SB 3GISX 2FZZL 3TK5B 4X8VL 4Z6AL 4OTJA 2P3FN 3FCSB 2J2UB 2WPKE 3V65B 3ZYGA 3QCWA 4RUTA 4D0FA 1K37A 1PRHA 3BPSE 3HPTA 4YT7L 1X7AL 1LMJA 2Y7ZB 4CSYA 2P3TA 3SW2A 2VVUL 1G2MB 1Z6CA 2OYUP 3PGHA 4RRYA 2J4IB 4E1GA 2VWMK 2UWOB 4Y7AB 3M36L 2GD4A 1ADXA 2W26B 1IQJL 1YUKB 3OLTA 1DDXA 2M74A 2ADXA 3IITB 2W2NE 2RA0L 1HJ7A 1IQGL 3N8VA 1JV2B 4BTUA 1KSNB 1NQLB 2P3UA 2BQ6A 4NGAL 1L5GB 3V64C 4Z0LA 3F6UL 1MOXC 2W3KB 1URKA 3HO4A 2WPME 5EGMB 4BDXA 2VH0B 1W8BL 2MGRA 5IKQA 3HO3A 3N8WA 3ZYJB 2Y81B 1IOEL 2VJ3A 2P93L 4BXSA 1V3XB 1ATAA 1LPKA 2J38B 1XFEA 1DQBA 1YO8A 3OLUA 1PXXA 4LMFA 4TGFA 1U67A 2YGOA 2P16L 1UZJA 3TGFA 1COUA 2WFXB 4LORA 1EQHA 2K2SB 1UZPA 1EAIC 3P5BL 2XC5L 5CKNA 1F7EA 1FF7A 1HT8A 2BQWA 3HO5A 3CFWA 1K36A 1DVAL 1HT5A 1C5MF 5JVYA 1IQKL 1TLEA 3C9AC 1JBUL 1Z6EL 2BOUA 2J34B 3QMOA 1XKAL 1P0SL 4YT6L 1TOZA 1XDTR 3KK6A 3ASIA 1IOXA 1M1XB 1NFXB 1FSBA 2BO2A 2XBVL 1W7XL 1EMNA 5CKMA 3BT2A 4X8SL 3LIWB 3R05A 1WHFA 4BTTA 4ZHAB 3KQEL 3FFGL 6COXA 1KIGL 1CVWL 3NTGA 2BOKL 1FFMA 4Y71B 2PHBB 1PGEA 4AQTA 3U73A 1YUGA 2W3IB 5KN5C 4NG9L 3KQBL 3SOBB 2EI6B 1RFNB 1KLOA 3QH0A 4OTYA 2W2ME 1P9JA 1EPJA 4Y6DB 2Y5FL 2Y7XB 3F1SB 5JBBE 1DX5I 2BQ7A 3NT1A 1LPZA 1EBVA 4XLWA 3U7UG 4X8TL 1MQ6L 2DDUA 3RR3A 4COXA 2BZ6L 4JZEL 1HAFA 4JYVL 1N7DA 2BMGA 4RRWA 4CUFA 1HX2A 1WU1B 1SZBA 2I9AA 2RNLA 5CKQA 4M11A 1YGCL 1EZQB 1TPGA 2P26A 2EI8B 3SOVA 1GK5A 2WPLE 1JL9A 3KCGL 2RHPA 1CVUA 2P28B 2WFTA 1IQNL 2XC0L 1HREA 5COXA 1XKBA 5L2YL 3LAQA 4D0EA 4CUDA 1YUFA 5IKTA 2PR3B 2YGPA 4JZFL 3TBDA 4ISHL 5E8DA 3IJEB 3TK6B 2VWLL 2W2QE 1EGFA 1CX2A 2Q1JB 1IVOC 4Y79B 1IQLL 1IQEL 2PUQL 5L2ZL 5L30L 2WPIE 2KV4A 2KB9A 1NFUB 5IKRA 2P95L 1Q4GA 4M10A 1FAKL 1BF9A 4ISIL 2UWLB 3K9XA 3HS5A 5JW1A 1CQEA 1CCVA 1IJQA 1IGXA 2Y82B 4C16A 1NFYB 1I0UA 3CENL 5KIRA 2BOHA 3KL6B 2NPRA 3LN0A 2Y5GL 4D90A 2FLBL 2W2OE 2Y80B 4X8UL 4Y7BB 4RRZA 2XBYL 5JBAE 2AYLA 4BDWA 2WG4B 4PH9A 3LC5B 4JYUL 1NZIA 4BXWA 3Q3KB 3ELAL 3HS7A 3N8YB 4CUEA 1DIYA 1U8CB 1NT0A 2G00L 2I9BA 2J94B 2OYEP 1OB1C 1IQFL 1QFKL 4ZXXL 1J9CL 1AUTL 1NFWB 1G1QA 3SOQA 2WG3C 1L3YA 4ZAEB 2VVCK 1ZAQA 2F9BL 2XBWL 2P3FL 1HRFA 1IP0A 1EMOA 3H5CB 1EPIA 1F0RB 2P94L 3HS6A 3N8ZA 3LTFB 2H9EL 1UZKA 1O5DL 1ATDA 5F1AA 1KLIL 3KQCL 1CEJA 2KL7A 3DEMA 1EPGA 2J95B 2JKHL 1IGZA 1HZ8A 1FAXL 4ZXYL 1A3PA 5FDQA 2VVVL 4BTIA 1F7MA 3CS7L 4NA9L 1IQIL 2VWNL 1IQHL 1PTHA 2VWOL 2XBXL 4G1MB 1FE2A 5I46L
chains in the Genus database with same CATH superfamily
3BT1A 4YZUB 3MQEA 2WPJE 2Y5HL 3FBYA 4O02B 4RS0A 1EQGA 3GCXE 3TH3L 3GCWE 5F19A 4MMXB 3LC3B 4MMYB 1ATBA 3ENSA 2W2PE 1ATEA 3LN1A 1FJSL 4Z0KB 5JVZA 3N8XA 2MGPA 2TGFA 1APOA 1CCFA 3KQDL 4MMZB 1IQML 3MDLA 1APQA 5CISA 2MHPA 1G1TA 4XL1A 3N8YA 4ZH8B 2UWPB 1G2LB 1HCGB 3Q7DA 3TZIA 2D1JB 2WYJB 1N1IA 3NTBA 1HAEA 1QIUA 2VH6B 4XBMA 1PFXL 2WYGB 5JB9E 4O1ZA 2FLRL 1G1SA 1MQ5L 1B9WA 4Y76B 2XC4L 1LPGA 2Y38A 5IKVA 3KRKA 1NPEB 3ZYIB 2HOXA 1G1RA 3NJPC 3EGFA 2EI7B 5K0HB 3CA7A 1EPHA 2B7DL 2FD6A 2K2TA 4RRXA 3N8WB 3M37L 1KLJL 4JZDL 1WHEA 2W86A 3LTGD 3POYA 2BOXA 5JBCE 2CJIB 2WPHE 5JB8E 4A7IA 1UZQA 2FLGA 1KKEA 4FM5A 1LQDA 1F0SB 3GISX 2FZZL 3TK5B 4X8VL 4Z6AL 4OTJA 2P3FN 3FCSB 2J2UB 2WPKE 3V65B 3ZYGA 4A94C 3QCWA 4RUTA 4D0FA 1K37A 1PRHA 3BPSE 3HPTA 4YT7L 1X7AL 1LMJA 2Y7ZB 4CSYA 2P3TA 3SW2A 2VVUL 1G2MB 1Z6CA 2OYUP 3PGHA 4RRYA 2J4IB 4E1GA 2VWMK 2HORA 2UWOB 4Y7AB 3M36L 2GD4A 1ADXA 2W26B 1IQJL 1YUKB 3OLTA 1DDXA 2M74A 2ADXA 3IITB 2W2NE 2RA0L 1HJ7A 1IQGL 3N8VA 1JV2B 4BTUA 1KSNB 1NQLB 2P3UA 2BQ6A 4NGAL 1L5GB 3V64C 4Z0LA 3F6UL 1MOXC 2W3KB 2YGQA 1URKA 3HO4A 2WPME 5EGMB 4BDXA 2VH0B 1W8BL 2MGRA 5IKQA 3HO3A 3N8WA 3ZYJB 2Y81B 1IOEL 2VJ3A 2P93L 4BXSA 1V3XB 1ATAA 1LPKA 2J38B 1XFEA 1DQBA 2BSFA 1YO8A 3OLUA 1PXXA 4LMFA 2WZPP 4TGFA 1U67A 2YGOA 2P16L 1UZJA 3TGFA 1COUA 2WFXB 4LORA 1EQHA 2K2SB 1UZPA 1EAIC 3P5BL 2XC5L 5CKNA 1F7EA 1LK9A 1FF7A 1HT8A 2BQWA 3HO5A 2JJLA 3CFWA 1K36A 1DVAL 1HT5A 1C5MF 5JVYA 1IQKL 1TLEA 3C9AC 1JBUL 1Z6EL 2BOUA 2J34B 3QMOA 1XKAL 1P0SL 4YT6L 1TOZA 1XDTR 3KK6A 3ASIA 1IOXA 1M1XB 1NFXB 2KNIA 1FSBA 2BO2A 2XBVL 1W7XL 1EMNA 5CKMA 3BT2A 4X8SL 3LIWB 3R05A 1WHFA 4BTTA 4ZHAB 3KQEL 3FFGL 6COXA 1KIGL 1CVWL 3NTGA 2BOKL 1FFMA 4Y71B 2PHBB 1PGEA 4AQTA 3U73A 1YUGA 2W3IB 5KN5C 4NG9L 3KQBL 3SOBB 2EI6B 1RFNB 1KLOA 3QH0A 4OTYA 2W2ME 1P9JA 1EPJA 4Y6DB 2Y5FL 2Y7XB 3F1SB 5JBBE 1DX5I 2BQ7A 3NT1A 1LPZA 1EBVA 4XLWA 3U7UG 4X8TL 1MQ6L 2DDUA 3RR3A 4COXA 2BZ6L 4JZEL 1HAFA 4JYVL 1N7DA 2BT7A 2BT8A 2BMGA 4RRWA 4CUFA 1HX2A 1WU1B 1SZBA 2I9AA 2RNLA 5CKQA 4M11A 1YGCL 1EZQB 1TPGA 2P26A 2EI8B 3SOVA 1GK5A 2WPLE 1JL9A 3KCGL 2RHPA 1CVUA 2P28B 2WFTA 1IQNL 2XC0L 3S6XA 1HREA 4GU4A 5COXA 1V1HA 1XKBA 5L2YL 3LAQA 4D0EA 4CUDA 1YUFA 5IKTA 2PR3B 2YGPA 4JZFL 3TBDA 4ISHL 5E8DA 3IJEB 3TK6B 2VWLL 2W2QE 1EGFA 1CX2A 2Q1JB 1IVOC 4Y79B 1IQLL 1IQEL 2PUQL 5L2ZL 5L30L 2WPIE 2KV4A 2KB9A 1NFUB 5IKRA 2P95L 1Q4GA 4M10A 1FAKL 1BF9A 4ISIL 2UWLB 3K9XA 3HS5A 5JW1A 1CQEA 1CCVA 1IJQA 1IGXA 2Y82B 4C16A 1NFYB 1I0UA 3CENL 5KIRA 2BOHA 3KL6B 2NPRA 3LN0A 2Y5GL 4D90A 2FLBL 2W2OE 2Y80B 4X8UL 4Y7BB 4RRZA 2XBYL 5JBAE 2AYLA 4BDWA 2WG4B 4PH9A 3LC5B 4JYUL 1NZIA 4BXWA 3Q3KB 3ELAL 1V1IA 3HS7A 3N8YB 4CUEA 1DIYA 1U8CB 1NT0A 2G00L 2I9BA 2J94B 2OYEP 1OB1C 1IQFL 1QFKL 4ZXXL 1J9CL 1AUTL 1NFWB 1G1QA 3SOQA 2WG3C 1L3YA 4ZAEB 2VVCK 1ZAQA 2F9BL 2XBWL 2P3FL 1HRFA 1IP0A 1EMOA 3H5CB 1EPIA 1F0RB 2P94L 3HS6A 3N8ZA 3LTFB 2H9EL 1UZKA 1O5DL 1ATDA 5F1AA 1KLIL 3KQCL 1CEJA 2KL7A 3DEMA 1EPGA 2J95B 2JKHL 1IGZA 1HZ8A 1FAXL 4ZXYL 1A3PA 5FDQA 2VVVL 4BTIA 1F7MA 3CS7L 4NA9L 1IQIL 2VWNL 4GU3A 1IQHL 1PTHA 2VWOL 2XBXL 2H9EC 4G1MB 2VRSA 1LMMA 1FE2A 5I46L
chains in the Genus database with same CATH topology
3BT1A 4YZUB 3MQEA 2WPJE 2Y5HL 3FBYA 4O02B 4RS0A 1EQGA 3GCXE 3TH3L 3GCWE 5F19A 4MMXB 3LC3B 4MMYB 1ATBA 3ENSA 2W2PE 1ATEA 3LN1A 1FJSL 4Z0KB 5JVZA 3N8XA 2MGPA 2TGFA 1APOA 1CCFA 3KQDL 4MMZB 1IQML 3MDLA 1APQA 5CISA 2MHPA 1G1TA 4XL1A 3N8YA 4ZH8B 2UWPB 1G2LB 1HCGB 3Q7DA 3TZIA 2D1JB 2WYJB 1N1IA 3NTBA 1HAEA 2VH6B 4XBMA 1PFXL 2WYGB 5JB9E 4O1ZA 2FLRL 1G1SA 1MQ5L 1B9WA 4Y76B 2XC4L 1LPGA 2Y38A 5IKVA 1NPEB 3KRKA 3ZYIB 1G1RA 3NJPC 3EGFA 2EI7B 5K0HB 3CA7A 1EPHA 2B7DL 2FD6A 2K2TA 4RRXA 3N8WB 3M37L 1KLJL 4JZDL 1WHEA 2W86A 3LTGD 3POYA 2BOXA 5JBCE 2CJIB 2WPHE 5JB8E 4A7IA 1UZQA 2FLGA 4FM5A 1LQDA 1F0SB 3GISX 2FZZL 3TK5B 4X8VL 4Z6AL 4OTJA 2P3FN 3FCSB 2J2UB 2WPKE 3V65B 3ZYGA 4A94C 3QCWA 4RUTA 4D0FA 1K37A 1PRHA 3BPSE 3HPTA 4YT7L 1X7AL 1LMJA 2Y7ZB 4CSYA 2P3TA 3SW2A 2VVUL 1G2MB 1Z6CA 2OYUP 3PGHA 4RRYA 2J4IB 4E1GA 2VWMK 2UWOB 4Y7AB 3M36L 2GD4A 1ADXA 2W26B 1IQJL 1YUKB 3OLTA 1DDXA 2M74A 2ADXA 3IITB 2W2NE 2RA0L 1HJ7A 1IQGL 3N8VA 1JV2B 4BTUA 1KSNB 1NQLB 2P3UA 2BQ6A 4NGAL 1L5GB 3V64C 4Z0LA 3F6UL 1MOXC 2W3KB 2YGQA 1URKA 3HO4A 2WPME 5EGMB 4BDXA 2VH0B 1W8BL 2MGRA 5IKQA 3HO3A 3N8WA 3ZYJB 2Y81B 1IOEL 2VJ3A 2P93L 4BXSA 1V3XB 1ATAA 1LPKA 2J38B 1XFEA 1DQBA 1YO8A 3OLUA 1PXXA 4LMFA 2WZPP 4TGFA 1U67A 2YGOA 2P16L 1UZJA 3TGFA 1COUA 2WFXB 4LORA 1EQHA 2K2SB 1UZPA 1EAIC 3P5BL 2XC5L 5CKNA 1F7EA 1FF7A 1HT8A 2BQWA 3HO5A 3CFWA 1K36A 1DVAL 1HT5A 1C5MF 5JVYA 1IQKL 1TLEA 3C9AC 1JBUL 1Z6EL 2BOUA 2J34B 3QMOA 1XKAL 1P0SL 4YT6L 1TOZA 1XDTR 3KK6A 3ASIA 1IOXA 1M1XB 1NFXB 2KNIA 1FSBA 2BO2A 2XBVL 1W7XL 1EMNA 5CKMA 3BT2A 4X8SL 3LIWB 3R05A 1WHFA 4BTTA 4ZHAB 3KQEL 3FFGL 6COXA 1KIGL 1CVWL 3NTGA 2BOKL 1FFMA 4Y71B 2PHBB 1PGEA 4AQTA 3U73A 1YUGA 2W3IB 5KN5C 4NG9L 3KQBL 3SOBB 2EI6B 1RFNB 1KLOA 3QH0A 4OTYA 2W2ME 1P9JA 1EPJA 4Y6DB 2Y5FL 2Y7XB 3F1SB 5JBBE 1DX5I 2BQ7A 3NT1A 1LPZA 1EBVA 4XLWA 3U7UG 4X8TL 1MQ6L 2DDUA 3RR3A 4COXA 2BZ6L 4JZEL 1HAFA 4JYVL 1N7DA 2BMGA 4RRWA 4CUFA 1HX2A 1WU1B 1SZBA 2I9AA 2RNLA 5CKQA 4M11A 1YGCL 1EZQB 1TPGA 2P26A 2EI8B 3SOVA 1GK5A 2WPLE 1JL9A 3KCGL 2RHPA 1CVUA 2P28B 2WFTA 1IQNL 2XC0L 3S6XA 1HREA 5COXA 1XKBA 5L2YL 3LAQA 4D0EA 4CUDA 1YUFA 5IKTA 2PR3B 2YGPA 4JZFL 3TBDA 4ISHL 5E8DA 3IJEB 3TK6B 2VWLL 2W2QE 1EGFA 1CX2A 2Q1JB 1IVOC 4Y79B 1IQLL 1IQEL 2PUQL 5L2ZL 5L30L 2WPIE 2KV4A 2KB9A 1NFUB 5IKRA 2P95L 1Q4GA 4M10A 1FAKL 1BF9A 4ISIL 2UWLB 3K9XA 3HS5A 5JW1A 1CQEA 1CCVA 1IJQA 1IGXA 2Y82B 4C16A 1NFYB 1I0UA 3CENL 5KIRA 2BOHA 3KL6B 2NPRA 3LN0A 2Y5GL 4D90A 2FLBL 2W2OE 2Y80B 4X8UL 4Y7BB 4RRZA 2XBYL 5JBAE 2AYLA 4BDWA 2WG4B 4PH9A 3LC5B 4JYUL 1NZIA 4BXWA 3Q3KB 3ELAL 3HS7A 3N8YB 4CUEA 1DIYA 1U8CB 1NT0A 2G00L 2I9BA 2J94B 2OYEP 1OB1C 1IQFL 1QFKL 4ZXXL 1J9CL 1AUTL 1NFWB 1G1QA 3SOQA 2WG3C 1L3YA 4ZAEB 2VVCK 1ZAQA 2F9BL 2XBWL 2P3FL 1HRFA 1IP0A 1EMOA 3H5CB 1EPIA 1F0RB 2P94L 3HS6A 3N8ZA 3LTFB 2H9EL 1UZKA 1O5DL 1ATDA 5F1AA 1KLIL 3KQCL 1CEJA 2KL7A 3DEMA 1EPGA 2J95B 2JKHL 1IGZA 1HZ8A 1FAXL 4ZXYL 1A3PA 5FDQA 2VVVL 4BTIA 1F7MA 3CS7L 4NA9L 1IQIL 2VWNL 1IQHL 1PTHA 2VWOL 2XBXL 2H9EC 4G1MB 1LMMA 1FE2A 5I46L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BT1 A;  4YZU B;  3MQE A;  2WPJ E;  2Y5H L;  3FBY A;  4O02 B;  4RS0 A;  1EQG A;  3GCX E;  3TH3 L;  3GCW E;  5F19 A;  4MMX B;  3LC3 B;  4MMY B;  1ATB A;  3ENS A;  2W2P E;  1ATE A;  3LN1 A;  1FJS L;  4Z0K B;  5JVZ A;  3N8X A;  2MGP A;  2TGF A;  1APO A;  1CCF A;  3KQD L;  4MMZ B;  1IQM L;  3MDL A;  1APQ A;  5CIS A;  2MHP A;  1G1T A;  4XL1 A;  3N8Y A;  4ZH8 B;  2UWP B;  1G2L B;  1HCG B;  3Q7D A;  3TZI A;  2D1J B;  2WYJ B;  1N1I A;  3NTB A;  1HAE A;  2VH6 B;  4XBM A;  1PFX L;  2WYG B;  5JB9 E;  4O1Z A;  2FLR L;  1G1S A;  1MQ5 L;  1B9W A;  4Y76 B;  2XC4 L;  1LPG A;  2Y38 A;  5IKV A;  1NPE B;  3KRK A;  3ZYI B;  1G1R A;  3NJP C;  3EGF A;  2EI7 B;  5K0H B;  3CA7 A;  1EPH A;  2B7D L;  2FD6 A;  2K2T A;  4RRX A;  3N8W B;  3M37 L;  1KLJ L;  4JZD L;  1WHE A;  2W86 A;  3LTG D;  3POY A;  2BOX A;  5JBC E;  2CJI B;  2WPH E;  5JB8 E;  4A7I A;  1UZQ A;  2FLG A;  4FM5 A;  1LQD A;  1F0S B;  3GIS X;  2FZZ L;  3TK5 B;  4X8V L;  4Z6A L;  4OTJ A;  2P3F N;  3FCS B;  2J2U B;  2WPK E;  3V65 B;  3ZYG A;  3QCW A;  4RUT A;  4D0F A;  1K37 A;  1PRH A;  3BPS E;  3HPT A;  4YT7 L;  1X7A L;  1LMJ A;  2Y7Z B;  4CSY A;  2P3T A;  3SW2 A;  2VVU L;  1G2M B;  1Z6C A;  2OYU P;  3PGH A;  4RRY A;  2J4I B;  4E1G A;  2VWM K;  2UWO B;  4Y7A B;  3M36 L;  2GD4 A;  1ADX A;  2W26 B;  1IQJ L;  1YUK B;  3OLT A;  1DDX A;  2M74 A;  2ADX A;  3IIT B;  2W2N E;  2RA0 L;  1HJ7 A;  1IQG L;  3N8V A;  1JV2 B;  4BTU A;  1KSN B;  1NQL B;  2P3U A;  2BQ6 A;  4NGA L;  1L5G B;  3V64 C;  4Z0L A;  3F6U L;  1MOX C;  2W3K B;  1URK A;  3HO4 A;  2WPM E;  5EGM B;  4BDX A;  2VH0 B;  1W8B L;  2MGR A;  5IKQ A;  3HO3 A;  3N8W A;  3ZYJ B;  2Y81 B;  1IOE L;  2VJ3 A;  2P93 L;  4BXS A;  1V3X B;  1ATA A;  1LPK A;  2J38 B;  1XFE A;  1DQB A;  1YO8 A;  3OLU A;  1PXX A;  4LMF A;  4TGF A;  1U67 A;  2YGO A;  2P16 L;  1UZJ A;  3TGF A;  1COU A;  2WFX B;  4LOR A;  1EQH A;  2K2S B;  1UZP A;  1EAI C;  3P5B L;  2XC5 L;  5CKN A;  1F7E A;  1FF7 A;  1HT8 A;  2BQW A;  3HO5 A;  3CFW A;  1K36 A;  1DVA L;  1HT5 A;  1C5M F;  5JVY A;  1IQK L;  1TLE A;  3C9A C;  1JBU L;  1Z6E L;  2BOU A;  2J34 B;  3QMO A;  1XKA L;  1P0S L;  4YT6 L;  1TOZ A;  1XDT R;  3KK6 A;  3ASI A;  1IOX A;  1M1X B;  1NFX B;  1FSB A;  2BO2 A;  2XBV L;  1W7X L;  1EMN A;  5CKM A;  3BT2 A;  4X8S L;  3LIW B;  3R05 A;  1WHF A;  4BTT A;  4ZHA B;  3KQE L;  3FFG L;  6COX A;  1KIG L;  1CVW L;  3NTG A;  2BOK L;  1FFM A;  4Y71 B;  2PHB B;  1PGE A;  4AQT A;  3U73 A;  1YUG A;  2W3I B;  5KN5 C;  4NG9 L;  3KQB L;  3SOB B;  2EI6 B;  1RFN B;  1KLO A;  3QH0 A;  4OTY A;  2W2M E;  1P9J A;  1EPJ A;  4Y6D B;  2Y5F L;  2Y7X B;  3F1S B;  5JBB E;  1DX5 I;  2BQ7 A;  3NT1 A;  1LPZ A;  1EBV A;  4XLW A;  3U7U G;  4X8T L;  1MQ6 L;  2DDU A;  3RR3 A;  4COX A;  2BZ6 L;  4JZE L;  1HAF A;  4JYV L;  1N7D A;  2BMG A;  4RRW A;  4CUF A;  1HX2 A;  1WU1 B;  1SZB A;  2I9A A;  2RNL A;  5CKQ A;  4M11 A;  1YGC L;  1EZQ B;  1TPG A;  2P26 A;  2EI8 B;  3SOV A;  1GK5 A;  2WPL E;  1JL9 A;  3KCG L;  2RHP A;  1CVU A;  2P28 B;  2WFT A;  1IQN L;  2XC0 L;  1HRE A;  5COX A;  1XKB A;  5L2Y L;  3LAQ A;  4D0E A;  4CUD A;  1YUF A;  5IKT A;  2PR3 B;  2YGP A;  4JZF L;  3TBD A;  4ISH L;  5E8D A;  3IJE B;  3TK6 B;  2VWL L;  2W2Q E;  1EGF A;  1CX2 A;  2Q1J B;  1IVO C;  4Y79 B;  1IQL L;  1IQE L;  2PUQ L;  5L2Z L;  5L30 L;  2WPI E;  2KV4 A;  2KB9 A;  1NFU B;  5IKR A;  2P95 L;  1Q4G A;  4M10 A;  1FAK L;  1BF9 A;  4ISI L;  2UWL B;  3K9X A;  3HS5 A;  5JW1 A;  1CQE A;  1CCV A;  1IJQ A;  1IGX A;  2Y82 B;  4C16 A;  1NFY B;  1I0U A;  3CEN L;  5KIR A;  2BOH A;  3KL6 B;  2NPR A;  3LN0 A;  2Y5G L;  4D90 A;  2FLB L;  2W2O E;  2Y80 B;  4X8U L;  4Y7B B;  4RRZ A;  2XBY L;  5JBA E;  2AYL A;  4BDW A;  2WG4 B;  4PH9 A;  3LC5 B;  4JYU L;  1NZI A;  4BXW A;  3Q3K B;  3ELA L;  3HS7 A;  3N8Y B;  4CUE A;  1DIY A;  1U8C B;  1NT0 A;  2G00 L;  2I9B A;  2J94 B;  2OYE P;  1OB1 C;  1IQF L;  1QFK L;  4ZXX L;  1J9C L;  1AUT L;  1NFW B;  1G1Q A;  3SOQ A;  2WG3 C;  1L3Y A;  4ZAE B;  2VVC K;  1ZAQ A;  2F9B L;  2XBW L;  2P3F L;  1HRF A;  1IP0 A;  1EMO A;  3H5C B;  1EPI A;  1F0R B;  2P94 L;  3HS6 A;  3N8Z A;  3LTF B;  2H9E L;  1UZK A;  1O5D L;  1ATD A;  5F1A A;  1KLI L;  3KQC L;  1CEJ A;  2KL7 A;  3DEM A;  1EPG A;  2J95 B;  2JKH L;  1IGZ A;  1HZ8 A;  1FAX L;  4ZXY L;  1A3P A;  5FDQ A;  2VVV L;  4BTI A;  1F7M A;  3CS7 L;  4NA9 L;  1IQI L;  2VWN L;  1IQH L;  1PTH A;  2VWO L;  2XBX L;  4G1M B;  1FE2 A;  5I46 L; 
#chains in the Genus database with same CATH topology
 3BT1 A;  4YZU B;  3MQE A;  2WPJ E;  2Y5H L;  3FBY A;  4O02 B;  4RS0 A;  1EQG A;  3GCX E;  3TH3 L;  3GCW E;  5F19 A;  4MMX B;  3LC3 B;  4MMY B;  1ATB A;  3ENS A;  2W2P E;  1ATE A;  3LN1 A;  1FJS L;  4Z0K B;  5JVZ A;  3N8X A;  2MGP A;  2TGF A;  1APO A;  1CCF A;  3KQD L;  4MMZ B;  1IQM L;  3MDL A;  1APQ A;  5CIS A;  2MHP A;  1G1T A;  4XL1 A;  3N8Y A;  4ZH8 B;  2UWP B;  1G2L B;  1HCG B;  3Q7D A;  3TZI A;  2D1J B;  2WYJ B;  1N1I A;  3NTB A;  1HAE A;  1QIU A;  2VH6 B;  4XBM A;  1PFX L;  2WYG B;  5JB9 E;  4O1Z A;  2FLR L;  1G1S A;  1MQ5 L;  1B9W A;  4Y76 B;  2XC4 L;  1LPG A;  2Y38 A;  5IKV A;  3KRK A;  1NPE B;  3ZYI B;  2HOX A;  1G1R A;  3NJP C;  3EGF A;  2EI7 B;  5K0H B;  3CA7 A;  1EPH A;  2B7D L;  2FD6 A;  2K2T A;  4RRX A;  3N8W B;  3M37 L;  1KLJ L;  4JZD L;  1WHE A;  2W86 A;  3LTG D;  3POY A;  2BOX A;  5JBC E;  2CJI B;  2WPH E;  5JB8 E;  4A7I A;  1UZQ A;  2FLG A;  1KKE A;  4FM5 A;  1LQD A;  1F0S B;  3GIS X;  2FZZ L;  3TK5 B;  4X8V L;  4Z6A L;  4OTJ A;  2P3F N;  3FCS B;  2J2U B;  2WPK E;  3V65 B;  3ZYG A;  4A94 C;  3QCW A;  4RUT A;  4D0F A;  1K37 A;  1PRH A;  3BPS E;  3HPT A;  4YT7 L;  1X7A L;  1LMJ A;  2Y7Z B;  4CSY A;  2P3T A;  3SW2 A;  2VVU L;  1G2M B;  1Z6C A;  2OYU P;  3PGH A;  4RRY A;  2J4I B;  4E1G A;  2VWM K;  2HOR A;  2UWO B;  4Y7A B;  3M36 L;  2GD4 A;  1ADX A;  2W26 B;  1IQJ L;  1YUK B;  3OLT A;  1DDX A;  2M74 A;  2ADX A;  3IIT B;  2W2N E;  2RA0 L;  1HJ7 A;  1IQG L;  3N8V A;  1JV2 B;  4BTU A;  1KSN B;  1NQL B;  2P3U A;  2BQ6 A;  4NGA L;  1L5G B;  3V64 C;  4Z0L A;  3F6U L;  1MOX C;  2W3K B;  2YGQ A;  1URK A;  3HO4 A;  2WPM E;  5EGM B;  4BDX A;  2VH0 B;  1W8B L;  2MGR A;  5IKQ A;  3HO3 A;  3N8W A;  3ZYJ B;  2Y81 B;  1IOE L;  2VJ3 A;  2P93 L;  4BXS A;  1V3X B;  1ATA A;  1LPK A;  2J38 B;  1XFE A;  1DQB A;  2BSF A;  1YO8 A;  3OLU A;  1PXX A;  4LMF A;  2WZP P;  4TGF A;  1U67 A;  2YGO A;  2P16 L;  1UZJ A;  3TGF A;  1COU A;  2WFX B;  4LOR A;  1EQH A;  2K2S B;  1UZP A;  1EAI C;  3P5B L;  2XC5 L;  5CKN A;  1F7E A;  1LK9 A;  1FF7 A;  1HT8 A;  2BQW A;  3HO5 A;  2JJL A;  3CFW A;  1K36 A;  1DVA L;  1HT5 A;  1C5M F;  5JVY A;  1IQK L;  1TLE A;  3C9A C;  1JBU L;  1Z6E L;  2BOU A;  2J34 B;  3QMO A;  1XKA L;  1P0S L;  4YT6 L;  1TOZ A;  1XDT R;  3KK6 A;  3ASI A;  1IOX A;  1M1X B;  1NFX B;  2KNI A;  1FSB A;  2BO2 A;  2XBV L;  1W7X L;  1EMN A;  5CKM A;  3BT2 A;  4X8S L;  3LIW B;  3R05 A;  1WHF A;  4BTT A;  4ZHA B;  3KQE L;  3FFG L;  6COX A;  1KIG L;  1CVW L;  3NTG A;  2BOK L;  1FFM A;  4Y71 B;  2PHB B;  1PGE A;  4AQT A;  3U73 A;  1YUG A;  2W3I B;  5KN5 C;  4NG9 L;  3KQB L;  3SOB B;  2EI6 B;  1RFN B;  1KLO A;  3QH0 A;  4OTY A;  2W2M E;  1P9J A;  1EPJ A;  4Y6D B;  2Y5F L;  2Y7X B;  3F1S B;  5JBB E;  1DX5 I;  2BQ7 A;  3NT1 A;  1LPZ A;  1EBV A;  4XLW A;  3U7U G;  4X8T L;  1MQ6 L;  2DDU A;  3RR3 A;  4COX A;  2BZ6 L;  4JZE L;  1HAF A;  4JYV L;  1N7D A;  2BT7 A;  2BT8 A;  2BMG A;  4RRW A;  4CUF A;  1HX2 A;  1WU1 B;  1SZB A;  2I9A A;  2RNL A;  5CKQ A;  4M11 A;  1YGC L;  1EZQ B;  1TPG A;  2P26 A;  2EI8 B;  3SOV A;  1GK5 A;  2WPL E;  1JL9 A;  3KCG L;  2RHP A;  1CVU A;  2P28 B;  2WFT A;  1IQN L;  2XC0 L;  3S6X A;  1HRE A;  4GU4 A;  5COX A;  1V1H A;  1XKB A;  5L2Y L;  3LAQ A;  4D0E A;  4CUD A;  1YUF A;  5IKT A;  2PR3 B;  2YGP A;  4JZF L;  3TBD A;  4ISH L;  5E8D A;  3IJE B;  3TK6 B;  2VWL L;  2W2Q E;  1EGF A;  1CX2 A;  2Q1J B;  1IVO C;  4Y79 B;  1IQL L;  1IQE L;  2PUQ L;  5L2Z L;  5L30 L;  2WPI E;  2KV4 A;  2KB9 A;  1NFU B;  5IKR A;  2P95 L;  1Q4G A;  4M10 A;  1FAK L;  1BF9 A;  4ISI L;  2UWL B;  3K9X A;  3HS5 A;  5JW1 A;  1CQE A;  1CCV A;  1IJQ A;  1IGX A;  2Y82 B;  4C16 A;  1NFY B;  1I0U A;  3CEN L;  5KIR A;  2BOH A;  3KL6 B;  2NPR A;  3LN0 A;  2Y5G L;  4D90 A;  2FLB L;  2W2O E;  2Y80 B;  4X8U L;  4Y7B B;  4RRZ A;  2XBY L;  5JBA E;  2AYL A;  4BDW A;  2WG4 B;  4PH9 A;  3LC5 B;  4JYU L;  1NZI A;  4BXW A;  3Q3K B;  3ELA L;  1V1I A;  3HS7 A;  3N8Y B;  4CUE A;  1DIY A;  1U8C B;  1NT0 A;  2G00 L;  2I9B A;  2J94 B;  2OYE P;  1OB1 C;  1IQF L;  1QFK L;  4ZXX L;  1J9C L;  1AUT L;  1NFW B;  1G1Q A;  3SOQ A;  2WG3 C;  1L3Y A;  4ZAE B;  2VVC K;  1ZAQ A;  2F9B L;  2XBW L;  2P3F L;  1HRF A;  1IP0 A;  1EMO A;  3H5C B;  1EPI A;  1F0R B;  2P94 L;  3HS6 A;  3N8Z A;  3LTF B;  2H9E L;  1UZK A;  1O5D L;  1ATD A;  5F1A A;  1KLI L;  3KQC L;  1CEJ A;  2KL7 A;  3DEM A;  1EPG A;  2J95 B;  2JKH L;  1IGZ A;  1HZ8 A;  1FAX L;  4ZXY L;  1A3P A;  5FDQ A;  2VVV L;  4BTI A;  1F7M A;  3CS7 L;  4NA9 L;  1IQI L;  2VWN L;  4GU3 A;  1IQH L;  1PTH A;  2VWO L;  2XBX L;  2H9E C;  4G1M B;  2VRS A;  1LMM A;  1FE2 A;  5I46 L; 
#chains in the Genus database with same CATH homology
 3BT1 A;  4YZU B;  3MQE A;  2WPJ E;  2Y5H L;  3FBY A;  4O02 B;  4RS0 A;  1EQG A;  3GCX E;  3TH3 L;  3GCW E;  5F19 A;  4MMX B;  3LC3 B;  4MMY B;  1ATB A;  3ENS A;  2W2P E;  1ATE A;  3LN1 A;  1FJS L;  4Z0K B;  5JVZ A;  3N8X A;  2MGP A;  2TGF A;  1APO A;  1CCF A;  3KQD L;  4MMZ B;  1IQM L;  3MDL A;  1APQ A;  5CIS A;  2MHP A;  1G1T A;  4XL1 A;  3N8Y A;  4ZH8 B;  2UWP B;  1G2L B;  1HCG B;  3Q7D A;  3TZI A;  2D1J B;  2WYJ B;  1N1I A;  3NTB A;  1HAE A;  2VH6 B;  4XBM A;  1PFX L;  2WYG B;  5JB9 E;  4O1Z A;  2FLR L;  1G1S A;  1MQ5 L;  1B9W A;  4Y76 B;  2XC4 L;  1LPG A;  2Y38 A;  5IKV A;  1NPE B;  3KRK A;  3ZYI B;  1G1R A;  3NJP C;  3EGF A;  2EI7 B;  5K0H B;  3CA7 A;  1EPH A;  2B7D L;  2FD6 A;  2K2T A;  4RRX A;  3N8W B;  3M37 L;  1KLJ L;  4JZD L;  1WHE A;  2W86 A;  3LTG D;  3POY A;  2BOX A;  5JBC E;  2CJI B;  2WPH E;  5JB8 E;  4A7I A;  1UZQ A;  2FLG A;  4FM5 A;  1LQD A;  1F0S B;  3GIS X;  2FZZ L;  3TK5 B;  4X8V L;  4Z6A L;  4OTJ A;  2P3F N;  3FCS B;  2J2U B;  2WPK E;  3V65 B;  3ZYG A;  4A94 C;  3QCW A;  4RUT A;  4D0F A;  1K37 A;  1PRH A;  3BPS E;  3HPT A;  4YT7 L;  1X7A L;  1LMJ A;  2Y7Z B;  4CSY A;  2P3T A;  3SW2 A;  2VVU L;  1G2M B;  1Z6C A;  2OYU P;  3PGH A;  4RRY A;  2J4I B;  4E1G A;  2VWM K;  2UWO B;  4Y7A B;  3M36 L;  2GD4 A;  1ADX A;  2W26 B;  1IQJ L;  1YUK B;  3OLT A;  1DDX A;  2M74 A;  2ADX A;  3IIT B;  2W2N E;  2RA0 L;  1HJ7 A;  1IQG L;  3N8V A;  1JV2 B;  4BTU A;  1KSN B;  1NQL B;  2P3U A;  2BQ6 A;  4NGA L;  1L5G B;  3V64 C;  4Z0L A;  3F6U L;  1MOX C;  2W3K B;  2YGQ A;  1URK A;  3HO4 A;  2WPM E;  5EGM B;  4BDX A;  2VH0 B;  1W8B L;  2MGR A;  5IKQ A;  3HO3 A;  3N8W A;  3ZYJ B;  2Y81 B;  1IOE L;  2VJ3 A;  2P93 L;  4BXS A;  1V3X B;  1ATA A;  1LPK A;  2J38 B;  1XFE A;  1DQB A;  1YO8 A;  3OLU A;  1PXX A;  4LMF A;  2WZP P;  4TGF A;  1U67 A;  2YGO A;  2P16 L;  1UZJ A;  3TGF A;  1COU A;  2WFX B;  4LOR A;  1EQH A;  2K2S B;  1UZP A;  1EAI C;  3P5B L;  2XC5 L;  5CKN A;  1F7E A;  1FF7 A;  1HT8 A;  2BQW A;  3HO5 A;  3CFW A;  1K36 A;  1DVA L;  1HT5 A;  1C5M F;  5JVY A;  1IQK L;  1TLE A;  3C9A C;  1JBU L;  1Z6E L;  2BOU A;  2J34 B;  3QMO A;  1XKA L;  1P0S L;  4YT6 L;  1TOZ A;  1XDT R;  3KK6 A;  3ASI A;  1IOX A;  1M1X B;  1NFX B;  2KNI A;  1FSB A;  2BO2 A;  2XBV L;  1W7X L;  1EMN A;  5CKM A;  3BT2 A;  4X8S L;  3LIW B;  3R05 A;  1WHF A;  4BTT A;  4ZHA B;  3KQE L;  3FFG L;  6COX A;  1KIG L;  1CVW L;  3NTG A;  2BOK L;  1FFM A;  4Y71 B;  2PHB B;  1PGE A;  4AQT A;  3U73 A;  1YUG A;  2W3I B;  5KN5 C;  4NG9 L;  3KQB L;  3SOB B;  2EI6 B;  1RFN B;  1KLO A;  3QH0 A;  4OTY A;  2W2M E;  1P9J A;  1EPJ A;  4Y6D B;  2Y5F L;  2Y7X B;  3F1S B;  5JBB E;  1DX5 I;  2BQ7 A;  3NT1 A;  1LPZ A;  1EBV A;  4XLW A;  3U7U G;  4X8T L;  1MQ6 L;  2DDU A;  3RR3 A;  4COX A;  2BZ6 L;  4JZE L;  1HAF A;  4JYV L;  1N7D A;  2BMG A;  4RRW A;  4CUF A;  1HX2 A;  1WU1 B;  1SZB A;  2I9A A;  2RNL A;  5CKQ A;  4M11 A;  1YGC L;  1EZQ B;  1TPG A;  2P26 A;  2EI8 B;  3SOV A;  1GK5 A;  2WPL E;  1JL9 A;  3KCG L;  2RHP A;  1CVU A;  2P28 B;  2WFT A;  1IQN L;  2XC0 L;  3S6X A;  1HRE A;  5COX A;  1XKB A;  5L2Y L;  3LAQ A;  4D0E A;  4CUD A;  1YUF A;  5IKT A;  2PR3 B;  2YGP A;  4JZF L;  3TBD A;  4ISH L;  5E8D A;  3IJE B;  3TK6 B;  2VWL L;  2W2Q E;  1EGF A;  1CX2 A;  2Q1J B;  1IVO C;  4Y79 B;  1IQL L;  1IQE L;  2PUQ L;  5L2Z L;  5L30 L;  2WPI E;  2KV4 A;  2KB9 A;  1NFU B;  5IKR A;  2P95 L;  1Q4G A;  4M10 A;  1FAK L;  1BF9 A;  4ISI L;  2UWL B;  3K9X A;  3HS5 A;  5JW1 A;  1CQE A;  1CCV A;  1IJQ A;  1IGX A;  2Y82 B;  4C16 A;  1NFY B;  1I0U A;  3CEN L;  5KIR A;  2BOH A;  3KL6 B;  2NPR A;  3LN0 A;  2Y5G L;  4D90 A;  2FLB L;  2W2O E;  2Y80 B;  4X8U L;  4Y7B B;  4RRZ A;  2XBY L;  5JBA E;  2AYL A;  4BDW A;  2WG4 B;  4PH9 A;  3LC5 B;  4JYU L;  1NZI A;  4BXW A;  3Q3K B;  3ELA L;  3HS7 A;  3N8Y B;  4CUE A;  1DIY A;  1U8C B;  1NT0 A;  2G00 L;  2I9B A;  2J94 B;  2OYE P;  1OB1 C;  1IQF L;  1QFK L;  4ZXX L;  1J9C L;  1AUT L;  1NFW B;  1G1Q A;  3SOQ A;  2WG3 C;  1L3Y A;  4ZAE B;  2VVC K;  1ZAQ A;  2F9B L;  2XBW L;  2P3F L;  1HRF A;  1IP0 A;  1EMO A;  3H5C B;  1EPI A;  1F0R B;  2P94 L;  3HS6 A;  3N8Z A;  3LTF B;  2H9E L;  1UZK A;  1O5D L;  1ATD A;  5F1A A;  1KLI L;  3KQC L;  1CEJ A;  2KL7 A;  3DEM A;  1EPG A;  2J95 B;  2JKH L;  1IGZ A;  1HZ8 A;  1FAX L;  4ZXY L;  1A3P A;  5FDQ A;  2VVV L;  4BTI A;  1F7M A;  3CS7 L;  4NA9 L;  1IQI L;  2VWN L;  1IQH L;  1PTH A;  2VWO L;  2XBX L;  2H9E C;  4G1M B;  1LMM A;  1FE2 A;  5I46 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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